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Conserved domains on  [gi|1018446923|gb|AMY60830|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Microgale pusilla]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475899)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-347 4.44e-154

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 436.20  E-value: 4.44e-154
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923   1 MNPIVTIIIFTTLIMGTLIAMISSHWLMTWIGLEMNMFAIIPLIMKSHSPRTTEAATKYFLIQASASMMLLLAASLNFME 80
Cdd:MTH00105    1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923  81 TGQWTLTSLESSLSSTILLISLMMKLGMAPFHFWVPEVTQGTKLSTGLIILTWQKLAPLSIMYQIHPSLNPNIMLTSAVL 160
Cdd:MTH00105   81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 161 SILVGGWGGLNQTQLRKIMAYSSIAHMGWMAAVVVFNPSLMLLNLLLYIIFTLAMFTILMNCHSTSTSTLSMTWNNYPLM 240
Cdd:MTH00105  161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 241 TTMMLTVLMSMGGLPPLSGFIPKWLIMDELIKNNNIMLSTTMAVMALLNLYFYMRLIYASSLTLFPSNNNIKFKWKINTP 320
Cdd:MTH00105  241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                         330       340
                  ....*....|....*....|....*..
gi 1018446923 321 HKIALLPTMLTLSTLILPLTPMIYILN 347
Cdd:MTH00105  321 KPMTLLPTLIILSTMLLPLTPMLSILE 347
 
Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-347 4.44e-154

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 436.20  E-value: 4.44e-154
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923   1 MNPIVTIIIFTTLIMGTLIAMISSHWLMTWIGLEMNMFAIIPLIMKSHSPRTTEAATKYFLIQASASMMLLLAASLNFME 80
Cdd:MTH00105    1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923  81 TGQWTLTSLESSLSSTILLISLMMKLGMAPFHFWVPEVTQGTKLSTGLIILTWQKLAPLSIMYQIHPSLNPNIMLTSAVL 160
Cdd:MTH00105   81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 161 SILVGGWGGLNQTQLRKIMAYSSIAHMGWMAAVVVFNPSLMLLNLLLYIIFTLAMFTILMNCHSTSTSTLSMTWNNYPLM 240
Cdd:MTH00105  161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 241 TTMMLTVLMSMGGLPPLSGFIPKWLIMDELIKNNNIMLSTTMAVMALLNLYFYMRLIYASSLTLFPSNNNIKFKWKINTP 320
Cdd:MTH00105  241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                         330       340
                  ....*....|....*....|....*..
gi 1018446923 321 HKIALLPTMLTLSTLILPLTPMIYILN 347
Cdd:MTH00105  321 KPMTLLPTLIILSTMLLPLTPMLSILE 347
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 6-299 6.27e-29

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 116.37  E-value: 6.27e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923   6 TIIIFTTLIMGTLIAmiSSHWLMTWIGLEMNMFAIIPLI-MKSHSPRTTEAATKYFLIQASASMMLLLAASLNFMETGQW 84
Cdd:COG1007   106 ALLLFATLGMMLMAS--ANDLLTLFLGLELLSLSLYVLVaFRRDDRRSSEAALKYFLLGALSSGFLLYGISLLYGATGSL 183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923  85 TLTSLESSLSSTILLISLMM------------KLGMAPFHFWVPEVTQGTKLSTGLIILTWQKLAPLS----IMYQIHPS 148
Cdd:COG1007   184 NLAGIAAALAAGGANSPLLLlglvlvlaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAallrLLVEAFPG 263

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 149 LNP---NIMLTSAVLSILVGGWGGLNQTQLRKIMAYSSIAHMGWM-AAVVVFNP---SLMLLNLLLYIIFTLAMFTILMn 221
Cdd:COG1007   264 LAAdwqLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLlLGLAAGTPlgvSAALFYLLAYLFMNLGAFAVIL- 342

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 222 cHSTSTSTLSMTWNNY-------PLMTTMMLTVLMSMGGLPPLSGFIPKWLIMDELIKNNNIMLSTTMAVMALLNLYFYM 294
Cdd:COG1007   343 -LLSRKGGEAEEIEDLaglarrsPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYL 421


                  ....*
gi 1018446923 295 RLIYA 299
Cdd:COG1007   422 RVVKA 426
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 4-297 9.74e-23

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 98.48  E-value: 9.74e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923   4 IVTIIIFTTLimGTLIAMISSHWLMTWIGLEMNMFAIIPLI-MKSHSPRTTEAATKYFLIQASASMMLLLAASLNFMETG 82
Cdd:TIGR01770 104 FYILLLFALL--GIFLLVSSNDLLSIYLGLELQSLCFYVLAgLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTG 181

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923  83 QWTLTSLESSLSSTILLISL------------MMKLGMAPFHFWVPEVTQGTKLSTGLIILTWQKLAPLSIMYQIHPSL- 149
Cdd:TIGR01770 182 SLNFEDLLLFLSNGMLNISLlllgivlilvglLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYIl 261

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 150 ------NPNIMLTSAVLSILVGGWGGLNQTQLRKIMAYSSIAHMGWMAAVVVFNP----SLMLLNLLLYIIFTLAMFTIL 219
Cdd:TIGR01770 262 fgfseaWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTlegiKAVLFYIFIYALMSLGAFGVL 341

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 220 MNchstsTSTLSMTWNNY-----------PLMTTMMLTVLMSMGGLPPLSGFIPKWLIMDELIKNNNIMLSTTMAVMALL 288
Cdd:TIGR01770 342 SL-----LRSYKDEWIEYisdfaglfktnPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVI 416


                  ....*....
gi 1018446923 289 NLYFYMRLI 297
Cdd:TIGR01770 417 GAFYYLRVV 425
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-267 7.75e-21

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 90.84  E-value: 7.75e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923  23 SSHWLMTWIGLEMNMFAIIPLI-MKSHSPRTTEAATKYFLIQASASMMLLLAASLNFMETGQWTLTSLESSLSSTILLIS 101
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKALTGGLNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 102 LMM-----------KLGMAPFHFWVPEVTQGTKLSTGLIIL-TWQKLAPLSIM---YQIHPSLN--PNIMLTSAVLSILV 164
Cdd:pfam00361  81 LLLlfllilvgflfKSAQVPFHTWLPDAYEGAPTPVSALLAaTLVKAGGYGLIrrsLLYLPSSPfiQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 165 GGWGGLNQTQLRKIMAYSSIAHMGWM----AAVVVFNPSLMLLNLLLYIIFTLAMF-----TILMNCHSTSTSTLSMTWN 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMlialGAGTIYGIQAAIFHLLTHGLFSAGLFlcagsVIYRRVHTRNIRDYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|..
gi 1018446923 236 NYPLMTTMMLTVLMSMGGLPPLSGFIPKWLIM 267
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLIL 272
 
Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-347 4.44e-154

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 436.20  E-value: 4.44e-154
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923   1 MNPIVTIIIFTTLIMGTLIAMISSHWLMTWIGLEMNMFAIIPLIMKSHSPRTTEAATKYFLIQASASMMLLLAASLNFME 80
Cdd:MTH00105    1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923  81 TGQWTLTSLESSLSSTILLISLMMKLGMAPFHFWVPEVTQGTKLSTGLIILTWQKLAPLSIMYQIHPSLNPNIMLTSAVL 160
Cdd:MTH00105   81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 161 SILVGGWGGLNQTQLRKIMAYSSIAHMGWMAAVVVFNPSLMLLNLLLYIIFTLAMFTILMNCHSTSTSTLSMTWNNYPLM 240
Cdd:MTH00105  161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 241 TTMMLTVLMSMGGLPPLSGFIPKWLIMDELIKNNNIMLSTTMAVMALLNLYFYMRLIYASSLTLFPSNNNIKFKWKINTP 320
Cdd:MTH00105  241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                         330       340
                  ....*....|....*....|....*..
gi 1018446923 321 HKIALLPTMLTLSTLILPLTPMIYILN 347
Cdd:MTH00105  321 KPMTLLPTLIILSTMLLPLTPMLSILE 347
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-344 4.25e-118

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 344.88  E-value: 4.25e-118
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923   1 MNPIVTIIIFTTLIMGTLIAMISSHWLMTWIGLEMNMFAIIPLIMKSHSPRTTEAATKYFLIQASASMMLLLAASLNFME 80
Cdd:MTH00112    1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923  81 TGQWTLTSLESSLSSTILLISLMMKLGMAPFHFWVPEVTQGTKLSTGLIILTWQKLAPLSIMYQIHPSLNPNIMLTSAVL 160
Cdd:MTH00112   81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 161 SILVGGWGGLNQTQLRKIMAYSSIAHMGWMAAVVVFNPSLMLLNLLLYIIFTLAMFTILMNCHSTSTSTLSMTWNNYPLM 240
Cdd:MTH00112  161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 241 TTMMLTVLMSMGGLPPLSGFIPKWLIMDELIKNNNIMLSTTMAVMALLNLYFYMRLIYASSLTLFPSNNNIKFKWKINTP 320
Cdd:MTH00112  241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                         330       340
                  ....*....|....*....|....
gi 1018446923 321 HKIaLLPTMLTLSTLILPLTPMIY 344
Cdd:MTH00112  321 KNT-LTATLTTLSTLLLPLSPMIL 343
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-343 5.42e-118

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 344.87  E-value: 5.42e-118
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923   1 MNPIVTIIIFTTLIMGTLIAMISSHWLMTWIGLEMNMFAIIPLIMKSHSPRTTEAATKYFLIQASASMMLLLAASLNFME 80
Cdd:MTH00135    1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923  81 TGQWTLTSLESSLSSTILLISLMMKLGMAPFHFWVPEVTQGTKLSTGLIILTWQKLAPLSIMYQIHPSlNPNIMLTSAVL 160
Cdd:MTH00135   81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPT-NPTLLITLGLT 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 161 SILVGGWGGLNQTQLRKIMAYSSIAHMGWMAAVVVFNPSLMLLNLLLYIIFTLAMFTILMNCHSTSTSTLSMTWNNYPLM 240
Cdd:MTH00135  160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPAL 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 241 TTMMLTVLMSMGGLPPLSGFIPKWLIMDELIKNNNIMLSTTMAVMALLNLYFYMRLIYASSLTLFPSNNNIKFKWKINTP 320
Cdd:MTH00135  240 TALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPST 319

                         330       340
                  ....*....|....*....|...
gi 1018446923 321 HKIALLPTMLTLSTLILPLTPMI 343
Cdd:MTH00135  320 QLTLPLAISTTATLMLLPLTPAI 342
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-346 2.08e-113

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 333.04  E-value: 2.08e-113
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923   1 MNPIVTIIIFTTLIMGTLIAMISSHWLMTWIGLEMNMFAIIPLIMKSHSPRTTEAATKYFLIQASASMMLLLAASLNFME 80
Cdd:MTH00070    1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923  81 TGQWTLTSLESSLSSTILLISLMMKLGMAPFHFWVPEVTQGTKLSTGLIILTWQKLAPLSIMYQIHPSLNPNIMLTSAVL 160
Cdd:MTH00070   81 TGEWTIMNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMGLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 161 SILVGGWGGLNQTQLRKIMAYSSIAHMGWMAAVVVFNPSLMLLNLLLYIIFTLAMFTILMNCHSTSTSTLSMTWNNYPLM 240
Cdd:MTH00070  161 STLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 241 TTMMLTVLMSMGGLPPLSGFIPKWLIMDELIKNNNIMLSTTMAVMALLNLYFYMRLIYASSLTLFPSNNNIKFKWKINTp 320
Cdd:MTH00070  241 TSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRFKN- 319

                         330       340
                  ....*....|....*....|....*.
gi 1018446923 321 HKIALLPTMLTLSTLILPLTPMIYIL 346
Cdd:MTH00070  320 KTNNLLSLTIILSLMLLPITPTILNL 345
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 1-340 8.92e-85

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 260.25  E-value: 8.92e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923   1 MNPIVTIIIFTTLIMGTLIAMISSHWLMTWIGLEMNMFAIIPLIMKSHSPRTTEAATKYFLIQASASMMLLLAASLNFME 80
Cdd:MTH00041    1 MNRNVLIFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923  81 TGQWTLTSLESSLSSTILLISLMMKLGMAPFHFWVPEVTQGTKLSTGLIILTWQKLAPLSIMYQIHPSLNPNIMLTSAVL 160
Cdd:MTH00041   81 SGSWSINGPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 161 SILVGGWGGLNQTQLRKIMAYSSIAHMGWMAAVVVFNPSLMLLNLLLYIIFTLAMFTILMNCHSTSTSTLSMTWNNYPLM 240
Cdd:MTH00041  161 SVLVGGWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPIS 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 241 TTMMLTVLMSMGGLPPLSGFIPKWLIMDELIKNNNIMLSTTMAVMALLNLYFYMRLIYASSLTLFPSNNNIKFKWKINTP 320
Cdd:MTH00041  241 AFLFILSILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHSISLFSWRNSGN 320

                         330       340
                  ....*....|....*....|....*
gi 1018446923 321 -----HKIALLPTMLTLSTLILPLT 340
Cdd:MTH00041  321 itvygVILSILSSISILGLLLIPLF 345
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-346 1.93e-83

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 256.82  E-value: 1.93e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923   1 MNPIVTIIIFTTLIMGTLIAMISSHWLMTWIGLEMNMFAIIPLIMKSHSPRTTEAATKYFLIQASASMMLLLAASLNFME 80
Cdd:MTH00200    1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923  81 TGQWTLTSLESSLSSTILLISLMMKLGMAPFHFWVPEVTQGTKLSTGLIILTWQKLAPLSIMYQIHPSLNPNIMLTSAVL 160
Cdd:MTH00200   81 SGQWGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 161 SILVGGWGGLNQTQLRKIMAYSSIAHMGWMAAVVVFNPSLMLLNLLLYIIFTLAMFTILMNCHSTSTSTLSMTWNNYPLM 240
Cdd:MTH00200  161 SVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPIL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 241 TTMMLTVLMSMGGLPPLSGFIPKWLIMDELIKNNNIMLSTTMAVMALLNLYFYMRLIYASSLTLFPSNNNIKFKWKiNTP 320
Cdd:MTH00200  241 SMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWR-TKS 319

                         330       340
                  ....*....|....*....|....*.
gi 1018446923 321 HKIALLPTMLTLSTLILPLTPMIYIL 346
Cdd:MTH00200  320 NSNLLVGLLLLLSILGLPLTPQLLFL 345
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-346 1.37e-52

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 176.55  E-value: 1.37e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923   1 MNPIVTIIIFTTLIMGTLIAMISSHWLMTWIGLEMNMFAIIPLIMKSHSPRTTEAATKYFLIQASASMMLLLAASLNFMe 80
Cdd:MTH00160    2 MMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML- 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923  81 tgqwtLTSLESSLSSTILLISLMMKLGMAPFHFWVPEVTQGTKLSTGLIILTWQKLAPLSIMYQIhpsLNPNIMLTSAVL 160
Cdd:MTH00160   81 -----NLMLFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYL---INNNFIIIIIIL 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 161 SILVGGWGGLNQTQLRKIMAYSSIAHMGWMAAVVVFNPSLMLLNLLLYIIFTLAMFTILMNCHSTSTSTLSMTWNNYPLM 240
Cdd:MTH00160  153 SAIIGAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKI 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 241 TTMMLTVLMSMGGLPPLSGFIPKWLIMDELIKNNNIMLSTTMAVMALLNLYFYMRLIYASsltLFPSNNNIKFKWKINTP 320
Cdd:MTH00160  233 KFLLFLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSS---LMLNYNKNKWNLKKKKN 309

                         330       340
                  ....*....|....*....|....*.
gi 1018446923 321 HKIALLPTMLTLSTLILPLTPMIYIL 346
Cdd:MTH00160  310 KFSLILNFLSFISLFGLILSSLLFLL 335
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 10-338 4.80e-50

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 169.96  E-value: 4.80e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923  10 FTTLIMGTLIAMISSHWLMTWIGLEMNMFAIIPLIMKSHSPRTTEAATKYFLIQASASMMLLLAASLnfmetgQWTLTSL 89
Cdd:MTH00011   12 SSTMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTM------MWSFPSL 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923  90 ESSLSSTILLISLMMKLGMAPFHFWVPEVTQGTKLSTGLIILTWQKLAPLSIMYQIHPSLNPNIMLTSAVLSILVGGWGG 169
Cdd:MTH00011   86 LKNITALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAMSALAGGLGG 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 170 LNQTQLRKIMAYSSIAHMGWMAAVVVFNPSLMLLNLLLYIIFTLAMFTILMNCHSTSTSTLSMTWNNYPLMTTMMLTVLM 249
Cdd:MTH00011  166 MNQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLFIMLL 245

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 250 SMGGLPPLSGFIPKWLIMDELIKNNNIMLSTTMAVMALLNLYFYMRLIYASsltlFPSNNNIKFKWKINTPHKIALLPTM 329
Cdd:MTH00011  246 SLGGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFNF----MYLSPTFSSLKSAPYEPKTKILISM 321


                  ....*....
gi 1018446923 330 LTLSTLILP 338
Cdd:MTH00011  322 CTLSLGLIP 330
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 10-315 6.30e-49

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 166.99  E-value: 6.30e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923  10 FTTLIMGTLIAMISSHWLMTWIGLEMNMFAIIPLIMKSHSPRTTEAATKYFLIQASASMMLLLAASLNFMETGQWTLTSL 89
Cdd:MTH00144   10 LFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSWFSMSL 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923  90 ESSLSstillislMMKLGMAPFHFWVPEVTQGTKLSTGLIILTWQKLAPLSIMYQIHPSLNP-NIMLTSAVLSILVGGWG 168
Cdd:MTH00144   90 LLLGL--------CLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWLaYLLCVISVLSALVGSIG 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 169 GLNQTQLRKIMAYSSIAHMGWMAAVVVFNPSLMLLNLLLYIIFTLAMFTILMNCHSTSTSTLSMTWNNYPLMTTMMLtVL 248
Cdd:MTH00144  162 GLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDLGSLKPSYKTGLSIIS-LL 240

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1018446923 249 MSMGGLPPLSGFIPKWLIMDELIKNNNIMLSTTMAVMALLNLYFYMRLIYASSLTLFPSNNNIKFKW 315
Cdd:MTH00144  241 LSLGGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSNSSKV 307
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 12-340 2.21e-40

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 144.43  E-value: 2.21e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923  12 TLIMGTLIAMISSHWLMTWIGLEMNMFAIIPLIMKSHSPRTTEAATKYFLIQASASMMLLLAASLNFMEtgqwtltSLES 91
Cdd:MTH00197    6 IIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSLSFSN-------LYLS 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923  92 SLSSTILLISLMMKLGMAPFHFWVPEVTQGTKLSTGLIILTWQKLAPLSIMYQIhpSLNPNIMLTSAVLSILVGGWGGLN 171
Cdd:MTH00197   79 LLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFN--SSSFMGLLICSVLSSLIGGIGGMN 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 172 QTQLRKIMAYSSIAHMGWMAAVVVFNPSLMLLNLLLYIIFTLAMFTILMNCHSTSTSTLSMTWNNYPLMTTMMLTVLMSM 251
Cdd:MTH00197  157 QSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLSFLSL 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 252 GGLPPLSGFIPKWLIMDELIKNNNIMLSTTMAVMALLNLYFYMRLIYASsltLFPSNNNIKFKWKINTPHKIALLPTMLT 331
Cdd:MTH00197  237 GGLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKS---LILSNWMINFLMKINLLYSGLFILLMMM 313


                  ....*....
gi 1018446923 332 LSTLILPLT 340
Cdd:MTH00197  314 LPLLMIFTM 322
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 6-299 6.27e-29

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 116.37  E-value: 6.27e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923   6 TIIIFTTLIMGTLIAmiSSHWLMTWIGLEMNMFAIIPLI-MKSHSPRTTEAATKYFLIQASASMMLLLAASLNFMETGQW 84
Cdd:COG1007   106 ALLLFATLGMMLMAS--ANDLLTLFLGLELLSLSLYVLVaFRRDDRRSSEAALKYFLLGALSSGFLLYGISLLYGATGSL 183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923  85 TLTSLESSLSSTILLISLMM------------KLGMAPFHFWVPEVTQGTKLSTGLIILTWQKLAPLS----IMYQIHPS 148
Cdd:COG1007   184 NLAGIAAALAAGGANSPLLLlglvlvlaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAallrLLVEAFPG 263

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 149 LNP---NIMLTSAVLSILVGGWGGLNQTQLRKIMAYSSIAHMGWM-AAVVVFNP---SLMLLNLLLYIIFTLAMFTILMn 221
Cdd:COG1007   264 LAAdwqLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLlLGLAAGTPlgvSAALFYLLAYLFMNLGAFAVIL- 342

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 222 cHSTSTSTLSMTWNNY-------PLMTTMMLTVLMSMGGLPPLSGFIPKWLIMDELIKNNNIMLSTTMAVMALLNLYFYM 294
Cdd:COG1007   343 -LLSRKGGEAEEIEDLaglarrsPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYL 421


                  ....*
gi 1018446923 295 RLIYA 299
Cdd:COG1007   422 RVVKA 426
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 6-298 2.06e-26

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 108.95  E-value: 2.06e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923   6 TIIIFTTLIMGTLIAMISSHWLMTWIGLEMNMFAI-IPLIMKSHSPRTTEAATKYFLIQASASMMLLLAASLNFMETG-- 82
Cdd:MTH00199   99 SPILILIVALGSLLLVSSINWLSIYLAIELQTLTLfILVALKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGet 178

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923  83 --QWTLTSLESSLSSTILLISLMMKLGMAPFHFWVPEVTQGTKLSTGLIILTWQKLAPLSIMYQIHPSLNpnIMLTSAVL 160
Cdd:MTH00199  179 siQGINSILTGDVGKILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTN--VVLICAVL 256

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 161 SILVGGWGGLNQTQLRKIMAYSSIAHMG---WMAAVVVFNP-SLMLLNLLLYIIFTLAMFTIL--MNCHSTSTSTLSMTW 234
Cdd:MTH00199  257 SIIYGAIGALNQTKIKRLLAYSGIGHMGfilFGVAIGSFESiQASLIYMIIYVIMSICSFSIIlsLKLTKGLIVEVSGLS 336

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1018446923 235 NNYPLMTTMMLTVLMSMGGLPPLSGFIPKWLIMDELIKNNNIMLSTTMAVMALLNLYFYMRLIY 298
Cdd:MTH00199  337 RKNPVIALTLALTFLSIAGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRVVQ 400
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 13-318 2.72e-24

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 101.65  E-value: 2.72e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923  13 LIMGTLIAMISSHWLMTWIGLEMNMFAIIPLI-MKSHSPRTTEAATKYFLIQASASMMLLLAASL-------------NF 78
Cdd:MTH00196    2 VALGILCLISSSNWLSVYLAIELQTLSLFILIaQNRGSGYSAEAGLKYFVLGALSSGLFLFGCALlcgttgglhlsyiNL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923  79 METGQWTLTSLESSLSSTILLISLMMKLGMAPFHFWVPEVTQGTKLSTGLIILTWQKLAPLSIMYQIHPslNPNIMLTSA 158
Cdd:MTH00196   82 VLNSGQSFSSVSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGL--NVNILLIGG 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 159 VLSILVGGWGGLNQTQLRKIMAYSSIAHMGWMAAVVVFNP----SLMLLNLLLYIIFTLAMFTILM--NCHSTSTSTLSM 232
Cdd:MTH00196  160 LFSLFVGAIGALNQTKIKRLLAYSGIGHMGFVLWGIEIGSfesiQASLVYLFIYIIMSICVFSIILalNVYKNLIIEFSG 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 233 TWNNYPLMTTMMLTVLMSMGGLPPLSGFIPKWLIMDELIKNNNIMLSTTMAVMALLNLYFYMRLI----YASSLTLFPSN 308
Cdd:MTH00196  240 LSRRLPILAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRIVkilfFQANSFLLIST 319

                         330
                  ....*....|
gi 1018446923 309 NNIKFKWKIN 318
Cdd:MTH00196  320 KILKKENKIN 329
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
6-297 7.62e-24

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 101.82  E-value: 7.62e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923   6 TIIIFTTLIMgtlIAMISS-HWLMTWIGLEMNMFAIIPLI-MKSHSPRTTEAATKYFLIQASASMMLLLAASLNFMETGQ 83
Cdd:PRK05777  107 LLVLFALLGM---MVMVSAnDLLTLFLGLELLSLPLYALAaLRRDRRRSLEAAIKYFVLGALASGFLLYGMSLLYGATGS 183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923  84 WTLTSLESSLSSTILLISLMM------------KLGMAPFHFWVPEVTQGTKLSTGLIILTWQKLAP----LSIMYQIHP 147
Cdd:PRK05777  184 LSFAGIAKALADGSGNSLLLLfglvfllvglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAfavlLRLLVVAFG 263

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 148 SLNP---NIMLTSAVLSILVGGWGGLNQTQLRKIMAYSSIAHMGWM----AAVVVFNPSLMLLNLLLYIIFTLAMFT-IL 219
Cdd:PRK05777  264 GLSEdwqQVLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLlvglAAGTAEGYSAVLFYLLAYLFMTLGAFGvIS 343

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 220 MNCHSTSTSTLSMTWN----NYPLMTTMMLTVLMSMGGLPPLSGFIPKWLIMDELIKNNNIMLSTTMAVMALLNLYFYMR 295
Cdd:PRK05777  344 LLRRKGGEAESISDFAglskRSPLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFYYLR 423


                  ..
gi 1018446923 296 LI 297
Cdd:PRK05777  424 VI 425
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 4-297 9.74e-23

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 98.48  E-value: 9.74e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923   4 IVTIIIFTTLimGTLIAMISSHWLMTWIGLEMNMFAIIPLI-MKSHSPRTTEAATKYFLIQASASMMLLLAASLNFMETG 82
Cdd:TIGR01770 104 FYILLLFALL--GIFLLVSSNDLLSIYLGLELQSLCFYVLAgLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTG 181

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923  83 QWTLTSLESSLSSTILLISL------------MMKLGMAPFHFWVPEVTQGTKLSTGLIILTWQKLAPLSIMYQIHPSL- 149
Cdd:TIGR01770 182 SLNFEDLLLFLSNGMLNISLlllgivlilvglLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYIl 261

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 150 ------NPNIMLTSAVLSILVGGWGGLNQTQLRKIMAYSSIAHMGWMAAVVVFNP----SLMLLNLLLYIIFTLAMFTIL 219
Cdd:TIGR01770 262 fgfseaWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTlegiKAVLFYIFIYALMSLGAFGVL 341

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 220 MNchstsTSTLSMTWNNY-----------PLMTTMMLTVLMSMGGLPPLSGFIPKWLIMDELIKNNNIMLSTTMAVMALL 288
Cdd:TIGR01770 342 SL-----LRSYKDEWIEYisdfaglfktnPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVI 416


                  ....*....
gi 1018446923 289 NLYFYMRLI 297
Cdd:TIGR01770 417 GAFYYLRVV 425
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-267 7.75e-21

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 90.84  E-value: 7.75e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923  23 SSHWLMTWIGLEMNMFAIIPLI-MKSHSPRTTEAATKYFLIQASASMMLLLAASLNFMETGQWTLTSLESSLSSTILLIS 101
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKALTGGLNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 102 LMM-----------KLGMAPFHFWVPEVTQGTKLSTGLIIL-TWQKLAPLSIM---YQIHPSLN--PNIMLTSAVLSILV 164
Cdd:pfam00361  81 LLLlfllilvgflfKSAQVPFHTWLPDAYEGAPTPVSALLAaTLVKAGGYGLIrrsLLYLPSSPfiQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 165 GGWGGLNQTQLRKIMAYSSIAHMGWM----AAVVVFNPSLMLLNLLLYIIFTLAMF-----TILMNCHSTSTSTLSMTWN 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMlialGAGTIYGIQAAIFHLLTHGLFSAGLFlcagsVIYRRVHTRNIRDYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|..
gi 1018446923 236 NYPLMTTMMLTVLMSMGGLPPLSGFIPKWLIM 267
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLIL 272
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 10-301 5.58e-19

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 87.12  E-value: 5.58e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923  10 FTTLIMGTLIAMISSHWLMTWIGLEMNMFAIIPLIMKSHSPRTTEAATKYFLIQASASMMLLLAASLNFMETGQWTLTSL 89
Cdd:COG0651   113 FLLLLAGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNMADL 192

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923  90 ESSLSSTILLISL----------MMKLGMAPFHFWVPE-----------VTQGTKLSTGL--IILTWQKLAPLSIMYQIH 146
Cdd:COG0651   193 AARLAELDPGLLLaafalllvgfGIKAALFPLHFWLPDaypaapspvsaLLSGLLTKVGVyaILRVLTLLFGADPALFLG 272

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 147 PslnpnIMLTSAVLSILVGGWGGLNQTQLRKIMAYSSIAHMGWMAAVVVFNPSLMLLNLLLYII----FTLAMF----TI 218
Cdd:COG0651   273 T-----LLLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHLLnhalAKALLFlaagAI 347

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 219 LMNCHSTSTSTLSMTWNNYPLMTTMMLTVLMSMGGLPPLSGFIPKWLIMDELIKNNNIMLSTTMAVMALLNLYFYMRLIY 298
Cdd:COG0651   348 ERATGTRDLDKLGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAYFVRIFG 427


                  ...
gi 1018446923 299 ASS 301
Cdd:COG0651   428 RAQ 430
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 15-291 5.31e-14

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 72.97  E-value: 5.31e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923  15 MGTLIAMISSHWLMTWIGLEMNMFAIIPLIMKSHSPRTT---------EAATKYFLIQASASMMLLLAASLNFMETGQWT 85
Cdd:MTH00198  199 LGGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFGCALYFGFTGNEG 278

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923  86 LTSLESSLSS--------------TILLISLMMKLGMAPFHFWVPEVTQGTKLSTGLIILTWQKLAPLSIMYQIhpSLNP 151
Cdd:MTH00198  279 MLGTILSATLettnielrqgslgyLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILLTSL--VITS 356

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 152 NIMLTSAVLSILVGGWGGLNQTQLRKIMAYSSIAHMGWM----AAVVVFNPSLMLLNLLLYIIFTLAMFTILMNCHSTST 227
Cdd:MTH00198  357 KLLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFIligvSAGTYESLQASWTYAVTYLVSALASFTVICTLEEFGT 436

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 228 STLSM-----TWNNY----------------PLMTTMMLTVLMSMGGLPPLSGFIPKWLIMDELIKnnnIMLSTTMAVMA 286
Cdd:MTH00198  437 RTPTSrqrdgSFGNYnlvrrlvdltilsrgqPYIAFSLAIVFLSLAGIPPLLGFLGKWFILVGSIK---IAFSSSLSIYY 513


                  ....*
gi 1018446923 287 LLNLY 291
Cdd:MTH00198  514 LVALF 518
NADH_dehy_S2_C pfam06444
NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region ...
 291-341 2.33e-10

NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region specific to the eukaryotic NADH dehydrogenase subunit 2 protein and is found in conjunction with pfam00361.


Pssm-ID: 461914 [Multi-domain]  Cd Length: 51  Bit Score: 55.34  E-value: 2.33e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1018446923 291 YFYMRLIYASSLTLFPSNNNIKFKWKINTPHKIALLPTMLTLSTLILPLTP 341
Cdd:pfam06444   1 FFYLRLSYSTTLTLFPNTNNSKMKWRFNSTKNTLLLPTLTTLSILLLPLTP 51
PRK12662 PRK12662
putative monovalent cation/H+ antiporter subunit D; Reviewed
 152-342 5.20e-07

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 183662 [Multi-domain]  Cd Length: 492  Bit Score: 51.27  E-value: 5.20e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 152 NIMLTSAVLSILVGGWGGLNQTQLRKIMAYSSIAHMGWMAAVVVFNPSLMLLNLLLYII--------FTLAMFTILMNCH 223
Cdd:PRK12662  280 NVFMILAALAIVFGSVLAILSKDIKRIFAYSSISHIGYIILAVSLNTYYGLAAAVAYIVnhsivksaLFMVSGSISYHFG 359

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 224 STSTSTLSMTWNNYPLMTTMMLTVLMSMGGLPPLSGFIPKWLIMDELIKNNNIMLSTTMAVMALLNLYFYMRLI---YAS 300
Cdd:PRK12662  360 TTKLEDCLNLWKSMPKITLAFVLLSLSLIGMPPTSGFVAKWYILDAFIKSNAWIGLVVLLVGSGLSVIYVWKIVealYFE 439

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 1018446923 301 SLTLFPSNNNIKFKwkinTPHKIALLPTMLTLSTLILPLTPM 342
Cdd:PRK12662  440 SRMVESKANDKAFK----TPNAMVLCIWIMAILSIIVGIYPI 477
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
10-297 7.80e-07

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 50.43  E-value: 7.80e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923  10 FTTLIMGTLIAMI---SSHWLMTWIGLEMnmFAIIPLIMKSH---SPRTTEAATKYFLIQASASMMLLLAASLNF-METG 82
Cdd:PRK02504  113 AAILLTATLGGMFlsgATELVMIFISLET--LSIASYLLTGYmkrDPRSNEAALKYLLIGAASSAIFLYGSSLLYgLSGG 190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923  83 QWTLTSLESSLSSTILLISLM----------MKLGMAPFHFWVPEVTQGTK------LSTGliiltwQKLA----PLSIM 142
Cdd:PRK02504  191 STQLSAIALALITSPSLGLALalvfviagiaFKISAVPFHQWTPDVYEGSPtpvvafLSVG------SKAAgfalAIRLL 264

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 143 YQIHPSLNPN---IMLTSAVLSILVGGWGGLNQTQLRKIMAYSSIAHMGWMAAVVVFNPSLMLLNLLLYIIFTLAM---- 215
Cdd:PRK02504  265 VTAFPSFDEQwklLFTALAILSMVLGNVVALAQTSMKRMLAYSSIGQAGFVMIGLVAGTEAGYASMVFYLLAYLFMnlga 344

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 216 FT--ILMNCHSTS--TSTLSMTWNNYPLMTTMMLTVLMSMGGLPPLSGFIPKWLIMDELIKNNNIMLSTTMAVMALLNLY 291
Cdd:PRK02504  345 FAcvILFSLRTGTdqISDYAGLYQKDPLLTLGLSLCLLSLGGIPPLAGFFGKIYLFWAGWQAGLYLLVLVGLVTSVISIY 424


                  ....*.
gi 1018446923 292 FYMRLI 297
Cdd:PRK02504  425 YYIRVI 430
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 16-274 2.06e-06

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 49.22  E-value: 2.06e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923  16 GTLIAMISSHWLMTWIGLEMNMFA---IIPLIMKshspRTTEAATKYFLIQASASMMLLLAASLNFMETGQWTLTSLESS 92
Cdd:PRK08668  110 GVLGVFLANDLLTLYIFWEIMTFSsfmMVPMGKK----ESRKASLKYFVLSAIGAYAMLYAIFLIYAKTGTFDFADISQG 185

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923  93 LSSTILLISLMM-----------KLGMAPFHFWVPEVTQGTK------LSTGLI------------ILTWQKLAPLSIMY 143
Cdd:PRK08668  186 LINDTSTGFALIvflfllafgvaKAGIFPLHVWAPDAYSEAPqsfsavLSGQLSklgaygfllvlyVLPGTKLFSEFGTY 265

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 144 QIHPSLNPNIMLTSAvLSILVGGWGGLNQTQLRKIMAYSSIAHMGW-MAAVVVFNPslMLLNLLLYIIFTLAMFTILMNC 222
Cdd:PRK08668  266 RGVPLFNYILAWLGN-ISIIVGTLMAILQEDIKKLIAYSSVANGGYiLVGLGLGTS--LGFAGGLFHVFNHALFKGLFFL 342

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1018446923 223 HSTSTSTLSMTWN---------NYPLMTTMMLTVLMSMGGLPPLSGFIPKWLIMDELIKNN 274
Cdd:PRK08668  343 IFAAVIYRTGTTKisemgglieKMPFTFAMYLVAIISLAGIPPMSGFASKWLIFEALISKG 403
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 54-298 6.58e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 47.66  E-value: 6.58e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923  54 EAATKYFLIQASASMMLLLA--------ASLNF-------------METGQWTLTSLESSLSSTILLISLMMKLGMAPFH 112
Cdd:PRK12667  164 EAAIKYALIGAVGTTLYFLAlaflyatfGTLNMadlsakirglsfpLTGGLAGNPPLALGVALALALWAFTIKAAIFPNH 243

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 113 FWVPEV-----TQGTKLSTGLIILTwQKLAPLSIMYQIHPS----------LNPNIMLTSAVlSILVGGWGGLNQTQLRK 177
Cdd:PRK12667  244 FWLPDAhpaapSPVSAMLSGLVVNV-GAYAIIRFLYTIFGIspslidfraaLSPILIILGAV-SAIIGALMMVVQKDVKR 321

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 178 IMAYSSIAHMGWMAAVVVFNPSLMLLNLLLYII-FTLAMFTILMNCHSTSTST-------LSMTWNNYPLMTTMMLTVLM 249
Cdd:PRK12667  322 LLAYSTISHMGYIFMGIGIGTQLGLAAALFHIInHAIAKSLLFLASGVFIHAAgtrdideLAGLGRKMPIASFAFLIGAL 401

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 1018446923 250 SMGGLPPLSGFIPKWLIMDELIKNNNIMLSTTMAVMALLNLYFYMRLIY 298
Cdd:PRK12667  402 SLVGIPPLNGFFSKLLLFNALLESGFYLPALVLLIASAISLVGYFRAWY 450
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 105-299 8.33e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 47.18  E-value: 8.33e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 105 KLGMAPFHFWVPEV-TQGTKLSTGLIILTWQKLAPLSIM----------YQIHPSLNPNIMLTsAVLSILVGGWGGLNQT 173
Cdd:PRK08375  215 KAAVFPLHTWLPRAyPAAPPVVTALLSGLVTKVAVYALIriyftvfggdFRFALGLGWLLAVL-ALLSMLVGSLAALGQD 293

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 174 QLRKIMAYSSIAHMGWMAAVVVFNPSLMLLNLLLYI----IFTLAMF----TILMNCHSTSTSTLSMTWNNYPLMTTMML 245
Cdd:PRK08375  294 DVKRVLAYSTVSQMGYILLGLALLTPLALAAGLLHLlhhaLMKGALFlaagAIEVTYGTRRLSELSGLGRRMPLTAAAFA 373

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1018446923 246 TVLMSMGGLPPLSGFIPKWLIMDELIKNNNIMLSTTMAVMALLNLYFYMRLIYA 299
Cdd:PRK08375  374 VASLSLIGVPPTSGFVSKWYLVVGAVEAGQWLVLAVLLASSLLALLYFLRIWYR 427
PRK12663 PRK12663
Na+/H+ antiporter subunit D;
145-296 1.25e-05

Na+/H+ antiporter subunit D;


Pssm-ID: 237163 [Multi-domain]  Cd Length: 497  Bit Score: 46.87  E-value: 1.25e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 145 IHPSLNPNIMLTSAVLSILVGGWGGLNQTQLRKIMAYSSIAHMGWM-AAVVVFNPSLMLLNlllyiIFTLAMFTILMN-- 221
Cdd:PRK12663  266 QERELLHPLLATMAAITMVIGALGALAYKDIRRIAGYQVISSIGFIlLGLALGTPAGINGA-----IFYLVHDMVVKTal 340

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 222 ----------CHSTSTSTLSMTWNNYPLMTTMMLTVLMSMGGLPPLSGFIPKWLIMDELIKNNNIMLSTTMAVMALLNLY 291
Cdd:PRK12663  341 fliagslvrlTGYRSLQYLGGLYRKEPLFGALFLILIFAIGGLPPFSGFWGKVLLVQGALDNGAYILLALMLITSLITMY 420


                  ....*
gi 1018446923 292 FYMRL 296
Cdd:PRK12663  421 SLFRI 425
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 10-298 2.17e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 46.24  E-value: 2.17e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923  10 FTTLIM----GTLIAMISSHWLMTWIGLEMNMFAIIPLI-MKSHSPRTTEAATKYFLIQASASMMLLLAASLNFMETGQW 84
Cdd:PRK08376  123 YYTLILllelGMLGMAITGDLFNFFVFLEIMSIASYALVaFRNDTWEAIEAGIKYMFVGSLASSMVLLGIALLYGQYGTL 202

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923  85 TLTSLESSLSSTILLISLM----------MKLGMAPFHFWVPEVTQGTKLSTGLIILTwQKLAPLSIMYQI-----HPSL 149
Cdd:PRK08376  203 NMAYLAVKMSENPTVVAKIalalfiaglaMKSGAVPVHMWLPDAYPAAPSSISAMLLV-IKQAGLYALARVlfsiyGPAI 281

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 150 NPN----IMLTSAVLSILVGGWGGLNQTQLRKIMAYSSIAHMGWM-----AAVVVFNPSLMLLNLLL------YIIFTLA 214
Cdd:PRK08376  282 NLAtvgwVIIILGCLTMFVGVAMAVVQKDVKRLLAYHSVSQIGYMllglgVGLAALGDPAMASYGEIalaggiYHIVNHA 361

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 215 MFTILMNCHSTSTSTLSMTWN---------NYPLMTTMMLTVLMSMGGLPPLSGFIPKWLIMDELIKNNNIMLSTTMaVM 285
Cdd:PRK08376  362 LYKALLFLTAGAVIYETGTRNlnelgglarTMPKTTIAFLIGAAAIVGLPPFNGFASKWLIYESSALFNPILGVIAM-IG 440

                         330
                  ....*....|...
gi 1018446923 286 ALLNLYFYMRLIY 298
Cdd:PRK08376  441 SVLTLASFVKVFH 453
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 153-267 2.17e-05

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 45.84  E-value: 2.17e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 153 IMLTSAVLSILVGGWGGLNQTQLRKIMAYSSIAHMGWM-AAVVVFNPSLMLLNLLLYI---IFTLAMF----TILMNCHS 224
Cdd:COG1008   277 LLAALGVIGIIYGALVALAQTDLKRLIAYSSVSHMGFVlLGIFALNPLGLQGAVLQMVshgLITAALFllvgVLYDRTHT 356

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1018446923 225 TSTSTLSMTWNNYPLMTTMMLTVLMSMGGLPPLSGFIPKWLIM 267
Cdd:COG1008   357 RDIADLGGLAKRMPVLAALFLLAALASLGLPGTSGFVGEFLVL 399
ndhB CHL00049
NADH dehydrogenase subunit 2
 105-297 7.06e-05

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 44.61  E-value: 7.06e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 105 KLGMAPFHFWVPEVTQGTKLSTGLIILTWQKLAPLS----IMYQIHPSLNP---NIMLTSAVLSILVGGWGGLNQTQLRK 177
Cdd:CHL00049  227 KLSLAPFHQWTPDVYEGSPTPVVAFLSVTSKVAASAlatrIFDIPFYFSSNewhLLLEILAILSMILGNLIAITQTSMKR 306

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 178 IMAYSSIAHMGW-MAAVVVFNPSLMLLNLLLYIIFTLAMFTILMNCHSTSTSTLSM--------TWNNYPLMTTMMLTVL 248
Cdd:CHL00049  307 MLAYSSIGQIGYvIIGIIVGDSNDGYASMITYMLFYIFMNLGTFACIVLFGLRTGTdnirdyagLYTKDPFLALSLALCL 386

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1018446923 249 MSMGGLPPLSGFIPKWLIMDELIKNNNIMLSTTMAVMALLNLYFYMRLI 297
Cdd:CHL00049  387 LSLGGIPPLAGFFGKLYLFWCGWQAGLYFLVSIGLLTSVISIYYYLKII 435
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 105-267 1.11e-04

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 43.77  E-value: 1.11e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 105 KLGMAPFHFWVPEV-TQGTKLSTGLIILTWQKLAPLSIMYQIHPsLNPN-------IMLTSAVLSILVGGWGGLNQTQLR 176
Cdd:TIGR01972 216 KVPLFPLHTWLPDAhVEAPTAGSVILAGVLLKMGTYGFLRFNLP-LFPDaslyfapVLAALGVIAIIYGALIALAQTDIK 294

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 177 KIMAYSSIAHMGWMA-AVVVFNPSLMLLNLLLYI---IFTLAMF----TILMNCHSTSTSTLSMTWNNYPLMTTMMLTVL 248
Cdd:TIGR01972 295 RLIAYSSISHMGFVLlGIFSFNELGISGAVFQMIshgLITAALFllvgVLYERAHTRDIAKYGGLANKMPVLAAFFMLFA 374

                         170
                  ....*....|....*....
gi 1018446923 249 MSMGGLPPLSGFIPKWLIM 267
Cdd:TIGR01972 375 MASLGLPGTSGFVGEFLIL 393
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 153-298 1.11e-03

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 40.91  E-value: 1.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 153 IMLTSAVLSILVGGWGGLNQTQLRKIMAYSSIAHMGWMAAVVVFNpslmLLNLLLYIIFTLAMF---------TILMNCH 223
Cdd:COG1009   277 VVAIIGAITALFAALIALAQTDIKRVLAYSTVSQLGYMFLALGVG----AYVAALFHLLTHAFFkallflgagSVIHATG 352

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1018446923 224 STSTSTLSMTWNNYPLMTTMMLTVLMSMGGLPPLSGFIPKWLIMDELIKNN--NIMLSTTMAVMALLNLYFYMRLIY 298
Cdd:COG1009   353 TRDIRKMGGLRKKMPITAITFLIGALSLAGIPPFAGFFSKEAILEAALEAGglGPLLLAVALLGAFLTAFYSFRLFF 429
ND2 MTH00091
NADH dehydrogenase subunit 2; Provisional
 103-315 1.18e-03

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177154  Cd Length: 273  Bit Score: 40.24  E-value: 1.18e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 103 MMKLGMAPFHFWVPEVTQGTKLSTGLIILTWQKLAPLSIMYQIHPSLNPNIMLTSAVLSILVggwgGLNQTQLRKIMAYS 182
Cdd:MTH00091   68 MMKIGVAPFHFWIFSVTNGLFGWNLMWFLTFQKLPFLLVLLQFFSKNFFFLLLFGLLICFFQ----MFLLKSYKNLLILS 143

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 183 SIAHMGWMAAVVVFNpslMLLNLLLYIIFTLAMFTILMNCHSTststlsmtwNNYPLMTTMMLTVLMSmggLPPLSGFIP 262
Cdd:MTH00091  144 STESFNWLILSFFFS---FFNVFFLFFYYFLLMLFLIPKFNNV---------NKLNFVSWETLLVFMN---LPFSVTFFV 208

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1018446923 263 KWLIMDELIKNNNIMLSTTMAVMALLNLYFYMRLIYASSLTLFPSNNNIKFKW 315
Cdd:MTH00091  209 KIFSLSEILKVLGFFLLFLLFLMFLSVLSLSFWLVNLSTKLFLMLFKYNKGFF 261
PRK06589 PRK06589
putative monovalent cation/H+ antiporter subunit D; Reviewed
 12-337 7.78e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235835 [Multi-domain]  Cd Length: 489  Bit Score: 37.87  E-value: 7.78e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923  12 TLIMGTLIAMiSSHWLMTWIGLEMNMFAIIPLIMKSHSPRTTEAATKYFLIQASASMMLLL-AASLNFMETGQWTLTSLE 90
Cdd:PRK06589  125 TILIGVLIAL-SSDLFTMFVCYELLTISTAFLIGHTRNNISLSGGYKYLKILMISALLLFLpAVILIYTKTGNLDFVSGG 203

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923  91 SSLSSTILLISLMMKLGMA-----PFHFWVPEVTQGTK-----------LSTGLIILTWQKLAPLSIMYQIHPSLNPNIM 154
Cdd:PRK06589  204 LFSKNQSIILLLMFIYGIAktaifPVHSWLPAAMVAHYpvsallhavivVKTGLFCIYKILLYIFGLSYLQRIFAEFNWL 283

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 155 LTSAVLSILVGGWGGLNQTQLRKIMAYSSIAHMGW--MAAVVVFNPSLMLLNLLLY------IIFTLAMFTILMNCHSTS 226
Cdd:PRK06589  284 IFIPIVSIFYSSLKALKTDNIKKILAYSTISQLSLalLSAFILTPKALGAAILHLVshsfakICLFYSMGSIYSLKKEDQ 363

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1018446923 227 TSTLSMTWNNYPLMTTMMLTVLMSMGGLPPLSGFIPKWLIMDELIKNNNIMLSTTMA----VMALLNLYFYMRLIYASSL 302
Cdd:PRK06589  364 VDKLHGTSKSFPLISFIISISSLSLIGIPIFSGFISKFLILLAASEQNQPWLSIIVMlvviASSILSALYLLKILSSIYK 443

                         330       340       350
                  ....*....|....*....|....*....|....*
gi 1018446923 303 TLFPSNNNIKfkwkiNTPHKIALLPTMLTLSTLIL 337
Cdd:PRK06589  444 PSLSENSFIT-----KSLPYLMQISVITCCCALTL 473
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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