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Conserved domains on  [gi|674924248|gb|AIL31442|]
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spexin 2, partial [Anolis carolinensis]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Spexin super family cl21036
Neuropeptide secretory protein family, NPQ, spexin; Spexin, alternatively named NPQ, is a ...
 25-65 5.94e-09

Neuropeptide secretory protein family, NPQ, spexin; Spexin, alternatively named NPQ, is a peptide hormone and is derived from a pro-hormone. This family of proteins has a role in inducing stomach wall contraction and is expressed in the submucosal layer of the mouse oesophagus and stomach. Spexin, like most peptide hormones, is a ligand for G-protein coupled receptors. Spexin is also thought to have a role in controlling arterial blood pressure as well as salt and water balance.


The actual alignment was detected with superfamily member pfam15171:

Pssm-ID: 464543  Cd Length: 90  Bit Score: 47.62  E-value: 5.94e-09
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 674924248  25 APKSKLIARNWGPQSMLYLKGRYGRRYVaSDNEEECYLNDQ 65
Cdd:pfam15171  1 APQRLFERRNWTPQAMLYLKGAQGRRFI-SDQSRRKDLSDR 40
 
Name Accession Description Interval E-value
Spexin pfam15171
Neuropeptide secretory protein family, NPQ, spexin; Spexin, alternatively named NPQ, is a ...
 25-65 5.94e-09

Neuropeptide secretory protein family, NPQ, spexin; Spexin, alternatively named NPQ, is a peptide hormone and is derived from a pro-hormone. This family of proteins has a role in inducing stomach wall contraction and is expressed in the submucosal layer of the mouse oesophagus and stomach. Spexin, like most peptide hormones, is a ligand for G-protein coupled receptors. Spexin is also thought to have a role in controlling arterial blood pressure as well as salt and water balance.


Pssm-ID: 464543  Cd Length: 90  Bit Score: 47.62  E-value: 5.94e-09
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 674924248  25 APKSKLIARNWGPQSMLYLKGRYGRRYVaSDNEEECYLNDQ 65
Cdd:pfam15171  1 APQRLFERRNWTPQAMLYLKGAQGRRFI-SDQSRRKDLSDR 40
 
Name Accession Description Interval E-value
Spexin pfam15171
Neuropeptide secretory protein family, NPQ, spexin; Spexin, alternatively named NPQ, is a ...
 25-65 5.94e-09

Neuropeptide secretory protein family, NPQ, spexin; Spexin, alternatively named NPQ, is a peptide hormone and is derived from a pro-hormone. This family of proteins has a role in inducing stomach wall contraction and is expressed in the submucosal layer of the mouse oesophagus and stomach. Spexin, like most peptide hormones, is a ligand for G-protein coupled receptors. Spexin is also thought to have a role in controlling arterial blood pressure as well as salt and water balance.


Pssm-ID: 464543  Cd Length: 90  Bit Score: 47.62  E-value: 5.94e-09
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 674924248  25 APKSKLIARNWGPQSMLYLKGRYGRRYVaSDNEEECYLNDQ 65
Cdd:pfam15171  1 APQRLFERRNWTPQAMLYLKGAQGRRFI-SDQSRRKDLSDR 40
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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