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Conserved domains on  [gi|1040783758|gb|ANN81725|]
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TonB-dependent receptor [Aggregatibacter actinomycetemcomitans D7S-1]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK13524 super family cl36254
FepA family TonB-dependent siderophore receptor;
12-502 3.54e-146

FepA family TonB-dependent siderophore receptor;


The actual alignment was detected with superfamily member PRK13524:

Pssm-ID: 237410 [Multi-domain]  Cd Length: 744  Bit Score: 436.38  E-value: 3.54e-146
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758  12 AETSTLYRQSYSLTHEGKWGS-FDNRTYFTFDQTRNYHYPEGLLGSTEGAYNglNKSVGF----LRNYRFSNELYIPFTL 86
Cdd:PRK13524  306 KETNRMYRQNYALTHRGGWDNgVSTSNYAQYEHTRNSRLPEGLAGGTEGIFN--EKATQFstidLDDVMLHSEVNLPFDL 383
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758  87 GsTGHMVTIGAEASRSELNDAASMTQTMQVYAIVPWLADKGRSGKVAQNEWAAFLEDNIMLpNNKTILTPGIRFDSSTNS 166
Cdd:PRK13524  384 L-VNQTLTLGTEWNQQRMKDPSSNTQALTSGGAIPGVSATGRSPYSKAEIFSLFAEDNMEL-TDSTMLTPGLRFDHHSIV 461
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 167 KSNWSPSFNFSHQVSENWKIKGGVARAYKAPNLYQSSPNYLLVNASNGCPIDSannwnnpnalnptgsngtrnnpytnsn 246
Cdd:PRK13524  462 GNNWSPSLNLSQGLGDDFTLKMGIARAYKAPNLYQTNPNYILYSKGQGCYASA--------------------------- 514
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 247 akgfdwGRACYFLGNENIKPETSWNKEIGFEYENEGKLFSLAYFHNDYRNKIVSngeflttidapagGYDREIRASNTpn 326
Cdd:PRK13524  515 ------GNGCYLQGNDDLKAETSVNKEIGLEFKRDGWLAGLTWFRNDYRNKIEA-------------GYVPVGTNSVG-- 573
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 327 gsaiyrnytATNVYRWGNTPRAIIEGLEGNITLPfLDDAILFSTNFTYMLKNENKQTGNPISLVPKYTVNSNLNWKINDH 406
Cdd:PRK13524  574 ---------KTDIYQWENVPKAVVEGLEGTLNVP-VSETVNWTNNLTYMLQSKNKTTGDPLSIIPEYTLNSTLSWQATED 643
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 407 WDINTSYTRYGKQKTVENAENFMQViytTGeSLVNQyhLGSYGSWGANFGYKFNDNLSLRLGVNNILDKRIYR--NAGT- 483
Cdd:PRK13524  644 LSLQSTFTWYGKQKPKKYNYKGQPV---TG-SATKE--VSPYSIVGLSATYDVTKNVSLTGGVDNLFDKRLWRegNAQTt 717
                         490       500
                  ....*....|....*....|....*..
gi 1040783758 484 --------ARTYNERGRSYFANLKYSF 502
Cdd:PRK13524  718 gdliagagAYTYNEPGRTYYMSLNTHF 744
 
Name Accession Description Interval E-value
PRK13524 PRK13524
FepA family TonB-dependent siderophore receptor;
12-502 3.54e-146

FepA family TonB-dependent siderophore receptor;


Pssm-ID: 237410 [Multi-domain]  Cd Length: 744  Bit Score: 436.38  E-value: 3.54e-146
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758  12 AETSTLYRQSYSLTHEGKWGS-FDNRTYFTFDQTRNYHYPEGLLGSTEGAYNglNKSVGF----LRNYRFSNELYIPFTL 86
Cdd:PRK13524  306 KETNRMYRQNYALTHRGGWDNgVSTSNYAQYEHTRNSRLPEGLAGGTEGIFN--EKATQFstidLDDVMLHSEVNLPFDL 383
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758  87 GsTGHMVTIGAEASRSELNDAASMTQTMQVYAIVPWLADKGRSGKVAQNEWAAFLEDNIMLpNNKTILTPGIRFDSSTNS 166
Cdd:PRK13524  384 L-VNQTLTLGTEWNQQRMKDPSSNTQALTSGGAIPGVSATGRSPYSKAEIFSLFAEDNMEL-TDSTMLTPGLRFDHHSIV 461
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 167 KSNWSPSFNFSHQVSENWKIKGGVARAYKAPNLYQSSPNYLLVNASNGCPIDSannwnnpnalnptgsngtrnnpytnsn 246
Cdd:PRK13524  462 GNNWSPSLNLSQGLGDDFTLKMGIARAYKAPNLYQTNPNYILYSKGQGCYASA--------------------------- 514
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 247 akgfdwGRACYFLGNENIKPETSWNKEIGFEYENEGKLFSLAYFHNDYRNKIVSngeflttidapagGYDREIRASNTpn 326
Cdd:PRK13524  515 ------GNGCYLQGNDDLKAETSVNKEIGLEFKRDGWLAGLTWFRNDYRNKIEA-------------GYVPVGTNSVG-- 573
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 327 gsaiyrnytATNVYRWGNTPRAIIEGLEGNITLPfLDDAILFSTNFTYMLKNENKQTGNPISLVPKYTVNSNLNWKINDH 406
Cdd:PRK13524  574 ---------KTDIYQWENVPKAVVEGLEGTLNVP-VSETVNWTNNLTYMLQSKNKTTGDPLSIIPEYTLNSTLSWQATED 643
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 407 WDINTSYTRYGKQKTVENAENFMQViytTGeSLVNQyhLGSYGSWGANFGYKFNDNLSLRLGVNNILDKRIYR--NAGT- 483
Cdd:PRK13524  644 LSLQSTFTWYGKQKPKKYNYKGQPV---TG-SATKE--VSPYSIVGLSATYDVTKNVSLTGGVDNLFDKRLWRegNAQTt 717
                         490       500
                  ....*....|....*....|....*..
gi 1040783758 484 --------ARTYNERGRSYFANLKYSF 502
Cdd:PRK13524  718 gdliagagAYTYNEPGRTYYMSLNTHF 744
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
13-502 5.21e-52

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 186.50  E-value: 5.21e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758  13 ETSTLYRQSYSLTHEGKWGSFDNRTYFTFDQTRNYHYPEGLLGSTEGAY----NGLNKSVGFLRNYRFSNELYIPFTLGS 88
Cdd:cd01347   235 RDRYRKRASLGLEHDLNDTGWTLRANLSYSYTDNDGDPLILNGGNNAAGgdlgRSGYSSERDTTQLGFDAGLNAPFGTGP 314
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758  89 TGHMVTIGAEASRSELNdaasmtqtmqvyaivpwladkgrsgkvaQNEWAAFLEDNIMLpNNKTILTPGIRFD------- 161
Cdd:cd01347   315 VAHTLTLGVEYRREELD----------------------------EKQTALYAQDTIEL-TDDLTLTLGLRYDhydqdsk 365
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 162 -------SSTNSKSNWSPSFNFSHQVSENWKIKGGVARAYKAPNLYQSSPNYLLVNasngcpidsannwnnpnalnptgs 234
Cdd:cd01347   366 dtiaggtTAKKSYSHWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELYGGGSHGG------------------------ 421
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 235 ngtrnnpytnsnakgfdwgraCYFLGNENIKPETSWNKEIGFEYENEGKL-FSLAYFHNDYRNKIVSNgeflttidapag 313
Cdd:cd01347   422 ---------------------TAAVGNPNLKPEKSKQYELGLKYDPGDGLtLSAALFRIDIKNEIVST------------ 468
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 314 gydreirasntpngsaiYRNYTATNVYRWGNTPRAIIEGLEGNITLPFLDDaILFSTNFTYM----LKNENKQTGNPISL 389
Cdd:cd01347   469 -----------------PTNTGLGLVTVYVNGGKARIRGVELEASYDLTDG-LGLTGSYTYTdtevKRTDGATTGNRLPG 530
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 390 VPKYTVNSNLNWKIN-DHWDINTSYTRYGKQKTVENAENfmqviyttgeslvNQYHLGSYGSWGANFGYKFNDNLSLRLG 468
Cdd:cd01347   531 IPKHTANLGLDYELPdEGLTAGGGVRYRGKQYADTANGN-------------NTVKVPGYTLVDLSASYQFTKNLTLRLG 597
                         490       500       510
                  ....*....|....*....|....*....|....*...
gi 1040783758 469 VNNILDKRIYRNAGTAR----TYNERGRSYFANLKYSF 502
Cdd:cd01347   598 VNNLFDKDYYTSLSVRGsglyGYYGPGRTYYLSVSYKF 635
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
2-466 9.45e-38

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 146.15  E-value: 9.45e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758   2 QTSRQLALQKAETSTLYRQSYSLTHEGKWG-SFDNRTYFTFDQTRNYHYPEGLLGSTEGAYNGLNKSVGFLRNYRFSNel 80
Cdd:COG4771   256 DTEISSDNAGDRDTTTDRGNYSLRYNGDLGdNLDLSLYYSRTDRDSTNGSLGGSTGSFSDSDDTTYGLELDLTYPLGG-- 333
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758  81 yipftlgstGHMVTIGAEASRSELNDAASMTQTmqvyaivpwladkgrsgKVAQNEWAAFLEDNIMLpNNKTILTPGIRF 160
Cdd:COG4771   334 ---------NHTLTLGAEYRYDDLDSSSFLGGA-----------------DASRDTYGLFAQDEWKL-TDKLTLTAGLRY 386
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 161 DSST----NSKSNWSPSFNFSHQVSENWKIKGGVARAYKAPNLYQSSPNYllvnasngcpidsannwnnpnalnptgsng 236
Cdd:COG4771   387 DYYStfgaSNYTAFSPRLGLRYDLSDNLTLRASYGRGFRAPSLAELYGSG------------------------------ 436
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 237 trnnpytnsnakgfDWGRACYFLGNENIKPETSWNKEIGFEYENEGK--LFSLAYFHNDYRNKIVSNgeflttidapagg 314
Cdd:COG4771   437 --------------TGTPGRYVLGNPDLKPETSDNYELGLEYRLGNGglSLSLTGFYTDIKDLIVLV------------- 489
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 315 ydreirasntpngsaiYRNYTATNVYRWGNTPRAIIEGLEGNITLPFLDDaILFSTNFTYM-LKNENKQTGNPISLVPKY 393
Cdd:COG4771   490 ----------------PVGPGPGDVLQYENVGKARTYGLELELKYRLGKG-LTLTASYTYLdSKIDDGDTGEPLPNVPPH 552
                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1040783758 394 TVNSNLNWKINDHWDINTSYTRYGKQktvenaenfmqviYTTGESLVNQYHLGSYGSWGANFGYKFNDNLSLR 466
Cdd:COG4771   553 KANLGLDYRLPKWWLLLLLTRYYGGR-------------YVTPPSGRLEGYTPGYTLLDLRASYKLTKNLTLS 612
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
19-501 7.92e-31

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 124.88  E-value: 7.92e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758  19 RQSYSLTHEGKWGsFDNRTYFTFDQTRNYHYPEGLLGSTEGAYNGLNKSVGFLRNYRFSNELYIPFTLGSTGHMVTIGAE 98
Cdd:pfam00593  60 RKRLSLGYDYDLG-DGLSWLSTLRLGLRYSSLDGDYTSNSSGLSGAGDYLSDDRLYGLYGLDGDLELSLDLSHDLLLGVE 138
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758  99 ASRSELNdaASMTQTMQVYAIVPWLADKGRSGKVAQNEWAAFLEDNIMLpNNKTILTPGIRFDSST-------------- 164
Cdd:pfam00593 139 LRTAGLD--YRRLDDDAYDPYDPANPSSSSYSDTTTDSYGLYLQDNIKL-TDRLTLTLGLRYDHYStdgddgngggdnfs 215
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 165 NSKSNWSPSFNFSHQVSENWKIKGGVARAYKAPNLYQSSPNYLLVNASNgcpidsannwnnpnalnptgsngtrnnpytn 244
Cdd:pfam00593 216 RSYSAFSPRLGLVYKPTDNLSLYASYSRGFRAPSLGELYGSGSGGGGGA------------------------------- 264
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 245 snakgfdwgracYFLGNENIKPETSWNKEIGFEYENEGKLFSLAYFHNDYRNKIVSNGEflttidapaggydreirasnt 324
Cdd:pfam00593 265 ------------VAGGNPDLKPETSDNYELGLKYDDGRLSLSLALFYIDIKNLITSDPD--------------------- 311
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 325 pngsaiyRNYTATNVYRWGNTPRAIIEGLEGNITLPFLDDaILFSTNFTYMLKNENKQ---TGNPISLVPKYTVNSNLNW 401
Cdd:pfam00593 312 -------GPGLGGTVYTYTNVGKARIRGVELELSGRLWGL-GLSGGGYTYTDADDDADaddTGNPLPNVPRHTANLGLTY 383
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 402 KI-NDHWDINTSYTRYGKQKTVENAENfmqviyttgeslvNQYHLGSYGSWGANFGYKFNDNLSLRLGVNNILDKRIYR- 479
Cdd:pfam00593 384 DFpLGGWGARLGARYVGSGERRYGDAA-------------NTFKTPGYTLVDLSAGYRLNKNLTLRLGVNNLFDKYYKRy 450
                         490       500
                  ....*....|....*....|....*
gi 1040783758 480 ---NAGTARTYNERGRSYFANLKYS 501
Cdd:pfam00593 451 yssGGGNLGGYPGPGRTFYLGLSYK 475
TonB-hemlactrns TIGR01786
TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model ...
21-502 5.00e-24

TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model represents a family of TonB-dependent outer membrane receptor/transporters acting on iron-containing proteins such as hemoglobin, transferrin and lactoferrin. Two subfamily models with a narrower scope are contained within this model, the heme/hemoglobin receptor family protein model (TIGR01785) and the transferrin/lactoferrin receptor family model (TIGR01776). Accessions which score above trusted to this model while not scoring above trusted to the more specific models are most likely to be hemoglobin transporters. Nearly all of the species containing trusted hits to this model have access to hemoglobin, transferrin or lactoferrin or related proteins in their biological niche. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273808 [Multi-domain]  Cd Length: 715  Bit Score: 105.96  E-value: 5.00e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758  21 SYSLTHEGKWgsFDNRTYFTFDQT-RNYHYpeglLGSTEGAYNGLNKSVGFLRN----YRFSNELYIPFTLGSTGHMVTI 95
Cdd:TIGR01786 278 DYELNPDNSW--LDTVKLALDKQYiQLYNY----LNATSASDYPGVDKNGRYKDkydyYTLGFDTNNKIEFSVHSLSLTY 351
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758  96 GAEASRSELNdAASMTQTMQVYAIVPwLADKGRSGKVAQNEWAAFLEDNIMLpNNKTILTPGIRFD-------------- 161
Cdd:TIGR01786 352 GLDRFKDKVS-TGDSRRNLPTAAYNL-YGYEGENRPVKGSNFGLFLQDNIKL-GDWLSLSAGLRYDhyktdpkadeskdy 428
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 162 -SSTNSKSNWSPSFNFSHQVSENWKIKGGVARAYKAPNLYQSspnyllvnasngcpidsannwnnpnalnptgsngtrnn 240
Cdd:TIGR01786 429 gAISKTYSRWSPSLGLTYKPTPWLTLYYSYSQGFRAPSFDEL-------------------------------------- 470
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 241 pYTNSNAKGFDwgrACYFLGNENIKPETSWNKEIGFEYENEGKLFSLAYFHNDYRNKIvsngefLTTIDAPAGGYDREIR 320
Cdd:TIGR01786 471 -YGTGAHPGGG---PYTFLPNPNLKPETSKNWEIGINLHFDQLDFKVSYFRNDYKDFI------DLGIGVTAKGNMAQVG 540
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 321 ASNTPNgsaiYRNytATNVYRWGntpraiIEgLEGNI---TLPFLDDAILFSTNFTYMlKNENKQTGNPISLVPKYTVNS 397
Cdd:TIGR01786 541 SNTITN----YVN--IDNARIRG------IE-LSGRYdlgSFFSGPDGWTTTLKYGYT-KGKDSDTNPWLNAITPLKVVL 606
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 398 NLNWKI-NDHWDINTSYTRYGKQKTVENAENFmqviYTTGESLVNQYHL-GSYGSWGANFGYKFNDNLSLRLGVNNILDK 475
Cdd:TIGR01786 607 GLGYDHpDEKWGVGLTLTFSGAKDAVDAYATY----YENGEAAKAGPLRtPSYTVVDLYGYYKPNKNLTLRFGVYNLLDR 682
                         490       500       510
                  ....*....|....*....|....*....|...
gi 1040783758 476 R-----IYRNAGT-ARTYNERGRSYFANLKYSF 502
Cdd:TIGR01786 683 KyttweSARQAGPlATGYTAPGRNYKASVEYKF 715
 
Name Accession Description Interval E-value
PRK13524 PRK13524
FepA family TonB-dependent siderophore receptor;
12-502 3.54e-146

FepA family TonB-dependent siderophore receptor;


Pssm-ID: 237410 [Multi-domain]  Cd Length: 744  Bit Score: 436.38  E-value: 3.54e-146
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758  12 AETSTLYRQSYSLTHEGKWGS-FDNRTYFTFDQTRNYHYPEGLLGSTEGAYNglNKSVGF----LRNYRFSNELYIPFTL 86
Cdd:PRK13524  306 KETNRMYRQNYALTHRGGWDNgVSTSNYAQYEHTRNSRLPEGLAGGTEGIFN--EKATQFstidLDDVMLHSEVNLPFDL 383
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758  87 GsTGHMVTIGAEASRSELNDAASMTQTMQVYAIVPWLADKGRSGKVAQNEWAAFLEDNIMLpNNKTILTPGIRFDSSTNS 166
Cdd:PRK13524  384 L-VNQTLTLGTEWNQQRMKDPSSNTQALTSGGAIPGVSATGRSPYSKAEIFSLFAEDNMEL-TDSTMLTPGLRFDHHSIV 461
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 167 KSNWSPSFNFSHQVSENWKIKGGVARAYKAPNLYQSSPNYLLVNASNGCPIDSannwnnpnalnptgsngtrnnpytnsn 246
Cdd:PRK13524  462 GNNWSPSLNLSQGLGDDFTLKMGIARAYKAPNLYQTNPNYILYSKGQGCYASA--------------------------- 514
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 247 akgfdwGRACYFLGNENIKPETSWNKEIGFEYENEGKLFSLAYFHNDYRNKIVSngeflttidapagGYDREIRASNTpn 326
Cdd:PRK13524  515 ------GNGCYLQGNDDLKAETSVNKEIGLEFKRDGWLAGLTWFRNDYRNKIEA-------------GYVPVGTNSVG-- 573
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 327 gsaiyrnytATNVYRWGNTPRAIIEGLEGNITLPfLDDAILFSTNFTYMLKNENKQTGNPISLVPKYTVNSNLNWKINDH 406
Cdd:PRK13524  574 ---------KTDIYQWENVPKAVVEGLEGTLNVP-VSETVNWTNNLTYMLQSKNKTTGDPLSIIPEYTLNSTLSWQATED 643
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 407 WDINTSYTRYGKQKTVENAENFMQViytTGeSLVNQyhLGSYGSWGANFGYKFNDNLSLRLGVNNILDKRIYR--NAGT- 483
Cdd:PRK13524  644 LSLQSTFTWYGKQKPKKYNYKGQPV---TG-SATKE--VSPYSIVGLSATYDVTKNVSLTGGVDNLFDKRLWRegNAQTt 717
                         490       500
                  ....*....|....*....|....*..
gi 1040783758 484 --------ARTYNERGRSYFANLKYSF 502
Cdd:PRK13524  718 gdliagagAYTYNEPGRTYYMSLNTHF 744
PRK13528 PRK13528
outer membrane receptor FepA; Provisional
7-502 3.61e-144

outer membrane receptor FepA; Provisional


Pssm-ID: 237413 [Multi-domain]  Cd Length: 727  Bit Score: 430.72  E-value: 3.61e-144
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758   7 LALQKAETSTLYRQSYSLTHEGKWGSFDNRTYFTFDQTRNYHYPEGLLGSTEGAYN-GLNKSVGFLRNYRFSNELYIPFT 85
Cdd:PRK13528  294 LAKSGKETNRLYRQNYGLTHNGIWDWGQSRLGFYYEKTNNTRMNEGLAGGGEGRITaDQTFTTSRLESYRTSGELNVPLN 373
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758  86 LGSTgHMVTIGAEASRSELNDAASMTQTMQVYAIVPWLADKG-RSGKVAQNEWAAFLEDNIMlPNNKTILTPGIRFDSST 164
Cdd:PRK13528  374 WLFE-QTLTVGAEWNRDELNDPSSTSLTVKDGDIGGISGSAAdRSSKNKSEISALYVEDNIE-PVPGTNLIPGLRFDYHS 451
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 165 NSKSNWSPSFNFSHQVSENWKIKGGVARAYKAPNLYQSSPNYLLVNASNGCPIDsannwnnpnalnpTGSNGtrnnpytn 244
Cdd:PRK13528  452 EFGSNWSPSLNLSQELGDYFKVKAGIARAFKAPNLYQSSEGYLLYSRGNGCPKD-------------ITSGG-------- 510
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 245 snakgfdwgraCYFLGNENIKPETSWNKEIGFEYENEGKLFSLAYFHNDYRNKIVSngeflttidapagGYDreirasnt 324
Cdd:PRK13528  511 -----------CYLVGNKNLDPEISVNKEIGLEFTVDDYHASVTYFRNDYQNKIVA-------------GDD-------- 558
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 325 pngsAIYRNYTATNVYRWGNTPRAIIEGLEGNITLPFLDDAILFSTNFTYMLKNENKQTGNPISLVPKYTVNSNLNWKIN 404
Cdd:PRK13528  559 ----VIGRTASGAYILQWQNGGKAVVEGLEGNLLVPLMKDRLNWNTNATYMITSEQKDTGNPLSVIPKYTINSTLDWQIT 634
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 405 DHWDINTSYTRYGKQKTVENAENfmQVIYTTGESLvnqYHLGSYGSWGANFGYKFNDNLSLRLGVNNILDKRIYRNAGTA 484
Cdd:PRK13528  635 QALSANVNWTLYGKQKPRTHAES--RSEETGGLSG---KELGAYSLVGVNVNYDINKNLRLNVGVSNLFDKQIYREGEGA 709
                         490
                  ....*....|....*...
gi 1040783758 485 RTYNERGRSYFANLKYSF 502
Cdd:PRK13528  710 NTYNEPGRAYYAGVTASF 727
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
13-502 5.21e-52

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 186.50  E-value: 5.21e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758  13 ETSTLYRQSYSLTHEGKWGSFDNRTYFTFDQTRNYHYPEGLLGSTEGAY----NGLNKSVGFLRNYRFSNELYIPFTLGS 88
Cdd:cd01347   235 RDRYRKRASLGLEHDLNDTGWTLRANLSYSYTDNDGDPLILNGGNNAAGgdlgRSGYSSERDTTQLGFDAGLNAPFGTGP 314
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758  89 TGHMVTIGAEASRSELNdaasmtqtmqvyaivpwladkgrsgkvaQNEWAAFLEDNIMLpNNKTILTPGIRFD------- 161
Cdd:cd01347   315 VAHTLTLGVEYRREELD----------------------------EKQTALYAQDTIEL-TDDLTLTLGLRYDhydqdsk 365
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 162 -------SSTNSKSNWSPSFNFSHQVSENWKIKGGVARAYKAPNLYQSSPNYLLVNasngcpidsannwnnpnalnptgs 234
Cdd:cd01347   366 dtiaggtTAKKSYSHWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELYGGGSHGG------------------------ 421
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 235 ngtrnnpytnsnakgfdwgraCYFLGNENIKPETSWNKEIGFEYENEGKL-FSLAYFHNDYRNKIVSNgeflttidapag 313
Cdd:cd01347   422 ---------------------TAAVGNPNLKPEKSKQYELGLKYDPGDGLtLSAALFRIDIKNEIVST------------ 468
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 314 gydreirasntpngsaiYRNYTATNVYRWGNTPRAIIEGLEGNITLPFLDDaILFSTNFTYM----LKNENKQTGNPISL 389
Cdd:cd01347   469 -----------------PTNTGLGLVTVYVNGGKARIRGVELEASYDLTDG-LGLTGSYTYTdtevKRTDGATTGNRLPG 530
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 390 VPKYTVNSNLNWKIN-DHWDINTSYTRYGKQKTVENAENfmqviyttgeslvNQYHLGSYGSWGANFGYKFNDNLSLRLG 468
Cdd:cd01347   531 IPKHTANLGLDYELPdEGLTAGGGVRYRGKQYADTANGN-------------NTVKVPGYTLVDLSASYQFTKNLTLRLG 597
                         490       500       510
                  ....*....|....*....|....*....|....*...
gi 1040783758 469 VNNILDKRIYRNAGTAR----TYNERGRSYFANLKYSF 502
Cdd:cd01347   598 VNNLFDKDYYTSLSVRGsglyGYYGPGRTYYLSVSYKF 635
PRK10064 PRK10064
catecholate siderophore receptor CirA; Provisional
17-502 2.82e-41

catecholate siderophore receptor CirA; Provisional


Pssm-ID: 236646 [Multi-domain]  Cd Length: 663  Bit Score: 156.97  E-value: 2.82e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758  17 LYRQSYSLTHEGKWGSFDNRTYFTFDQTRNYhypegllgstegayNGLNKSVGFLRNYRFSNELYIPftLGSTGHMVTIG 96
Cdd:PRK10064  272 LERQNYSLSHNGRWDYGNSELKYYGEKVENK--------------NPGNSSPITSESNSIDGKYTLP--LTAINQFLTFG 335
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758  97 AEASRSELNDAASMTqtmqvyaivpwladKGRSGKVAQNEWAAFLEDNIMLpNNKTILTPGIRFDSSTNSKSNWSPSFNF 176
Cdd:PRK10064  336 GEWRHDKLSDAVNLT--------------GGTSSKTSASQYALFVEDEWRI-FEPLALTTGVRMDDHETYGDHWSPRAYL 400
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 177 SHQVSENWKIKGGVARAYKAPNLYQSSPNYllvnASNGCpidsannwnnpnalnptgsngtrnnpytnsnakgfdwGRAC 256
Cdd:PRK10064  401 VYNATDTVTVKGGWATAFKAPSLLQLSPDW----TSNSC-------------------------------------RGAC 439
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 257 YFLGNENIKPETSWNKEIGFEYENE-----GKLFSLAYFHNDYRNKIvsngEFLTTIDAP-AGGYDREIRASNTPNGSAI 330
Cdd:PRK10064  440 KIVGSPDLKPETSESWELGLYYMGEegwleGVESSVTVFRNDVDDRI----SISRTSDVNaAPGYQNFVGFETNGRGRRV 515
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 331 yrnytatNVYRWGNTPRAIIEGLEGNITLPFLDDAILfSTNFTYMLKNENKQTGN-PISLVPKYTVNSNLNWK--INDHW 407
Cdd:PRK10064  516 -------PVFRYYNVNKARIQGVETELKIPFNDEWKL-SLNYTYNDGRDVSNGENkPLSDLPFHTANGTLDWKplALEDW 587
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 408 DINTSYTRYGKQKTVENAenfmqvIYTTGEslvnqyhlgsYGSWGANFGYKFNDNLSLRLGVNNILDKRIYRNagtARTY 487
Cdd:PRK10064  588 SFYVSGNYTGQKRADSAT------AKTPGG----------YTIWNTGAAWQVTKDVKLRAGVLNLGDKDLSRD---DYSY 648
                         490
                  ....*....|....*
gi 1040783758 488 NERGRSYFANLKYSF 502
Cdd:PRK10064  649 NEDGRRYFMAVDYRF 663
PRK13483 PRK13483
ligand-gated channel protein;
12-502 1.46e-38

ligand-gated channel protein;


Pssm-ID: 184080 [Multi-domain]  Cd Length: 660  Bit Score: 149.16  E-value: 1.46e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758  12 AETSTLYRQS-YSLTHEGKWGSFDNRTYFTFDQTRNyhypegllgstegaynglnKSVGF-LRNYRFSNELYIPftLGST 89
Cdd:PRK13483  281 ESSTTEYERStVSLSHTGRWDFGTSDTYIQHEEFDN-------------------KSREMkIKNTDFQSSLVAP--LGQE 339
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758  90 gHMVTIGAEASRSELNDAASMTqtmqvyaivpwLADKGRsgkVAQNEWAAFLEDNIMLPNNKTiLTPGIRFDSSTNSKSN 169
Cdd:PRK13483  340 -HTLTFGAAYNHQDLTDETSNQ-----------ISDLTD---ISRTQWAVFSEDEWRIADDFA-LTGGLRLDHDENFGGH 403
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 170 WSPSFNFSHQVSENWKIKGGVARAYKAPNLYQSSPnyllvnasngcpidsannwnnpnalnptgsngtrnnpytnsnakg 249
Cdd:PRK13483  404 VSPRVYGVWNLAPSWTVKGGVSTGFRAPSLRQTTP--------------------------------------------- 438
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 250 fDWG---RACYFLGNENIKPETSWNKEIGFEYE-NEGKLFSLAYFHNDYRNKIvsngeflTTIDAPAggydreIRASNTP 325
Cdd:PRK13483  439 -DWGqvsRGGNIYGNPDLKPETSLNKELGLYYDlGSGLTASLTVFYNEFKDKI-------TRVACPA------TQCTDGP 504
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 326 N--GSAiyrnyTATNVyrwgNTPRAIIEGLEGNITLPFLdDAILFSTNFTYMlKNENKQ---TGNPISLVPKYTVNSNLN 400
Cdd:PRK13483  505 NqfGAD-----PTTYV----NIDEAVTQGVEASLSYPIT-STLSLSGNYTYT-DSEQKSgayKGSPLNQLPKHLFQASLN 573
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 401 WKINDHWDINTSYTRYGKQK---TVENAENFMQVIYTTGESlvnqyhlgsygswGANfgYKFNDNLSLRLGVNNILDKRI 477
Cdd:PRK13483  574 WEPTDRLNSWARVNYRGEESqptTGPSSSSFIAPSYTFLDL-------------GAN--YQLTDNLKLSAGIYNLFDKEI 638
                         490       500
                  ....*....|....*....|....*.
gi 1040783758 478 -YRNAGtartYNERGRSYFANLKYSF 502
Cdd:PRK13483  639 nYEEYG----YVEDGRRYWLGMTYSF 660
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
2-466 9.45e-38

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 146.15  E-value: 9.45e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758   2 QTSRQLALQKAETSTLYRQSYSLTHEGKWG-SFDNRTYFTFDQTRNYHYPEGLLGSTEGAYNGLNKSVGFLRNYRFSNel 80
Cdd:COG4771   256 DTEISSDNAGDRDTTTDRGNYSLRYNGDLGdNLDLSLYYSRTDRDSTNGSLGGSTGSFSDSDDTTYGLELDLTYPLGG-- 333
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758  81 yipftlgstGHMVTIGAEASRSELNDAASMTQTmqvyaivpwladkgrsgKVAQNEWAAFLEDNIMLpNNKTILTPGIRF 160
Cdd:COG4771   334 ---------NHTLTLGAEYRYDDLDSSSFLGGA-----------------DASRDTYGLFAQDEWKL-TDKLTLTAGLRY 386
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 161 DSST----NSKSNWSPSFNFSHQVSENWKIKGGVARAYKAPNLYQSSPNYllvnasngcpidsannwnnpnalnptgsng 236
Cdd:COG4771   387 DYYStfgaSNYTAFSPRLGLRYDLSDNLTLRASYGRGFRAPSLAELYGSG------------------------------ 436
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 237 trnnpytnsnakgfDWGRACYFLGNENIKPETSWNKEIGFEYENEGK--LFSLAYFHNDYRNKIVSNgeflttidapagg 314
Cdd:COG4771   437 --------------TGTPGRYVLGNPDLKPETSDNYELGLEYRLGNGglSLSLTGFYTDIKDLIVLV------------- 489
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 315 ydreirasntpngsaiYRNYTATNVYRWGNTPRAIIEGLEGNITLPFLDDaILFSTNFTYM-LKNENKQTGNPISLVPKY 393
Cdd:COG4771   490 ----------------PVGPGPGDVLQYENVGKARTYGLELELKYRLGKG-LTLTASYTYLdSKIDDGDTGEPLPNVPPH 552
                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1040783758 394 TVNSNLNWKINDHWDINTSYTRYGKQktvenaenfmqviYTTGESLVNQYHLGSYGSWGANFGYKFNDNLSLR 466
Cdd:COG4771   553 KANLGLDYRLPKWWLLLLLTRYYGGR-------------YVTPPSGRLEGYTPGYTLLDLRASYKLTKNLTLS 612
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
19-501 7.92e-31

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 124.88  E-value: 7.92e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758  19 RQSYSLTHEGKWGsFDNRTYFTFDQTRNYHYPEGLLGSTEGAYNGLNKSVGFLRNYRFSNELYIPFTLGSTGHMVTIGAE 98
Cdd:pfam00593  60 RKRLSLGYDYDLG-DGLSWLSTLRLGLRYSSLDGDYTSNSSGLSGAGDYLSDDRLYGLYGLDGDLELSLDLSHDLLLGVE 138
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758  99 ASRSELNdaASMTQTMQVYAIVPWLADKGRSGKVAQNEWAAFLEDNIMLpNNKTILTPGIRFDSST-------------- 164
Cdd:pfam00593 139 LRTAGLD--YRRLDDDAYDPYDPANPSSSSYSDTTTDSYGLYLQDNIKL-TDRLTLTLGLRYDHYStdgddgngggdnfs 215
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 165 NSKSNWSPSFNFSHQVSENWKIKGGVARAYKAPNLYQSSPNYLLVNASNgcpidsannwnnpnalnptgsngtrnnpytn 244
Cdd:pfam00593 216 RSYSAFSPRLGLVYKPTDNLSLYASYSRGFRAPSLGELYGSGSGGGGGA------------------------------- 264
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 245 snakgfdwgracYFLGNENIKPETSWNKEIGFEYENEGKLFSLAYFHNDYRNKIVSNGEflttidapaggydreirasnt 324
Cdd:pfam00593 265 ------------VAGGNPDLKPETSDNYELGLKYDDGRLSLSLALFYIDIKNLITSDPD--------------------- 311
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 325 pngsaiyRNYTATNVYRWGNTPRAIIEGLEGNITLPFLDDaILFSTNFTYMLKNENKQ---TGNPISLVPKYTVNSNLNW 401
Cdd:pfam00593 312 -------GPGLGGTVYTYTNVGKARIRGVELELSGRLWGL-GLSGGGYTYTDADDDADaddTGNPLPNVPRHTANLGLTY 383
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 402 KI-NDHWDINTSYTRYGKQKTVENAENfmqviyttgeslvNQYHLGSYGSWGANFGYKFNDNLSLRLGVNNILDKRIYR- 479
Cdd:pfam00593 384 DFpLGGWGARLGARYVGSGERRYGDAA-------------NTFKTPGYTLVDLSAGYRLNKNLTLRLGVNNLFDKYYKRy 450
                         490       500
                  ....*....|....*....|....*
gi 1040783758 480 ---NAGTARTYNERGRSYFANLKYS 501
Cdd:pfam00593 451 yssGGGNLGGYPGPGRTFYLGLSYK 475
PRK13513 PRK13513
ligand-gated channel protein;
5-502 3.33e-29

ligand-gated channel protein;


Pssm-ID: 184104 [Multi-domain]  Cd Length: 659  Bit Score: 121.41  E-value: 3.33e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758   5 RQLALQKAETSTLY-RQSYSLTHEGKWGSFDNRTYFTFDQTRNyhyPEGLLGSTEGAYNglNKSVgflrnyrfsnelyip 83
Cdd:PRK13513  265 RTLALNGTNSDTQYdRNNYAITHNGYYDFGNSTSYIQRDETRN---PSRQMKSVDTIFN--TQTS--------------- 324
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758  84 FTLGStgHMVTIGAEASRSELNDAASMtqtmqvyaivpwLADKGRSGKVAQNEWAAFLEDNIMLPNNKTiLTPGIRFDSS 163
Cdd:PRK13513  325 FLLDD--HTLSLGGQYRYEELYDKGNQ------------LPSASDLNKLTRWSWALFAEDEWQMTNDFA-LTGGIRMDQD 389
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 164 TNSKSNWSPSFNFSHQVSENWKIKGGVARAYKAPNLYQSSPNYllvnasngcpidsannwnnpnaLNPTGSnGTRNNpyt 243
Cdd:PRK13513  390 QNYGTHWTPRLYGVWHLADQWTLKGGVSTGYRSPDLRQATDNW----------------------GQLTGG-GGLPA--- 443
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 244 nsnakgfdwgracYFLGNENIKPETSWNKEIGFEYENEGKL-FSLAYFHNDYRNKIVsngeflttidapaggydrEIRAS 322
Cdd:PRK13513  444 -------------LILGNSDLKPEKSISQEIGILWDNQENLnASVTLFNTDFKDKIT------------------EVRNC 492
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 323 NTPNGSA--IYRNYTATNVYRWGNTPRAIIEGLEGNITLPFLDDAILfSTNFTYMlKNENKQ---TGNPISLVPKYTVNS 397
Cdd:PRK13513  493 DTTNTDGqcVFNGINYDFISDRINVDKANMRGVEATFNWDINQAWSL-ATNYTFT-QSEQKSgafAGQPLNQMPKHMANA 570
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 398 NLNWKINDHWdinTSYTRYG-KQKTVEnaenfmqviYTTGESLVNQyhLGSYGSWGANFGYKFNDNLSLRLGVNNILDKR 476
Cdd:PRK13513  571 TLNWQTTEDF---ATWIRINyRGKTSE---------YLNRTSMGSG--TPSYTFVDLGASYQLTKELRLMGGVYNLLDKR 636
                         490       500
                  ....*....|....*....|....*...
gi 1040783758 477 IyrnagTARTYNE--RGRSYFANLKYSF 502
Cdd:PRK13513  637 V-----DIDVNDKvlDGRRYMVGASYDF 659
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
14-491 9.40e-28

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 117.24  E-value: 9.40e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758  14 TSTLYRQSYSLTHEGKWGSFDNRTYFTFDQTRNYHYpeglLGSTEGAYNGLNKSVGFLRNYRFSNELYIPFTLGStGHMV 93
Cdd:COG1629   242 TRDRYSLSLEYEHLGDGLKLSASAYYRYDDTDLDSD----FTPTPADGGTLEQTDFDNRTYGLELRLTYDLGFGG-KHTL 316
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758  94 TIGAEASRSELNDAASMTQtmqVYAIVPWLADKGRSGKVAQNEWAAFLEDNIMLpNNKTILTPGIRFD------------ 161
Cdd:COG1629   317 LVGLDYQRQDLDGSGYPLD---LGSGSLPTLTSGADDDGTTTSLALYAQDTYKL-TDKLTLTAGLRYDyvsydvddtvtg 392
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 162 ----SSTNSKSNWSPSFNFSHQVSENWKIKGGVARAYKAPNLYQSSPNyllvnasngcpidsannwnnpnalnptgsngt 237
Cdd:COG1629   393 tdsaSGSRSYSAFSPSLGLTYQLSPNLSLYASYSRGFRAPTFGELYAN-------------------------------- 440
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 238 rnnpytnsnakgfdwGRACYFLGNENIKPETSWNKEIGFEYE--NEGKLFSLAYFHNDYRNKIVSngeflttidapaggy 315
Cdd:COG1629   441 ---------------GTDPYSVGNPDLKPETSTNYELGLRYRllDGRLSLSLALFYSDVDNEILS--------------- 490
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 316 dreIRASNTPNGSAIYRNYTATNVYrwgntpraiieGLEGNITLPFLDDailFSTNFTY-MLKNENK--------QTGNP 386
Cdd:COG1629   491 ---VPLPNDSGFSTYYTNAGKARSY-----------GVELELSYQLTPG---LSLNASYsYTDAKFDddtdgsadLDGNR 553
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 387 ISLVPKYTVNSNLNWKINDHWDINTSYTRYGKQKTVENAenfmqviyttgeslvNQYHLGSYGSWGANFGYKFNDNLSLR 466
Cdd:COG1629   554 LPGVPPLTANLGLTYEFPGGWSLGLGVRYVGDRYLDDAN---------------TQGAPGGYTLVDLGAGYRFGDNLTLS 618
                         490       500
                  ....*....|....*....|....*
gi 1040783758 467 LGVNNILDKRiYRNAGTARTYNERG 491
Cdd:COG1629   619 LGVDNLFDKK-YATSLSVRASNVRG 642
FecA COG4772
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
19-502 5.76e-27

Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];


Pssm-ID: 443804 [Multi-domain]  Cd Length: 681  Bit Score: 114.64  E-value: 5.76e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758  19 RQSYSLTHEGKWG---SFDNRTYFTfDQTRNYHYPegllGSTEGAYNGLNKSVGFLRNYR---FSNELYIPFTLGSTGHM 92
Cdd:COG4772   266 RTQLSLRYEHQLSdntTLTTTAYYN-DFSRNWYIR----QNTADPNTPGLGLRGNPRGYRsygIEPRLTHRFELGGVPHT 340
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758  93 VTIGAEASRSELNDaasmtqtmQVYAIVPWLADKGRSGKVAQNE----WAAFLEDNIMLPNNKTIlTPGIRF-------- 160
Cdd:COG4772   341 LEVGLRYHREEEDR--------KQYVNTYGQGRSGAGLRRDRRFsadaLAAYAQNRFELTGRLTL-TPGLRYehirrdrt 411
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 161 ----------DSSTNSKSNWSPSFNFSHQVSENWKIKGGVARAYKAPNLYQSSPNyllvnasngcpidsannwnnpnaln 230
Cdd:COG4772   412 drystrtggdDSGSNSYSEFLPGLGLLYQLTDNLQLYANVSRGFEPPTFGDLAYG------------------------- 466
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 231 ptgsNGtrnnpytnsnakgfdwgracyflGNENIKPETSWNKEIGFEYENEGKL-FSLAYFHNDYRNKIVSngeflttiD 309
Cdd:COG4772   467 ----NG-----------------------GNPDLKPEKSWNYELGTRGRIGNGLsAEVALFYIDYDNELGS--------C 511
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 310 APAGGYDReirasntpngsaiyrnytatnvyRWGNTPRAIIEGLEGNITLPFLDDAIL---FSTNFTY----MLKNENKQ 382
Cdd:COG4772   512 SAAGGDRS-----------------------TFTNAGETRHQGLELALDYDLLKGGGLglpLFAAYTYtdaeFTSDFGPV 568
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 383 T-GNPISLVPKYTVNSNLNWKiNDHWDINTSYTRYGKQKTveNAENFMQviytTGESLVnqyhLGSYGSWGANFGYKFND 461
Cdd:COG4772   569 FaGNRLPYVPRHQLTAGLGYE-HGGWTANLNGRYVSEQFT--DAANTVA----DGSFGK----IPSYTVLDLSASYDFGK 637
                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*..
gi 1040783758 462 NLSLRLGVNNILDKRiYrnAGTARTYNERG------RSYFANLKYSF 502
Cdd:COG4772   638 NLSLFAGVNNLFDKR-Y--IASRAPNYAAGirpgppRTVYAGLRLKF 681
TonB-hemlactrns TIGR01786
TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model ...
21-502 5.00e-24

TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model represents a family of TonB-dependent outer membrane receptor/transporters acting on iron-containing proteins such as hemoglobin, transferrin and lactoferrin. Two subfamily models with a narrower scope are contained within this model, the heme/hemoglobin receptor family protein model (TIGR01785) and the transferrin/lactoferrin receptor family model (TIGR01776). Accessions which score above trusted to this model while not scoring above trusted to the more specific models are most likely to be hemoglobin transporters. Nearly all of the species containing trusted hits to this model have access to hemoglobin, transferrin or lactoferrin or related proteins in their biological niche. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273808 [Multi-domain]  Cd Length: 715  Bit Score: 105.96  E-value: 5.00e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758  21 SYSLTHEGKWgsFDNRTYFTFDQT-RNYHYpeglLGSTEGAYNGLNKSVGFLRN----YRFSNELYIPFTLGSTGHMVTI 95
Cdd:TIGR01786 278 DYELNPDNSW--LDTVKLALDKQYiQLYNY----LNATSASDYPGVDKNGRYKDkydyYTLGFDTNNKIEFSVHSLSLTY 351
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758  96 GAEASRSELNdAASMTQTMQVYAIVPwLADKGRSGKVAQNEWAAFLEDNIMLpNNKTILTPGIRFD-------------- 161
Cdd:TIGR01786 352 GLDRFKDKVS-TGDSRRNLPTAAYNL-YGYEGENRPVKGSNFGLFLQDNIKL-GDWLSLSAGLRYDhyktdpkadeskdy 428
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 162 -SSTNSKSNWSPSFNFSHQVSENWKIKGGVARAYKAPNLYQSspnyllvnasngcpidsannwnnpnalnptgsngtrnn 240
Cdd:TIGR01786 429 gAISKTYSRWSPSLGLTYKPTPWLTLYYSYSQGFRAPSFDEL-------------------------------------- 470
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 241 pYTNSNAKGFDwgrACYFLGNENIKPETSWNKEIGFEYENEGKLFSLAYFHNDYRNKIvsngefLTTIDAPAGGYDREIR 320
Cdd:TIGR01786 471 -YGTGAHPGGG---PYTFLPNPNLKPETSKNWEIGINLHFDQLDFKVSYFRNDYKDFI------DLGIGVTAKGNMAQVG 540
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 321 ASNTPNgsaiYRNytATNVYRWGntpraiIEgLEGNI---TLPFLDDAILFSTNFTYMlKNENKQTGNPISLVPKYTVNS 397
Cdd:TIGR01786 541 SNTITN----YVN--IDNARIRG------IE-LSGRYdlgSFFSGPDGWTTTLKYGYT-KGKDSDTNPWLNAITPLKVVL 606
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 398 NLNWKI-NDHWDINTSYTRYGKQKTVENAENFmqviYTTGESLVNQYHL-GSYGSWGANFGYKFNDNLSLRLGVNNILDK 475
Cdd:TIGR01786 607 GLGYDHpDEKWGVGLTLTFSGAKDAVDAYATY----YENGEAAKAGPLRtPSYTVVDLYGYYKPNKNLTLRFGVYNLLDR 682
                         490       500       510
                  ....*....|....*....|....*....|...
gi 1040783758 476 R-----IYRNAGT-ARTYNERGRSYFANLKYSF 502
Cdd:TIGR01786 683 KyttweSARQAGPlATGYTAPGRNYKASVEYKF 715
PRK13486 PRK13486
TonB-dependent receptor;
91-502 1.33e-23

TonB-dependent receptor;


Pssm-ID: 139606 [Multi-domain]  Cd Length: 696  Bit Score: 104.72  E-value: 1.33e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758  91 HMVTIGAEASRSELNDAASMTQTMQVYAivpwladkgrsgkvaQNEWAAFLEDNIMLpNNKTILTPGIRFDSSTNSKSNW 170
Cdd:PRK13486  354 HLVTVGGEFQSSSMKDGVVLASTGETFR---------------QKSWSVFAEDEWHL-TDALALTAGSRYEHHEQFGGHF 417
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 171 SPSFNFSHQVSENWKIKGGVARAYKAPNLYQsspnyllvnasngcpidsannwnnpnalNPTGSNGTRNNPYTNsnakgf 250
Cdd:PRK13486  418 SPRAYLVWDVADAWTLKGGVTTGYKAPRMGQ----------------------------LHKGISGVSGQGKTN------ 463
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 251 dwgracyFLGNENIKPETSWNKEIGFEYENEGKL-FSLAYFHNDYRNKIVSngeflTTIDapaggydreiraSNTpngsa 329
Cdd:PRK13486  464 -------LLGNPDLKPEESVSYEAGVYYDNPAGLnANVTGFMTDFSNKIVS-----YSIN------------DNT----- 514
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 330 iyRNYTatnvyrwgNTPRAIIEGLEGNITLPFLDDAILFSTNFTYML--KNENKQTGNPISLVPKYTVNSNLNWKINDhw 407
Cdd:PRK13486  515 --NSYV--------NSGKARLHGVEFAGTLPLWSEDVTLSLNYTWTRseQRDGDNKGAPLSYTPEHMVNAKLNWQITE-- 582
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 408 DINTSYTRYGKQKTVENAENF------MQVIY-TTGEslvnqyHLGSYGSWGANFGYKFNDNLSLRLGVNNILDK----- 475
Cdd:PRK13486  583 EVASWLGARYRGKTPRFTQNYsslsavQKKVYdEKGE------YLKAWTVVDAGLSWKMTDALTLNAAVNNLLNKdysdv 656
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|.
gi 1040783758 476 RIYRnAGTARTYNER--------------GRSYFANLKYSF 502
Cdd:PRK13486  657 SLYS-AGKSTLYAGDyfqtgssttgyvipERNYWMSLNYQF 696
PRK13484 PRK13484
IreA family TonB-dependent siderophore receptor;
91-502 3.11e-23

IreA family TonB-dependent siderophore receptor;


Pssm-ID: 139605 [Multi-domain]  Cd Length: 682  Bit Score: 103.55  E-value: 3.11e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758  91 HMVTIGAEASRSELNDAASMTQTmqvyaivpwladKGRSGKVAQNEWAAFLEDNIMLPNNKTiLTPGIRFDSSTNSKSNW 170
Cdd:PRK13484  351 NVLTIGGQFQHAELRDDSATGKK------------TTETQSVSIKQKAVFIENEYAATDSLA-LTGGLRLDNHEIYGSYW 417
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 171 SPSFNFSHQVSENWKIKGGVARAYKAPNLYQSSPNYllvnasngcpidsannwnnpnalnptgsnGTrnnpytnSNAKGf 250
Cdd:PRK13484  418 NPRLYAVYNLTDNLTLKGGIAKAFRAPSIREVSPGF-----------------------------GT-------LTQGG- 460
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 251 dwgrACYFLGNENIKPETSWNKEIGFEYEN-EGKLFSLAYFHNDYRNKIVSNGefLTTIDApaggydreirasntpngsa 329
Cdd:PRK13484  461 ----ASIMYGNRDLKPETSVTEEIGIIYSNdSGFSASATLFNTDFKNKLTSYD--IGTKDP------------------- 515
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 330 iyrnYTATNVYRWGNTPRAIIEGLEGNITLPFLDDAILfSTNFTYM---LKNENKQ------TGNPISLVPKYTVNSNLN 400
Cdd:PRK13484  516 ----VTGLNTFIYDNVGEANIRGVELATQIPVYDKWHV-SANYTFTdsrRKSDDESlngkslKGEPLERTPRHAANAKLE 590
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 401 WKINDHWDI--NTSYTryGKQKTVENAENFMQVIYTTGeslvnqyhlgsYGSWGANFGYKFNDNLSLRLGVNNILDKR-- 476
Cdd:PRK13484  591 WDYTQDITFysSLNYT--GKQIWAAQRNGAKVPRVRNG-----------FTSMDIGLNYQILPDTLINFAVLNVTDRKse 657
                         410       420
                  ....*....|....*....|....*..
gi 1040783758 477 -IYRNAGTARTynERGRSYFANLKYSF 502
Cdd:PRK13484  658 dIDTIDGNWQV--DEGRRYWANVRVSF 682
TonB-siderophor TIGR01783
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ...
14-502 5.05e-20

TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273805 [Multi-domain]  Cd Length: 651  Bit Score: 93.25  E-value: 5.05e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758  14 TSTLYRQSYSLTHEGKWgsfdNRTYFTFDQTRNYHYPEGLLGSTEGAYNGLNKSVGFLRNYRFSNELYIPFTLGSTGHMV 93
Cdd:TIGR01783 235 YGLSLEYQFNDVWTGKQ----NLRYSYFDTDSNQVQASGYSSDGGLFGRSLTVVNVKQDRVQIDAGLDGEFETGPIEHDL 310
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758  94 TIGAEASRSELNDAASMTQ-TMQVYAIVPWL--------ADKGRSGKVAQNEWAAFLEDNIMLpNNKTILTPGIRFDSst 164
Cdd:TIGR01783 311 LLGVSYGQRTTNRFNNTGYpSDNIYSLTATSsartdigdSPKDRALSSTTKALNGVALQRILL-ADKWTLTLGGRYDS-- 387
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 165 NSKSNWSPSFNFSHQVSENWkIKGGVARAYKAPNLYQSSPNYLLVNASNGCpidsannwnnpnalnptgsngtrnnpytn 244
Cdd:TIGR01783 388 VDVKSNNGVAGSTGKRDDSQ-FTPSLGVAYKPTDDWSLYASYAESFKPGGY----------------------------- 437
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 245 sNAKGFDWGracyflgNENIKPETSWNKEIGFEYENEGK-LFSLAYFHNDYRNKIVSNgeflttidapaggydreirasn 323
Cdd:TIGR01783 438 -YPKGAGNS-------GDILEPEKGKNYELGVRYDLGDSlLATAALFRITKDNQLVQD---------------------- 487
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 324 tPNGSAIYRNYTATNVYrwgntpraiieGLEGNITLPFLDD-AILFSTNFTYM---LKNENKQTGNPISLVPKYTVNSNL 399
Cdd:TIGR01783 488 -PVNGTFSVNAGKTRNR-----------GVELEARGYLTPGlSLSAGYTYTDAeftEDTNGDTQGNTVPFVPKHTASLWA 555
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 400 NWKINDhWDINTSYTRYGKQKTVENAENFmqviyttgeslvNQYHLGSYGSWGANFGYKF--NDNLSLRLGVNNILDKRI 477
Cdd:TIGR01783 556 SYAPPV-GDNGLTLGGGVQYTGKAYVDGG------------NTGKVPSYTVVDLSVRYDLtkKKNLTLALNVNNLFDRDY 622
                         490       500
                  ....*....|....*....|....*....
gi 1040783758 478 Y----RNAGTARTYNERGRSYFANLKYSF 502
Cdd:TIGR01783 623 YtsgyRWGPSAYIYPGAPRTVGLSVSYDF 651
TonB-hemin TIGR01785
TonB-dependent heme/hemoglobin receptor family protein; This model represents the ...
131-502 7.22e-20

TonB-dependent heme/hemoglobin receptor family protein; This model represents the TonB-dependent outer membrane heme/hemoglobin receptor/transporter found in bacteria which live in contact with animals (which contain hemoglobin or other heme-bearing globins) or legumes (which contain leghemoglobin). Some species having hits to this model such as Nostoc, Caulobacter and Chlorobium do not have an obvious source of hemoglobin-like proteins in their biological niche and so the possibility exists that they act on some other substance. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273807 [Multi-domain]  Cd Length: 665  Bit Score: 92.84  E-value: 7.22e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 131 KVAQNEWAAFLEDNIMLPNNKTILTPGIRFDS-STNSKSN------------WSPSFNFSHQVSENWKIKGGVARAYKAP 197
Cdd:TIGR01785 350 SAKEYFFGLFLQDNIPLLDDRLTLSAGLRYDHyKLSPKTTadteavdrsysrWSPSLGLSYKPVDWLTLYASYSQGFRAP 429
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 198 NLYQSspnyllvnasngcpidsannwnnpnalnptgsngtrnnpYTNSNAKGFdwGRACYFLGNENIKPETSWNKEIGFE 277
Cdd:TIGR01785 430 SIDEL---------------------------------------YGTGDHPGT--PGGYTFAPNPNLKPETSKTWELGAN 468
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 278 YENEGKLFS-------LAYFHNDYRNKIvsngefLTTIDAPAGGYDReirasntpngsaiyrnytATNVYRWGNTPRAII 350
Cdd:TIGR01785 469 LSFDNLLLDndqlqfkVAYFYNDVKDFI------DLTIGVTDNVTAG------------------MNNITQYVNIDGARI 524
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 351 EGLEGNITLpfldDAILFSTNFTYM-LKNENKQTGNPISLVPKYTVNSNLNWKI-NDHWDIN---TSYTRYGKQKTVENA 425
Cdd:TIGR01785 525 RGIEASASY----DAGLWATGLSYGyTIGKDQNTNQWLSNIPPLKLVVTVGYRFpDRRLDLGakaAYYERQSESPTTEDV 600
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1040783758 426 ENFMQVIYTtgeslvnqyhlgSYGSWGANFGYKFND--NLSLRLGVNNILDKRIYRNAGTArtYNERGRSYFANLKYSF 502
Cdd:TIGR01785 601 AANGLLTTP------------GYTVVDLYATYQPNAvkGLTVRFGVNNLTDRKYTPAQSVP--GAGPGRNFKGSVKYQF 665
FhuE COG4773
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ...
21-502 1.65e-17

Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];


Pssm-ID: 443805 [Multi-domain]  Cd Length: 692  Bit Score: 85.72  E-value: 1.65e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758  21 SYSLTHE-GKWGSFDNR-TYFTFDQTRNYHYPEGLLGSTEGAYN-GLNKSVGFLRNYRFSNELYIPFTLGSTGHMVTIGA 97
Cdd:COG4773   289 FAELEHRfNDDWSLRANaRYSDSDRDGRSAYAYGAPDAATGTLTrYASARDGDSRSDSLDANLNGKFETGGLEHTLLVGA 368
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758  98 EASRSELNDAASMTQTM----QVYAIVPWLADKGRSGKVAQNEWAAFLEDNIMLpNNKTILTPGIRFD------------ 161
Cdd:COG4773   369 DYSRYDSDSDSATAGTIniynPVYGNLPEPDFDASDTDTTTRQTGLYAQDQISL-TDRLSLLLGGRYDwyetdstnrlgg 447
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 162 -SSTNSKSNWSPSFNFSHQVSENWkikggvaraykapNLYQSspnYllvnasngcpidsannwnnpnalnptgSNGTRNN 240
Cdd:COG4773   448 sTTSYDDSAFTPRAGLVYDLTPGL-------------SLYAS---Y---------------------------SESFEPQ 484
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 241 PYTNSNakgfdwgracyflgNENIKPETSWNKEIGFEYE-NEGKL-FSLAYFHNDYRNkivsngeflttidapaggydre 318
Cdd:COG4773   485 SGADNN--------------GNPLDPETGKQYEAGVKGElFDGRLnATLAVFDITQKN---------------------- 528
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 319 iRASNTPNGSAIYRnytatnvyrwgNTPRAIIEGLE----GNITlpfldDAILFSTNFTYM----LKNENKQTGNPISLV 390
Cdd:COG4773   529 -VATTDPDNPNFYV-----------QVGEVRSRGVElelsGELT-----PGLNLIAGYTYTdakiTKDADALEGKRLTNV 591
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 391 PKYTVNSNLNWKIND----HWDINTSYTRYGKQKTvenaenfmqviyttgeSLVNQYHLGSYGSWGANFGYKFNDNLSLR 466
Cdd:COG4773   592 PRHTASLWTTYRFPSgalkGLGLGGGVRYVGERYG----------------DAANTFTLPSYTLVDAGARYDLGKNWTLQ 655
                         490       500       510
                  ....*....|....*....|....*....|....*...
gi 1040783758 467 LGVNNILDKRIYRNAGTaRTYNERG--RSYFANLKYSF 502
Cdd:COG4773   656 LNVNNLFDKKYYASSGS-RGYVYYGapRNVRLSLSYKF 692
Fiu COG4774
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
21-502 1.51e-14

Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];


Pssm-ID: 443806 [Multi-domain]  Cd Length: 639  Bit Score: 76.07  E-value: 1.51e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758  21 SYSLTHE-GKWGSFDNRT-YFTFDQTRNYHYPEGLLGSTEGAYNGLNKSVgflRNYRFSNELYI--PFTLGSTGHMVTIG 96
Cdd:COG4774   231 TLRLEHDfNDNWTLRNALrYSDYDRDYRNTYPTGGNATGTVTRSAYRRDQ---DNDTLSNQTDLtgKFDTGGVKHTLLAG 307
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758  97 AEASRSElNDAASMTQTMQVYAI--------VPWLAD--KGRSGKVAQNEWAAFLEDNIMLpNNKTILTPGIRFDSSTNS 166
Cdd:COG4774   308 VEYSRED-SDNARYSGGGTAPTVnlynpvygAPVTGPtlGGADNDSRTDTTGLYLQDTISL-TDRWSLLAGLRYDRFDTD 385
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 167 KSNWSPSFNFSHQVSENWKIKGGVaraykapnLYQSSPNYLL-VNASNGcpidsannwnnpnaLNPTGSNGTRNNpytns 245
Cdd:COG4774   386 YTDRTTGATTSSYDDSAFSPRAGL--------VYKPTPNLSLyASYSTS--------------FNPGGGAPSLSN----- 438
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 246 nakgfdwgracyflGNENIKPETSWNKEIGFEYE-NEGKL-FSLAYFHNDYRNKIVSNgeflttidapaggydreirasn 323
Cdd:COG4774   439 --------------AGQALDPEKSRQYEVGVKWDlLDGRLsLTAALFRIEKTNVRTTD---------------------- 482
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 324 tPNGSAIYRNYTATNVyrwgntpraiiEGLE----GNITlpfldDAILFSTNFTYM----LKNENKQT-GNPISLVPKYT 394
Cdd:COG4774   483 -PANPGVYVQTGEQRS-----------RGVEleatGELT-----PGWSVLAGYTYLdaeiTKSANAANvGNRLPNVPRHS 545
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040783758 395 VNSNLNWKIN-DHWDINTSYTRYGKQKTvenaenfmqviyttgeSLVNQYHLGSYGSWGANFGYKFNDNLSLRLGVNNIL 473
Cdd:COG4774   546 ASLWTTYDLPlPGLTLGGGVRYVGSRYA----------------DAANTVKLPSYTRFDAGASYRLNKNLTLRLNVNNLT 609
                         490       500       510
                  ....*....|....*....|....*....|
gi 1040783758 474 DKRIYRNA-GTARTYNERGRSYFANLKYSF 502
Cdd:COG4774   610 DKRYYASAyGSGYVTPGAPRTVLLSASYRF 639
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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