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Conserved domains on  [gi|663528462|gb|AIF18501|]
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putative DNA binding protein [uncultured marine group II/III euryarchaeote KM3_83_B05]

Protein Classification

helix-turn-helix domain-containing protein( domain architecture ID 10523064)

helix-turn-helix domain-containing protein similar to Halobacterium salinarum dimethyl sulfoxide (DMSO) reductase transcriptional activator, which is involved in activating dmsEABCD gene expression and is required for anaerobic respiration on DMSO

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DmsR COG3413
Predicted transcriptional regulator, contains HTH domain [General function prediction only];
156-213 2.17e-17

Predicted transcriptional regulator, contains HTH domain [General function prediction only];


:

Pssm-ID: 442639 [Multi-domain]  Cd Length: 143  Bit Score: 75.74  E-value: 2.17e-17
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 663528462 156 LSDKRMDVLQIAYSEGWYNTPREITLGELANKIGLGRSTVSEHLIKSESKIIQYFLEG 213
Cdd:COG3413   86 LTDRQREALETAYEMGYFEVPREATLEELAEELGISKSTLSEHLRRAERKLLEALLDE 143
 
Name Accession Description Interval E-value
DmsR COG3413
Predicted transcriptional regulator, contains HTH domain [General function prediction only];
156-213 2.17e-17

Predicted transcriptional regulator, contains HTH domain [General function prediction only];


Pssm-ID: 442639 [Multi-domain]  Cd Length: 143  Bit Score: 75.74  E-value: 2.17e-17
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 663528462 156 LSDKRMDVLQIAYSEGWYNTPREITLGELANKIGLGRSTVSEHLIKSESKIIQYFLEG 213
Cdd:COG3413   86 LTDRQREALETAYEMGYFEVPREATLEELAEELGISKSTLSEHLRRAERKLLEALLDE 143
HTH_10 pfam04967
HTH DNA binding domain;
156-207 2.85e-16

HTH DNA binding domain;


Pssm-ID: 282780 [Multi-domain]  Cd Length: 53  Bit Score: 69.95  E-value: 2.85e-16
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 663528462  156 LSDKRMDVLQIAYSEGWYNTPREITLGELANKIGLGRSTVSEHLIKSESKII 207
Cdd:pfam04967   1 LTDRQLEVLRLAYEMGYFDYPRRVTLKELAKELGISKSTLSEHLRRAESKLI 52
PRK13558 PRK13558
bacterio-opsin activator; Provisional
 156-212 3.18e-07

bacterio-opsin activator; Provisional


Pssm-ID: 237426 [Multi-domain]  Cd Length: 665  Bit Score: 50.22  E-value: 3.18e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 663528462 156 LSDKRMDVLQIAYSEGWYNTPREITLGELANKIGLGRSTVSEHLIKSESKIIQYFLE 212
Cdd:PRK13558 608 LTDRQLTALQKAYVSGYFEWPRRVEGEELAESMGISRSTFHQHLRAAERKLVGAFFD 664
 
Name Accession Description Interval E-value
DmsR COG3413
Predicted transcriptional regulator, contains HTH domain [General function prediction only];
156-213 2.17e-17

Predicted transcriptional regulator, contains HTH domain [General function prediction only];


Pssm-ID: 442639 [Multi-domain]  Cd Length: 143  Bit Score: 75.74  E-value: 2.17e-17
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 663528462 156 LSDKRMDVLQIAYSEGWYNTPREITLGELANKIGLGRSTVSEHLIKSESKIIQYFLEG 213
Cdd:COG3413   86 LTDRQREALETAYEMGYFEVPREATLEELAEELGISKSTLSEHLRRAERKLLEALLDE 143
HTH_10 pfam04967
HTH DNA binding domain;
156-207 2.85e-16

HTH DNA binding domain;


Pssm-ID: 282780 [Multi-domain]  Cd Length: 53  Bit Score: 69.95  E-value: 2.85e-16
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 663528462  156 LSDKRMDVLQIAYSEGWYNTPREITLGELANKIGLGRSTVSEHLIKSESKII 207
Cdd:pfam04967   1 LTDRQLEVLRLAYEMGYFDYPRRVTLKELAKELGISKSTLSEHLRRAESKLI 52
PRK13558 PRK13558
bacterio-opsin activator; Provisional
 156-212 3.18e-07

bacterio-opsin activator; Provisional


Pssm-ID: 237426 [Multi-domain]  Cd Length: 665  Bit Score: 50.22  E-value: 3.18e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 663528462 156 LSDKRMDVLQIAYSEGWYNTPREITLGELANKIGLGRSTVSEHLIKSESKIIQYFLE 212
Cdd:PRK13558 608 LTDRQLTALQKAYVSGYFEWPRRVEGEELAESMGISRSTFHQHLRAAERKLVGAFFD 664
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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