|
Name |
Accession |
Description |
Interval |
E-value |
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
109-455 |
4.57e-20 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 93.84 E-value: 4.57e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 109 FNLQNLTVLLLENNQLNKIPSNLPGSLRNLNLIQNNIISVTKHSTSGLKNLERLNLGWNcyfgnvcnqsfrvdGAFEEIP 188
Cdd:COG4886 48 LLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGN--------------EELSNLT 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 189 NLKVLILSFNNLSRVPPNLPR--SLTELYLSNTNIHSIGSrDFEKLENLTVLDLSGNcprcfnapfpctpcakdaSIKID 266
Cdd:COG4886 114 NLESLDLSGNQLTDLPEELANltNLKELDLSNNQLTDLPE-PLGNLTNLKSLDLSNN------------------QLTDL 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 267 DHAFQKLSKLQYLNLSSTSLQVIREiWFDNMSSLKELHLEFNYLvHEIASGnfLTKLPHLEILDLSYNYVKTQyalylnl 346
Cdd:COG4886 175 PEELGNLTNLKELDLSNNQITDLPE-PLGNLTNLEELDLSGNQL-TDLPEP--LANLTNLETLDLSNNQLTDL------- 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 347 sPNFSNLTSLRTLHLRGyvfqeLRYEDFKPLMKLSNLTTINLGVNFIKQINFSVFQHLPNLNVIYLSENRISPLVNDIRQ 426
Cdd:COG4886 244 -PELGNLTNLEELDLSN-----NQLTDLPPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILL 317
|
330 340
....*....|....*....|....*....
gi 1052247133 427 SSANFSTVQSHVLKPRSADNEFDPHSNFY 455
Cdd:COG4886 318 LLLTTLLLLLLLLKGLLVTLTTLALSLSL 346
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
446-759 |
4.25e-19 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 91.15 E-value: 4.25e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 446 NEFDPHSNFYHNTHPLMKQKCTRYGKAIDLSLNSIFFIGQKQFEAFPNISCLNLSSNGNAQALNGSEFSAVPHIKYLDLT 525
Cdd:COG4886 1 LLLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 526 HNKLDFDYDTALNELRELEVLDLSYNEHyfriagvthrlgfIKNLTKLDFLNLSHNDIYTLTEYNLSSESLTTLDFSGNR 605
Cdd:COG4886 81 LLSLLLLGLTDLGDLTNLTELDLSGNEE-------------LSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQ 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 606 LDVLWHAedkrytyiFRNLNNLTWLDLSFNNLQQIPSkAFINLPrNLTHLFINDNKLSFFNWTlLETFSHLKLLDLSGNC 685
Cdd:COG4886 148 LTDLPEP--------LGNLTNLKSLDLSNNQLTDLPE-ELGNLT-NLKELDLSNNQITDLPEP-LGNLTNLEELDLSGNQ 216
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1052247133 686 LYFLTDKLAKFaKSLKELILSRNHISHLP-LGFLPEdsgLVHLDLSSNKLKTINRSTfpeKNTTLALLELHGNPF 759
Cdd:COG4886 217 LTDLPEPLANL-TNLETLDLSNNQLTDLPeLGNLTN---LEELDLSNNQLTDLPPLA---NLTNLKTLDLSNNQL 284
|
|
| TIR |
smart00255 |
Toll - interleukin 1 - resistance; |
865-1001 |
7.87e-16 |
|
Toll - interleukin 1 - resistance;
Pssm-ID: 214587 [Multi-domain] Cd Length: 140 Bit Score: 75.44 E-value: 7.87e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 865 YDAYVSYdtkdaSVTDWVINELRSHLEESEDKNVLlCLEERDWDPGLAIIDNLMQSINQSKKTIFVLTSKYARSWSFKTA 944
Cdd:smart00255 2 YDVFISY-----SGKEDVRNEFLSHLLEKLRGYGL-CVFIDDFEPGGGDLEEIDEAIEKSRIAIVVLSPNYAESEWCLDE 75
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1052247133 945 FYLALQRLMDENMDVIVFILLEP----VLQHSQYLRLRQRIcksSILQWPDNPKAEglFWQ 1001
Cdd:smart00255 76 LVAALENALEEGGLRVIPIFYEVipsdVRKQPGKFRKVFKK---NYLKWPEDEKEQ--FWK 131
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
169-663 |
9.99e-13 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 72.57 E-value: 9.99e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 169 YFGNVCNQSFRVDG--------------AFEEIPNLKVLILSFNNLS-RVPPN---LPRSLTELYLSNTNIHSIGSRDFe 230
Cdd:PLN00113 60 WQGITCNNSSRVVSidlsgknisgkissAIFRLPYIQTINLSNNQLSgPIPDDiftTSSSLRYLNLSNNNFTGSIPRGS- 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 231 kLENLTVLDLSGNCprcFNAPFPcTPCAKDASIKIDD-----------HAFQKLSKLQYLNLSSTSL--QVIREIwfDNM 297
Cdd:PLN00113 139 -IPNLETLDLSNNM---LSGEIP-NDIGSFSSLKVLDlggnvlvgkipNSLTNLTSLEFLTLASNQLvgQIPREL--GQM 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 298 SSLKELHLEFNYLVHEIAsgNFLTKLPHLEILDLSYNYVKTQyalylnLSPNFSNLTSLRTLHLrgyvFQELRYEDFKP- 376
Cdd:PLN00113 212 KSLKWIYLGYNNLSGEIP--YEIGGLTSLNHLDLVYNNLTGP------IPSSLGNLKNLQYLFL----YQNKLSGPIPPs 279
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 377 LMKLSNLTTINLGVNFIK-QINFSVFQhLPNLNVIYLSENRIS----------PLVNDIRQSSANFSTVQSHVLKPRSAD 445
Cdd:PLN00113 280 IFSLQKLISLDLSDNSLSgEIPELVIQ-LQNLEILHLFSNNFTgkipvaltslPRLQVLQLWSNKFSGEIPKNLGKHNNL 358
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 446 NEFDPHSNfyHNTHPLMKQKCTRyGKAIDLSLNSIFFIGQ--KQFEAFPNISCLNLSSNGNAQALNgSEFSAVPHIKYLD 523
Cdd:PLN00113 359 TVLDLSTN--NLTGEIPEGLCSS-GNLFKLILFSNSLEGEipKSLGACRSLRRVRLQDNSFSGELP-SEFTKLPLVYFLD 434
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 524 LTHNKLDFDYDTALNELRELEVLDLSYNehyfRIAGVTHRLGFIKNLTKLDflnLSHNDIYTLTEYNLSSES-LTTLDFS 602
Cdd:PLN00113 435 ISNNNLQGRINSRKWDMPSLQMLSLARN----KFFGGLPDSFGSKRLENLD---LSRNQFSGAVPRKLGSLSeLMQLKLS 507
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1052247133 603 GNRLDVLWHAEdkrytyiFRNLNNLTWLDLSFNNLQ-QIPSkAFINLPRnLTHLFINDNKLS 663
Cdd:PLN00113 508 ENKLSGEIPDE-------LSSCKKLVSLDLSHNQLSgQIPA-SFSEMPV-LSQLDLSQNQLS 560
|
|
| TIR |
pfam01582 |
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular ... |
865-1009 |
4.50e-09 |
|
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular signalling domain found in MyD88, interleukin 1 receptor and the Toll receptor. It contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. TIR-like motifs are also found in plant proteins thought to be involved in resistance to disease. When activated, TIR domains recruit cytoplasmic adaptor proteins MyD88 and TOLLIP (Toll interacting protein). In turn, these associate with various kinases to set off signalling cascades.
Pssm-ID: 396246 [Multi-domain] Cd Length: 165 Bit Score: 56.60 E-value: 4.50e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 865 YDAYVSYDTKDasVTDWVINELRSHLEEsedKNVLLCLEERDWDPGLAIIDNLMQSINQSKKTIFVLTSKYARS-WS--- 940
Cdd:pfam01582 1 YDVFLSFRGSD--TREWFVSHLLKELKQ---KGIKLFIDDRDLEPGEAIAPELLSAIEKSRRSVVVLSPNYASSgWClde 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 941 FKTAFYLALQRlmdeNMDVI--------------------VFILLEPVLQHSQYLRLRQRICKSSILQWPDNPKAEGLFW 1000
Cdd:pfam01582 76 LVKILECALDL----GQKVIpifyevdpsdvrkqtgsfgkAFKKHKKVLTEEKVLKWRGALNEVANIWHSKSVSDESKFW 151
|
....*....
gi 1052247133 1001 QSLKNVVLT 1009
Cdd:pfam01582 152 KKIAYDISN 160
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
524-759 |
1.33e-08 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 56.33 E-value: 1.33e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 524 LTH---NKLDFDYDTALNELRELEVLDLsYNEHYFRIAGvthrLGFIKNLTKLDflnLSHNDIYTLTeyNLSS-ESLTTL 599
Cdd:cd21340 4 ITHlylNDKNITKIDNLSLCKNLKVLYL-YDNKITKIEN----LEFLTNLTHLY---LQNNQIEKIE--NLENlVNLKKL 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 600 DFSGNRLDVLwhaedkrytyifRNLNNLTwldlsfnnlqqipskafinlprNLTHLFINDNKLSffnwtlletfshlkll 679
Cdd:cd21340 74 YLGGNRISVV------------EGLENLT----------------------NLEELHIENQRLP---------------- 103
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 680 dlSGNCLYFLTDKLAKFAKSLKELILSRNHISHL-PLGFLpedSGLVHLDLSSNKLKTINRSTFPEKN-TTLALLELHGN 757
Cdd:cd21340 104 --PGEKLTFDPRSLAALSNSLRVLNISGNNIDSLePLAPL---RNLEQLDASNNQISDLEELLDLLSSwPSLRELDLTGN 178
|
..
gi 1052247133 758 PF 759
Cdd:cd21340 179 PV 180
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
95-243 |
3.16e-08 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 55.18 E-value: 3.16e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 95 HINKEGMNITD-GAFFNLQNLTVLLLENNQLNKIPsNLpGSLRNL-NL-IQNNIISVTKHsTSGLKNLERLNLGWNC--- 168
Cdd:cd21340 6 HLYLNDKNITKiDNLSLCKNLKVLYLYDNKITKIE-NL-EFLTNLtHLyLQNNQIEKIEN-LENLVNLKKLYLGGNRisv 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 169 -------------YFGNVCNQS-----FRVDGAFEEIPNLKVLILSFNNLSRVPP--NLpRSLTELYLSNTNIHSIG--S 226
Cdd:cd21340 83 veglenltnleelHIENQRLPPgekltFDPRSLAALSNSLRVLNISGNNIDSLEPlaPL-RNLEQLDASNNQISDLEelL 161
|
170
....*....|....*..
gi 1052247133 227 RDFEKLENLTVLDLSGN 243
Cdd:cd21340 162 DLLSSWPSLRELDLTGN 178
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
264-310 |
1.58e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 49.06 E-value: 1.58e-07
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 1052247133 264 KIDDHAFQKLSKLQYLNLSSTSLQVIREIWFDNMSSLKELHLEFNYL 310
Cdd:pfam13855 15 SLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
573-734 |
4.36e-07 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 53.93 E-value: 4.36e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 573 LDFLNLSHNDIYTLTEYnLSSeSLTTLDFSGNRLDVLWHaedkrytyifrNL-NNLTWLDLSFNNLQQIPSkafiNLPRN 651
Cdd:PRK15370 243 IQEMELSINRITELPER-LPS-ALQSLDLFHNKISCLPE-----------NLpEELRYLSVYDNSIRTLPA----HLPSG 305
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 652 LTHLFINDNKLSFFNWTLLetfSHLKLLDLSGNCLYFLTDKLakfAKSLKELILSRNHISHLPLGFLPEdsgLVHLDLSS 731
Cdd:PRK15370 306 ITHLNVQSNSLTALPETLP---PGLKTLEAGENALTSLPASL---PPELQVLDVSKNQITVLPETLPPT---ITTLDVSR 376
|
...
gi 1052247133 732 NKL 734
Cdd:PRK15370 377 NAL 379
|
|
| PCC |
TIGR00864 |
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) ... |
728-810 |
1.32e-06 |
|
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) Polycystin is a huge protein of 4303aas. Its repeated leucine-rich (LRR) segment is found in many proteins. It contains 16 polycystic kidney disease (PKD) domains, one LDL-receptor class A domain, one C-type lectin family domain, and 16-18 putative TMSs in positions between residues 2200 and 4100. Polycystin-L has been shown to be a cation (Na+, K+ and Ca2+) channel that is activated by Ca2+. Two members of the PCC family (polycystin 1 and 2) are mutated in autosomal dominant polycystic kidney disease, and polycystin-L is deleted in mice with renal and retinal defects. Note: this model is restricted to the amino half.
Pssm-ID: 188093 [Multi-domain] Cd Length: 2740 Bit Score: 52.78 E-value: 1.32e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 728 DLSSNKLKTINRSTFpEKNTTLALLELHGNPFDCTCDMGDFRSWMdKHQNVTIPRLTDVLCASPGDQIGKSIMSLELTTC 807
Cdd:TIGR00864 1 DISNNKISTIEEGIC-ANLCNLSEIDLSGNPFECDCGLARLPRWA-EEKGVKVRQPEAALCAGPGALAGQPLLGIPLLDS 78
|
...
gi 1052247133 808 VSD 810
Cdd:TIGR00864 79 GCD 81
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
595-662 |
3.79e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 45.21 E-value: 3.79e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1052247133 595 SLTTLDFSGNRLDVLwhaEDKrytyIFRNLNNLTWLDLSFNNLQQIPSKAFINLPrNLTHLFINDNKL 662
Cdd:pfam13855 2 NLRSLDLSNNRLTSL---DDG----AFKGLSNLKVLDLSNNLLTTLSPGAFSGLP-SLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
52-124 |
1.27e-05 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 43.67 E-value: 1.27e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1052247133 52 VTELDLSDNLIKHITNESFQGLQALTKINLNCNVMlppysknDHINkegmnitDGAFFNLQNLTVLLLENNQL 124
Cdd:pfam13855 3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLL-------TTLS-------PGAFSGLPSLRYLDLSGNRL 61
|
|
| LRRCT |
smart00082 |
Leucine rich repeat C-terminal domain; |
757-797 |
1.02e-04 |
|
Leucine rich repeat C-terminal domain;
Pssm-ID: 214507 [Multi-domain] Cd Length: 51 Bit Score: 40.88 E-value: 1.02e-04
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 1052247133 757 NPFDCTCDMGDFRSWmdKHQNVTIPRLTDVLCASPGDQIGK 797
Cdd:smart00082 1 NPFICDCELRWLLRW--LQANEHLQDPVDLRCASPSSLRGP 39
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
109-455 |
4.57e-20 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 93.84 E-value: 4.57e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 109 FNLQNLTVLLLENNQLNKIPSNLPGSLRNLNLIQNNIISVTKHSTSGLKNLERLNLGWNcyfgnvcnqsfrvdGAFEEIP 188
Cdd:COG4886 48 LLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGN--------------EELSNLT 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 189 NLKVLILSFNNLSRVPPNLPR--SLTELYLSNTNIHSIGSrDFEKLENLTVLDLSGNcprcfnapfpctpcakdaSIKID 266
Cdd:COG4886 114 NLESLDLSGNQLTDLPEELANltNLKELDLSNNQLTDLPE-PLGNLTNLKSLDLSNN------------------QLTDL 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 267 DHAFQKLSKLQYLNLSSTSLQVIREiWFDNMSSLKELHLEFNYLvHEIASGnfLTKLPHLEILDLSYNYVKTQyalylnl 346
Cdd:COG4886 175 PEELGNLTNLKELDLSNNQITDLPE-PLGNLTNLEELDLSGNQL-TDLPEP--LANLTNLETLDLSNNQLTDL------- 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 347 sPNFSNLTSLRTLHLRGyvfqeLRYEDFKPLMKLSNLTTINLGVNFIKQINFSVFQHLPNLNVIYLSENRISPLVNDIRQ 426
Cdd:COG4886 244 -PELGNLTNLEELDLSN-----NQLTDLPPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILL 317
|
330 340
....*....|....*....|....*....
gi 1052247133 427 SSANFSTVQSHVLKPRSADNEFDPHSNFY 455
Cdd:COG4886 318 LLLTTLLLLLLLLKGLLVTLTTLALSLSL 346
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
446-759 |
4.25e-19 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 91.15 E-value: 4.25e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 446 NEFDPHSNFYHNTHPLMKQKCTRYGKAIDLSLNSIFFIGQKQFEAFPNISCLNLSSNGNAQALNGSEFSAVPHIKYLDLT 525
Cdd:COG4886 1 LLLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 526 HNKLDFDYDTALNELRELEVLDLSYNEHyfriagvthrlgfIKNLTKLDFLNLSHNDIYTLTEYNLSSESLTTLDFSGNR 605
Cdd:COG4886 81 LLSLLLLGLTDLGDLTNLTELDLSGNEE-------------LSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQ 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 606 LDVLWHAedkrytyiFRNLNNLTWLDLSFNNLQQIPSkAFINLPrNLTHLFINDNKLSFFNWTlLETFSHLKLLDLSGNC 685
Cdd:COG4886 148 LTDLPEP--------LGNLTNLKSLDLSNNQLTDLPE-ELGNLT-NLKELDLSNNQITDLPEP-LGNLTNLEELDLSGNQ 216
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1052247133 686 LYFLTDKLAKFaKSLKELILSRNHISHLP-LGFLPEdsgLVHLDLSSNKLKTINRSTfpeKNTTLALLELHGNPF 759
Cdd:COG4886 217 LTDLPEPLANL-TNLETLDLSNNQLTDLPeLGNLTN---LEELDLSNNQLTDLPPLA---NLTNLKTLDLSNNQL 284
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
471-758 |
6.44e-19 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 90.38 E-value: 6.44e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 471 KAIDLSLNSIFFIGQKQFEAFPNISCLNLSSNgnaqalngSEFSAVPHIKYLDLTHNKLDfDYDTALNELRELEVLDLSY 550
Cdd:COG4886 75 LLLSLLLLSLLLLGLTDLGDLTNLTELDLSGN--------EELSNLTNLESLDLSGNQLT-DLPEELANLTNLKELDLSN 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 551 NEhyfriagVTHRLGFIKNLTKLDFLNLSHNDIYTLTEYNLSSESLTTLDFSGNRLDVLwhaedkryTYIFRNLNNLTWL 630
Cdd:COG4886 146 NQ-------LTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQITDL--------PEPLGNLTNLEEL 210
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 631 DLSFNNLQQIPSkAFINLPrNLTHLFINDNKLSFFNWtlLETFSHLKLLDLSGNCLYFLTDklAKFAKSLKELILSRNHI 710
Cdd:COG4886 211 DLSGNQLTDLPE-PLANLT-NLETLDLSNNQLTDLPE--LGNLTNLEELDLSNNQLTDLPP--LANLTNLKTLDLSNNQL 284
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 1052247133 711 SHLPLGFLPEDSGLVHLDLSSNKLKTINRSTFPEKNTTLALLELHGNP 758
Cdd:COG4886 285 TDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKG 332
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
102-420 |
3.35e-17 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 85.37 E-value: 3.35e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 102 NITDGAFFNLQNLTVLLLENNQLNKIPSNLPGSLRNLNLIQNNIISVTKHSTSGLKNLERLNLGWNCYFGNVCNQSFRVD 181
Cdd:COG4886 10 LKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGL 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 182 GAFEEIPNLKVLILSFNNLSRVPPNlprsLTELYLSNTNIHSIGSrDFEKLENLTVLDLSGNcprcfnapfpctpcakda 261
Cdd:COG4886 90 TDLGDLTNLTELDLSGNEELSNLTN----LESLDLSGNQLTDLPE-ELANLTNLKELDLSNN------------------ 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 262 SIKIDDHAFQKLSKLQYLNLSSTSLQVIREiWFDNMSSLKELHLEFNYLvHEIasGNFLTKLPHLEILDLSYNYVKtqya 341
Cdd:COG4886 147 QLTDLPEPLGNLTNLKSLDLSNNQLTDLPE-ELGNLTNLKELDLSNNQI-TDL--PEPLGNLTNLEELDLSGNQLT---- 218
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1052247133 342 lylNLSPNFSNLTSLRTLHLRGyvfQELryEDFKPLMKLSNLTTINLGVNFIKQINFSvfQHLPNLNVIYLSENRISPL 420
Cdd:COG4886 219 ---DLPEPLANLTNLETLDLSN---NQL--TDLPELGNLTNLEELDLSNNQLTDLPPL--ANLTNLKTLDLSNNQLTDL 287
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
52-429 |
1.96e-16 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 83.06 E-value: 1.96e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 52 VTELDLSDNLIKHITNESFQGLQALTKINLNCNVMLPPYSKNDHINKEGMNITD--GAFFNLQNLTVLLLENNQLNKIPS 129
Cdd:COG4886 74 LLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNEELSNLTNLESLDLSGNQLTDlpEELANLTNLKELDLSNNQLTDLPE 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 130 NLpgslrnlnliqnniisvtkhstSGLKNLERLNLGWncyfgnvcNQSFRVDGAFEEIPNLKVLILSFNNLSRVPPNL-- 207
Cdd:COG4886 154 PL----------------------GNLTNLKSLDLSN--------NQLTDLPEELGNLTNLKELDLSNNQITDLPEPLgn 203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 208 PRSLTELYLSNTNIHSIgSRDFEKLENLTVLDLSGNcprcfnapfpctpcakdasiKIDD-HAFQKLSKLQYLNLSSTSL 286
Cdd:COG4886 204 LTNLEELDLSGNQLTDL-PEPLANLTNLETLDLSNN--------------------QLTDlPELGNLTNLEELDLSNNQL 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 287 QVIREIwfDNMSSLKELHLefnylvheiaSGNFLTKLPHLEILDLSYNYVKTQYALYLNLSPNFSNLTSLRTLHLRGYVF 366
Cdd:COG4886 263 TDLPPL--ANLTNLKTLDL----------SNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLL 330
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1052247133 367 QELRYEDFKPLMKLSNLTTINLGVNFIKQINFSVFQHLPNLNVIYLSENRISPLVNDIRQSSA 429
Cdd:COG4886 331 KGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLL 393
|
|
| TIR |
smart00255 |
Toll - interleukin 1 - resistance; |
865-1001 |
7.87e-16 |
|
Toll - interleukin 1 - resistance;
Pssm-ID: 214587 [Multi-domain] Cd Length: 140 Bit Score: 75.44 E-value: 7.87e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 865 YDAYVSYdtkdaSVTDWVINELRSHLEESEDKNVLlCLEERDWDPGLAIIDNLMQSINQSKKTIFVLTSKYARSWSFKTA 944
Cdd:smart00255 2 YDVFISY-----SGKEDVRNEFLSHLLEKLRGYGL-CVFIDDFEPGGGDLEEIDEAIEKSRIAIVVLSPNYAESEWCLDE 75
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1052247133 945 FYLALQRLMDENMDVIVFILLEP----VLQHSQYLRLRQRIcksSILQWPDNPKAEglFWQ 1001
Cdd:smart00255 76 LVAALENALEEGGLRVIPIFYEVipsdVRKQPGKFRKVFKK---NYLKWPEDEKEQ--FWK 131
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
50-243 |
2.05e-13 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 73.43 E-value: 2.05e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 50 KDVTELDLSDNLIKHITnESFQGLQALTKINLNCNvmlppyskndhinkegmNITD--GAFFNLQNLTVLLLENNQLNKI 127
Cdd:COG4886 113 TNLESLDLSGNQLTDLP-EELANLTNLKELDLSNN-----------------QLTDlpEPLGNLTNLKSLDLSNNQLTDL 174
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 128 PSNLPG--SLRNLNLiQNNIISVTKHSTSGLKNLERLNLGwncyfgnvCNQSFRVDGAFEEIPNLKVLILSFNNLSRVPP 205
Cdd:COG4886 175 PEELGNltNLKELDL-SNNQITDLPEPLGNLTNLEELDLS--------GNQLTDLPEPLANLTNLETLDLSNNQLTDLPE 245
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 1052247133 206 --NLPrSLTELYLSNTNIHSIGsrDFEKLENLTVLDLSGN 243
Cdd:COG4886 246 lgNLT-NLEELDLSNNQLTDLP--PLANLTNLKTLDLSNN 282
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
169-663 |
9.99e-13 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 72.57 E-value: 9.99e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 169 YFGNVCNQSFRVDG--------------AFEEIPNLKVLILSFNNLS-RVPPN---LPRSLTELYLSNTNIHSIGSRDFe 230
Cdd:PLN00113 60 WQGITCNNSSRVVSidlsgknisgkissAIFRLPYIQTINLSNNQLSgPIPDDiftTSSSLRYLNLSNNNFTGSIPRGS- 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 231 kLENLTVLDLSGNCprcFNAPFPcTPCAKDASIKIDD-----------HAFQKLSKLQYLNLSSTSL--QVIREIwfDNM 297
Cdd:PLN00113 139 -IPNLETLDLSNNM---LSGEIP-NDIGSFSSLKVLDlggnvlvgkipNSLTNLTSLEFLTLASNQLvgQIPREL--GQM 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 298 SSLKELHLEFNYLVHEIAsgNFLTKLPHLEILDLSYNYVKTQyalylnLSPNFSNLTSLRTLHLrgyvFQELRYEDFKP- 376
Cdd:PLN00113 212 KSLKWIYLGYNNLSGEIP--YEIGGLTSLNHLDLVYNNLTGP------IPSSLGNLKNLQYLFL----YQNKLSGPIPPs 279
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 377 LMKLSNLTTINLGVNFIK-QINFSVFQhLPNLNVIYLSENRIS----------PLVNDIRQSSANFSTVQSHVLKPRSAD 445
Cdd:PLN00113 280 IFSLQKLISLDLSDNSLSgEIPELVIQ-LQNLEILHLFSNNFTgkipvaltslPRLQVLQLWSNKFSGEIPKNLGKHNNL 358
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 446 NEFDPHSNfyHNTHPLMKQKCTRyGKAIDLSLNSIFFIGQ--KQFEAFPNISCLNLSSNGNAQALNgSEFSAVPHIKYLD 523
Cdd:PLN00113 359 TVLDLSTN--NLTGEIPEGLCSS-GNLFKLILFSNSLEGEipKSLGACRSLRRVRLQDNSFSGELP-SEFTKLPLVYFLD 434
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 524 LTHNKLDFDYDTALNELRELEVLDLSYNehyfRIAGVTHRLGFIKNLTKLDflnLSHNDIYTLTEYNLSSES-LTTLDFS 602
Cdd:PLN00113 435 ISNNNLQGRINSRKWDMPSLQMLSLARN----KFFGGLPDSFGSKRLENLD---LSRNQFSGAVPRKLGSLSeLMQLKLS 507
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1052247133 603 GNRLDVLWHAEdkrytyiFRNLNNLTWLDLSFNNLQ-QIPSkAFINLPRnLTHLFINDNKLS 663
Cdd:PLN00113 508 ENKLSGEIPDE-------LSSCKKLVSLDLSHNQLSgQIPA-SFSEMPV-LSQLDLSQNQLS 560
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
96-581 |
1.90e-10 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 65.25 E-value: 1.90e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 96 INKEGMNIT---DGAFFNLQNLTVLLLENNQLN-KIPSN---LPGSLRNLNLIQNNIISVTkhSTSGLKNLERLNLGWNC 168
Cdd:PLN00113 74 IDLSGKNISgkiSSAIFRLPYIQTINLSNNQLSgPIPDDiftTSSSLRYLNLSNNNFTGSI--PRGSIPNLETLDLSNNM 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 169 YFGNVCNQ--SF---------------RVDGAFEEIPNLKVLILSFNNLS-RVPPNLP--RSLTELYLSNTNIHSIGSRD 228
Cdd:PLN00113 152 LSGEIPNDigSFsslkvldlggnvlvgKIPNSLTNLTSLEFLTLASNQLVgQIPRELGqmKSLKWIYLGYNNLSGEIPYE 231
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 229 FEKLENLTVLDLSGNCprcFNAPFPCTpcakdasikiddhaFQKLSKLQYLNLSSTSL--QVIREIWfdNMSSLKELHLE 306
Cdd:PLN00113 232 IGGLTSLNHLDLVYNN---LTGPIPSS--------------LGNLKNLQYLFLYQNKLsgPIPPSIF--SLQKLISLDLS 292
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 307 FNYLVHEIASgnFLTKLPHLEILDLSYNYVKTQYALYLnlspnfSNLTSLRTLHLRGyvfQELRYEDFKPLMKLSNLTTI 386
Cdd:PLN00113 293 DNSLSGEIPE--LVIQLQNLEILHLFSNNFTGKIPVAL------TSLPRLQVLQLWS---NKFSGEIPKNLGKHNNLTVL 361
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 387 NLGVN---------------FIKQINFS--VFQHLP-------NLNVIYLSENRIS----------PLVNDIRQSSANFS 432
Cdd:PLN00113 362 DLSTNnltgeipeglcssgnLFKLILFSnsLEGEIPkslgacrSLRRVRLQDNSFSgelpseftklPLVYFLDISNNNLQ 441
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 433 -TVQSHVLKPRSADNEFDPHSNFYHNTHPLMKQKCTrygKAIDLSLNSIFFIGQKQFEAFPNISCLNLSSNgnaqALNG- 510
Cdd:PLN00113 442 gRINSRKWDMPSLQMLSLARNKFFGGLPDSFGSKRL---ENLDLSRNQFSGAVPRKLGSLSELMQLKLSEN----KLSGe 514
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1052247133 511 --SEFSAVPHIKYLDLTHNKLDFDYDTALNELRELEVLDLSYNEhyfrIAG-VTHRLGFIKNLTKldfLNLSHN 581
Cdd:PLN00113 515 ipDELSSCKKLVSLDLSHNQLSGQIPASFSEMPVLSQLDLSQNQ----LSGeIPKNLGNVESLVQ---VNISHN 581
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
298-755 |
3.69e-10 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 63.41 E-value: 3.69e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 298 SSLKELHLEFNYLVHEIASGNFLTKLPHLEILDLSYNYVKTQYALYLNLSPNFSNLTSLRTLHLRGYvfqelryedfKPL 377
Cdd:COG4886 40 LSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGN----------EEL 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 378 MKLSNLTTINLGVNFIKQINFSvFQHLPNLNVIYLSENRISPLVNDIRQssanfstvqshvlkprsadnefdphsnfyhn 457
Cdd:COG4886 110 SNLTNLESLDLSGNQLTDLPEE-LANLTNLKELDLSNNQLTDLPEPLGN------------------------------- 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 458 thplmkqkctrygkaidlslnsiffigqkqfeaFPNISCLNLSSNgNAQALnGSEFSAVPHIKYLDLTHNKLDfDYDTAL 537
Cdd:COG4886 158 ---------------------------------LTNLKSLDLSNN-QLTDL-PEELGNLTNLKELDLSNNQIT-DLPEPL 201
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 538 NELRELEVLDLSYNEhyfriagVTHRLGFIKNLTKLDFLNLSHNDIYTLTE-YNLSSesLTTLDFSGNRLDVLWHAEdkr 616
Cdd:COG4886 202 GNLTNLEELDLSGNQ-------LTDLPEPLANLTNLETLDLSNNQLTDLPElGNLTN--LEELDLSNNQLTDLPPLA--- 269
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 617 ytyifrNLNNLTWLDLSFN-----NLQQIPSKAFINLPRNLTHLFINDNKLSFFNWTLLETFSHLKLLDLSGNCLYFLTD 691
Cdd:COG4886 270 ------NLTNLKTLDLSNNqltdlKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALS 343
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1052247133 692 KLAKFAKSLKELILSRNHISHLPLGFLPEDSGLVHLDLSSNKLKTINRSTFPEKNTTLALLELH 755
Cdd:COG4886 344 LSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLTLAL 407
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
110-334 |
1.13e-09 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 62.41 E-value: 1.13e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 110 NLQ-NLTVLLLENNQLNKIPSNLPGSLRNLNLIQNNIISVTKHSTSGLKNLERLnlgwncyfgnvCNqsfRVDGAFEEIP 188
Cdd:PRK15370 217 NLQgNIKTLYANSNQLTSIPATLPDTIQEMELSINRITELPERLPSALQSLDLF-----------HN---KISCLPENLP 282
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 189 N-LKVLILSFNNLSRVPPNLPRSLTELYLSNTNIHSIGsrdfEKLE-NLTVLDLSGNCPRCFNAPFPctpcakdasikid 266
Cdd:PRK15370 283 EeLRYLSVYDNSIRTLPAHLPSGITHLNVQSNSLTALP----ETLPpGLKTLEAGENALTSLPASLP------------- 345
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1052247133 267 dhafqklSKLQYLNLSSTSLQVIREIWfdnMSSLKELHLEFNYLVheiasgNFLTKLP-HLEILDLSYN 334
Cdd:PRK15370 346 -------PELQVLDVSKNQITVLPETL---PPTITTLDVSRNALT------NLPENLPaALQIMQASRN 398
|
|
| TIR |
pfam01582 |
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular ... |
865-1009 |
4.50e-09 |
|
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular signalling domain found in MyD88, interleukin 1 receptor and the Toll receptor. It contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. TIR-like motifs are also found in plant proteins thought to be involved in resistance to disease. When activated, TIR domains recruit cytoplasmic adaptor proteins MyD88 and TOLLIP (Toll interacting protein). In turn, these associate with various kinases to set off signalling cascades.
Pssm-ID: 396246 [Multi-domain] Cd Length: 165 Bit Score: 56.60 E-value: 4.50e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 865 YDAYVSYDTKDasVTDWVINELRSHLEEsedKNVLLCLEERDWDPGLAIIDNLMQSINQSKKTIFVLTSKYARS-WS--- 940
Cdd:pfam01582 1 YDVFLSFRGSD--TREWFVSHLLKELKQ---KGIKLFIDDRDLEPGEAIAPELLSAIEKSRRSVVVLSPNYASSgWClde 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 941 FKTAFYLALQRlmdeNMDVI--------------------VFILLEPVLQHSQYLRLRQRICKSSILQWPDNPKAEGLFW 1000
Cdd:pfam01582 76 LVKILECALDL----GQKVIpifyevdpsdvrkqtgsfgkAFKKHKKVLTEEKVLKWRGALNEVANIWHSKSVSDESKFW 151
|
....*....
gi 1052247133 1001 QSLKNVVLT 1009
Cdd:pfam01582 152 KKIAYDISN 160
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
279-709 |
6.59e-09 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 59.18 E-value: 6.59e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 279 LNLSSTSLQVIREIWFDNMSSLKELHLEFNylvheiasgNFLTKLPHLEILDLSYNYVKtqyalylNLSPNFSNLTSLRT 358
Cdd:COG4886 77 LSLLLLSLLLLGLTDLGDLTNLTELDLSGN---------EELSNLTNLESLDLSGNQLT-------DLPEELANLTNLKE 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 359 LHLRGYVFQELRyedfKPLMKLSNLTTINLGVNFIKQINfSVFQHLPNLNVIYLSENRISPLvndirqssanfstvqshv 438
Cdd:COG4886 141 LDLSNNQLTDLP----EPLGNLTNLKSLDLSNNQLTDLP-EELGNLTNLKELDLSNNQITDL------------------ 197
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 439 lkprsadnefdphsnfyhnthplmkqkctrygkaidlslnsiffigQKQFEAFPNISCLNLSSNGNAQAlnGSEFSAVPH 518
Cdd:COG4886 198 ----------------------------------------------PEPLGNLTNLEELDLSGNQLTDL--PEPLANLTN 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 519 IKYLDLTHNKL-DFDYdtaLNELRELEVLDLSYNehyfRIAGvthrLGFIKNLTKLDFLNLSHNDIytlTEYNLSSESLT 597
Cdd:COG4886 230 LETLDLSNNQLtDLPE---LGNLTNLEELDLSNN----QLTD----LPPLANLTNLKTLDLSNNQL---TDLKLKELELL 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 598 TLDFSGNRLDVLWHAEDKRYTYIFRNLNNLTWLDLSFNNLQQIPSKAFINLPRNLTHLFINDNKLSFFNWTLLETFSHLK 677
Cdd:COG4886 296 LGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLL 375
|
410 420 430
....*....|....*....|....*....|..
gi 1052247133 678 LLDLSGNCLYFLTDKLAKFAKSLKELILSRNH 709
Cdd:COG4886 376 EATLLTLALLLLTLLLLLLTTTAGVLLLTLAL 407
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
37-418 |
1.23e-08 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 59.09 E-value: 1.23e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 37 NNRRLQEVPQTVSKDVTELDLSDNLIK-HITNE--SFQGLQALtkiNLNCNVMLppysknDHINKEGMNITDGAFFNL-- 111
Cdd:PLN00113 127 NNNFTGSIPRGSIPNLETLDLSNNMLSgEIPNDigSFSSLKVL---DLGGNVLV------GKIPNSLTNLTSLEFLTLas 197
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 112 --------------QNLTVLLLENNQLN-KIPSNLPG--SLRNLNLIQNNIISVTKHSTSGLKNLERLNLGWNCYFGNVC 174
Cdd:PLN00113 198 nqlvgqiprelgqmKSLKWIYLGYNNLSgEIPYEIGGltSLNHLDLVYNNLTGPIPSSLGNLKNLQYLFLYQNKLSGPIP 277
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 175 NQSFRV---------DGAFE-EIP-------NLKVLILSFNNLSRVPP----NLPRsLTELYLSNTNIHSIGSRDFEKLE 233
Cdd:PLN00113 278 PSIFSLqklisldlsDNSLSgEIPelviqlqNLEILHLFSNNFTGKIPvaltSLPR-LQVLQLWSNKFSGEIPKNLGKHN 356
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 234 NLTVLDLSGNcprCFNAPFPCTPCAKdasikiddhafqklSKLQYLNLSSTSLQVIREIWFDNMSSLKELHLEFNYLVHE 313
Cdd:PLN00113 357 NLTVLDLSTN---NLTGEIPEGLCSS--------------GNLFKLILFSNSLEGEIPKSLGACRSLRRVRLQDNSFSGE 419
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 314 IASGnfLTKLPHLEILDLSYNyvktqyALYLNLSPNFSNLTSLRTLHL-RGYVFQELryEDFKPLMKLSNLttiNLGVNF 392
Cdd:PLN00113 420 LPSE--FTKLPLVYFLDISNN------NLQGRINSRKWDMPSLQMLSLaRNKFFGGL--PDSFGSKRLENL---DLSRNQ 486
|
410 420
....*....|....*....|....*.
gi 1052247133 393 IKQINFSVFQHLPNLNVIYLSENRIS 418
Cdd:PLN00113 487 FSGAVPRKLGSLSELMQLKLSENKLS 512
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
36-353 |
1.25e-08 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 58.41 E-value: 1.25e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 36 CNNRRLQEVPQTVS--KDVTELDLSDNLIKHITnESFQGLQALTKINLNCNvmlppyskndhinkegmNITD--GAFFNL 111
Cdd:COG4886 143 LSNNQLTDLPEPLGnlTNLKSLDLSNNQLTDLP-EELGNLTNLKELDLSNN-----------------QITDlpEPLGNL 204
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 112 QNLTVLLLENNQLNKIPSNLPG--SLRNLNLIQNNIisvtkhstSGLKNLERLnlgwncyfgnvcnqsfrvdgafeeiPN 189
Cdd:COG4886 205 TNLEELDLSGNQLTDLPEPLANltNLETLDLSNNQL--------TDLPELGNL-------------------------TN 251
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 190 LKVLILSFNNLSRVPPNLP-RSLTELYLSNTNIHSIGSRDFEKLENLTVLDLSGNcpRCFNAPFPCTPCAKDASIKIDDH 268
Cdd:COG4886 252 LEELDLSNNQLTDLPPLANlTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLL--LLNLLELLILLLLLTTLLLLLLL 329
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 269 AFQKLSKLQYLNLSSTSLQVIREIWFDNMSSLKELHLEFNYLVHEIASGNFLTKLPHLEILDLSYNYVKTQYALYLNLSP 348
Cdd:COG4886 330 LKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLTLALLD 409
|
....*
gi 1052247133 349 NFSNL 353
Cdd:COG4886 410 AVNTE 414
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
524-759 |
1.33e-08 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 56.33 E-value: 1.33e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 524 LTH---NKLDFDYDTALNELRELEVLDLsYNEHYFRIAGvthrLGFIKNLTKLDflnLSHNDIYTLTeyNLSS-ESLTTL 599
Cdd:cd21340 4 ITHlylNDKNITKIDNLSLCKNLKVLYL-YDNKITKIEN----LEFLTNLTHLY---LQNNQIEKIE--NLENlVNLKKL 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 600 DFSGNRLDVLwhaedkrytyifRNLNNLTwldlsfnnlqqipskafinlprNLTHLFINDNKLSffnwtlletfshlkll 679
Cdd:cd21340 74 YLGGNRISVV------------EGLENLT----------------------NLEELHIENQRLP---------------- 103
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 680 dlSGNCLYFLTDKLAKFAKSLKELILSRNHISHL-PLGFLpedSGLVHLDLSSNKLKTINRSTFPEKN-TTLALLELHGN 757
Cdd:cd21340 104 --PGEKLTFDPRSLAALSNSLRVLNISGNNIDSLePLAPL---RNLEQLDASNNQISDLEELLDLLSSwPSLRELDLTGN 178
|
..
gi 1052247133 758 PF 759
Cdd:cd21340 179 PV 180
|
|
| TIR_2 |
pfam13676 |
TIR domain; This is a family of Toll-like receptors. |
868-979 |
1.61e-08 |
|
TIR domain; This is a family of Toll-like receptors.
Pssm-ID: 463954 [Multi-domain] Cd Length: 118 Bit Score: 53.86 E-value: 1.61e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 868 YVSYDTKDASVTDWVINELRSHleesedkNVLLCLEERDWDPGLAIIDNLMQSINQSKKTIFVLTSKYARSWSFKTAFYL 947
Cdd:pfam13676 2 FISYAGEDRAWAEWLADALEAA-------GYRVWLDRWDIRPGDDWVEEIEEAIENSDRVLVVLSPNYLESPWCRAEWEA 74
|
90 100 110
....*....|....*....|....*....|....*..
gi 1052247133 948 ALQRLMDENmdVIVFILLE-----PVLQHSQYLRLRQ 979
Cdd:pfam13676 75 ALADPEGRK--RLIPVRLEcdlelPGLAGLQYIDLRD 109
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
95-243 |
3.16e-08 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 55.18 E-value: 3.16e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 95 HINKEGMNITD-GAFFNLQNLTVLLLENNQLNKIPsNLpGSLRNL-NL-IQNNIISVTKHsTSGLKNLERLNLGWNC--- 168
Cdd:cd21340 6 HLYLNDKNITKiDNLSLCKNLKVLYLYDNKITKIE-NL-EFLTNLtHLyLQNNQIEKIEN-LENLVNLKKLYLGGNRisv 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 169 -------------YFGNVCNQS-----FRVDGAFEEIPNLKVLILSFNNLSRVPP--NLpRSLTELYLSNTNIHSIG--S 226
Cdd:cd21340 83 veglenltnleelHIENQRLPPgekltFDPRSLAALSNSLRVLNISGNNIDSLEPlaPL-RNLEQLDASNNQISDLEelL 161
|
170
....*....|....*..
gi 1052247133 227 RDFEKLENLTVLDLSGN 243
Cdd:cd21340 162 DLLSSWPSLRELDLTGN 178
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
174-334 |
4.22e-08 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 54.79 E-value: 4.22e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 174 CNQSFRVDGAFEEIPNLKVLILSFNNLSRVPpNLP--RSLTELYLSNTNIHSIgsRDFEKLENLTVLDLSGNCPRCF--- 248
Cdd:cd21340 10 NDKNITKIDNLSLCKNLKVLYLYDNKITKIE-NLEflTNLTHLYLQNNQIEKI--ENLENLVNLKKLYLGGNRISVVegl 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 249 --------------NAPfpctpcaKDASIKIDDHAFQKLSK-LQYLNLSSTSLQVIREIWfdNMSSLKELHLEFNYL--V 311
Cdd:cd21340 87 enltnleelhienqRLP-------PGEKLTFDPRSLAALSNsLRVLNISGNNIDSLEPLA--PLRNLEQLDASNNQIsdL 157
|
170 180
....*....|....*....|...
gi 1052247133 312 HEIAsgNFLTKLPHLEILDLSYN 334
Cdd:cd21340 158 EELL--DLLSSWPSLRELDLTGN 178
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
264-310 |
1.58e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 49.06 E-value: 1.58e-07
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 1052247133 264 KIDDHAFQKLSKLQYLNLSSTSLQVIREIWFDNMSSLKELHLEFNYL 310
Cdd:pfam13855 15 SLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
188-243 |
1.73e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 49.06 E-value: 1.73e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 188 PNLKVLILSFNNLSRVPP----NLPrSLTELYLSNTNIHSIGSRDFEKLENLTVLDLSGN 243
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDgafkGLS-NLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGN 59
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
573-734 |
4.36e-07 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 53.93 E-value: 4.36e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 573 LDFLNLSHNDIYTLTEYnLSSeSLTTLDFSGNRLDVLWHaedkrytyifrNL-NNLTWLDLSFNNLQQIPSkafiNLPRN 651
Cdd:PRK15370 243 IQEMELSINRITELPER-LPS-ALQSLDLFHNKISCLPE-----------NLpEELRYLSVYDNSIRTLPA----HLPSG 305
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 652 LTHLFINDNKLSFFNWTLLetfSHLKLLDLSGNCLYFLTDKLakfAKSLKELILSRNHISHLPLGFLPEdsgLVHLDLSS 731
Cdd:PRK15370 306 ITHLNVQSNSLTALPETLP---PGLKTLEAGENALTSLPASL---PPELQVLDVSKNQITVLPETLPPT---ITTLDVSR 376
|
...
gi 1052247133 732 NKL 734
Cdd:PRK15370 377 NAL 379
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
53-244 |
5.43e-07 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 52.74 E-value: 5.43e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 53 TELDLSDNlikHITNESFQGLQALTKInlncnvmlpPYSKNDHINKEGMNITDGAFF------NLQNLTVLLLENNQLNK 126
Cdd:cd00116 84 QELDLSDN---ALGPDGCGVLESLLRS---------SSLQELKLNNNGLGDRGLRLLakglkdLPPALEKLVLGRNRLEG 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 127 IPSN-----LP--GSLRNLNLIQNNI----ISVTKHSTSGLKNLERLNLgWNCYFGnvCNQSFRVDGAFEEIPNLKVLIL 195
Cdd:cd00116 152 ASCEalakaLRanRDLKELNLANNGIgdagIRALAEGLKANCNLEVLDL-NNNGLT--DEGASALAETLASLKSLEVLNL 228
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1052247133 196 SFNNLSRVP--------PNLPRSLTELYLSNTNIHSIGSRDF----EKLENLTVLDLSGNC 244
Cdd:cd00116 229 GDNNLTDAGaaalasalLSPNISLLTLSLSCNDITDDGAKDLaevlAEKESLLELDLRGNK 289
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
209-286 |
6.88e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 47.13 E-value: 6.88e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1052247133 209 RSLTELYLSNTNIHSIGSRDFEKLENLTVLDLSGNCPRCfnapfpctpcakdasikIDDHAFQKLSKLQYLNLSSTSL 286
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTT-----------------LSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
235-757 |
7.69e-07 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 53.31 E-value: 7.69e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 235 LTVLDLSGncprcfnapfpctpcaKDASIKIDDHAFQkLSKLQYLNLSSTSLQ-VIREIWFDNMSSLKELHLEFNYLVHE 313
Cdd:PLN00113 71 VVSIDLSG----------------KNISGKISSAIFR-LPYIQTINLSNNQLSgPIPDDIFTTSSSLRYLNLSNNNFTGS 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 314 IASGNfltkLPHLEILDLSYNYVKTQYAL---------YLNLSPNF---------SNLTSLRTLHLRGyvfQELRYEDFK 375
Cdd:PLN00113 134 IPRGS----IPNLETLDLSNNMLSGEIPNdigsfsslkVLDLGGNVlvgkipnslTNLTSLEFLTLAS---NQLVGQIPR 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 376 PLMKLSNLTTINLGVNFIK-QINFSVFQhLPNLNVIYLSENRispLVNDIRQSSANFSTVQSHVLKPRSADNEFdPHSNF 454
Cdd:PLN00113 207 ELGQMKSLKWIYLGYNNLSgEIPYEIGG-LTSLNHLDLVYNN---LTGPIPSSLGNLKNLQYLFLYQNKLSGPI-PPSIF 281
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 455 yhNTHPLMkqkctrygkAIDLSLNSIF-----FIGQKQfeafpNISCLNLSSNGNAQALNGSeFSAVPHIKYLDLTHNKL 529
Cdd:PLN00113 282 --SLQKLI---------SLDLSDNSLSgeipeLVIQLQ-----NLEILHLFSNNFTGKIPVA-LTSLPRLQVLQLWSNKF 344
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 530 DFDYDTALNELRELEVLDLSYNEHYFRIAGVTHRLGfikNLTKLDflnLSHNDIYTLTEYNLSS-ESLTTLDFSGNRLDV 608
Cdd:PLN00113 345 SGEIPKNLGKHNNLTVLDLSTNNLTGEIPEGLCSSG---NLFKLI---LFSNSLEGEIPKSLGAcRSLRRVRLQDNSFSG 418
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 609 LWHAEdkrytyiFRNLNNLTWLDLSFNNLQ--------QIPSKAFINLPRNlthlfindnklSFFNwTLLETF--SHLKL 678
Cdd:PLN00113 419 ELPSE-------FTKLPLVYFLDISNNNLQgrinsrkwDMPSLQMLSLARN-----------KFFG-GLPDSFgsKRLEN 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 679 LDLSGNCLY-FLTDKLAKFAKsLKELILSRNHIShlplGFLPED----SGLVHLDLSSNKLKTINRSTFPEKnTTLALLE 753
Cdd:PLN00113 480 LDLSRNQFSgAVPRKLGSLSE-LMQLKLSENKLS----GEIPDElsscKKLVSLDLSHNQLSGQIPASFSEM-PVLSQLD 553
|
....
gi 1052247133 754 LHGN 757
Cdd:PLN00113 554 LSQN 557
|
|
| PCC |
TIGR00864 |
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) ... |
728-810 |
1.32e-06 |
|
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) Polycystin is a huge protein of 4303aas. Its repeated leucine-rich (LRR) segment is found in many proteins. It contains 16 polycystic kidney disease (PKD) domains, one LDL-receptor class A domain, one C-type lectin family domain, and 16-18 putative TMSs in positions between residues 2200 and 4100. Polycystin-L has been shown to be a cation (Na+, K+ and Ca2+) channel that is activated by Ca2+. Two members of the PCC family (polycystin 1 and 2) are mutated in autosomal dominant polycystic kidney disease, and polycystin-L is deleted in mice with renal and retinal defects. Note: this model is restricted to the amino half.
Pssm-ID: 188093 [Multi-domain] Cd Length: 2740 Bit Score: 52.78 E-value: 1.32e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 728 DLSSNKLKTINRSTFpEKNTTLALLELHGNPFDCTCDMGDFRSWMdKHQNVTIPRLTDVLCASPGDQIGKSIMSLELTTC 807
Cdd:TIGR00864 1 DISNNKISTIEEGIC-ANLCNLSEIDLSGNPFECDCGLARLPRWA-EEKGVKVRQPEAALCAGPGALAGQPLLGIPLLDS 78
|
...
gi 1052247133 808 VSD 810
Cdd:TIGR00864 79 GCD 81
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
37-221 |
1.82e-06 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 52.01 E-value: 1.82e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 37 NNRRLQEVPQTVSKDVTELDLSDNLIKHITNESFQGLQALtkiNLNCNVM--LPPyskndhinkegmNITDGaffnLQNL 114
Cdd:PRK15370 228 NSNQLTSIPATLPDTIQEMELSINRITELPERLPSALQSL---DLFHNKIscLPE------------NLPEE----LRYL 288
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 115 TVLlleNNQLNKIPSNLPGSLRNLNLIQNNIISVTKHSTSGLKNLERLNLGWNCY-------FGNVCNQSFRVDGAFEEI 187
Cdd:PRK15370 289 SVY---DNSIRTLPAHLPSGITHLNVQSNSLTALPETLPPGLKTLEAGENALTSLpaslppeLQVLDVSKNQITVLPETL 365
|
170 180 190
....*....|....*....|....*....|....*
gi 1052247133 188 P-NLKVLILSFNNLSRVPPNLPRSLTELYLSNTNI 221
Cdd:PRK15370 366 PpTITTLDVSRNALTNLPENLPAALQIMQASRNNL 400
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
274-334 |
2.35e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 45.59 E-value: 2.35e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1052247133 274 SKLQYLNLSSTSLQVIREIWFDNMSSLKELHLEFNYLVHeiASGNFLTKLPHLEILDLSYN 334
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTT--LSPGAFSGLPSLRYLDLSGN 59
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
594-758 |
3.57e-06 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 50.05 E-value: 3.57e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 594 ESLTTLDFSGN---RLDVLWHAEDKrytyIFRNLNNLTWLDLSFNNLQQIPSKAFINLPRN--LTHLFINDNKLS----- 663
Cdd:cd00116 51 PSLKELCLSLNetgRIPRGLQSLLQ----GLTKGCGLQELDLSDNALGPDGCGVLESLLRSssLQELKLNNNGLGdrglr 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 664 FFNWTLLETFSHLKLLDLSGNCLY----FLTDKLAKFAKSLKELILSRNHIS-----HLPLGfLPEDSGLVHLDLSSNKL 734
Cdd:cd00116 127 LLAKGLKDLPPALEKLVLGRNRLEgascEALAKALRANRDLKELNLANNGIGdagirALAEG-LKANCNLEVLDLNNNGL 205
|
170 180
....*....|....*....|....*..
gi 1052247133 735 KTINRSTF---PEKNTTLALLELHGNP 758
Cdd:cd00116 206 TDEGASALaetLASLKSLEVLNLGDNN 232
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
595-662 |
3.79e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 45.21 E-value: 3.79e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1052247133 595 SLTTLDFSGNRLDVLwhaEDKrytyIFRNLNNLTWLDLSFNNLQQIPSKAFINLPrNLTHLFINDNKL 662
Cdd:pfam13855 2 NLRSLDLSNNRLTSL---DDG----AFKGLSNLKVLDLSNNLLTTLSPGAFSGLP-SLRYLDLSGNRL 61
|
|
| PRK15387 |
PRK15387 |
type III secretion system effector E3 ubiquitin transferase SspH2; |
586-759 |
7.78e-06 |
|
type III secretion system effector E3 ubiquitin transferase SspH2;
Pssm-ID: 185285 [Multi-domain] Cd Length: 788 Bit Score: 50.16 E-value: 7.78e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 586 LTEYNLSSESLTTLDFSGNRLDVLWhAEDKRYTYIFRNLNNLTWLDLSFNNLQQIPSkafinLPRNLTHLFINDNKLSff 665
Cdd:PRK15387 304 LQELSVSDNQLASLPALPSELCKLW-AYNNQLTSLPTLPSGLQELSVSDNQLASLPT-----LPSELYKLWAYNNRLT-- 375
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 666 nwTLLETFSHLKLLDLSGNCLyfltDKLAKFAKSLKELILSRNHISHLPLgfLPedSGLVHLDLSSNKLKTINRSTFPEK 745
Cdd:PRK15387 376 --SLPALPSGLKELIVSGNRL----TSLPVLPSELKELMVSGNRLTSLPM--LP--SGLLSLSVYRNQLTRLPESLIHLS 445
|
170
....*....|....
gi 1052247133 746 NTTLALLElhGNPF 759
Cdd:PRK15387 446 SETTVNLE--GNPL 457
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
52-124 |
1.27e-05 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 43.67 E-value: 1.27e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1052247133 52 VTELDLSDNLIKHITNESFQGLQALTKINLNCNVMlppysknDHINkegmnitDGAFFNLQNLTVLLLENNQL 124
Cdd:pfam13855 3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLL-------TTLS-------PGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
298-363 |
7.00e-05 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 41.36 E-value: 7.00e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1052247133 298 SSLKELHLEFNYLVHeIASGNFlTKLPHLEILDLSYNYVKTqyalylnLSPN-FSNLTSLRTLHLRG 363
Cdd:pfam13855 1 PNLRSLDLSNNRLTS-LDDGAF-KGLSNLKVLDLSNNLLTT-------LSPGaFSGLPSLRYLDLSG 58
|
|
| LRRCT |
smart00082 |
Leucine rich repeat C-terminal domain; |
757-797 |
1.02e-04 |
|
Leucine rich repeat C-terminal domain;
Pssm-ID: 214507 [Multi-domain] Cd Length: 51 Bit Score: 40.88 E-value: 1.02e-04
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 1052247133 757 NPFDCTCDMGDFRSWmdKHQNVTIPRLTDVLCASPGDQIGK 797
Cdd:smart00082 1 NPFICDCELRWLLRW--LQANEHLQDPVDLRCASPSSLRGP 39
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
650-710 |
1.17e-04 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 40.97 E-value: 1.17e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1052247133 650 RNLTHLFINDNKLSFFNWTLLETFSHLKLLDLSGNCLYFLTDKLAKFAKSLKELILSRNHI 710
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
488-703 |
1.84e-04 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 44.01 E-value: 1.84e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 488 FEAFPNISCLNLSSNgNAQALNGSEFSavPHIKYLDLTHN---KLDFdydtaLNELRELEVLDLSYNehyfRIAgvthRL 564
Cdd:cd21340 20 LSLCKNLKVLYLYDN-KITKIENLEFL--TNLTHLYLQNNqieKIEN-----LENLVNLKKLYLGGN----RIS----VV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 565 GFIKNLTKLDFLNLSHN----------DIYTLTeynLSSESLTTLDFSGNRLDVLwhaEDkrytyiFRNLNNLTWLDLSF 634
Cdd:cd21340 84 EGLENLTNLEELHIENQrlppgekltfDPRSLA---ALSNSLRVLNISGNNIDSL---EP------LAPLRNLEQLDASN 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1052247133 635 NNLQqipskafinlprNLTHLFindnklsffnwTLLETFSHLKLLDLSGNCL-----YFltDKLAKFAKSLKEL 703
Cdd:cd21340 152 NQIS------------DLEELL-----------DLLSSWPSLRELDLTGNPVckkpkYR--DKIILASKSLEVL 200
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
699-759 |
1.99e-04 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 40.20 E-value: 1.99e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1052247133 699 SLKELILSRNHISHLPLGFLPEDSGLVHLDLSSNKLKTINRSTFpEKNTTLALLELHGNPF 759
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAF-SGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
492-551 |
4.19e-04 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 39.43 E-value: 4.19e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 492 PNISCLNLSSNgNAQALNGSEFSAVPHIKYLDLTHNKLDFDYDTALNELRELEVLDLSYN 551
Cdd:pfam13855 1 PNLRSLDLSNN-RLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGN 59
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
112-167 |
5.63e-04 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 39.04 E-value: 5.63e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 1052247133 112 QNLTVLLLENNQLNKIPSNLPGSLRNL---NLIQNNIISVTKHSTSGLKNLERLNLGWN 167
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLkvlDLSNNLLTTLSPGAFSGLPSLRYLDLSGN 59
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
674-734 |
8.59e-04 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 38.66 E-value: 8.59e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1052247133 674 SHLKLLDLSGNCLYFLTDKLAKFAKSLKELILSRNHISHLPLGFLPEDSGLVHLDLSSNKL 734
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
517-583 |
1.11e-03 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 38.27 E-value: 1.11e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1052247133 517 PHIKYLDLTHNKLDFDYDTALNELRELEVLDLSYN--EHYFRIAgvthrlgfIKNLTKLDFLNLSHNDI 583
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNllTTLSPGA--------FSGLPSLRYLDLSGNRL 61
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
108-222 |
1.24e-03 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 42.91 E-value: 1.24e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 108 FFNLQNLTVLLLENNQLNK-IPSNLPG--SLRNLNLIQNNIISVTKHSTSGLKNLERLNLGWNcyfgnvcNQSFRVDGAF 184
Cdd:PLN00113 471 SFGSKRLENLDLSRNQFSGaVPRKLGSlsELMQLKLSENKLSGEIPDELSSCKKLVSLDLSHN-------QLSGQIPASF 543
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 1052247133 185 EEIPNLKVLILSFNNLS-RVPPNLPR--SLTELYLSNTNIH 222
Cdd:PLN00113 544 SEMPVLSQLDLSQNQLSgEIPKNLGNveSLVQVNISHNHLH 584
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
268-418 |
1.38e-03 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 41.96 E-value: 1.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 268 HAFQKLSKLQYLNLSSTSLQvireiwFDNM---------SSLKELHLEFNYLvhEIASGNFLTK-----LPHLEILDLSY 333
Cdd:cd00116 75 QGLTKGCGLQELDLSDNALG------PDGCgvlesllrsSSLQELKLNNNGL--GDRGLRLLAKglkdlPPALEKLVLGR 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 334 NYVKTQYAlyLNLSPNFSNLTSLRTLHLRGYVFQELRYEDFKPLMK-LSNLTTINLGVNFIKQINFS----VFQHLPNLN 408
Cdd:cd00116 147 NRLEGASC--EALAKALRANRDLKELNLANNGIGDAGIRALAEGLKaNCNLEVLDLNNNGLTDEGASalaeTLASLKSLE 224
|
170
....*....|
gi 1052247133 409 VIYLSENRIS 418
Cdd:cd00116 225 VLNLGDNNLT 234
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
473-529 |
1.54e-03 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 37.89 E-value: 1.54e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 1052247133 473 IDLSLNSIFFIGQKQFEAFPNISCLNLSSNgNAQALNGSEFSAVPHIKYLDLTHNKL 529
Cdd:pfam13855 6 LDLSNNRLTSLDDGAFKGLSNLKVLDLSNN-LLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
354-417 |
2.13e-03 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 37.50 E-value: 2.13e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1052247133 354 TSLRTLHLRGYVFQELRYEDFKplmKLSNLTTINLGVNFIKQINFSVFQHLPNLNVIYLSENRI 417
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFK---GLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
541-735 |
2.74e-03 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 41.19 E-value: 2.74e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 541 RELEVLDLSYNEHYFRIAGVTHRLGFIKNLTKLDFLNLSHN----DIYTLTEYNLSSESLTTLDFSGNRLDVLwhAEDKR 616
Cdd:cd00116 51 PSLKELCLSLNETGRIPRGLQSLLQGLTKGCGLQELDLSDNalgpDGCGVLESLLRSSSLQELKLNNNGLGDR--GLRLL 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 617 YTYIFRNLNNLTWLDLSFNNLQQIP----SKAFINLPRnLTHLFINDNKLSFFNWTLL----ETFSHLKLLDLSGNCLyf 688
Cdd:cd00116 129 AKGLKDLPPALEKLVLGRNRLEGAScealAKALRANRD-LKELNLANNGIGDAGIRALaeglKANCNLEVLDLNNNGL-- 205
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1052247133 689 lTDKLAKF-------AKSLKELILSRNHI-----SHLPLGFLPEDSGLVHLDLSSNKLK 735
Cdd:cd00116 206 -TDEGASAlaetlasLKSLEVLNLGDNNLtdagaAALASALLSPNISLLTLSLSCNDIT 263
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
134-200 |
5.21e-03 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 36.35 E-value: 5.21e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1052247133 134 SLRNLNLIQNNIISVTKHSTSGLKNLERLNLGWNCYfgnvcnqSFRVDGAFEEIPNLKVLILSFNNL 200
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLL-------TTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
381-418 |
5.80e-03 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 35.96 E-value: 5.80e-03
10 20 30
....*....|....*....|....*....|....*...
gi 1052247133 381 SNLTTINLGVNFIKQINFSVFQHLPNLNVIYLSENRIS 418
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLT 38
|
|
| LRR_4 |
pfam12799 |
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ... |
210-243 |
6.32e-03 |
|
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.
Pssm-ID: 463713 [Multi-domain] Cd Length: 44 Bit Score: 35.68 E-value: 6.32e-03
10 20 30
....*....|....*....|....*....|....
gi 1052247133 210 SLTELYLSNTNIHSIGSrdFEKLENLTVLDLSGN 243
Cdd:pfam12799 2 NLEVLDLSNNQITDIPP--LAKLPNLETLDLSGN 33
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
301-606 |
7.89e-03 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 39.65 E-value: 7.89e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 301 KELHLEFNYLVHEIASgNFLTKLPHLEILDLSYNYVKTQYALYLnlspnFSNLT---SLRTLHLRGYVFQELRYEDFKPL 377
Cdd:cd00116 1 LQLSLKGELLKTERAT-ELLPKLLCLQVLRLEGNTLGEEAAKAL-----ASALRpqpSLKELCLSLNETGRIPRGLQSLL 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 378 M---KLSNLTTINLGVNFIKQIN---FSVFQHLPNLNVIYLSENRISPLVNDIRQSSanfstvqshvLKPRSadnefdph 451
Cdd:cd00116 75 QgltKGCGLQELDLSDNALGPDGcgvLESLLRSSSLQELKLNNNGLGDRGLRLLAKG----------LKDLP-------- 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 452 snfyhntHPLMKQKCTR----YGKAIDLSlnsiffigqKQFEAFPNISCLNLSSNG----NAQALnGSEFSAVPHIKYLD 523
Cdd:cd00116 137 -------PALEKLVLGRnrleGASCEALA---------KALRANRDLKELNLANNGigdaGIRAL-AEGLKANCNLEVLD 199
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247133 524 LTHNKLDFDYDTALNE----LRELEVLDLSYNEhyFRIAGVTHRL-GFIKNLTKLDFLNLSHNDIY-----TLTEYNLSS 593
Cdd:cd00116 200 LNNNGLTDEGASALAEtlasLKSLEVLNLGDNN--LTDAGAAALAsALLSPNISLLTLSLSCNDITddgakDLAEVLAEK 277
|
330
....*....|...
gi 1052247133 594 ESLTTLDFSGNRL 606
Cdd:cd00116 278 ESLLELDLRGNKF 290
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
158-221 |
8.87e-03 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 35.58 E-value: 8.87e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1052247133 158 NLERLNLgWNCYFGNVCnqsfrvDGAFEEIPNLKVLILSFNNLSRVPPNL---PRSLTELYLSNTNI 221
Cdd:pfam13855 2 NLRSLDL-SNNRLTSLD------DGAFKGLSNLKVLDLSNNLLTTLSPGAfsgLPSLRYLDLSGNRL 61
|
|
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