|
Name |
Accession |
Description |
Interval |
E-value |
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
452-762 |
6.65e-20 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 93.46 E-value: 6.65e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 452 LSNFYHSTNPLIKPQCTTYGKALDLSLNNIFFIGQKQFEAFQNEIACLNLSSNDNAQALNGTEFSAVSNVKYLDLSHNKL 531
Cdd:COG4886 2 LLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 532 DFDSDLA---FSELTKLEVLDLSYNAHyfqiagvthrlgfIKNLTKLNILNLSYNSIYTLTEYNLSSVSLQELVFSGNCL 608
Cdd:COG4886 82 LSLLLLGltdLGDLTNLTELDLSGNEE-------------LSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQL 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 609 DQLwhaeddryNAIFKGLRNLTRLDLSYNKLQRIPDEaFVNLPqNLTELYINNNYLQFFNWSlLQQFVHLNLLDLSRNHL 688
Cdd:COG4886 149 TDL--------PEPLGNLTNLKSLDLSNNQLTDLPEE-LGNLT-NLKELDLSNNQITDLPEP-LGNLTNLEELDLSGNQL 217
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1052247137 689 YFLTYSLSKFTpSLQTLLLSHNRIFHLPSgfLSEARNLVHLDLSYNKLQTINRSTlqtqNTTKLAVLQLHKNPF 762
Cdd:COG4886 218 TDLPEPLANLT-NLETLDLSNNQLTDLPE--LGNLTNLEELDLSNNQLTDLPPLA----NLTNLKTLDLSNNQL 284
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
95-511 |
4.15e-16 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 81.90 E-value: 4.15e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 95 YTNKNGLTITDGAFFDLQNLTELLLEDNQLNKIPANLPRSLKTLSLIQNNIVFITENNTSGLGNLETLYLGWNCYFGNAC 174
Cdd:COG4886 19 ELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNL 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 175 NQTFCLSNRTFKETTNLKVLSLSFNNLSQVPHNLPR--SLTNLYLSNTNIHVIHRgDFKKLENLRVLDLSGNcpkcfnap 252
Cdd:COG4886 99 TELDLSGNEELSNLTNLESLDLSGNQLTDLPEELANltNLKELDLSNNQLTDLPE-PLGNLTNLKSLDLSNN-------- 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 253 fpctpcpggaSIVIDNLAFHDLSNLQILNLSSTSLRKIPATwFDKMHHLKELYLQFNNLAQEimsGDFLAKLPVLEILDL 332
Cdd:COG4886 170 ----------QLTDLPEELGNLTNLKELDLSNNQITDLPEP-LGNLTNLEELDLSGNQLTDL---PEPLANLTNLETLDL 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 333 SFNYIKgdypaniNISSkFINLKSLRELHLEGyvfqeLRQKDLEPLANLSNLTTINLGVNFIKQIDFTFFRNHRNLKVVY 412
Cdd:COG4886 236 SNNQLT-------DLPE-LGNLTNLEELDLSN-----NQLTDLPPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLL 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 413 LSLNRISPLVNGIRQYDANDSTGQSHIRKPRSANNKFDPLSNfyhstNPLIKPQCTTYGKALDLSLNNIFFIGQKQFEAF 492
Cdd:COG4886 303 LLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSL-----SLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEA 377
|
410
....*....|....*....
gi 1052247137 493 QNEIACLNLSSNDNAQALN 511
Cdd:COG4886 378 TLLTLALLLLTLLLLLLTT 396
|
|
| TIR |
smart00255 |
Toll - interleukin 1 - resistance; |
868-1004 |
3.61e-15 |
|
Toll - interleukin 1 - resistance;
Pssm-ID: 214587 [Multi-domain] Cd Length: 140 Bit Score: 73.51 E-value: 3.61e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 868 YDAYVSYdtkdaSVTDWVINELRFHLEESEEKNVLlCLEERDWDPGLAVIDNLMQSINQSKKTIFVLTKKYARSWSFKTA 947
Cdd:smart00255 2 YDVFISY-----SGKEDVRNEFLSHLLEKLRGYGL-CVFIDDFEPGGGDLEEIDEAIEKSRIAIVVLSPNYAESEWCLDE 75
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1052247137 948 FYLALQRLMDENMDVIVFILLEP----VLQHSQYLRLRQRIcksSILQWPDNPKaeDLFWQ 1004
Cdd:smart00255 76 LVAALENALEEGGLRVIPIFYEVipsdVRKQPGKFRKVFKK---NYLKWPEDEK--EQFWK 131
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
49-606 |
7.96e-15 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 79.51 E-value: 7.96e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 49 SKYVTELDLSSNFITLITNESFRGLGNLTKINLNHNVVLPPYIENHYTNKNGL------------TITDGAFFDLQNLTe 116
Cdd:PLN00113 68 SSRVVSIDLSGKNISGKISSAIFRLPYIQTINLSNNQLSGPIPDDIFTTSSSLrylnlsnnnftgSIPRGSIPNLETLD- 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 117 llLEDNQLN-KIPANLP--RSLKTLSLIQNNIVFITENNTSGLGNLETLYLgwncyfgnACNQTFCLSNRTFKETTNLKV 193
Cdd:PLN00113 147 --LSNNMLSgEIPNDIGsfSSLKVLDLGGNVLVGKIPNSLTNLTSLEFLTL--------ASNQLVGQIPRELGQMKSLKW 216
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 194 LSLSFNNLS-QVPHNLPR--SLTNLYLSNTNIHVIHRGDFKKLENLRVLDLSGNcpkCFNAPFPctpcpggASIVidnla 270
Cdd:PLN00113 217 IYLGYNNLSgEIPYEIGGltSLNHLDLVYNNLTGPIPSSLGNLKNLQYLFLYQN---KLSGPIP-------PSIF----- 281
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 271 fhDLSNLQILNLSSTSLR-KIPATwFDKMHHLKELYLQFNNLAQEIMSGdfLAKLPVLEILDLSFNYIKGDYPANINISS 349
Cdd:PLN00113 282 --SLQKLISLDLSDNSLSgEIPEL-VIQLQNLEILHLFSNNFTGKIPVA--LTSLPRLQVLQLWSNKFSGEIPKNLGKHN 356
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 350 KFINLkSLRELHLEGyvfqelrqKDLEPLANLSNLTTINLGVNFIKQIDFTFFRNHRNLKVVYLSLNRIS---------- 419
Cdd:PLN00113 357 NLTVL-DLSTNNLTG--------EIPEGLCSSGNLFKLILFSNSLEGEIPKSLGACRSLRRVRLQDNSFSgelpseftkl 427
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 420 PLVNGIrQYDANDSTGQSHIRK---PR------SANNKFDPLSNFYHSTNPlikpqcttygKALDLSLNNIFFIGQKQFE 490
Cdd:PLN00113 428 PLVYFL-DISNNNLQGRINSRKwdmPSlqmlslARNKFFGGLPDSFGSKRL----------ENLDLSRNQFSGAVPRKLG 496
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 491 AFqNEIACLNLSSNDnaqaLNG---TEFSAVSNVKYLDLSHNKLDFDSDLAFSELTKLEVLDLSYNahyfQIAG-VTHRL 566
Cdd:PLN00113 497 SL-SELMQLKLSENK----LSGeipDELSSCKKLVSLDLSHNQLSGQIPASFSEMPVLSQLDLSQN----QLSGeIPKNL 567
|
570 580 590 600
....*....|....*....|....*....|....*....|....
gi 1052247137 567 GFIKNLTKLNI----LNLSYNSIYTLTEYNLSSVSLQELVFSGN 606
Cdd:PLN00113 568 GNVESLVQVNIshnhLHGSLPSTGAFLAINASAVAGNIDLCGGD 611
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
269-736 |
2.46e-13 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 74.50 E-value: 2.46e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 269 LAFHDLSNLQILNLSSTSLR-KIPATWFDKMHHLKELYLQFNNLAQEIMSGdflaKLPVLEILDLSFNYIKGDYPANINI 347
Cdd:PLN00113 87 SAIFRLPYIQTINLSNNQLSgPIPDDIFTTSSSLRYLNLSNNNFTGSIPRG----SIPNLETLDLSNNMLSGEIPNDIGS 162
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 348 SSkfinlkSLRELHLEGYVfqeLRQKDLEPLANLSNLTTINLGVN-FIKQIDFTFFRnHRNLKVVYLSLNRISplvnGIR 426
Cdd:PLN00113 163 FS------SLKVLDLGGNV---LVGKIPNSLTNLTSLEFLTLASNqLVGQIPRELGQ-MKSLKWIYLGYNNLS----GEI 228
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 427 QYDANDSTGQSHirkprsannkfdpLSNFYhstNPLIKPQCTTYGkalDLSLNNIFFIGQKQFE--------AFQNEIAc 498
Cdd:PLN00113 229 PYEIGGLTSLNH-------------LDLVY---NNLTGPIPSSLG---NLKNLQYLFLYQNKLSgpippsifSLQKLIS- 288
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 499 LNLSSNdnaqALNGTEFSAVSNVKYLDLSH---NKLDFDSDLAFSELTKLEVLDLSYNAHYfqiAGVTHRLGFIKNLTkl 575
Cdd:PLN00113 289 LDLSDN----SLSGEIPELVIQLQNLEILHlfsNNFTGKIPVALTSLPRLQVLQLWSNKFS---GEIPKNLGKHNNLT-- 359
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 576 nILNLSYNSIY-TLTEYNLSSVSLQELVFSGNCLDqlwhaeddryNAIFKGL---RNLTRLDLSYNKLQRIPDEAFVNLP 651
Cdd:PLN00113 360 -VLDLSTNNLTgEIPEGLCSSGNLFKLILFSNSLE----------GEIPKSLgacRSLRRVRLQDNSFSGELPSEFTKLP 428
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 652 QnLTELYINNNYLQFFNWSLLQQFVHLNLLDLSRNHlYFLTYSLSKFTPSLQTLLLSHNRIFH-LPSGF----------- 719
Cdd:PLN00113 429 L-VYFLDISNNNLQGRINSRKWDMPSLQMLSLARNK-FFGGLPDSFGSKRLENLDLSRNQFSGaVPRKLgslselmqlkl 506
|
490 500
....*....|....*....|....*....
gi 1052247137 720 ------------LSEARNLVHLDLSYNKL 736
Cdd:PLN00113 507 senklsgeipdeLSSCKKLVSLDLSHNQL 535
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
627-688 |
1.45e-10 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 57.53 E-value: 1.45e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1052247137 627 RNLTRLDLSYNKLQRIPDEAFVNLPqNLTELYINNNYLQFFNWSLLQQFVHLNLLDLSRNHL 688
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLS-NLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| TIR |
pfam01582 |
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular ... |
868-986 |
7.86e-09 |
|
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular signalling domain found in MyD88, interleukin 1 receptor and the Toll receptor. It contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. TIR-like motifs are also found in plant proteins thought to be involved in resistance to disease. When activated, TIR domains recruit cytoplasmic adaptor proteins MyD88 and TOLLIP (Toll interacting protein). In turn, these associate with various kinases to set off signalling cascades.
Pssm-ID: 396246 [Multi-domain] Cd Length: 165 Bit Score: 55.83 E-value: 7.86e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 868 YDAYVSYDTKDasVTDWVINELRFHLEEseeKNVLLCLEERDWDPGLAVIDNLMQSINQSKKTIFVLTKKYARS-WS--- 943
Cdd:pfam01582 1 YDVFLSFRGSD--TREWFVSHLLKELKQ---KGIKLFIDDRDLEPGEAIAPELLSAIEKSRRSVVVLSPNYASSgWClde 75
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 1052247137 944 FKTAFYLALQRlmdeNMDVIvFILLEPVLQHSQ-----YLRLRQRICK 986
Cdd:pfam01582 76 LVKILECALDL----GQKVI-PIFYEVDPSDVRkqtgsFGKAFKKHKK 118
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
112-244 |
3.14e-08 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 55.18 E-value: 3.14e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 112 QNLTELLLEDNQLNKIPaNLP--RSLKTLSLIQNNIVFIteNNTSGLGNLETLYLGWNC----------------YFGN- 172
Cdd:cd21340 24 KNLKVLYLYDNKITKIE-NLEflTNLTHLYLQNNQIEKI--ENLENLVNLKKLYLGGNRisvveglenltnleelHIENq 100
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1052247137 173 --ACNQTFCLSNRTFKETTN-LKVLSLSFNNLSQVP--HNLpRSLTNLYLSNTNIHVIHR--GDFKKLENLRVLDLSGN 244
Cdd:cd21340 101 rlPPGEKLTFDPRSLAALSNsLRVLNISGNNIDSLEplAPL-RNLEQLDASNNQISDLEEllDLLSSWPSLRELDLTGN 178
|
|
| PCC |
TIGR00864 |
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) ... |
730-813 |
3.53e-08 |
|
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) Polycystin is a huge protein of 4303aas. Its repeated leucine-rich (LRR) segment is found in many proteins. It contains 16 polycystic kidney disease (PKD) domains, one LDL-receptor class A domain, one C-type lectin family domain, and 16-18 putative TMSs in positions between residues 2200 and 4100. Polycystin-L has been shown to be a cation (Na+, K+ and Ca2+) channel that is activated by Ca2+. Two members of the PCC family (polycystin 1 and 2) are mutated in autosomal dominant polycystic kidney disease, and polycystin-L is deleted in mice with renal and retinal defects. Note: this model is restricted to the amino half.
Pssm-ID: 188093 [Multi-domain] Cd Length: 2740 Bit Score: 58.17 E-value: 3.53e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 730 DLSYNKLQTINRSTLQTQntTKLAVLQLHKNPFDCTCDLGDFRRWMDENlHVRIPRLAAITCDSPGNQRGKSIIKLELTT 809
Cdd:TIGR00864 1 DISNNKISTIEEGICANL--CNLSEIDLSGNPFECDCGLARLPRWAEEK-GVKVRQPEAALCAGPGALAGQPLLGIPLLD 77
|
....
gi 1052247137 810 CVSD 813
Cdd:TIGR00864 78 SGCD 81
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
623-762 |
1.05e-07 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 53.64 E-value: 1.05e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 623 FKGLRNLTRLDLSYNKLQRIpdEAFVNLPqNLTELYINNNYLQffnwsllqqfvhlnlldlSRNHLYFLTYSLSKFTPSL 702
Cdd:cd21340 64 LENLVNLKKLYLGGNRISVV--EGLENLT-NLEELHIENQRLP------------------PGEKLTFDPRSLAALSNSL 122
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 703 QTLLLSHNRIFHLpsGFLSEARNLVHLDLSYNKLQTINRSTLQTQNTTKLAVLQLHKNPF 762
Cdd:cd21340 123 RVLNISGNNIDSL--EPLAPLRNLEQLDASNNQISDLEELLDLLSSWPSLRELDLTGNPV 180
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
275-337 |
2.11e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 48.67 E-value: 2.11e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1052247137 275 SNLQILNLSSTSLRKIPATWFDKMHHLKELYLQFNNLaqEIMSGDFLAKLPVLEILDLSFNYI 337
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLL--TTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
52-124 |
2.92e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 45.59 E-value: 2.92e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1052247137 52 VTELDLSSNFITLITNESFRGLGNLTKINLNHNvvlppyienhytnkNGLTITDGAFFDLQNLTELLLEDNQL 124
Cdd:pfam13855 3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNN--------------LLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRRCT |
smart00082 |
Leucine rich repeat C-terminal domain; |
760-800 |
3.75e-06 |
|
Leucine rich repeat C-terminal domain;
Pssm-ID: 214507 [Multi-domain] Cd Length: 51 Bit Score: 44.73 E-value: 3.75e-06
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 1052247137 760 NPFDCTCDLGDFRRWMDENlhVRIPRLAAITCDSPGNQRGK 800
Cdd:smart00082 1 NPFICDCELRWLLRWLQAN--EHLQDPVDLRCASPSSLRGP 39
|
|
| LRR |
smart00370 |
Leucine-rich repeats, outliers; |
626-647 |
8.27e-03 |
|
Leucine-rich repeats, outliers;
Pssm-ID: 197688 [Multi-domain] Cd Length: 24 Bit Score: 34.63 E-value: 8.27e-03
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
452-762 |
6.65e-20 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 93.46 E-value: 6.65e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 452 LSNFYHSTNPLIKPQCTTYGKALDLSLNNIFFIGQKQFEAFQNEIACLNLSSNDNAQALNGTEFSAVSNVKYLDLSHNKL 531
Cdd:COG4886 2 LLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 532 DFDSDLA---FSELTKLEVLDLSYNAHyfqiagvthrlgfIKNLTKLNILNLSYNSIYTLTEYNLSSVSLQELVFSGNCL 608
Cdd:COG4886 82 LSLLLLGltdLGDLTNLTELDLSGNEE-------------LSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQL 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 609 DQLwhaeddryNAIFKGLRNLTRLDLSYNKLQRIPDEaFVNLPqNLTELYINNNYLQFFNWSlLQQFVHLNLLDLSRNHL 688
Cdd:COG4886 149 TDL--------PEPLGNLTNLKSLDLSNNQLTDLPEE-LGNLT-NLKELDLSNNQITDLPEP-LGNLTNLEELDLSGNQL 217
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1052247137 689 YFLTYSLSKFTpSLQTLLLSHNRIFHLPSgfLSEARNLVHLDLSYNKLQTINRSTlqtqNTTKLAVLQLHKNPF 762
Cdd:COG4886 218 TDLPEPLANLT-NLETLDLSNNQLTDLPE--LGNLTNLEELDLSNNQLTDLPPLA----NLTNLKTLDLSNNQL 284
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
511-760 |
3.39e-17 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 85.37 E-value: 3.39e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 511 NGTEFSAVSNVKYLDLSHNKLDfDSDLAFSELTKLEVLDLSYNahyfqiaGVTHRLGFIKNLTKLNILNLSYNSIYTLTE 590
Cdd:COG4886 105 GNEELSNLTNLESLDLSGNQLT-DLPEELANLTNLKELDLSNN-------QLTDLPEPLGNLTNLKSLDLSNNQLTDLPE 176
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 591 YNLSSVSLQELVFSGNCLDQLwhaeddryNAIFKGLRNLTRLDLSYNKLQRIPDEaFVNLPqNLTELYINNNYLQffNWS 670
Cdd:COG4886 177 ELGNLTNLKELDLSNNQITDL--------PEPLGNLTNLEELDLSGNQLTDLPEP-LANLT-NLETLDLSNNQLT--DLP 244
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 671 LLQQFVHLNLLDLSRNHLYFLtySLSKFTPSLQTLLLSHNRIFHLPSGFLSEARNLVHLDLSYNKLQTINRSTLQTQNTT 750
Cdd:COG4886 245 ELGNLTNLEELDLSNNQLTDL--PPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTT 322
|
250
....*....|
gi 1052247137 751 KLAVLQLHKN 760
Cdd:COG4886 323 LLLLLLLLKG 332
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
95-511 |
4.15e-16 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 81.90 E-value: 4.15e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 95 YTNKNGLTITDGAFFDLQNLTELLLEDNQLNKIPANLPRSLKTLSLIQNNIVFITENNTSGLGNLETLYLGWNCYFGNAC 174
Cdd:COG4886 19 ELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNL 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 175 NQTFCLSNRTFKETTNLKVLSLSFNNLSQVPHNLPR--SLTNLYLSNTNIHVIHRgDFKKLENLRVLDLSGNcpkcfnap 252
Cdd:COG4886 99 TELDLSGNEELSNLTNLESLDLSGNQLTDLPEELANltNLKELDLSNNQLTDLPE-PLGNLTNLKSLDLSNN-------- 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 253 fpctpcpggaSIVIDNLAFHDLSNLQILNLSSTSLRKIPATwFDKMHHLKELYLQFNNLAQEimsGDFLAKLPVLEILDL 332
Cdd:COG4886 170 ----------QLTDLPEELGNLTNLKELDLSNNQITDLPEP-LGNLTNLEELDLSGNQLTDL---PEPLANLTNLETLDL 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 333 SFNYIKgdypaniNISSkFINLKSLRELHLEGyvfqeLRQKDLEPLANLSNLTTINLGVNFIKQIDFTFFRNHRNLKVVY 412
Cdd:COG4886 236 SNNQLT-------DLPE-LGNLTNLEELDLSN-----NQLTDLPPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLL 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 413 LSLNRISPLVNGIRQYDANDSTGQSHIRKPRSANNKFDPLSNfyhstNPLIKPQCTTYGKALDLSLNNIFFIGQKQFEAF 492
Cdd:COG4886 303 LLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSL-----SLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEA 377
|
410
....*....|....*....
gi 1052247137 493 QNEIACLNLSSNDNAQALN 511
Cdd:COG4886 378 TLLTLALLLLTLLLLLLTT 396
|
|
| TIR |
smart00255 |
Toll - interleukin 1 - resistance; |
868-1004 |
3.61e-15 |
|
Toll - interleukin 1 - resistance;
Pssm-ID: 214587 [Multi-domain] Cd Length: 140 Bit Score: 73.51 E-value: 3.61e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 868 YDAYVSYdtkdaSVTDWVINELRFHLEESEEKNVLlCLEERDWDPGLAVIDNLMQSINQSKKTIFVLTKKYARSWSFKTA 947
Cdd:smart00255 2 YDVFISY-----SGKEDVRNEFLSHLLEKLRGYGL-CVFIDDFEPGGGDLEEIDEAIEKSRIAIVVLSPNYAESEWCLDE 75
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1052247137 948 FYLALQRLMDENMDVIVFILLEP----VLQHSQYLRLRQRIcksSILQWPDNPKaeDLFWQ 1004
Cdd:smart00255 76 LVAALENALEEGGLRVIPIFYEVipsdVRKQPGKFRKVFKK---NYLKWPEDEK--EQFWK 131
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
49-606 |
7.96e-15 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 79.51 E-value: 7.96e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 49 SKYVTELDLSSNFITLITNESFRGLGNLTKINLNHNVVLPPYIENHYTNKNGL------------TITDGAFFDLQNLTe 116
Cdd:PLN00113 68 SSRVVSIDLSGKNISGKISSAIFRLPYIQTINLSNNQLSGPIPDDIFTTSSSLrylnlsnnnftgSIPRGSIPNLETLD- 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 117 llLEDNQLN-KIPANLP--RSLKTLSLIQNNIVFITENNTSGLGNLETLYLgwncyfgnACNQTFCLSNRTFKETTNLKV 193
Cdd:PLN00113 147 --LSNNMLSgEIPNDIGsfSSLKVLDLGGNVLVGKIPNSLTNLTSLEFLTL--------ASNQLVGQIPRELGQMKSLKW 216
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 194 LSLSFNNLS-QVPHNLPR--SLTNLYLSNTNIHVIHRGDFKKLENLRVLDLSGNcpkCFNAPFPctpcpggASIVidnla 270
Cdd:PLN00113 217 IYLGYNNLSgEIPYEIGGltSLNHLDLVYNNLTGPIPSSLGNLKNLQYLFLYQN---KLSGPIP-------PSIF----- 281
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 271 fhDLSNLQILNLSSTSLR-KIPATwFDKMHHLKELYLQFNNLAQEIMSGdfLAKLPVLEILDLSFNYIKGDYPANINISS 349
Cdd:PLN00113 282 --SLQKLISLDLSDNSLSgEIPEL-VIQLQNLEILHLFSNNFTGKIPVA--LTSLPRLQVLQLWSNKFSGEIPKNLGKHN 356
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 350 KFINLkSLRELHLEGyvfqelrqKDLEPLANLSNLTTINLGVNFIKQIDFTFFRNHRNLKVVYLSLNRIS---------- 419
Cdd:PLN00113 357 NLTVL-DLSTNNLTG--------EIPEGLCSSGNLFKLILFSNSLEGEIPKSLGACRSLRRVRLQDNSFSgelpseftkl 427
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 420 PLVNGIrQYDANDSTGQSHIRK---PR------SANNKFDPLSNFYHSTNPlikpqcttygKALDLSLNNIFFIGQKQFE 490
Cdd:PLN00113 428 PLVYFL-DISNNNLQGRINSRKwdmPSlqmlslARNKFFGGLPDSFGSKRL----------ENLDLSRNQFSGAVPRKLG 496
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 491 AFqNEIACLNLSSNDnaqaLNG---TEFSAVSNVKYLDLSHNKLDFDSDLAFSELTKLEVLDLSYNahyfQIAG-VTHRL 566
Cdd:PLN00113 497 SL-SELMQLKLSENK----LSGeipDELSSCKKLVSLDLSHNQLSGQIPASFSEMPVLSQLDLSQN----QLSGeIPKNL 567
|
570 580 590 600
....*....|....*....|....*....|....*....|....
gi 1052247137 567 GFIKNLTKLNI----LNLSYNSIYTLTEYNLSSVSLQELVFSGN 606
Cdd:PLN00113 568 GNVESLVQVNIshnhLHGSLPSTGAFLAINASAVAGNIDLCGGD 611
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
375-758 |
1.19e-14 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 77.28 E-value: 1.19e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 375 LEPLANLSNLTTINLGVNFIKQIDFTFFRNHRNLKVVYLSLNRISPLVNGIRQYDANDSTGQSHIRKPRSANNKFDPLSN 454
Cdd:COG4886 2 LLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 455 FYHSTNPLIKPQCTTYGKALDLSLNNIFFIGQKqfeafqneIACLNLSSNdNAQALnGTEFSAVSNVKYLDLSHNKLDfD 534
Cdd:COG4886 82 LSLLLLGLTDLGDLTNLTELDLSGNEELSNLTN--------LESLDLSGN-QLTDL-PEELANLTNLKELDLSNNQLT-D 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 535 SDLAFSELTKLEVLDLSYNahyfQIAGVTHrlgFIKNLTKLNILNLSYNSIYTLTE--YNLSSvsLQELVFSGNCLDQLw 612
Cdd:COG4886 151 LPEPLGNLTNLKSLDLSNN----QLTDLPE---ELGNLTNLKELDLSNNQITDLPEplGNLTN--LEELDLSGNQLTDL- 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 613 haeddryNAIFKGLRNLTRLDLSYNKLQRIPDeaFVNLPqNLTELYINNNYLQFFnwSLLQQFVHLNLLDLSRNHLYFLT 692
Cdd:COG4886 221 -------PEPLANLTNLETLDLSNNQLTDLPE--LGNLT-NLEELDLSNNQLTDL--PPLANLTNLKTLDLSNNQLTDLK 288
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1052247137 693 YSLSKFTPSLQTLLLSHNRIFHLPSGFLSEARNLVHLDLSYNKLQTINRSTLQTQNTTKLAVLQLH 758
Cdd:COG4886 289 LKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLL 354
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
269-736 |
2.46e-13 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 74.50 E-value: 2.46e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 269 LAFHDLSNLQILNLSSTSLR-KIPATWFDKMHHLKELYLQFNNLAQEIMSGdflaKLPVLEILDLSFNYIKGDYPANINI 347
Cdd:PLN00113 87 SAIFRLPYIQTINLSNNQLSgPIPDDIFTTSSSLRYLNLSNNNFTGSIPRG----SIPNLETLDLSNNMLSGEIPNDIGS 162
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 348 SSkfinlkSLRELHLEGYVfqeLRQKDLEPLANLSNLTTINLGVN-FIKQIDFTFFRnHRNLKVVYLSLNRISplvnGIR 426
Cdd:PLN00113 163 FS------SLKVLDLGGNV---LVGKIPNSLTNLTSLEFLTLASNqLVGQIPRELGQ-MKSLKWIYLGYNNLS----GEI 228
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 427 QYDANDSTGQSHirkprsannkfdpLSNFYhstNPLIKPQCTTYGkalDLSLNNIFFIGQKQFE--------AFQNEIAc 498
Cdd:PLN00113 229 PYEIGGLTSLNH-------------LDLVY---NNLTGPIPSSLG---NLKNLQYLFLYQNKLSgpippsifSLQKLIS- 288
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 499 LNLSSNdnaqALNGTEFSAVSNVKYLDLSH---NKLDFDSDLAFSELTKLEVLDLSYNAHYfqiAGVTHRLGFIKNLTkl 575
Cdd:PLN00113 289 LDLSDN----SLSGEIPELVIQLQNLEILHlfsNNFTGKIPVALTSLPRLQVLQLWSNKFS---GEIPKNLGKHNNLT-- 359
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 576 nILNLSYNSIY-TLTEYNLSSVSLQELVFSGNCLDqlwhaeddryNAIFKGL---RNLTRLDLSYNKLQRIPDEAFVNLP 651
Cdd:PLN00113 360 -VLDLSTNNLTgEIPEGLCSSGNLFKLILFSNSLE----------GEIPKSLgacRSLRRVRLQDNSFSGELPSEFTKLP 428
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 652 QnLTELYINNNYLQFFNWSLLQQFVHLNLLDLSRNHlYFLTYSLSKFTPSLQTLLLSHNRIFH-LPSGF----------- 719
Cdd:PLN00113 429 L-VYFLDISNNNLQGRINSRKWDMPSLQMLSLARNK-FFGGLPDSFGSKRLENLDLSRNQFSGaVPRKLgslselmqlkl 506
|
490 500
....*....|....*....|....*....
gi 1052247137 720 ------------LSEARNLVHLDLSYNKL 736
Cdd:PLN00113 507 senklsgeipdeLSSCKKLVSLDLSHNQL 535
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
140-421 |
1.44e-12 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 70.73 E-value: 1.44e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 140 LIQNNIVFITENNTSGLGNLETLYLGWNCYFGNACNQTFCLSNRTFKETTNLKVLSLSFNNLSQVPHNLPRSLTNLYLSN 219
Cdd:COG4886 2 LLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 220 TNIHVIHRGDFKKLENLRVLDLSGNCPkcfnapfpctpcpggasividnlaFHDLSNLQILNLSSTSLRKIPAtWFDKMH 299
Cdd:COG4886 82 LSLLLLGLTDLGDLTNLTELDLSGNEE------------------------LSNLTNLESLDLSGNQLTDLPE-ELANLT 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 300 HLKELYLQFNNLAQEimsGDFLAKLPVLEILDLSFNYIKgdypaniNISSKFINLKSLRELHLEGYVFQELRqkdlEPLA 379
Cdd:COG4886 137 NLKELDLSNNQLTDL---PEPLGNLTNLKSLDLSNNQLT-------DLPEELGNLTNLKELDLSNNQITDLP----EPLG 202
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 1052247137 380 NLSNLTTINLGVNFIKQIDFTfFRNHRNLKVVYLSLNRISPL 421
Cdd:COG4886 203 NLTNLEELDLSGNQLTDLPEP-LANLTNLETLDLSNNQLTDL 243
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
122-419 |
5.68e-12 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 68.81 E-value: 5.68e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 122 NQLNKIPANLPRSLKTLSLIQNNIVFITENNTSGLGNLETLYLGWNCYFGNACNQTFCLSNRTFKETTNLKVLSLSFNNL 201
Cdd:COG4886 1 LLLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 202 SQVPHNLPRSLTNLYLSNTNIHVIHRGDFKKLENLRVLDLSGNcpkcfnapfpctpcpggaSIVIDNLAFHDLSNLQILN 281
Cdd:COG4886 81 LLSLLLLGLTDLGDLTNLTELDLSGNEELSNLTNLESLDLSGN------------------QLTDLPEELANLTNLKELD 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 282 LSSTSLRKIPAtWFDKMHHLKELYLQFNNLAQEimsGDFLAKLPVLEILDLSFNYIKgdypaniNISSKFINLKSLRELH 361
Cdd:COG4886 143 LSNNQLTDLPE-PLGNLTNLKSLDLSNNQLTDL---PEELGNLTNLKELDLSNNQIT-------DLPEPLGNLTNLEELD 211
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 1052247137 362 LEGYVFQELRqkdlEPLANLSNLTTINLGVNFIKQIDftFFRNHRNLKVVYLSLNRIS 419
Cdd:COG4886 212 LSGNQLTDLP----EPLANLTNLETLDLSNNQLTDLP--ELGNLTNLEELDLSNNQLT 263
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
185-689 |
2.59e-11 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 67.95 E-value: 2.59e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 185 FKETTNLKVLSLSFNNLS-QVPHNLPRSLTNLYLSNTNIHVIHRGDFKKLENLRVLDLSGNCpkcfnapfpctpCPGGAS 263
Cdd:PLN00113 114 FTTSSSLRYLNLSNNNFTgSIPRGSIPNLETLDLSNNMLSGEIPNDIGSFSSLKVLDLGGNV------------LVGKIP 181
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 264 IVIDNLafhdlSNLQILNLSSTSLR-KIPATwFDKMHHLKELYLQFNNLAQEIMSGdfLAKLPVLEILDLSFNYIKGDYP 342
Cdd:PLN00113 182 NSLTNL-----TSLEFLTLASNQLVgQIPRE-LGQMKSLKWIYLGYNNLSGEIPYE--IGGLTSLNHLDLVYNNLTGPIP 253
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 343 aninisSKFINLKSLRELHLegyvFQELRQKDLEP-LANLSNLTTINLGVNFIKQIDFTFFRNHRNLKVVYLSLNRISPL 421
Cdd:PLN00113 254 ------SSLGNLKNLQYLFL----YQNKLSGPIPPsIFSLQKLISLDLSDNSLSGEIPELVIQLQNLEILHLFSNNFTGK 323
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 422 VNG---------IRQYDANDSTGQshIRKPRSANNKFDPLSnfyHSTNPL---IKPQCTTYGKALDLslnnIFFIGQKQF 489
Cdd:PLN00113 324 IPValtslprlqVLQLWSNKFSGE--IPKNLGKHNNLTVLD---LSTNNLtgeIPEGLCSSGNLFKL----ILFSNSLEG 394
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 490 EAFQNEIAC-----LNLSSNDNAQALNgTEFSAVSNVKYLDLSHNKLDFDSDLAFSELTKLEVLDLSYNAHYfqiAGVTH 564
Cdd:PLN00113 395 EIPKSLGACrslrrVRLQDNSFSGELP-SEFTKLPLVYFLDISNNNLQGRINSRKWDMPSLQMLSLARNKFF---GGLPD 470
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 565 RLGfIKNLTKlniLNLSYNSIYTLTEYNLSSVS-LQELVFSGNCLDQLWHAEddrynaiFKGLRNLTRLDLSYNKLQ-RI 642
Cdd:PLN00113 471 SFG-SKRLEN---LDLSRNQFSGAVPRKLGSLSeLMQLKLSENKLSGEIPDE-------LSSCKKLVSLDLSHNQLSgQI 539
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|
gi 1052247137 643 PDeAFVNLPQnLTELYINNNYLQF---FNWSLLQQFVHLNlldLSRNHLY 689
Cdd:PLN00113 540 PA-SFSEMPV-LSQLDLSQNQLSGeipKNLGNVESLVQVN---ISHNHLH 584
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
62-416 |
2.68e-11 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 66.88 E-value: 2.68e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 62 ITLITNESFRGLGNLTKINLNHNVV--LPPYIENhytnkngltitdgaffdLQNLTELLLEDNQLNKIPANLPR--SLKT 137
Cdd:COG4886 101 LDLSGNEELSNLTNLESLDLSGNQLtdLPEELAN-----------------LTNLKELDLSNNQLTDLPEPLGNltNLKS 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 138 LSLIQNNIVFITENntsgLGNLetlylgwncyfgnacnqtfclsnrtfketTNLKVLSLSFNNLSQVPHNL--PRSLTNL 215
Cdd:COG4886 164 LDLSNNQLTDLPEE----LGNL-----------------------------TNLKELDLSNNQITDLPEPLgnLTNLEEL 210
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 216 YLSNTNIHVIHRgDFKKLENLRVLDLSGNCpkcfnapfpctpcpggasivIDNL-AFHDLSNLQILNLSSTSLRKIPATw 294
Cdd:COG4886 211 DLSGNQLTDLPE-PLANLTNLETLDLSNNQ--------------------LTDLpELGNLTNLEELDLSNNQLTDLPPL- 268
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 295 fDKMHHLKELYLQFNNLAQ-EIMSGDFLAKLPVLEILDLSFNYIKGDYPANINISSKFINLKSLRELHLEGYVFQELRQK 373
Cdd:COG4886 269 -ANLTNLKTLDLSNNQLTDlKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLL 347
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 1052247137 374 DLEPLANLSNLTTINLGVNFIKQIDFTFFRNHRNLKVVYLSLN 416
Cdd:COG4886 348 ALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLL 390
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
627-688 |
1.45e-10 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 57.53 E-value: 1.45e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1052247137 627 RNLTRLDLSYNKLQRIPDEAFVNLPqNLTELYINNNYLQFFNWSLLQQFVHLNLLDLSRNHL 688
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLS-NLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
113-365 |
5.00e-10 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 63.56 E-value: 5.00e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 113 NLTELLLEDNQLNKIPANLPRSLKTLSLIQNNIVFITENNTSGLGNLETlylgwncyfgnACNQTFCLSNRTFKEttnLK 192
Cdd:PRK15370 221 NIKTLYANSNQLTSIPATLPDTIQEMELSINRITELPERLPSALQSLDL-----------FHNKISCLPENLPEE---LR 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 193 VLSLSFNNLSQVPHNLPRSLTNLYLSNTNIHVIHRgdfKKLENLRVLDLSGNCPKCFNAPFPctpcPGgasivIDNLafh 272
Cdd:PRK15370 287 YLSVYDNSIRTLPAHLPSGITHLNVQSNSLTALPE---TLPPGLKTLEAGENALTSLPASLP----PE-----LQVL--- 351
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 273 DLSNLQILNLSSTslrkIPATwfdkmhhLKELYLQFNNLAqeimsgDFLAKLP-VLEILDLSFNYI------------KG 339
Cdd:PRK15370 352 DVSKNQITVLPET----LPPT-------ITTLDVSRNALT------NLPENLPaALQIMQASRNNLvrlpeslphfrgEG 414
|
250 260 270
....*....|....*....|....*....|
gi 1052247137 340 DYPANINISSKFINLKSLRELHL----EGY 365
Cdd:PRK15370 415 PQPTRIIVEYNPFSERTIQNMQRlmssVGY 444
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
258-753 |
9.73e-10 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 61.87 E-value: 9.73e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 258 CPGGASIVIDNLAFHDLSNLQILNLSSTSLRKIPATWFDKMHHLKELYLQFNNLAQEIMSGDFLAKLPVLEILDLSFNyi 337
Cdd:COG4886 2 LLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSL-- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 338 kGDYPANINISSKFINLKSLRELHLEGyvfqelrqkdLEPLANLSNLTTINLGVNFIKQIDFtFFRNHRNLKVVYLSLNR 417
Cdd:COG4886 80 -LLLSLLLLGLTDLGDLTNLTELDLSG----------NEELSNLTNLESLDLSGNQLTDLPE-ELANLTNLKELDLSNNQ 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 418 ISPLVNGIRQydandstgqshirkprsannkfdpLSNFyhstnplikpqcttygKALDLSLNNIFFIGqkqfeafqneia 497
Cdd:COG4886 148 LTDLPEPLGN------------------------LTNL----------------KSLDLSNNQLTDLP------------ 175
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 498 clnlssndnaqalngTEFSAVSNVKYLDLSHNKLDfDSDLAFSELTKLEVLDLSYNAhyfqiagVTHRLGFIKNLTKLNI 577
Cdd:COG4886 176 ---------------EELGNLTNLKELDLSNNQIT-DLPEPLGNLTNLEELDLSGNQ-------LTDLPEPLANLTNLET 232
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 578 LNLSYNSIYTLTE-YNLSSvsLQELVFSGNCLDQLwhaeddrynAIFKGLRNLTRLDLSYNKLQRIPDEAFVNLPQNLTE 656
Cdd:COG4886 233 LDLSNNQLTDLPElGNLTN--LEELDLSNNQLTDL---------PPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSL 301
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 657 LYINNNYLQFFNWSLLQQFVHLNLLDLSRNHLYFLTYSLSKFTPSLQTLLLSHNRIFHLPSGFLSEARNLVHLDLSYNKL 736
Cdd:COG4886 302 LLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLT 381
|
490
....*....|....*..
gi 1052247137 737 QTINRSTLQTQNTTKLA 753
Cdd:COG4886 382 LALLLLTLLLLLLTTTA 398
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
262-711 |
4.31e-09 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 59.95 E-value: 4.31e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 262 ASIVIDNLAFHDLSNLQILNLSSTSLRKIPATWFDKMHHLKELYLQFNNlaqeimsgdFLAKLPVLEILDLSFNYIKgDY 341
Cdd:COG4886 59 DLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNE---------ELSNLTNLESLDLSGNQLT-DL 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 342 PANINisskfiNLKSLRELHLEGYVFQELRqkdlEPLANLSNLTTINLGVNFIKQIDfTFFRNHRNLKVVYLSLNRISPL 421
Cdd:COG4886 129 PEELA------NLTNLKELDLSNNQLTDLP----EPLGNLTNLKSLDLSNNQLTDLP-EELGNLTNLKELDLSNNQITDL 197
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 422 VNGIRQydandstgqshirkprsannkfdpLSNFyhstnplikpqcttygKALDLSLNNIFFIGQkqfeafqneiaclnl 501
Cdd:COG4886 198 PEPLGN------------------------LTNL----------------EELDLSGNQLTDLPE--------------- 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 502 ssndnaqalngtEFSAVSNVKYLDLSHNKLdfdSDL-AFSELTKLEVLDLSYNahyfQIAGvthrLGFIKNLTKLNILNL 580
Cdd:COG4886 223 ------------PLANLTNLETLDLSNNQL---TDLpELGNLTNLEELDLSNN----QLTD----LPPLANLTNLKTLDL 279
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 581 SYNSIYTLTEYNLSSVSLQELVFSGNCLDQLWHAEDDRYNAIFKGLRNLTRLDLSYNKLQRIPDEAFVNLPQNLTELYIN 660
Cdd:COG4886 280 SNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLL 359
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|.
gi 1052247137 661 NNYLQFFNWSLLQQFVHLNLLDLSRNHLYFLTYSLSKFTPSLQTLLLSHNR 711
Cdd:COG4886 360 SLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLTLALLDA 410
|
|
| TIR |
pfam01582 |
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular ... |
868-986 |
7.86e-09 |
|
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular signalling domain found in MyD88, interleukin 1 receptor and the Toll receptor. It contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. TIR-like motifs are also found in plant proteins thought to be involved in resistance to disease. When activated, TIR domains recruit cytoplasmic adaptor proteins MyD88 and TOLLIP (Toll interacting protein). In turn, these associate with various kinases to set off signalling cascades.
Pssm-ID: 396246 [Multi-domain] Cd Length: 165 Bit Score: 55.83 E-value: 7.86e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 868 YDAYVSYDTKDasVTDWVINELRFHLEEseeKNVLLCLEERDWDPGLAVIDNLMQSINQSKKTIFVLTKKYARS-WS--- 943
Cdd:pfam01582 1 YDVFLSFRGSD--TREWFVSHLLKELKQ---KGIKLFIDDRDLEPGEAIAPELLSAIEKSRRSVVVLSPNYASSgWClde 75
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 1052247137 944 FKTAFYLALQRlmdeNMDVIvFILLEPVLQHSQ-----YLRLRQRICK 986
Cdd:pfam01582 76 LVKILECALDL----GQKVI-PIFYEVDPSDVRkqtgsFGKAFKKHKK 118
|
|
| TIR_2 |
pfam13676 |
TIR domain; This is a family of Toll-like receptors. |
871-982 |
1.60e-08 |
|
TIR domain; This is a family of Toll-like receptors.
Pssm-ID: 463954 [Multi-domain] Cd Length: 118 Bit Score: 53.86 E-value: 1.60e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 871 YVSYDTKDASVTDWVINELrfhleesEEKNVLLCLEERDWDPGLAVIDNLMQSINQSKKTIFVLTKKYARSWSFKTAFYL 950
Cdd:pfam13676 2 FISYAGEDRAWAEWLADAL-------EAAGYRVWLDRWDIRPGDDWVEEIEEAIENSDRVLVVLSPNYLESPWCRAEWEA 74
|
90 100 110
....*....|....*....|....*....|....*..
gi 1052247137 951 ALQRLMDENmdVIVFILLE-----PVLQHSQYLRLRQ 982
Cdd:pfam13676 75 ALADPEGRK--RLIPVRLEcdlelPGLAGLQYIDLRD 109
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
112-244 |
3.14e-08 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 55.18 E-value: 3.14e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 112 QNLTELLLEDNQLNKIPaNLP--RSLKTLSLIQNNIVFIteNNTSGLGNLETLYLGWNC----------------YFGN- 172
Cdd:cd21340 24 KNLKVLYLYDNKITKIE-NLEflTNLTHLYLQNNQIEKI--ENLENLVNLKKLYLGGNRisvveglenltnleelHIENq 100
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1052247137 173 --ACNQTFCLSNRTFKETTN-LKVLSLSFNNLSQVP--HNLpRSLTNLYLSNTNIHVIHR--GDFKKLENLRVLDLSGN 244
Cdd:cd21340 101 rlPPGEKLTFDPRSLAALSNsLRVLNISGNNIDSLEplAPL-RNLEQLDASNNQISDLEEllDLLSSWPSLRELDLTGN 178
|
|
| PCC |
TIGR00864 |
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) ... |
730-813 |
3.53e-08 |
|
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) Polycystin is a huge protein of 4303aas. Its repeated leucine-rich (LRR) segment is found in many proteins. It contains 16 polycystic kidney disease (PKD) domains, one LDL-receptor class A domain, one C-type lectin family domain, and 16-18 putative TMSs in positions between residues 2200 and 4100. Polycystin-L has been shown to be a cation (Na+, K+ and Ca2+) channel that is activated by Ca2+. Two members of the PCC family (polycystin 1 and 2) are mutated in autosomal dominant polycystic kidney disease, and polycystin-L is deleted in mice with renal and retinal defects. Note: this model is restricted to the amino half.
Pssm-ID: 188093 [Multi-domain] Cd Length: 2740 Bit Score: 58.17 E-value: 3.53e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 730 DLSYNKLQTINRSTLQTQntTKLAVLQLHKNPFDCTCDLGDFRRWMDENlHVRIPRLAAITCDSPGNQRGKSIIKLELTT 809
Cdd:TIGR00864 1 DISNNKISTIEEGICANL--CNLSEIDLSGNPFECDCGLARLPRWAEEK-GVKVRQPEAALCAGPGALAGQPLLGIPLLD 77
|
....
gi 1052247137 810 CVSD 813
Cdd:TIGR00864 78 SGCD 81
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
623-762 |
1.05e-07 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 53.64 E-value: 1.05e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 623 FKGLRNLTRLDLSYNKLQRIpdEAFVNLPqNLTELYINNNYLQffnwsllqqfvhlnlldlSRNHLYFLTYSLSKFTPSL 702
Cdd:cd21340 64 LENLVNLKKLYLGGNRISVV--EGLENLT-NLEELHIENQRLP------------------PGEKLTFDPRSLAALSNSL 122
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 703 QTLLLSHNRIFHLpsGFLSEARNLVHLDLSYNKLQTINRSTLQTQNTTKLAVLQLHKNPF 762
Cdd:cd21340 123 RVLNISGNNIDSL--EPLAPLRNLEQLDASNNQISDLEELLDLLSSWPSLRELDLTGNPV 180
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
25-209 |
2.06e-07 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 55.09 E-value: 2.06e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 25 ETRQNSSVIAECSGLDLREVPKGVSKYVTELDLSSNFITLITNESFRGLGNLTKINLNHNVV---LPPYIENHYTNKNGL 101
Cdd:PRK15370 237 ATLPDTIQEMELSINRITELPERLPSALQSLDLFHNKISCLPENLPEELRYLSVYDNSIRTLpahLPSGITHLNVQSNSL 316
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 102 TITDGAFfdLQNLTELLLEDNQLNKIPANLPRSLKTLSLIQNNIVFITENNTSglgNLETLYLGWNCyfgnacnqtfcLS 181
Cdd:PRK15370 317 TALPETL--PPGLKTLEAGENALTSLPASLPPELQVLDVSKNQITVLPETLPP---TITTLDVSRNA-----------LT 380
|
170 180
....*....|....*....|....*...
gi 1052247137 182 NRTFKETTNLKVLSLSFNNLSQVPHNLP 209
Cdd:PRK15370 381 NLPENLPAALQIMQASRNNLVRLPESLP 408
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
275-337 |
2.11e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 48.67 E-value: 2.11e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1052247137 275 SNLQILNLSSTSLRKIPATWFDKMHHLKELYLQFNNLaqEIMSGDFLAKLPVLEILDLSFNYI 337
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLL--TTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
210-287 |
3.25e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 48.29 E-value: 3.25e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1052247137 210 RSLTNLYLSNTNIHVIHRGDFKKLENLRVLDLSGNCPKcfnapfpctpcpggasiVIDNLAFHDLSNLQILNLSSTSL 287
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLT-----------------TLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
444-736 |
7.65e-07 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 53.31 E-value: 7.65e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 444 SANNKFDPLSNfYHSTNPLIKPQ---CTTYG--KALDLSLNNIffIGQKQFEAFQ-NEIACLNLSSNDNAQALNGTEFSA 517
Cdd:PLN00113 40 SINDPLKYLSN-WNSSADVCLWQgitCNNSSrvVSIDLSGKNI--SGKISSAIFRlPYIQTINLSNNQLSGPIPDDIFTT 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 518 VSNVKYLDLSHNklDFDSDLAFSELTKLEVLDLSYNAHYFQIA---GVTHRLGF---------------IKNLTKLNILN 579
Cdd:PLN00113 117 SSSLRYLNLSNN--NFTGSIPRGSIPNLETLDLSNNMLSGEIPndiGSFSSLKVldlggnvlvgkipnsLTNLTSLEFLT 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 580 LSYNS-----------------IYtLTEYNLSSVSLQEL--VFSGNCLDQLWHAEDDRYNAIFKGLRNLTRLDLSYNKLQ 640
Cdd:PLN00113 195 LASNQlvgqiprelgqmkslkwIY-LGYNNLSGEIPYEIggLTSLNHLDLVYNNLTGPIPSSLGNLKNLQYLFLYQNKLS 273
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 641 -RIPDEAFvNLpQNLTELYINNNYLQFFNWSLLQQFVHLNLLDLSRNHLYFLTYSLSKFTPSLQTLLLSHNRIFHLPSGF 719
Cdd:PLN00113 274 gPIPPSIF-SL-QKLISLDLSDNSLSGEIPELVIQLQNLEILHLFSNNFTGKIPVALTSLPRLQVLQLWSNKFSGEIPKN 351
|
330
....*....|....*..
gi 1052247137 720 LSEARNLVHLDLSYNKL 736
Cdd:PLN00113 352 LGKHNNLTVLDLSTNNL 368
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
189-244 |
9.73e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 46.75 E-value: 9.73e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 1052247137 189 TNLKVLSLSFNNLSQVPHNLPRSLTNL---YLSNTNIHVIHRGDFKKLENLRVLDLSGN 244
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLkvlDLSNNLLTTLSPGAFSGLPSLRYLDLSGN 59
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
575-742 |
1.21e-06 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 52.78 E-value: 1.21e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 575 LNILNLSYNSIYTLTEYnLSSvSLQELVFSGNCLDQLWHAEDDrynaifkGLRNLtrlDLSYNKLQRIPDeafvNLPQNL 654
Cdd:PRK15370 243 IQEMELSINRITELPER-LPS-ALQSLDLFHNKISCLPENLPE-------ELRYL---SVYDNSIRTLPA----HLPSGI 306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 655 TELYINNNYLQFFNWSL---LQQFV---------------HLNLLDLSRNHLYFLTYSLSkftPSLQTLLLSHNRIFHLP 716
Cdd:PRK15370 307 THLNVQSNSLTALPETLppgLKTLEagenaltslpaslppELQVLDVSKNQITVLPETLP---PTITTLDVSRNALTNLP 383
|
170 180
....*....|....*....|....*.
gi 1052247137 717 SGFLSEarnLVHLDLSYNKLQTINRS 742
Cdd:PRK15370 384 ENLPAA---LQIMQASRNNLVRLPES 406
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
43-345 |
1.90e-06 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 52.16 E-value: 1.90e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 43 EVPKGVSKY--VTELDLSSNFITLITNESFRGLGNLTKINLNHNVV---LPPYIEnhytnkngltitdgaffDLQNLTEL 117
Cdd:PLN00113 347 EIPKNLGKHnnLTVLDLSTNNLTGEIPEGLCSSGNLFKLILFSNSLegeIPKSLG-----------------ACRSLRRV 409
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 118 LLEDNQLNkipANLPRSLKTLSLIqnNIVFITENNTSGlgNLETLylGWncyfgnacnqtfclsnrtfkETTNLKVLSLS 197
Cdd:PLN00113 410 RLQDNSFS---GELPSEFTKLPLV--YFLDISNNNLQG--RINSR--KW--------------------DMPSLQMLSLA 460
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 198 FNNLSQvphNLPrsltnlylsntnihvihrgDFKKLENLRVLDLSGNCpkcFNAPFPctpcpggasividnLAFHDLSNL 277
Cdd:PLN00113 461 RNKFFG---GLP-------------------DSFGSKRLENLDLSRNQ---FSGAVP--------------RKLGSLSEL 501
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1052247137 278 QILNLSSTSLRKIPATWFDKMHHLKELYLQFNNLAQEIMSGdfLAKLPVLEILDLSFNYIKGDYPANI 345
Cdd:PLN00113 502 MQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQLSGQIPAS--FSEMPVLSQLDLSQNQLSGEIPKNL 567
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
265-311 |
1.99e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 45.98 E-value: 1.99e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 1052247137 265 VIDNLAFHDLSNLQILNLSSTSLRKIPATWFDKMHHLKELYLQFNNL 311
Cdd:pfam13855 15 SLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
499-553 |
2.22e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 45.59 E-value: 2.22e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 1052247137 499 LNLSSNdNAQALNGTEFSAVSNVKYLDLSHNKLDFDSDLAFSELTKLEVLDLSYN 553
Cdd:pfam13855 6 LDLSNN-RLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGN 59
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
623-664 |
2.26e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 45.59 E-value: 2.26e-06
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 1052247137 623 FKGLRNLTRLDLSYNKLQRIPDEAFVNLPqNLTELYINNNYL 664
Cdd:pfam13855 21 FKGLSNLKVLDLSNNLLTTLSPGAFSGLP-SLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
52-124 |
2.92e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 45.59 E-value: 2.92e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1052247137 52 VTELDLSSNFITLITNESFRGLGNLTKINLNHNvvlppyienhytnkNGLTITDGAFFDLQNLTELLLEDNQL 124
Cdd:pfam13855 3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNN--------------LLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
210-419 |
3.72e-06 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 49.01 E-value: 3.72e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 210 RSLTNLYLSNTNIHVIhrGDFKKLENLRVLDLSGNCPKCfnapfpctpcpggasivIDNLAFhdLSNLQILNLSSTSLRK 289
Cdd:cd21340 2 KRITHLYLNDKNITKI--DNLSLCKNLKVLYLYDNKITK-----------------IENLEF--LTNLTHLYLQNNQIEK 60
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 290 IPAtwFDKMHHLKELYLQFNNLAqeIMSGdfLAKLPVLEILDLSFNYIKGDYPANINISSKFINLKSLRELHLEGyvfqe 369
Cdd:cd21340 61 IEN--LENLVNLKKLYLGGNRIS--VVEG--LENLTNLEELHIENQRLPPGEKLTFDPRSLAALSNSLRVLNISG----- 129
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1052247137 370 LRQKDLEPLANLSNLTTINLGVNFIKQID--FTFFRNHRNLKVVYLSLNRIS 419
Cdd:cd21340 130 NNIDSLEPLAPLRNLEQLDASNNQISDLEelLDLLSSWPSLRELDLTGNPVC 181
|
|
| LRRCT |
smart00082 |
Leucine rich repeat C-terminal domain; |
760-800 |
3.75e-06 |
|
Leucine rich repeat C-terminal domain;
Pssm-ID: 214507 [Multi-domain] Cd Length: 51 Bit Score: 44.73 E-value: 3.75e-06
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 1052247137 760 NPFDCTCDLGDFRRWMDENlhVRIPRLAAITCDSPGNQRGK 800
Cdd:smart00082 1 NPFICDCELRWLLRWLQAN--EHLQDPVDLRCASPSSLRGP 39
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
40-218 |
1.43e-05 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 49.31 E-value: 1.43e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 40 DLREVPKGVSKYVTELDLSSNFITLITNesfRGLGNLTKINLNHNVV--LPPyienhytnknglTITDGaffdlqnLTEL 117
Cdd:PRK15370 231 QLTSIPATLPDTIQEMELSINRITELPE---RLPSALQSLDLFHNKIscLPE------------NLPEE-------LRYL 288
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 118 LLEDNQLNKIPANLPRSLKTLSLIQNNIVFITENNTSglgNLETLYLGWNCYfgnacnqtFCLSNRTFKEttnLKVLSLS 197
Cdd:PRK15370 289 SVYDNSIRTLPAHLPSGITHLNVQSNSLTALPETLPP---GLKTLEAGENAL--------TSLPASLPPE---LQVLDVS 354
|
170 180
....*....|....*....|.
gi 1052247137 198 FNNLSQVPHNLPRSLTNLYLS 218
Cdd:PRK15370 355 KNQITVLPETLPPTITTLDVS 375
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
629-739 |
2.24e-05 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 48.54 E-value: 2.24e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 629 LTRLDLSYNKLQRIPDeafvNLPQNLTELYINNNYLQFFNWSLLQQfvhLNLLDLSRNHLYFLTYSLskftPS-LQTLLL 707
Cdd:PRK15370 201 ITTLILDNNELKSLPE----NLQGNIKTLYANSNQLTSIPATLPDT---IQEMELSINRITELPERL----PSaLQSLDL 269
|
90 100 110
....*....|....*....|....*....|..
gi 1052247137 708 SHNRIFHLPSGFLSEARnlvHLDLSYNKLQTI 739
Cdd:PRK15370 270 FHNKISCLPENLPEELR---YLSVYDNSIRTL 298
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
700-745 |
3.17e-05 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 42.51 E-value: 3.17e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 1052247137 700 PSLQTLLLSHNRIFHLPSGFLSEARNLVHLDLSYNKLQTINRSTLQ 745
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFS 46
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
43-354 |
3.41e-05 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 47.92 E-value: 3.41e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 43 EVPKGVSKYVT--ELDLSSNFITLITNESFRGLGNLTKINLNHNVV---LPPYIenhytnkngltitdgafFDLQNLTEL 117
Cdd:PLN00113 227 EIPYEIGGLTSlnHLDLVYNNLTGPIPSSLGNLKNLQYLFLYQNKLsgpIPPSI-----------------FSLQKLISL 289
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 118 LLEDNQLN-KIPANLP--RSLKTLSLIQNNIVFITENNTSGLGNLETLYLGWNCYFGNAcnqtfclsNRTFKETTNLKVL 194
Cdd:PLN00113 290 DLSDNSLSgEIPELVIqlQNLEILHLFSNNFTGKIPVALTSLPRLQVLQLWSNKFSGEI--------PKNLGKHNNLTVL 361
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 195 SLSFNNLS-QVPHNLPRS--LTNLYL-SNTNIHVIHR--GDFKKLENLRVLD--LSGNCPKCFNApfpcTPCPGGASIVI 266
Cdd:PLN00113 362 DLSTNNLTgEIPEGLCSSgnLFKLILfSNSLEGEIPKslGACRSLRRVRLQDnsFSGELPSEFTK----LPLVYFLDISN 437
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 267 DNLAFH------DLSNLQILNLSSTS-LRKIPATWFDKmhHLKELYLQFNNLAQEIMSGdfLAKLPVLEILDLSFNYIKG 339
Cdd:PLN00113 438 NNLQGRinsrkwDMPSLQMLSLARNKfFGGLPDSFGSK--RLENLDLSRNQFSGAVPRK--LGSLSELMQLKLSENKLSG 513
|
330
....*....|....*
gi 1052247137 340 DYPANINISSKFINL 354
Cdd:PLN00113 514 EIPDELSSCKKLVSL 528
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
518-736 |
9.93e-05 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 45.81 E-value: 9.93e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 518 VSNVKYLDLSHNKLDFDSDLA-FSELTK---LEVLDLSYNAHYFQIAGVTHRLGFIKNLTKLNILNLSYNSIYTLT---- 589
Cdd:cd00116 22 LLCLQVLRLEGNTLGEEAAKAlASALRPqpsLKELCLSLNETGRIPRGLQSLLQGLTKGCGLQELDLSDNALGPDGcgvl 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 590 EYNLSSVSLQELVFSGNcldqlwhAEDDRYNAIF-KGLR----NLTRLDLSYNKLQRIPDEAFVN-LPQN--LTELYINN 661
Cdd:cd00116 102 ESLLRSSSLQELKLNNN-------GLGDRGLRLLaKGLKdlppALEKLVLGRNRLEGASCEALAKaLRANrdLKELNLAN 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 662 NYLQFFNWSLLQQ----FVHLNLLDLSRNHL-----YFLTYSLSKfTPSLQTLLLSHNRI-----FHLPSGFLSEARNLV 727
Cdd:cd00116 175 NGIGDAGIRALAEglkaNCNLEVLDLNNNGLtdegaSALAETLAS-LKSLEVLNLGDNNLtdagaAALASALLSPNISLL 253
|
....*....
gi 1052247137 728 HLDLSYNKL 736
Cdd:cd00116 254 TLSLSCNDI 262
|
|
| PLN03150 |
PLN03150 |
hypothetical protein; Provisional |
280-364 |
1.16e-04 |
|
hypothetical protein; Provisional
Pssm-ID: 178695 [Multi-domain] Cd Length: 623 Bit Score: 45.96 E-value: 1.16e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 280 LNLSSTSLR-KIPATWfDKMHHLKELYLQFNNLAQEIMSGdfLAKLPVLEILDLSFNYIKGDYPANINisskfiNLKSLR 358
Cdd:PLN03150 423 LGLDNQGLRgFIPNDI-SKLRHLQSINLSGNSIRGNIPPS--LGSITSLEVLDLSYNSFNGSIPESLG------QLTSLR 493
|
....*.
gi 1052247137 359 ELHLEG 364
Cdd:PLN03150 494 ILNLNG 499
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
677-736 |
2.73e-04 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 39.82 E-value: 2.73e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 677 HLNLLDLSRNHLYFLTYSLSKFTPSLQTLLLSHNRIFHLPSGFLSEARNLVHLDLSYNKL 736
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
40-157 |
3.56e-04 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 44.69 E-value: 3.56e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 40 DLREVPKGVSKYVTELDLSSNFITLITNESFRGLGNLTKinlNHNVV------LPPYIENHYTNKNGLTITDGAFfdLQN 113
Cdd:PRK15370 294 SIRTLPAHLPSGITHLNVQSNSLTALPETLPPGLKTLEA---GENALtslpasLPPELQVLDVSKNQITVLPETL--PPT 368
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 1052247137 114 LTELLLEDNQLNKIPANLPRSLKTLSLIQNNIVFITENNTSGLG 157
Cdd:PRK15370 369 ITTLDVSRNALTNLPENLPAALQIMQASRNNLVRLPESLPHFRG 412
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
519-585 |
6.67e-04 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 38.66 E-value: 6.67e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1052247137 519 SNVKYLDLSHNKLDFDSDLAFSELTKLEVLDLSYNahyfqiagvthRLGFI-----KNLTKLNILNLSYNSI 585
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNN-----------LLTTLspgafSGLPSLRYLDLSGNRL 61
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
474-639 |
8.48e-04 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 42.73 E-value: 8.48e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 474 LDLSLNNIFFIGQKQFEAFQNEIACLNLSSNDNAQALNGTEFSAVS------NVKYLDLSHNKLDFDS--DLA--FSELT 543
Cdd:cd00116 86 LDLSDNALGPDGCGVLESLLRSSSLQELKLNNNGLGDRGLRLLAKGlkdlppALEKLVLGRNRLEGASceALAkaLRANR 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 544 KLEVLDLSYNAhyFQIAGVTHRLGFIKNLTKLNILNLSYNSI---------------YTLTEYNLS-------------- 594
Cdd:cd00116 166 DLKELNLANNG--IGDAGIRALAEGLKANCNLEVLDLNNNGLtdegasalaetlaslKSLEVLNLGdnnltdagaaalas 243
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1052247137 595 -----SVSLQELVFSGNCLdqlwhaEDDRYNAIFKGLRN---LTRLDLSYNKL 639
Cdd:cd00116 244 allspNISLLTLSLSCNDI------TDDGAKDLAEVLAEkesLLELDLRGNKF 290
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
524-662 |
1.09e-03 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 41.70 E-value: 1.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 524 LDLSHNKLDFDSDLafSELTKLEVLDLSYNahyfQIAGVTHrLGFIKNLTKLNILN----------LSYNSIYTLteynl 593
Cdd:cd21340 51 LYLQNNQIEKIENL--ENLVNLKKLYLGGN----RISVVEG-LENLTNLEELHIENqrlppgekltFDPRSLAAL----- 118
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1052247137 594 sSVSLQELVFSGNCLDQLwhaeddrynAIFKGLRNLTRLDLSYNKLQRIPD--EAFVNLPQnLTELYINNN 662
Cdd:cd21340 119 -SNSLRVLNISGNNIDSL---------EPLAPLRNLEQLDASNNQISDLEEllDLLSSWPS-LRELDLTGN 178
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
112-167 |
3.32e-03 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 36.73 E-value: 3.32e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 112 QNLTELLLEDNQLNKIPA----NLPrSLKTLSLIQNNIVFITENNTSGLGNLETLYLGWN 167
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDgafkGLS-NLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGN 59
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
53-168 |
3.81e-03 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 40.15 E-value: 3.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 53 TELDLSSNFITLITNesFRGLGNLTKINLNHN---VVlppyienhytnkNGLTitdgaffDLQNLTELLLEDNQL----- 124
Cdd:cd21340 49 THLYLQNNQIEKIEN--LENLVNLKKLYLGGNrisVV------------EGLE-------NLTNLEELHIENQRLppgek 107
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 1052247137 125 ----NKIPANLPRSLKTLSLIQNNIVFITEnnTSGLGNLETLYLGWNC 168
Cdd:cd21340 108 ltfdPRSLAALSNSLRVLNISGNNIDSLEP--LAPLRNLEQLDASNNQ 153
|
|
| PLN03150 |
PLN03150 |
hypothetical protein; Provisional |
496-585 |
6.80e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 178695 [Multi-domain] Cd Length: 623 Bit Score: 40.18 E-value: 6.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052247137 496 IACLNLssnDNaQALNG---TEFSAVSNVKYLDLSHNKLDFDSDLAFSELTKLEVLDLSYNahyfQIAG-VTHRLGfikN 571
Cdd:PLN03150 420 IDGLGL---DN-QGLRGfipNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYN----SFNGsIPESLG---Q 488
|
90
....*....|....
gi 1052247137 572 LTKLNILNLSYNSI 585
Cdd:PLN03150 489 LTSLRILNLNGNSL 502
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
300-364 |
7.30e-03 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 35.96 E-value: 7.30e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1052247137 300 HLKELYLQFNNLAQeiMSGDFLAKLPVLEILDLSFNYIKGDYPANinisskFINLKSLRELHLEG 364
Cdd:pfam13855 2 NLRSLDLSNNRLTS--LDDGAFKGLSNLKVLDLSNNLLTTLSPGA------FSGLPSLRYLDLSG 58
|
|
| LRR |
smart00370 |
Leucine-rich repeats, outliers; |
626-647 |
8.27e-03 |
|
Leucine-rich repeats, outliers;
Pssm-ID: 197688 [Multi-domain] Cd Length: 24 Bit Score: 34.63 E-value: 8.27e-03
|
| LRR_TYP |
smart00369 |
Leucine-rich repeats, typical (most populated) subfamily; |
626-647 |
8.27e-03 |
|
Leucine-rich repeats, typical (most populated) subfamily;
Pssm-ID: 197687 [Multi-domain] Cd Length: 24 Bit Score: 34.63 E-value: 8.27e-03
|
| |
