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Conserved domains on  [gi|662035233|gb|AIE43312|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Xiphophorus birchmanni]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475913)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-347 1.96e-177

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 495.48  E-value: 1.96e-177
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233   1 MAPFVCSTLIISLGLGTTMTFASTHWYLAWMGIEINTLAIIPLMTQNHNPRTIEATTKYFFAQATASATLLFAAVSNAFL 80
Cdd:MTH00135   1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  81 TGGWDILQTNHPLTSTLITLALAMKIGLAPLHSWMPEVMQGVSLLTGLTLSTWQKLAPLCLIYQIQPNSPSVFTTLGLLS 160
Cdd:MTH00135  81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPTNPTLLITLGLTS 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233 161 VIVGGWGGLNQIQLRKILAYSSIAHLGWMIIILPFSSPLTLLTLFTYLMMTFSLFSSFMLIRTTHINSLSTSWAKIPALT 240
Cdd:MTH00135 161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALT 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233 241 ASVPLILLSLGGLPPLTGFLPKWLILQELTKQDLAPIATLAALSSLFSLYFYLRLSYTMTLTMSPNNPTGTLPWRLNPRH 320
Cdd:MTH00135 241 ALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPSTQ 320

                        330       340
                 ....*....|....*....|....*..
gi 662035233 321 NTLPLALTTTTTIFLLPATPAILALFT 347
Cdd:MTH00135 321 LTLPLAISTTATLMLLPLTPAILALLT 347
 
Name Accession Description Interval E-value
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-347 1.96e-177

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 495.48  E-value: 1.96e-177
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233   1 MAPFVCSTLIISLGLGTTMTFASTHWYLAWMGIEINTLAIIPLMTQNHNPRTIEATTKYFFAQATASATLLFAAVSNAFL 80
Cdd:MTH00135   1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  81 TGGWDILQTNHPLTSTLITLALAMKIGLAPLHSWMPEVMQGVSLLTGLTLSTWQKLAPLCLIYQIQPNSPSVFTTLGLLS 160
Cdd:MTH00135  81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPTNPTLLITLGLTS 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233 161 VIVGGWGGLNQIQLRKILAYSSIAHLGWMIIILPFSSPLTLLTLFTYLMMTFSLFSSFMLIRTTHINSLSTSWAKIPALT 240
Cdd:MTH00135 161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALT 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233 241 ASVPLILLSLGGLPPLTGFLPKWLILQELTKQDLAPIATLAALSSLFSLYFYLRLSYTMTLTMSPNNPTGTLPWRLNPRH 320
Cdd:MTH00135 241 ALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPSTQ 320

                        330       340
                 ....*....|....*....|....*..
gi 662035233 321 NTLPLALTTTTTIFLLPATPAILALFT 347
Cdd:MTH00135 321 LTLPLAISTTATLMLLPLTPAILALLT 347
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-267 7.33e-21

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 90.84  E-value: 7.33e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233   23 STHWYLAWMGIEINTLAIIPLMTQNH-NPRTIEATTKYFFAQATASATLLFA--AVSNAFLTGGWDILQTNHPLT----- 94
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGYWGkSPRSSEAGMKYFLLTLLGSSILLFGisLMYNYTGTLSFDELSKALTGGlnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233   95 ----STLITLALAMKIGLAPLHSWMPEVMQGVSLLTGLTL-STWQKLAPLCLIYQIQPNSPS------VFTTLGLLSVIV 163
Cdd:pfam00361  81 llllFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLaATLVKAGGYGLIRRSLLYLPSspfiqqILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  164 GGWGGLNQIQLRKILAYSSIAHLGWMIIILpFSSPLTLLTLFTYLMMTFSLFSS--FMLI--------RTTHINSLSTSW 233
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIAL-GAGTIYGIQAAIFHLLTHGLFSAglFLCAgsviyrrvHTRNIRDYGGLA 239

                         250       260       270
                  ....*....|....*....|....*....|....
gi 662035233  234 AKIPALTASVPLILLSLGGLPPLTGFLPKWLILQ 267
Cdd:pfam00361 240 KTMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 15-299 1.72e-16

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 80.16  E-value: 1.72e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  15 LGTTMTFASTHWYLAWMGIEINTLAIIPL-MTQNHNPRTIEATTKYFFAQATASATLLFAAVSNAFLTGGWDILQ----- 88
Cdd:COG1007  113 LGMMLMASANDLLTLFLGLELLSLSLYVLvAFRRDDRRSSEAALKYFLLGALSSGFLLYGISLLYGATGSLNLAGiaaal 192

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  89 TNHPLTSTLITLALAM-------KIGLAPLHSWMPEVMQGVSLLTGLTLSTWQKLAPLCLIYQI-----QPNSPSVFTTL 156
Cdd:COG1007  193 AAGGANSPLLLLGLVLvlaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLRLlveafPGLAADWQLLL 272

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233 157 GLLSV---IVGGWGGLNQIQLRKILAYSSIAHLGWMIIILPFSSPLTLLTLFTYLM----MTFSLFSSFMLIR-----TT 224
Cdd:COG1007  273 AVLAVlsmTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLGVSAALFYLLaylfMNLGAFAVILLLSrkggeAE 352

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233 225 HINSLSTSWAKIPALTAS----------VPlillslgglpPLTGFLPKWLILQELTKQDLAPIATLAALSSLFSLYFYLR 294
Cdd:COG1007  353 EIEDLAGLARRSPLLALAmtifllslagIP----------PTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLR 422


                 ....*
gi 662035233 295 LSYTM 299
Cdd:COG1007  423 VVKAM 427
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 23-299 1.57e-14

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 74.21  E-value: 1.57e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233   23 STHWYLAWMGIEINTLAIIPLMT-QNHNPRTIEATTKYFFAQATASATLLFAAVSNAFLTGGWDILQTNHPLTST----- 96
Cdd:TIGR01770 121 SNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLLFLSNGmlnis 200

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233   97 -------LITLALAMKIGLAPLHSWMPEVMQGVSLLTGLTLSTWQKLAPLCLIYQIQPNSPSVFTT--------LGLLSV 161
Cdd:TIGR01770 201 llllgivLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYILFGFSEawqiflaiIAFLSM 280

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  162 IVGGWGGLNQIQLRKILAYSSIAHLGWMIIILPFSS----PLTLLTLFTYLMMTFSLFSSFMLIRTT------HINSLST 231
Cdd:TIGR01770 281 LIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTlegiKAVLFYIFIYALMSLGAFGVLSLLRSYkdewieYISDFAG 360

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 662035233  232 SWAKIPALTASVPLILLSLGGLPPLTGFLPKWLILQELTKQDLAPIATLAALSSLFSLYFYLRLSYTM 299
Cdd:TIGR01770 361 LFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVVKVM 428
 
Name Accession Description Interval E-value
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-347 1.96e-177

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 495.48  E-value: 1.96e-177
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233   1 MAPFVCSTLIISLGLGTTMTFASTHWYLAWMGIEINTLAIIPLMTQNHNPRTIEATTKYFFAQATASATLLFAAVSNAFL 80
Cdd:MTH00135   1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  81 TGGWDILQTNHPLTSTLITLALAMKIGLAPLHSWMPEVMQGVSLLTGLTLSTWQKLAPLCLIYQIQPNSPSVFTTLGLLS 160
Cdd:MTH00135  81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPTNPTLLITLGLTS 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233 161 VIVGGWGGLNQIQLRKILAYSSIAHLGWMIIILPFSSPLTLLTLFTYLMMTFSLFSSFMLIRTTHINSLSTSWAKIPALT 240
Cdd:MTH00135 161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALT 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233 241 ASVPLILLSLGGLPPLTGFLPKWLILQELTKQDLAPIATLAALSSLFSLYFYLRLSYTMTLTMSPNNPTGTLPWRLNPRH 320
Cdd:MTH00135 241 ALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPSTQ 320

                        330       340
                 ....*....|....*....|....*..
gi 662035233 321 NTLPLALTTTTTIFLLPATPAILALFT 347
Cdd:MTH00135 321 LTLPLAISTTATLMLLPLTPAILALLT 347
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-346 2.05e-128

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 371.18  E-value: 2.05e-128
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233   1 MAPFVCSTLIISLGLGTTMTFASTHWYLAWMGIEINTLAIIPLMTQNHNPRTIEATTKYFFAQATASATLLFAAVSNAFL 80
Cdd:MTH00070   1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  81 TGGWDILQTNHPLTSTLITLALAMKIGLAPLHSWMPEVMQGVSLLTGLTLSTWQKLAPLCLIYQIQPN-SPSVFTTLGLL 159
Cdd:MTH00070  81 TGEWTIMNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLlNSNLLIIMGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233 160 SVIVGGWGGLNQIQLRKILAYSSIAHLGWMIIILPFSSPLTLLTLFTYLMMTFSLFSSFMLIRTTHINSLSTSWAKIPAL 239
Cdd:MTH00070 161 STLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233 240 TASVPLILLSLGGLPPLTGFLPKWLILQELTKQDLAPIATLAALSSLFSLYFYLRLSYTMTLTMSPNNPTGTLPWRLNPr 319
Cdd:MTH00070 241 TSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRFKN- 319

                        330       340
                 ....*....|....*....|....*..
gi 662035233 320 HNTLPLALTTTTTIFLLPATPAILALF 346
Cdd:MTH00070 320 KTNNLLSLTIILSLMLLPITPTILNLF 346
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 2.76e-115

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 337.95  E-value: 2.76e-115
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233   1 MAPFVCSTLIISLGLGTTMTFASTHWYLAWMGIEINTLAIIPLMTQNHNPRTIEATTKYFFAQATASATLLFAAVSNAFL 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  81 TGGWDILQTNHPLTSTLITLALAMKIGLAPLHSWMPEVMQGVSLLTGLTLSTWQKLAPLCLIYQIQPN-SPSVFTTLGLL 159
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSlNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233 160 SVIVGGWGGLNQIQLRKILAYSSIAHLGWMIIILPFSSPLTLLTLFTYLMMTFSLFSSFMLIRTTHINSLSTSWAKIPAL 239
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233 240 TASVPLILLSLGGLPPLTGFLPKWLILQELTKQDLAPIATLAALSSLFSLYFYLRLSYTMTLTMSPNNPTGTLPWRLNPR 319
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                        330       340
                 ....*....|....*....|....*..
gi 662035233 320 HNtLPLALTTTTTIFLLPATPAILALF 346
Cdd:MTH00112 321 KN-TLTATLTTLSTLLLPLSPMILTII 346
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-346 4.71e-111

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 327.19  E-value: 4.71e-111
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233   1 MAPFVCSTLIISLGLGTTMTFASTHWYLAWMGIEINTLAIIPLMTQNHNPRTIEATTKYFFAQATASATLLFAAVSNAFL 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  81 TGGWDILQTNHPLTSTLITLALAMKIGLAPLHSWMPEVMQGVSLLTGLTLSTWQKLAPLCLIYQIQPN-SPSVFTTLGLL 159
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSiNPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233 160 SVIVGGWGGLNQIQLRKILAYSSIAHLGWMIIILPFSSPLTLLTLFTYLMMTFSLFSSFMLIRTTHINSLSTSWAKIPAL 239
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233 240 TASVPLILLSLGGLPPLTGFLPKWLILQELTKQDLAPIATLAALSSLFSLYFYLRLSYTMTLTMSPNNPTGTLPWRLNPR 319
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                        330       340
                 ....*....|....*....|....*..
gi 662035233 320 HNTLPLALTTTTTIFLLPATPAILALF 346
Cdd:MTH00105 321 KPMTLLPTLIILSTMLLPLTPMLSILE 347
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-347 3.65e-97

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 291.87  E-value: 3.65e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233   1 MAPFVCSTLIISLGLGTTMTFASTHWYLAWMGIEINTLAIIPLMTQNHNPRTIEATTKYFFAQATASATLLFAAVSNAFL 80
Cdd:MTH00200   1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  81 TGGWDILQTNHPLTSTLITLALAMKIGLAPLHSWMPEVMQGVSLLTGLTLSTWQKLAPLCLIYQIQPNS-PSVFTTLGLL 159
Cdd:MTH00200  81 SGQWGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALnSNILLLLGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233 160 SVIVGGWGGLNQIQLRKILAYSSIAHLGWMIIILPFSSPLTLLTLFTYLMMTFSLFSSFMLIRTTHINSLSTSWAKIPAL 239
Cdd:MTH00200 161 SVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPIL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233 240 TASVPLILLSLGGLPPLTGFLPKWLILQELTKQDLAPIATLAALSSLFSLYFYLRLSYTMTLTMSPNNPTGTLPWRLNPR 319
Cdd:MTH00200 241 SMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWRTKSN 320

                        330       340
                 ....*....|....*....|....*...
gi 662035233 320 HNtLPLALTTTTTIFLLPATPAILALFT 347
Cdd:MTH00200 321 SN-LLVGLLLLLSILGLPLTPQLLFLFF 347
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 9-317 1.30e-80

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 249.46  E-value: 1.30e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233   9 LIISLGLGTTMTFASTHWYLAWMGIEINTLAIIPLMTQNHNPRTIEATTKYFFAQATASATLLFAAVSNAFLTGGWDILQ 88
Cdd:MTH00041   9 LITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWLSGSWSING 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  89 TNHPLTSTLITLALAMKIGLAPLHSWMPEVMQGVSLLTGLTLSTWQKLAPLCLIYQIQPNSPS-VFTTLGLLSVIVGGWG 167
Cdd:MTH00041  89 PLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSnILILCGILSVLVGGWG 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233 168 GLNQIQLRKILAYSSIAHLGWMIIILPFSSPLTLLTLFTYLMMTFSLFSSFMLIRTTHINSLSTSWAKIPALTASVPLIL 247
Cdd:MTH00041 169 GLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPISAFLFILSI 248

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233 248 LSLGGLPPLTGFLPKWLILQELTKQDLAPIATLAALSSLFSLYFYLRLSYTMTLTMSPNNPTGTLPWRLN 317
Cdd:MTH00041 249 LSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHSISLFSWRNS 318
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 10-307 1.78e-57

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 189.26  E-value: 1.78e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  10 IISLGLGTTMTFASTHWYLAWMGIEINTLAIIPLMTQNHNPRTIEATTKYFFAQATASATLLFAAVSNAFLtggwdiLQT 89
Cdd:MTH00160  11 LSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNMLN------LML 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  90 NHPLTSTLITLALAMKIGLAPLHSWMPEVMQGVSLLTGLTLSTWQKLAPLCLIYQIqpNSPSVFTTLGLLSVIVGGWGGL 169
Cdd:MTH00160  85 FNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYL--INNNFIIIIIILSAIIGAIGGL 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233 170 NQIQLRKILAYSSIAHLGWMIIILPFSSPLTLLTLFTYLMMTFSLFSSFMLIRTTHINSLSTSWAKIPALTASVPLILLS 249
Cdd:MTH00160 163 NQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLLFLNLLS 242

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 662035233 250 LGGLPPLTGFLPKWLILQELTKQDLAPIATLAALSSLFSLYFYLRLSYTMTLTMSPNN 307
Cdd:MTH00160 243 LGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKN 300
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 13-304 6.75e-48

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 164.29  E-value: 6.75e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  13 LGLGTTMTFASTHWYLAWMGIEINTLAIIPLMTQNHNPRTIEATTKYFFAQATASATLLFAAVSNAFLTGGWDIlqtnhp 92
Cdd:MTH00144  13 MVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSWFS------ 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  93 ltSTLITLALAMKIGLAPLHSWMPEVMQGVSLLTGLTLSTWQKLAPLCLIYQIQPNSPSVFT--TLGLLSVIVGGWGGLN 170
Cdd:MTH00144  87 --MSLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWLAYLlcVISVLSALVGSIGGLN 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233 171 QIQLRKILAYSSIAHLGWMIIILPFSSPLTLLTLFTYLMMTFSLFSSFMLIRTTHINSLSTSwAKIPALTASVPLILLSL 250
Cdd:MTH00144 165 QTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDLGSL-KPSYKTGLSIISLLLSL 243

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 662035233 251 GGLPPLTGFLPKWLILQELTKQDLAPIATLAALSSLFSLYFYLRLSYTMTLTMS 304
Cdd:MTH00144 244 GGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSS 297
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 12-304 1.45e-42

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 150.32  E-value: 1.45e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  12 SLGLGTTMTFASTHWYLAWMGIEINTLAIIPLMTQNHNPRTIEATTKYFFAQATASATLLFAAVSNAFLTGgwdilQTNH 91
Cdd:MTH00011  14 TMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTMMWSFPS-----LLKN 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  92 PlTSTLITLALAMKIGLAPLHSWMPEVMQGVSLLTGLTLSTWQKLAPLCLIYQIQPNSPSVF-TTLGLLSVIVGGWGGLN 170
Cdd:MTH00011  89 I-TALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMmTSMAAMSALAGGLGGMN 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233 171 QIQLRKILAYSSIAHLGWMIIILPFSSPLTLLTLFTYLMMTFSLFSSFMLIRTTHINSLSTSWAKIPALTASVPLILLSL 250
Cdd:MTH00011 168 QTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLFIMLLSL 247

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 662035233 251 GGLPPLTGFLPKWLILQELTKQDLAPIATLAALSSLFSLYFYLRLSYTMTLTMS 304
Cdd:MTH00011 248 GGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFNFMYLSP 301
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 11-298 3.67e-40

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 144.04  E-value: 3.67e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  11 ISLGLGTTMTFASTHWYLAWMGIEINTLAIIPLMTQNHNPRTIEATTKYFFAQATASATLLFaavsnafltGGWDILQTN 90
Cdd:MTH00197   5 FIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLM---------GGSLSFSNL 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  91 H--PLTSTLITLALAMKIGLAPLHSWMPEVMQGVSLLTGLTLSTWQKLAPLCLIYQIQpNSPSVFTTLGLLSVIVGGWGG 168
Cdd:MTH00197  76 YlsLLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFNS-SSFMGLLICSVLSSLIGGIGG 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233 169 LNQIQLRKILAYSSIAHLGWMIIILPFSSPLTLLTLFTYLMMTFSLFSSFMLIRTTHINSLSTSWAKIPALTASVPLILL 248
Cdd:MTH00197 155 MNQSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLSFL 234

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 662035233 249 SLGGLPPLTGFLPKWLILQELTKQDLAPIATLAALSSLFSLYFYLRLSYT 298
Cdd:MTH00197 235 SLGGLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYK 284
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 15-295 6.86e-23

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 97.79  E-value: 6.86e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  15 LGTTMTFASTHWYLAWMGIEINTLAIIPLMTQNHNP-RTIEATTKYFFAQATASATLLFAAVSNAFLTGGWDILQTN--- 90
Cdd:MTH00196   4 LGILCLISSSNWLSVYLAIELQTLSLFILIAQNRGSgYSAEAGLKYFVLGALSSGLFLFGCALLCGTTGGLHLSYINlvl 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  91 ----------HPLTSTLITLALAMKIGLAPLHSWMPEVMQGVSLLTGLTLSTWQKLAPLCLIYQIQPNSpSVFTTLGLLS 160
Cdd:MTH00196  84 nsgqsfssvsVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNV-NILLIGGLFS 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233 161 VIVGGWGGLNQIQLRKILAYSSIAHLGWMIIILPFSS----PLTLLTLFTYLMMTFSLFSSFMLIRTTH--INSLSTSWA 234
Cdd:MTH00196 163 LFVGAIGALNQTKIKRLLAYSGIGHMGFVLWGIEIGSfesiQASLVYLFIYIIMSICVFSIILALNVYKnlIIEFSGLSR 242

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 662035233 235 KIPALTASVPLILLSLGGLPPLTGFLPKWLILQELTKQDLAPIATLAALSSLFSLYFYLRL 295
Cdd:MTH00196 243 RLPILAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRI 303
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-267 7.33e-21

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 90.84  E-value: 7.33e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233   23 STHWYLAWMGIEINTLAIIPLMTQNH-NPRTIEATTKYFFAQATASATLLFA--AVSNAFLTGGWDILQTNHPLT----- 94
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGYWGkSPRSSEAGMKYFLLTLLGSSILLFGisLMYNYTGTLSFDELSKALTGGlnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233   95 ----STLITLALAMKIGLAPLHSWMPEVMQGVSLLTGLTL-STWQKLAPLCLIYQIQPNSPS------VFTTLGLLSVIV 163
Cdd:pfam00361  81 llllFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLaATLVKAGGYGLIRRSLLYLPSspfiqqILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  164 GGWGGLNQIQLRKILAYSSIAHLGWMIIILpFSSPLTLLTLFTYLMMTFSLFSS--FMLI--------RTTHINSLSTSW 233
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIAL-GAGTIYGIQAAIFHLLTHGLFSAglFLCAgsviyrrvHTRNIRDYGGLA 239

                         250       260       270
                  ....*....|....*....|....*....|....
gi 662035233  234 AKIPALTASVPLILLSLGGLPPLTGFLPKWLILQ 267
Cdd:pfam00361 240 KTMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 9-295 5.62e-20

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 90.46  E-value: 5.62e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233   9 LIISLGLGTTMTFASTHWYLAWMGIEINTLAIIPLMTQNHNP-RTIEATTKYFFAQATASATLLFAAVSNAFLTGGWDIL 87
Cdd:MTH00199 102 LILIVALGSLLLVSSINWLSIYLAIELQTLTLFILVALKRDSaYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGETSIQ 181

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  88 QTNHPLTS----TLITLALAMKIGLAPLHSWMPEVMQGVSLLTGLTLSTWQKLAPLCLIYQIQPNSpSVFTTLGLLSVIV 163
Cdd:MTH00199 182 GINSILTGdvgkILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVT-NVVLICAVLSIIY 260

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233 164 GGWGGLNQIQLRKILAYSSIAHLGWMII---ILPFSSPLTLLTLFTYLM-MTFSLFSSFMLIRTTH--INSLSTSWAKIP 237
Cdd:MTH00199 261 GAIGALNQTKIKRLLAYSGIGHMGFILFgvaIGSFESIQASLIYMIIYViMSICSFSIILSLKLTKglIVEVSGLSRKNP 340

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 662035233 238 ALTASVPLILLSLGGLPPLTGFLPKWLILQELTKQDLAPIATLAALSSLFSLYFYLRL 295
Cdd:MTH00199 341 VIALTLALTFLSIAGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRV 398
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 15-299 1.72e-16

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 80.16  E-value: 1.72e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  15 LGTTMTFASTHWYLAWMGIEINTLAIIPL-MTQNHNPRTIEATTKYFFAQATASATLLFAAVSNAFLTGGWDILQ----- 88
Cdd:COG1007  113 LGMMLMASANDLLTLFLGLELLSLSLYVLvAFRRDDRRSSEAALKYFLLGALSSGFLLYGISLLYGATGSLNLAGiaaal 192

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  89 TNHPLTSTLITLALAM-------KIGLAPLHSWMPEVMQGVSLLTGLTLSTWQKLAPLCLIYQI-----QPNSPSVFTTL 156
Cdd:COG1007  193 AAGGANSPLLLLGLVLvlaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLRLlveafPGLAADWQLLL 272

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233 157 GLLSV---IVGGWGGLNQIQLRKILAYSSIAHLGWMIIILPFSSPLTLLTLFTYLM----MTFSLFSSFMLIR-----TT 224
Cdd:COG1007  273 AVLAVlsmTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLGVSAALFYLLaylfMNLGAFAVILLLSrkggeAE 352

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233 225 HINSLSTSWAKIPALTAS----------VPlillslgglpPLTGFLPKWLILQELTKQDLAPIATLAALSSLFSLYFYLR 294
Cdd:COG1007  353 EIEDLAGLARRSPLLALAmtifllslagIP----------PTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLR 422


                 ....*
gi 662035233 295 LSYTM 299
Cdd:COG1007  423 VVKAM 427
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 15-299 1.49e-15

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 77.11  E-value: 1.49e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  15 LGTTMTFASTHWYLAWMGIEINTLAIIPLMTQNHNPRTIEATTKYFFAQATASATLLFAAVSNAFLTGGWD-------IL 87
Cdd:COG0651  118 AGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNmadlaarLA 197

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  88 QTNHPLTST---LITLALAMKIGLAPLHSWMPEVMQ----GVS-LLTGLTLstwqKLAPLCLI---YQIQPNSPSVFT-- 154
Cdd:COG0651  198 ELDPGLLLAafaLLLVGFGIKAALFPLHFWLPDAYPaapsPVSaLLSGLLT----KVGVYAILrvlTLLFGADPALFLgt 273

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233 155 ---TLGLLSVIVGGWGGLNQIQLRKILAYSSIAHLGWMIIILPFSSPLTLLT----LFTYLMMTFSLFSSFMLIR----T 223
Cdd:COG0651  274 lllVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGalfhLLNHALAKALLFLAAGAIEratgT 353

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 662035233 224 THINSLSTSWAKIPALTASVPLILLSLGGLPPLTGFLPKWLILQELTKQDLAPIATLAALSSLFSLYFYLRLSYTM 299
Cdd:COG0651  354 RDLDKLGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAYFVRIFGRA 429
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 23-299 1.57e-14

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 74.21  E-value: 1.57e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233   23 STHWYLAWMGIEINTLAIIPLMT-QNHNPRTIEATTKYFFAQATASATLLFAAVSNAFLTGGWDILQTNHPLTST----- 96
Cdd:TIGR01770 121 SNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLLFLSNGmlnis 200

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233   97 -------LITLALAMKIGLAPLHSWMPEVMQGVSLLTGLTLSTWQKLAPLCLIYQIQPNSPSVFTT--------LGLLSV 161
Cdd:TIGR01770 201 llllgivLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYILFGFSEawqiflaiIAFLSM 280

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  162 IVGGWGGLNQIQLRKILAYSSIAHLGWMIIILPFSS----PLTLLTLFTYLMMTFSLFSSFMLIRTT------HINSLST 231
Cdd:TIGR01770 281 LIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTlegiKAVLFYIFIYALMSLGAFGVLSLLRSYkdewieYISDFAG 360

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 662035233  232 SWAKIPALTASVPLILLSLGGLPPLTGFLPKWLILQELTKQDLAPIATLAALSSLFSLYFYLRLSYTM 299
Cdd:TIGR01770 361 LFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVVKVM 428
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
15-316 1.84e-14

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 74.09  E-value: 1.84e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  15 LGTTMTFASTHWYLAWMGIEINTLAIIPL-MTQNHNPRTIEATTKYFFAQATASA--------------TLLFAAVSNAF 79
Cdd:PRK05777 114 LGMMVMVSANDLLTLFLGLELLSLPLYALaALRRDRRRSLEAAIKYFVLGALASGfllygmsllygatgSLSFAGIAKAL 193

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  80 LTGGwdilqTNHPLTST---LITLALAMKIGLAPLHSWMPEVMQGVSLLTGLTLSTWQKLAPLCLIYQI-----QPNSPS 151
Cdd:PRK05777 194 ADGS-----GNSLLLLFglvFLLVGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAVLLRLlvvafGGLSED 268

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233 152 ---VFTTLGLLSVIVGGWGGLNQIQLRKILAYSSIAHLGWMIIILPFSSPLTLLT----LFTYLMMTFSLFSSFMLIR-- 222
Cdd:PRK05777 269 wqqVLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLAAGTAEGYSAvlfyLLAYLFMTLGAFGVISLLRrk 348

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233 223 ---TTHINSLSTSWAKIPALTASVPLILLSLGGLPPLTGFLPKWLILQELTKQDLAPIATLAALSSLFSLYFYLRLSYTM 299
Cdd:PRK05777 349 ggeAESISDFAGLSKRSPLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFYYLRVIKLM 428

                        330
                 ....*....|....*..
gi 662035233 300 TLTMSPNNPTGTLPWRL 316
Cdd:PRK05777 429 YFDEPPRDAPVNWPLSA 445
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 9-191 6.74e-12

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 66.42  E-value: 6.74e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233   9 LIISLGLGTTMTFASTHWYLAWMGIEINTLAIIPLMTQNHNPRTI---------EATTKYFFAQATASATLLFAAVSNAF 79
Cdd:MTH00198 193 LVLIVGLGGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFGCALYFG 272

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  80 LTGGWDILQTnhPLTSTL----------------ITLALAMKIGLAPLHSWMPEVMQGVSLLTGLTLSTWQKLAPLCLIY 143
Cdd:MTH00198 273 FTGNEGMLGT--ILSATLettnielrqgslgylfITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILLT 350

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 662035233 144 QIQPNSpSVFTTLGLLSVIVGGWGGLNQIQLRKILAYSSIAHLGWMII 191
Cdd:MTH00198 351 SLVITS-KLLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFILI 397
ndhB CHL00049
NADH dehydrogenase subunit 2
 51-295 5.15e-09

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 57.32  E-value: 5.15e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  51 RTIEATTKYFFAQATASATLLFAAVSNAFLTGGWDILQ-----------TNHPLTS---TLITLALAMKIGLAPLHSWMP 116
Cdd:CHL00049 159 RSNEATMKYLLMGGASSSILVYGFSWLYGLSGGEIELQeivnglintqmYNSPGISialIFITVGIGFKLSLAPFHQWTP 238

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233 117 EVMQGVSLLTGLTLSTWQKLAPLCL--------IYQIQPNSPSVFTTLGLLSVIVGGWGGLNQIQLRKILAYSSIAHLGW 188
Cdd:CHL00049 239 DVYEGSPTPVVAFLSVTSKVAASALatrifdipFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGY 318

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233 189 MIIILPFSSPLTLLTLftylMMTFSLFSSFMLIR-------------TTHINSLSTSWAKIPALTASVPLILLSLGGLPP 255
Cdd:CHL00049 319 VIIGIIVGDSNDGYAS----MITYMLFYIFMNLGtfacivlfglrtgTDNIRDYAGLYTKDPFLALSLALCLLSLGGIPP 394

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 662035233 256 LTGFLPKWLILQELTKQDLAPIATLAALSSLFSLYFYLRL 295
Cdd:CHL00049 395 LAGFFGKLYLFWCGWQAGLYFLVSIGLLTSVISIYYYLKI 434
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 50-191 2.06e-08

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 55.33  E-value: 2.06e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233   50 PRTIEATTKYFFAQATASATLLFAAVSNAFLTGG-WDILQ-TNHPLTSTL-------ITLALAMKIGLAPLHSWMPEVMQ 120
Cdd:TIGR01972 152 PNRIYAAMKFFLYTLAGSLLMLLAILGLYFLGGGtFDLLElLNLPLPFGVqtwlflaFFIAFAVKVPLFPLHTWLPDAHV 231

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  121 -----GVSLLTGLTLstwqKLAP---LCLIYQIQPNSPSVFTT----LGLLSVIVGGWGGLNQIQLRKILAYSSIAHLGW 188
Cdd:TIGR01972 232 eaptaGSVILAGVLL----KMGTygfLRFNLPLFPDASLYFAPvlaaLGVIAIIYGALIALAQTDIKRLIAYSSISHMGF 307


                  ...
gi 662035233  189 MII 191
Cdd:TIGR01972 308 VLL 310
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 50-191 1.37e-07

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 52.78  E-value: 1.37e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  50 PRTIEATTKYFFAQATASATLLFAAVSNAFLTGGW--DILQ-TNHPLTST-------LITLALAMKIGLAPLHSWMPEVM 119
Cdd:COG1008  157 ERRIYAAIKFFLYTLAGSLLMLVAILALYFLAGALtfDIAElAAAPLPLTaqlllflAFFIAFAVKVPMFPFHTWLPDAH 236

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233 120 Q----GVS-LLTGLTL----------------STWQKLAPLCLIyqiqpnspsvfttLGLLSVIVGGWGGLNQIQLRKIL 178
Cdd:COG1008  237 VeaptAGSvLLAGVLLkmggygllrfalplfpEASAYFAPLLAA-------------LGVIGIIYGALVALAQTDLKRLI 303

                        170
                 ....*....|...
gi 662035233 179 AYSSIAHLGWMII 191
Cdd:COG1008  304 AYSSVSHMGFVLL 316
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 28-189 3.40e-07

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 51.85  E-value: 3.40e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  28 LAWMGIEINTLAIIPLMTQNHNPRTIEATTKYFF------AQATASATLLFAAVSNAFLTGGWDILQTN-----HPLTST 96
Cdd:PRK06458 132 LMWVAIEATTLSSALLVGIYRTRASLEAAWKYIIicsvgvAFALFGTILVYANAATVMGDGEMAILWTEllkhaSLLDPT 211

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  97 LITLALAM-------KIGLAPLHSWMP----EVMQGVS-LLTGLTLSTwqKLAPLCLIYQIQPNSP------SVFTTLGL 158
Cdd:PRK06458 212 LMKLAFVFlligfgtKVGLFPMHAWLPdahsEAPSPVSaLLSGVLLNV--ALYAVLRYYILIDAAIgsdfpgRLLLIFGL 289

                        170       180       190
                 ....*....|....*....|....*....|.
gi 662035233 159 LSVIVGGWGGLNQIQLRKILAYSSIAHLGWM 189
Cdd:PRK06458 290 LSVLVAAFFLLRQRDIKRLFAYSSIEHMGLI 320
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
49-191 8.58e-07

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 50.43  E-value: 8.58e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  49 NPRTIEATTKYFFAQATASATLLFAAVSNAFLTGGWDILQTNHPLTSTLITLALAM-----------KIGLAPLHSWMPE 117
Cdd:PRK02504 156 DPRSNEAALKYLLIGAASSAIFLYGSSLLYGLSGGSTQLSAIALALITSPSLGLALalvfviagiafKISAVPFHQWTPD 235

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233 118 VMQGVSLLTGLTLSTWQKLAPLCLIYQIQPNSPS--------VFTTLGLLSVIVGGWGGLNQIQLRKILAYSSIAHLGWM 189
Cdd:PRK02504 236 VYEGSPTPVVAFLSVGSKAAGFALAIRLLVTAFPsfdeqwklLFTALAILSMVLGNVVALAQTSMKRMLAYSSIGQAGFV 315


                 ..
gi 662035233 190 II 191
Cdd:PRK02504 316 MI 317
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 17-198 9.94e-07

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 50.14  E-value: 9.94e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  17 TTMTFASTHWYLAWMGIEINTLAIIPLMTQNHNPRTIEATTKYFFAQATA------SATLLFAAVSNAFLTG--GWDILQ 88
Cdd:PRK08676 115 ITFAFFSDNLALFWIFAELTTVFSAMLIAILSARENIDAALKYIFIASTAmifafiGLIFLFSLTRQALGTGtlNWTELA 194

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  89 TNHPLTS--------TLITLALAMKIGLAPLHSWMPEV-MQGVSLLTGLTLSTWQKLAPLCLIY--------QIQPNSPS 151
Cdd:PRK08676 195 AHASLLSpsvlgasfLFIFIGFLAKSGLVPFHTWLPAAyAKAPSVVSALLSGTVLNIGIYGILRlsallrqsGAAEQFSN 274

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 662035233 152 VFTTLGLLSVIVGGWGGLNQIQLRKILAYSSIAHLGWMIIILPFSSP 198
Cdd:PRK08676 275 VLIGLGIFSIAVAAFSMLSQRNLKKLIAFSSIEHMGLMLLGIGIGTP 321
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 50-191 1.04e-06

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 50.20  E-value: 1.04e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  50 PRTIEATTKYFFAQATASATLLFA----AVSNAFLTGGWDILQ-TNHPLTSTLITL-------ALAMKIGLAPLHSWMPE 117
Cdd:PRK05846 157 KNRIYAATKFFLYTLLGSLLMLVAiiylVVVYYNATGTFDIADlLNLPLPPGVQYWlflaffiAFAVKMPMFPLHTWLPD 236

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233 118 VMQ-----GVSLLTGLTLstwqKLAPLCLI---YQIQPNSPSVFT----TLGLLSVIVGGWGGLNQIQLRKILAYSSIAH 185
Cdd:PRK05846 237 AHVqaptaGSVLLAGILL----KMGAYGLLrfsLPLFPDASHEFApiiiTLGVIAIIYGALVALAQTDIKKLIAYSSISH 312


                 ....*.
gi 662035233 186 LGWMII 191
Cdd:PRK05846 313 MGFVTL 318
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-299 1.41e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 49.88  E-value: 1.41e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  33 IEINTLAIIPLMTQNHNPRTIEATTKYFFAQATASATLLFAAVSNAFLTGGWD------ILQTNHPLTST--LITLALAM 104
Cdd:PRK08375 135 LEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGVGLLYGVTGTLNmadlagALAENPTVVTAfgFVLLALAL 214

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233 105 KIGLAPLHSWMPEVMQGVS-LLTGLTLSTWQKLAPLCLI----------YQIQPNSPSVFTTLGLLSVIVGGWGGLNQIQ 173
Cdd:PRK08375 215 KAAVFPLHTWLPRAYPAAPpVVTALLSGLVTKVAVYALIriyftvfggdFRFALGLGWLLAVLALLSMLVGSLAALGQDD 294

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233 174 LRKILAYSSIAHLGWMIIILPFSSPLTLLTLFTYLM----MTFSLF-SSFMLIRTTH---INSLSTSWAKIPALTASVPL 245
Cdd:PRK08375 295 VKRVLAYSTVSQMGYILLGLALLTPLALAAGLLHLLhhalMKGALFlAAGAIEVTYGtrrLSELSGLGRRMPLTAAAFAV 374

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 662035233 246 ILLSLGGLPPLTGFLPKWLILQELTKQDLAPIATLAALSSLFSLYFYLRLSYTM 299
Cdd:PRK08375 375 ASLSLIGVPPTSGFVSKWYLVVGAVEAGQWLVLAVLLASSLLALLYFLRIWYRA 428
NADH_dehy_S2_C pfam06444
NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region ...
 290-340 3.57e-06

NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region specific to the eukaryotic NADH dehydrogenase subunit 2 protein and is found in conjunction with pfam00361.


Pssm-ID: 461914 [Multi-domain]  Cd Length: 51  Bit Score: 43.40  E-value: 3.57e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 662035233  290 YFYLRLSYTMTLTMSPNNPTGTLPWRLNPRHNTLPLALTTTTTIFLLPATP 340
Cdd:pfam06444   1 FFYLRLSYSTTLTLFPNTNNSKMKWRFNSTKNTLLLPTLTTLSILLLPLTP 51
ND4 MTH00217
NADH dehydrogenase subunit 4; Provisional
 100-224 1.76e-05

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214462 [Multi-domain]  Cd Length: 482  Bit Score: 46.20  E-value: 1.76e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233 100 LALAMKIGLAPLHSWMPEV-----MQGVSLLTGLTLstwqKLAPLCLI---YQIQPNSPSVFT----TLGLLSVIVGGWG 167
Cdd:MTH00217 214 LSLAIKIPKIPFHIWLPQAhveapVAGSVILAGVLL----KLGGYGFIrfsWPLLPEASEYFSpliqTLSLLAIIYGSLT 289

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 662035233 168 GLNQIQLRKILAYSSIAHLGWMIIILpFSSPLTLLTLFTYLMMTFSLFSSFMLIRTT 224
Cdd:MTH00217 290 TCRQVDLKRIIAYSSVAHMGLVTLGI-FSHTIQGLVAAIFLMLAHGLVSSALFIAVT 345
ND4 MTH00226
NADH dehydrogenase subunit 4; Provisional
 98-193 9.94e-05

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214466 [Multi-domain]  Cd Length: 505  Bit Score: 44.14  E-value: 9.94e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  98 ITLALAMKIGLAPLHSWMPEV-----MQGVSLLTGLTLST----WQKLAPLCLIYQIQPNSPSVFTtLGLLSVIVGGWGG 168
Cdd:MTH00226 236 IFLAMAVKIPIFPFHIWLPKAhveapVAGSVLLAGILLKLggygLVRLSWPILPLGAQNLAPAVIA-MGIVGIVYGSFAT 314

                         90       100
                 ....*....|....*....|....*
gi 662035233 169 LNQIQLRKILAYSSIAHLGWMIIIL 193
Cdd:MTH00226 315 CRQIDVKRLVAYSSVAHMGLVSITL 339
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 96-193 1.88e-04

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 43.22  E-value: 1.88e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  96 TLITLALAM----KIGLAPLHSWMPEVMQG---VSLL--------TGLTLstwqkLAPLCLIYQIQPNSPSVFTTLGLLS 160
Cdd:COG1009  211 TLILLLLLLgafgKSAQFPLHFWLPDAMEGptpVSALlhaatmvkAGVYL-----LARLSPLFALSPVWLTVVAIIGAIT 285

                         90       100       110
                 ....*....|....*....|....*....|...
gi 662035233 161 VIVGGWGGLNQIQLRKILAYSSIAHLGWMIIIL 193
Cdd:COG1009  286 ALFAALIALAQTDIKRVLAYSTVSQLGYMFLAL 318
PRK07363 PRK07363
NADH-quinone oxidoreductase subunit M;
55-191 2.16e-04

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 180945 [Multi-domain]  Cd Length: 501  Bit Score: 42.78  E-value: 2.16e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  55 ATTKYFFAQATASATLLFAAVSNAFLTGG----WDILQT-NHPLTSTLITLAL-----AMKIGLAPLHSWMP----EVMQ 120
Cdd:PRK07363 158 ASIKFLIYTAVSGLLVLAAFLGIVWLSGStsfdYDAISTqNLSLNTQLILLTGlllgfGIKIPLVPLHTWLPdaytEASP 237

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 662035233 121 GVSLLTGLTLSTWQKLAPLCLIYQIQPNSPSVFT----TLGLLSVIVGGWGGLNQIQLRKILAYSSIAHLGWMII 191
Cdd:PRK07363 238 AVAILLGGVLAKLGTYGLLRFGLQLFPQTWSLVApglaIIGTISVIYGALSAIAQKDIKRMVAYSSIGHMGYILV 312
PRK12644 PRK12644
putative monovalent cation/H+ antiporter subunit A; Reviewed
 90-193 2.65e-04

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237154 [Multi-domain]  Cd Length: 965  Bit Score: 42.99  E-value: 2.65e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  90 NHPLTSTLITLALAM-------KIGLAPLHSWMPEVMQ-----------------GVSLLTGLT-----LSTWQklaplc 140
Cdd:PRK12644 194 ADPPTGPAVSVAVVLilvgalsKSAIVPFHFWLPGAMAaptpvsaylhaaamvkaGIYLVARLApgfadVPVWR------ 267

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 662035233 141 liyqiqpnsPSVFTtLGLLSVIVGGWGGLNQIQLRKILAYSSIAHLGWMIIIL 193
Cdd:PRK12644 268 ---------PTVLV-LGLATMLLGGWRALRQHDLKLILAYGTVSQLGFLTVLV 310
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-299 4.06e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 42.01  E-value: 4.06e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  33 IEINTLAIIPLMT-QNHNPRTIEATTKYFFAQATASATLLFAAvsnAFLTGGWDIL---------QTNHPLTS----TLI 98
Cdd:PRK08376 150 LEIMSIASYALVAfRNDTWEAIEAGIKYMFVGSLASSMVLLGI---ALLYGQYGTLnmaylavkmSENPTVVAkialALF 226

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  99 TLALAMKIGLAPLHSWMP----EVMQGVS-LLTGLTLSTWQKLAPLCL-IYQIQPNS---PSVFTTLGLLSVIVGGWGGL 169
Cdd:PRK08376 227 IAGLAMKSGAVPVHMWLPdaypAAPSSISaMLLVIKQAGLYALARVLFsIYGPAINLatvGWVIIILGCLTMFVGVAMAV 306

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233 170 NQIQLRKILAYSSIAHLGWMII-----ILPFSSPLTLLTLFTY-----------LMMTFSLF----SSFMLIRTTHINSL 229
Cdd:PRK08376 307 VQKDVKRLLAYHSVSQIGYMLLglgvgLAALGDPAMASYGEIAlaggiyhivnhALYKALLFltagAVIYETGTRNLNEL 386

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 662035233 230 STSWAKIPALTASVPLILLSLGGLPPLTGFLPKWLILQelTKQDLAPI-ATLAALSSLFSLYFYLRLSYTM 299
Cdd:PRK08376 387 GGLARTMPKTTIAFLIGAAAIVGLPPFNGFASKWLIYE--SSALFNPIlGVIAMIGSVLTLASFVKVFHTA 455
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 55-191 4.66e-04

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 41.94  E-value: 4.66e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  55 ATTKYFFAQATASATLLFAAVSNAFLTGGW-----DILQTNHPLTSTLIT-----LALAMKIGLAPLHSWMP----EVMQ 120
Cdd:PRK12561 138 AATKFILYTALASIFILVAGLALALSGDTFtfdlaELGAKSYPLALELLLyagflIAFGVKLPIFPLHTWLPdahgEASA 217

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 662035233 121 GVS-LLTGLTLstwqKLAPLCLI---YQIQPNSPSVFT----TLGLLSVIVGGWGGLNQIQLRKILAYSSIAHLGWMII 191
Cdd:PRK12561 218 PVSmILAGVLL----KMGGYALIrfnVQMLPDAHVYFApalaILGVVNIIYGALNAFAQDNVKRRLAYSSVSHMGFVLL 292
ND5 MTH00032
NADH dehydrogenase subunit 5; Provisional
 111-193 8.15e-04

NADH dehydrogenase subunit 5; Provisional


Pssm-ID: 214407 [Multi-domain]  Cd Length: 669  Bit Score: 41.10  E-value: 8.15e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233 111 LHSWMPEVMQGVSLLTGLTLSTWQKLAPLCL------IYQIQPNSPSVFTTLGLLSVIVGGWGGLNQIQLRKILAYSSIA 184
Cdd:MTH00032 244 LHTWLPDAMEGPTPVSALIHAATMVTAGVFLmirsfpLFEKAPLTLLIITIFGALTAFFAATVGLVQNDLKKVIAYSTCS 323


                 ....*....
gi 662035233 185 HLGWMIIIL 193
Cdd:MTH00032 324 QLGYMVLII 332
ND5 MTH00020
NADH dehydrogenase subunit 5; Reviewed
 111-197 1.17e-03

NADH dehydrogenase subunit 5; Reviewed


Pssm-ID: 214400 [Multi-domain]  Cd Length: 610  Bit Score: 40.83  E-value: 1.17e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233 111 LHSWMPEVMQGVSLLTGLTLSTWQKLAPLCLIYQIQP---NSPS---VFTTLGLLSVIVGGWGGLNQIQLRKILAYSSIA 184
Cdd:MTH00020 229 LHTWLPDAMEGPTPVSALIHAATMVTAGVFLLIRSSPlfeQAPLaliIVTIVGSLTVFFAATVGLVQNDLKKVIAYSTCS 308

                         90
                 ....*....|...
gi 662035233 185 HLGWMIIILPFSS 197
Cdd:MTH00020 309 QLGYMVVACGLSH 321
PRK12662 PRK12662
putative monovalent cation/H+ antiporter subunit D; Reviewed
 98-266 2.65e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 183662 [Multi-domain]  Cd Length: 492  Bit Score: 39.33  E-value: 2.65e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  98 ITLALAMKIGLAPLHSWMPEVMQGVSLLTGLTLSTWQKLAPLCLIYQI------------QPNSPSVFTTLGLLSVIVGG 165
Cdd:PRK12662 215 IMVGLFIKAALFPFHKWLIQAYSEAPSFISVFFSGTSTKVMIYLIIRIvydvfkanfvftTLPFNNVFMILAALAIVFGS 294

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233 166 WGGLNQIQLRKILAYSSIAHLGWMIIILPFSSpLTLLTLFTYLMMTFSLFSS--FMLI-------RTTHINSLSTSWAKI 236
Cdd:PRK12662 295 VLAILSKDIKRIFAYSSISHIGYIILAVSLNT-YYGLAAAVAYIVNHSIVKSalFMVSgsisyhfGTTKLEDCLNLWKSM 373

                        170       180       190
                 ....*....|....*....|....*....|
gi 662035233 237 PALTASVPLILLSLGGLPPLTGFLPKWLIL 266
Cdd:PRK12662 374 PKITLAFVLLSLSLIGMPPTSGFVAKWYIL 403
ND4 MTH00204
NADH dehydrogenase subunit 4; Provisional
 100-226 4.11e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 164750 [Multi-domain]  Cd Length: 485  Bit Score: 38.89  E-value: 4.11e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233 100 LALAMKIGLAPLHSWMPEV-----MQGVSLLTGLTLstwqKLAPLCLI---YQIQPNSPSVFT----TLGLLSVIVGGWG 167
Cdd:MTH00204 217 LSLAVKIPQIPFHIWLPQAhveapVAGSVILAGILL----KLGGYGFLrfsWPLFPAASEYFAplivMLSVIAVIYGSLT 292

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 662035233 168 GLNQIQLRKILAYSSIAHLGWMIIILpFSSPLTLLTLFTYLMMTFSLFSSFMLIRTTHI 226
Cdd:MTH00204 293 TCRQVDFKRLIAYSSVAHMGLVPLGL-FTHTIEGLVAAVFLMLAHGFVSSALFIAVTFL 350
PRK07376 PRK07376
NADH-quinone oxidoreductase subunit L;
110-191 4.23e-03

NADH-quinone oxidoreductase subunit L;


Pssm-ID: 236005 [Multi-domain]  Cd Length: 673  Bit Score: 38.85  E-value: 4.23e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233 110 PLHSWMPEVMQGVSLLTGLTLSTWQKLAPLCLIYQIQP---NSPSVFTTL---GLLSVIVGGWGGLNQIQLRKILAYSSI 183
Cdd:PRK07376 245 PLHVWLPDAMEGPTPISALIHAATMVAAGVFLVARMYPvfeQFPAVMTVIawtGAITAFLGASIALTQNDIKKGLAYSTI 324


                 ....*...
gi 662035233 184 AHLGWMII 191
Cdd:PRK07376 325 SQLGYMVM 332
PRK02546 PRK02546
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 55-191 5.53e-03

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 235050 [Multi-domain]  Cd Length: 525  Bit Score: 38.53  E-value: 5.53e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  55 ATTKYFFAQATASATLLFAAVSNAFLTGG-----WDILQTNHPLTSTLIT-----LALAMKIGLAPLHSWMP----EVMQ 120
Cdd:PRK02546 166 AATKFILYTAGSSLFILLAALAMAFYGDTptfdmTALAAKDFGLGFQLLCyagllIAYGVKLPIVPLHTWLPdahgEATA 245

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 662035233 121 GVSLLTGLTLSTWQKLAPLCLIYQIQPNSPSVFT----TLGLLSVIVGGWGGLNQIQLRKILAYSSIAHLGWMII 191
Cdd:PRK02546 246 PVHMLLAGILLKMGGYALLRMNAGMLPDAHAQFAplliVLGVVNIIYAALTSFAQRNLKRKIAYSSISHMGFVLI 320
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
86-198 9.91e-03

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 37.76  E-value: 9.91e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662035233  86 ILQTNHPLTSTLITLA-----LAMKIGLAPLHSWMP----EVMQGVSLL-----------------TGLTLSTWQKLAPL 139
Cdd:PRK06473 194 LRSHTLPLSTQLLLLApilvgFGIKIPLVPFHTWLPdahvEASTPVSVLlagvllklgtygllrfgVGLFPEAWVYLAPW 273

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 662035233 140 cliyqiqpnspsvFTTLGLLSVIVGGWGGLNQIQLRKILAYSSIAHLGWMIIILPFSSP 198
Cdd:PRK06473 274 -------------LATWAVVSVLYGASCAIAQKDMKKMVAYSSIGHMGYILLAAAAATP 319
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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