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Conserved domains on  [gi|972903556|gb|ALW82800|]
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NADH dehydrogenase subunit 1, partial (mitochondrion) [Plestiodon tetragrammus]

Protein Classification

complex I subunit 1 family protein( domain architecture ID 103)

complex I subunit 1 family protein similar to NADH dehydrogenase subunit 1, which is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

EC:  7.1.1.-
Gene Ontology:  GO:0016655|GO:0016020
PubMed:  23417064|24059520
SCOP:  4005664

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK06076 super family cl00469
NADH-quinone oxidoreductase subunit NuoH;
1-99 2.18e-55

NADH-quinone oxidoreductase subunit NuoH;


The actual alignment was detected with superfamily member MTH00111:

Pssm-ID: 469782  Cd Length: 323  Bit Score: 173.93  E-value: 2.18e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972903556   1 GPFALFFLAEYANILMMNTLTCILFINPG-MTAPPDTFPMNLMLKASALTILFLWARASYPRFRYDQLMHLLWKNFLPIT 79
Cdd:MTH00111 223 GPFALFFLAEYANILLMNTLTTILFLNPStLNLPPELFTINLMTKTLLLTSGFLWIRASYPRFRYDQLMHLLWKQFLPLT 302

                         90       100
                 ....*....|....*....|
gi 972903556  80 LALFLWHTSFPTTLSGLPPQ 99
Cdd:MTH00111 303 LALCLWHTSMPISLAGLPPQ 322
 
Name Accession Description Interval E-value
ND1 MTH00111
NADH dehydrogenase subunit 1; Provisional
 1-99 2.18e-55

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 214422  Cd Length: 323  Bit Score: 173.93  E-value: 2.18e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972903556   1 GPFALFFLAEYANILMMNTLTCILFINPG-MTAPPDTFPMNLMLKASALTILFLWARASYPRFRYDQLMHLLWKNFLPIT 79
Cdd:MTH00111 223 GPFALFFLAEYANILLMNTLTTILFLNPStLNLPPELFTINLMTKTLLLTSGFLWIRASYPRFRYDQLMHLLWKQFLPLT 302

                         90       100
                 ....*....|....*....|
gi 972903556  80 LALFLWHTSFPTTLSGLPPQ 99
Cdd:MTH00111 303 LALCLWHTSMPISLAGLPPQ 322
NADHdh pfam00146
NADH dehydrogenase;
2-85 2.09e-22

NADH dehydrogenase;


Pssm-ID: 459690  Cd Length: 302  Bit Score: 87.91  E-value: 2.09e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972903556    2 PFALFFLAEYANILMMNTLTCILFINPGMTAPPDTFPMNLMLKASALTILFLWARASYPRFRYDQLMHLLWKNFLPITLA 81
Cdd:pfam00146 217 RFALFFLAEYANMFLMSALAVTLFLGGWLGPFPLPGLLWFLLKVFFVFFLFIWIRATLPRFRYDQLMRLGWKVLLPLSLA 296


                  ....
gi 972903556   82 LFLW 85
Cdd:pfam00146 297 NLLL 300
NuoH COG1005
NADH:ubiquinone oxidoreductase subunit 1 (chain H) [Energy production and conversion]; NADH: ...
 3-85 2.24e-20

NADH:ubiquinone oxidoreductase subunit 1 (chain H) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 1 (chain H) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440629  Cd Length: 329  Bit Score: 82.87  E-value: 2.24e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972903556   3 FALFFLAEYANILMMNTLTCILFI----NPGMTAPPDTFP--MNLMLKASALTILFLWARASYPRFRYDQLMHLLWKNFL 76
Cdd:COG1005  232 FALFFLAEYANMFLVSALATTLFLggwlGPFPILPLGGLPgiLWFLLKTLFFIFFFIWVRATLPRYRYDQLMRLGWKVLL 311


                 ....*....
gi 972903556  77 PITLALFLW 85
Cdd:COG1005  312 PLSLVNLVL 320
 
Name Accession Description Interval E-value
ND1 MTH00111
NADH dehydrogenase subunit 1; Provisional
 1-99 2.18e-55

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 214422  Cd Length: 323  Bit Score: 173.93  E-value: 2.18e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972903556   1 GPFALFFLAEYANILMMNTLTCILFINPG-MTAPPDTFPMNLMLKASALTILFLWARASYPRFRYDQLMHLLWKNFLPIT 79
Cdd:MTH00111 223 GPFALFFLAEYANILLMNTLTTILFLNPStLNLPPELFTINLMTKTLLLTSGFLWIRASYPRFRYDQLMHLLWKQFLPLT 302

                         90       100
                 ....*....|....*....|
gi 972903556  80 LALFLWHTSFPTTLSGLPPQ 99
Cdd:MTH00111 303 LALCLWHTSMPISLAGLPPQ 322
ND1 MTH00071
NADH dehydrogenase subunit 1; Provisional
 1-99 2.90e-48

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 214418  Cd Length: 322  Bit Score: 155.55  E-value: 2.90e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972903556   1 GPFALFFLAEYANILMMNTLTCILFINPGMTAP-PDTFPMNLMLKASALTILFLWARASYPRFRYDQLMHLLWKNFLPIT 79
Cdd:MTH00071 223 GPFALFFLAEYANILMMNTLSTILFLGSTYNHLqPELSTMNLMIKASILSMLFLWVRASYPRFRYDQLMHLVWKNFLPIT 302

                         90       100
                 ....*....|....*....|
gi 972903556  80 LALFLWHTSFPTTLSGLPPQ 99
Cdd:MTH00071 303 LAMTIFHISLPISTLGIPPM 322
ND1 MTH00134
NADH dehydrogenase subunit 1; Provisional
 1-99 2.46e-47

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 177192  Cd Length: 324  Bit Score: 153.22  E-value: 2.46e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972903556   1 GPFALFFLAEYANILMMNTLTCILFINPG-MTAPPDTFPMNLMLKASALTILFLWARASYPRFRYDQLMHLLWKNFLPIT 79
Cdd:MTH00134 224 GPFALFFLAEYANILLMNTLSAILFLGAShIPTLPELTTINLMTKAALLSVVFLWVRASYPRFRYDQLMHLVWKNFLPLT 303

                         90       100
                 ....*....|....*....|
gi 972903556  80 LALFLWHTSFPTTLSGLPPQ 99
Cdd:MTH00134 304 LALVIWHLALPIAFAGLPPQ 323
ND1 MTH00104
NADH dehydrogenase subunit 1; Provisional
 1-99 2.24e-43

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 177166  Cd Length: 318  Bit Score: 142.84  E-value: 2.24e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972903556   1 GPFALFFLAEYANILMMNTLTCILFINPG-MTAPPDTFPMNLMLKASALTILFLWARASYPRFRYDQLMHLLWKNFLPIT 79
Cdd:MTH00104 218 GPFALFFMAEYANIIMMNALTTILFLGAFhNPYMPELYTTNFTIKTLLLTILFLWIRASYPRFRYDQLMHLLWKNFLPLT 297

                         90       100
                 ....*....|....*....|
gi 972903556  80 LALFLWHTSFPTTLSGLPPQ 99
Cdd:MTH00104 298 LALCMWHISLPIMTASIPPQ 317
ND1 MTH00218
NADH dehydrogenase subunit 1; Provisional
 1-98 6.29e-35

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 214463  Cd Length: 311  Bit Score: 120.79  E-value: 6.29e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972903556   1 GPFALFFLAEYANILMMNTLTCILFINPGMTAppdtfpMNLMLKASALTILFLWARASYPRFRYDQLMHLLWKNFLPITL 80
Cdd:MTH00218 220 GPFALFFLAEYMNILFMNTLSVILFLGTSLTT------INLMLKATLLVFLFLWVRASLPRFRYDQLMHLAWKNFLPLSL 293

                         90
                 ....*....|....*...
gi 972903556  81 ALFLWHTSFPTTLSGLPP 98
Cdd:MTH00218 294 ALLLLHTSLPLSFASLPP 311
ND1 MTH00040
NADH dehydrogenase subunit 1; Validated
 1-98 3.22e-33

NADH dehydrogenase subunit 1; Validated


Pssm-ID: 214409  Cd Length: 323  Bit Score: 116.61  E-value: 3.22e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972903556   1 GPFALFFLAEYANILMMNTLTCILFINPGMTAPPdTFPMNLM---LKASALTILFLWARASYPRFRYDQLMHLLWKNFLP 77
Cdd:MTH00040 222 GPFALFFIAEYANIIFMNLLSVILFLGGGSPFNE-IFPINIIivgIKTTFLVFLFLWVRASYPRFRYDQLMFLTWKNYLP 300

                         90       100
                 ....*....|....*....|.
gi 972903556  78 ITLALFLWHTSFPTTLSGLPP 98
Cdd:MTH00040 301 LSIGLLIFYLLLLSLLNILPP 321
ND1 MTH00143
NADH dehydrogenase subunit 1; Provisional
 1-84 5.87e-23

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 177201  Cd Length: 307  Bit Score: 89.54  E-value: 5.87e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972903556   1 GPFALFFLAEYANILMMNTLTCILFINpGMTAPPDTFPMNLMLKASALTILFLWARASYPRFRYDQLMHLLWKNFLPITL 80
Cdd:MTH00143 219 GGFALLFLAEYANILFMSLLTVVLFFG-GSSVLFLLGGVVFMFKVLFFAFLFIWVRASYPRFRYDLLMMLCWKSFLPFSL 297


                 ....
gi 972903556  81 ALFL 84
Cdd:MTH00143 298 SILV 301
ND1 MTH00195
NADH dehydrogenase subunit 1; Provisional
 1-95 9.09e-23

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 214452  Cd Length: 307  Bit Score: 89.03  E-value: 9.09e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972903556   1 GPFALFFLAEYANILMMNTLTCILFINPGMTappdtfpMNLMLKASALTILFLWARASYPRFRYDQLMHLLWKNFLPITL 80
Cdd:MTH00195 220 GPFALIFMAEYSNIIFMSVLTTILFLGGGGT-------IIVALKSLFLSFCFLWVRGSLPRFRYDQLMHLTWKCYLPLIL 292

                         90
                 ....*....|....*
gi 972903556  81 ALFLWHTSFPTTLSG 95
Cdd:MTH00195 293 SLLIPLAAIPFALNS 307
ND1 MTH00216
NADH dehydrogenase subunit 1; Provisional
 3-98 1.18e-22

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 164761  Cd Length: 327  Bit Score: 89.02  E-value: 1.18e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972903556   3 FALFFLAEYANILMMNTLTCILFINPGMTAPPDTFPMNLM--LKASALTILFLWARASYPRFRYDQLMHLLWKNFLPITL 80
Cdd:MTH00216 229 FALFFLAEYAHIILMSCLTTILFLGGWLSPIKYFKGGAGWfgLKVVFIIFLFIWVRASFPRIRYDQLMALLWKSYLPLSL 308

                         90
                 ....*....|....*...
gi 972903556  81 ALFLWHTSFPTTLSGLPP 98
Cdd:MTH00216 309 GVVIFVASVLFGFNGPPP 326
NADHdh pfam00146
NADH dehydrogenase;
2-85 2.09e-22

NADH dehydrogenase;


Pssm-ID: 459690  Cd Length: 302  Bit Score: 87.91  E-value: 2.09e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972903556    2 PFALFFLAEYANILMMNTLTCILFINPGMTAPPDTFPMNLMLKASALTILFLWARASYPRFRYDQLMHLLWKNFLPITLA 81
Cdd:pfam00146 217 RFALFFLAEYANMFLMSALAVTLFLGGWLGPFPLPGLLWFLLKVFFVFFLFIWIRATLPRFRYDQLMRLGWKVLLPLSLA 296


                  ....
gi 972903556   82 LFLW 85
Cdd:pfam00146 297 NLLL 300
ND1 MTH00054
NADH dehydrogenase subunit 1; Provisional
 3-98 4.24e-22

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 177127  Cd Length: 324  Bit Score: 87.48  E-value: 4.24e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972903556   3 FALFFLAEYANILMMNTLTCILFI----NPGMTAPPDTFPMNLMLKASALTILFLWARASYPRFRYDQLMHLLWKNFLPI 78
Cdd:MTH00054 224 FALFFLAEYCHIILMSTFGVILFLggwlVISGPTSYFSNFVWFGIKIALIIFLFIWIRASYPRIRYDQLMALLWKSYLPL 303

                         90       100
                 ....*....|....*....|
gi 972903556  79 TLALFLWHTSFPTTLSGLPP 98
Cdd:MTH00054 304 SLAFVVLVSGILIGFNALPP 323
ND1 MTH00225
NADH dehydrogenase subunit 1; Provisional
 1-89 1.36e-20

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 214465  Cd Length: 305  Bit Score: 83.16  E-value: 1.36e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972903556   1 GPFALFFLAEYANILMMNTLTCILFINPGMtappDTFPMNLMLKASALTILFLWARASYPRFRYDQLMHLLWKNFLPITL 80
Cdd:MTH00225 219 GGFALIFMAEYGSILFMSMLTSILFFGGFF----VTIDLFLILKIMLLAFWFIWVRGVLPRMRYDKLMSLTWKSFLPLSL 294


                 ....*....
gi 972903556  81 ALFLWHTSF 89
Cdd:MTH00225 295 AYLFMVLII 303
NuoH COG1005
NADH:ubiquinone oxidoreductase subunit 1 (chain H) [Energy production and conversion]; NADH: ...
 3-85 2.24e-20

NADH:ubiquinone oxidoreductase subunit 1 (chain H) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 1 (chain H) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440629  Cd Length: 329  Bit Score: 82.87  E-value: 2.24e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972903556   3 FALFFLAEYANILMMNTLTCILFI----NPGMTAPPDTFP--MNLMLKASALTILFLWARASYPRFRYDQLMHLLWKNFL 76
Cdd:COG1005  232 FALFFLAEYANMFLVSALATTLFLggwlGPFPILPLGGLPgiLWFLLKTLFFIFFFIWVRATLPRYRYDQLMRLGWKVLL 311


                 ....*....
gi 972903556  77 PITLALFLW 85
Cdd:COG1005  312 PLSLVNLVL 320
ND1 MTH00193
NADH dehydrogenase subunit 1; Provisional
 1-89 3.01e-18

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 177241  Cd Length: 306  Bit Score: 76.73  E-value: 3.01e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972903556   1 GPFALFFLAEYANILMMNTLTCILFINPgmtappDTFPMNLMLKASALTILFLWARASYPRFRYDQLMHLLWKNFLPITL 80
Cdd:MTH00193 220 GGFALIFLAEYSSILFMSMLFVLMFLGG------DLLSLLFYLKLLFISFLFIWVRGTLPRFRYDKLMYLAWKSFLPLSL 293


                 ....*....
gi 972903556  81 ALFLWHTSF 89
Cdd:MTH00193 294 NYLLFFFGL 302
ND1 MTH00029
NADH dehydrogenase subunit 1; Provisional
 3-98 6.81e-18

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 177108  Cd Length: 343  Bit Score: 76.21  E-value: 6.81e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972903556   3 FALFFLAEYANILMMNTLTCILFIN---PGMTAPPDTFPMNLML--------------KASALTILFLWARASYPRFRYD 65
Cdd:MTH00029 229 FALFFLAEYSNIILMSCMMTIFFLGgwlSPLDGIPTPPEAFSIFeqiasskssfwfftKSSIFILFFIWSRASFPRIRYD 308

                         90       100       110
                 ....*....|....*....|....*....|...
gi 972903556  66 QLMHLLWKNFLPITLALFLWHTSFPTTLSGLPP 98
Cdd:MTH00029 309 QLMKLLWKTYLPLSLGLVILTAGILIGFNGVPP 341
PRK06076 PRK06076
NADH-quinone oxidoreductase subunit NuoH;
2-85 8.39e-18

NADH-quinone oxidoreductase subunit NuoH;


Pssm-ID: 235692  Cd Length: 322  Bit Score: 76.00  E-value: 8.39e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972903556   2 PFALFFLAEYANILMMNTLTCILFIN------PGMTAPPDTFPMnlMLKASALTILFLWARASYPRFRYDQLMHLLWKNF 75
Cdd:PRK06076 231 KFGLFFLGEYINMILVSALITTLFLGgwlppfPLGGGIPGAIWF--VLKVAFFVFLFIWLRATLPRYRYDQLMRLGWKVL 308

                         90
                 ....*....|
gi 972903556  76 LPITLALFLW 85
Cdd:PRK06076 309 LPLSLVNLLL 318
ND1 MTH00010
NADH dehydrogenase subunit 1; Validated
 1-84 5.86e-16

NADH dehydrogenase subunit 1; Validated


Pssm-ID: 164586  Cd Length: 311  Bit Score: 70.58  E-value: 5.86e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972903556   1 GPFALFFLAEYANILMMNTLTCILFINpgmTAPPDTF-PMNLMLKASALTILFLWARASYPRFRYDQLMHLLWKNFLPIT 79
Cdd:MTH00010 220 GLFALIFMAEYANILIMSLFTSVFFTS---FIPSIFIsDLMLILKTVFLAFLFIWIRATFPRMRYDRLMNLTWKSFLPMS 296


                 ....*
gi 972903556  80 LALFL 84
Cdd:MTH00010 297 LTSLM 301
ND1 MTH00090
NADH dehydrogenase subunit 1; Provisional
 3-84 1.96e-09

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 177153  Cd Length: 284  Bit Score: 52.59  E-value: 1.96e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972903556   3 FALFFLAEYANILMMNTLTCILFinpgmtappdtFPMNLMLKASALTILfLWARASYPRFRYDQLMHLLWKNFLPITLAL 82
Cdd:MTH00090 208 FVLLFLSEYGSLIFFSVLTSVLF-----------FKFSFLMLFLIFSLL-IFIRSSYPRFRYDMMMSMFWFKFLPLSLIF 275


                 ..
gi 972903556  83 FL 84
Cdd:MTH00090 276 LG 277
ndhA CHL00032
NADH dehydrogenase subunit 1
 3-89 7.78e-06

NADH dehydrogenase subunit 1


Pssm-ID: 214341  Cd Length: 363  Bit Score: 42.63  E-value: 7.78e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972903556   3 FALFFLAEYANILMMNTLTCILF-----INPGMTAPPDTFPMNLMLKASALTI----------LFLW----ARASYPRFR 63
Cdd:CHL00032 253 FGLFYVASYLNLLVSSLFVTVLYlggwnLSIPYIFIPELFEINKTGGVFGTTIgifitlaktyLFLFisitTRWTLPRLR 332

                         90       100
                 ....*....|....*....|....*.
gi 972903556  64 YDQLMHLLWKNFLPITLALFLWHTSF 89
Cdd:CHL00032 333 MDQLLNLGWKFLLPISLGNLLLTTSF 358
ND1 MTH00058
NADH dehydrogenase subunit 1; Provisional
 2-84 1.00e-04

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 177130  Cd Length: 293  Bit Score: 39.14  E-value: 1.00e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972903556   2 PFALFFLAEYANILMMNTLTCILFINPGMtappdtfpmnLMLKASALTILFLWARASYPRFRYDQLMHLLWKNFLPITLA 81
Cdd:MTH00058 218 YFTCLFACEYLIIFIFSWLGSVLFFGGGF----------VSIMLLFHLLFFMWARATLPRVRYDYFVNFFWEYCLVLLIL 287


                 ...
gi 972903556  82 LFL 84
Cdd:MTH00058 288 SLF 290
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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