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Conserved domains on  [gi|663508421|gb|AIE99100|]
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hypothetical protein [uncultured marine thaumarchaeote KM3_105_E03]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Pyr_excise super family cl46242
Pyrimidine dimer DNA glycosylase; Pyrimidine dimer DNA glycosylases excise pyrimidine dimers ...
 1-91 1.57e-07

Pyrimidine dimer DNA glycosylase; Pyrimidine dimer DNA glycosylases excise pyrimidine dimers by hydrolysis of the glycosylic bond of the 5' pyrimidine, followed by the intra-pyrimidine phosphodiester bond. Pyrimidine dimers are the major UV-lesions of DNA.


The actual alignment was detected with superfamily member pfam03013:

Pssm-ID: 480582  Cd Length: 81  Bit Score: 46.13  E-value: 1.57e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663508421    1 MNIFVLskNVKKCASYHCDQHVVKMILESAQMLStvcNLSGRKTEYkpafRNHPCTKWVHRSLsnwLWLRSLARELNNEF 80
Cdd:pfam03013   1 MRLWNL--HPEDSAEYLDRQHLLAQHRELLQIFG---VLLGEKKGY----RNHPHVKRFYGYL---EALAQYHLALVEEM 68

                          90
                  ....*....|..
gi 663508421   81 VNR-YSHTDSHK 91
Cdd:pfam03013  69 TRRgYNFNRPWI 80
 
Name Accession Description Interval E-value
Pyr_excise pfam03013
Pyrimidine dimer DNA glycosylase; Pyrimidine dimer DNA glycosylases excise pyrimidine dimers ...
 1-91 1.57e-07

Pyrimidine dimer DNA glycosylase; Pyrimidine dimer DNA glycosylases excise pyrimidine dimers by hydrolysis of the glycosylic bond of the 5' pyrimidine, followed by the intra-pyrimidine phosphodiester bond. Pyrimidine dimers are the major UV-lesions of DNA.


Pssm-ID: 460778  Cd Length: 81  Bit Score: 46.13  E-value: 1.57e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663508421    1 MNIFVLskNVKKCASYHCDQHVVKMILESAQMLStvcNLSGRKTEYkpafRNHPCTKWVHRSLsnwLWLRSLARELNNEF 80
Cdd:pfam03013   1 MRLWNL--HPEDSAEYLDRQHLLAQHRELLQIFG---VLLGEKKGY----RNHPHVKRFYGYL---EALAQYHLALVEEM 68

                          90
                  ....*....|..
gi 663508421   81 VNR-YSHTDSHK 91
Cdd:pfam03013  69 TRRgYNFNRPWI 80
 
Name Accession Description Interval E-value
Pyr_excise pfam03013
Pyrimidine dimer DNA glycosylase; Pyrimidine dimer DNA glycosylases excise pyrimidine dimers ...
 1-91 1.57e-07

Pyrimidine dimer DNA glycosylase; Pyrimidine dimer DNA glycosylases excise pyrimidine dimers by hydrolysis of the glycosylic bond of the 5' pyrimidine, followed by the intra-pyrimidine phosphodiester bond. Pyrimidine dimers are the major UV-lesions of DNA.


Pssm-ID: 460778  Cd Length: 81  Bit Score: 46.13  E-value: 1.57e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663508421    1 MNIFVLskNVKKCASYHCDQHVVKMILESAQMLStvcNLSGRKTEYkpafRNHPCTKWVHRSLsnwLWLRSLARELNNEF 80
Cdd:pfam03013   1 MRLWNL--HPEDSAEYLDRQHLLAQHRELLQIFG---VLLGEKKGY----RNHPHVKRFYGYL---EALAQYHLALVEEM 68

                          90
                  ....*....|..
gi 663508421   81 VNR-YSHTDSHK 91
Cdd:pfam03013  69 TRRgYNFNRPWI 80
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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