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Conserved domains on  [gi|409194583|gb|AFV31602|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Agelaius tricolor]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475904)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 7.25e-162

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 455.82  E-value: 7.25e-162
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583   1 MNPQASLIFATSLLLGTIITISSNHWIMAWTGLEINTLAILPLISKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWH 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583  81 TGQWDITQLTHPMSCLILTSAIAMKLGLVPFHFWFPEVLQGSTLTTGLLLSTAMKLPPITLLYMTSPSLNPTLLTTLAIL 160
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583 161 SAALGGWMGLNQTQIRKILAFSSISHLGWMAIIIIYNPKLTLLNFYLYAMMTATVFLTLNTIKVLKLSTLMTAWTKIPSL 240
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583 241 NAMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQEMAPAATLISLLSLLSLFFYLRLAYCTTITLPPHTTNHMKQWRTNKP 320
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                        330       340
                 ....*....|....*....|....*.
gi 409194583 321 TNITIAILTTMSVMLLPISPMILTIV 346
Cdd:MTH00112 321 KNTLTATLTTLSTLLLPLSPMILTII 346
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 7.25e-162

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 455.82  E-value: 7.25e-162
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583   1 MNPQASLIFATSLLLGTIITISSNHWIMAWTGLEINTLAILPLISKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWH 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583  81 TGQWDITQLTHPMSCLILTSAIAMKLGLVPFHFWFPEVLQGSTLTTGLLLSTAMKLPPITLLYMTSPSLNPTLLTTLAIL 160
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583 161 SAALGGWMGLNQTQIRKILAFSSISHLGWMAIIIIYNPKLTLLNFYLYAMMTATVFLTLNTIKVLKLSTLMTAWTKIPSL 240
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583 241 NAMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQEMAPAATLISLLSLLSLFFYLRLAYCTTITLPPHTTNHMKQWRTNKP 320
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                        330       340
                 ....*....|....*....|....*.
gi 409194583 321 TNITIAILTTMSVMLLPISPMILTIV 346
Cdd:MTH00112 321 KNTLTATLTTLSTLLLPLSPMILTII 346
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-268 1.30e-21

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 93.15  E-value: 1.30e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583   23 SNHWIMAWTGLEINTLAILPLI-SKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWHTGQWDITQL-----------T 90
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELskaltgglnssG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583   91 HPMSCLILTSAIAMKLGLVPFHFWFPEVLQGSTLTTGLLLSTAMKLPPITLLYMTSPSLNPT------LLTTLAILSAAL 164
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAATLVKAGGYGLIRRSLLYLPSspfiqqILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583  165 GGWMGLNQTQIRKILAFSSISHLGWMAIII----IYNPKLTLLNFYLYAMMTATVFL-TLNTIKVLKLSTLMTA----WT 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLcAGSVIYRRVHTRNIRDygglAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 409194583  236 KIPSLNAMLLLTLLSLAGLPPLTGFLPKWLIIQ 268
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 7-298 1.77e-18

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 85.94  E-value: 1.77e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583   7 LIFATsllLGTIITISSNHWIMAWTGLEINTLAILPLIS-KSHHPRAIEAATKYFLTQAAASALVLF-SSMTNAWhTGQW 84
Cdd:COG1007  108 LLFAT---LGMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgISLLYGA-TGSL 183

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583  85 DITQLTHPMS------------CLILTSAIAMKLGLVPFHFWFPEVLQGSTLTTGLLLSTAMKL----PPITLLYMTSPS 148
Cdd:COG1007  184 NLAGIAAALAagganspllllgLVLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIaafaALLRLLVEAFPG 263

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583 149 LNP---TLLTTLAILSAALGGWMGLNQTQIRKILAFSSISHLGWMAIIIIYNPKLTL--LNFYL--YAMMTATVFLTLNT 221
Cdd:COG1007  264 LAAdwqLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLGVsaALFYLlaYLFMNLGAFAVILL 343

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583 222 IK-----VLKLSTLMTAWTKIPSLNAMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQEMAPAATLISLLSLLSLFFYLRL 296
Cdd:COG1007  344 LSrkggeAEEIEDLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRV 423


                 ..
gi 409194583 297 AY 298
Cdd:COG1007  424 VK 425
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 14-297 6.84e-17

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 81.15  E-value: 6.84e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583   14 LLGTIITISSNHWIMAWTGLEINTLAILPLIS-KSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWHTGQWDITQLTHP 92
Cdd:TIGR01770 112 LLGIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLLF 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583   93 MSCLILT------------SAIAMKLGLVPFHFWFPEVLQGSTLTTGLLLSTAMKLP---PITLLYMTSPS----LNPTL 153
Cdd:TIGR01770 192 LSNGMLNisllllgivlilVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAifaVFLRLFLYILFgfseAWQIF 271

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583  154 LTTLAILSAALGGWMGLNQTQIRKILAFSSISHLGWMAIIIIYNPKLTLLN--FYL--YAMMTATVFLTLNTIKVLK--- 226
Cdd:TIGR01770 272 LAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAvlFYIfiYALMSLGAFGVLSLLRSYKdew 351

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 409194583  227 ---LSTLMTAWTKIPSLNAMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQEMAPAATLISLLSLLSLFFYLRLA 297
Cdd:TIGR01770 352 ieyISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVV 425
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 7.25e-162

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 455.82  E-value: 7.25e-162
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583   1 MNPQASLIFATSLLLGTIITISSNHWIMAWTGLEINTLAILPLISKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWH 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583  81 TGQWDITQLTHPMSCLILTSAIAMKLGLVPFHFWFPEVLQGSTLTTGLLLSTAMKLPPITLLYMTSPSLNPTLLTTLAIL 160
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583 161 SAALGGWMGLNQTQIRKILAFSSISHLGWMAIIIIYNPKLTLLNFYLYAMMTATVFLTLNTIKVLKLSTLMTAWTKIPSL 240
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583 241 NAMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQEMAPAATLISLLSLLSLFFYLRLAYCTTITLPPHTTNHMKQWRTNKP 320
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                        330       340
                 ....*....|....*....|....*.
gi 409194583 321 TNITIAILTTMSVMLLPISPMILTIV 346
Cdd:MTH00112 321 KNTLTATLTTLSTLLLPLSPMILTII 346
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-346 1.34e-129

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 374.14  E-value: 1.34e-129
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583   1 MNPQASLIFATSLLLGTIITISSNHWIMAWTGLEINTLAILPLISKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWH 80
Cdd:MTH00135   1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583  81 TGQWDITQLTHPMSCLILTSAIAMKLGLVPFHFWFPEVLQGSTLTTGLLLSTAMKLPPITLLYMTSPSlNPTLLTTLAIL 160
Cdd:MTH00135  81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPT-NPTLLITLGLT 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583 161 SAALGGWMGLNQTQIRKILAFSSISHLGWMAIIIIYNPKLTLLNFYLYAMMTATVFLTLNTIKVLKLSTLMTAWTKIPSL 240
Cdd:MTH00135 160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPAL 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583 241 NAMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQEMAPAATLISLLSLLSLFFYLRLAYCTTITLPPHTTNHMKQWRTNKP 320
Cdd:MTH00135 240 TALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPST 319

                        330       340
                 ....*....|....*....|....*..
gi 409194583 321 -TNITIAILTTMSVMLLPISPMILTIV 346
Cdd:MTH00135 320 qLTLPLAISTTATLMLLPLTPAILALL 346
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-345 8.05e-128

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 369.64  E-value: 8.05e-128
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583   1 MNPQASLIFATSLLLGTIITISSNHWIMAWTGLEINTLAILPLISKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWH 80
Cdd:MTH00070   1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583  81 TGQWDITQLTHPMSCLILTSAIAMKLGLVPFHFWFPEVLQGSTLTTGLLLSTAMKLPPITLLYMTSPSLNPTLLTTLAIL 160
Cdd:MTH00070  81 TGEWTIMNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583 161 SAALGGWMGLNQTQIRKILAFSSISHLGWMAIIIIYNPKLTLLNFYLYAMMTATVFLTLNTIKVLKLSTLMTAWTKIPSL 240
Cdd:MTH00070 161 STLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583 241 NAMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQEMAPAATLISLLSLLSLFFYLRLAYCTTITLPPHTTNHMKQWRTNKP 320
Cdd:MTH00070 241 TSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRFKNK 320

                        330       340
                 ....*....|....*....|....*
gi 409194583 321 TNITIAILTTMSVMLLPISPMILTI 345
Cdd:MTH00070 321 TNNLLSLTIILSLMLLPITPTILNL 345
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-345 4.17e-112

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 329.88  E-value: 4.17e-112
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583   1 MNPQASLIFATSLLLGTIITISSNHWIMAWTGLEINTLAILPLISKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWH 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583  81 TGQWDITQLTHPMSCLILTSAIAMKLGLVPFHFWFPEVLQGSTLTTGLLLSTAMKLPPITLLYMTSPSLNPTLLTTLAIL 160
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583 161 SAALGGWMGLNQTQIRKILAFSSISHLGWMAIIIIYNPKLTLLNFYLYAMMTATVFLTLNTIKVLKLSTLMTAWTKIPSL 240
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583 241 NAMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQEMAPAATLISLLSLLSLFFYLRLAYCTTITLPPhTTNHMK-QWR-TN 318
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFP-STNNMKmKWQfEN 319

                        330       340
                 ....*....|....*....|....*..
gi 409194583 319 KPTNITIAILTTMSVMLLPISPMILTI 345
Cdd:MTH00105 320 TKPMTLLPTLIILSTMLLPLTPMLSIL 346
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-345 1.68e-93

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 282.24  E-value: 1.68e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583   1 MNPQASLIFATSLLLGTIITISSNHWIMAWTGLEINTLAILPLISKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWH 80
Cdd:MTH00200   1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583  81 TGQWDITQLTHPMSCLILTSAIAMKLGLVPFHFWFPEVLQGSTLTTGLLLSTAMKLPPITLLYMTSPSLNPTLLTTLAIL 160
Cdd:MTH00200  81 SGQWGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583 161 SAALGGWMGLNQTQIRKILAFSSISHLGWMAIIIIYNPKLTLLNFYLYAMMTATVFLTLNTIKVLKLSTLMTAWTKIPSL 240
Cdd:MTH00200 161 SVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPIL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583 241 NAMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQEMAPAATLISLLSLLSLFFYLRLAYCTTITLPPHTTNHMKQWRTNKP 320
Cdd:MTH00200 241 SMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWRTKSN 320

                        330       340
                 ....*....|....*....|....*
gi 409194583 321 TNITIAILTTMSVMLLPISPMILTI 345
Cdd:MTH00200 321 SNLLVGLLLLLSILGLPLTPQLLFL 345
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 1-336 1.68e-74

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 233.67  E-value: 1.68e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583   1 MNPQASLIFATSLLLGTIITISSNHWIMAWTGLEINTLAILPLISKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWH 80
Cdd:MTH00041   1 MNRNVLIFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583  81 TGQWDITQLTHPMSCLILTSAIAMKLGLVPFHFWFPEVLQGSTLTTGLLLSTAMKLPPITLLYMTSPSLNPTLLTTLAIL 160
Cdd:MTH00041  81 SGSWSINGPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583 161 SAALGGWMGLNQTQIRKILAFSSISHLGWMAIIIIYNPKLTLLNFYLYAMMTATVFLTLNTIKVLKLSTLMTAWTKIPSL 240
Cdd:MTH00041 161 SVLVGGWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPIS 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583 241 NAMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQEMAPAATLISLLSLLSLFFYLRLAYCTTITLPPHTTNHMKQWRTNKP 320
Cdd:MTH00041 241 AFLFILSILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHSISLFSWRNSGN 320

                        330
                 ....*....|....*.
gi 409194583 321 TNITIAILTTMSVMLL 336
Cdd:MTH00041 321 ITVYGVILSILSSISI 336
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-345 1.93e-51

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 173.86  E-value: 1.93e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583   1 MNPQASLIFATSLLLGTIITISSNHWIMAWTGLEINTLAILPLISKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWh 80
Cdd:MTH00160   2 MMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML- 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583  81 tgqwdITQLTHPMSCLILTSAIAMKLGLVPFHFWFPEVLQGSTLTTGLLLSTAMKLPPITLLYMTspsLNPTLLTTLAIL 160
Cdd:MTH00160  81 -----NLMLFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYL---INNNFIIIIIIL 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583 161 SAALGGWMGLNQTQIRKILAFSSISHLGWMAIIIIYNPKLTLLNFYLYAMMTATVFLTLNTIKVLKLSTLMTAWTKIPSL 240
Cdd:MTH00160 153 SAIIGAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKI 232

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583 241 NAMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQEMAPAATLISLLSLLSLFFYLRLAYCTTITLPPHTTNHMKQwrTNKP 320
Cdd:MTH00160 233 KFLLFLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKK--KKNK 310

                        330       340
                 ....*....|....*....|....*
gi 409194583 321 TNITIAILTTMSVMLLPISPMILTI 345
Cdd:MTH00160 311 FSLILNFLSFISLFGLILSSLLFLL 335
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 6-340 4.25e-42

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 149.16  E-value: 4.25e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583   6 SLIFATSLLLGTIITISSNHWIMAWTGLEINTLAILPLISKSHHPRAIEAATKYFLTQAAASALVLFSSmtnawhTGQWD 85
Cdd:MTH00011   8 MFLFSSTMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGM------TMMWS 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583  86 ITQLTHPMSCLILTSAIAMKLGLVPFHFWFPEVLQGSTLTTGLLLSTAMKLPPITLLYMTSPSLNPTLLTTLAILSAALG 165
Cdd:MTH00011  82 FPSLLKNITALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAMSALAG 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583 166 GWMGLNQTQIRKILAFSSISHLGWMAIIIIYNPKLTLLNFYLYAMMTATVFLTLNTIKVLKLSTLMTAWTKIPSLNAMLL 245
Cdd:MTH00011 162 GLGGMNQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLF 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583 246 LTLLSLAGLPPLTGFLPKWLIIQELTKQEMAPAATLISLLSLLSLFFYLRLAYcTTITLPPHTTNhmkqwRTNKPTNITI 325
Cdd:MTH00011 242 IMLLSLGGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIF-NFMYLSPTFSS-----LKSAPYEPKT 315

                        330
                 ....*....|....*
gi 409194583 326 AILTTMSVMLLPISP 340
Cdd:MTH00011 316 KILISMCTLSLGLIP 330
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 5-302 1.66e-40

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 144.64  E-value: 1.66e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583   5 ASLIFATSLLLGTIITISSNHWIMAWTGLEINTLAILPLISKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWHTGQW 84
Cdd:MTH00144   5 SNLLFLFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSW 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583  85 DITqlthpmscLILTSAIAMKLGLVPFHFWFPEVLQGSTLTTGLLLSTAMKLPPITLLYMTSPSLNP-TLLTTLAILSAA 163
Cdd:MTH00144  85 FSM--------SLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWLaYLLCVISVLSAL 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583 164 LGGWMGLNQTQIRKILAFSSISHLGWMAIIIIYNPKLTLLNFYLYAMMTATVFLTLNTiKVLKLSTLMTAWTKIPSLNAM 243
Cdd:MTH00144 157 VGSIGGLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWS-GDSGSMKDLGSLKPSYKTGLS 235

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 409194583 244 LLLTLLSLAGLPPLTGFLPKWLIIQELTKQEMAPAATLISLLSLLSLFFYLRLAYCTTI 302
Cdd:MTH00144 236 IISLLLSLGGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFL 294
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 8-342 1.57e-35

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 131.72  E-value: 1.57e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583   8 IFATSLLLGTIITISSNHWIMAWTGLEINTLAILPLISKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWHTgqwdit 87
Cdd:MTH00197   2 LFLFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSLSFSNL------ 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583  88 qLTHPMSCLILTSAIAMKLGLVPFHFWFPEVLQGSTLTTGLLLSTAMKLPPITLLymTSPSLNPTLLTTLAILSAALGGW 167
Cdd:MTH00197  76 -YLSLLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLIL--AFNSSSFMGLLICSVLSSLIGGI 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583 168 MGLNQTQIRKILAFSSISHLGWMAIIIIYNPKLTLLNFYLYAMMTATVFLTLNTIKVLKLSTlMTAWTKIPSLNAMLLLT 247
Cdd:MTH00197 153 GGMNQSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQ-QYSNPESMSSNLVFLGL 231

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583 248 LLSLAG-LPPLTGFLPKWLIIQELTKQEMAPAATLISLLSLLSLFFYLRLAYCTTItlppHTTNHMKQWRTNKPTNITIA 326
Cdd:MTH00197 232 SFLSLGgLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKSLI----LSNWMINFLMKINLLYSGLF 307

                        330
                 ....*....|....*.
gi 409194583 327 ILTTMSVMLLPISPMI 342
Cdd:MTH00197 308 ILLMMMLPLLMIFTMI 323
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-268 1.30e-21

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 93.15  E-value: 1.30e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583   23 SNHWIMAWTGLEINTLAILPLI-SKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWHTGQWDITQL-----------T 90
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELskaltgglnssG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583   91 HPMSCLILTSAIAMKLGLVPFHFWFPEVLQGSTLTTGLLLSTAMKLPPITLLYMTSPSLNPT------LLTTLAILSAAL 164
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAATLVKAGGYGLIRRSLLYLPSspfiqqILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583  165 GGWMGLNQTQIRKILAFSSISHLGWMAIII----IYNPKLTLLNFYLYAMMTATVFL-TLNTIKVLKLSTLMTA----WT 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLcAGSVIYRRVHTRNIRDygglAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 409194583  236 KIPSLNAMLLLTLLSLAGLPPLTGFLPKWLIIQ 268
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 13-267 1.65e-19

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 88.16  E-value: 1.65e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583  13 LLLGTIITISSNHWIMAWTGLEINTLAILPLI-SKSHHPRAIEAATKYFLTQAAASALVLFS-------------SMTNA 78
Cdd:MTH00196   2 VALGILCLISSSNWLSVYLAIELQTLSLFILIaQNRGSGYSAEAGLKYFVLGALSSGLFLFGcallcgttgglhlSYINL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583  79 WHTGQWDITQLTHPMSCLILTSAIAMKLGLVPFHFWFPEVLQGSTLTTGLLLSTAMKLPPITLLYMTSPSLNptLLTTLA 158
Cdd:MTH00196  82 VLNSGQSFSSVSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNVN--ILLIGG 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583 159 ILSAALGGWMGLNQTQIRKILAFSSISHLGWMAIII----IYNPKLTLLNFYLYAMMTATVFLTLNTIKVLK--LSTLMT 232
Cdd:MTH00196 160 LFSLFVGAIGALNQTKIKRLLAYSGIGHMGFVLWGIeigsFESIQASLVYLFIYIIMSICVFSIILALNVYKnlIIEFSG 239

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 409194583 233 AWTKIPSLNAMLLLTLLSLAGLPPLTGFLPKWLII 267
Cdd:MTH00196 240 LSRRLPILAITLALTFLSIAGIPPLVGFLGKWLIL 274
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 7-298 1.77e-18

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 85.94  E-value: 1.77e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583   7 LIFATsllLGTIITISSNHWIMAWTGLEINTLAILPLIS-KSHHPRAIEAATKYFLTQAAASALVLF-SSMTNAWhTGQW 84
Cdd:COG1007  108 LLFAT---LGMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgISLLYGA-TGSL 183

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583  85 DITQLTHPMS------------CLILTSAIAMKLGLVPFHFWFPEVLQGSTLTTGLLLSTAMKL----PPITLLYMTSPS 148
Cdd:COG1007  184 NLAGIAAALAagganspllllgLVLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIaafaALLRLLVEAFPG 263

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583 149 LNP---TLLTTLAILSAALGGWMGLNQTQIRKILAFSSISHLGWMAIIIIYNPKLTL--LNFYL--YAMMTATVFLTLNT 221
Cdd:COG1007  264 LAAdwqLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLGVsaALFYLlaYLFMNLGAFAVILL 343

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583 222 IK-----VLKLSTLMTAWTKIPSLNAMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQEMAPAATLISLLSLLSLFFYLRL 296
Cdd:COG1007  344 LSrkggeAEEIEDLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRV 423


                 ..
gi 409194583 297 AY 298
Cdd:COG1007  424 VK 425
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
14-296 3.19e-18

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 85.26  E-value: 3.19e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583  14 LLGTIITISSNHWIMAWTGLEINTLAILPLIS-KSHHPRAIEAATKYFLTQAAASALVL--------------FSSMTNA 78
Cdd:PRK05777 113 LLGMMVMVSANDLLTLFLGLELLSLPLYALAAlRRDRRRSLEAAIKYFVLGALASGFLLygmsllygatgslsFAGIAKA 192

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583  79 WHTGQWDITQLThpMSCLILTSAIAMKLGLVPFHFWFPEVLQGSTLTTGLLLSTAMKL----PPITLLYMTSPSLNPT-- 152
Cdd:PRK05777 193 LADGSGNSLLLL--FGLVFLLVGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIaafaVLLRLLVVAFGGLSEDwq 270

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583 153 -LLTTLAILSAALGGWMGLNQTQIRKILAFSSISHLGWMAIIIIYNPKLTL--LNFYL--YAMMTATVFLTLNTIK---- 223
Cdd:PRK05777 271 qVLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLAAGTAEGYsaVLFYLlaYLFMTLGAFGVISLLRrkgg 350

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 409194583 224 -VLKLSTL-MTAWTKiPSLNAMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQEMAPAATLISLLSLLSLFFYLRL 296
Cdd:PRK05777 351 eAESISDFaGLSKRS-PLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFYYLRV 424
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 14-297 6.84e-17

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 81.15  E-value: 6.84e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583   14 LLGTIITISSNHWIMAWTGLEINTLAILPLIS-KSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWHTGQWDITQLTHP 92
Cdd:TIGR01770 112 LLGIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLLF 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583   93 MSCLILT------------SAIAMKLGLVPFHFWFPEVLQGSTLTTGLLLSTAMKLP---PITLLYMTSPS----LNPTL 153
Cdd:TIGR01770 192 LSNGMLNisllllgivlilVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAifaVFLRLFLYILFgfseAWQIF 271

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583  154 LTTLAILSAALGGWMGLNQTQIRKILAFSSISHLGWMAIIIIYNPKLTLLN--FYL--YAMMTATVFLTLNTIKVLK--- 226
Cdd:TIGR01770 272 LAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAvlFYIfiYALMSLGAFGVLSLLRSYKdew 351

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 409194583  227 ---LSTLMTAWTKIPSLNAMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQEMAPAATLISLLSLLSLFFYLRLA 297
Cdd:TIGR01770 352 ieyISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVV 425
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 13-267 6.02e-16

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 78.52  E-value: 6.02e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583  13 LLLGTIITISSNHWIMAWTGLEINTLAILPLIS-KSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWHTGQWDI----T 87
Cdd:MTH00199 106 VALGSLLLVSSINWLSIYLAIELQTLTLFILVAlKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGETSIqginS 185

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583  88 QLTHPMSCLILTSAIAMKLGLVPFHFWFPEVLQGSTLTTGLLLSTAMKLPPITLLYMTSPSLNPTLLTtlAILSAALGGW 167
Cdd:MTH00199 186 ILTGDVGKILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNVVLIC--AVLSIIYGAI 263

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583 168 MGLNQTQIRKILAFSSISHLGW----MAIIIIYNPKLTLLNFYLYAMMTATVFLTLNTIKVLK--LSTLMTAWTKIPSLN 241
Cdd:MTH00199 264 GALNQTKIKRLLAYSGIGHMGFilfgVAIGSFESIQASLIYMIIYVIMSICSFSIILSLKLTKglIVEVSGLSRKNPVIA 343

                        250       260
                 ....*....|....*....|....*.
gi 409194583 242 AMLLLTLLSLAGLPPLTGFLPKWLII 267
Cdd:MTH00199 344 LTLALTFLSIAGIPPLAGFLSKWLIL 369
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 15-267 5.52e-12

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 66.81  E-value: 5.52e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583  15 LGTIITISSNHWIMAWTGLEINTLAILPLISKSHHPRAI---------EAATKYFLTQAAASALVLFSSMTNAWHTGQ-- 83
Cdd:MTH00198 199 LGGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFGCALYFGFTGNeg 278

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583  84 ------------WDITQLTHPMSCLILTSAIAMKLGLVPFHFWFPEVLQGSTLTTGLLLSTAMKLPPITLLymTSPSLNP 151
Cdd:MTH00198 279 mlgtilsatletTNIELRQGSLGYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILL--TSLVITS 356

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583 152 TLLTTLAILSAALGGWMGLNQTQIRKILAFSSISHLGWMAIIIIYNPKLTLLNFYLYAMM-------TATVFLTL----- 219
Cdd:MTH00198 357 KLLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFILIGVSAGTYESLQASWTYAVTylvsalaSFTVICTLeefgt 436

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 409194583 220 -------------NTIKVLKLSTLMTAWTKIPSLNAMLLLTLLSLAGLPPLTGFLPKWLII 267
Cdd:MTH00198 437 rtptsrqrdgsfgNYNLVRRLVDLTILSRGQPYIAFSLAIVFLSLAGIPPLLGFLGKWFIL 497
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 13-279 7.52e-12

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 65.94  E-value: 7.52e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583  13 LLLGTIITISSNHWIMAWTGLEINTLAILPLISKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWHTGQWDITQLTHP 92
Cdd:COG0651  116 LLAGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNMADLAAR 195

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583  93 MS----------CLILTSAIAMKLGLVPFHFWFPEvlqgstlttglllstAMKLPP----------------------IT 140
Cdd:COG0651  196 LAeldpglllaaFALLLVGFGIKAALFPLHFWLPD---------------AYPAAPspvsallsglltkvgvyailrvLT 260

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583 141 LLYMTSPSLNP-TLLTTLAILSAALGGWMGLNQTQIRKILAFSSISHLGWMAIIIIYNPKLTLLNFYLY----AMMTATV 215
Cdd:COG0651  261 LLFGADPALFLgTLLLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHllnhALAKALL 340

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 409194583 216 FLTLNTIKVL----KLSTLMTAWTKIPSLNAMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQEMAPAA 279
Cdd:COG0651  341 FLAAGAIERAtgtrDLDKLGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLA 408
NADH_dehy_S2_C pfam06444
NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region ...
 291-340 3.65e-09

NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region specific to the eukaryotic NADH dehydrogenase subunit 2 protein and is found in conjunction with pfam00361.


Pssm-ID: 461914 [Multi-domain]  Cd Length: 51  Bit Score: 51.87  E-value: 3.65e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 409194583  291 FFYLRLAYCTTITLPPHTTNHMKQWRTNKPTNIT-IAILTTMSVMLLPISP 340
Cdd:pfam06444   1 FFYLRLSYSTTLTLFPNTNNSKMKWRFNSTKNTLlLPTLTTLSILLLPLTP 51
ndhB CHL00049
NADH dehydrogenase subunit 2
 1-208 3.98e-09

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 57.71  E-value: 3.98e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583   1 MNPQASLIFATSLLLGTIITISSNHWIMAWTGLEINTLAILPLISKSHHP-RAIEAATKYFLTQAAASALVL--FSSM-- 75
Cdd:CHL00049 108 MAITEFLLFVLTATLGGMFLCGANDLITIFVALECLSLCSYLLSGYTKKDvRSNEATMKYLLMGGASSSILVygFSWLyg 187

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583  76 TNAWHTGQWDI------TQLTHPMSCLI----LTSAIAMKLGLVPFHFWFPEVLQGSTLTTGLLLSTAMKLPPITL---- 141
Cdd:CHL00049 188 LSGGEIELQEIvnglinTQMYNSPGISIalifITVGIGFKLSLAPFHQWTPDVYEGSPTPVVAFLSVTSKVAASALatri 267

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 409194583 142 LYMTSPSLNP---TLLTTLAILSAALGGWMGLNQTQIRKILAFSSISHLGWMAIIII-------YNPKLTLLNFYLY 208
Cdd:CHL00049 268 FDIPFYFSSNewhLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIvgdsndgYASMITYMLFYIF 344
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
50-192 3.42e-08

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 54.67  E-value: 3.42e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583  50 PRAIEAATKYFLTQAAASALVLF-SSMTNAWHTGQwdiTQLTHPMSCLI-------------LTSAIAMKLGLVPFHFWF 115
Cdd:PRK02504 157 PRSNEAALKYLLIGAASSAIFLYgSSLLYGLSGGS---TQLSAIALALItspslglalalvfVIAGIAFKISAVPFHQWT 233

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583 116 PEVLQGSTLTTGLLLSTAMKLP----PITLLYMTSPSLNP---TLLTTLAILSAALGGWMGLNQTQIRKILAFSSISHLG 188
Cdd:PRK02504 234 PDVYEGSPTPVVAFLSVGSKAAgfalAIRLLVTAFPSFDEqwkLLFTALAILSMVLGNVVALAQTSMKRMLAYSSIGQAG 313


                 ....
gi 409194583 189 WMAI 192
Cdd:PRK02504 314 FVMI 317
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-266 3.41e-07

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 51.64  E-value: 3.41e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583  33 LEINTLAILPLIS-KSHHPRAIEAATKYFLTQAAASALVLFS---------SMTNAWHTGQWDITQLTHPMSCL-ILTSA 101
Cdd:PRK08376 150 LEIMSIASYALVAfRNDTWEAIEAGIKYMFVGSLASSMVLLGiallygqygTLNMAYLAVKMSENPTVVAKIALaLFIAG 229

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583 102 IAMKLGLVPFHFWFPEVlQGSTLTTGLLLSTAMKLPPITLLY-----MTSPSLNPT----LLTTLAILSAALGGWMGLNQ 172
Cdd:PRK08376 230 LAMKSGAVPVHMWLPDA-YPAAPSSISAMLLVIKQAGLYALArvlfsIYGPAINLAtvgwVIIILGCLTMFVGVAMAVVQ 308

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583 173 TQIRKILAFSSISHLGWM------AIIIIYNPKLT----------LLNFYLYAMMTATVFLT-------LNTIKVLKLST 229
Cdd:PRK08376 309 KDVKRLLAYHSVSQIGYMllglgvGLAALGDPAMAsygeialaggIYHIVNHALYKALLFLTagaviyeTGTRNLNELGG 388

                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 409194583 230 LMTawtKIPSLNAMLLLTLLSLAGLPPLTGFLPKWLI 266
Cdd:PRK08376 389 LAR---TMPKTTIAFLIGAAAIVGLPPFNGFASKWLI 422
PRK12644 PRK12644
putative monovalent cation/H+ antiporter subunit A; Reviewed
 96-263 6.41e-07

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237154 [Multi-domain]  Cd Length: 965  Bit Score: 51.08  E-value: 6.41e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583  96 LILTSAIAmKLGLVPFHFWFPEVLQGSTLTTGLLLSTAMKLPPITLL------YMTSPSLNPTLLTtLAILSAALGGWMG 169
Cdd:PRK12644 208 LILVGALS-KSAIVPFHFWLPGAMAAPTPVSAYLHAAAMVKAGIYLVarlapgFADVPVWRPTVLV-LGLATMLLGGWRA 285

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583 170 LNQTQIRKILAFSSISHLGWMAIIIIYNPK------LTLLnfYLYAMMTATVFLTLNTI-------KVLKLSTLmtaWTK 236
Cdd:PRK12644 286 LRQHDLKLILAYGTVSQLGFLTVLVGIGTRdaalagLAML--LAHALFKAALFLVVGIIdhstgtrDIRKLSGL---GRR 360

                        170       180
                 ....*....|....*....|....*..
gi 409194583 237 IPSLNAMLLLTLLSLAGLPPLTGFLPK 263
Cdd:PRK12644 361 QPVLAVVAALAAASMAGLPPLLGFVAK 387
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 49-192 3.68e-06

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 48.54  E-value: 3.68e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583  49 HPRAIEAATKYFLTQAAASALVLFSSMTNAWHTGQW--DITQLTH-----PMSCLILTS---AIAMKLGLVPFHFWFPE- 117
Cdd:COG1008  156 GERRIYAAIKFFLYTLAGSLLMLVAILALYFLAGALtfDIAELAAaplplTAQLLLFLAffiAFAVKVPMFPFHTWLPDa 235

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583 118 --------------VLqgstlttglllstaMKLP-------PITLLYMTSPSLNPTLLTtLAILSAALGGWMGLNQTQIR 176
Cdd:COG1008  236 hveaptagsvllagVL--------------LKMGgygllrfALPLFPEASAYFAPLLAA-LGVIGIIYGALVALAQTDLK 300

                        170
                 ....*....|....*.
gi 409194583 177 KILAFSSISHLGWMAI 192
Cdd:COG1008  301 RLIAYSSVSHMGFVLL 316
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 2-275 6.99e-06

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 47.68  E-value: 6.99e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583   2 NPQASLIFATSLLLGTIITISSNHWIMAWTGLEINTLAILPLISKSHHpRAIEAATKYFLTQAAASALVLFSSMTNAWHT 81
Cdd:PRK08668  96 NDAYFNMFALMSLAGVLGVFLANDLLTLYIFWEIMTFSSFMMVPMGKK-ESRKASLKYFVLSAIGAYAMLYAIFLIYAKT 174

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583  82 GQWDITQLTHPMS-----------CLILTSAIAMKLGLVPFHFWFPEV------------------LQGSTLTTGLLLST 132
Cdd:PRK08668 175 GTFDFADISQGLIndtstgfalivFLFLLAFGVAKAGIFPLHVWAPDAyseapqsfsavlsgqlskLGAYGFLLVLYVLP 254

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583 133 AMKLPPITLLYMTSPSLNpTLLTTLAILSAALGGWMGLNQTQIRKILAFSSISHLGWMAIIIIYNPKLT----LLNFYLY 208
Cdd:PRK08668 255 GTKLFSEFGTYRGVPLFN-YILAWLGNISIIVGTLMAILQEDIKKLIAYSSVANGGYILVGLGLGTSLGfaggLFHVFNH 333

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 409194583 209 AMMTATVFLTLNTI----KVLKLSTLMTAWTKIPSLNAMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQEM 275
Cdd:PRK08668 334 ALFKGLFFLIFAAViyrtGTTKISEMGGLIEKMPFTFAMYLVAIISLAGIPPMSGFASKWLIFEALISKGM 404
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 23-190 9.94e-06

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 47.07  E-value: 9.94e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583  23 SNHWIMAWTGLEINTLAILPLISKSHH-PRAIEAATKYFLTQAAASALVLFSSMTNAWHTGQWDITQLTH---------- 91
Cdd:COG1009  130 SDNLLLLFVFWELVGLCSYLLIGFWYEkPSARRAARKAFLVTRVGDLGLLLGILLLGAIAGTLNFSELLAaaptilsspl 209

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583  92 --PMSCLILTSAIAmKLGLVPFHFWFPEvlqgstlttglllstAMKLP-PI-TLL----------YM---TSP--SLNPT 152
Cdd:COG1009  210 ltLILLLLLLGAFG-KSAQFPLHFWLPD---------------AMEGPtPVsALLhaatmvkagvYLlarLSPlfALSPV 273

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 409194583 153 LLTTLAILSAA---LGGWMGLNQTQIRKILAFSSISHLGWM 190
Cdd:COG1009  274 WLTVVAIIGAItalFAALIALAQTDIKRVLAYSTVSQLGYM 314
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 50-194 1.21e-05

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 46.86  E-value: 1.21e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583   50 PRAIEAATKYFLTQAAASALVLFSSMTNAW-HTGQWDITQL-THPMSC-------LILTSAIAMKLGLVPFHFWFPEV-L 119
Cdd:TIGR01972 152 PNRIYAAMKFFLYTLAGSLLMLLAILGLYFlGGGTFDLLELlNLPLPFgvqtwlfLAFFIAFAVKVPLFPLHTWLPDAhV 231

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583  120 QGSTLTTGLLLSTAMKLPP-------ITLLYMTSPSLNPtLLTTLAILSAALGGWMGLNQTQIRKILAFSSISHLGWMAI 192
Cdd:TIGR01972 232 EAPTAGSVILAGVLLKMGTygflrfnLPLFPDASLYFAP-VLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVLL 310


                  ..
gi 409194583  193 II 194
Cdd:TIGR01972 311 GI 312
PRK12650 PRK12650
DUF4040 family protein;
80-194 1.16e-04

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 43.88  E-value: 1.16e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583  80 HTGQW-DITQLTHPMSCLILTSAIAmKLGLVPFHFWFPEVLQGSTLTTGLLLSTAMKLPPITLLYMTSPSL--NPT---L 153
Cdd:PRK12650 196 HSDVWaEKPGLTTVVAVLIAVAAFT-KSAQFPFHFWLPEAMAAITPVSAFLHAAAVVKAGIYLLLRFSPVFhdVAVwnwL 274

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 409194583 154 LTTLAILSAALGGWMGLNQTQIRKILAFSSISHLGWMAIII 194
Cdd:PRK12650 275 LIIVGMITALMGAVFAVQKTDLKKLTAYSTVSQLGWIVATI 315
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 9-194 1.98e-03

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 39.74  E-value: 1.98e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583   9 FATSLLLGTI-ITISSNHWIMAWTGLEINTLAILPLISKSHHPRAIEAATKYFLTQAAA------SALVLFSSMTNAWHT 81
Cdd:PRK08676 106 LGFNLLLSVItFAFFSDNLALFWIFAELTTVFSAMLIAILSARENIDAALKYIFIASTAmifafiGLIFLFSLTRQALGT 185

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583  82 GQWDITQLTHP----------MSCLILTSAIAMKLGLVPFHFWFPEVLQGSTLTTGLLLSTAMKLPPITLLYMTSPSLNP 151
Cdd:PRK08676 186 GTLNWTELAAHasllspsvlgASFLFIFIGFLAKSGLVPFHTWLPAAYAKAPSVVSALLSGTVLNIGIYGILRLSALLRQ 265

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 409194583 152 T--------LLTTLAILSAALGGWMGLNQTQIRKILAFSSISHLGWMAIII 194
Cdd:PRK08676 266 SgaaeqfsnVLIGLGIFSIAVAAFSMLSQRNLKKLIAFSSIEHMGLMLLGI 316
ND5 MTH00032
NADH dehydrogenase subunit 5; Provisional
 92-271 2.24e-03

NADH dehydrogenase subunit 5; Provisional


Pssm-ID: 214407 [Multi-domain]  Cd Length: 669  Bit Score: 39.94  E-value: 2.24e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583  92 PMSCLILTSAI--AMKLGLvpfHFWFPEVLQGSTLTTGLLLSTAMKLPPITLLYMTSPSLNPTLLTTLAI-----LSAAL 164
Cdd:MTH00032 226 IIGILLLIGCIgkSAQLGL---HTWLPDAMEGPTPVSALIHAATMVTAGVFLMIRSFPLFEKAPLTLLIItifgaLTAFF 302

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583 165 GGWMGLNQTQIRKILAFSSISHLGWMAIIIIY--NPKLTLLNFYLYAMMTATVFLTLNTI---------KVLKLSTLMTA 233
Cdd:MTH00032 303 AATVGLVQNDLKKVIAYSTCSQLGYMVLIIGIegSHNVGLFHLVNHAFFKALLFLSAGSVihsttvdeqDMRKMGGLIHS 382

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 409194583 234 wtkIPSLNAMLLLTLLSLAGLPPLTGFLPKWLIIqELT 271
Cdd:MTH00032 383 ---IPFTYTMMLIGSFSIMGLPYLTGFYSKDLIL-ELT 416
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
55-190 2.85e-03

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 39.30  E-value: 2.85e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583  55 AATKYFLTQAAASALVLFSSMTNAWHTG--QWDITQL---THPMSCLILTSA-----IAMKLGLVPFHFWFPEV-LQGST 123
Cdd:PRK06473 158 AATKFLLYTAISGILILVSFLGLVWLSGasSFDYEPLrshTLPLSTQLLLLApilvgFGIKIPLVPFHTWLPDAhVEAST 237

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 409194583 124 LTTGLLLSTAMKLPPITLL------YMTSPSLNPTLLTTLAILSAALGGWMGLNQTQIRKILAFSSISHLGWM 190
Cdd:PRK06473 238 PVSVLLAGVLLKLGTYGLLrfgvglFPEAWVYLAPWLATWAVVSVLYGASCAIAQKDMKKMVAYSSIGHMGYI 310
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 50-194 3.84e-03

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 39.03  E-value: 3.84e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583  50 PRAIEAATKYFLTQAAASALVLFSSMTNAWH----TGQWDITQL-THPMSC-------LILTSAIAMKLGLVPFHFWFPE 117
Cdd:PRK05846 157 KNRIYAATKFFLYTLLGSLLMLVAIIYLVVVyynaTGTFDIADLlNLPLPPgvqywlfLAFFIAFAVKMPMFPLHTWLPD 236

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583 118 V-LQGSTLTTGLLLSTAMKLPPITLLYMTSPsLNP-------TLLTTLAILSAALGGWMGLNQTQIRKILAFSSISHLGW 189
Cdd:PRK05846 237 AhVQAPTAGSVLLAGILLKMGAYGLLRFSLP-LFPdashefaPIIITLGVIAIIYGALVALAQTDIKKLIAYSSISHMGF 315


                 ....*
gi 409194583 190 MAIII 194
Cdd:PRK05846 316 VTLGI 320
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 8-192 4.68e-03

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 38.76  E-value: 4.68e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583   8 IFATSLLLgtiiTISSNHWIMAWTGLEINTLAILPLISKSHHPRAIEAATKYFLTQAAASALVLFSSM---TNAWhtgqw 84
Cdd:PRK06458 116 LFLFTMLL----ALTSNNLGLMWVAIEATTLSSALLVGIYRTRASLEAAWKYIIICSVGVAFALFGTIlvyANAA----- 186

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583  85 diTQLTHPMSCLILTSAIAM----------------------KLGLVPFHFWFPE-----------VLQGSTLTTGLLLS 131
Cdd:PRK06458 187 --TVMGDGEMAILWTELLKHaslldptlmklafvflligfgtKVGLFPMHAWLPDahseapspvsaLLSGVLLNVALYAV 264

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 409194583 132 TAMKlppITLLYMTSPSLNPTLLTTLAILSAALGGWMGLNQTQIRKILAFSSISHLGWMAI 192
Cdd:PRK06458 265 LRYY---ILIDAAIGSDFPGRLLLIFGLLSVLVAAFFLLRQRDIKRLFAYSSIEHMGLIAF 322
PRK12647 PRK12647
putative monovalent cation/H+ antiporter subunit A; Reviewed
 109-266 5.96e-03

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237156 [Multi-domain]  Cd Length: 761  Bit Score: 38.36  E-value: 5.96e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583 109 VPFHFWFPEVLQGSTLTTGLLLSTAMKLPPITLLYMTSPSLNPTLL--TTLAILSAA---LGGWMGLNQTQIRKILAFSS 183
Cdd:PRK12647 212 FPFHFWLPNAMEAPTPVSAYLHSATMVKAGIYLLARLNPVLGGTPLwqTILPLFGGLtmlTGALLAVRQTDLKLILAYST 291

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583 184 ISHLGWMAIIIIYNPKLTLLNFYLY----AMMTATVFLTLNTIK-------VLKLSTLmtaWTKIPSLNAMLLLTLLSLA 252
Cdd:PRK12647 292 VSALGTLVMLLGLGSELAIKAAVLFlvahSLYKGALFMVAGIIDhetgtrdITKLGGL---RRAMPITAAAALLAALSMA 368

                        170
                 ....*....|....
gi 409194583 253 GLPPLTGFLPKWLI 266
Cdd:PRK12647 369 GLPPLFGFLAKELI 382
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-298 6.02e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 38.32  E-value: 6.02e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583  33 LEINTLAILPLISKSHHPRAIEAATKYFLTQAAASALVLFS-SMTNAwHTGQWDITQLTH--PMSCLILT------SAIA 103
Cdd:PRK08375 135 LEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGvGLLYG-VTGTLNMADLAGalAENPTVVTafgfvlLALA 213

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583 104 MKLGLVPFHFWFPEvlqgstlttglllstAMKLPP--ITLL------------------------YMTSPSLNpTLLTTL 157
Cdd:PRK08375 214 LKAAVFPLHTWLPR---------------AYPAAPpvVTALlsglvtkvavyaliriyftvfggdFRFALGLG-WLLAVL 277

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583 158 AILSAALGGWMGLNQTQIRKILAFSSISHLGWMAIIIIYNPKLTLLN--FYL--YAMMTATVFLTLNTIKVL----KLST 229
Cdd:PRK08375 278 ALLSMLVGSLAALGQDDVKRVLAYSTVSQMGYILLGLALLTPLALAAglLHLlhHALMKGALFLAAGAIEVTygtrRLSE 357

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 409194583 230 LMTAWTKIPSLNAMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQEMAPAATLISLLSLLSLFFYLRLAY 298
Cdd:PRK08375 358 LSGLGRRMPLTAAAFAVASLSLIGVPPTSGFVSKWYLVVGAVEAGQWLVLAVLLASSLLALLYFLRIWY 426
PRK06590 PRK06590
NADH:ubiquinone oxidoreductase subunit L; Reviewed
 148-190 7.77e-03

NADH:ubiquinone oxidoreductase subunit L; Reviewed


Pssm-ID: 235836 [Multi-domain]  Cd Length: 624  Bit Score: 38.22  E-value: 7.77e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 409194583 148 SLNPTLLTTLAILSAA---LGGWMGLNQTQIRKILAFSSISHLGWM 190
Cdd:PRK06590 275 ELSPEALLFVAIVGAVtalFAAFIGLVQTDIKRVLAYSTMSQLGYM 320
PRK12662 PRK12662
putative monovalent cation/H+ antiporter subunit D; Reviewed
 142-267 8.07e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 183662 [Multi-domain]  Cd Length: 492  Bit Score: 37.79  E-value: 8.07e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409194583 142 LYMTSPSLNpTLLTTLAILSAALGGWMGLNQTQIRKILAFSSISHLGWMAIIIIYNPKLTLLNFYLY----AMMTATVFL 217
Cdd:PRK12662 271 FVFTTLPFN-NVFMILAALAIVFGSVLAILSKDIKRIFAYSSISHIGYIILAVSLNTYYGLAAAVAYivnhSIVKSALFM 349

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 409194583 218 TLNTIKV----LKLSTLMTAWTKIPSLNAMLLLTLLSLAGLPPLTGFLPKWLII 267
Cdd:PRK12662 350 VSGSISYhfgtTKLEDCLNLWKSMPKITLAFVLLSLSLIGMPPTSGFVAKWYIL 403
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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