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Conserved domains on  [gi|1031914857|gb|ANG55681|]
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glucocorticoid receptor, partial [Onychognathus tenuirostris]

Protein Classification

glucocorticoid receptor( domain architecture ID 10490010)

glucocorticoid receptor (GR) is a ligand-activated transcription factor belonging to the nuclear receptor superfamily; it binds with high affinity to cortisol and other glucocorticoids. GR is expressed in almost every cell in the body and regulates genes controlling a wide variety of processes including the development, metabolism, and immune response of the organism

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GCR pfam02155
Glucocorticoid receptor;
1-321 1.64e-174

Glucocorticoid receptor;


:

Pssm-ID: 426625  Cd Length: 377  Bit Score: 488.23  E-value: 1.64e-174
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031914857   1 GGATVQAPVSTSPLPASSQSQSSQQPALADFPKGLGNNVPQPDLSKAVSLSMGLYMGETDAKVMGNDLGFSHQGQIGIPS 80
Cdd:pfam02155  10 GGARIKSTASSAPLAVVSQSDSKQQPVLGDFSKGLSNNATQPDLSKAVSLSMGLYMGETDTKVMGNDLGFPQQGQISFSS 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031914857  81 GETDFRLLEESIASLNKSSSLAEDAKGATSSAA------PDFPGMAGRGGPAEPGAAVQSQVGSNGGNVKLFSEDQSTLD 154
Cdd:pfam02155  90 GETDFRLLEESIASLNKSSSVPESLKGGVSPNLfplkteKDFPGMAKCDLSLEQDTFAQGQKGTNGGNLKLFSEDQSTFD 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031914857 155 ILQDLELPPVSPGKEPNGSPWRLDPLLDDGGLLSPISADDAFLLEGSLGEDCKPPLLSDTKPKINDRGDLL--PSSKMPM 232
Cdd:pfam02155 170 ILQDLELPPVSPGKETNGSPWRLDPLLDEGGLLSPLGADDPFLLEGNANEDCKPLILPDTKPKINETGDLLlsSASTSQL 249

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031914857 233 PQVKTEKEDYIELHTPGSIKQENTSPLYCQANFSSSNLLGTKVSAISIHGVSTSGGQMYHYDLNTASLSQQQDQKPIFNI 312
Cdd:pfam02155 250 PQVKTEKEDFIELCTPGVIKQEKLGTVYCQAGFPGANILGNKVSAISIHGVSTSGGQMYHYDLNTASVSQQQDQKPIFNM 329


                  ....*....
gi 1031914857 313 IPSLPAGSE 321
Cdd:pfam02155 330 IPPLPSGSE 338
 
Name Accession Description Interval E-value
GCR pfam02155
Glucocorticoid receptor;
1-321 1.64e-174

Glucocorticoid receptor;


Pssm-ID: 426625  Cd Length: 377  Bit Score: 488.23  E-value: 1.64e-174
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031914857   1 GGATVQAPVSTSPLPASSQSQSSQQPALADFPKGLGNNVPQPDLSKAVSLSMGLYMGETDAKVMGNDLGFSHQGQIGIPS 80
Cdd:pfam02155  10 GGARIKSTASSAPLAVVSQSDSKQQPVLGDFSKGLSNNATQPDLSKAVSLSMGLYMGETDTKVMGNDLGFPQQGQISFSS 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031914857  81 GETDFRLLEESIASLNKSSSLAEDAKGATSSAA------PDFPGMAGRGGPAEPGAAVQSQVGSNGGNVKLFSEDQSTLD 154
Cdd:pfam02155  90 GETDFRLLEESIASLNKSSSVPESLKGGVSPNLfplkteKDFPGMAKCDLSLEQDTFAQGQKGTNGGNLKLFSEDQSTFD 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031914857 155 ILQDLELPPVSPGKEPNGSPWRLDPLLDDGGLLSPISADDAFLLEGSLGEDCKPPLLSDTKPKINDRGDLL--PSSKMPM 232
Cdd:pfam02155 170 ILQDLELPPVSPGKETNGSPWRLDPLLDEGGLLSPLGADDPFLLEGNANEDCKPLILPDTKPKINETGDLLlsSASTSQL 249

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031914857 233 PQVKTEKEDYIELHTPGSIKQENTSPLYCQANFSSSNLLGTKVSAISIHGVSTSGGQMYHYDLNTASLSQQQDQKPIFNI 312
Cdd:pfam02155 250 PQVKTEKEDFIELCTPGVIKQEKLGTVYCQAGFPGANILGNKVSAISIHGVSTSGGQMYHYDLNTASVSQQQDQKPIFNM 329


                  ....*....
gi 1031914857 313 IPSLPAGSE 321
Cdd:pfam02155 330 IPPLPSGSE 338
 
Name Accession Description Interval E-value
GCR pfam02155
Glucocorticoid receptor;
1-321 1.64e-174

Glucocorticoid receptor;


Pssm-ID: 426625  Cd Length: 377  Bit Score: 488.23  E-value: 1.64e-174
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031914857   1 GGATVQAPVSTSPLPASSQSQSSQQPALADFPKGLGNNVPQPDLSKAVSLSMGLYMGETDAKVMGNDLGFSHQGQIGIPS 80
Cdd:pfam02155  10 GGARIKSTASSAPLAVVSQSDSKQQPVLGDFSKGLSNNATQPDLSKAVSLSMGLYMGETDTKVMGNDLGFPQQGQISFSS 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031914857  81 GETDFRLLEESIASLNKSSSLAEDAKGATSSAA------PDFPGMAGRGGPAEPGAAVQSQVGSNGGNVKLFSEDQSTLD 154
Cdd:pfam02155  90 GETDFRLLEESIASLNKSSSVPESLKGGVSPNLfplkteKDFPGMAKCDLSLEQDTFAQGQKGTNGGNLKLFSEDQSTFD 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031914857 155 ILQDLELPPVSPGKEPNGSPWRLDPLLDDGGLLSPISADDAFLLEGSLGEDCKPPLLSDTKPKINDRGDLL--PSSKMPM 232
Cdd:pfam02155 170 ILQDLELPPVSPGKETNGSPWRLDPLLDEGGLLSPLGADDPFLLEGNANEDCKPLILPDTKPKINETGDLLlsSASTSQL 249

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031914857 233 PQVKTEKEDYIELHTPGSIKQENTSPLYCQANFSSSNLLGTKVSAISIHGVSTSGGQMYHYDLNTASLSQQQDQKPIFNI 312
Cdd:pfam02155 250 PQVKTEKEDFIELCTPGVIKQEKLGTVYCQAGFPGANILGNKVSAISIHGVSTSGGQMYHYDLNTASVSQQQDQKPIFNM 329


                  ....*....
gi 1031914857 313 IPSLPAGSE 321
Cdd:pfam02155 330 IPPLPSGSE 338
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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