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Conserved domains on  [gi|1150920481|gb|AQR88362|]
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hypothetical protein GP2223_43260 [Bacillus subtilis subsp. subtilis str. 168]

Protein Classification

PH domain-containing protein( domain architecture ID 11975562)

pleckstrin homology (PH) domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
bPH_4 pfam06713
Bacterial PH domain; This family consists of several hypothetical proteins specific to ...
 61-136 7.10e-20

Bacterial PH domain; This family consists of several hypothetical proteins specific to Oceanobacillus and Bacillus species. Members of this family are typically around 130 residues in length. The function of this family is unknown. Members of this family have a PH domain like structure.


:

Pssm-ID: 369049  Cd Length: 74  Bit Score: 77.65  E-value: 7.10e-20
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1150920481  61 KYVLKEHHLIIKAGLIKHQIPYENIDKVVQKKKLWSgfRLIGSRHAITIYYqGGWGHAVISPQKSEEFIHKLKEKN 136
Cdd:pfam06713   2 KYILTEGTLIIKSGFFKKKIPIEDITKIRKTKSPLS--SPALSLDRLEIKY-GKYDTILISPKDKEEFIKLLKKRN 74
YdbT super family cl28701
Uncharacterized membrane protein YdbT, contains bPH2 (bacterial pleckstrin homology) domain ...
 1-85 9.01e-05

Uncharacterized membrane protein YdbT, contains bPH2 (bacterial pleckstrin homology) domain [Function unknown];


The actual alignment was detected with superfamily member COG3428:

Pssm-ID: 442654 [Multi-domain]  Cd Length: 410  Bit Score: 40.85  E-value: 9.01e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1150920481   1 MVYQTKRDVPVTLMIVFLILLIQADAIVPFVLGNMRVSG---WIIFILLTLLNGLIIWSFID---LKYVLKEHHLIIKAG 74
Cdd:COG3428     1 MSEPWRRLHPLSILVRLLKALALLLPVLLLLLAGVGAGGgllWVLLIALVLLLLLLLVSYLRwrtTRYRITDDRLIVRSG 80

                          90
                  ....*....|....
gi 1150920481  75 LI---KHQIPYENI 85
Cdd:COG3428    81 VLsrkRREIPLDRI 94
 
Name Accession Description Interval E-value
bPH_4 pfam06713
Bacterial PH domain; This family consists of several hypothetical proteins specific to ...
 61-136 7.10e-20

Bacterial PH domain; This family consists of several hypothetical proteins specific to Oceanobacillus and Bacillus species. Members of this family are typically around 130 residues in length. The function of this family is unknown. Members of this family have a PH domain like structure.


Pssm-ID: 369049  Cd Length: 74  Bit Score: 77.65  E-value: 7.10e-20
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1150920481  61 KYVLKEHHLIIKAGLIKHQIPYENIDKVVQKKKLWSgfRLIGSRHAITIYYqGGWGHAVISPQKSEEFIHKLKEKN 136
Cdd:pfam06713   2 KYILTEGTLIIKSGFFKKKIPIEDITKIRKTKSPLS--SPALSLDRLEIKY-GKYDTILISPKDKEEFIKLLKKRN 74
YdbT COG3428
Uncharacterized membrane protein YdbT, contains bPH2 (bacterial pleckstrin homology) domain ...
 1-85 9.01e-05

Uncharacterized membrane protein YdbT, contains bPH2 (bacterial pleckstrin homology) domain [Function unknown];


Pssm-ID: 442654 [Multi-domain]  Cd Length: 410  Bit Score: 40.85  E-value: 9.01e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1150920481   1 MVYQTKRDVPVTLMIVFLILLIQADAIVPFVLGNMRVSG---WIIFILLTLLNGLIIWSFID---LKYVLKEHHLIIKAG 74
Cdd:COG3428     1 MSEPWRRLHPLSILVRLLKALALLLPVLLLLLAGVGAGGgllWVLLIALVLLLLLLLVSYLRwrtTRYRITDDRLIVRSG 80

                          90
                  ....*....|....
gi 1150920481  75 LI---KHQIPYENI 85
Cdd:COG3428    81 VLsrkRREIPLDRI 94
 
Name Accession Description Interval E-value
bPH_4 pfam06713
Bacterial PH domain; This family consists of several hypothetical proteins specific to ...
 61-136 7.10e-20

Bacterial PH domain; This family consists of several hypothetical proteins specific to Oceanobacillus and Bacillus species. Members of this family are typically around 130 residues in length. The function of this family is unknown. Members of this family have a PH domain like structure.


Pssm-ID: 369049  Cd Length: 74  Bit Score: 77.65  E-value: 7.10e-20
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1150920481  61 KYVLKEHHLIIKAGLIKHQIPYENIDKVVQKKKLWSgfRLIGSRHAITIYYqGGWGHAVISPQKSEEFIHKLKEKN 136
Cdd:pfam06713   2 KYILTEGTLIIKSGFFKKKIPIEDITKIRKTKSPLS--SPALSLDRLEIKY-GKYDTILISPKDKEEFIKLLKKRN 74
YdbT COG3428
Uncharacterized membrane protein YdbT, contains bPH2 (bacterial pleckstrin homology) domain ...
 1-85 9.01e-05

Uncharacterized membrane protein YdbT, contains bPH2 (bacterial pleckstrin homology) domain [Function unknown];


Pssm-ID: 442654 [Multi-domain]  Cd Length: 410  Bit Score: 40.85  E-value: 9.01e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1150920481   1 MVYQTKRDVPVTLMIVFLILLIQADAIVPFVLGNMRVSG---WIIFILLTLLNGLIIWSFID---LKYVLKEHHLIIKAG 74
Cdd:COG3428     1 MSEPWRRLHPLSILVRLLKALALLLPVLLLLLAGVGAGGgllWVLLIALVLLLLLLLVSYLRwrtTRYRITDDRLIVRSG 80

                          90
                  ....*....|....
gi 1150920481  75 LI---KHQIPYENI 85
Cdd:COG3428    81 VLsrkRREIPLDRI 94
bPH_5 pfam10882
Bacterial PH domain; This family of proteins with unknown function appear to be related to ...
 60-136 7.77e-03

Bacterial PH domain; This family of proteins with unknown function appear to be related to bacterial PH domains. This family was formerly known as DUF2679.


Pssm-ID: 378504  Cd Length: 100  Bit Score: 33.77  E-value: 7.77e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1150920481  60 LKYVLKEHHLIIKAGLIKHQIPYENIDKVVQKKKLWSGFRLIGSR-----------HAITIYY------------QGGWG 116
Cdd:pfam10882   1 LRYSLDDEGLVIRWIFGKVKIPLSDIEAVRVVEGVIKGVRLFGTGkpgyalgrfyiHDIGIAYmyatrlkrvlllKTKDK 80

                          90       100
                  ....*....|....*....|
gi 1150920481 117 HAVISPQKSEEFIHKLKEKN 136
Cdd:pfam10882  81 IYGISPENFEEFKEALESRL 100
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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