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Conserved domains on  [gi|1112922290|gb|API84859|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Gadus morhua]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475913)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-347 0e+00

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 536.31  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290   1 MNPFILSILLLSLGLGTTLTFASSHWLLAWMGLEISTLAIIPLMSQHHHPRAVEATTKYFITQAAAAALILFASTTNAWI 80
Cdd:MTH00135    1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290  81 TGQWDINFDLHFFPASMLTMALALKMGLAPVHFWLPEVLQGLDLTTGLILSTWQKLAPFILMCQIMPVNSSLITFLGVTS 160
Cdd:MTH00135   81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPTNPTLLITLGLTS 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMILVMQFNQQLALLALIIYIPMTFSTFMIFKTNSSTTVNTLAASWAKTPALT 240
Cdd:MTH00135  161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALT 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 241 AITPMILLSLGGLPPLSGFMPKWMILQELTKQDIPLTASIAALSALLSLYFYLRVSYAMTLTISPNNLNATTPWRLQTTA 320
Cdd:MTH00135  241 ALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPSTQ 320

                         330       340
                  ....*....|....*....|....*..
gi 1112922290 321 STLPLAISATISAMLLPLAPATLALLS 347
Cdd:MTH00135  321 LTLPLAISTTATLMLLPLTPAILALLT 347
 
Name Accession Description Interval E-value
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-347 0e+00

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 536.31  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290   1 MNPFILSILLLSLGLGTTLTFASSHWLLAWMGLEISTLAIIPLMSQHHHPRAVEATTKYFITQAAAAALILFASTTNAWI 80
Cdd:MTH00135    1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290  81 TGQWDINFDLHFFPASMLTMALALKMGLAPVHFWLPEVLQGLDLTTGLILSTWQKLAPFILMCQIMPVNSSLITFLGVTS 160
Cdd:MTH00135   81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPTNPTLLITLGLTS 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMILVMQFNQQLALLALIIYIPMTFSTFMIFKTNSSTTVNTLAASWAKTPALT 240
Cdd:MTH00135  161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALT 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 241 AITPMILLSLGGLPPLSGFMPKWMILQELTKQDIPLTASIAALSALLSLYFYLRVSYAMTLTISPNNLNATTPWRLQTTA 320
Cdd:MTH00135  241 ALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPSTQ 320

                         330       340
                  ....*....|....*....|....*..
gi 1112922290 321 STLPLAISATISAMLLPLAPATLALLS 347
Cdd:MTH00135  321 LTLPLAISTTATLMLLPLTPAILALLT 347
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-267 1.84e-20

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 89.68  E-value: 1.84e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290  23 SSHWLLAWMGLEISTLAIIPLM-SQHHHPRAVEATTKYFITQAAAAALILFASTTNAWITGQWDI-----------NFDL 90
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFdelskaltgglNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290  91 HFFPASMLTMALALKMGLAPVHFWLPEVLQGLDLTTGLIL-STWQKLAPFILMCQIMPVNSS------LITFLGVTSTLV 163
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLaATLVKAGGYGLIRRSLLYLPSspfiqqILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 164 GGWGGLNQTQLRKILAYSSIAHLGWMILVM----QFNQQLALLALIIYIPMTFSTF-----MIFKTNSSTTVNTLAASWA 234
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFlcagsVIYRRVHTRNIRDYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 1112922290 235 KTPALTAITPMILLSLGGLPPLSGFMPKWMILQ 267
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 22-299 1.97e-17

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 82.86  E-value: 1.97e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290  22 ASSHWLLAWMGLEISTLAIIPLMS-QHHHPRAVEATTKYFITQAAAAALILF--------ASTTN-----AWITGQWDIN 87
Cdd:COG1007   120 SANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgisllygaTGSLNlagiaAALAAGGANS 199

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290  88 FdLHFFPASMLTMALALKMGLAPVHFWLPEVLQGLDLTTGLILSTWQKLAPFILMCQIM--------PVNSSLITFLGVT 159
Cdd:COG1007   200 P-LLLLGLVLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLRLLveafpglaADWQLLLAVLAVL 278

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVM----QFNQQLALLALIIYIPMTFSTFMIF-----KTNSSTTVNTLA 230
Cdd:COG1007   279 SMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLaagtPLGVSAALFYLLAYLFMNLGAFAVIlllsrKGGEAEEIEDLA 358

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1112922290 231 ASWAKTPALTAITPMILLSLGGLPPLSGFMPKWMILQELTKQDIPLTASIAALSALLSLYFYLRVSYAM 299
Cdd:COG1007   359 GLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRVVKAM 427
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 23-329 4.37e-17

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 81.92  E-value: 4.37e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290  23 SSHWLLAWMGLEISTLAIIPLMS-QHHHPRAVEATTKYFITQAAAAALILFASTTNAWITGQWDINFDLHFFPASMLT-- 99
Cdd:TIGR01770 121 SNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLLFLSNGMLNis 200

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 100 ----------MALALKMGLAPVHFWLPEVLQGLDLTTGLILSTWQKLAPFILMCQIM--------PVNSSLITFLGVTST 161
Cdd:TIGR01770 201 llllgivlilVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFlyilfgfsEAWQIFLAIIAFLSM 280

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 162 LVGGWGGLNQTQLRKILAYSSIAHLGWMILV----MQFNQQLALLALIIYIPMTFSTFMIF------KTNSSTTVNTLAA 231
Cdd:TIGR01770 281 LIGNFGALAQKKVKRLLAYSSISHVGYILIGllagTLEGIKAVLFYIFIYALMSLGAFGVLsllrsyKDEWIEYISDFAG 360

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 232 SWAKTPALTAITPMILLSLGGLPPLSGFMPKWMILQELTKQDIPLTASIAALSALLSLYFYLRVSYAMTLtispNNLNAT 311
Cdd:TIGR01770 361 LFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVVKVMYF----DKPERR 436

                         330
                  ....*....|....*...
gi 1112922290 312 TPWRLQTTASTLPLAISA 329
Cdd:TIGR01770 437 IPSNPQSKAQSLLLSISA 454
 
Name Accession Description Interval E-value
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-347 0e+00

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 536.31  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290   1 MNPFILSILLLSLGLGTTLTFASSHWLLAWMGLEISTLAIIPLMSQHHHPRAVEATTKYFITQAAAAALILFASTTNAWI 80
Cdd:MTH00135    1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290  81 TGQWDINFDLHFFPASMLTMALALKMGLAPVHFWLPEVLQGLDLTTGLILSTWQKLAPFILMCQIMPVNSSLITFLGVTS 160
Cdd:MTH00135   81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPTNPTLLITLGLTS 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMILVMQFNQQLALLALIIYIPMTFSTFMIFKTNSSTTVNTLAASWAKTPALT 240
Cdd:MTH00135  161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALT 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 241 AITPMILLSLGGLPPLSGFMPKWMILQELTKQDIPLTASIAALSALLSLYFYLRVSYAMTLTISPNNLNATTPWRLQTTA 320
Cdd:MTH00135  241 ALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPSTQ 320

                         330       340
                  ....*....|....*....|....*..
gi 1112922290 321 STLPLAISATISAMLLPLAPATLALLS 347
Cdd:MTH00135  321 LTLPLAISTTATLMLLPLTPAILALLT 347
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-346 5.84e-133

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 382.73  E-value: 5.84e-133
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290   1 MNPFILSILLLSLGLGTTLTFASSHWLLAWMGLEISTLAIIPLMSQHHHPRAVEATTKYFITQAAAAALILFASTTNAWI 80
Cdd:MTH00070    1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290  81 TGQWDINFDLHFFPASMLTMALALKMGLAPVHFWLPEVLQGLDLTTGLILSTWQKLAPFILMCQIMP-VNSSLITFLGVT 159
Cdd:MTH00070   81 TGEWTIMNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHlLNSNLLIIMGLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVMQFNQQLALLALIIYIPMTFSTFMIFKTNSSTTVNTLAASWAKTPAL 239
Cdd:MTH00070  161 STLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 240 TAITPMILLSLGGLPPLSGFMPKWMILQELTKQDIPLTASIAALSALLSLYFYLRVSYAMTLTISPNNLNATTPWRLQTT 319
Cdd:MTH00070  241 TSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRFKNK 320

                         330       340
                  ....*....|....*....|....*..
gi 1112922290 320 aSTLPLAISATISAMLLPLAPATLALL 346
Cdd:MTH00070  321 -TNNLLSLTIILSLMLLPITPTILNLF 346
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 7.26e-114

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 334.10  E-value: 7.26e-114
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290   1 MNPFILSILLLSLGLGTTLTFASSHWLLAWMGLEISTLAIIPLMSQHHHPRAVEATTKYFITQAAAAALILFASTTNAWI 80
Cdd:MTH00112    1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290  81 TGQWDINFDLHFFPASMLTMALALKMGLAPVHFWLPEVLQGLDLTTGLILSTWQKLAPFILMCQIMP-VNSSLITFLGVT 159
Cdd:MTH00112   81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNsLNPTLLLTLAIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVMQFNQQLALLALIIYIPMTFSTFMIFKTNSSTTVNTLAASWAKTPAL 239
Cdd:MTH00112  161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 240 TAITPMILLSLGGLPPLSGFMPKWMILQELTKQDIPLTASIAALSALLSLYFYLRVSYAMTLTISPNNLNATTPWRLQTT 319
Cdd:MTH00112  241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                         330       340
                  ....*....|....*....|....*..
gi 1112922290 320 ASTLpLAISATISAMLLPLAPATLALL 346
Cdd:MTH00112  321 KNTL-TATLTTLSTLLLPLSPMILTII 346
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-345 9.35e-113

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 331.43  E-value: 9.35e-113
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290   1 MNPFILSILLLSLGLGTTLTFASSHWLLAWMGLEISTLAIIPLMSQHHHPRAVEATTKYFITQAAAAALILFASTTNAWI 80
Cdd:MTH00105    1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290  81 TGQWDINFDLHFFPASMLTMALALKMGLAPVHFWLPEVLQGLDLTTGLILSTWQKLAPFILMCQIMP-VNSSLITFLGVT 159
Cdd:MTH00105   81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPsINPNLLLTLAIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVMQFNQQLALLALIIYIPMTFSTFMIFKTNSSTTVNTLAASWAKTPAL 239
Cdd:MTH00105  161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 240 TAITPMILLSLGGLPPLSGFMPKWMILQELTKQDIPLTASIAALSALLSLYFYLRVSYAMTLTISPNNLNATTPWRLQTT 319
Cdd:MTH00105  241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                         330       340
                  ....*....|....*....|....*.
gi 1112922290 320 ASTLPLAISATISAMLLPLAPATLAL 345
Cdd:MTH00105  321 KPMTLLPTLIILSTMLLPLTPMLSIL 346
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-346 1.19e-98

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 295.72  E-value: 1.19e-98
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290   1 MNPFILSILLLSLGLGTTLTFASSHWLLAWMGLEISTLAIIPLMSQHHHPRAVEATTKYFITQAAAAALILFASTTNAWI 80
Cdd:MTH00200    1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290  81 TGQWDINFDLHFFPASMLTMALALKMGLAPVHFWLPEVLQGLDLTTGLILSTWQKLAPFILMCQIMP-VNSSLITFLGVT 159
Cdd:MTH00200   81 SGQWGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPaLNSNILLLLGLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVMQFNQQLALLALIIYIPMTFSTFMIFKTNSSTTVNTLAASWAKTPAL 239
Cdd:MTH00200  161 SVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPIL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 240 TAITPMILLSLGGLPPLSGFMPKWMILQELTKQDIPLTASIAALSALLSLYFYLRVSYAMTLTISPNNLNATTPWRLQTT 319
Cdd:MTH00200  241 SMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWRTKSN 320

                         330       340
                  ....*....|....*....|....*..
gi 1112922290 320 aSTLPLAISATISAMLLPLAPATLALL 346
Cdd:MTH00200  321 -SNLLVGLLLLLSILGLPLTPQLLFLF 346
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 21-348 1.76e-78

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 244.07  E-value: 1.76e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290  21 FASSHWLLAWMGLEISTLAIIPLMSQHHHPRAVEATTKYFITQAAAAALILFASTTNAWITGQWDINFDLHFFPASMLTM 100
Cdd:MTH00041   21 ISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWLSGSWSINGPLNTLSSIIITL 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 101 ALALKMGLAPVHFWLPEVLQGLDLTTGLILSTWQKLAPF-ILMCQIMPVNSSLITFLGVTSTLVGGWGGLNQTQLRKILA 179
Cdd:MTH00041  101 ALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLiLLISISNLLNSNILILCGILSVLVGGWGGLNQTQTRKILA 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 180 YSSIAHLGWMILVMQFNQQLALLALIIYIPMTFSTFMIFKTNSSTTVNTLAASWAKTPALTAITPMILLSLGGLPPLSGF 259
Cdd:MTH00041  181 FSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPISAFLFILSILSLGGLPPLTGF 260

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 260 MPKWMILQELTKQDIPLTASIAALSALLSLYFYLRVSYAMTLTISPNNLNATTPWRLQTTASTLPLAISATISAMLLPLA 339
Cdd:MTH00041  261 LNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHSISLFSWRNSGNITVYGVILSILSSISILGLL 340


                  ....*....
gi 1112922290 340 PATLALLSL 348
Cdd:MTH00041  341 LIPLFLSFL 349
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 20-307 5.06e-52

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 175.40  E-value: 5.06e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290  20 TFASSHWLLAWMGLEISTLAIIPLMSQHHHPRAVEATTKYFITQAAAAALILFASTTNAWItgqwdiNFDLHFFPASMLT 99
Cdd:MTH00160   21 SISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNMLN------LMLFNNISSMLIN 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 100 MALALKMGLAPVHFWLPEVLQGLDLTTGLILSTWQKLAPFILMCQIMpvNSSLITFLGVTSTLVGGWGGLNQTQLRKILA 179
Cdd:MTH00160   95 SSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLI--NNNFIIIIIILSAIIGAIGGLNQTSLRKILA 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 180 YSSIAHLGWMILVMQFNQQLALLALIIYIPMTFSTFMIFKTNSSTTVNTLAASWAKTPALTAITPMILLSLGGLPPLSGF 259
Cdd:MTH00160  173 YSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLLFLNLLSLGGLPPFLGF 252

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 1112922290 260 MPKWMILQELTKQDIPLTASIAALSALLSLYFYLRVSYAMTLTISPNN 307
Cdd:MTH00160  253 LPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKN 300
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 23-301 1.63e-48

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 165.83  E-value: 1.63e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290  23 SSHWLLAWMGLEISTLAIIPLMSQHHHPRAVEATTKYFITQAAAAALILFASTTNAWITGQWDInfdlhffpASMLTMAL 102
Cdd:MTH00144   23 SSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSWFS--------MSLLLLGL 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 103 ALKMGLAPVHFWLPEVLQGLDLTTGLILSTWQKLAPFILMCQIMPVNS--SLITFLGVTSTLVGGWGGLNQTQLRKILAY 180
Cdd:MTH00144   95 CLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWlaYLLCVISVLSALVGSIGGLNQTQVRALLAY 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 181 SSIAHLGWMILVMQFNQQLALLALIIYIPMTFSTFMIFKTNSSTTVNTLaaSWAKTPALTAITPMILLSLGG-LPPLSGF 259
Cdd:MTH00144  175 SSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDL--GSLKPSYKTGLSIISLLLSLGgLPPFLGF 252

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 1112922290 260 MPKWMILQELTKQDIPLTASIAALSALLSLYFYLRVSYAMTL 301
Cdd:MTH00144  253 CSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFL 294
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 20-340 8.95e-40

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 143.00  E-value: 8.95e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290  20 TFASSHWLLAWMGLEISTLAIIPLMSQHHHPRAVEATTKYFITQAAAAALILFASTTNAWITGQwdinfdLHFFPASMLT 99
Cdd:MTH00011   22 ALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTMMWSFPSL------LKNITALMLL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 100 MALALKMGLAPVHFWLPEVLQGLDLTTGLILSTWQKLAPFILMCQIMPVN-SSLITFLGVTSTLVGGWGGLNQTQLRKIL 178
Cdd:MTH00011   96 VSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNiLPMMTSMAAMSALAGGLGGMNQTQLRPLL 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 179 AYSSIAHLGWMILVMQFNQQLALLALIIYIPMTFSTFMIFKTNSSTTVNTLAASWAKTPALTAITPMILLSLGGLPPLSG 258
Cdd:MTH00011  176 AYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLFIMLLSLGGLPPFTG 255

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 259 FMPKWMILQELTKQDIPLTASIAALSALLSLYFYLRVSYAMTlTISPNNLNattpwrLQTTASTLPLAISATISAMLLPL 338
Cdd:MTH00011  256 FMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFNFM-YLSPTFSS------LKSAPYEPKTKILISMCTLSLGL 328


                  ..
gi 1112922290 339 AP 340
Cdd:MTH00011  329 IP 330
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 22-297 6.23e-37

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 135.18  E-value: 6.23e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290  22 ASSHWLLAWMGLEISTLAIIPLMSQHHHPRAVEATTKYFITQAAAAALILFasttnawitGQWDINFDLHFFPAS--MLT 99
Cdd:MTH00197   16 SSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLM---------GGSLSFSNLYLSLLSvvLVI 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 100 MALALKMGLAPVHFWLPEVLQGLDLTTGLILSTWQKLAPFILMCQIMPvNSSLITFLGVTSTLVGGWGGLNQTQLRKILA 179
Cdd:MTH00197   87 LGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFNSS-SFMGLLICSVLSSLIGGIGGMNQSNIRQLLA 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 180 YSSIAHLGWMILVMQFNQQLALLALIIYIPMTFSTFMIFKTNSSTTVNTLaASWAKTPALTAITPMILLSLGG-LPPLSG 258
Cdd:MTH00197  166 YSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQ-YSNPESMSSNLVFLGLSFLSLGgLPPLSG 244

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 1112922290 259 FMPKWMILQELTKQDIPLTASIAALSALLSLYFYLRVSY 297
Cdd:MTH00197  245 FFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAY 283
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 23-295 1.21e-23

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 100.10  E-value: 1.21e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290  23 SSHWLLAWMGLEISTLAIIPLMSQHHHP-RAVEATTKYFITQAAAAALILFASTTNAWITGQWDINF-DLHFFPA----- 95
Cdd:MTH00196   12 SSNWLSVYLAIELQTLSLFILIAQNRGSgYSAEAGLKYFVLGALSSGLFLFGCALLCGTTGGLHLSYiNLVLNSGqsfss 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290  96 -------SMLTMALALKMGLAPVHFWLPEVLQGLDLTTGLILSTWQKLAPFILMCQIMPvNSSLITFLGVTSTLVGGWGG 168
Cdd:MTH00196   92 vsvpigyLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGL-NVNILLIGGLFSLFVGAIGA 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 169 LNQTQLRKILAYSSIAHLGWMILVMQFNQ----QLALLALIIYIPMTFSTFMI---FKTNSSTTVNtLAASWAKTPALTA 241
Cdd:MTH00196  171 LNQTKIKRLLAYSGIGHMGFVLWGIEIGSfesiQASLVYLFIYIIMSICVFSIilaLNVYKNLIIE-FSGLSRRLPILAI 249

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1112922290 242 ITPMILLSLGGLPPLSGFMPKWMILQELTKQDIPLTASIAALSALLSLYFYLRV 295
Cdd:MTH00196  250 TLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRI 303
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-267 1.84e-20

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 89.68  E-value: 1.84e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290  23 SSHWLLAWMGLEISTLAIIPLM-SQHHHPRAVEATTKYFITQAAAAALILFASTTNAWITGQWDI-----------NFDL 90
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFdelskaltgglNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290  91 HFFPASMLTMALALKMGLAPVHFWLPEVLQGLDLTTGLIL-STWQKLAPFILMCQIMPVNSS------LITFLGVTSTLV 163
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLaATLVKAGGYGLIRRSLLYLPSspfiqqILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 164 GGWGGLNQTQLRKILAYSSIAHLGWMILVM----QFNQQLALLALIIYIPMTFSTF-----MIFKTNSSTTVNTLAASWA 234
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFlcagsVIYRRVHTRNIRDYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 1112922290 235 KTPALTAITPMILLSLGGLPPLSGFMPKWMILQ 267
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 23-295 2.63e-18

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 85.45  E-value: 2.63e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290  23 SSHWLLAWMGLEISTLAIIPLMS-QHHHPRAVEATTKYFITQAAAAALILFASTTNAWITGQWDINFDLHFFPAS----M 97
Cdd:MTH00199  116 SINWLSIYLAIELQTLTLFILVAlKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGETSIQGINSILTGDvgkiL 195

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290  98 LTMALALKMGLAPVHFWLPEVLQGLDLTTGLILSTWQKLAPFILMCQIMPVnSSLITFLGVTSTLVGGWGGLNQTQLRKI 177
Cdd:MTH00199  196 ITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPV-TNVVLICAVLSIIYGAIGALNQTKIKRL 274

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 178 LAYSSIAHLGWMILVMQFNQ----QLALLALIIYIPMTFSTFMI---FKTNSSTTVNTLAASwAKTPALTAITPMILLSL 250
Cdd:MTH00199  275 LAYSGIGHMGFILFGVAIGSfesiQASLIYMIIYVIMSICSFSIilsLKLTKGLIVEVSGLS-RKNPVIALTLALTFLSI 353

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 1112922290 251 GGLPPLSGFMPKWMILQELTKQDIPLTASIAALSALLSLYFYLRV 295
Cdd:MTH00199  354 AGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRV 398
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 22-299 1.97e-17

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 82.86  E-value: 1.97e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290  22 ASSHWLLAWMGLEISTLAIIPLMS-QHHHPRAVEATTKYFITQAAAAALILF--------ASTTN-----AWITGQWDIN 87
Cdd:COG1007   120 SANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgisllygaTGSLNlagiaAALAAGGANS 199

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290  88 FdLHFFPASMLTMALALKMGLAPVHFWLPEVLQGLDLTTGLILSTWQKLAPFILMCQIM--------PVNSSLITFLGVT 159
Cdd:COG1007   200 P-LLLLGLVLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLRLLveafpglaADWQLLLAVLAVL 278

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVM----QFNQQLALLALIIYIPMTFSTFMIF-----KTNSSTTVNTLA 230
Cdd:COG1007   279 SMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLaagtPLGVSAALFYLLAYLFMNLGAFAVIlllsrKGGEAEEIEDLA 358

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1112922290 231 ASWAKTPALTAITPMILLSLGGLPPLSGFMPKWMILQELTKQDIPLTASIAALSALLSLYFYLRVSYAM 299
Cdd:COG1007   359 GLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRVVKAM 427
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 23-329 4.37e-17

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 81.92  E-value: 4.37e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290  23 SSHWLLAWMGLEISTLAIIPLMS-QHHHPRAVEATTKYFITQAAAAALILFASTTNAWITGQWDINFDLHFFPASMLT-- 99
Cdd:TIGR01770 121 SNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLLFLSNGMLNis 200

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 100 ----------MALALKMGLAPVHFWLPEVLQGLDLTTGLILSTWQKLAPFILMCQIM--------PVNSSLITFLGVTST 161
Cdd:TIGR01770 201 llllgivlilVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFlyilfgfsEAWQIFLAIIAFLSM 280

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 162 LVGGWGGLNQTQLRKILAYSSIAHLGWMILV----MQFNQQLALLALIIYIPMTFSTFMIF------KTNSSTTVNTLAA 231
Cdd:TIGR01770 281 LIGNFGALAQKKVKRLLAYSSISHVGYILIGllagTLEGIKAVLFYIFIYALMSLGAFGVLsllrsyKDEWIEYISDFAG 360

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 232 SWAKTPALTAITPMILLSLGGLPPLSGFMPKWMILQELTKQDIPLTASIAALSALLSLYFYLRVSYAMTLtispNNLNAT 311
Cdd:TIGR01770 361 LFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVVKVMYF----DKPERR 436

                         330
                  ....*....|....*...
gi 1112922290 312 TPWRLQTTASTLPLAISA 329
Cdd:TIGR01770 437 IPSNPQSKAQSLLLSISA 454
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
22-343 9.80e-16

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 77.94  E-value: 9.80e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290  22 ASSHWLLAWMGLEISTLAIIPLMSQH-HHPRAVEATTKYFITQAAAAALILF--------ASTTN----AWITGQWDINF 88
Cdd:PRK05777  121 SANDLLTLFLGLELLSLPLYALAALRrDRRRSLEAAIKYFVLGALASGFLLYgmsllygaTGSLSfagiAKALADGSGNS 200

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290  89 DLHFFPASMLTMALALKMGLAPVHFWLPEVLQGLDLTTGLILSTWQKLAPFILMCQIM--------PVNSSLITFLGVTS 160
Cdd:PRK05777  201 LLLLFGLVFLLVGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAVLLRLLvvafgglsEDWQQVLAIIAIAS 280

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMILVMQFNQQLALLA----LIIYIPMTFSTF-----MIFKTNSSTTVNTLAA 231
Cdd:PRK05777  281 MLVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLAAGTAEGYSAvlfyLLAYLFMTLGAFgvislLRRKGGEAESISDFAG 360

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 232 SWAKTPALTAITPMILLSLGGLPPLSGFMPKWMILQELTKQDIPLTASIAALSALLSLYFYLRVSYAMTLTISPNNLNAT 311
Cdd:PRK05777  361 LSKRSPLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFYYLRVIKLMYFDEPPRDAPVN 440

                         330       340       350
                  ....*....|....*....|....*....|..
gi 1112922290 312 TPWRLQTTAstlpLAISATISaMLLPLAPATL 343
Cdd:PRK05777  441 WPLSAGGAV----LSVSALLV-LVLGIFPQPL 467
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 30-299 1.14e-14

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 74.41  E-value: 1.14e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290  30 WMGLEISTLAIIPLMSQHHHPRAVEATTKYFITQAAAAALILFASTTNAWITGQWD----------INFDLHFFPASMLT 99
Cdd:COG0651   133 FVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNmadlaarlaeLDPGLLLAAFALLL 212

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 100 MALALKMGLAPVHFWLPE-----------VLQGLDLTTGL--ILSTWQKLAPFILMCQIMPVnsslITFLGVTSTLVGGW 166
Cdd:COG0651   213 VGFGIKAALFPLHFWLPDaypaapspvsaLLSGLLTKVGVyaILRVLTLLFGADPALFLGTL----LLVLGLLTMLVGAL 288

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 167 GGLNQTQLRKILAYSSIAHLGWMILVMQFNQQLALLALIIYIPMT--------FSTFMIFKTNSSTTVNTLAASWAKTP- 237
Cdd:COG0651   289 GALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHLLNHalakallfLAAGAIERATGTRDLDKLGGLGKRMPl 368

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1112922290 238 ----------ALTAITPMILlslgglpplsgFMPKWMILQELTKQDIPLTASIAALSALLSLYFYLRVSYAM 299
Cdd:COG0651   369 taaafligalALAGLPPLSG-----------FVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAYFVRIFGRA 429
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 23-220 1.01e-11

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 66.04  E-value: 1.01e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290  23 SSHWLLAWMGLEISTLAIIPLMSQHHHPRAV---------EATTKYFITQAAAAALILFASTTNAWITGQ---------- 83
Cdd:MTH00198  207 SANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFGCALYFGFTGNegmlgtilsa 286

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290  84 ----WDINFDLHFFPASMLTMALALKMGLAPVHFWLPEVLQGLDLTTGLILSTWQKLAPFILMCQIMpVNSSLITFLGVT 159
Cdd:MTH00198  287 tletTNIELRQGSLGYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILLTSLV-ITSKLLLSVAII 365

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1112922290 160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVMQFNQQLALLA----LIIYIPMTFSTFMIFKT 220
Cdd:MTH00198  366 SLVVGAFGALNQTRIKRLLAYSGIGHIGFILIGVSAGTYESLQAswtyAVTYLVSALASFTVICT 430
NADH_dehy_S2_C pfam06444
NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region ...
 290-340 5.66e-11

NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region specific to the eukaryotic NADH dehydrogenase subunit 2 protein and is found in conjunction with pfam00361.


Pssm-ID: 461914 [Multi-domain]  Cd Length: 51  Bit Score: 57.27  E-value: 5.66e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1112922290 290 YFYLRVSYAMTLTISPNNLNATTPWRLQTTASTLPLAISATISAMLLPLAP 340
Cdd:pfam06444   1 FFYLRLSYSTTLTLFPNTNNSKMKWRFNSTKNTLLLPTLTTLSILLLPLTP 51
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-345 1.23e-08

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 56.04  E-value: 1.23e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290  33 LEISTLAIIPLMSQHHHPRAVEATTKYFITQAAAAALILFASTTNAWITGQWDINFDLHFFPAS--------MLTMALAL 104
Cdd:PRK08375  135 LEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGVGLLYGVTGTLNMADLAGALAENptvvtafgFVLLALAL 214

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 105 KMGLAPVHFWLPEVLQGLDLTTGLILSTWQKLAPFILMCQIM-----------PVNSSLITFLGVTSTLVGGWGGLNQTQ 173
Cdd:PRK08375  215 KAAVFPLHTWLPRAYPAAPPVVTALLSGLVTKVAVYALIRIYftvfggdfrfaLGLGWLLAVLALLSMLVGSLAALGQDD 294

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 174 LRKILAYSSIAHLGWMILVMQFNQQLALLALIIYIP--------MTFSTFMIFKTNSSTTVNTLAASWAKTPALTAITPM 245
Cdd:PRK08375  295 VKRVLAYSTVSQMGYILLGLALLTPLALAAGLLHLLhhalmkgaLFLAAGAIEVTYGTRRLSELSGLGRRMPLTAAAFAV 374

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 246 ILLSLGGLPPLSGFMPKWMILQELTKQDIPLTASIAALSALLSLYFYLRVSYAMTLTISPNnlNATTPWRLQTTASTLPL 325
Cdd:PRK08375  375 ASLSLIGVPPTSGFVSKWYLVVGAVEAGQWLVLAVLLASSLLALLYFLRIWYRAFFGPPPP--GSEAPKQEAPLGMLAPS 452

                         330       340
                  ....*....|....*....|
gi 1112922290 326 AISATISAMLLPLAPATLAL 345
Cdd:PRK08375  453 LALALLSLLLGIYAGPLLQL 472
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 93-299 5.23e-08

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 54.21  E-value: 5.23e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290  93 FPASMLTMALAL-----KMGLAPVHFWLPEV-----------LQGLDLTTG---------LILSTWQKLAPFILMCQImp 147
Cdd:PRK12667  219 PLALGVALALALwaftiKAAIFPNHFWLPDAhpaapspvsamLSGLVVNVGayaiirflyTIFGISPSLIDFRAALSP-- 296

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 148 vnssLITFLGVTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMILVMQFNQQLALLALIIYI-------PMTF-STFMIFK 219
Cdd:PRK12667  297 ----ILIILGAVSAIIGALMMVVQKDVKRLLAYSTISHMGYIFMGIGIGTQLGLAAALFHIinhaiakSLLFlASGVFIH 372

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 220 TNSSTTVNTLAASWAKTPALTAITPMILLSLGGLPPLSGFMPKWMILQELTKQDIPLTASIAALSALLSLYFYLRVSYAM 299
Cdd:PRK12667  373 AAGTRDIDELAGLGRKMPIASFAFLIGALSLVGIPPLNGFFSKLLLFNALLESGFYLPALVLLIASAISLVGYFRAWYSL 452
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 101-207 2.29e-05

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 46.09  E-value: 2.29e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 101 ALALKMGLAPVHFWLPEV-LQGLDLTTGLILSTWQKLAPFILMCQIMPV--NSS-----LITFLGVTSTLVGGWGGLNQT 172
Cdd:TIGR01972 212 AFAVKVPLFPLHTWLPDAhVEAPTAGSVILAGVLLKMGTYGFLRFNLPLfpDASlyfapVLAALGVIAIIYGALIALAQT 291

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1112922290 173 QLRKILAYSSIAHLGWMILVMQFNQQLALLALIIY 207
Cdd:TIGR01972 292 DIKRLIAYSSISHMGFVLLGIFSFNELGISGAVFQ 326
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 49-191 5.10e-05

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 44.69  E-value: 5.10e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290  49 HPRAVEATTKYFITQAAAAALILFASTTNAWITGQWdiNFDL-----HFFPASM-------LTMALALKMGLAPVHFWLP 116
Cdd:COG1008   156 GERRIYAAIKFFLYTLAGSLLMLVAILALYFLAGAL--TFDIaelaaAPLPLTAqlllflaFFIAFAVKVPMFPFHTWLP 233

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 117 E-----------VLQGLDLTTG----------LILSTWQKLAPFILmcqimpvnsslitFLGVTSTLVGGWGGLNQTQLR 175
Cdd:COG1008   234 DahveaptagsvLLAGVLLKMGgygllrfalpLFPEASAYFAPLLA-------------ALGVIGIIYGALVALAQTDLK 300

                         170
                  ....*....|....*.
gi 1112922290 176 KILAYSSIAHLGWMIL 191
Cdd:COG1008   301 RLIAYSSVSHMGFVLL 316
PRK07376 PRK07376
NADH-quinone oxidoreductase subunit L;
110-193 1.87e-04

NADH-quinone oxidoreductase subunit L;


Pssm-ID: 236005 [Multi-domain]  Cd Length: 673  Bit Score: 43.09  E-value: 1.87e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 110 PVHFWLPEVLQGLDLTTGLILSTWQKLAPFILMCQIMPVNS------SLITFLGVTSTLVGGWGGLNQTQLRKILAYSSI 183
Cdd:PRK07376  245 PLHVWLPDAMEGPTPISALIHAATMVAAGVFLVARMYPVFEqfpavmTVIAWTGAITAFLGASIALTQNDIKKGLAYSTI 324

                          90
                  ....*....|
gi 1112922290 184 AHLGWMILVM 193
Cdd:PRK07376  325 SQLGYMVMAM 334
ND5 MTH00032
NADH dehydrogenase subunit 5; Provisional
 111-193 3.64e-04

NADH dehydrogenase subunit 5; Provisional


Pssm-ID: 214407 [Multi-domain]  Cd Length: 669  Bit Score: 42.25  E-value: 3.64e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 111 VHFWLPEVLQGLDLTTGLILSTWQKLAPFILMCQIMPVNSS------LITFLGVTSTLVGGWGGLNQTQLRKILAYSSIA 184
Cdd:MTH00032  244 LHTWLPDAMEGPTPVSALIHAATMVTAGVFLMIRSFPLFEKapltllIITIFGALTAFFAATVGLVQNDLKKVIAYSTCS 323


                  ....*....
gi 1112922290 185 HLGWMILVM 193
Cdd:MTH00032  324 QLGYMVLII 332
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 21-208 3.93e-04

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 42.05  E-value: 3.93e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290  21 FASSHWLLAWMGLEISTLAIIPLMSQHHHPRAVEATTKY-FITQAAAA-----ALILFASTTNAWITG--QWDINFDL-H 91
Cdd:PRK08676  119 FFSDNLALFWIFAELTTVFSAMLIAILSARENIDAALKYiFIASTAMIfafigLIFLFSLTRQALGTGtlNWTELAAHaS 198

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290  92 FFPASMLTMA-------LALKMGLAPVHFWLPE-----------VLQGLDLTTGLilstWQKLAPFILMCQ--IMPVNSS 151
Cdd:PRK08676  199 LLSPSVLGASflfifigFLAKSGLVPFHTWLPAayakapsvvsaLLSGTVLNIGI----YGILRLSALLRQsgAAEQFSN 274

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1112922290 152 LITFLGVTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMILVMQFNQQLALLALIIYI 208
Cdd:PRK08676  275 VLIGLGIFSIAVAAFSMLSQRNLKKLIAFSSIEHMGLMLLGIGIGTPLALFWMLFHM 331
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-191 3.99e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 42.01  E-value: 3.99e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290  33 LEISTLAIIPLMSQHHH-PRAVEATTKYFITQAAAAALILFA---------STTNAWITGQWDIN-FDLHFFPASMLTMA 101
Cdd:PRK08376  150 LEIMSIASYALVAFRNDtWEAIEAGIKYMFVGSLASSMVLLGiallygqygTLNMAYLAVKMSENpTVVAKIALALFIAG 229

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 102 LALKMGLAPVHFWLPEVLQGL--DLTTGLILSTWQKL-APFILMCQIMPVNSSL------ITFLGVTSTLVGGWGGLNQT 172
Cdd:PRK08376  230 LAMKSGAVPVHMWLPDAYPAApsSISAMLLVIKQAGLyALARVLFSIYGPAINLatvgwvIIILGCLTMFVGVAMAVVQK 309

                         170
                  ....*....|....*....
gi 1112922290 173 QLRKILAYSSIAHLGWMIL 191
Cdd:PRK08376  310 DVKRLLAYHSVSQIGYMLL 328
ndhB CHL00049
NADH dehydrogenase subunit 2
 98-295 5.62e-04

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 41.53  E-value: 5.62e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290  98 LTMALALKMGLAPVHFWLPEVLQGLDLTTGLILSTWQKLAPFILMCQIM----PVNS----SLITFLGVTSTLVGGWGGL 169
Cdd:CHL00049  220 ITVGIGFKLSLAPFHQWTPDVYEGSPTPVVAFLSVTSKVAASALATRIFdipfYFSSnewhLLLEILAILSMILGNLIAI 299

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 170 NQTQLRKILAYSSIAHLGWM---ILVMQFNQQLA--LLALIIYIPM---TFSTFMIFKTNSST-TVNTLAASWAKTPALT 240
Cdd:CHL00049  300 TQTSMKRMLAYSSIGQIGYViigIIVGDSNDGYAsmITYMLFYIFMnlgTFACIVLFGLRTGTdNIRDYAGLYTKDPFLA 379

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1112922290 241 AITPMILLSLGGLPPLSGFMPKWMILQELTKQDIPLTASIAALSALLSLYFYLRV 295
Cdd:CHL00049  380 LSLALCLLSLGGIPPLAGFFGKLYLFWCGWQAGLYFLVSIGLLTSVISIYYYLKI 434
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 147-191 1.38e-03

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 40.52  E-value: 1.38e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1112922290 147 PVNSSLITFLGVTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMIL 191
Cdd:COG1009   272 PVWLTVVAIIGAITALFAALIALAQTDIKRVLAYSTVSQLGYMFL 316
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
55-205 1.54e-03

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 40.07  E-value: 1.54e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290  55 ATTKYFITQAAAAALILFASTTNAWITGQWDINFD---LHFFPASM-------LTMALALKMGLAPVHFWLPE------- 117
Cdd:PRK06473  158 AATKFLLYTAISGILILVSFLGLVWLSGASSFDYEplrSHTLPLSTqllllapILVGFGIKIPLVPFHTWLPDahveast 237

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 118 ----VLQG--LDLTT--------GLILSTWQKLAPFIlmcqimpvnssliTFLGVTSTLVGGWGGLNQTQLRKILAYSSI 183
Cdd:PRK06473  238 pvsvLLAGvlLKLGTygllrfgvGLFPEAWVYLAPWL-------------ATWAVVSVLYGASCAIAQKDMKKMVAYSSI 304

                         170       180
                  ....*....|....*....|..
gi 1112922290 184 AHLGWMILVMQFNQQLALLALI 205
Cdd:PRK06473  305 GHMGYILLAAAAATPLSILAAV 326
PRK12648 PRK12648
putative monovalent cation/H+ antiporter subunit A; Reviewed
 152-208 1.72e-03

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237157 [Multi-domain]  Cd Length: 948  Bit Score: 40.17  E-value: 1.72e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1112922290 152 LITFLGVTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMILVMQFNQQLALLALIIYI 208
Cdd:PRK12648  273 IVGGAGLITLLLGAYFALFQHDLKGLLAYSTISHLGLITLLLGLGSPLAAVAAIFHI 329
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 28-206 5.99e-03

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 38.37  E-value: 5.99e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290  28 LAWMGLEISTLAIIPLMSQHHHPRAVEATTKYFI------TQAAAAALILFASTTNAWITGQWDINFDL------HFFPA 95
Cdd:PRK06458  132 LMWVAIEATTLSSALLVGIYRTRASLEAAWKYIIicsvgvAFALFGTILVYANAATVMGDGEMAILWTEllkhasLLDPT 211

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290  96 SM-LTMALAL-----KMGLAPVHFWLPE-----------VLQGLDLTTGLILstwqklapfILMCQI--------MPVNS 150
Cdd:PRK06458  212 LMkLAFVFLLigfgtKVGLFPMHAWLPDahseapspvsaLLSGVLLNVALYA---------VLRYYIlidaaigsDFPGR 282

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1112922290 151 SLITFlGVTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMILVMQFNQQLALLALII 206
Cdd:PRK06458  283 LLLIF-GLLSVLVAAFFLLRQRDIKRLFAYSSIEHMGLIAFALGIGGPLGIFAALL 337
PRK12644 PRK12644
putative monovalent cation/H+ antiporter subunit A; Reviewed
 152-203 6.89e-03

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237154 [Multi-domain]  Cd Length: 965  Bit Score: 38.37  E-value: 6.89e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1112922290 152 LITFLGVTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMILVMQFNQQLALLA 203
Cdd:PRK12644  269 TVLVLGLATMLLGGWRALRQHDLKLILAYGTVSQLGFLTVLVGIGTRDAALA 320
PRK12646 PRK12646
DUF4040 family protein;
91-193 8.57e-03

DUF4040 family protein;


Pssm-ID: 183646 [Multi-domain]  Cd Length: 800  Bit Score: 38.20  E-value: 8.57e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290  91 HFFPASMLTMALA--LKMGLAPVHFWLPEVLQGLDLTTGLILSTWQKLAPFILMCQIMPVNS------SLITFLGVTSTL 162
Cdd:PRK12646  207 GLFIPMIFMFLLGafTKSAQFPFHIWLPRAMAAPTPVSAYLHSATMVKAGIFLLFRFTPLLGlsnmyiYIVTFVGLITML 286

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1112922290 163 VGGWGGLNQTQLRKILAYSSIAHLGwMILVM 193
Cdd:PRK12646  287 FGSITALKQWDLKGILAYSTISQLG-MIMAM 316
PRK07363 PRK07363
NADH-quinone oxidoreductase subunit M;
55-202 8.78e-03

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 180945 [Multi-domain]  Cd Length: 501  Bit Score: 37.77  E-value: 8.78e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290  55 ATTKYFITQAAAAALILFASTTNAWITGQWDINFDLHF---FPASMLTMALAL-------KMGLAPVHFWLPEVLQGLDL 124
Cdd:PRK07363  158 ASIKFLIYTAVSGLLVLAAFLGIVWLSGSTSFDYDAIStqnLSLNTQLILLTGlllgfgiKIPLVPLHTWLPDAYTEASP 237

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112922290 125 TTGLILS-TWQKLAPFILM---CQIMPVNSSLIT----FLGVTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMILVMQFN 196
Cdd:PRK07363  238 AVAILLGgVLAKLGTYGLLrfgLQLFPQTWSLVApglaIIGTISVIYGALSAIAQKDIKRMVAYSSIGHMGYILVAAAAG 317


                  ....*.
gi 1112922290 197 QQLALL 202
Cdd:PRK07363  318 TQLSLL 323
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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