|
Name |
Accession |
Description |
Interval |
E-value |
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
460-845 |
6.42e-79 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 259.35 E-value: 6.42e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 460 MFNEEMRLAAWNRNLQEILDLPDSFFTEPRTYRDYIAYLIKHGEFGDVDLDAELQRQVEHADRQRRIERTRPDGRVLEIR 539
Cdd:COG4191 7 LLLLLLALLRALALALALLLLLLLLLLALLLLLLALLLALLALLLLLLLLLLLLLLELLLLLLALLGGLLRLLLLLGLLL 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 540 VNPVPGGGFVAIYSDITERKKAEERVRAARDAAEAALRELKAAQNRLVQAEKLASLGQLTAGIAHEIKNPLNFVNNFSAV 619
Cdd:COG4191 87 LLLLEALLLLLLAALDAEENAELEELERDITELERAEEELRELQEQLVQSEKLAALGELAAGIAHEINNPLAAILGNAEL 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 620 SVELIDELREAlagahldgklqteigeiaDMLQGNLDKVVQHGKRADSIVKNMLLHSRQGSGDHRPIDINALVEESLNLA 699
Cdd:COG4191 167 LRRRLEDEPDP------------------EELREALERILEGAERAAEIVRSLRAFSRRDEEEREPVDLNELIDEALELL 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 700 YHGARAEkpgfNITLERCFDQAAGEVDLFPQEITRVLLNLISNGfyaatkrkADANGGSYEPTLAATTKNLGDSVEIKIR 779
Cdd:COG4191 229 RPRLKAR----GIEVELDLPPDLPPVLGDPGQLEQVLLNLLINA--------IDAMEEGEGGRITISTRREGDYVVISVR 296
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 260177206 780 DNGTGIPPEVKEKMFNPFFTTKPAGEGTGLGLSLSHDiIVKQHAGSIEVDTKPGEFTEFRIVLPRS 845
Cdd:COG4191 297 DNGPGIPPEVLERIFEPFFTTKPVGKGTGLGLSISYG-IVEKHGGRIEVESEPGGGTTFTITLPLA 361
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
345-848 |
1.01e-73 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 247.57 E-value: 1.01e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 345 LGVVALSLISSVLIVWLYVGRNIVARLMNLSGIMTAIAGGSRSVAVPVAGTDEIGAMGRAVeifrrNAVdldhllaerae 424
Cdd:COG5000 11 LLLIALLLLLLALWLALLLARRLTRPLRRLAEATRAVAAGDLSVRLPVTGDDEIGELARAF-----NRM----------- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 425 aatrLERLvEERTRELAHRQAELRVTFDNMGDGVVMFNEEMRLAAWNRNLQEILDLPDSFFtEPRTYRDYiaylikhgeF 504
Cdd:COG5000 75 ----TDQL-KEQREELEERRRYLETILENLPAGVIVLDADGRITLANPAAERLLGIPLEEL-IGKPLEEL---------L 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 505 GDVDLDAELQRQVEHaDRQRRIERTRPDGRVLEIRVNPVPGGGFVAIYSDITErkkaeervraardaaeaalrelkaaqn 584
Cdd:COG5000 140 PELDLAELLREALER-GWQEEIELTRDGRRTLLVRASPLRDDGYVIVFDDITE--------------------------- 191
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 585 rLVQAEKLASLGQLTAGIAHEIKNPLNFVNnfsavsvelidelreaLAGAHLDGKLQTEIGEIADMLQGNLDKVVQHGKR 664
Cdd:COG5000 192 -LLRAERLAAWGELARRIAHEIKNPLTPIQ----------------LSAERLRRKLADKLEEDREDLERALDTIIRQVDR 254
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 665 ADSIVKNMLLHSRQGSGDHRPIDINALVEESLNLaYHGARAEKpgfNITLERCFDQAAGEVDLFPQEITRVLLNLISNGF 744
Cdd:COG5000 255 LKRIVDEFLDFARLPEPQLEPVDLNELLREVLAL-YEPALKEK---DIRLELDLDPDLPEVLADRDQLEQVLINLLKNAI 330
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 745 YAATKRkadanggsyePTLAATTKNLGDSVEIKIRDNGTGIPPEVKEKMFNPFFTTKPagEGTGLGLSLSHDIIvKQHAG 824
Cdd:COG5000 331 EAIEEG----------GEIEVSTRREDGRVRIEVSDNGPGIPEEVLERIFEPFFTTKP--KGTGLGLAIVKKIV-EEHGG 397
|
490 500
....*....|....*....|....
gi 260177206 825 SIEVDTKPGEFTEFRIVLPRSAAT 848
Cdd:COG5000 398 TIELESRPGGGTTFTIRLPLAEEA 421
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
439-848 |
1.27e-68 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 231.66 E-value: 1.27e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 439 ELAHRQAELRVTFDNMGDGVVMFNEEMRLAAWNRNLQEILDLP---------DSFFTEPRTYRDYIAYLIKHGefgdvdl 509
Cdd:COG3852 1 ALRESEELLRAILDSLPDAVIVLDADGRITYVNPAAERLLGLSaeellgrplAELFPEDSPLRELLERALAEG------- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 510 daelqrqveHADRQRRIERTRPDG--RVLEIRVNPVPG----GGFVAIYSDITERKKAEErvraardaaeaalrelkaaq 583
Cdd:COG3852 74 ---------QPVTEREVTLRRKDGeeRPVDVSVSPLRDaegeGGVLLVLRDITERKRLER-------------------- 124
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 584 nRLVQAEKLASLGQLTAGIAHEIKNPLNFVNNFsavsVELidelrealagahldgkLQTEIGEiaDMLQGNLDKVVQHGK 663
Cdd:COG3852 125 -ELRRAEKLAAVGELAAGLAHEIRNPLTGIRGA----AQL----------------LERELPD--DELREYTQLIIEEAD 181
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 664 RADSIVKNMLLHSRQGSGDHRPIDINALVEESLNLAyhgaRAEKPGfNITLERCFDQAAGEVDLFPQEITRVLLNLISNG 743
Cdd:COG3852 182 RLNNLVDRLLSFSRPRPPEREPVNLHEVLERVLELL----RAEAPK-NIRIVRDYDPSLPEVLGDPDQLIQVLLNLVRNA 256
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 744 FYAAtkrkadANGG------SYEPTLAATTKNLGDSVEIKIRDNGTGIPPEVKEKMFNPFFTTKPagEGTGLGLSLSHDI 817
Cdd:COG3852 257 AEAM------PEGGtitirtRVERQVTLGGLRPRLYVRIEVIDNGPGIPEEILDRIFEPFFTTKE--KGTGLGLAIVQKI 328
|
410 420 430
....*....|....*....|....*....|.
gi 260177206 818 IvKQHAGSIEVDTKPGEFTEFRIVLPRSAAT 848
Cdd:COG3852 329 V-EQHGGTIEVESEPGKGTTFRIYLPLEQAE 358
|
|
| KinC |
COG5807 |
Sporulation sensor histidine kinase C [Cell cycle control, cell division, chromosome ... |
451-844 |
3.53e-49 |
|
Sporulation sensor histidine kinase C [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444509 [Multi-domain] Cd Length: 358 Bit Score: 177.67 E-value: 3.53e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 451 FDNMGDGVVMFNEEMRLAAWNRNLQEILDLPDSffteprtyrDYIAYLIKHGEfgDVDLDAELQRQvEHADRQRrIERTR 530
Cdd:COG5807 33 FDSILEFVFFIDSKGEILECNDFAEDLYGLSQN---------EYIGKTFVEEK--CILKDEQLYNK-EAFDRIE-ISYLT 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 531 PDGRVLEIRV----NPVPGGGFVAIYSDITERKKAEErvraardaaeaalrelkaaqnRLVQAEKLASLGQLTAGIAHEI 606
Cdd:COG5807 100 KNGEFDEIIYpiyyKDGVILGLITVYRDITKRKEAED---------------------KLLRSEKLSVAGELAAGIAHEI 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 607 KNPLNFVNNFsavsVELIDELREALagahldgklqtEIGEIADMLQGNLDkvvqhgkRADSIVKNMLLHSRQGSGDHRPI 686
Cdd:COG5807 159 RNPLTSIKGF----LQLLQESREDS-----------EREEYFNIIISEID-------RINTIITELLVLSKPKKFNFKKL 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 687 DINALVEESLNLAYHGARAEkpgfNITLERCFDQAAGEVDLFPQEITRVLLNLISNGFYAATKrkadanGGSyeptLAAT 766
Cdd:COG5807 217 NLNDVLEDVIALLSTEAILK----NISIKYDLADDEPVINGDKNQLKQVFINLIKNAIEAMET------GGN----ITIK 282
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 260177206 767 TKNLGDSVEIKIRDNGTGIPPEVKEKMFNPFFTTKpaGEGTGLGLSLSHDIIvKQHAGSIEVDTKPGEFTEFRIVLPR 844
Cdd:COG5807 283 TYVEGDFVVISVKDEGIGIPEEVLEKIGEPFFTTK--EEGTGLGLSICKKII-EEHNGTIEVESKPGKGTTFTIYLPL 357
|
|
| PRK11360 |
PRK11360 |
two-component system sensor histidine kinase AtoS; |
452-844 |
2.22e-46 |
|
two-component system sensor histidine kinase AtoS;
Pssm-ID: 236901 [Multi-domain] Cd Length: 607 Bit Score: 175.93 E-value: 2.22e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 452 DNMGDGVVMFNEEMRLAAWNRNLQEILDLPDSFFTeprtYRDYIAYLIKHGEFGDVDLDAeLQRQVEHADRQrrIERTRP 531
Cdd:PRK11360 269 ESIADGVIAIDRQGKITTMNPAAEVITGLQRHELV----GKPYSELFPPNTPFASPLLDT-LEHGTEHVDLE--ISFPGR 341
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 532 DgRVLEIRV----------NPVpggGFVAIYSDITERKKAEErvraardaaeaalrelkaaqnRLVQAEKLASLGQLTAG 601
Cdd:PRK11360 342 D-RTIELSVstsllhnthgEMI---GALVIFSDLTERKRLQR---------------------RVARQERLAALGELVAG 396
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 602 IAHEIKNPLNFVNNFsavsVELIDElrealagaHLDGKLQTEIGEIadmlqgnldkVVQHGKRADSIVKNMLLHSRQGSG 681
Cdd:PRK11360 397 VAHEIRNPLTAIRGY----VQIWRQ--------QTSDPPSQEYLSV----------VLREVDRLNKVIDQLLEFSRPRES 454
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 682 DHRPIDINALVEESLNLAYHGARAEkpgfNITLERCFDQAAGEVDLFPQEITRVLLNLISNGFYAATKRKadanggsyep 761
Cdd:PRK11360 455 QWQPVSLNALVEEVLQLFQTAGVQA----RVDFETELDNELPPIWADPELLKQVLLNILINAVQAISARG---------- 520
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 762 TLAATTKNLGDS-VEIKIRDNGTGIPPEVKEKMFNPFFTTKPAgeGTGLGLSLSHDIIvKQHAGSIEVDTKPGEFTEFRI 840
Cdd:PRK11360 521 KIRIRTWQYSDGqVAVSIEDNGCGIDPELLKKIFDPFFTTKAK--GTGLGLALSQRII-NAHGGDIEVESEPGVGTTFTL 597
|
....
gi 260177206 841 VLPR 844
Cdd:PRK11360 598 YLPI 601
|
|
| COG4192 |
COG4192 |
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ... |
25-826 |
5.64e-46 |
|
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];
Pssm-ID: 443346 [Multi-domain] Cd Length: 640 Bit Score: 175.26 E-value: 5.64e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 25 AFAGISMFAVVAGLTGQYAFNEVRKALDRTKG-TIPPALAAVALARESEQVLAVGPRMLSARTDDEVKRRSMAASDGLVN 103
Cdd:COG4192 17 AFALSALLTLVASLVALFSWNSLSNQIRYILDdSLPKLQASLKLEENSNELVAALPEFAAATNTTERSQLRNQLNTQLAD 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 104 IGRLVDELRAtivDPLDTERLTSYVTNLRSNLSQFEVVASERVRAAIRREKLVNDTFAAYHEFRTAWGqhyAELQGNVLQ 183
Cdd:COG4192 97 IEELLAELEQ---LTQDAGDLRAAVADLRNLLQQLDSLLTQRIALRRRLQELLEQINWLHQDFNSELT---PLLQEASWQ 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 184 LRNKIDAASNSQERQAAINRFELAAdtleQIEREASVVFEFLTRAANTEDTGLLqsqaSDARNSVRALKGRIDDLERKL- 262
Cdd:COG4192 171 QTRLLDSVETTESLRNLQNELQLLL----RLLAIENQIVSLLREVAAARDQADV----DNLFDRLQYLKDELDRNLQALk 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 263 -AEGLIDPTQRLNS---IVTDVDGLFVTRTKEIEANRAGQRLLIANIALGDQLATVVEQLVDRARRDIDTATAQAYSVQT 338
Cdd:COG4192 243 nYPSTITLRQLIDEllaIGSGEGGLPSLRRDELAAQATLEALAEENNSILEQLRTQISGLVGNSREQLVALNQETAQLVQ 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 339 FGGAVQLGVVALSLISSVLIVWLYVGRNIVARLMNLSGIMTAIAGGSRSVAVPVAGTDEIGAMGRAVEIFRRNAvdldhl 418
Cdd:COG4192 323 QSGILLLAIALLSLLLAVLINYFYVRRRLVKRLNALSDAMAAIAAGDLDVPIPVDGNDEIGRIARLLRVFRDQA------ 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 419 laeraeaatrlerlvEERTRELAHRqaelrvtfdnmgdgvvmfneemrlaawnrnlqeildlpdsffteprtyrdyiayl 498
Cdd:COG4192 397 ---------------IEKTQELETE------------------------------------------------------- 406
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 499 ikhgefgdvdldaelqrqvehadrqrriertrpdgrvleirvnpvpgggfvaiysdITERKKAEErvraardaaeaalrE 578
Cdd:COG4192 407 --------------------------------------------------------IEERKRIEK--------------N 416
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 579 LKAAQNRLVQAEKLASLGQLTAGIAHEIKNPLNFVNN--FSAvsvelidelrealagahldgKLQTEiGEIADMLQGNLD 656
Cdd:COG4192 417 LRQTQDELIQAAKMAVVGQTMTSLAHELNQPLNAMSMylFSA--------------------KKALE-QENYAQLPTSLD 475
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 657 KVVQHGKRADSIVKNMLLHSRQGSGDHRPIDINALVEESLNLAYHGARAEKPGFNITLErcfDQAAGEVDLFPQeitrVL 736
Cdd:COG4192 476 KIEGLIERMDKIIKSLRQFSRKSDTPLQPVDLRQVIEQAWELVESRAKPQQITLHIPDD---LMVQGDQVLLEQ----VL 548
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 737 LNLISNGFYAATKRKadanggsyEPTLAATTKNlgDSVEIKIRDNGTGIPpeVKEKMFNPFFTTKPAGEGTGLGLSLShd 816
Cdd:COG4192 549 VNLLVNALDAVATQP--------QISVDLLSNA--ENLRVAISDNGNGWP--LVDKLFTPFTTTKEVGLGLGLSICRS-- 614
|
810
....*....|
gi 260177206 817 iIVKQHAGSI 826
Cdd:COG4192 615 -IMQQFGGDL 623
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
431-843 |
5.91e-42 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 160.53 E-value: 5.91e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 431 RLVEERTR-ELAHRQAE--LRVTFDNMGDGVVMFNEEMRLAAWNRNLQEILDLPDSFFTEPRTYRdyiayLIKHGEFGDV 507
Cdd:COG5809 124 RDITERKRmEEALRESEekFRLIFNHSPDGIIVTDLDGRIIYANPAACKLLGISIEELIGKSILE-----LIHSDDQENV 198
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 508 D-LDAELQRQVEHADRQRRIERTRPDGRVLEIRVNPVP----GGGFVAIYSDITERKKAEErvraardaaeaalrelkaa 582
Cdd:COG5809 199 AaFISQLLKDGGIAQGEVRFWTKDGRWRLLEASGAPIKkngeVDGIVIIFRDITERKKLEE------------------- 259
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 583 qnRLVQAEKLASLGQLTAGIAHEIKNPLNFVNNFsavsVELIdelreaLAGAHLDGKLQTEIgeiadMLQgnldkvvqHG 662
Cdd:COG5809 260 --LLRKSEKLSVVGELAAGIAHEIRNPLTSLKGF----IQLL------KDTIDEEQKTYLDI-----MLS--------EL 314
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 663 KRADSIVKNMLLHSRQGSGDHRPIDINALVEESLNL----AYHGaraekpgfNITLErcFDQAAGEVDLF--PQEITRVL 736
Cdd:COG5809 315 DRIESIISEFLVLAKPQAIKYEPKDLNTLIEEVIPLlqpqALLK--------NVQIE--LELEDDIPDILgdENQLKQVF 384
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 737 LNLISNGFyaatkrKADANGGSyepTLAATTKNLGDSVEIKIRDNGTGIPPEVKEKMFNPFFTTKPagEGTGLGLSLSHD 816
Cdd:COG5809 385 INLLKNAI------EAMPEGGN---ITIETKAEDDDKVVISVTDEGCGIPEERLKKLGEPFYTTKE--KGTGLGLMVSYK 453
|
410 420
....*....|....*....|....*..
gi 260177206 817 IIvKQHAGSIEVDTKPGEFTEFRIVLP 843
Cdd:COG5809 454 II-EEHGGKITVESEVGKGTTFSITLP 479
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
435-845 |
6.13e-38 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 148.73 E-value: 6.13e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 435 ERTRELAHRQ-AELRVTFDNMGDGVVMFNEEMRLAAWNRNLQEILDLPDSffteprtyrDYIAyliKHG-EFGDVDLDAE 512
Cdd:COG5805 146 KKIEEILQEQeERLQTLIENSPDLICVIDTDGRILFINESIERLFGAPRE---------ELIG---KNLlELLHPCDKEE 213
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 513 LQRQVEHADRQRR---IERTRP--DGRVLEIRVNPVP-----GG--GFVAIYSDITERKKAEERvraardaaeaalrelk 580
Cdd:COG5805 214 FKERIESITEVWQefiIEREIItkDGRIRYFEAVIVPlidtdGSvkGILVILRDITEKKEAEEL---------------- 277
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 581 aaqnrLVQAEKLASLGQLTAGIAHEIKNPLNFVNNFsavsVELIDELREAlagahldgklQTEIGEIadMLQgNLDkvvq 660
Cdd:COG5805 278 -----MARSEKLSIAGQLAAGIAHEIRNPLTSIKGF----LQLLQPGIED----------KEEYFDI--MLS-ELD---- 331
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 661 hgkRADSIVKNMLLHSRQGSGDHRPIDINALVEESLNLAYHGARAEkpgfNITLERCFDQAAGEVDLFPQEITRVLLNLI 740
Cdd:COG5805 332 ---RIESIISEFLALAKPQAVNKEKENINELIQDVVTLLETEAILH----NIQIRLELLDEDPFIYCDENQIKQVFINLI 404
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 741 SNGFyaatkrKADANGGsyepTLAATTKNLGDSVEIKIRDNGTGIPPEVKEKMFNPFFTTKPagEGTGLGLSLSHDIIvK 820
Cdd:COG5805 405 KNAI------EAMPNGG----TITIHTEEEDNSVIIRVIDEGIGIPEERLKKLGEPFFTTKE--KGTGLGLMVSYKII-E 471
|
410 420
....*....|....*....|....*
gi 260177206 821 QHAGSIEVDTKPGEFTEFRIVLPRS 845
Cdd:COG5805 472 NHNGTIDIDSKVGKGTTFTITLPLS 496
|
|
| PAS_7 |
pfam12860 |
PAS fold; The PAS fold corresponds to the structural domain that has previously been defined ... |
451-563 |
2.89e-36 |
|
PAS fold; The PAS fold corresponds to the structural domain that has previously been defined as PAS and PAC motifs. The PAS fold appears in archaea, eubacteria and eukarya.
Pssm-ID: 432837 [Multi-domain] Cd Length: 115 Bit Score: 132.66 E-value: 2.89e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 451 FDNMGDGVVMFNEEMRLAAWNRNLQEILDLPDSFFTEPRTYRDYIAYLIKHGEFGDVDLDAELQRQVEHADRQRR--IER 528
Cdd:pfam12860 1 LENMSQGLSVFDADLRLVAWNRRYRELLDLPEDLVQVGVPFEEIIRYNAERGEYGPGDVEAHVRRRLAAARAGSPhyFER 80
|
90 100 110
....*....|....*....|....*....|....*
gi 260177206 529 TRPDGRVLEIRVNPVPGGGFVAIYSDITERKKAEE 563
Cdd:pfam12860 81 ERPDGRVIEIRGNPLPDGGFVTTFTDITERRRAEE 115
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
484-845 |
3.41e-36 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 139.66 E-value: 3.41e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 484 FFTEPRTYRDYIAYLIKHGEFGDVDLDAELQRQVEHADRQRRIERTRPDGRVLEIRVNPVPGGGFVAIYSDITERKKAEE 563
Cdd:COG0642 1 LLLLLLLLVLLLLLLLLLLLALLLLLLLLLLLALLLLLALLLLLLLLLLLLLLLALALLALLLLLLLLLLLLLLLLLLLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 564 RVRAARDAAEAALRELKAAQNRLVQAEklASLGQLTAGIAHEIKNPLNFVNNFsavsVELIDElrealagahldgklqte 643
Cdd:COG0642 81 LLLLLLLLLLLLLLLLLALLLLLEEAN--EAKSRFLANVSHELRTPLTAIRGY----LELLLE----------------- 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 644 igEIADMLQGNLDKVVQHGKRADSIVKNMLLHSRQGSG----DHRPIDINALVEESLNLAYHGARAEkpgfNITLERCFD 719
Cdd:COG0642 138 --ELDEEQREYLETILRSADRLLRLINDLLDLSRLEAGklelEPEPVDLAELLEEVVELFRPLAEEK----GIELELDLP 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 720 QAAGEVDLFPQEITRVLLNLISNGFyaatkrKADANGGsyepTLAATTKNLGDSVEIKIRDNGTGIPPEVKEKMFNPFFT 799
Cdd:COG0642 212 DDLPTVRGDPDRLRQVLLNLLSNAI------KYTPEGG----TVTVSVRREGDRVRISVEDTGPGIPPEDLERIFEPFFR 281
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 260177206 800 TKPA--GEGTGLGLSLSHDiIVKQHAGSIEVDTKPGEFTEFRIVLPRS 845
Cdd:COG0642 282 TDPSrrGGGTGLGLAIVKR-IVELHGGTIEVESEPGKGTTFTVTLPLA 328
|
|
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
578-847 |
2.54e-33 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 128.49 E-value: 2.54e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 578 ELKAAQNRLVQAEKLASlgQLTAGIAHEIKNPLNFVNNFSAVsvelidelrealagahldgkLQTEIGEIADMLQGNLDK 657
Cdd:COG2205 1 ELEEALEELEELERLKS--EFLANVSHELRTPLTSILGAAEL--------------------LLDEEDLSPEERRELLEI 58
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 658 VVQHGKRADSIVKNMLLHSRQGSGDHR----PIDINALVEESLNLAYHgaRAEKPGFNITLERCFDQAAGEVDlfPQEIT 733
Cdd:COG2205 59 IRESAERLLRLIEDLLDLSRLESGKLSlelePVDLAELLEEAVEELRP--LAEEKGIRLELDLPPELPLVYAD--PELLE 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 734 RVLLNLISNGFyaatkrKADANGGsyepTLAATTKNLGDSVEIKIRDNGTGIPPEVKEKMFNPFFTTKPAG--EGTGLGL 811
Cdd:COG2205 135 QVLANLLDNAI------KYSPPGG----TITISARREGDGVRISVSDNGPGIPEEELERIFERFYRGDNSRgeGGTGLGL 204
|
250 260 270
....*....|....*....|....*....|....*.
gi 260177206 812 SLSHDiIVKQHAGSIEVDTKPGEFTEFRIVLPRSAA 847
Cdd:COG2205 205 AIVKR-IVEAHGGTIWVESEPGGGTTFTVTLPLAES 239
|
|
| KinD |
COG5808 |
Sporulation sensor histidine kinase D [Cell cycle control, cell division, chromosome ... |
580-847 |
3.74e-32 |
|
Sporulation sensor histidine kinase D [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444510 [Multi-domain] Cd Length: 454 Bit Score: 130.64 E-value: 3.74e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 580 KAAQNRLVQA---EKLASLGQLTAGIAHEIKNPLNFVNNFsavsVELidelrealagahldgkLQTEIGEIADmlQGNLD 656
Cdd:COG5808 223 KTLLERVIQEintQKLELIGTFAASTAHEIRNPLTSIKGF----IQL----------------LQEKYPELED--QKYFD 280
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 657 KVVQHGKRADSIVKNMLLHSRQGSGDHRPIDINALVEESLNLAYHGARaekpGFNITLERCFDQAAGEVDLFPQEITRVL 736
Cdd:COG5808 281 IIQEEIQRINQIVSEFLVLGKPTAKKLELDDLNELIEEILSIIDSEAN----LKNIRVEKQSLDEPLHIKCDKDRIKQVL 356
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 737 LNLISNGFyaatkrKADANGGsyepTLAATTKNLGDSVEIKIRDNGTGIPPEVKEKMFNPFFTTKpaGEGTGLGLSLSHD 816
Cdd:COG5808 357 LNLIKNAI------EAMKEGG----KLTISIENDDEKAVIEVIDNGEGIPEDIIDEIFEPFVTTK--EGGTGLGLSVCKR 424
|
250 260 270
....*....|....*....|....*....|.
gi 260177206 817 IIvKQHAGSIEVDTKPGEFTEFRIVLPRSAA 847
Cdd:COG5808 425 IV-EMHGGEIDIESEEGKGTTFTIRLPLKKE 454
|
|
| HATPase_AtoS-like |
cd16943 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
729-844 |
3.99e-32 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.
Pssm-ID: 340419 [Multi-domain] Cd Length: 105 Bit Score: 120.22 E-value: 3.99e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 729 PQEITRVLLNLISNGFYAATKRKadanggsyepTLAATTKNLGDSVEIKIRDNGTGIPPEVKEKMFNPFFTTKPAGEGTG 808
Cdd:cd16943 1 PSQLNQVLLNLLVNAAQAMEGRG----------RITIRTWAHVDQVLIEVEDTGSGIDPEILGRIFDPFFTTKPVGEGTG 70
|
90 100 110
....*....|....*....|....*....|....*.
gi 260177206 809 LGLSLSHDIIVKqHAGSIEVDTKPGEFTEFRIVLPR 844
Cdd:cd16943 71 LGLSLSYRIIQK-HGGTIRVASVPGGGTRFTIILPI 105
|
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
403-847 |
4.64e-30 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 123.12 E-value: 4.64e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 403 RAVEIFRRNAVDLDHLLAERAEAATRLERLVEERTRELAHRQAELRVTFDNMGDGVVMFNEEMRLAAWNRNLQEILDLPD 482
Cdd:COG5002 3 LLLLLLLALLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLALLLLLLLLLLLLLALLLLLLLLLLLLALA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 483 SFFTEPRTYRDYIAYLIKHGEFGDVDLDAELQRQVEHADRQRRIERTRPDGRVLEIRVNPVPGGGFVAIYSDITERKKAE 562
Cdd:COG5002 83 LLLLALLLLLLLLLLLLALLILLLLLALLILLAALLLLLSELLLLLLLLGRLSLRLSALLLGLLLLAAVERDITELERLE 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 563 ErvraardaaeaalrelkaAQNRLVqaeklaslgqltAGIAHEIKNPLNFVNNFsavsVELidelrealagahldgkLQT 642
Cdd:COG5002 163 Q------------------MRREFV------------ANVSHELRTPLTSIRGY----LEL----------------LLD 192
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 643 EIGEIADMLQGNLDKVVQHGKRADSIVKNMLLHSRQGSGDHR----PIDINALVEESLNLAyhGARAEKPGFNITLERCF 718
Cdd:COG5002 193 GAADDPEERREYLEIILEEAERLSRLVNDLLDLSRLESGELKlekePVDLAELLEEVVEEL--RPLAEEKGIELELDLPE 270
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 719 DQAAGEVDlfPQEITRVLLNLISNGFyaatkrKADANGGsyepTLAATTKNLGDSVEIKIRDNGTGIPPEVKEKMFNPFF 798
Cdd:COG5002 271 DPLLVLGD--PDRLEQVLTNLLDNAI------KYTPEGG----TITVSLREEDDQVRISVRDTGIGIPEEDLPRIFERFY 338
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|...
gi 260177206 799 TTKPA----GEGTGLGLSLSHDiIVKQHAGSIEVDTKPGEFTEFRIVLPRSAA 847
Cdd:COG5002 339 RVDKSrsreTGGTGLGLAIVKH-IVEAHGGRIWVESEPGKGTTFTITLPLARE 390
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
312-847 |
7.25e-30 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 124.90 E-value: 7.25e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 312 ATVVEQLVDRARRDIDTATAQAYSVQTFGGAVQLGVVALSLISSVLIVWLYVGRNIVARLMNLSGIMTAIAGGSRSVAVP 391
Cdd:COG4251 1 LLLLALLLLLLLLLLLLLLLLLLLLLVLLLALALLLLLALLVLLLLLIRLLLLLLLSLLALLLLLLLLLLLLLVLAALAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 392 VAGTDEIGAMGRAVEIFRRNAVDLDHLLAERAEAATRLERLVEERTRELAHRQAELRVTFDNMGDGVVMFNEEMRLAAWN 471
Cdd:COG4251 81 LLLLLLLELALVLLALLLVLLLLLALLLLLALLLLLELLLLLLALLLLLLLLALLLLEELALLRLALALLLLLLLLLLLL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 472 RNLQEILDLPDSFFTEPRTYRDYIAYLIKHGEFGDVDLDAELQRQVEHADRQRRIERTRPDGRVLEIRVNPVPGGGFVAI 551
Cdd:COG4251 161 LLLLALILALLLAALAELELLLLLLLVLLLLLLLLLLLLLLLLRLLLELLLLLEAELLLSLGGGLGLLLLLLLLLVLLLL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 552 YSDITERKKAEERVRAARDAAEAALRELKAAQNRLVQAEKlaSLGQLTAGIAHEIKNPLNFVNNFSavsvELIDElreal 631
Cdd:COG4251 241 LILLLLLLILVLELLELRLELEELEEELEERTAELERSNE--ELEQFAYVASHDLREPLRKISGFS----QLLEE----- 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 632 agaHLDGKLQTEIgeiadmlQGNLDKVVQHGKRADSIVKNMLLHSRQGSGD--HRPIDINALVEESLNLayHGARAEKPG 709
Cdd:COG4251 310 ---DYGDKLDEEG-------REYLERIRDAAERMQALIDDLLAYSRVGRQEleFEPVDLNELLEEVLED--LEPRIEERG 377
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 710 FNITLErcfdqAAGEVDLFPQEITRVLLNLISNGF-YAATKRKadanggsyePTLAATTKNLGDSVEIKIRDNGTGIPPE 788
Cdd:COG4251 378 AEIEVG-----PLPTVRGDPTLLRQVFQNLISNAIkYSRPGEP---------PRIEIGAEREGGEWVFSVRDNGIGIDPE 443
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 260177206 789 VKEKMFNPFFT--TKPAGEGTGLGLSLSHDiIVKQHAGSIEVDTKPGEFTEFRIVLPRSAA 847
Cdd:COG4251 444 YAEKIFEIFQRlhSRDEYEGTGIGLAIVKK-IVERHGGRIWVESEPGEGATFYFTLPKAPA 503
|
|
| PRK10364 |
PRK10364 |
two-component system sensor histidine kinase ZraS; |
578-843 |
1.23e-29 |
|
two-component system sensor histidine kinase ZraS;
Pssm-ID: 236674 [Multi-domain] Cd Length: 457 Bit Score: 123.36 E-value: 1.23e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 578 ELKAAQNRlvqAEKLASLGQLTAGIAHEIKNPLNFVNNFSAVSVElidelrEALAGahldgklqTEIGEIADMLQGNLDk 657
Cdd:PRK10364 223 LLQDEMKR---KEKLVALGHLAAGVAHEIRNPLSSIKGLAKYFAE------RAPAG--------GEAHQLAQVMAKEAD- 284
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 658 vvqhgkRADSIVKNMLLHSRQGSGDHRPIDINALVEESLNLAYHGARAEKpgfnITLERCFDQAAGEVDLFPQEITRVLL 737
Cdd:PRK10364 285 ------RLNRVVSELLELVKPTHLALQAVDLNDLINHSLQLVSQDANSRE----IQLRFTANDTLPEIQADPDRLTQVLL 354
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 738 NLISNGFYAATKrkadanGGsyepTLAATTKNLGDSVEIKIRDNGTGIPPEVKEKMFNPFFTTKpaGEGTGLGLSLSHDi 817
Cdd:PRK10364 355 NLYLNAIQAIGQ------HG----VISVTASESGAGVKISVTDSGKGIAADQLEAIFTPYFTTK--AEGTGLGLAVVHN- 421
|
250 260
....*....|....*....|....*.
gi 260177206 818 IVKQHAGSIEVDTKPGEFTEFRIVLP 843
Cdd:PRK10364 422 IVEQHGGTIQVASQEGKGATFTLWLP 447
|
|
| PRK13557 |
PRK13557 |
histidine kinase; Provisional |
554-856 |
1.77e-27 |
|
histidine kinase; Provisional
Pssm-ID: 237425 [Multi-domain] Cd Length: 540 Bit Score: 117.85 E-value: 1.77e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 554 DITERKKAEERvraardaaeaalrelkaaqnrLVQAEKLASLGQLTAGIAHEIknplnfvNNFSAVSVELIDELREALAG 633
Cdd:PRK13557 143 DVSRRRDAEDA---------------------LRQAQKMEALGQLTGGIAHDF-------NNLLQVMSGYLDVIQAALSH 194
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 634 AHLDgklqteigeiADMLQGNLDKVVQHGKRADSIVKNMLLHSRQGSGDHRPIDINALVEESLNLAYHGAraekpGFNIT 713
Cdd:PRK13557 195 PDAD----------RGRMARSVENIRAAAERAATLTQQLLAFARKQRLEGRVLNLNGLVSGMGELAERTL-----GDAVT 259
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 714 LERCFDQAAGEVDLFPQEITRVLLNLISNGfyaatkRKADANGGsyepTLAATTKNL---------------GDSVEIKI 778
Cdd:PRK13557 260 IETDLAPDLWNCRIDPTQAEVALLNVLINA------RDAMPEGG----RVTIRTRNVeiededlamyhglppGRYVSIAV 329
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 260177206 779 RDNGTGIPPEVKEKMFNPFFTTKPAGEGTGLGLSLSHDiIVKQHAGSIEVDTKPGEFTEFRIVLPRSAATIAKSGERT 856
Cdd:PRK13557 330 TDTGSGMPPEILARVMDPFFTTKEEGKGTGLGLSMVYG-FAKQSGGAVRIYSEVGEGTTVRLYFPASDQAENPEQEPK 406
|
|
| PRK13837 |
PRK13837 |
two-component system VirA-like sensor kinase; |
578-846 |
3.06e-27 |
|
two-component system VirA-like sensor kinase;
Pssm-ID: 237526 [Multi-domain] Cd Length: 828 Bit Score: 118.63 E-value: 3.06e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 578 ELKAAQNRLVQAEKLASLGQLTAGIAHEIKNPLNFVNNFSAVSVELIDelREALAGAHLDgklqtEIgeiadmlqgnldk 657
Cdd:PRK13837 433 ERDALERRLEHARRLEAVGTLASGIAHNFNNILGAILGYAEMALNKLA--RHSRAARYID-----EI------------- 492
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 658 vVQHGKRADSIVKNMLLHSRQGSGDHRPIDINALVEESLNLayhgARAEKPGfNITLERCFDQAAGEVDLFPQEITRVLL 737
Cdd:PRK13837 493 -ISAGARARLIIDQILAFGRKGERNTKPFDLSELVTEIAPL----LRVSLPP-GVELDFDQDQEPAVVEGNPAELQQVLM 566
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 738 NLISNGFYAATKR-----KADANGGSYEPTLAATTKNLGDSVEIKIRDNGTGIPPEVKEKMFNPFFTTKPAgeGTGLGLS 812
Cdd:PRK13837 567 NLCSNAAQAMDGAgrvdiSLSRAKLRAPKVLSHGVLPPGRYVLLRVSDTGAGIDEAVLPHIFEPFFTTRAG--GTGLGLA 644
|
250 260 270
....*....|....*....|....*....|....
gi 260177206 813 LSHDIIVkQHAGSIEVDTKPGEFTEFRIVLPRSA 846
Cdd:PRK13837 645 TVHGIVS-AHAGYIDVQSTVGRGTRFDVYLPPSS 677
|
|
| KinB |
COG5806 |
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome ... |
584-845 |
3.59e-27 |
|
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444508 [Multi-domain] Cd Length: 412 Bit Score: 114.96 E-value: 3.59e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 584 NRLVQAEKLASLGQLTAGIAHEIKNPLNFVNNFsavsVELIDELREalagahLDGKLQtEIGEIAdmlqgnLDKVvqhgK 663
Cdd:COG5806 190 KELQRAEKLEVVSELAASIAHEVRNPLTVVRGF----IQLLQEPEL------SDEKRK-QYIRIA------LEEL----D 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 664 RADSIVKNMLLHSRQGSGDHRPIDINALVEESLNL--AYhgarAEKPGFNITLErCFDQAAGEVDlfPQEITRVLLNLIS 741
Cdd:COG5806 249 RAEAIITDYLTFAKPQPEKLEKIDVSEELEHVIDVlsPY----ANMNNVEIQTE-LEPGLYIEGD--RQKLQQCLINIIK 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 742 NGFYAATkrkadaNGGsyepTLAATTKNLGDSVEIKIRDNGTGIPPEVKEKMFNPFFTTKpaGEGTGLGLSLSHDIIvKQ 821
Cdd:COG5806 322 NGIEAMP------NGG----TLTIDVSIDKNKVIISIKDTGVGMTKEQLERLGEPYFSTK--EKGTGLGTMVSYRII-EA 388
|
250 260
....*....|....*....|....
gi 260177206 822 HAGSIEVDTKPGEFTEFRIVLPRS 845
Cdd:COG5806 389 MNGTIRVESEVGKGTTFTITLPLA 412
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
428-847 |
1.14e-23 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 104.16 E-value: 1.14e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 428 RLERLVEERTRELAHRQAELRVTFDNMGDGVVMFNEEMRLAAWNRNLQEILDLPDsfftEPRTYRDYIAYLIKHGEFGdv 507
Cdd:COG3290 67 LLAALLLKLLEEIARLVEEREAVLESIREGVIAVDRDGRITLINDAARRLLGLDA----IGRPIDEVLAEVLETGERD-- 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 508 dldaelqrqvehadrqrriERTRPDGRVLEIRVNPVPGG----GFVAIYSDITERKKAEErvraardaaeaalrELKAAQ 583
Cdd:COG3290 141 -------------------EEILLNGRVLVVNRVPIRDDgrvvGAVATFRDRTELERLEE--------------ELEGVK 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 584 NrlvQAEKLASLgqltagiAHEIKNplnfvnnfsavsvelidelrealagahldgKLQTeigeIADMLQ-GNLDKVVQHg 662
Cdd:COG3290 188 E---LAEALRAQ-------RHDFRN------------------------------HLHT----ISGLLQlGEYDEALEY- 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 663 krADSIVKNMLLHSRQGSGDHRPIDINALVEESLNLAyhgaRAEKPGFNITLERCFDQAagEVDlfPQEITRVLLNLISN 742
Cdd:COG3290 223 --IDEISEELQELIDSLLSRIGNPVLAALLLGKAARA----RERGIDLTIDIDSDLPDL--PLS--DTDLVTILGNLLDN 292
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 743 GFYAATKRKADanggsyEPTLAATTKNLGDSVEIKIRDNGTGIPPEVKEKMFNPFFTTKPaGEGTGLGLSLSHDiIVKQH 822
Cdd:COG3290 293 AIEAVEKLPEE------ERRVELSIRDDGDELVIEVEDSGPGIPEELLEKIFERGFSTKL-GEGRGLGLALVKQ-IVEKY 364
|
410 420
....*....|....*....|....*
gi 260177206 823 AGSIEVDTKPGEFTEFRIVLPRSAA 847
Cdd:COG3290 365 GGTIEVESEEGEGTVFTVRLPKEGE 389
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
729-845 |
1.39e-22 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 93.48 E-value: 1.39e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 729 PQEITRVLLNLISNGFYAATKrkadanggsyEPTLAATTKNLGDSVEIKIRDNGTGIPPEVKEKMFNPFFTTKP---AGE 805
Cdd:smart00387 3 PDRLRQVLSNLLDNAIKYTPE----------GGRITVTLERDGDHVEITVEDNGPGIPPEDLEKIFEPFFRTDKrsrKIG 72
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 260177206 806 GTGLGLSLSHDiIVKQHAGSIEVDTKPGEFTEFRIVLPRS 845
Cdd:smart00387 73 GTGLGLSIVKK-LVELHGGEISVESEPGGGTTFTITLPLE 111
|
|
| glnL |
PRK11073 |
nitrogen regulation protein NR(II); |
583-843 |
2.95e-22 |
|
nitrogen regulation protein NR(II);
Pssm-ID: 182947 [Multi-domain] Cd Length: 348 Bit Score: 99.00 E-value: 2.95e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 583 QNRLVQaEKLASLGQLTA-----GIAHEIKNPLNfvnnfsavsvelidELREA---LAGAHLDGKLqTE----IGEIADM 650
Cdd:PRK11073 114 QRRLSQ-EQLQHAQQVAArdlvrGLAHEIKNPLG--------------GLRGAaqlLSKALPDPAL-TEytkvIIEQADR 177
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 651 LQGNLDKvvqhgkradsivknmlLHSRQGSGDHRPIDINALVEESLNLAyhgaRAEKPGfNITLERCFDQAAGEVDLFPQ 730
Cdd:PRK11073 178 LRNLVDR----------------LLGPQRPGTHVTESIHKVAERVVQLV----SLELPD-NVRLIRDYDPSLPELAHDPD 236
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 731 EITRVLLNLISNGFYAATKRkadanGG--------SYEPTLAATTKNLgdSVEIKIRDNGTGIPPEVKEKMFNPFFTTKP 802
Cdd:PRK11073 237 QIEQVLLNIVRNALQALGPE-----GGtitlrtrtAFQLTLHGERYRL--AARIDIEDNGPGIPPHLQDTLFYPMVSGRE 309
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 260177206 803 AgeGTGLGLSLSHDIIvKQHAGSIEVDTKPGEfTEFRIVLP 843
Cdd:PRK11073 310 G--GTGLGLSIARNLI-DQHSGKIEFTSWPGH-TEFSVYLP 346
|
|
| HATPase |
cd00075 |
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ... |
732-842 |
5.61e-22 |
|
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ATPase (HATPase) domains of several ATP-binding proteins such as histidine kinase, DNA gyrase B, topoisomerases, heat shock protein 90 (HSP90), phytochrome-like ATPases and DNA mismatch repair proteins. Domains belonging to this superfamily are also referred to as GHKL (gyrase, heat-shock protein 90, histidine kinase, MutL) ATPase domains.
Pssm-ID: 340391 [Multi-domain] Cd Length: 102 Bit Score: 91.13 E-value: 5.61e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 732 ITRVLLNLISNGFyaatkrKADANGGsyepTLAATTKNLGDSVEIKIRDNGTGIPPEVKEKMFNPFFTTKPA--GEGTGL 809
Cdd:cd00075 1 LEQVLSNLLDNAL------KYSPPGG----TIEISLRQEGDGVVLEVEDNGPGIPEEDLERIFERFYRGDKSreGGGTGL 70
|
90 100 110
....*....|....*....|....*....|...
gi 260177206 810 GLSLSHDiIVKQHAGSIEVDTKPGEFTEFRIVL 842
Cdd:cd00075 71 GLAIVRR-IVEAHGGRITVESEPGGGTTFTVTL 102
|
|
| HATPase_HupT_MifS-like |
cd16976 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
732-842 |
6.36e-22 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhodobacter capsulatus HupT and Pseudomonas aeruginosa MifS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Rhodobacter capsulatus HupT of the HupT-HupR two-component regulatory system (TCS), which regulates the synthesis of HupSL, a membrane bound [NiFe]hydrogenase. It also contains the HATPase domain of Pseudomonas aeruginosa MifS, the HK of the MifS-MifR TCS, which may be involved in sensing alpha-ketoglutarate and regulating its transport and subsequent metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also have a C-terminal PAS sensor domain.
Pssm-ID: 340435 [Multi-domain] Cd Length: 102 Bit Score: 90.98 E-value: 6.36e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 732 ITRVLLNLISNGfyaatkrkADANGGSYEPTLAATTKNLGDSVEIKIRDNGTGIPPEVKEKMFNPFFTTKPAGEGTGLGL 811
Cdd:cd16976 1 IQQVLMNLLQNA--------LDAMGKVENPRIRIAARRLGGRLVLVVRDNGPGIAEEHLSRVFDPFFTTKPVGKGTGLGL 72
|
90 100 110
....*....|....*....|....*....|.
gi 260177206 812 SLSHDiIVKQHAGSIEVDTKPGEFTEFRIVL 842
Cdd:cd16976 73 SISYG-IVEEHGGRLSVANEEGAGARFTFDL 102
|
|
| HATPase_CckA-like |
cd16919 |
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar ... |
735-843 |
7.52e-22 |
|
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar to Brucella abortus 2308 CckA; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) similar to Brucella abortus 2308 CckA, which is a component of an essential protein phosphorelay that regulates expression of genes required for growth, division, and intracellular survival; phosphoryl transfer initiates from the sensor kinase CckA and proceeds via the ChpT phosphotransferase to two regulatory substrates: the DNA-binding response regulator CtrA and the phospho-receiver protein CpdR. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), a REC signal receiver domain, and some contain PAS or PAS and GAF sensor domain(s).
Pssm-ID: 340396 [Multi-domain] Cd Length: 116 Bit Score: 91.29 E-value: 7.52e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 735 VLLNLISNGfyaatkRKADANGGSYEPTLAATTKNL-----------GDSVEIKIRDNGTGIPPEVKEKMFNPFFTTKPA 803
Cdd:cd16919 4 AILNLAVNA------RDAMPEGGRLTIETSNQRVDAdyalnyrdlipGNYVCLEVSDTGSGMPAEVLRRAFEPFFTTKEV 77
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 260177206 804 GEGTGLGLSLSHDiIVKQHAGSIEVDTKPGEFTEFRIVLP 843
Cdd:cd16919 78 GKGTGLGLSMVYG-FVKQSGGHLRIYSEPGVGTTVRIYLP 116
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
732-843 |
1.07e-19 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 85.11 E-value: 1.07e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 732 ITRVLLNLISNGFyaatkrKADANGGSYEPTLAAttknlGDSVEIKIRDNGTGIPPEVKEKMFNPFFTT-KPAGEGTGLG 810
Cdd:pfam02518 6 LRQVLSNLLDNAL------KHAAKAGEITVTLSE-----GGELTLTVEDNGIGIPPEDLPRIFEPFSTAdKRGGGGTGLG 74
|
90 100 110
....*....|....*....|....*....|...
gi 260177206 811 LSLSHDiIVKQHAGSIEVDTKPGEFTEFRIVLP 843
Cdd:pfam02518 75 LSIVRK-LVELLGGTITVESEPGGGTTVTLTLP 106
|
|
| HATPase_Glnl-NtrB-like |
cd16918 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
732-843 |
2.10e-19 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli GlnL (synonyms NtrB and NRII); This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs), similar to Escherichia coli GlnL/NtrB/NRII HK of the two-component regulatory system (TCS) GlnL/GlnG (NtrB-NtrC, or NRII-NRI), which regulates the transcription of genes encoding metabolic enzymes and permeases in response to carbon and nitrogen status in E. coli and related bacteria. Also included in this family are Rhodobacter capsulatus NtrB, Azospirillum brasilense NtrB, Vibrio alginolyticus NtrB, Rhizobium leguminosarum biovar phaseoli NtrB, and Herbaspirillum seropedicae NtrB. Escherichia coli GlnL/NtrB/NRII is both a kinase and a phosphatase, catalyzing the phosphorylation and dephosphorylation of GlnG/NtrC/NRI. The kinase and phosphatase activities of GlnL/NtrB/NRII are regulated by the PII signal transduction protein, which on binding to GlnL/NtrB/NRII, inhibits the kinase activity of GlnL/NtrB/NRII and activates the GlnL/NtrB/NRII phosphatase activity. Proteins having this HATPase domain also have a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also contain PAS sensor domain(s).
Pssm-ID: 340395 [Multi-domain] Cd Length: 109 Bit Score: 84.37 E-value: 2.10e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 732 ITRVLLNLISNGFYAAtkrkaDANGG--------SYEPTLAATTKNLGDSVEIKirDNGTGIPPEVKEKMFNPFFTTKPa 803
Cdd:cd16918 1 LIQVFLNLVRNAAQAL-----AGSGGeiilrtrtQRQVTLGHPRHRLALRVSVI--DNGPGIPPDLQDTIFYPMVSGRE- 72
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 260177206 804 gEGTGLGLSLSHDIIvKQHAGSIEVDTKPGEfTEFRIVLP 843
Cdd:cd16918 73 -NGTGLGLAIAQNIV-SQHGGVIECDSQPGH-TVFSVSLP 109
|
|
| HATPase_TmoS-FixL-DctS-like |
cd16920 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
732-843 |
6.10e-18 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhizobium meliloti FixL, and Rhodobacter capsulatus DctS; includes hybrid sensor histidine kinase similar to Pseudomonas mendocina TmoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs), such as Pseudomonas mendocina TmoS HK of the TmoS-TmoT TCS, which controls the expression of the toluene-4-monooxygenase pathway, Rhizobium meliloti FixL HK of the FixL-FixJ TCS, which regulates the expression of the genes related to nitrogen fixation in the root nodule in response to O(2) levels, and Rhodobacter capsulatus DctS of the DctS-DctR TCS, which controls synthesis of the high-affinity C4-dicarboxylate transport system. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and PAS sensor domain(s); many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340397 [Multi-domain] Cd Length: 104 Bit Score: 79.75 E-value: 6.10e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 732 ITRVLLNLISNGFYAAtkrkADANGGSYEPTLAaTTKNLGDSVEIKIRDNGTGIPPEVKEKMFNPFFTTKPAGEGTGLGL 811
Cdd:cd16920 1 IQQVLINLVRNGIEAM----SEGGCERRELTIR-TSPADDRAVTISVKDTGPGIAEEVAGQLFDPFYTTKSEGLGMGLSI 75
|
90 100 110
....*....|....*....|....*....|..
gi 260177206 812 SLShdiIVKQHAGSIEVDTKPGEFTEFRIVLP 843
Cdd:cd16920 76 CRS---IIEAHGGRLSVESPAGGGATFQFTLP 104
|
|
| HATPase_DpiB-CitA-like |
cd16915 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
738-843 |
1.87e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 DpiB, DcuS, and Bacillus subtilis CitS, DctS, and YufL; This family includes histidine kinase-like ATPase domains of Escherichia coli K-12 DpiB and DcuS, and Bacillus subtilis CitS, DctS and MalK histidine kinases (HKs) all of which are two component transduction systems (TCSs). E. coli K-12 DpiB (also known as CitA) is the histidine kinase (HK) of DpiA-DpiB, a two-component signal transduction system (TCS) required for the expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. E. coli K-12 DcuS (also known as YjdH) is the HK of DcuS-DcuR, a TCS that in the presence of the extracellular C4-dicarboxlates, activates the expression of the genes of anaerobic fumarate respiration and of aerobic C4-dicarboxylate uptake. CitS is the HK of Bacillus subtilis CitS-CitT, a TCS which regulates expression of CitM, the Mg-citrate transporter. Bacillus subtilis DctS forms a tripartite sensor unit (DctS/DctA/DctB) for sensing C4 dicarboxylates. Bacillus subtilis MalK (also known as YfuL) is the HK of MalK-MalR (YufL-YufM) a TCS which regulates the expression of the malate transporters MaeN (YufR) and YflS, and is essential for utilization of malate in minimal medium. Proteins having this DpiB-CitA-like HATPase domain generally have sensor domains such as Cache and PAS, and a histidine kinase A (HisKA)-like SpoOB-type, alpha-helical domain.
Pssm-ID: 340392 [Multi-domain] Cd Length: 104 Bit Score: 72.71 E-value: 1.87e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 738 NLISNGFYAAtkrkADANGGSYEPTLAATTKnlGDSVEIKIRDNGTGIPPEVKEKMFNPFFTTKPAGEgTGLGLSLSHDi 817
Cdd:cd16915 7 NLIDNALDAL----AATGAPNKQVEVFLRDE--GDDLVIEVRDTGPGIAPELRDKVFERGVSTKGQGE-RGIGLALVRQ- 78
|
90 100
....*....|....*....|....*.
gi 260177206 818 IVKQHAGSIEVDTKPGEFTEFRIVLP 843
Cdd:cd16915 79 SVERLGGSITVESEPGGGTTFSIRIP 104
|
|
| HATPase_FilI-like |
cd16921 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
735-843 |
1.10e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Methanosaeta harundinacea FilI and some hybrid sensor histidine kinases; This family includes FilI, the histidine kinase (HK) component of FilI-FilRs, a two-component signal transduction system (TCS) of the methanogenic archaeon, Methanosaeta harundinacea, which is involved in regulating methanogenesis. The cytoplasmic HK core consists of a C-terminal HK-like ATPase domain (represented here) and a histidine kinase dimerization and phosphoacceptor domain (HisKA) domain, which, in FilI, are coupled to CHASE, HAMP, PAS, and GAF sensor domains. FilI-FilRs catalyzes the phosphotransfer between FilI (HK) and FilRs (FilR1 and FilR2, response regulators) of the TCS. TCSs are predicted to be of bacterial origin, and acquired by archaea by horizontal gene transfer. This model also includes related HATPase domains such as that of Synechocystis sp. PCC6803 phytochrome-like protein Cph1. Proteins having this HATPase domain and HisKA domain also have accessory sensor domains such as CHASE, GAF, HAMP and PAS; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340398 [Multi-domain] Cd Length: 105 Bit Score: 67.74 E-value: 1.10e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 735 VLLNLISNGFYAATKRKADANGGSYEPTlaattknlGDSVEIKIRDNGTGIPPEVKEKMFNPF--FTTKPAGEGTGLGLS 812
Cdd:cd16921 4 VLTNLLGNAIKFRRPRRPPRIEVGAEDV--------GEEWTFYVRDNGIGIDPEYAEKVFGIFqrLHSREEYEGTGVGLA 75
|
90 100 110
....*....|....*....|....*....|.
gi 260177206 813 LSHDIIvKQHAGSIEVDTKPGEFTEFRIVLP 843
Cdd:cd16921 76 IVRKII-ERHGGRIWLESEPGEGTTFYFTLP 105
|
|
| HATPase_EvgS-ArcB-TorS-like |
cd16922 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid ... |
735-843 |
2.32e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid sensor histidine kinases, similar to Escherichia coli EvgS, ArcB, TorS, BarA, RcsC; This family contains the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinases (HKs), including the following Escherichia coli HKs: EvgS, a HK of the EvgS-EvgA two-component system (TCS) that confers acid resistance; ArcB, a HK of the ArcB-ArcA TCS that modulates the expression of numerous genes in response to respiratory growth conditions; TorS, a HK of the TorS-TorR TCS which is involved in the anaerobic utilization of trimethylamine-N-oxide; BarA, a HK of the BarA-UvrY TCS involved in the regulation of carbon metabolism; and RcsC, a HK of the RcsB-RcsC TCS which regulates the expression of the capsule operon and of the cell division gene ftsZ. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), with most having accessory sensor domain(s) such as GAF, PAS and CHASE; many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340399 [Multi-domain] Cd Length: 110 Bit Score: 64.05 E-value: 2.32e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 735 VLLNLISNG--FyaaTKRkadangGSYEPTLAA-TTKNLGDSVEIKIRDNGTGIPPEVKEKMFNPFF-----TTKPAGeG 806
Cdd:cd16922 4 ILLNLLGNAikF---TEE------GEVTLRVSLeEEEEDGVQLRFSVEDTGIGIPEEQQARLFEPFSqadssTTRKYG-G 73
|
90 100 110
....*....|....*....|....*....|....*..
gi 260177206 807 TGLGLSLSHDiIVKQHAGSIEVDTKPGEFTEFRIVLP 843
Cdd:cd16922 74 TGLGLAISKK-LVELMGGDISVESEPGQGSTFTFTLP 109
|
|
| nifL_nitrog |
TIGR02938 |
nitrogen fixation negative regulator NifL; NifL is a modulator of the nitrogen fixation ... |
546-840 |
4.74e-12 |
|
nitrogen fixation negative regulator NifL; NifL is a modulator of the nitrogen fixation positive regulator protein NifA, and is therefore a negative regulator. It binds NifA. NifA and NifL are encoded by adjacent genes. [Central intermediary metabolism, Nitrogen fixation, Regulatory functions, Protein interactions]
Pssm-ID: 131984 [Multi-domain] Cd Length: 494 Bit Score: 69.16 E-value: 4.74e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 546 GGFVAIYSDITERKKAEERVraardaaeaalrELKAAQNRLVQAEKLASLGQLTAGIAHEIKNPLNFVN---------NF 616
Cdd:TIGR02938 239 PYLLLTIADISNLREEQERA------------RLSALQALMAEEERLEAIRETLSAAIHRLQGPMNLISaaisvlqrrGD 306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 617 SAVSVELIDELREALAG--AHLDgklqteigeiadmlqgNLDKVVQHgkRADSIVKnmllhsrqgsgdhrPIDINALVEE 694
Cdd:TIGR02938 307 DAGNPASAAMLQQALSAgrEHME----------------ALRQVIPQ--SPQEIVV--------------PVNLNQILRD 354
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 695 SLNLAYHGARAEkpgfNITLERCFDQAAGEVDLFPQEITRVLLNLISNGFyaatkrKADANGGSYEPTLAATTKNLGDSV 774
Cdd:TIGR02938 355 VITLSTPRLLAA----GIVVDWQPAATLPAILGRELQLRSLFKALVDNAI------EAMNIKGWKRRELSITTALNGDLI 424
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 260177206 775 EIKIRDNGTGIPPEVKEKMFNPFFTTKPA-GEGTGLGLSLSHDiIVKQHAGSIEVDTKPGE----FTEFRI 840
Cdd:TIGR02938 425 VVSILDSGPGIPQDLRYKVFEPFFTTKGGsRKHIGMGLSVAQE-IVADHGGIIDLDDDYSEgcriIVEFRV 494
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
603-846 |
5.03e-12 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 69.10 E-value: 5.03e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 603 AHEIKNPLnfvnnfSAV--SVELideLREALAGahldgklqteigEIADMLQGNldkVVQHGKRADSIVKNML----LHS 676
Cdd:PRK11100 264 THELKSPL------AAIrgAAEL---LQEDPPP------------EDRARFTGN---ILTQSARLQQLIDRLLelarLEQ 319
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 677 RQGSGDHRPIDINALVEESLNlAYHGARAEKpgfNITLERCFDQAAGEVDLFpqEITRVLLNLISNGFYAAtkrkadANG 756
Cdd:PRK11100 320 RQELEVLEPVALAALLEELVE-AREAQAAAK---GITLRLRPDDARVLGDPF--LLRQALGNLLDNAIDFS------PEG 387
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 757 GsyEPTLAATTKnlGDSVEIKIRDNGTGIPPEVKEKMFNPFFTT-KPAGE--GTGLGLSLSHDIIvKQHAGSIEVDTKPG 833
Cdd:PRK11100 388 G--TITLSAEVD--GEQVALSVEDQGPGIPDYALPRIFERFYSLpRPANGrkSTGLGLAFVREVA-RLHGGEVTLRNRPE 462
|
250
....*....|...
gi 260177206 834 EFTEFRIVLPRSA 846
Cdd:PRK11100 463 GGVLATLTLPRHF 475
|
|
| HATPase_TutC-TodS-like |
cd16925 |
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas ... |
729-843 |
1.40e-11 |
|
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas putida TodS and Thauera aromatica TutC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) such Pseudomonas putida TodS HK of the TodS-TodT two-component regulatory system (TCS) which controls the expression of a toluene degradation pathway. Thauera aromatica TutC may be part of a TCS that is involved in anaerobic toluene metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), PAS sensor domain(s) and a REC domain.
Pssm-ID: 340402 [Multi-domain] Cd Length: 110 Bit Score: 62.12 E-value: 1.40e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 729 PQEITRVLLNLISNGFyaatkrKADANGGSYEPTLAATTKNlgdSVEIKIRDNGTGIPPEVKEKMFNPFFTTKPAGE--- 805
Cdd:cd16925 2 AEKYERVVLNLLSNAF------KFTPDGGRIRCILEKFRLN---RFLLTVSDSGPGIPPNLREEIFERFRQGDGSSTrah 72
|
90 100 110
....*....|....*....|....*....|....*....
gi 260177206 806 -GTGLGLSLSHDiIVKQHAGSIEVDTKPGEFTEFRIVLP 843
Cdd:cd16925 73 gGTGLGLSIVKE-FVELHGGTVTVSDAPGGGALFQVELP 110
|
|
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
592-843 |
2.88e-11 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 66.55 E-value: 2.88e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 592 LASLGQLTAGIAHEIKNPLNFVNnfsaVSVELIDELREALAGAhldgkLQTEIGEIadmlqgnldkvvqhgkraDSIVKN 671
Cdd:PRK10604 209 IASKKQLIDGIAHELRTPLVRLR----YRLEMSDNLSAAESQA-----LNRDIGQL------------------EALIEE 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 672 MLLHSR----QGSGDHRPIDINALVEESLnlayHGARAEKPGFNITLERCFDQAAGEVDlfPQEITRVLLNLISNGFYAA 747
Cdd:PRK10604 262 LLTYARldrpQNELHLSEPDLPAWLSTHL----ADIQAVTPEKTVRLDTPHQGDYGALD--MRLMERVLDNLLNNALRYA 335
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 748 TKRkadanggsyeptLAATTKNLGDSVEIKIRDNGTGIPPEVKEKMFNPFFTTKPAGE----GTGLGLSLSHDiIVKQHA 823
Cdd:PRK10604 336 HSR------------VRVSLLLDGNQACLIVEDDGPGIPPEERERVFEPFVRLDPSRDratgGCGLGLAIVHS-IALAMG 402
|
250 260
....*....|....*....|
gi 260177206 824 GSIEVDTKPGEFTEFRIVLP 843
Cdd:PRK10604 403 GSVNCDESELGGARFSFSWP 422
|
|
| HATPase_BvrS-ChvG-like |
cd16953 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
734-843 |
4.04e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Brucella abortus BvrS and Sinorhizobium meliloti ChvG; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Brucella abortus BvrS of the BvrR-BvrS two-component regulatory system (TCS), which controls cell invasion and intracellular survival, as well as Sinorhizobium meliloti and Agrobacterium tumefaciens ChvG of the ChvI-ChvG TCS necessary for endosymbiosis and pathogenicity in plants. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), an accessory HAMP sensor domain, a periplasmic stimulus-sensing domain, and some also have a sensor N-terminal transmembrane domain.
Pssm-ID: 340429 [Multi-domain] Cd Length: 110 Bit Score: 60.66 E-value: 4.04e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 734 RVLLNLISNgfyaATKRKADANGgsyepTLAATTKNLGDSVEIKIRDNGTGIPPEVKEKMFNPFFTTKPAGEG----TGL 809
Cdd:cd16953 3 QVLRNLIGN----AISFSPPDTG-----RITVSAMPTGKMVTISVEDEGPGIPQEKLESIFDRFYTERPANEAfgqhSGL 73
|
90 100 110
....*....|....*....|....*....|....*...
gi 260177206 810 GLSLSHDIIvKQHAGSI--EVDTKPGEFT--EFRIVLP 843
Cdd:cd16953 74 GLSISRQII-EAHGGISvaENHNQPGQVIgaRFTVQLP 110
|
|
| HATPase_CpxA-like |
cd16949 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
732-843 |
6.47e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CpxA; This family includes the histidine kinase-like ATPase (HATPase) domains of two-component sensor histidine kinase (HKs) similar to Escherichia coli CpxA, HK of the CpxA-CpxR two-component regulatory system (TCS) which may function in acid stress and in cell wall stability. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a CpxA family periplasmic domain.
Pssm-ID: 340425 [Multi-domain] Cd Length: 104 Bit Score: 60.03 E-value: 6.47e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 732 ITRVLLNLISNGF-YAATKRKADAnggSYEptlaattknlGDSVEIKIRDNGTGIPPEVKEKMFNPFFTTKPA----GEG 806
Cdd:cd16949 1 LARALENVLRNALrYSPSKILLDI---SQD----------GDQWTITITDDGPGVPEDQLEQIFLPFYRVDSArdreSGG 67
|
90 100 110
....*....|....*....|....*....|....*..
gi 260177206 807 TGLGLSLSHDIIvKQHAGSIEVDTKPGEFTEFRIVLP 843
Cdd:cd16949 68 TGLGLAIAERAI-EQHGGKIKASNRKPGGLRVRIWLP 103
|
|
| HATPase_NtrY-like |
cd16944 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
732-843 |
7.99e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Azorhizobium caulinodans NtrY; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Azorhizobium caulinodans ORS571 NtrY of the NtrY-NtrX TCS, which is involved in nitrogen fixation and metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also have PAS sensor domains.
Pssm-ID: 340420 [Multi-domain] Cd Length: 108 Bit Score: 59.86 E-value: 7.99e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 732 ITRVLLNLISNGFYAATKRKADANggsyEPTLAATTKNLGDSVeIKIRDNGTGIPPEVKEKMFNPFFTTKPAgeGTGLGL 811
Cdd:cd16944 5 ISQVLTNILKNAAEAIEGRPSDVG----EVRIRVEADQDGRIV-LIVCDNGKGFPREMRHRATEPYVTTRPK--GTGLGL 77
|
90 100 110
....*....|....*....|....*....|..
gi 260177206 812 SLSHDIIvKQHAGSIEVDTKPGEFTEFRIVLP 843
Cdd:cd16944 78 AIVKKIM-EEHGGRISLSNREAGGACIRIILP 108
|
|
| envZ |
PRK09467 |
osmolarity sensor protein; Provisional |
598-832 |
6.65e-10 |
|
osmolarity sensor protein; Provisional
Pssm-ID: 236531 [Multi-domain] Cd Length: 435 Bit Score: 62.24 E-value: 6.65e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 598 LTAGIAHEIKNPLNFVNNFSAVSVELIDELREALagahldgklqteIGEIADMlqgnldkvvqhgkraDSIVKNMLLHSR 677
Cdd:PRK09467 232 LMAGVSHDLRTPLTRIRLATEMMSEEDGYLAESI------------NKDIEEC---------------NAIIEQFIDYLR 284
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 678 QGSGDHR-PIDINALVEESLNlayhgarAEkPGFNITLERCFDQAAGEVDLFPQEITRVLLNLISNGF-YAatkrkadaN 755
Cdd:PRK09467 285 TGQEMPMeMADLNALLGEVIA-------AE-SGYEREIETALQPGPIEVPMNPIAIKRALANLVVNAArYG--------N 348
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 756 GgsyepTLAATTKNLGDSVEIKIRDNGTGIPPEVKEKMFNPFFTTKPA--GEGTGLGLSlshdI---IVKQHAGSIEVDT 830
Cdd:PRK09467 349 G-----WIKVSSGTEGKRAWFQVEDDGPGIPPEQLKHLFQPFTRGDSArgSSGTGLGLA----IvkrIVDQHNGKVELGN 419
|
..
gi 260177206 831 KP 832
Cdd:PRK09467 420 SE 421
|
|
| HATPase_BceS-YxdK-YvcQ-like |
cd16948 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
768-843 |
9.87e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.
Pssm-ID: 340424 [Multi-domain] Cd Length: 109 Bit Score: 56.53 E-value: 9.87e-10
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 260177206 768 KNLGDSVEIKIRDNGTGIPPEVKEKMFNPFFTTK---PAGEGTGLGLSLSHDIIVKQHAGsIEVDTKPGEFTEFRIVLP 843
Cdd:cd16948 32 ETNEQGVVLSIKDFGIGIPEEDLPRVFDKGFTGEngrNFQESTGMGLYLVKKLCDKLGHK-IDVESEVGEGTTFTITFP 109
|
|
| PRK11086 |
PRK11086 |
sensory histidine kinase DcuS; Provisional |
732-843 |
1.80e-09 |
|
sensory histidine kinase DcuS; Provisional
Pssm-ID: 236839 [Multi-domain] Cd Length: 542 Bit Score: 61.08 E-value: 1.80e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 732 ITrVLLNLISNGFyaatkrkaDANGGSYEPTLAATTKNLGDSVEIKIRDNGTGIPPEVKEKMFNPFFTTKpaGEGTGLGL 811
Cdd:PRK11086 435 IT-ILGNLIENAL--------EAVGGEEGGEISVSLHYRNGWLHCEVSDDGPGIAPDEIDAIFDKGYSTK--GSNRGVGL 503
|
90 100 110
....*....|....*....|....*....|....*.
gi 260177206 812 SLshdiiVKQH----AGSIEVDTKPGEFTEFRIVLP 843
Cdd:PRK11086 504 YL-----VKQSvenlGGSIAVESEPGVGTQFFVQIP 534
|
|
| HATPase_RstB-like |
cd16939 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
734-844 |
2.04e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Salmonella typhimurium RstB; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Salmonella typhimurium RstB HK of the RstA-RstB two-component regulatory system (TCS), which regulates expression of the constituents participating in pyrimidine metabolism and iron acquisition, and may be required for regulation of Salmonella motility and invasion. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensor domain.
Pssm-ID: 340416 [Multi-domain] Cd Length: 104 Bit Score: 55.51 E-value: 2.04e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 734 RVLLNLISNGFYAATKRKadanggsyepTLAATTKnlGDSVEIKIRDNGTGIPPEVKEKMFNPFFTTKPAGE----GTGL 809
Cdd:cd16939 3 RALDNLLRNALRYAHRTV----------RIALLVS--GGRLTLIVEDDGPGIPAAARERVFEPFVRLDPSRDratgGFGL 70
|
90 100 110
....*....|....*....|....*....|....*
gi 260177206 810 GLSLSHDIIVKqHAGSIEVDTKPGEFTEFRIVLPR 844
Cdd:cd16939 71 GLAIVHRVALW-HGGHVECDDSELGGACFRLTWPR 104
|
|
| HATPase_EnvZ-like |
cd16950 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
732-843 |
4.57e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli EnvZ and Pseudomonas aeruginosa BfmS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli EnvZ of the EnvZ-OmpR two-component regulatory system (TCS), which functions in osmoregulation. It also contains the HATPase domain of Pseudomonas aeruginosa BfmS, the HK of the BfmSR TCS, which functions in the regulation of the rhl quorum-sensing system and bacterial virulence in P. aeruginosa. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a periplasmic domain.
Pssm-ID: 340426 [Multi-domain] Cd Length: 101 Bit Score: 54.38 E-value: 4.57e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 732 ITRVLLNLISNGFYAAtkrkadanGGSYEptlaATTKNLGDSVEIKIRDNGTGIPPEVKEKMFNPFFTTKPA--GEGTGL 809
Cdd:cd16950 1 LKRVLSNLVDNALRYG--------GGWVE----VSSDGEGNRTRIQVLDNGPGIAPEEVDELFQPFYRGDNArgTSGTGL 68
|
90 100 110
....*....|....*....|....*....|....
gi 260177206 810 GLSLSHDIIvKQHAGSIEVDTKPGEFTEFRIVLP 843
Cdd:cd16950 69 GLAIVQRIS-DAHGGSLTLANRAGGGLCARIELP 101
|
|
| PRK11091 |
PRK11091 |
aerobic respiration control sensor protein ArcB; Provisional |
420-843 |
1.35e-08 |
|
aerobic respiration control sensor protein ArcB; Provisional
Pssm-ID: 236842 [Multi-domain] Cd Length: 779 Bit Score: 58.80 E-value: 1.35e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 420 AERAEAATRLERLVEERTR---ELAHRQAELRVTFDNMGDGVVMFNEEMRLAAWNRNLQEILDLpdsffTEprtyrdyiA 496
Cdd:PRK11091 127 EARQEAFEQLKNEIKEREEtqiELEQQSSLLRSFLDASPDLVYYRNEDGEFSGCNRAMELLTGK-----SE--------K 193
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 497 YLIKHGEFgDVdLDAELQRQVEHADRQrrIERTR-----------PDGR--VLEIRvnPVP-----GG--GFVAIYSDIT 556
Cdd:PRK11091 194 QLIGLTPK-DV-YSPEAAEKVIETDEK--VFRHNvsltyeqwldyPDGRkaCFELR--KVPfydrvGKrhGLMGFGRDIT 267
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 557 ERKKAEERVRaardaaeaalrelKAAQNRlvqaeklaslGQLTAGIAHEIKNPLNFVNNFSAV--SVELIDELREALAGA 634
Cdd:PRK11091 268 ERKRYQDALE-------------KASRDK----------TTFISTISHELRTPLNGIVGLSRIllDTELTAEQRKYLKTI 324
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 635 HLDG-KLQTEIGEIADMlqgnlDKvvqhgkradsivknmlLHSRQGSGDHRPIDINALVEESLNLAyhGARAEKPGFNIT 713
Cdd:PRK11091 325 HVSAiTLGNIFNDIIDM-----DK----------------MERRKLQLDNQPIDFTDFLADLENLS--GLQAEQKGLRFD 381
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 714 LERCFDqaagevdlFPQEI----TR---VLLNLISNgfyaATKRKADanGG-----SYEPtlaattknlGDSVEIKIRDN 781
Cdd:PRK11091 382 LEPLLP--------LPHKVitdgTRlrqILWNLISN----AVKFTQQ--GGvtvrvRYEE---------GDMLTFEVEDS 438
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 260177206 782 GTGIPPEVKEKMFNPFFT------TKPAgEGTGLGLSLSHDiIVKQHAGSIEVDTKPGEFTEFRIVLP 843
Cdd:PRK11091 439 GIGIPEDELDKIFAMYYQvkdshgGKPA-TGTGIGLAVSKR-LAQAMGGDITVTSEEGKGSCFTLTIH 504
|
|
| PRK09835 |
PRK09835 |
Cu(+)/Ag(+) sensor histidine kinase; |
599-846 |
2.96e-08 |
|
Cu(+)/Ag(+) sensor histidine kinase;
Pssm-ID: 182101 [Multi-domain] Cd Length: 482 Bit Score: 57.09 E-value: 2.96e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 599 TAGIAHEIKNPL-NFVNnfsavsvelidelrealagahldgklQTEIG--------EIADMLQGNLDKVvqhgKRADSIV 669
Cdd:PRK09835 266 SADIAHEIRTPItNLIT--------------------------QTEIAlsqsrsqkELEDVLYSNLEEL----TRMAKMV 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 670 KNMLL----HSRQGSGDHRPIDINALVEESLNlaYHGARAEKPgfNITLErcFDQAAGEVDLFPQEITRVLLNLISNGFy 745
Cdd:PRK09835 316 SDMLFlaqaDNNQLIPEKKMLDLADEVGKVFD--FFEAWAEER--GVELR--FVGDPCQVAGDPLMLRRAISNLLSNAL- 388
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 746 aatkrkadanggSYEPTLAATTKNL---GDSVEIKIRDNGTGIPPEVKEKMFNPFFTTKPA----GEGTGLGLSLSHDII 818
Cdd:PRK09835 389 ------------RYTPAGEAITVRCqevDHQVQLVVENPGTPIAPEHLPRLFDRFYRVDPSrqrkGEGSGIGLAIVKSIV 456
|
250 260
....*....|....*....|....*...
gi 260177206 819 VKqHAGSIEVDTKPgEFTEFRIVLPRSA 846
Cdd:PRK09835 457 VA-HKGTVAVTSDA-RGTRFVISLPRLE 482
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
579-843 |
3.39e-08 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 57.44 E-value: 3.39e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 579 LKAAQNRLVQAEKLASlgQLTAGIAHEIKNPLNFVNNF------SAVSVElidELREALAGAHLDGklQTEIGEIADMLq 652
Cdd:PRK09959 698 LEVERNKAINATVAKS--QFLATMSHEIRTPISSIMGFlellsgSGLSKE---QRVEAISLAYATG--QSLLGLIGEIL- 769
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 653 gNLDKVvqhgkradsivknmllhsRQGSGDHRP--IDINALVEESLNlaYHGARAEKPGFNITLERCF-DQAAGEVDlfP 729
Cdd:PRK09959 770 -DVDKI------------------ESGNYQLQPqwVDIPTLVQNTCH--SFGAIAASKSIALSCSSTFpDHYLVKID--P 826
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 730 QEITRVLLNLISNGFYAATKrkadangGSYEPTLAATTKNLGDSV-EIKIRDNGTGIPPEVKEKMFNPFFTTKPAGE--G 806
Cdd:PRK09959 827 QAFKQVLSNLLSNALKFTTE-------GAVKITTSLGHIDDNHAViKMTIMDSGSGLSQEEQQQLFKRYSQTSAGRQqtG 899
|
250 260 270
....*....|....*....|....*....|....*..
gi 260177206 807 TGLGLSLSHDIIvKQHAGSIEVDTKPGEFTEFRIVLP 843
Cdd:PRK09959 900 SGLGLMICKELI-KNMQGDLSLESHPGIGTTFTITIP 935
|
|
| PAS |
COG2202 |
PAS domain [Signal transduction mechanisms]; |
438-563 |
3.40e-08 |
|
PAS domain [Signal transduction mechanisms];
Pssm-ID: 441804 [Multi-domain] Cd Length: 258 Bit Score: 55.42 E-value: 3.40e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 438 RELAHRQAELRVTFDNMGDGVVMFNEEMRLAAWNRNLQEILDLPDSFFTEpRTYRDYIAylIKHGEFGDVDLDAELQRQV 517
Cdd:COG2202 130 EALRESEERLRLLVENAPDGIFVLDLDGRILYVNPAAEELLGYSPEELLG-KSLLDLLH--PEDRERLLELLRRLLEGGR 206
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 260177206 518 EHADRQRRIERTRPDGRVLEIRVNPVPGG----GFVAIYSDITERKKAEE 563
Cdd:COG2202 207 ESYELELRLKDGDGRWVWVEASAVPLRDGgeviGVLGIVRDITERKRAEE 256
|
|
| PRK09303 |
PRK09303 |
histidine kinase; |
729-843 |
3.83e-08 |
|
histidine kinase;
Pssm-ID: 236462 [Multi-domain] Cd Length: 380 Bit Score: 56.50 E-value: 3.83e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 729 PQEITRVLLNLISNGFyaatkrKADANGGSYEPT-LAATTKnlgdSVEIKIRDNGTGIPPEVKEKMFNPFFTTKPAG--E 805
Cdd:PRK09303 270 QERIRQVLLNLLDNAI------KYTPEGGTITLSmLHRTTQ----KVQVSICDTGPGIPEEEQERIFEDRVRLPRDEgtE 339
|
90 100 110
....*....|....*....|....*....|....*...
gi 260177206 806 GTGLGLSLSHDIIvKQHAGSIEVDTKPGEFTEFRIVLP 843
Cdd:PRK09303 340 GYGIGLSVCRRIV-RVHYGQIWVDSEPGQGSCFHFTLP 376
|
|
| HATPase_BasS-like |
cd16940 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
772-837 |
6.48e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BasS HK of the BasS-BasR two-component regulatory system (TCS). Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some contain a HAMP sensory domain, while some an N-terminal two-component sensor kinase domain.
Pssm-ID: 340417 [Multi-domain] Cd Length: 113 Bit Score: 51.64 E-value: 6.48e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 260177206 772 DSVEIKIRDNGTGIPPEVKEKMFNPFFTTKP-AGEGTGLGLSLSHDiIVKQHAGSIEVDTKPGEFTE 837
Cdd:cd16940 43 DGAVIRVEDNGPGIDEEELEALFERFYRSDGqNYGGSGLGLSIVKR-IVELHGGQIFLGNAQGGGLE 108
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
771-844 |
9.79e-08 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 55.41 E-value: 9.79e-08
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 260177206 771 GDSVEIKIRDNGTGIPPEVKEKMFNPFfttKPAGEGTGLGLSLSHDIIVKQH--AGSIEVDTKPGEFTEFRIVLPR 844
Cdd:COG2972 370 GDRLVITVEDNGVGMPEEKLEKLLEEL---SSKGEGRGIGLRNVRERLKLYYgeEYGLEIESEPGEGTTVTIRIPL 442
|
|
| Tar |
COG0840 |
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms]; |
177-435 |
2.38e-07 |
|
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
Pssm-ID: 440602 [Multi-domain] Cd Length: 533 Bit Score: 54.26 E-value: 2.38e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 177 LQGNVLQLRNKIDAASNSQERQAAINRFELAADTLEQIEREASVVFEFLTRAANTEDTGLLQSQASDARNSVRALKGRID 256
Cdd:COG0840 16 LLALSLLALLAAALLILLALLLAALTALALLLLLSLLALLLLLLLLALALLLVLLALLLLLALVVLLALLLALLLLLLAL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 257 DLERKLAEGLIDPTQRLNSIVTDVDGLFVTRTKEIEANRAGQRLLIANIALGDQLATVVEQLVDRARRDIDTATAQAYSV 336
Cdd:COG0840 96 LALALAALALLAALAALLALLELLLAALLAALAIALLALAALLALAALALALLALALLAAAAAAAAALAALLEAAALALA 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 337 QTFGGAVQLGVVALSLISSVLIVWLYVGRNIVARLMNLSGIMTAIAGGSRSVAVPVAGTDEIGAMGRAVEIFRRNavdLD 416
Cdd:COG0840 176 AAALALALLAAALLALVALAIILALLLSRSITRPLRELLEVLERIAEGDLTVRIDVDSKDEIGQLADAFNRMIEN---LR 252
|
250
....*....|....*....
gi 260177206 417 HLLAERAEAATRLERLVEE 435
Cdd:COG0840 253 ELVGQVRESAEQVASASEE 271
|
|
| PRK10841 |
PRK10841 |
two-component system sensor histidine kinase RcsC; |
771-843 |
3.44e-07 |
|
two-component system sensor histidine kinase RcsC;
Pssm-ID: 182772 [Multi-domain] Cd Length: 924 Bit Score: 54.21 E-value: 3.44e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 260177206 771 GDSVEIKIRDNGTGIPPEVKEKMFNPFFTTKPAGE----GTGLGLSLSHDIIvKQHAGSIEVDTKPGEFTEFRIVLP 843
Cdd:PRK10841 591 GDYLSFRVRDTGVGIPAKEVVRLFDPFFQVGTGVQrnfqGTGLGLAICEKLI-NMMDGDISVDSEPGMGSQFTIRIP 666
|
|
| HATPase_YcbM-like |
cd16947 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
734-842 |
6.19e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis YcbM; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis YcbM, a HK of the two-component system YcbM-YcbL. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA).
Pssm-ID: 340423 [Multi-domain] Cd Length: 125 Bit Score: 49.05 E-value: 6.19e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 734 RVLLNLISNGFyaatkrKADANGGSYEPTLAATTKNlgdsVEIKIRDNGTGIPPEVKEKMFNPFFTTK----PAGEGTGL 809
Cdd:cd16947 23 RILKNLISNAI------KYGSDGKFLGMTLREDEKH----VYIDIWDKGKGISETEKDHVFERLYTLEdsrnSAKQGNGL 92
|
90 100 110
....*....|....*....|....*....|...
gi 260177206 810 GLSLSHDiIVKQHAGSIEVDTKPGEFTEFRIVL 842
Cdd:cd16947 93 GLTITKR-LAESMGGSIYVNSKPYEKTVFTVTL 124
|
|
| PAS |
COG2202 |
PAS domain [Signal transduction mechanisms]; |
435-694 |
1.04e-06 |
|
PAS domain [Signal transduction mechanisms];
Pssm-ID: 441804 [Multi-domain] Cd Length: 258 Bit Score: 51.18 E-value: 1.04e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 435 ERTRELAHRQAELRVTFDNMGDGVVMFNEEMRLAAWNRNLQEILDLPDSFFTEpRTYRDyiaylIKHGEFGDVDLDAELQ 514
Cdd:COG2202 1 TAEEALEESERRLRALVESSPDAIIITDLDGRILYVNPAFERLTGYSAEELLG-KTLRD-----LLPPEDDDEFLELLRA 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 515 RQVEHADRQRRIERTRPDGRV--LEIRVNPVPGG-----GFVAIYSDITERKKAEErvraardaaeaalrelkaaqnRLV 587
Cdd:COG2202 75 ALAGGGVWRGELRNRRKDGSLfwVELSISPVRDEdgeitGFVGIARDITERKRAEE---------------------ALR 133
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 588 QAEKLASLGQLTAGIAHEIKNPLNFVNNFSAVSVELIDELREALAGAHLDgklQTEIGEIADMLQGNLDKVVQHGKRADS 667
Cdd:COG2202 134 ESEERLRLLVENAPDGIFVLDLDGRILYVNPAAEELLGYSPEELLGKSLL---DLLHPEDRERLLELLRRLLEGGRESYE 210
|
250 260
....*....|....*....|....*..
gi 260177206 668 IVknmlLHSRQGSGDHRPIDINALVEE 694
Cdd:COG2202 211 LE----LRLKDGDGRWVWVEASAVPLR 233
|
|
| PRK10490 |
PRK10490 |
sensor protein KdpD; Provisional |
732-843 |
1.46e-06 |
|
sensor protein KdpD; Provisional
Pssm-ID: 236701 [Multi-domain] Cd Length: 895 Bit Score: 51.96 E-value: 1.46e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 732 ITRVLLNLISNGF-YAAtkrkADANGGsyeptLAATTKnlGDSVEIKIRDNGTGIPPEVKEKMFNPFF--TTKPAGEGTG 808
Cdd:PRK10490 779 FERVLINLLENAVkYAG----AQAEIG-----IDAHVE--GERLQLDVWDNGPGIPPGQEQLIFDKFArgNKESAIPGVG 847
|
90 100 110
....*....|....*....|....*....|....*
gi 260177206 809 LGLSLSHdIIVKQHAGSIEVDTKPGEFTEFRIVLP 843
Cdd:PRK10490 848 LGLAICR-AIVEVHGGTIWAENRPEGGACFRVTLP 881
|
|
| sensory_box |
TIGR00229 |
PAS domain S-box; The PAS domain was previously described. This sensory box, or S-box domain ... |
443-563 |
1.87e-06 |
|
PAS domain S-box; The PAS domain was previously described. This sensory box, or S-box domain occupies the central portion of the PAS domain but is more widely distributed. It is often tandemly repeated. Known prosthetic groups bound in the S-box domain include heme in the oxygen sensor FixL, FAD in the redox potential sensor NifL, and a 4-hydroxycinnamyl chromophore in photoactive yellow protein. Proteins containing the domain often contain other regulatory domains such as response regulator or sensor histidine kinase domains. Other S-box proteins include phytochromes and the aryl hydrocarbon receptor nuclear translocator. [Regulatory functions, Small molecule interactions]
Pssm-ID: 272971 [Multi-domain] Cd Length: 124 Bit Score: 47.67 E-value: 1.87e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 443 RQAELRVTFDNMGDGVVMFNEEMRLAAWNRNLQEILDLpdsffTEPRTYRDYIAYLIKHGEFGDVDLDAELQRQVEHADR 522
Cdd:TIGR00229 1 SEERYRAIFESSPDAIIVIDLEGNILYVNPAFEEIFGY-----SAEELIGRNVLELIPEEDREEVRERIERRLEGEPEPV 75
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 260177206 523 QRRIERTRPDGRVLEIRVNPVP----GG--GFVAIYSDITERKKAEE 563
Cdd:TIGR00229 76 SEERRVRRKDGSEIWVEVSVSPirtnGGelGVVGIVRDITERKEAEE 122
|
|
| TorS_sensor_domain |
cd16172 |
sensor domain of the sensor histidine kinase TorS; TorS is part of the trimethylamine-N-oxide ... |
69-320 |
3.42e-06 |
|
sensor domain of the sensor histidine kinase TorS; TorS is part of the trimethylamine-N-oxide (TMAO) reductase (Tor) pathway, which consists TorT, a periplasmic binding protein that binds TMAO; TorS, a sensor histidine kinase that forms a complex with TorT, and TorR, the response regulator. The Tor pathway is involved in regulating a cellular response to trimethylamine-N-oxide (TMAO), a terminal electron receptor in anaerobic respiration. TorS consists of a periplasmic sensor domain, as well as a HAMP domain, a histidine kinase domain, and a receiver domain.
Pssm-ID: 293930 [Multi-domain] Cd Length: 261 Bit Score: 49.50 E-value: 3.42e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 69 RESEQVLAVGPRMLSARTDDEVKRRSMAASDGLVNIGRLVDELRATIVDPLDTERLTSYVTNLRSNLSQFEVVASERVRA 148
Cdd:cd16172 6 ELSSRIIASAQLLANADSEAERQQQGRQLTAQLEALLRLLKALGQDSFDSFLLSRLEQTVQEIIDNLAQLGELVGQRLQL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 149 AIRREKLVNDTFAAYHE-FRTAWGQ-HYAEL-----QGNVLQLRNKidaaSNSQERQAAINRfeLAADTLEQIER----- 216
Cdd:cd16172 86 RQQFQQLFERLRAAAGElAQLARTQvANASTiavanVSGLYDLIEQ----NDKEAAYQALDR--LIEVDLDLLERmhelr 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 217 -EASVVFEFLTRAANTEDTGLLQSQASDARNSVRALKGRIDDLErklaegliDPT--QRLNSIVTDV---DGLFVTRTKE 290
Cdd:cd16172 160 lLALQLGNLINELRTASDIARLAELRQQFNANLAILQRRVQAVE--------DPGrrAQMAQLLSDLeqgQGLFALRRQL 231
|
250 260 270
....*....|....*....|....*....|
gi 260177206 291 IEANRAGQRLLIANIALGDQLATVVEQLVD 320
Cdd:cd16172 232 LALEQRLQALMQNNLVLFTQLNQTVNALVD 261
|
|
| PRK10337 |
PRK10337 |
sensor protein QseC; Provisional |
626-824 |
3.75e-06 |
|
sensor protein QseC; Provisional
Pssm-ID: 182388 [Multi-domain] Cd Length: 449 Bit Score: 50.42 E-value: 3.75e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 626 ELREALAGAhldgKLQTEIGEIAD----MLQGNLDKVVQHGKRADSIVKNMLLHSRQGSGDHR----PIDINALVEESLN 697
Cdd:PRK10337 247 ELRSPLAAL----KVQTEVAQLSDddpqARKKALLQLHAGIDRATRLVDQLLTLSRLDSLDNLqdvaEIPLEDLLQSAVM 322
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 698 LAYHgaRAEKPGFNITLercfDQAAGEVDLFPQEITRVLL--NLISNGF-YAATkrkadanGGSYEPTLAATTknlgdsv 774
Cdd:PRK10337 323 DIYH--TAQQAGIDVRL----TLNAHPVIRTGQPLLLSLLvrNLLDNAIrYSPQ-------GSVVDVTLNARN------- 382
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 260177206 775 eIKIRDNGTGIPPEVKEKMFNPFFttKPAGE---GTGLGLSlshdiIVKQHAG 824
Cdd:PRK10337 383 -FTVRDNGPGVTPEALARIGERFY--RPPGQeatGSGLGLS-----IVRRIAK 427
|
|
| cpxA |
PRK09470 |
envelope stress sensor histidine kinase CpxA; |
776-832 |
6.90e-06 |
|
envelope stress sensor histidine kinase CpxA;
Pssm-ID: 236532 [Multi-domain] Cd Length: 461 Bit Score: 49.55 E-value: 6.90e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 260177206 776 IKIRDNGTGIPPEVKEKMFNPFFTTKPAGE----GTGLGLSLSHDIIvKQHAGSIEVDTKP 832
Cdd:PRK09470 386 ITVDDDGPGVPEEEREQIFRPFYRVDEARDresgGTGLGLAIVENAI-QQHRGWVKAEDSP 445
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
776-848 |
8.13e-06 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 49.64 E-value: 8.13e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 260177206 776 IKIRDNGTGIPPEVKEKMFNPFFTTKPAGEGTGLGLSLShDIIVKQHAGSIEVDTKPGEFTEFRIVLPRSAAT 848
Cdd:PRK15347 547 FTVEDTGCGIDIQQQQQIFTPFYQADTHSQGTGLGLTIA-SSLAKMMGGELTLFSTPGVGSCFSLVLPLNEYA 618
|
|
| PRK10549 |
PRK10549 |
two-component system sensor histidine kinase BaeS; |
600-832 |
8.79e-06 |
|
two-component system sensor histidine kinase BaeS;
Pssm-ID: 182539 [Multi-domain] Cd Length: 466 Bit Score: 49.25 E-value: 8.79e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 600 AGIAHEIKNPLnfvnnfsAVsveLIDELrEALAgahlDG----------KLQTEIGeiadmlqgNLDKVVQHgkradsiv 669
Cdd:PRK10549 245 ADISHELRTPL-------AV---LRGEL-EAIQ----DGvrkftpesvaSLQAEVG--------TLTKLVDD-------- 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 670 knmlLH----SRQGSGDHR--PIDINALVEESLNlAYHGARAEKpgfNITLERCFDQaagEVDLF--PQEITRVLLNLIS 741
Cdd:PRK10549 294 ----LHqlslSDEGALAYRktPVDLVPLLEVAGG-AFRERFASR---GLTLQLSLPD---SATVFgdPDRLMQLFNNLLE 362
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 742 NGFyaatkRKADANGGsyeptLAATTKNLGDSVEIKIRDNGTGIPPEVKEKMFNPFFTTKP----AGEGTGLGLSLSHDi 817
Cdd:PRK10549 363 NSL-----RYTDSGGS-----LHISAEQRDKTLRLTFADSAPGVSDEQLQKLFERFYRTEGsrnrASGGSGLGLAICLN- 431
|
250
....*....|....*
gi 260177206 818 IVKQHAGSIEVDTKP 832
Cdd:PRK10549 432 IVEAHNGRIIAAHSP 446
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
729-842 |
9.28e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 45.15 E-value: 9.28e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 729 PQEITRVLLNLISNGFyaatkRKADANGgsyepTLAATTKNLGDSVEIKIRDNGTGIPPEVKEKMFNPFFTTKP----AG 804
Cdd:cd16946 2 RDRLQQLFVNLLENSL-----RYTDTGG-----KLRIRAAQTPQEVRLDVEDSAPGVSDDQLARLFERFYRVESsrnrAS 71
|
90 100 110
....*....|....*....|....*....|....*...
gi 260177206 805 EGTGLGLSLSHDiIVKQHAGSIEVDtkPGEFTEFRIVL 842
Cdd:cd16946 72 GGSGLGLAICHN-IALAHGGTISAE--HSPLGGLRLVL 106
|
|
| HATPase_CreC-like |
cd16945 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
771-833 |
2.29e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CreC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli CreC of the CreC-CreB two-component regulatory system (TCS) involved in catabolic regulation. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and accessory sensory domain(s) such as HAMP, CACHE or PAS.
Pssm-ID: 340421 [Multi-domain] Cd Length: 106 Bit Score: 43.99 E-value: 2.29e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 260177206 771 GDSVEIKIRDNGTGIPPEVKEKMFNPFFTTKPAGEG---TGLGLSLSHDIIvKQHAGSIEVDTKPG 833
Cdd:cd16945 34 TEGIELLVFDEGSGIPDYALNRVFERFYSLPRPHSGqksTGLGLAFVQEVA-QLHGGRITLRNRPD 98
|
|
| HAMP |
COG2770 |
HAMP domain [Signal transduction mechanisms]; |
181-699 |
2.56e-05 |
|
HAMP domain [Signal transduction mechanisms];
Pssm-ID: 442051 [Multi-domain] Cd Length: 631 Bit Score: 47.80 E-value: 2.56e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 181 VLQLRNKIDAASNSQERQAAINRFELAADTLEQIEREASVVFEFLTRAANTEDTGLLQSQASDARNSVRALKGRIDDLER 260
Cdd:COG2770 50 LLLLLLLLLLLLAALVLLALLLAAALLLLLLLLSLVALAALLLALLLLLLLALLLLLAALLLLLLLAALALLLLLLLLLA 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 261 KLAEGLIDPTQRLNSIVTDVDGLFVTRTKEIEANRAGQRLLIANIALGDQLATVVEQLVDRARRDIDTATAQAYSVQTFG 340
Cdd:COG2770 130 ALLALLLALALLALLLGLAAARLLLAALLALAAALALALGAGELLLLADLAAAIAALLAALLLLLLGGLLLVVLLEAALA 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 341 GAVQLGVVALSLISSVLIVWLYVGRNIVARLMNLSGIMTAIAGGSRSVAVPVAGTDEIGAMGRAVEIFRRNAVDLDHLLA 420
Cdd:COG2770 210 ALLLLLLLALLALLLALLLALLLARRITRPLRRLAEAARRIAAGDLDVRIPVSRKDEIGELARAFNRMADSLRESIEEAE 289
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 421 ERAEAATRLERLVEERTRELAHRQAELRVTFDNMGDGVVMFNEEMRLAAWNRNLQEILDLPDSFFTEPRTYRDYIAYLIK 500
Cdd:COG2770 290 EEEELAEAELARLLEALLELLLALLLLLLALLLLAAAALLLELLLLLLLALLLLLLLAADLLLALALAALLLLLALELLL 369
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 501 HGEFGDVDLDAELQRQVEHADRQRRIERTRPDGRVLEIRVNPVPGGGFVAIYSDITERKKAEERVRAARDAAEAALRELK 580
Cdd:COG2770 370 EAELLVLLALEALALEAELAAVLALLAALAAALLLLELALEELVLALLALALLALAAAAAAAEAAAAALELAAAAIAAAA 449
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 581 AAQNRLVQAEKLASLGQLTAGIAHEIKNPLNFVNNFSAVSVELIDELREALAGAHLDGKLQTEIGEIADMLQGNLDKVVQ 660
Cdd:COG2770 450 AAEAEGGLAELEAEELVAAAEALLLLAALLLLAALGALELLLLEEEEEAGAAAEELAEELLLLEGLLLLLLLEAEALEVA 529
|
490 500 510
....*....|....*....|....*....|....*....
gi 260177206 661 HGKRADSIVKNMLLHSRQGSGDHRPIDINALVEESLNLA 699
Cdd:COG2770 530 EELLELEEAALLLAAAAELAALLALLLALAAVEAAALLL 568
|
|
| HATPase_VanS-like |
cd16923 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
734-843 |
4.70e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Enterococcus faecium VanS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Enterococcus faecium VanS HK of the VanS-VanR two-component regulatory system (TCS) which activates the transcription of vanH, vanA and vanX vancomycin resistance genes. It also contains Ecoli YedV and PcoS, probable members of YedW-YedV TCS and PcoS-PcoR TCS, repectively. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); most also have a HAMP sensor domain.
Pssm-ID: 340400 [Multi-domain] Cd Length: 102 Bit Score: 43.14 E-value: 4.70e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 734 RVLLNLISNGFYAatkrkadanggSYEPTLAATTKNL-GDSVEIKIRDNGTGIPPEVKEKMFNPFFTTKPA--GEGTGLG 810
Cdd:cd16923 3 RVFSNLLSNAIKY-----------SPENTRIYITSFLtDDVVNIMFKNPSSHPLDFKLEKLFERFYRGDNSrnTEGAGLG 71
|
90 100 110
....*....|....*....|....*....|...
gi 260177206 811 LSLSHDIIVkQHAGSIEVDTKpGEFTEFRIVLP 843
Cdd:cd16923 72 LSIAKAIIE-LHGGSASAEYD-DNHDLFKVRLP 102
|
|
| COG3920 |
COG3920 |
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction ... |
282-848 |
4.91e-05 |
|
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction mechanisms];
Pssm-ID: 443125 [Multi-domain] Cd Length: 495 Bit Score: 46.82 E-value: 4.91e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 282 GLFVTRTKEIEANRAGQRLLIANIALGDQLATVVEQLVDRARRDIDTATAQAYSVQTFGGAVQLGVVALSLISSVLIVWL 361
Cdd:COG3920 1 LLLALLLLLLLALAALLLLAALLLLAAALLLALLALLLLALLLLALLLASALLALLALSAAALAAALAVALAAAVGAAAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 362 YVGRNIVARLMNLSGIMTAIAGGSRSVAVPVAGTDEIGAMGRAVEIFRRNAVDLDHLLAERAEAATRLERLVEERTRELA 441
Cdd:COG3920 81 LLALLVLLLLLLLAAAALALALLLAALAGLLLLAALLLLRLVALLAALALLALLLLLLLLLAILALAELAVALAELAAAL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 442 HRQAELRVTFDNMGDGVVMFNEEMRLAAWNRNLQEILDLPDSFFTEPRTYRDYIAYLIKHGEFGDVDLDAELQRQVEHAD 521
Cdd:COG3920 161 LLLAEELAALRLAAAALLLLLAALLDLGLALAALAAAALLALLLALELLLALLLLLLLLLALLLVLLAALLRLRAAVLEE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 522 RQRRIERTRPDGRVLEIRVNPVPGGGF----VAIYSDITERKKAEERVraardaaeaalrELKAAQNRLVQAEklaslgq 597
Cdd:COG3920 241 LERRRRARGLGRLLLLLLLLLLLLRALlllaAGIRLVITERKRAEEEL------------EASLEEKELLLRE------- 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 598 ltagIAHEIKNplnfvnNFSAVSvelidelreALAGAHLDgklQTEIGEIADMLQGNLDKVvqhgkRADSIVKNMLLHSr 677
Cdd:COG3920 302 ----LHHRVKN------NLQVVS---------SLLRLQAR---RADDPEAREALEESQNRI-----QALALVHELLYQS- 353
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 678 qgsGDHRPIDINALVEESLNLAYHGARAEKPGFNITLErcfdqaagEVDLFPQEITRV--LLN-LISNGF-YAATKRKad 753
Cdd:COG3920 354 ---EDWEGVDLRDYLRELLEPLRDSYGGRGIRIELDGP--------DVELPADAAVPLglILNeLVTNALkHAFLSGE-- 420
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 754 anggsyEPTLAATTKNLGDSVEIKIRDNGTGIPPEVKEKmfnpffttkpagEGTGLGLSLSHdIIVKQHAGSIEVDTKPG 833
Cdd:COG3920 421 ------GGRIRVSWRREDGRLRLTVSDNGVGLPEDVDPP------------ARKGLGLRLIR-ALVRQLGGTLELDRPEG 481
|
570
....*....|....*
gi 260177206 834 efTEFRIVLPRSAAT 848
Cdd:COG3920 482 --TRVRITFPLAELA 494
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
729-850 |
8.39e-05 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 46.44 E-value: 8.39e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 729 PQEITRVLLNLISNGFyaatkRKADanggsyEPTLAATTKNLGDSVEIKIRDNGTGIPPEVKEKMFNPFFTTKPAGEGTG 808
Cdd:PRK11466 559 PRRIRQVITNLLSNAL-----RFTD------EGSIVLRSRTDGEQWLVEVEDSGCGIDPAKLAEIFQPFVQVSGKRGGTG 627
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 260177206 809 LGLSLSHDiIVKQHAGSIEVDTKPGEFTEFRIVLPRSAATIA 850
Cdd:PRK11466 628 LGLTISSR-LAQAMGGELSATSTPEVGSCFCLRLPLRVATAP 668
|
|
| phoR |
PRK11006 |
phosphate regulon sensor histidine kinase PhoR; |
436-843 |
1.30e-04 |
|
phosphate regulon sensor histidine kinase PhoR;
Pssm-ID: 182895 [Multi-domain] Cd Length: 430 Bit Score: 45.39 E-value: 1.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 436 RTRELAHRQAELRVTFDNMGDGVVMFNEEMRLAAWNRNLQEILDlpdsfFTEPRTYRDYIAYLIKHGEFgdvdldaelQR 515
Cdd:PRK11006 89 RRRELGNLIKRFRSGAESLPDAVVLTTEEGNIFWCNGLAQQLLG-----FRWPEDNGQNILNLLRYPEF---------TQ 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 516 QVEHADRQRRIERTRPDGRVLEIRVNPVPGGGFVAIYSDITERKKAEervraardaaeaalrelKAAQNrlvqaeklasl 595
Cdd:PRK11006 155 YLKTRDFSRPLTLVLNNGRHLEIRVMPYTEGQLLMVARDVTQMHQLE-----------------GARRN----------- 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 596 gqLTAGIAHEIKNPLNFVNNFsavsVELIDElrEALAGAHLDGKLQTeigeiadmlqgnldkVVQHGKRADSIVKNMLLH 675
Cdd:PRK11006 207 --FFANVSHELRTPLTVLQGY----LEMMQD--QPLEGALREKALHT---------------MREQTQRMEGLVKQLLTL 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 676 SRQGSGDHrpIDINALVEESLNLAYHGARAEKPG---FNITlercFDqaageVDlfpqEITRVLLN------LISNGFYA 746
Cdd:PRK11006 264 SKIEAAPT--IDLNEKVDVPMMLRVLEREAQTLSqgkHTIT----FE-----VD----NSLKVFGNedqlrsAISNLVYN 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 747 ATKRkadanggsyepTLAATT-----KNLGDSVEIKIRDNGTGIPPEVKEKMFNPFFTTKPAGE----GTGLGLSlshdi 817
Cdd:PRK11006 329 AVNH-----------TPEGTHitvrwQRVPQGAEFSVEDNGPGIAPEHIPRLTERFYRVDKARSrqtgGSGLGLA----- 392
|
410 420 430
....*....|....*....|....*....|
gi 260177206 818 IVKQ----HAGSIEVDTKPGEFTEFRIVLP 843
Cdd:PRK11006 393 IVKHalshHDSRLEIESEVGKGTRFSFVLP 422
|
|
| dpiB |
PRK15053 |
sensor histidine kinase DpiB; Provisional |
731-844 |
2.52e-04 |
|
sensor histidine kinase DpiB; Provisional
Pssm-ID: 185013 [Multi-domain] Cd Length: 545 Bit Score: 44.44 E-value: 2.52e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 731 EITRVLLNLISNGFYAATKrkADANGGSYEPTLAattkNLGDSVEIKIRDNGTGIPPEVKEKMFNPFFTTK---PAGEGT 807
Cdd:PRK15053 432 EFAAIVGNLLDNAFEASLR--SDEGNKIVELFLS----DEGDDVVIEVADQGCGVPESLRDKIFEQGVSTRadePGEHGI 505
|
90 100 110
....*....|....*....|....*....|....*..
gi 260177206 808 GLGLSLSHdiiVKQHAGSIEVDTKPGEFTEFRIVLPR 844
Cdd:PRK15053 506 GLYLIASY---VTRCGGVITLEDNDPCGTLFSIFIPK 539
|
|
| HATPase_c_5 |
pfam14501 |
GHKL domain; This family represents the structurally related ATPase domains of histidine ... |
729-836 |
4.25e-04 |
|
GHKL domain; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 433996 [Multi-domain] Cd Length: 102 Bit Score: 40.28 E-value: 4.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 729 PQEITRVLLNLISNGFYAATKRKADAnggsyEPTLAATTKNlgDSVEIKIrDNGtgIPPEVKEKMFnpFFTTKPAGEGTG 808
Cdd:pfam14501 3 DVDLCVIFGNLLDNAIEACSKIDDNR-----FIRLKIREKQ--NFLIIRI-ENT--YEGELKFEGK--LPSTKTKGDGHG 70
|
90 100
....*....|....*....|....*...
gi 260177206 809 LGLSlSHDIIVKQHAGSIEVDTKPGEFT 836
Cdd:pfam14501 71 IGLK-SIRRIVKKYGGNLSTEIENGIFT 97
|
|
| PRK15048 |
PRK15048 |
methyl-accepting chemotaxis protein II; Provisional |
253-414 |
4.47e-04 |
|
methyl-accepting chemotaxis protein II; Provisional
Pssm-ID: 185008 [Multi-domain] Cd Length: 553 Bit Score: 43.84 E-value: 4.47e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 253 GRIDDLERKLAEGLIDPTQRLNSivTDVDGLFVTRTKEIEaNRAGQRLlianialgDQLATVVEQLVdrarRDIDTATAQ 332
Cdd:PRK15048 121 RNIDEKYKNYYTALTELIDYLDY--GNTGAYFAQPTQGMQ-NAMGEAF--------AQYALSSEKLY----RDIVTDNAD 185
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 333 AYSVQTFggavQLGVVALSLISSVLIVWLYVGRNIVARLMNLSGIMTAIAGGSRSVAVPVAGTDEIGAMGRAVEIFRRNA 412
Cdd:PRK15048 186 DYRFAQW----QLAVIALVVVLILLVAWYGIRRMLLTPLAKIIAHIREIAGGNLANTLTIDGRSEMGDLAQSVSHMQRSL 261
|
..
gi 260177206 413 VD 414
Cdd:PRK15048 262 TD 263
|
|
| HATPase_SpaK_NisK-like |
cd16975 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
730-826 |
4.63e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK. SpaK is the histidine kinase (HK) of the SpaK-SpaR two-component regulatory system (TCS), which is involved in the regulation of the biosynthesis of lantibiotic subtilin. NisK is the HK of the NisK-NisR TCS, which is involved in the regulation of the biosynthesis of lantibiotic nisin. SpaK and NisK may function as membrane-associated protein kinases that phosphorylate SpaR and NisR, respectively, in response to environmental signals.
Pssm-ID: 340434 [Multi-domain] Cd Length: 107 Bit Score: 40.52 E-value: 4.63e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 730 QEITRVLLNLISNGF-YAATKRkadanggsyepTLAATTKNLGDSVEIKIRDNGTGIPPEVKEKMFNPFFTTKPA---GE 805
Cdd:cd16975 3 LLLSRALINIISNACqYAPEGG-----------TVSISIYDEEEYLYFEIWDNGHGFSEQDLKKALELFYRDDTSrrsGG 71
|
90 100
....*....|....*....|.
gi 260177206 806 GTGLGLSLShDIIVKQHAGSI 826
Cdd:cd16975 72 HYGMGLYIA-KNLVEKHGGSL 91
|
|
| HATPase_CheA-like |
cd16916 |
Histidine kinase-like ATPase domain of the chemotaxis protein histidine kinase CheA, and some ... |
736-843 |
7.28e-04 |
|
Histidine kinase-like ATPase domain of the chemotaxis protein histidine kinase CheA, and some hybrid sensor histidine kinases; This family includes the cytoplasmic histidine kinase (HK) CheA, a transmembrane receptor which, together with cytoplasmic adaptor protein (CheW), forms the lattice at the core of the chemosensory array that controls the cellular chemotaxis of motile bacteria and archaea. CheA forms a two-component signal transduction system (TCS) with the response regulator CheY. Proteins having this CheA-like HATPase domain generally also have a histidine-phosphotransfer domain, a histidine kinase homodimeric domain, and a regulatory domain; some are hybrid sensor histidine kinases as they contain a REC signal receiver domain.
Pssm-ID: 340393 [Multi-domain] Cd Length: 178 Bit Score: 41.41 E-value: 7.28e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 736 LLNLISNGFYAATKRKAD--ANGGSYEPTLAATTKNLGDSVEIKIRDNGTGIPPE-VKEK-------------------- 792
Cdd:cd16916 43 LTHLLRNAVDHGIEAPEErlAAGKPPEGTITLRAEHQGNQVVIEVSDDGRGIDREkIREKaierglitadeaatlsddev 122
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 260177206 793 ---MFNPFFTTKP-----AGEGTGLglslshDII---VKQHAGSIEVDTKPGEFTEFRIVLP 843
Cdd:cd16916 123 lnlIFAPGFSTAEqvtdvSGRGVGM------DVVkrsIESLGGTIEVESEPGQGTTFTIRLP 178
|
|
| HisKA |
smart00388 |
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine ... |
594-681 |
7.57e-04 |
|
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine kinases.
Pssm-ID: 214644 [Multi-domain] Cd Length: 66 Bit Score: 38.70 E-value: 7.57e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 594 SLGQLTAGIAHEIKNPLNFVNNFSavsvelidelrEALAGAHLDGKlQTEIgeiadmlqgnLDKVVQHGKRADSIVKNML 673
Cdd:smart00388 1 AKREFLANLSHELRTPLTAIRGYL-----------ELLLDTELSEE-QREY----------LETILREAERLLRLINDLL 58
|
....*...
gi 260177206 674 LHSRQGSG 681
Cdd:smart00388 59 DLSRIEAG 66
|
|
| HisKA |
pfam00512 |
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine ... |
594-681 |
9.20e-04 |
|
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine kinases.
Pssm-ID: 459839 [Multi-domain] Cd Length: 66 Bit Score: 38.35 E-value: 9.20e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 594 SLGQLTAGIAHEIKNPLNFVNNFSavsvelidelrEALagahLDGKLQTEIGEIadmlqgnLDKVVQHGKRADSIVKNML 673
Cdd:pfam00512 1 AKSEFLANLSHELRTPLTAIRGYL-----------ELL----RDEKLDEEQREY-------LETILRSAERLLRLINDLL 58
|
....*...
gi 260177206 674 LHSRQGSG 681
Cdd:pfam00512 59 DLSRIEAG 66
|
|
| HisKA |
cd00082 |
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed ... |
592-677 |
1.07e-03 |
|
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylation by the catalytic domain of the histidine kinase. They subsequently transfer the phosphoryl group to the Asp acceptor residue of a response regulator protein. Two-component signalling systems, consisting of a histidine protein kinase that senses a signal input and a response regulator that mediates the output, are ancient and evolutionarily conserved signaling mechanisms in prokaryotes and eukaryotes.
Pssm-ID: 119399 [Multi-domain] Cd Length: 65 Bit Score: 37.96 E-value: 1.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 592 LASLGQLTAGIAHEIKNPLNFVNNFSavsvelidelrEALAGAHLDGKLQTEIgeiadmlqgnLDKVVQHGKRADSIVKN 671
Cdd:cd00082 1 LQAKGEFLANVSHELRTPLTAIRGAL-----------ELLEEELLDDEEQREY----------LERIREEAERLLRLIND 59
|
....*.
gi 260177206 672 MLLHSR 677
Cdd:cd00082 60 LLDLSR 65
|
|
| HATPase_EcPhoR-like |
cd16952 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
775-845 |
1.13e-03 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoR; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli or Vibrio cholera PhoR, the histidine kinase (HK) of PhoB-PhoR a two-component signal transduction system (TCS) involved in phosphate regulation. PhoR monitors extracellular inorganic phosphate (Pi) availability and PhoB, the response regulator, regulates transcription of genes of the phosphate regulon. PhoR is a bifunctional histidine autokinase/phospho-PhoB phosphatase; in phosphate deficiency, it autophosphorylates and Pi is transferred to PhoB, and when environmental Pi is abundant, it removes the phosphoryl group from phosphorylated PhoB. Other roles of PhoB-PhoR TCS have been described, including motility, biofilm formation, intestinal colonization, and virulence in V. cholera. E.coli PhoR and Bacillus subtilis PhoR (whose HATPase domain belongs to a different family) sense very different signals in each bacterium. In E. coli the PhoR signal comes from phosphate transport mediated by the PstSCAB2 phosphate transporter and the PhoU chaperone-like protein while in B. subtilis, the PhoR activation signal comes from wall teichoic acid (WTA) metabolism.
Pssm-ID: 340428 [Multi-domain] Cd Length: 108 Bit Score: 39.49 E-value: 1.13e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 260177206 775 EIKIRDNGTGIPPEVKEKMFNPFFTTKPAGE----GTGLGLSLSHDIIVKqHAGSIEVDTKPGEFTEFRIVLPRS 845
Cdd:cd16952 34 RLSVEDTGPGIPPEHIPRLTERFYRVDIERCrntgGTGLGLAIVKHVMSR-HDARLLIASELGKGSRFTCLFPSS 107
|
|
| PRK10815 |
PRK10815 |
two-component system sensor histidine kinase PhoQ; |
771-832 |
2.09e-03 |
|
two-component system sensor histidine kinase PhoQ;
Pssm-ID: 182754 [Multi-domain] Cd Length: 485 Bit Score: 41.54 E-value: 2.09e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 260177206 771 GDSVEIKIRDNGTGIPPEVKEKMFN---PFFTTKPageGTGLGLSLSHDIIvKQHAGSIEVDTKP 832
Cdd:PRK10815 406 DEHLHIVVEDDGPGIPESKRELIFDrgqRADTLRP---GQGLGLSVAREIT-EQYEGKISAGDSP 466
|
|
| HATPase_SpoIIAB-like |
cd16942 |
Histidine kinase-like ATPase domain of SpoIIAB, an anti sigma-F factor and serine-protein ... |
772-836 |
2.24e-03 |
|
Histidine kinase-like ATPase domain of SpoIIAB, an anti sigma-F factor and serine-protein kinase involved in regulating sigma-F during sporulation in Bacilli, and related domains; This family includes histidine kinase-like ATPase (HATPase) domain of SpoIIAB, an anti sigma-F factor and a serine-protein kinase involved in regulating sigma-F during sporulation in Bacilli where, early in sporulation, the cell divides into two unequal compartments: a larger mother cell and a smaller forespore. Sigma-F transcription factor is activated in the forespore directly after the asymmetric septum forms, and its spatial and temporal activation is required for sporulation. Free sigma-F can associate with the RNA polymerase core and activate transcription of the sigma-F regulon, its regulation may comprise a partner-switching mechanism involving SpoIIAB, SpoIIAA, and sigma-F as follows: SpoIIAB can form alternative complexes with either: i) sigma-F, holding it in an inactive form and preventing its association with RNA polymerase, or ii) unphosphorylated SpoIIAA and a nucleotide, either ATP or ADP. In the presence of ATP, SpoIIAB acts as a kinase to specifically phosphorylate a serine residue of SpoIIAA; this phosphorylated form has low affinity for SpoIIAB and dissociates, making SpoIIAB available to capture sigma-F. SpoIIAA may then be dephosphorylated by a SpoIIE serine phosphatase and be free to attack the SpoIIAB sigma-F complex to induce the release of sigma-F.
Pssm-ID: 340418 [Multi-domain] Cd Length: 135 Bit Score: 39.06 E-value: 2.24e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 260177206 772 DSVEIKIRDNGTGIPpEVKEKMfNPFFTTKPAGEGTGLGLSlshdiIVKQHAGSIEVDTKPGEFT 836
Cdd:cd16942 72 GVVHLTVRDEGVGIP-DIEEAR-QPLFTTKPELERSGMGFT-----IMENFMDEVIVESEVNKGT 129
|
|
| HATPase_YpdA-YehU-LytS-like |
cd16924 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
771-843 |
3.37e-03 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli YpdA, YehU, Bacillus subtilis LytS, and some hybrid sensor histidine kinases; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis LytS, a HK of the two-component system (TCS) LytS-LytR needed for growth on pyruvate, and Staphylococcus aureus LytS-LytR TCS involved in the adaptation of S. aureus to cationic antimicrobial peptides. It also includes the HATPase domains of Escherichia coli YpdA and YehU, HKs of YpdA-YpdB and YehU-YehTCSs, which are involved together in a nutrient sensing regulatory network. Proteins having this HATPase domain also contain a histidine kinase domain (His-kinase), some having accessory sensor domain(s) such as Cache, HAMP or GAF; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340401 [Multi-domain] Cd Length: 103 Bit Score: 37.81 E-value: 3.37e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 260177206 771 GDSVEIKIRDNGTGIPPEVKEKMfnpfftTKPAGEGTGLGLSLSHDIIV----KQHAGSIEVDTKPGefTEFRIVLP 843
Cdd:cd16924 35 DNHVMIEVEDNGRGIDPKVLNIL------GKKPKEGNGIGLYNVHQRLIllfgEDYGIHIASEPDKG--TRITFTIP 103
|
|
| HATPase_PhoQ-like |
cd16954 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
774-842 |
4.10e-03 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG. PhoQ is the histidine kinase (HK) of the PhoP-PhoQ two-component regulatory system (TCS), which responds to the levels of Mg2+ and Ca2+, controls virulence, mediates the adaptation to Mg2+-limiting environments, and regulates numerous cellular activities. Providencia stuartii AarG is a putative sensor kinase which controls the expression of the 2'-N-acetyltransferase and an intrinsic multiple antibiotic resistance (Mar) response in Providencia stuartii. The AarG product is similar to PhoQ in that it is able to restore wild-type levels of resistance to a Salmonella typhimurium phoQ mutant. However, the expression of the 2'-N-acetyltransferase gene and of aarP (a gene encoding a transcriptional activator of 2'-N-acetyltransferase) are not significantly affected by the levels of Mg2+ or Ca2+. Most proteins in this group contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory HAMP sensor domain, and some have an intracellular membrane -interaction PhoQ sensor domain.
Pssm-ID: 340430 [Multi-domain] Cd Length: 135 Bit Score: 38.38 E-value: 4.10e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 260177206 774 VEIKIRDNGTGIPPEVKEKMF---NPFFTTKPageGTGLGLSLSHDIIvKQHAGSIEVDTKPGEFTEFRIVL 842
Cdd:cd16954 68 LHLIVDDDGPGVPESQRSKIFqrgQRLDEQRP---GQGLGLAIAKEIV-EQYGGELSLSDSPLGGARFEVVF 135
|
|
| HAMP |
smart00304 |
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; |
365-411 |
4.16e-03 |
|
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain;
Pssm-ID: 197640 [Multi-domain] Cd Length: 53 Bit Score: 36.07 E-value: 4.16e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 260177206 365 RNIVARLMNLSGIMTAIAGGSRSVAVPVAGTDEIGAMGRAVEIFRRN 411
Cdd:smart00304 1 RRLLRPLRRLAEAAQRIADGDLTVRLPVDGRDEIGELARAFNEMADR 47
|
|
| CheA |
COG0643 |
Chemotaxis protein histidine kinase CheA [Signal transduction mechanisms]; |
771-849 |
5.37e-03 |
|
Chemotaxis protein histidine kinase CheA [Signal transduction mechanisms];
Pssm-ID: 440408 [Multi-domain] Cd Length: 563 Bit Score: 40.17 E-value: 5.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 771 GDSVEIKIRDNGTGIPPE-VKEK-----------------------MFNPFFTTKP-----AGEGTGLglslshDIiVKQ 821
Cdd:COG0643 319 GGRVVIEVSDDGRGLDLEkIRAKaiekglitaeeaaalsdeellelIFAPGFSTAEevtdlSGRGVGM------DV-VKT 391
|
90 100 110
....*....|....*....|....*....|..
gi 260177206 822 HA----GSIEVDTKPGEFTEFRIVLPRSAATI 849
Cdd:COG0643 392 NIealgGTIEIESEPGKGTTFTLRLPLTLAII 423
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
347-447 |
8.70e-03 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 39.63 E-value: 8.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260177206 347 VVALSLISSVLIVWL--YVGRNIvARLMNlsgIMTAIAGGSRSVAVPVAGTDEIGAMGRAveifrrnavdLDHLLAERAE 424
Cdd:PRK15347 303 LLILVLLTSVLFLLLrrYLAKPL-WRFVD---IINKTGPAALEPRLPENRLDELGSIAKA----------YNQLLDTLNE 368
|
90 100
....*....|....*....|....*
gi 260177206 425 AATRLERLVEERTREL--AHRQAEL 447
Cdd:PRK15347 369 QYDTLENKVAERTQALaeAKQRAEQ 393
|
|
| |
