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Conserved domains on  [gi|297500151|gb|ADI43512|]
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anthranilate synthase, partial [Agrobacterium sp. AB35-9]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK13566 super family cl47121
anthranilate synthase component I;
1-170 4.09e-152

anthranilate synthase component I;


The actual alignment was detected with superfamily member PRK13566:

Pssm-ID: 481461 [Multi-domain]  Cd Length: 720  Bit Score: 436.66  E-value: 4.09e-152
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151   1 CPISGTIKRGDDPIADSEQILKLLNSKKDESELTMCSDVDRNDKSRVCEPGSVKVIGRRQIEMYSRLIHTVDHIEGRLRD 80
Cdd:PRK13566 325 CPISGTIKRGADAIGDAEQIRKLLNSKKDESELTMCTDVDRNDKSRVCEPGSVKVIGRRQIEMYSRLIHTVDHVEGRLRP 404

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151  81 DMDAFDGFLSHAWAVTVTGAPKLWAMRFIEGHEKSPRAWYGGAIGMVGFNGDMNTGLTLRTIRIKDGIAEVRAGATLLND 160
Cdd:PRK13566 405 GFDALDAFLTHAWAVTVTGAPKLWAMQFIEDHERSPRRWYGGAVGMVGFDGDMNTGLTLRTIRIKDGVAEVRVGATLLFD 484

                        170
                 ....*....|
gi 297500151 161 SNPQEEEAET 170
Cdd:PRK13566 485 SDPEAEEAET 494
 
Name Accession Description Interval E-value
PRK13566 PRK13566
anthranilate synthase component I;
1-170 4.09e-152

anthranilate synthase component I;


Pssm-ID: 237429 [Multi-domain]  Cd Length: 720  Bit Score: 436.66  E-value: 4.09e-152
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151   1 CPISGTIKRGDDPIADSEQILKLLNSKKDESELTMCSDVDRNDKSRVCEPGSVKVIGRRQIEMYSRLIHTVDHIEGRLRD 80
Cdd:PRK13566 325 CPISGTIKRGADAIGDAEQIRKLLNSKKDESELTMCTDVDRNDKSRVCEPGSVKVIGRRQIEMYSRLIHTVDHVEGRLRP 404

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151  81 DMDAFDGFLSHAWAVTVTGAPKLWAMRFIEGHEKSPRAWYGGAIGMVGFNGDMNTGLTLRTIRIKDGIAEVRAGATLLND 160
Cdd:PRK13566 405 GFDALDAFLTHAWAVTVTGAPKLWAMQFIEDHERSPRRWYGGAVGMVGFDGDMNTGLTLRTIRIKDGVAEVRVGATLLFD 484

                        170
                 ....*....|
gi 297500151 161 SNPQEEEAET 170
Cdd:PRK13566 485 SDPEAEEAET 494
TrpE-clade3 TIGR01815
anthranilate synthase, alpha proteobacterial clade; This model represents a small clade of ...
 1-170 8.14e-125

anthranilate synthase, alpha proteobacterial clade; This model represents a small clade of anthranilate synthases from alpha proteobacteria and Nostoc (a cyanobacterium). This enzyme is the first step in the pathway for the biosynthesis of tryprophan from chorismate. [Amino acid biosynthesis, Aromatic amino acid family]


Pssm-ID: 130874 [Multi-domain]  Cd Length: 717  Bit Score: 366.90  E-value: 8.14e-125
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151    1 CPISGTIKRGDDPIADSEQILKLLNSKKDESELTMCSDVDRNDKSRVCEPGSVKVIGRRQIEMYSRLIHTVDHIEGRLRD 80
Cdd:TIGR01815 315 CPISGTIARGADAIGDAAQILRLLNSAKDEAELTMCTDVDRNDKSRVCEPGSVKVIGRRQIELYSRLIHTVDHVEGRLRS 394

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151   81 DMDAFDGFLSHAWAVTVTGAPKLWAMRFIEGHEKSPRAWYGGAIGMVGFNGDMNTGLTLRTIRIKDGIAEVRAGATLLND 160
Cdd:TIGR01815 395 GMDALDAFLSHSWAVTVTGAPKRWAMQFIEDTEQSPRRWYGGAFGRLGFNGGMNTGLTLRTIRMADGIAEVRAGATLLYD 474

                         170
                  ....*....|
gi 297500151  161 SNPQEEEAET 170
Cdd:TIGR01815 475 SDPDAEEAET 484
Chorismate_bind pfam00425
chorismate binding enzyme; This family includes the catalytic regions of the chorismate ...
 2-170 2.21e-58

chorismate binding enzyme; This family includes the catalytic regions of the chorismate binding enzymes anthranilate synthase, isochorismate synthase, aminodeoxychorismate synthase and para-aminobenzoate synthase.


Pssm-ID: 425674 [Multi-domain]  Cd Length: 255  Bit Score: 182.75  E-value: 2.21e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151    2 PISGTIKRGDDPIADSEQILKLLNSKKDESELTMCSDVDRNDKSRVCEPGSVKVIGRRQIEMYSRLIHTVDHIEGRLRDD 81
Cdd:pfam00425  84 PIAGTRPRGKDPAEDEALAAELLADPKERAEHLMVVDLIRNDLGRVCVPGSVKVPELPEVERYGTVQHLVSTISGRLKPG 163

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151   82 MDAFDGFLSHAWAVTVTGAPKLWAMRFIEGHEKSPRAWYGGAIGMVGFNGDMNTGLTLRTIRIKDGIAEVRAGATLLNDS 161
Cdd:pfam00425 164 LSLLDLLKALFPTGAVTGAPKKRAMEIIRELEPFPRGLYAGAVGYLDPDGDADFAVAIRTALVDNGRARLYAGAGIVADS 243


                  ....*....
gi 297500151  162 NPQEEEAET 170
Cdd:pfam00425 244 DPEAEWEET 252
TrpE COG0147
Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism, ...
 2-170 1.32e-56

Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism, Coenzyme transport and metabolism]; Anthranilate/para-aminobenzoate synthases component I is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis


Pssm-ID: 439917 [Multi-domain]  Cd Length: 416  Bit Score: 182.61  E-value: 1.32e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151   2 PISGTIKRGDDPIADSEQILKLLNSKKDESELTMCsdVD--RNDKSRVCEPGSVKVIGRRQIEMYSRLIHTVDHIEGRLR 79
Cdd:COG0147  235 PIAGTRPRGATPEEDAALAEELLADEKERAEHLML--VDlaRNDLGRVCEPGSVKVPELMVVERYSHVMHLVSTVTGRLR 312

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151  80 DDMDAFDgFLSHAW-AVTVTGAPKLWAMRFIEGHEKSPRAWYGGAIGMVGFNGDMNTGLTLRTIRIKDGIAEVRAGATLL 158
Cdd:COG0147  313 PGLDALD-ALRATFpAGTLTGAPKIRAMEIIDELEPTRRGVYGGAVGYLSFDGNMDLAIAIRTAVVKDGRAYVQAGAGIV 391

                        170
                 ....*....|..
gi 297500151 159 NDSNPQEEEAET 170
Cdd:COG0147  392 ADSDPEAEYQET 403
 
Name Accession Description Interval E-value
PRK13566 PRK13566
anthranilate synthase component I;
1-170 4.09e-152

anthranilate synthase component I;


Pssm-ID: 237429 [Multi-domain]  Cd Length: 720  Bit Score: 436.66  E-value: 4.09e-152
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151   1 CPISGTIKRGDDPIADSEQILKLLNSKKDESELTMCSDVDRNDKSRVCEPGSVKVIGRRQIEMYSRLIHTVDHIEGRLRD 80
Cdd:PRK13566 325 CPISGTIKRGADAIGDAEQIRKLLNSKKDESELTMCTDVDRNDKSRVCEPGSVKVIGRRQIEMYSRLIHTVDHVEGRLRP 404

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151  81 DMDAFDGFLSHAWAVTVTGAPKLWAMRFIEGHEKSPRAWYGGAIGMVGFNGDMNTGLTLRTIRIKDGIAEVRAGATLLND 160
Cdd:PRK13566 405 GFDALDAFLTHAWAVTVTGAPKLWAMQFIEDHERSPRRWYGGAVGMVGFDGDMNTGLTLRTIRIKDGVAEVRVGATLLFD 484

                        170
                 ....*....|
gi 297500151 161 SNPQEEEAET 170
Cdd:PRK13566 485 SDPEAEEAET 494
TrpE-clade3 TIGR01815
anthranilate synthase, alpha proteobacterial clade; This model represents a small clade of ...
 1-170 8.14e-125

anthranilate synthase, alpha proteobacterial clade; This model represents a small clade of anthranilate synthases from alpha proteobacteria and Nostoc (a cyanobacterium). This enzyme is the first step in the pathway for the biosynthesis of tryprophan from chorismate. [Amino acid biosynthesis, Aromatic amino acid family]


Pssm-ID: 130874 [Multi-domain]  Cd Length: 717  Bit Score: 366.90  E-value: 8.14e-125
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151    1 CPISGTIKRGDDPIADSEQILKLLNSKKDESELTMCSDVDRNDKSRVCEPGSVKVIGRRQIEMYSRLIHTVDHIEGRLRD 80
Cdd:TIGR01815 315 CPISGTIARGADAIGDAAQILRLLNSAKDEAELTMCTDVDRNDKSRVCEPGSVKVIGRRQIELYSRLIHTVDHVEGRLRS 394

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151   81 DMDAFDGFLSHAWAVTVTGAPKLWAMRFIEGHEKSPRAWYGGAIGMVGFNGDMNTGLTLRTIRIKDGIAEVRAGATLLND 160
Cdd:TIGR01815 395 GMDALDAFLSHSWAVTVTGAPKRWAMQFIEDTEQSPRRWYGGAFGRLGFNGGMNTGLTLRTIRMADGIAEVRAGATLLYD 474

                         170
                  ....*....|
gi 297500151  161 SNPQEEEAET 170
Cdd:TIGR01815 475 SDPDAEEAET 484
Chorismate_bind pfam00425
chorismate binding enzyme; This family includes the catalytic regions of the chorismate ...
 2-170 2.21e-58

chorismate binding enzyme; This family includes the catalytic regions of the chorismate binding enzymes anthranilate synthase, isochorismate synthase, aminodeoxychorismate synthase and para-aminobenzoate synthase.


Pssm-ID: 425674 [Multi-domain]  Cd Length: 255  Bit Score: 182.75  E-value: 2.21e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151    2 PISGTIKRGDDPIADSEQILKLLNSKKDESELTMCSDVDRNDKSRVCEPGSVKVIGRRQIEMYSRLIHTVDHIEGRLRDD 81
Cdd:pfam00425  84 PIAGTRPRGKDPAEDEALAAELLADPKERAEHLMVVDLIRNDLGRVCVPGSVKVPELPEVERYGTVQHLVSTISGRLKPG 163

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151   82 MDAFDGFLSHAWAVTVTGAPKLWAMRFIEGHEKSPRAWYGGAIGMVGFNGDMNTGLTLRTIRIKDGIAEVRAGATLLNDS 161
Cdd:pfam00425 164 LSLLDLLKALFPTGAVTGAPKKRAMEIIRELEPFPRGLYAGAVGYLDPDGDADFAVAIRTALVDNGRARLYAGAGIVADS 243


                  ....*....
gi 297500151  162 NPQEEEAET 170
Cdd:pfam00425 244 DPEAEWEET 252
TrpE COG0147
Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism, ...
 2-170 1.32e-56

Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism, Coenzyme transport and metabolism]; Anthranilate/para-aminobenzoate synthases component I is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis


Pssm-ID: 439917 [Multi-domain]  Cd Length: 416  Bit Score: 182.61  E-value: 1.32e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151   2 PISGTIKRGDDPIADSEQILKLLNSKKDESELTMCsdVD--RNDKSRVCEPGSVKVIGRRQIEMYSRLIHTVDHIEGRLR 79
Cdd:COG0147  235 PIAGTRPRGATPEEDAALAEELLADEKERAEHLML--VDlaRNDLGRVCEPGSVKVPELMVVERYSHVMHLVSTVTGRLR 312

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151  80 DDMDAFDgFLSHAW-AVTVTGAPKLWAMRFIEGHEKSPRAWYGGAIGMVGFNGDMNTGLTLRTIRIKDGIAEVRAGATLL 158
Cdd:COG0147  313 PGLDALD-ALRATFpAGTLTGAPKIRAMEIIDELEPTRRGVYGGAVGYLSFDGNMDLAIAIRTAVVKDGRAYVQAGAGIV 391

                        170
                 ....*....|..
gi 297500151 159 NDSNPQEEEAET 170
Cdd:COG0147  392 ADSDPEAEYQET 403
PRK13571 PRK13571
anthranilate synthase component I; Provisional
 2-170 2.48e-46

anthranilate synthase component I; Provisional


Pssm-ID: 184152 [Multi-domain]  Cd Length: 506  Bit Score: 157.88  E-value: 2.48e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151   2 PISGTIKRGDDPIADSEQILKLLNSKKDESELTMCSDVDRNDKSRVCEPGSVKVIGRRQIEMYSRLIHTVDHIEGRLRDD 81
Cdd:PRK13571 317 PIAGTRWRGATPEEDALLEKELLADPKERAEHLMLVDLGRNDLGRVCRPGTVRVVDFSHIERYSHVMHLVSTVTGELAEG 396

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151  82 MDAFDGFLSHAWAVTVTGAPKLWAMRFIEGHEKSPRAWYGGAIGMVGFNGDMNTGLTLRTIRIKDGIAEVRAGATLLNDS 161
Cdd:PRK13571 397 RTALDAVTACFPAGTLSGAPKVRAMELIEELEPTRRGLYGGVVGYLDFAGDADTAIAIRTALMRDGTAYVQAGGGVVADS 476


                 ....*....
gi 297500151 162 NPQEEEAET 170
Cdd:PRK13571 477 DPDYEDNEA 485
PabB-clade2 TIGR01824
aminodeoxychorismate synthase, component I, clade 2; This clade of sequences is more closely ...
 2-170 3.51e-38

aminodeoxychorismate synthase, component I, clade 2; This clade of sequences is more closely related to TrpE (anthranilate synthase, TIGR00564/TIGR01820/TIGR00565) than to the better characterized group of PabB enzymes (TIGR00553/TIGR01823). This clade includes one characterized enzyme from Lactococcus and the conserved function across the clade is supported by these pieces of evidence: 1) all genomes with a member in this clade also have a separate TrpE gene, 2) none of these genomes contain an aparrent PabB from any of the other PabB clades, 3) none of these sequences are found in a region of the genome in association with other Trp biosynthesis genes, 4) all of these genomes aparrently contain most if not all of the steps of the folate biosynthetic pathway (for which PABA is a precursor). Many of the sequences hit by this model are annotated as TrpE enzymes, however, we believe that all members of this clade are, in fact, PabB. The sequences from Bacillus halodurans and subtilus which score below the trusted cutoff for this model are also likely to be PabB enzymes, but are too closely related to TrpE to be separated at this time.


Pssm-ID: 130883  Cd Length: 355  Bit Score: 133.36  E-value: 3.51e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151    2 PISGTIKRGDDPIADSEQILKLLNSKKDESELTMCSDVDRNDKSRVCEPGSVKVIGRRQIEMYSRLIHTVDHIEGRLRDD 81
Cdd:TIGR01824 180 PIAGTRPRGATLAEDGALAAELLQHDKDRAEHVMIVDLERNDLGRVCATGTVRVPELCAVESYSHVHHLVSRVTGRLREG 259

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151   82 MDAFDGFLSHAWAVTVTGAPKLWAMRFIEGHEKSPRAWYGGAIGMVGFNGDMNTGLTLRTIRIKDGIAEVRAGATLLNDS 161
Cdd:TIGR01824 260 AGLADLIRALFPGGSITGAPKVRAMEIIDELEPQPRGPYTGSVGWIDADGNADLNILIRTLEGGGAQLHFRTGAGIVADS 339


                  ....*....
gi 297500151  162 NPQEEEAET 170
Cdd:TIGR01824 340 DPAGEWDET 348
PRK13572 PRK13572
anthranilate synthase component I; Provisional
 2-170 1.27e-37

anthranilate synthase component I; Provisional


Pssm-ID: 237432 [Multi-domain]  Cd Length: 435  Bit Score: 133.71  E-value: 1.27e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151   2 PISGTIKRGDDPIADSEQILKLLNSKKDESELTMCSDVDRNDKSRVCEPGSVKVIGRRQIEMYSRLIHTVDHIEGRLRDD 81
Cdd:PRK13572 253 PIAGTAPRGKTEEEDKKLAEALLSDEKERAEHVMLVDLARNDVRKVSKSGSVRLERFFDVVKYSHVQHIESEVVGELKED 332

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151  82 MDAFDGFLSHAWAVTVTGAPKLWAMRFIEGHEKSPRAWYGGAIGMVGFNGDMNTGLTLRTIRIkDGIAEVRAGATLLNDS 161
Cdd:PRK13572 333 STMFDAIEAAFPAGTLTGAPKFRAMEIIDELEKSRRKVYGGAVGYFSNSGNADLAIAIRMAEI-DKVCRVRAGAGIVADS 411


                 ....*....
gi 297500151 162 NPQEEEAET 170
Cdd:PRK13572 412 VPEKEFYET 420
PRK13564 PRK13564
anthranilate synthase component 1;
2-170 1.25e-36

anthranilate synthase component 1;


Pssm-ID: 237428 [Multi-domain]  Cd Length: 520  Bit Score: 132.27  E-value: 1.25e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151   2 PISGTIKRGDDP---I---ADSEQILKLLNSKKDESELTMCSDVDRNDKSRVCEPGSVKVIGRRQIEMYSRLIHTVDHIE 75
Cdd:PRK13564 325 PIAGTRPRGRRAdgsIdrdLDSRIELELRTDHKELAEHLMLVDLARNDLARICQPGSRYVADLLKVDRYSHVMHLVSRVV 404

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151  76 GRLRDDMDAFdgflsHAW-----AVTVTGAPKLWAMRFIEGHEKSPRAWYGGAIGMVGFNGDMNTGLTLRTIRIKDGIAE 150
Cdd:PRK13564 405 GELRHDLDAL-----HAYracmnMGTLTGAPKVRAMQLIREVEGQRRGSYGGAVGYLTGHGDLDTCIVIRSAFVENGIAT 479

                        170       180
                 ....*....|....*....|
gi 297500151 151 VRAGATLLNDSNPQEEEAET 170
Cdd:PRK13564 480 VQAGAGVVLDSDPQSEADET 499
PRK13574 PRK13574
anthranilate synthase component I; Provisional
 2-170 1.66e-35

anthranilate synthase component I; Provisional


Pssm-ID: 184155 [Multi-domain]  Cd Length: 420  Bit Score: 127.63  E-value: 1.66e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151   2 PISGTIKRGDDPIADSEQILKLLNSKKDESELTMCSDVDRNDKSRVCEPGSVKVIGRRQIEMYSRLIHTVDHIEGRLRDD 81
Cdd:PRK13574 239 PIAGTRPRGSDQEEDLKLELELMNSEKDKAEHLMLVDLARNDLGKVCVPGTVRVPELMYVEKYSHVQHIVSKVIGTLKKK 318

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151  82 MDAFDGFLSHAWAVTVTGAPKLWAMRFIEGHEKSPRAWYGGAIGMVGFNGDMNTGLTLRTIRIKDGIAEVRAGATLLNDS 161
Cdd:PRK13574 319 YNALDVLKATFPAGTVSGAPKPMAMNIIETLEEYKRGPYAGAVGFISADGNAEFAIAIRTAFLNKDLLRIQAGAGIVYDS 398


                 ....*....
gi 297500151 162 NPQEEEAET 170
Cdd:PRK13574 399 NPESEYFET 407
PLN02445 PLN02445
anthranilate synthase component I
 2-170 2.97e-35

anthranilate synthase component I


Pssm-ID: 215244 [Multi-domain]  Cd Length: 523  Bit Score: 128.26  E-value: 2.97e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151   2 PISGTIKRGDDPIADSEQILKLLNSKKDESELTMCSDVDRNDKSRVCEPGSVKVIGRRQIEMYSRLIHTVDHIEGRLRDD 81
Cdd:PLN02445 317 PLAGTRRRGKTPEEDKALEKDLLADEKQCAEHIMLVDLGRNDVGKVSKAGSVKVEKLMNIERYSHVMHISSTVTGELLDH 396

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151  82 MDAFDGfLSHAWAV-TVTGAPKLWAMRFIEGHEKSPRAWYGGAIGMVGFNGDMNTGLTLRTIRIKDG------------- 147
Cdd:PLN02445 397 LTSWDA-LRAALPVgTVSGAPKVRAMELIDELEVTRRGPYSGGFGGVSFTGDMDIALALRTMVFPTAarydtmysykdtn 475

                        170       180
                 ....*....|....*....|....*...
gi 297500151 148 -----IAEVRAGATLLNDSNPQEEEAET 170
Cdd:PLN02445 476 srrewVAHLQAGAGIVADSDPEDEYREC 503
PRK09070 PRK09070
aminodeoxychorismate synthase component I;
2-170 1.04e-32

aminodeoxychorismate synthase component I;


Pssm-ID: 236371 [Multi-domain]  Cd Length: 447  Bit Score: 120.58  E-value: 1.04e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151   2 PISGTIKRGDDPiADSEQILKLLNSKKDESELTMCSDVDRNDKSRVCEPGSVKVIGRRQIEMYSRLIHTVDHIEGRLRDD 81
Cdd:PRK09070 266 PIAGTRPRFAGD-DDAALIRELVGHPKERAEHVMLIDLERNDLGRICAPGSVEVDELMTVESYAHVHHIVSNVRGRLRDG 344

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151  82 MDAFDGFLSHAWAVTVTGAPKLWAMRFIEGHEKSPRAWYGGAIGMVGFNGDMNTGLTLRTIRIKDGIAEVRAGATLLNDS 161
Cdd:PRK09070 345 VTPGEVIRAVFPGGTITGCPKVRCMQIIAELEQTPRGAYTGSFGYLNRDGDMDLNILIRTAEVQGNQVRFRTGAGIVVDS 424


                 ....*....
gi 297500151 162 NPQEEEAET 170
Cdd:PRK09070 425 DPERELDET 433
PLN02889 PLN02889
oxo-acid-lyase/anthranilate synthase
 2-169 1.97e-32

oxo-acid-lyase/anthranilate synthase


Pssm-ID: 215481 [Multi-domain]  Cd Length: 918  Bit Score: 121.88  E-value: 1.97e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151   2 PISGTIKRGDDPIADSEQILKLLNSKKDESELTMCSDVDRNDKSRVCEPGSVKVIGRRQIEMYSRlIHT-VDHIEGRLRD 80
Cdd:PLN02889 729 PIKGTIARGSTPEEDEQLKLQLQYSEKDQAENLMIVDLLRNDLGRVCEPGSVHVPNLMDVESYTT-VHTmVSTIRGKKRS 807

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151  81 DMDAFDGFLSHAWAVTVTGAPKLWAMRFIEGHEKSPRAWYGGAIGMVGFNGDMNTGLTLRTIRIKDGIAEVRAGATLLND 160
Cdd:PLN02889 808 NMSPVDCVRAAFPGGSMTGAPKLRSMELLDSLESSSRGIYSGSIGFFSYNQTFDLNIVIRTVVIHEGEASIGAGGAIVAL 887


                 ....*....
gi 297500151 161 SNPQEEEAE 169
Cdd:PLN02889 888 SNPEDEYEE 896
pabB PRK15465
aminodeoxychorismate synthase component 1;
2-170 1.97e-32

aminodeoxychorismate synthase component 1;


Pssm-ID: 185362 [Multi-domain]  Cd Length: 453  Bit Score: 120.02  E-value: 1.97e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151   2 PISGTIKRGDDPIADSEQILKLLNSKKDESELTMCSDVDRNDKSRVCEPGSVKVIGRRQIEMYSRLIHTVDHIEGRLRDD 81
Cdd:PRK15465 272 PIKGTLPRLPDPQEDSKQAEKLANSAKDRAENLMIVDLMRNDIGRVAVAGSVKVPELFVVEPFPAVHHLVSTITARLPEQ 351

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151  82 MDAFDGFLSHAWAVTVTGAPKLWAMRFIEGHEKSPRAWYGGAIGMVGFNGDMNTGLTLRTIRIKDGIAEVRAGATLLNDS 161
Cdd:PRK15465 352 LHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSFCGNMDTSITIRTLTAINGQIYCSAGGGIVADS 431


                 ....*....
gi 297500151 162 NPQEEEAET 170
Cdd:PRK15465 432 QEEAEYQET 440
PRK07508 PRK07508
aminodeoxychorismate synthase component I;
2-169 4.40e-31

aminodeoxychorismate synthase component I;


Pssm-ID: 236035 [Multi-domain]  Cd Length: 378  Bit Score: 115.11  E-value: 4.40e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151   2 PISGTIKRGDDPIADSEQILKLLNSKKDESELTMCSDVDRNDKSRVCEPGSVKVIGRRQIEMYSRLIHTVDHIEGRLRDD 81
Cdd:PRK07508 194 PMKGTAPRGATPAEDARLRAALLNDEKNQAENRMIVDLLRNDISRISEVGSLDVPELFDIETYPTVHQMVSRVRARLLPG 273

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151  82 MDAFDGFLSHAWAVTVTGAPKLWAMRFIEGHEKSPRAWYGGAIGMVGFNGDMNTGLTLRTIRI-KDGIAEVRAGATLLND 160
Cdd:PRK07508 274 LGLADIFAALFPCGSITGAPKIRAMEILRELEPGPRDLYCGAIGWIAPDGRMRFNVAIRTLSLfPGGRAVFNVGGGIVFD 353


                 ....*....
gi 297500151 161 SNPQEEEAE 169
Cdd:PRK07508 354 STAEAEYEE 362
PRK06404 PRK06404
anthranilate synthase component I; Reviewed
 2-169 3.27e-30

anthranilate synthase component I; Reviewed


Pssm-ID: 102361 [Multi-domain]  Cd Length: 351  Bit Score: 112.27  E-value: 3.27e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151   2 PISGTIkrgDDPIADSEqilkLLNSKKDESELTMCSDVDRNDKSRVCEPGSVKVIGRRQIEMYSRLIHTVDHIEGRLrDD 81
Cdd:PRK06404 184 PIAGTY---DDKILSNE----LLNSEKDKLEHRMLLDLARNDLSKFADIGTLNVDKVMKIEEFSSVKHLVSQVTAKF-SN 255

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151  82 MDAFDGFLSHAWAVTVTGAPKLWAMRFIEGHEKSPRAWYGGAIGMVGfNGDMNTGLTLRTIRIKDGIAEVRAGATLLNDS 161
Cdd:PRK06404 256 ASYRDILASMFPAGTVSGSPKERAIEIINKYEETPRGPYGGAIGIIS-KGYTDMALVIRTAYSHGNGFRVRAGAGIVKDS 334


                 ....*...
gi 297500151 162 NPQEEEAE 169
Cdd:PRK06404 335 DPEDEVNE 342
PRK05940 PRK05940
anthranilate synthase component I;
2-170 7.17e-29

anthranilate synthase component I;


Pssm-ID: 235651 [Multi-domain]  Cd Length: 463  Bit Score: 110.20  E-value: 7.17e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151   2 PISGTIKRGDDPIADSEQILKLLNSKKDESELTMCSDVDRNDKSRVCEPGSVKVIGRRQIEMYSRLIHTVDHIEGRLRDD 81
Cdd:PRK05940 271 PIAGTRPRGKTPAEDQQLAEELLSNIKERAEHIMLVDLERNDLGRVCQWGSVEVDELLTIERYSHVIHLVSNVVGTLQPN 350

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151  82 MDAFDGFLSHAWAVTVTGAPKLWAMRFIEGHEKSPRAWYGGAIGMVGFNGDMNTGLTLRTI---RIKDGIAEV--RAGAT 156
Cdd:PRK05940 351 RDAIDLIRALFPGGTITGCPKVRCMEIIEELEPVRRNLFYGSCGYLDQRGNLDLNILIRTLlytPLSRGLSTIwgQVGAG 430

                        170
                 ....*....|....
gi 297500151 157 LLNDSNPQEEEAET 170
Cdd:PRK05940 431 IVADSDPEKEWLES 444
PRK13567 PRK13567
anthranilate synthase component I; Provisional
 2-170 9.52e-29

anthranilate synthase component I; Provisional


Pssm-ID: 184148 [Multi-domain]  Cd Length: 468  Bit Score: 110.23  E-value: 9.52e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151   2 PISGTIKRGDDPIADSEQILKLLNSKKDESELTMCSDVDRNDKSRVCEPGSVKVIGRRQIEMYSRLIHTVDHIEGRLRDD 81
Cdd:PRK13567 288 PIAGTIQRGETTQIDNENMKQLLNDPKECSEHRMLVDLGRNDIHRVSKIGTSKITKLMVIEKYEHVMHIVSEVTGKINQN 367

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151  82 MDAFDGFLSHAWAVTVTGAPKLWAMRFIegHEKSP--RAWYGGAIGMVGFNGDMNTGLTLRTIRIKDGIAEVRAGATLLN 159
Cdd:PRK13567 368 LSPMTVIANLLPTGTVSGAPKLRAIERI--YEQYPhkRGVYSGGVGYINCNHNLDFALAIRTMMIDEQYINVEAGCGVVY 445

                        170
                 ....*....|.
gi 297500151 160 DSNPQEEEAET 170
Cdd:PRK13567 446 DSIPEKELNET 456
PRK05877 PRK05877
aminodeoxychorismate synthase component I; Provisional
 2-169 2.97e-19

aminodeoxychorismate synthase component I; Provisional


Pssm-ID: 235634 [Multi-domain]  Cd Length: 405  Bit Score: 83.21  E-value: 2.97e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151   2 PISGTIKRGDDPIAdseqilkLLNSKKDESELTMCSDVDRNDKSRVCEPGSVKVIGRRQIEMYSRLIHTVDHIEGRLRDD 81
Cdd:PRK05877 223 PIKGTLPLDADPSA-------LRASAKDVAENIMIVDLVRNDLGRVARTGTVTVPELLVVRPAPGVWHLVSTVSAQVPDE 295

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151  82 MDAFDgFLSHAWA-VTVTGAPKLWAMRFIEGHEKSPRAWYGGAIGMVGFNGDMNTGLTLRTIRIK-DGIAEVRAGATLLN 159
Cdd:PRK05877 296 LPMSD-LLDATFPpASVTGTPKLRARELISQWEPVRRGIYCGTVGLASPVAGCELNVAIRTVEFDaDGNAVLGVGGGITA 374

                        170
                 ....*....|
gi 297500151 160 DSNPQEEEAE 169
Cdd:PRK05877 375 DSDPDAEWQE 384
MenF COG1169
Isochorismate synthase EntC [Coenzyme transport and metabolism, Secondary metabolites ...
 2-170 3.31e-16

Isochorismate synthase EntC [Coenzyme transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism]; Isochorismate synthase EntC is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440783 [Multi-domain]  Cd Length: 353  Bit Score: 74.42  E-value: 3.31e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151   2 PISGTIKRGDDPIADSEQILKLLNSKKD--ESELTmcsdVD--RNDKSRVCEpgSVKVIGRRQIemySRLiHTVDH---- 73
Cdd:COG1169  173 ALAGTAPRGADPEEDAALAAALLASEKDrrEHALV----VDsiREALAPLCS--SLDVPEEPEL---LRL-RNVQHlatp 242

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151  74 IEGRLRDDMDAFDgfLSHAWAVT--VTGAPKLWAMRFIEGHEKSPRAWYGGAIGMVGFNGDMNTGLTLRTIRIKDGIAEV 151
Cdd:COG1169  243 ITGTLDPGVSALD--LAAALHPTpaVGGTPREAALALIRELEPFDRGWYAGPVGWVDADGDGEFAVAIRSALIDGNRARL 320

                        170
                 ....*....|....*....
gi 297500151 152 RAGATLLNDSNPQEEEAET 170
Cdd:COG1169  321 FAGAGIVAGSDPEAEWAET 339
PRK06772 PRK06772
salicylate synthase;
2-170 2.21e-14

salicylate synthase;


Pssm-ID: 102546 [Multi-domain]  Cd Length: 434  Bit Score: 69.76  E-value: 2.21e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151   2 PISGTIKRGDDPIADSEQILKLLNSKKDESELTMCSDVDRNDKSRVCEPGSVKVIGRRQIEMYSRLIHTVDHIEGRLRDD 81
Cdd:PRK06772 254 PLAGTRDRMGNPEHNKAKEAELLHDSKEVLEHILSVKEAIAELEAVCQPGSVVVEDLMSVRQRGSVQHLGSGVSGQLAEN 333

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151  82 MDAFDGFLSHAWAVTVTGAPKLWAMRFIEGHEKSPRAWYGGAIGMVGfNGDMNTGLTLRTIRIKDGIAEVRAGATLLNDS 161
Cdd:PRK06772 334 KDAWDAFTVLFPSITASGIPKNAALNAIMQIEKTPRELYSGAILLLD-DTRFDAALVLRSVFQDSQRCWIQAGAGIIAQS 412


                 ....*....
gi 297500151 162 NPQEEEAET 170
Cdd:PRK06772 413 TPERELTET 421
PRK07912 PRK07912
salicylate synthase;
45-170 3.93e-14

salicylate synthase;


Pssm-ID: 169151 [Multi-domain]  Cd Length: 449  Bit Score: 69.05  E-value: 3.93e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151  45 SRVCEPGSVKVIGRRQIEMYSRLIHTVDHIEGRLRDDMDAFDGFLSHAWAVTVTGAPKLWAMRFIEGHEKSPRAWYGGAI 124
Cdd:PRK07912 309 TEIAEPGSAAVIDFMTVRERGSVQHLGSTVRGRLDASSDRMDALEALFPAVTASGIPKAAGVDAIFRLDEAPRGLYSGAV 388

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 297500151 125 GMVGFNGDMNTGLTLRTIRIKDGIAEVRAGATLLNDSNPQEEEAET 170
Cdd:PRK07912 389 VMLSADGGLDAALTLRAAYQVGGRTWLRAGAGIIEESEPEREFEET 434
PRK07054 PRK07054
isochorismate synthase;
3-170 1.32e-13

isochorismate synthase;


Pssm-ID: 235920 [Multi-domain]  Cd Length: 475  Bit Score: 67.48  E-value: 1.32e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151   3 ISGTIKRGDDPIADSEQILKLLNSKKDESELTMCSDVDRNDKSRVCEpgSVKVIGRRQIEMYSRLIHTVDHIEGRLRDDM 82
Cdd:PRK07054 279 LAGTIARGADPAEDARLGAALMASAKDRLEHALVVDAIRAALAPLSR--ALDIPDQPSLHRLPRLQHLSTPIRATLAPDA 356

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151  83 DAFDGFLSHAWAVTVTGAPKLWAMRFIEGHEKSPRAWYGGAIGMVGFNGDMNTGLTLRTIRIKDGIAEVRAGATLLNDSN 162
Cdd:PRK07054 357 TLLQVVAALHPTPAVGGHPRAAALDYIRAHEGFDRGWYAAPIGWLDAHGNGDFAVALRSALITGGACRLFAGCGIVADSE 436


                 ....*...
gi 297500151 163 PQEEEAET 170
Cdd:PRK07054 437 PASEYRET 444
PLN02786 PLN02786
isochorismate synthase
 3-169 2.56e-10

isochorismate synthase


Pssm-ID: 178383 [Multi-domain]  Cd Length: 533  Bit Score: 57.87  E-value: 2.56e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151   3 ISGTIKRGDDPIADSEQILKLLNSKKDESELTMCSDVDRNDKSRVCEpgSVKVIGRRQIEMYSRLIHTVDHIEGRLRDDM 82
Cdd:PLN02786 347 LAATRPRGGSSARDLQIELDLLTSPKDDLEFSIVRENIREKLEAICD--RVVVEPHKAIRKLARVQHLYAQLAGRLRSED 424

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151  83 DAFDGFLSHAWAVTVTGAPKLWAMRFIEGHEKSPRAWYGGAIGMVGfNGDMNTGLTLRTIRIKDGI-AEVRAGATLLNDS 161
Cdd:PLN02786 425 DEFDILAALHPTPAVCGHPTEEARLLIAETESFDRGMYAGPVGWFG-GGESEFAVGIRSALVEKGLgALIYAGTGIVEGS 503


                 ....*...
gi 297500151 162 NPQEEEAE 169
Cdd:PLN02786 504 NPSSEWNE 511
PRK07093 PRK07093
para-aminobenzoate synthase component I; Validated
 2-166 6.88e-10

para-aminobenzoate synthase component I; Validated


Pssm-ID: 235932 [Multi-domain]  Cd Length: 323  Bit Score: 56.42  E-value: 6.88e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151   2 PISGTIkrgDDPIADSEQilKLLNSKKDESELTMCSDVDRNDKSRVCEpgSVKVIGRRQIEMYS----RLIHTVDHIEGR 77
Cdd:PRK07093 148 PMKGTI---DASLPNAEE--KLLNDEKEFAEHATIVDLLRNDLSMVAK--NVRVTRFRYIDKIKtnkgEILQTSSEISGT 220

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151  78 LRDDM-----DAFDGFLShawAVTVTGAPKLWAMRFIEGHEKSPRAWYGGAIGMvgFNG-DMNTGLTLRTIRIKDGIAEV 151
Cdd:PRK07093 221 LPENWqenigDILAKLLP---AGSITGAPKEKTVEIIEQAEGYERGFYTGVFGY--FDGeSLDSAVMIRFIEQENDGLYF 295

                        170
                 ....*....|....*
gi 297500151 152 RAGATLLNDSNPQEE 166
Cdd:PRK07093 296 KSGGGITIDSDLKDE 310
PRK15016 PRK15016
isochorismate synthase EntC; Provisional
 2-170 2.34e-07

isochorismate synthase EntC; Provisional


Pssm-ID: 184977 [Multi-domain]  Cd Length: 391  Bit Score: 49.10  E-value: 2.34e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151   2 PISGTIKRGDDPIADSEQILKLLNSKKDESELTMCS----DVDRNDKSRVCEPGSVKVIgrrqieMYSRLIHTVDHIEGR 77
Cdd:PRK15016 211 PLAGSARRQPDEVLDREAGNRLLASEKDRHEHELVTqamkEVLRERSSELHVPSSPQLI------TTPTLWHLATPFEGK 284

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151  78 LRDDMDAFD-GFLSHAwAVTVTGAPKLWAMRFIEGHEKSPRAWYGGAIGMVGFNGDMNTGLTLRTIRIKDGIAEVRAGAT 156
Cdd:PRK15016 285 ANAQENALTlACLLHP-TPALSGFPHQAAKQVIAELEPFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRENQVRLFAGAG 363

                        170
                 ....*....|....
gi 297500151 157 LLNDSNPQEEEAET 170
Cdd:PRK15016 364 IVPASSPLGEWRET 377
PRK15012 PRK15012
menaquinone-specific isochorismate synthase; Provisional
 97-169 4.35e-06

menaquinone-specific isochorismate synthase; Provisional


Pssm-ID: 184974 [Multi-domain]  Cd Length: 431  Bit Score: 45.60  E-value: 4.35e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 297500151  97 VTGAPKLWAMRFIEGHEKSPRAWYGGAIGMVGFNgDMNTGLTLRTIRIKDGIAEVRAGATLLNDSNPQEEEAE 169
Cdd:PRK15012 345 VAGLPRDLARQFIARHEPFTREWYAGSAGYLSLQ-QSEFCVSLRSAKVSGNVVRLYAGAGIVRGSDPEQEWQE 416
PRK06923 PRK06923
isochorismate synthase DhbC; Validated
 2-170 2.92e-05

isochorismate synthase DhbC; Validated


Pssm-ID: 235886 [Multi-domain]  Cd Length: 399  Bit Score: 43.18  E-value: 2.92e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151   2 PISGTIKRGDDPIADSEQILKLLNSKKDESELTMCSDVDRNDKSRVCepgsvkvigrRQIEMYSR--LIHT------VDH 73
Cdd:PRK06923 211 PLAGSRPRSDDPVEDKRRAEELLSSPKDLHEHAVVVEAVAAALRPYC----------HTLHVPEKpsVIHTeamwhlSTE 280

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297500151  74 IEGRLRD-DMDAFDgfLSHAWAVT--VTGAPKLWAMRFIEGHEKSPRAWYGGAIGMVGFNGDMNTGLTLRTIRIKDGIAE 150
Cdd:PRK06923 281 VKGELKDpNTSSLE--LAIALHPTpaVCGTPTEEAREAIQQIEPFDREFFTGMLGWSDLNGDGEWIVTIRCAEVEENTLR 358

                        170       180
                 ....*....|....*....|
gi 297500151 151 VRAGATLLNDSNPQEEEAET 170
Cdd:PRK06923 359 LYAGAGVVAESKPEDELAET 378
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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