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Conserved domains on  [gi|219882427|gb|ACL52332|]
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NADH dehydrogenase subunit 2, partial (mitochondrion) [Melozone kieneri]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475904)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 1.04e-163

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 460.83  E-value: 1.04e-163
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427   1 MNPQANSIFITSLLLGTTITISSNHWIMAWMGLEINTLAILPLISKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWY 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427  81 TGQWDITQLTHPTSCLILTSAVAMKLGLVPFHFWFPEVLQGSPLTTGLLLSTLMKLPPITLLYMTSPSLNPTLLTTLAIL 160
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427 161 SAALGGWMGLNQTQVRKILAFSSISHLGWMAIVIIYNPKLTLLNFYLYTMMTAAVFLTLNTIKVSKLSTLMTTWTKIPSL 240
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427 241 NTMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATLISLLSLLSLFFYLRLAYCTAITLPPHTTNHMKQWRTNKP 320
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                        330       340
                 ....*....|....*....|....*.
gi 219882427 321 TNITIAMLITMSIALLPISPMILTIV 346
Cdd:MTH00112 321 KNTLTATLTTLSTLLLPLSPMILTII 346
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 1.04e-163

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 460.83  E-value: 1.04e-163
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427   1 MNPQANSIFITSLLLGTTITISSNHWIMAWMGLEINTLAILPLISKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWY 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427  81 TGQWDITQLTHPTSCLILTSAVAMKLGLVPFHFWFPEVLQGSPLTTGLLLSTLMKLPPITLLYMTSPSLNPTLLTTLAIL 160
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427 161 SAALGGWMGLNQTQVRKILAFSSISHLGWMAIVIIYNPKLTLLNFYLYTMMTAAVFLTLNTIKVSKLSTLMTTWTKIPSL 240
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427 241 NTMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATLISLLSLLSLFFYLRLAYCTAITLPPHTTNHMKQWRTNKP 320
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                        330       340
                 ....*....|....*....|....*.
gi 219882427 321 TNITIAMLITMSIALLPISPMILTIV 346
Cdd:MTH00112 321 KNTLTATLTTLSTLLLPLSPMILTII 346
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-268 2.98e-24

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 100.47  E-value: 2.98e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427   23 SNHWIMAWMGLEINTLAILPLI-SKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWYTGQWDITQL-----------T 90
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELskaltgglnssG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427   91 HPTSCLILTSAVAMKLGLVPFHFWFPEVLQGSPLTTGLLLSTLMKLPPITLLYMTSPSLNPT------LLTTLAILSAAL 164
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAATLVKAGGYGLIRRSLLYLPSspfiqqILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427  165 GGWMGLNQTQVRKILAFSSISHLGWM----AIVIIYNPKLTLLNFYLYTMMTAAVFLTLNTIKVSKLST-----LMTTWT 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMlialGAGTIYGIQAAIFHLLTHGLFSAGLFLCAGSVIYRRVHTrnirdYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 219882427  236 KIPSLNTMLLLTLLSLAGLPPLTGFLPKWLIIQ 268
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 14-298 1.29e-21

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 95.18  E-value: 1.29e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427  14 LLGTTITISSNHWIMAWMGLEINTLAILPLIS-KSHHPRAIEAATKYFLTQAAASALVLF-SSMTNAwYTGQWDITQLTH 91
Cdd:COG1007  112 TLGMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgISLLYG-ATGSLNLAGIAA 190

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427  92 PTS------------CLILTSAVAMKLGLVPFHFWFPEVLQGSPlttglllstlmklPPIT-----------------LL 142
Cdd:COG1007  191 ALAagganspllllgLVLVLAGLAFKLSAVPFHMWTPDVYEGAP-------------TPVTaflatapkiaafaallrLL 257

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427 143 YMTSPSLNP---TLLTTLAILSAALGGWMGLNQTQVRKILAFSSISHLGWMAIVIIYNPKLTL--LNFYL--YTMMTAAV 215
Cdd:COG1007  258 VEAFPGLAAdwqLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLGVsaALFYLlaYLFMNLGA 337

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427 216 FLTLntIKVSKLSTLMTTWTKI-------PSLNTMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATLISLLSLL 288
Cdd:COG1007  338 FAVI--LLLSRKGGEAEEIEDLaglarrsPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVI 415

                        330
                 ....*....|
gi 219882427 289 SLFFYLRLAY 298
Cdd:COG1007  416 SAYYYLRVVK 425
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 14-297 2.90e-19

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 88.47  E-value: 2.90e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427   14 LLGTTITISSNHWIMAWMGLEINTLAILPLIS-KSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWYTGQWDITQLTHP 92
Cdd:TIGR01770 112 LLGIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLLF 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427   93 TSCLILT------------SAVAMKLGLVPFHFWFPEVLQGSPLTTGLLLSTLMKLP---PITLLYMTSPS----LNPTL 153
Cdd:TIGR01770 192 LSNGMLNisllllgivlilVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAifaVFLRLFLYILFgfseAWQIF 271

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427  154 LTTLAILSAALGGWMGLNQTQVRKILAFSSISHLGWMAIVIIYNPKLTLLN--FYL--YTMMTAAVFLTLNTIKVSK--- 226
Cdd:TIGR01770 272 LAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAvlFYIfiYALMSLGAFGVLSLLRSYKdew 351

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 219882427  227 ---LSTLMTTWTKIPSLNTMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATLISLLSLLSLFFYLRLA 297
Cdd:TIGR01770 352 ieyISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVV 425
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 1.04e-163

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 460.83  E-value: 1.04e-163
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427   1 MNPQANSIFITSLLLGTTITISSNHWIMAWMGLEINTLAILPLISKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWY 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427  81 TGQWDITQLTHPTSCLILTSAVAMKLGLVPFHFWFPEVLQGSPLTTGLLLSTLMKLPPITLLYMTSPSLNPTLLTTLAIL 160
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427 161 SAALGGWMGLNQTQVRKILAFSSISHLGWMAIVIIYNPKLTLLNFYLYTMMTAAVFLTLNTIKVSKLSTLMTTWTKIPSL 240
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427 241 NTMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATLISLLSLLSLFFYLRLAYCTAITLPPHTTNHMKQWRTNKP 320
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                        330       340
                 ....*....|....*....|....*.
gi 219882427 321 TNITIAMLITMSIALLPISPMILTIV 346
Cdd:MTH00112 321 KNTLTATLTTLSTLLLPLSPMILTII 346
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-346 1.18e-133

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 384.54  E-value: 1.18e-133
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427   1 MNPQANSIFITSLLLGTTITISSNHWIMAWMGLEINTLAILPLISKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWY 80
Cdd:MTH00135   1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427  81 TGQWDITQLTHPTSCLILTSAVAMKLGLVPFHFWFPEVLQGSPLTTGLLLSTLMKLPPITLLYMTSPSlNPTLLTTLAIL 160
Cdd:MTH00135  81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPT-NPTLLITLGLT 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427 161 SAALGGWMGLNQTQVRKILAFSSISHLGWMAIVIIYNPKLTLLNFYLYTMMTAAVFLTLNTIKVSKLSTLMTTWTKIPSL 240
Cdd:MTH00135 160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPAL 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427 241 NTMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATLISLLSLLSLFFYLRLAYCTAITLPPHTTNHMKQWRTNKP 320
Cdd:MTH00135 240 TALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPST 319

                        330       340
                 ....*....|....*....|....*..
gi 219882427 321 -TNITIAMLITMSIALLPISPMILTIV 346
Cdd:MTH00135 320 qLTLPLAISTTATLMLLPLTPAILALL 346
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-345 2.42e-132

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 381.19  E-value: 2.42e-132
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427   1 MNPQANSIFITSLLLGTTITISSNHWIMAWMGLEINTLAILPLISKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWY 80
Cdd:MTH00070   1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427  81 TGQWDITQLTHPTSCLILTSAVAMKLGLVPFHFWFPEVLQGSPLTTGLLLSTLMKLPPITLLYMTSPSLNPTLLTTLAIL 160
Cdd:MTH00070  81 TGEWTIMNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427 161 SAALGGWMGLNQTQVRKILAFSSISHLGWMAIVIIYNPKLTLLNFYLYTMMTAAVFLTLNTIKVSKLSTLMTTWTKIPSL 240
Cdd:MTH00070 161 STLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427 241 NTMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATLISLLSLLSLFFYLRLAYCTAITLPPHTTNHMKQWRTNKP 320
Cdd:MTH00070 241 TSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRFKNK 320

                        330       340
                 ....*....|....*....|....*
gi 219882427 321 TNITIAMLITMSIALLPISPMILTI 345
Cdd:MTH00070 321 TNNLLSLTIILSLMLLPITPTILNL 345
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-345 4.94e-116

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 339.51  E-value: 4.94e-116
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427   1 MNPQANSIFITSLLLGTTITISSNHWIMAWMGLEINTLAILPLISKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWY 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427  81 TGQWDITQLTHPTSCLILTSAVAMKLGLVPFHFWFPEVLQGSPLTTGLLLSTLMKLPPITLLYMTSPSLNPTLLTTLAIL 160
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427 161 SAALGGWMGLNQTQVRKILAFSSISHLGWMAIVIIYNPKLTLLNFYLYTMMTAAVFLTLNTIKVSKLSTLMTTWTKIPSL 240
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427 241 NTMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATLISLLSLLSLFFYLRLAYCTAITLPPhTTNHMK-QWR-TN 318
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFP-STNNMKmKWQfEN 319

                        330       340
                 ....*....|....*....|....*..
gi 219882427 319 KPTNITIAMLITMSIALLPISPMILTI 345
Cdd:MTH00105 320 TKPMTLLPTLIILSTMLLPLTPMLSIL 346
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-345 9.44e-97

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 290.72  E-value: 9.44e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427   1 MNPQANSIFITSLLLGTTITISSNHWIMAWMGLEINTLAILPLISKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWY 80
Cdd:MTH00200   1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427  81 TGQWDITQLTHPTSCLILTSAVAMKLGLVPFHFWFPEVLQGSPLTTGLLLSTLMKLPPITLLYMTSPSLNPTLLTTLAIL 160
Cdd:MTH00200  81 SGQWGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427 161 SAALGGWMGLNQTQVRKILAFSSISHLGWMAIVIIYNPKLTLLNFYLYTMMTAAVFLTLNTIKVSKLSTLMTTWTKIPSL 240
Cdd:MTH00200 161 SVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPIL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427 241 NTMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATLISLLSLLSLFFYLRLAYCTAITLPPHTTNHMKQWRTNKP 320
Cdd:MTH00200 241 SMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWRTKSN 320

                        330       340
                 ....*....|....*....|....*
gi 219882427 321 TNITIAMLITMSIALLPISPMILTI 345
Cdd:MTH00200 321 SNLLVGLLLLLSILGLPLTPQLLFL 345
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 1-345 1.56e-76

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 239.06  E-value: 1.56e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427   1 MNPQANSIFITSLLLGTTITISSNHWIMAWMGLEINTLAILPLISKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWY 80
Cdd:MTH00041   1 MNRNVLIFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427  81 TGQWDITQLTHPTSCLILTSAVAMKLGLVPFHFWFPEVLQGSPLTTGLLLSTLMKLPPITLLYMTSPSLNPTLLTTLAIL 160
Cdd:MTH00041  81 SGSWSINGPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427 161 SAALGGWMGLNQTQVRKILAFSSISHLGWMAIVIIYNPKLTLLNFYLYTMMTAAVFLTLNTIKVSKLSTLMTTWTKIPSL 240
Cdd:MTH00041 161 SVLVGGWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPIS 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427 241 NTMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATLISLLSLLSLFFYLRLAYCTAITLPPHTTNHMKQWRTNKP 320
Cdd:MTH00041 241 AFLFILSILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHSISLFSWRNSGN 320

                        330       340
                 ....*....|....*....|....*...
gi 219882427 321 TNIT---IAMLITMSIALLPISPMILTI 345
Cdd:MTH00041 321 ITVYgviLSILSSISILGLLLIPLFLSF 348
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-345 6.19e-53

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 177.71  E-value: 6.19e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427   1 MNPQANSIFITSLLLGTTITISSNHWIMAWMGLEINTLAILPLISKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWy 80
Cdd:MTH00160   2 MMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML- 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427  81 tgqwdITQLTHPTSCLILTSAVAMKLGLVPFHFWFPEVLQGSPLTTGLLLSTLMKLPPITLLYMTspsLNPTLLTTLAIL 160
Cdd:MTH00160  81 -----NLMLFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYL---INNNFIIIIIIL 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427 161 SAALGGWMGLNQTQVRKILAFSSISHLGWMAIVIIYNPKLTLLNFYLYTMMTAAVFLTLNTIKVSKLSTLMTTWTKIPSL 240
Cdd:MTH00160 153 SAIIGAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKI 232

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427 241 NTMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATLISLLSLLSLFFYLRLAYcTAITLPPHTTNHMKQWRTNKp 320
Cdd:MTH00160 233 KFLLFLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISY-SSLMLNYNKNKWNLKKKKNK- 310

                        330       340
                 ....*....|....*....|....*
gi 219882427 321 TNITIAMLITMSIALLPISPMILTI 345
Cdd:MTH00160 311 FSLILNFLSFISLFGLILSSLLFLL 335
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 5-298 6.69e-44

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 153.89  E-value: 6.69e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427   5 ANSIFITSLLLGTTITISSNHWIMAWMGLEINTLAILPLISKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWYTGQW 84
Cdd:MTH00144   5 SNLLFLFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSW 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427  85 DITqlthptscLILTSAVAMKLGLVPFHFWFPEVLQGSPLTTGLLLSTLMKLPPITLLYMTSPSLNP-TLLTTLAILSAA 163
Cdd:MTH00144  85 FSM--------SLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWLaYLLCVISVLSAL 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427 164 LGGWMGLNQTQVRKILAFSSISHLGWMAIVIIYNPKLTLLNFYLYTMMTAAVFLTLNTiKVSKLSTLMTTWTKIPSLNTM 243
Cdd:MTH00144 157 VGSIGGLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWS-GDSGSMKDLGSLKPSYKTGLS 235

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 219882427 244 LLLTLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATLISLLSLLSLFFYLRLAY 298
Cdd:MTH00144 236 IISLLLSLGGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFF 290
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 7-340 1.22e-41

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 148.00  E-value: 1.22e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427   7 SIFITSLLLGTTITISSNHWIMAWMGLEINTLAILPLISKSHHPRAIEAATKYFLTQAAASALVLFSSmtnawyTGQWDI 86
Cdd:MTH00011   9 FLFSSTMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGM------TMMWSF 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427  87 TQLTHPTSCLILTSAVAMKLGLVPFHFWFPEVLQGSPLTTGLLLSTLMKLPPITLLYMTSPSLNPTLLTTLAILSAALGG 166
Cdd:MTH00011  83 PSLLKNITALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAMSALAGG 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427 167 WMGLNQTQVRKILAFSSISHLGWMAIVIIYNPKLTLLNFYLYTMMTAAVFLTLNTIKVSKLSTLMTTWTKIPSLNTMLLL 246
Cdd:MTH00011 163 LGGMNQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLFI 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427 247 TLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATLISLLSLLSLFFYLRLAYcTAITLPPHTTNhmkqwRTNKPTNITIA 326
Cdd:MTH00011 243 MLLSLGGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIF-NFMYLSPTFSS-----LKSAPYEPKTK 316

                        330
                 ....*....|....
gi 219882427 327 MLITMSIALLPISP 340
Cdd:MTH00011 317 ILISMCTLSLGLIP 330
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 7-342 2.14e-36

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 133.64  E-value: 2.14e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427   7 SIFITSLLLGTTITISSNHWIMAWMGLEINTLAILPLISKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAwytgqwdI 86
Cdd:MTH00197   1 FLFLFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSLSF-------S 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427  87 TQLTHPTSCLILTSAVAMKLGLVPFHFWFPEVLQGSPLTTGLLLSTLMKLPPITLLymTSPSLNPTLLTTLAILSAALGG 166
Cdd:MTH00197  74 NLYLSLLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLIL--AFNSSSFMGLLICSVLSSLIGG 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427 167 WMGLNQTQVRKILAFSSISHLGWMAIVIIYNPKLTLLNFYLYTMMTAAVFLTLNTIKVSKLSTLMTTWTKIPSLNTMLLL 246
Cdd:MTH00197 152 IGGMNQSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGL 231

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427 247 TLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATLISLLSLLSLFFYLRLAYCTAItlppHTTNHMKQWRTNKPTNITIA 326
Cdd:MTH00197 232 SFLSLGGLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKSLI----LSNWMINFLMKINLLYSGLF 307

                        330
                 ....*....|....*.
gi 219882427 327 MLITMSIALLPISPMI 342
Cdd:MTH00197 308 ILLMMMLPLLMIFTMI 323
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-268 2.98e-24

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 100.47  E-value: 2.98e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427   23 SNHWIMAWMGLEINTLAILPLI-SKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWYTGQWDITQL-----------T 90
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELskaltgglnssG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427   91 HPTSCLILTSAVAMKLGLVPFHFWFPEVLQGSPLTTGLLLSTLMKLPPITLLYMTSPSLNPT------LLTTLAILSAAL 164
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAATLVKAGGYGLIRRSLLYLPSspfiqqILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427  165 GGWMGLNQTQVRKILAFSSISHLGWM----AIVIIYNPKLTLLNFYLYTMMTAAVFLTLNTIKVSKLST-----LMTTWT 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMlialGAGTIYGIQAAIFHLLTHGLFSAGLFLCAGSVIYRRVHTrnirdYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 219882427  236 KIPSLNTMLLLTLLSLAGLPPLTGFLPKWLIIQ 268
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 14-298 1.29e-21

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 95.18  E-value: 1.29e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427  14 LLGTTITISSNHWIMAWMGLEINTLAILPLIS-KSHHPRAIEAATKYFLTQAAASALVLF-SSMTNAwYTGQWDITQLTH 91
Cdd:COG1007  112 TLGMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgISLLYG-ATGSLNLAGIAA 190

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427  92 PTS------------CLILTSAVAMKLGLVPFHFWFPEVLQGSPlttglllstlmklPPIT-----------------LL 142
Cdd:COG1007  191 ALAagganspllllgLVLVLAGLAFKLSAVPFHMWTPDVYEGAP-------------TPVTaflatapkiaafaallrLL 257

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427 143 YMTSPSLNP---TLLTTLAILSAALGGWMGLNQTQVRKILAFSSISHLGWMAIVIIYNPKLTL--LNFYL--YTMMTAAV 215
Cdd:COG1007  258 VEAFPGLAAdwqLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLGVsaALFYLlaYLFMNLGA 337

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427 216 FLTLntIKVSKLSTLMTTWTKI-------PSLNTMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATLISLLSLL 288
Cdd:COG1007  338 FAVI--LLLSRKGGEAEEIEDLaglarrsPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVI 415

                        330
                 ....*....|
gi 219882427 289 SLFFYLRLAY 298
Cdd:COG1007  416 SAYYYLRVVK 425
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 13-267 1.76e-21

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 93.94  E-value: 1.76e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427  13 LLLGTTITISSNHWIMAWMGLEINTLAILPLI-SKSHHPRAIEAATKYFLTQAAASALVLFS-------------SMTNA 78
Cdd:MTH00196   2 VALGILCLISSSNWLSVYLAIELQTLSLFILIaQNRGSGYSAEAGLKYFVLGALSSGLFLFGcallcgttgglhlSYINL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427  79 WYTGQWDITQLTHPTSCLILTSAVAMKLGLVPFHFWFPEVLQGSPLTTGLLLSTLMKLPPITLLYMTSPSLNptLLTTLA 158
Cdd:MTH00196  82 VLNSGQSFSSVSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNVN--ILLIGG 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427 159 ILSAALGGWMGLNQTQVRKILAFSSISHLGWMAIVI----IYNPKLTLLNFYLYTMMTAAVFLTLNTIKVSK--LSTLMT 232
Cdd:MTH00196 160 LFSLFVGAIGALNQTKIKRLLAYSGIGHMGFVLWGIeigsFESIQASLVYLFIYIIMSICVFSIILALNVYKnlIIEFSG 239

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 219882427 233 TWTKIPSLNTMLLLTLLSLAGLPPLTGFLPKWLII 267
Cdd:MTH00196 240 LSRRLPILAITLALTFLSIAGIPPLVGFLGKWLIL 274
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
14-296 3.84e-21

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 93.73  E-value: 3.84e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427  14 LLGTTITISSNHWIMAWMGLEINTLAILPLIS-KSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWYTGQWDITQLTHP 92
Cdd:PRK05777 113 LLGMMVMVSANDLLTLFLGLELLSLPLYALAAlRRDRRRSLEAAIKYFVLGALASGFLLYGMSLLYGATGSLSFAGIAKA 192

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427  93 TS------------CLILTSAVAMKLGLVPFHFWFPEVLQGSPLTTGLLLSTLMKL----PPITLLYMTSPSLNPT---L 153
Cdd:PRK05777 193 LAdgsgnsllllfgLVFLLVGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIaafaVLLRLLVVAFGGLSEDwqqV 272

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427 154 LTTLAILSAALGGWMGLNQTQVRKILAFSSISHLGWMAIVIIYNPKLTL--LNFYL--YTMMTAAVFLTLNTIK------ 223
Cdd:PRK05777 273 LAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLAAGTAEGYsaVLFYLlaYLFMTLGAFGVISLLRrkggea 352

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 219882427 224 --VSKLSTLMttWTKiPSLNTMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATLISLLSLLSLFFYLRL 296
Cdd:PRK05777 353 esISDFAGLS--KRS-PLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFYYLRV 424
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 4-267 2.10e-19

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 88.92  E-value: 2.10e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427   4 QANSIFITSLLLGTTITISSNHWIMAWMGLEINTLAILPLIS-KSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWYTG 82
Cdd:MTH00199  97 QSSPILILIVALGSLLLVSSINWLSIYLAIELQTLTLFILVAlKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTG 176

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427  83 QWDI----TQLTHPTSCLILTSAVAMKLGLVPFHFWFPEVLQGSPLTTGLLLSTLMKLPPITLLYMTSPSLNPTLLTtlA 158
Cdd:MTH00199 177 ETSIqginSILTGDVGKILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNVVLIC--A 254

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427 159 ILSAALGGWMGLNQTQVRKILAFSSISHLGW----MAIVIIYNPKLTLLNFYLYTMMTAAVFLTLNTIKVSK--LSTLMT 232
Cdd:MTH00199 255 VLSIIYGAIGALNQTKIKRLLAYSGIGHMGFilfgVAIGSFESIQASLIYMIIYVIMSICSFSIILSLKLTKglIVEVSG 334

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 219882427 233 TWTKIPSLNTMLLLTLLSLAGLPPLTGFLPKWLII 267
Cdd:MTH00199 335 LSRKNPVIALTLALTFLSIAGIPPLAGFLSKWLIL 369
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 14-297 2.90e-19

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 88.47  E-value: 2.90e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427   14 LLGTTITISSNHWIMAWMGLEINTLAILPLIS-KSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWYTGQWDITQLTHP 92
Cdd:TIGR01770 112 LLGIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLLF 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427   93 TSCLILT------------SAVAMKLGLVPFHFWFPEVLQGSPLTTGLLLSTLMKLP---PITLLYMTSPS----LNPTL 153
Cdd:TIGR01770 192 LSNGMLNisllllgivlilVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAifaVFLRLFLYILFgfseAWQIF 271

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427  154 LTTLAILSAALGGWMGLNQTQVRKILAFSSISHLGWMAIVIIYNPKLTLLN--FYL--YTMMTAAVFLTLNTIKVSK--- 226
Cdd:TIGR01770 272 LAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAvlFYIfiYALMSLGAFGVLSLLRSYKdew 351

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 219882427  227 ---LSTLMTTWTKIPSLNTMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATLISLLSLLSLFFYLRLA 297
Cdd:TIGR01770 352 ieyISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVV 425
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 15-267 5.86e-14

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 72.58  E-value: 5.86e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427  15 LGTTITISSNHWIMAWMGLEINTLAILPLISKSHHPRAI---------EAATKYFLTQAAASALVLFSSMTNAWYTGQ-- 83
Cdd:MTH00198 199 LGGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFGCALYFGFTGNeg 278

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427  84 --WDITQLTHPTS----------CLILTSAVAMKLGLVPFHFWFPEVLQGSPLTTGLLLSTLMKLPPITLLymTSPSLNP 151
Cdd:MTH00198 279 mlGTILSATLETTnielrqgslgYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILL--TSLVITS 356

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427 152 TLLTTLAILSAALGGWMGLNQTQVRKILAFSSISHLGWMAIVIIYNPKLTLLNFYLYTMM----TAAVFLTLNTIK---- 223
Cdd:MTH00198 357 KLLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFILIGVSAGTYESLQASWTYAVTylvsALASFTVICTLEefgt 436

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 219882427 224 -----------------VSKLSTLMTTWTKIPSLNTMLLLTLLSLAGLPPLTGFLPKWLII 267
Cdd:MTH00198 437 rtptsrqrdgsfgnynlVRRLVDLTILSRGQPYIAFSLAIVFLSLAGIPPLLGFLGKWFIL 497
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 13-279 1.77e-12

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 67.86  E-value: 1.77e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427  13 LLLGTTITISSNHWIMAWMGLEINTLAILPLISKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWYTGQWDITQLTH- 91
Cdd:COG0651  116 LLAGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNMADLAAr 195

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427  92 ---------PTSCLILTSAVAMKLGLVPFHFWFPEVLQGSPLTTGLLLSTLM-KLPP------ITLLYMTSPSLNP-TLL 154
Cdd:COG0651  196 laeldpgllLAAFALLLVGFGIKAALFPLHFWLPDAYPAAPSPVSALLSGLLtKVGVyailrvLTLLFGADPALFLgTLL 275

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427 155 TTLAILSAALGGWMGLNQTQVRKILAFSSISHLGWMAIVIIYNPKLTLLNFYLY----TMMTAAVFLT-------LNTIK 223
Cdd:COG0651  276 LVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHllnhALAKALLFLAagaieraTGTRD 355

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 219882427 224 VSKLSTLmttWTKIPSLNTMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAA 279
Cdd:COG0651  356 LDKLGGL---GKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLA 408
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
50-195 1.88e-11

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 65.07  E-value: 1.88e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427  50 PRAIEAATKYFLTQAAASALVLF-SSMTNAWYTGQwdiTQL--------THPTSCLILT-----SAVAMKLGLVPFHFWF 115
Cdd:PRK02504 157 PRSNEAALKYLLIGAASSAIFLYgSSLLYGLSGGS---TQLsaialaliTSPSLGLALAlvfviAGIAFKISAVPFHQWT 233

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427 116 PEVLQGSPLTTGLLLSTLMKLP----PITLLYMTSPSLNP---TLLTTLAILSAALGGWMGLNQTQVRKILAFSSISHLG 188
Cdd:PRK02504 234 PDVYEGSPTPVVAFLSVGSKAAgfalAIRLLVTAFPSFDEqwkLLFTALAILSMVLGNVVALAQTSMKRMLAYSSIGQAG 313


                 ....*..
gi 219882427 189 WMAIVII 195
Cdd:PRK02504 314 FVMIGLV 320
ndhB CHL00049
NADH dehydrogenase subunit 2
 8-208 3.31e-11

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 64.25  E-value: 3.31e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427   8 IFITSLLLGTTITISSNHWIMAWMGLEINTLAILPLISKSHHP-RAIEAATKYFLTQAAASALVL--FSsmtnaWYTGQ- 83
Cdd:CHL00049 115 LFVLTATLGGMFLCGANDLITIFVALECLSLCSYLLSGYTKKDvRSNEATMKYLLMGGASSSILVygFS-----WLYGLs 189

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427  84 ------WDI------TQLTHPTSCLI----LTSAVAMKLGLVPFHFWFPEVLQGSPLTTGLLLSTLMKLPPITL----LY 143
Cdd:CHL00049 190 ggeielQEIvnglinTQMYNSPGISIalifITVGIGFKLSLAPFHQWTPDVYEGSPTPVVAFLSVTSKVAASALatriFD 269

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 219882427 144 MTSPSLNP---TLLTTLAILSAALGGWMGLNQTQVRKILAFSSISHLGWMAIVII-------YNPKLTLLNFYLY 208
Cdd:CHL00049 270 IPFYFSSNewhLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIvgdsndgYASMITYMLFYIF 344
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-266 1.13e-08

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 56.26  E-value: 1.13e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427  33 LEINTLAILPLIS-KSHHPRAIEAATKYFLTQAAASALVLFS---------SMTNAWYTGQWDITQLTHPTSCL-ILTSA 101
Cdd:PRK08376 150 LEIMSIASYALVAfRNDTWEAIEAGIKYMFVGSLASSMVLLGiallygqygTLNMAYLAVKMSENPTVVAKIALaLFIAG 229

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427 102 VAMKLGLVPFHFWFPEVLQGSPLTTGLLLSTLmKLPPITLLY-----MTSPSLNPT----LLTTLAILSAALGGWMGLNQ 172
Cdd:PRK08376 230 LAMKSGAVPVHMWLPDAYPAAPSSISAMLLVI-KQAGLYALArvlfsIYGPAINLAtvgwVIIILGCLTMFVGVAMAVVQ 308

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427 173 TQVRKILAFSSISHLGWM------AIVIIYNPKLT----------LLNFYLYTMMTAAVFLT-------LNTIKVSKLST 229
Cdd:PRK08376 309 KDVKRLLAYHSVSQIGYMllglgvGLAALGDPAMAsygeialaggIYHIVNHALYKALLFLTagaviyeTGTRNLNELGG 388

                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 219882427 230 LMTTwtkIPSLNTMLLLTLLSLAGLPPLTGFLPKWLI 266
Cdd:PRK08376 389 LART---MPKTTIAFLIGAAAIVGLPPFNGFASKWLI 422
NADH_dehy_S2_C pfam06444
NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region ...
 291-340 2.24e-08

NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region specific to the eukaryotic NADH dehydrogenase subunit 2 protein and is found in conjunction with pfam00361.


Pssm-ID: 461914 [Multi-domain]  Cd Length: 51  Bit Score: 49.95  E-value: 2.24e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 219882427  291 FFYLRLAYCTAITLPPHTTNHMKQWRTNKPTNIT-IAMLITMSIALLPISP 340
Cdd:pfam06444   1 FFYLRLSYSTTLTLFPNTNNSKMKWRFNSTKNTLlLPTLTTLSILLLPLTP 51
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 49-194 9.07e-08

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 53.55  E-value: 9.07e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427  49 HPRAIEAATKYFLTQAAASALVLFSSMTNAWYTGQW--DITQLTH-----PTSCLILTS---AVAMKLGLVPFHFWFPEV 118
Cdd:COG1008  156 GERRIYAAIKFFLYTLAGSLLMLVAILALYFLAGALtfDIAELAAaplplTAQLLLFLAffiAFAVKVPMFPFHTWLPDA 235

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427 119 LQGSPLTTGLLLSTLM-KLP-------PITLLYMTSPSLNPTLLTtLAILSAALGGWMGLNQTQVRKILAFSSISHLGWM 190
Cdd:COG1008  236 HVEAPTAGSVLLAGVLlKMGgygllrfALPLFPEASAYFAPLLAA-LGVIGIIYGALVALAQTDLKRLIAYSSVSHMGFV 314


                 ....
gi 219882427 191 AIVI 194
Cdd:COG1008  315 LLGI 318
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 50-194 1.19e-05

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 46.86  E-value: 1.19e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427   50 PRAIEAATKYFLTQAAASALVLFSSMTNAWYTGQW----DITQLTHPTSC-----LILTSAVAMKLGLVPFHFWFPEV-L 119
Cdd:TIGR01972 152 PNRIYAAMKFFLYTLAGSLLMLLAILGLYFLGGGTfdllELLNLPLPFGVqtwlfLAFFIAFAVKVPLFPLHTWLPDAhV 231

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427  120 QGSPLTTGLLLSTLMKLPP-------ITLLYMTSPSLNPtLLTTLAILSAALGGWMGLNQTQVRKILAFSSISHLGWMAI 192
Cdd:TIGR01972 232 EAPTAGSVILAGVLLKMGTygflrfnLPLFPDASLYFAP-VLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVLL 310


                  ..
gi 219882427  193 VI 194
Cdd:TIGR01972 311 GI 312
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 2-275 1.27e-05

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 46.91  E-value: 1.27e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427   2 NPQANSIFITSLLLGTTITISSNHWIMAWMGLEINTLAILPLISKSHHpRAIEAATKYFLTQAAASALVLFSSMTNAWYT 81
Cdd:PRK08668  96 NDAYFNMFALMSLAGVLGVFLANDLLTLYIFWEIMTFSSFMMVPMGKK-ESRKASLKYFVLSAIGAYAMLYAIFLIYAKT 174

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427  82 GQWDIT-------QLTHPTSCLI----LTSAVAMKLGLVPFHFWFPEVLQGSP------------------LTTGLLLST 132
Cdd:PRK08668 175 GTFDFAdisqgliNDTSTGFALIvflfLLAFGVAKAGIFPLHVWAPDAYSEAPqsfsavlsgqlsklgaygFLLVLYVLP 254

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427 133 LMKLPPITLLYMTSPSLNpTLLTTLAILSAALGGWMGLNQTQVRKILAFSSISHLGWMAIVIIYNPKLT----LLNFYLY 208
Cdd:PRK08668 255 GTKLFSEFGTYRGVPLFN-YILAWLGNISIIVGTLMAILQEDIKKLIAYSSVANGGYILVGLGLGTSLGfaggLFHVFNH 333

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 219882427 209 TMMTAAVFLTLNTI----KVSKLSTLMTTWTKIPSLNTMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQDM 275
Cdd:PRK08668 334 ALFKGLFFLIFAAViyrtGTTKISEMGGLIEKMPFTFAMYLVAIISLAGIPPMSGFASKWLIFEALISKGM 404
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 13-194 1.73e-05

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 46.29  E-value: 1.73e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427  13 LLLGTTITISSNHWIMAWMGLEINTLAILPLISKSHHPRAIEAATKYFLTQAAA------SALVLFSSMTNAWYTGQWDI 86
Cdd:PRK08676 111 LLSVITFAFFSDNLALFWIFAELTTVFSAMLIAILSARENIDAALKYIFIASTAmifafiGLIFLFSLTRQALGTGTLNW 190

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427  87 TQLTHPTSCL----ILTSAVAM------KLGLVPFHFWFPEVLQGSPLTTGLLLSTLMKLPPITLLYMTSPSLNPT---- 152
Cdd:PRK08676 191 TELAAHASLLspsvLGASFLFIfigflaKSGLVPFHTWLPAAYAKAPSVVSALLSGTVLNIGIYGILRLSALLRQSgaae 270

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 219882427 153 ----LLTTLAILSAALGGWMGLNQTQVRKILAFSSISHLGWMAIVI 194
Cdd:PRK08676 271 qfsnVLIGLGIFSIAVAAFSMLSQRNLKKLIAFSSIEHMGLMLLGI 316
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 7-194 3.35e-05

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 45.53  E-value: 3.35e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427   7 SIFITSLLLgttITISSNHWIMaWMGLEINTLAILPLISKSHH-PRAIEAATKYFLTQAAASALVLFSSMTNAWYTGQWD 85
Cdd:COG1009  118 LLFMAAMLG---LVLSDNLLLL-FVFWELVGLCSYLLIGFWYEkPSARRAARKAFLVTRVGDLGLLLGILLLGAIAGTLN 193

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427  86 ITQL-----THPTSCLILTSAVAM------KLGLVPFHFWFPEVLQGsPLttglllstlmklPPITLL----------YM 144
Cdd:COG1009  194 FSELlaaapTILSSPLLTLILLLLllgafgKSAQFPLHFWLPDAMEG-PT------------PVSALLhaatmvkagvYL 260

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 219882427 145 ---TSP--SLNPTLLTTLAILSAA---LGGWMGLNQTQVRKILAFSSISHLGWMAIVI 194
Cdd:COG1009  261 larLSPlfALSPVWLTVVAIIGAItalFAALIALAQTDIKRVLAYSTVSQLGYMFLAL 318
PRK12644 PRK12644
putative monovalent cation/H+ antiporter subunit A; Reviewed
 96-263 3.48e-05

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237154 [Multi-domain]  Cd Length: 965  Bit Score: 45.69  E-value: 3.48e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427  96 LILTSAVAmKLGLVPFHFWFPEVLQGSPLTTGLLLSTLMKLPPITLL------YMTSPSLNPTLLtTLAILSAALGGWMG 169
Cdd:PRK12644 208 LILVGALS-KSAIVPFHFWLPGAMAAPTPVSAYLHAAAMVKAGIYLVarlapgFADVPVWRPTVL-VLGLATMLLGGWRA 285

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427 170 LNQTQVRKILAFSSISHLGWMAIVIIYNPK------LTLLnfYLYTMMTAAVFLTLNTIKVS-------KLSTLmttWTK 236
Cdd:PRK12644 286 LRQHDLKLILAYGTVSQLGFLTVLVGIGTRdaalagLAML--LAHALFKAALFLVVGIIDHStgtrdirKLSGL---GRR 360

                        170       180
                 ....*....|....*....|....*..
gi 219882427 237 IPSLNTMLLLTLLSLAGLPPLTGFLPK 263
Cdd:PRK12644 361 QPVLAVVAALAAASMAGLPPLLGFVAK 387
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-336 2.19e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 42.94  E-value: 2.19e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427  33 LEINTLAILPLISKSHHPRAIEAATKYFLTQAAASALVLFS-SMTNAwYTGQWDITQL--------THPTSCLILTSAVA 103
Cdd:PRK08375 135 LEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGvGLLYG-VTGTLNMADLagalaenpTVVTAFGFVLLALA 213

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427 104 MKLGLVPFHFWFPEVLQGSPlttglllstlmklPPITLL------------------------YMTSPSLNpTLLTTLAI 159
Cdd:PRK08375 214 LKAAVFPLHTWLPRAYPAAP-------------PVVTALlsglvtkvavyaliriyftvfggdFRFALGLG-WLLAVLAL 279

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427 160 LSAALGGWMGLNQTQVRKILAFSSISHLGWMAIVIIYNPKLTLLNFYLYT-----------MMTAAVFLTLNTIKVSKLS 228
Cdd:PRK08375 280 LSMLVGSLAALGQDDVKRVLAYSTVSQMGYILLGLALLTPLALAAGLLHLlhhalmkgalfLAAGAIEVTYGTRRLSELS 359

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427 229 TLMTtwtKIPSLNTMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATLISLLSLLSLFFYLRLAYcTAITLPPht 308
Cdd:PRK08375 360 GLGR---RMPLTAAAFAVASLSLIGVPPTSGFVSKWYLVVGAVEAGQWLVLAVLLASSLLALLYFLRIWY-RAFFGPP-- 433

                        330       340
                 ....*....|....*....|....*...
gi 219882427 309 TNHMKQWRTNKPTNITIAMLITMSIALL 336
Cdd:PRK08375 434 PPGSEAPKQEAPLGMLAPSLALALLSLL 461
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
55-203 3.52e-04

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 42.38  E-value: 3.52e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427  55 AATKYFLTQAAASALVLFSSMTNAWYTG-------QWDITQLTHPTSCLILTS---AVAMKLGLVPFHFWFPEV-LQGSP 123
Cdd:PRK06473 158 AATKFLLYTAISGILILVSFLGLVWLSGassfdyePLRSHTLPLSTQLLLLAPilvGFGIKIPLVPFHTWLPDAhVEAST 237

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427 124 LTTGLLLSTLMKLPPITLL------YMTSPSLNPTLLTTLAILSAALGGWMGLNQTQVRKILAFSSISHLGWMAIVIIYN 197
Cdd:PRK06473 238 PVSVLLAGVLLKLGTYGLLrfgvglFPEAWVYLAPWLATWAVVSVLYGASCAIAQKDMKKMVAYSSIGHMGYILLAAAAA 317


                 ....*.
gi 219882427 198 PKLTLL 203
Cdd:PRK06473 318 TPLSIL 323
PRK12650 PRK12650
DUF4040 family protein;
98-194 5.73e-04

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 41.95  E-value: 5.73e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427  98 LTSAVAM--------KLGLVPFHFWFPEVLQGSPLTTGLLLSTLMKLPPITLLYMTSPSL--NPT---LLTTLAILSAAL 164
Cdd:PRK12650 206 LTTVVAVliavaaftKSAQFPFHFWLPEAMAAITPVSAFLHAAAVVKAGIYLLLRFSPVFhdVAVwnwLLIIVGMITALM 285

                         90       100       110
                 ....*....|....*....|....*....|
gi 219882427 165 GGWMGLNQTQVRKILAFSSISHLGWMAIVI 194
Cdd:PRK12650 286 GAVFAVQKTDLKKLTAYSTVSQLGWIVATI 315
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 55-194 1.10e-03

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 40.79  E-value: 1.10e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427  55 AATKYFLTQAAASALVLFSSMTNAWYTGQ--WDITQLTH---PTSCLILTS-----AVAMKLGLVPFHFWFPEVL-QGSP 123
Cdd:PRK12561 138 AATKFILYTALASIFILVAGLALALSGDTftFDLAELGAksyPLALELLLYagfliAFGVKLPIFPLHTWLPDAHgEASA 217

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 219882427 124 LTTGLLLSTLMKLPPITLLYMTSPSLNPT------LLTTLAILSAALGGWMGLNQTQVRKILAFSSISHLGWMAIVI 194
Cdd:PRK12561 218 PVSMILAGVLLKMGGYALIRFNVQMLPDAhvyfapALAILGVVNIIYGALNAFAQDNVKRRLAYSSVSHMGFVLLGI 294
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 6-192 1.20e-03

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 40.68  E-value: 1.20e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427   6 NSIFITSLLLgttiTISSNHWIMAWMGLEINTLAILPLISKSHHPRAIEAATKYFLTQAAASALVLFSS----------M 75
Cdd:PRK06458 114 YQLFLFTMLL----ALTSNNLGLMWVAIEATTLSSALLVGIYRTRASLEAAWKYIIICSVGVAFALFGTilvyanaatvM 189

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427  76 TNAWYTGQW-DITQLTHPTSCLILTSAVAM-------KLGLVPFHFWFPE-----------VLQGSPLTTGLLLSTLMKl 136
Cdd:PRK06458 190 GDGEMAILWtELLKHASLLDPTLMKLAFVFlligfgtKVGLFPMHAWLPDahseapspvsaLLSGVLLNVALYAVLRYY- 268

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 219882427 137 ppITLLYMTSPSLNPTLLTTLAILSAALGGWMGLNQTQVRKILAFSSISHLGWMAI 192
Cdd:PRK06458 269 --ILIDAAIGSDFPGRLLLIFGLLSVLVAAFFLLRQRDIKRLFAYSSIEHMGLIAF 322
ND5 MTH00032
NADH dehydrogenase subunit 5; Provisional
 105-271 2.94e-03

NADH dehydrogenase subunit 5; Provisional


Pssm-ID: 214407 [Multi-domain]  Cd Length: 669  Bit Score: 39.56  E-value: 2.94e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427 105 KLGLvpfHFWFPEVLQGSPLTTGLLLSTLMKLPPITLLYMTSPSLNPTLLTTLAI-----LSAALGGWMGLNQTQVRKIL 179
Cdd:MTH00032 241 QLGL---HTWLPDAMEGPTPVSALIHAATMVTAGVFLMIRSFPLFEKAPLTLLIItifgaLTAFFAATVGLVQNDLKKVI 317

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427 180 AFSSISHLGWMAIVIIY--NPKLTLLNFYLYTMMTAAVFLTLNTI---------KVSKLSTLMTTwtkIPSLNTMLLLTL 248
Cdd:MTH00032 318 AYSTCSQLGYMVLIIGIegSHNVGLFHLVNHAFFKALLFLSAGSVihsttvdeqDMRKMGGLIHS---IPFTYTMMLIGS 394

                        170       180
                 ....*....|....*....|...
gi 219882427 249 LSLAGLPPLTGFLPKWLIIqELT 271
Cdd:MTH00032 395 FSIMGLPYLTGFYSKDLIL-ELT 416
PRK12662 PRK12662
putative monovalent cation/H+ antiporter subunit D; Reviewed
 142-267 4.15e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 183662 [Multi-domain]  Cd Length: 492  Bit Score: 38.95  E-value: 4.15e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427 142 LYMTSPSLNpTLLTTLAILSAALGGWMGLNQTQVRKILAFSSISHLGWMAIVIIYNPKLTLLNFYLY----TMMTAAVFL 217
Cdd:PRK12662 271 FVFTTLPFN-NVFMILAALAIVFGSVLAILSKDIKRIFAYSSISHIGYIILAVSLNTYYGLAAAVAYivnhSIVKSALFM 349

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 219882427 218 TLNTIK----VSKLSTLMTTWTKIPSLNTMLLLTLLSLAGLPPLTGFLPKWLII 267
Cdd:PRK12662 350 VSGSISyhfgTTKLEDCLNLWKSMPKITLAFVLLSLSLIGMPPTSGFVAKWYIL 403
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 50-194 5.00e-03

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 38.64  E-value: 5.00e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427  50 PRAIEAATKYFLTQAAASALVLFSSMTNAWY----TGQWDITQLTH---PTSCLILT-----SAVAMKLGLVPFHFWFPE 117
Cdd:PRK05846 157 KNRIYAATKFFLYTLLGSLLMLVAIIYLVVVyynaTGTFDIADLLNlplPPGVQYWLflaffIAFAVKMPMFPLHTWLPD 236

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219882427 118 VLQGSPLTTGLLLSTLM-KLPPITLLYMTSPsLNP-------TLLTTLAILSAALGGWMGLNQTQVRKILAFSSISHLGW 189
Cdd:PRK05846 237 AHVQAPTAGSVLLAGILlKMGAYGLLRFSLP-LFPdashefaPIIITLGVIAIIYGALVALAQTDIKKLIAYSSISHMGF 315


                 ....*
gi 219882427 190 MAIVI 194
Cdd:PRK05846 316 VTLGI 320
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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