|
Name |
Accession |
Description |
Interval |
E-value |
| MGT |
TIGR01426 |
glycosyltransferase, MGT family; This model describes the MGT (macroside glycosyltransferase) ... |
8-408 |
0e+00 |
|
glycosyltransferase, MGT family; This model describes the MGT (macroside glycosyltransferase) subfamily of the UDP-glucuronosyltransferase family. Members include a number of glucosyl transferases for macrolide antibiotic inactivation, but also include transferases of glucose-related sugars for macrolide antibiotic production. [Cellular processes, Toxin production and resistance]
Pssm-ID: 273616 [Multi-domain] Cd Length: 392 Bit Score: 572.01 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 8 MSAPFWGHVFPSLAVAEELVHRGHHVTFVTGAEMADAVRSVGADFLRYESAFEGVDMYRLMTEAEPNAIPMTLYDEGMSM 87
Cdd:TIGR01426 1 FNIPAHGHVNPTLGVVEELVARGHRVTYATTEEFAERVEAAGAEFVLYGSALPPPDNPPENTEEEPIDIIEKLLDEAEDV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 88 LRSVEEHVGKDVPDLVAYDIATslNVGRVLAASWSRPAMTVIPLFASNGRFSTMQSVLDPDSAQVSAPPPRfseqmelfG 167
Cdd:TIGR01426 81 LPQLEEAYKGDRPDLIVYDIAS--WTGRLLARKWDVPVISSFPTFAANEEFEEMVSPAGEGSAEEGAIAER--------G 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 168 LGALVPRLAELLVSRGIT-EPVDDFLSGPEDFNLVCLPRAFQYAGDTFDERFAFVGPCLGKRRGLGEWTPPGSGHPVVLI 246
Cdd:TIGR01426 151 LAEYVARLSALLEEHGITtPPVEFLAAPRRDLNLVYTPKAFQPAGETFDDSFTFVGPCIGDRKEDGSWERPGDGRPVVLI 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 247 SLGTVFNRQLSFFRTFVRAFTDVPVHVVISLGKGVDPDVLRPLPPNVEVHRWVPHHAVLEHARALVTHGGTGSVMEALHA 326
Cdd:TIGR01426 231 SLGTVFNNQPSFYRTCVEAFRDLDWHVVLSVGRGVDPADLGELPPNVEVRQWVPQLEILKKADAFITHGGMNSTMEALFN 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 327 GCPVLVMPLSRDAQVTGRRIAELGLGRMVQPEEVTATTLRRHVLDIISDDAITRQVRQMQRATVEAGGALRAADETERFL 406
Cdd:TIGR01426 311 GVPMVAVPQGADQPMTARRIAELGLGRHLPPEEVTAEKLREAVLAVLSDPRYAERLRKMRAEIREAGGARRAADEIEGFL 390
|
..
gi 5921156 407 RR 408
Cdd:TIGR01426 391 AE 392
|
|
| YjiC |
COG1819 |
UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism]; |
4-388 |
2.61e-64 |
|
UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism];
Pssm-ID: 441424 [Multi-domain] Cd Length: 268 Bit Score: 207.02 E-value: 2.61e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 4 HFLFMSAPFWGHVFPSLAVAEELVHRGHHVTFVTGAEMADAVRSVGADFLRYEsafegvdmyrlmteaepnaipmtlyde 83
Cdd:COG1819 1 RILFVTLGGRGHVNPLLALARALRARGHEVTFATGPDFADLVEAAGLEFVDWR--------------------------- 53
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 84 gmsmlrsveehvgkdvPDLVAYDIATSlnVGRVLAASWSRPAMTVIPlfasngrfstmqsvldpdsaqvsappprfseqm 163
Cdd:COG1819 54 ----------------PDLVVSDPLAL--AAALAAEALGIPVVSLTP--------------------------------- 82
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 164 elfglgalvprlaellvsrgitepvddflsgpedfnlvclpRAFQYAGDTFDERFAFVGPCLGKRRG-LGEWTPPGSGHP 242
Cdd:COG1819 83 -----------------------------------------PELEYPRPPDPANVRFVGPLLPDGPAeLPPWLEEDAGRP 121
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 243 VVLISLGTVFNRQLSFFRTFVRAFTDVPVHVVISLGkGVDPDVLRPLPPNVEVHRWVPHHAVLEHARALVTHGGTGSVME 322
Cdd:COG1819 122 LVYVTLGTSANDRADLLRAVLEALADLGVRVVVTTG-GLDPAELGPLPDNVRVVDYVPQDALLPRADAVVHHGGAGTTAE 200
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 5921156 323 ALHAGCPVLVMPLSRDAQVTGRRIAELGLGRMVQPEEVTATTLRRHVLDIISDDAITRQVRQMQRA 388
Cdd:COG1819 201 ALRAGVPQVVVPFGGDQPLNAARVERLGAGLALPPRRLTAEALRAALRRLLADPSYRERAARLAAE 266
|
|
| GT1_Gtf-like |
cd03784 |
UDP-glycosyltransferases and similar proteins; This family includes the Gtfs, a group of ... |
4-399 |
2.98e-56 |
|
UDP-glycosyltransferases and similar proteins; This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics.
Pssm-ID: 340817 [Multi-domain] Cd Length: 404 Bit Score: 190.46 E-value: 2.98e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 4 HFLFMSAPFWGHVFPSLAVAEELVHRGHHVTFVTG-AEMADAVRSVGADFLRYESAFEGV--DMYRLMTEAEPNAIPMTL 80
Cdd:cd03784 2 RILFVPFPGQGHVNPMLPLAKALAARGHEVTVATPpFNFADLVEAAGLTFVPVGDDPDELelDSETNLGPDSLLELLRRL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 81 YDEGMSMLRSVEEHVGKD-VPDLVAYDIATSlnVGRVLAASWSRPAMTVIPLFASNGRFSTMQSVLDPDSAQVSAPPPRF 159
Cdd:cd03784 82 LKAADELLDDLLAALRSSwKPDLVIADPFAY--AGPLVAEELGIPSVRLFTGPATLLSAYLHPFGVLNLLLSSLLEPELF 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 160 seqmELFGLGALVPRLAELLVSRGITePVDDFLSGPEDFNLVCLPRAFQYAGDTFDERFAFVGPCLGKRR---GLGEWTP 236
Cdd:cd03784 160 ----LDPLLEVLDRLRERLGLPPFSL-VLLLLRLVPPLYVIGPTFPSLPPDRPRLPSVLGGLRIVPKNGPlpdELWEWLD 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 237 PGSGHPVVLISLGTVFNRQL-SFFRTFVRAFTDVPVHVVISLGKGvDPDVLRPLPPNVEVHRWVPHHAVLEHAR--ALVT 313
Cdd:cd03784 235 KQPPRSVVYVSFGSMVRDLPeELLELIAEALASLGQRFLWVVGPD-PLGGLERLPDNVLVVKWVPQDELLAHPAvgAFVT 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 314 HGGTGSVMEALHAGCPVLVMPLSRDAQVTGRRIAELGLGRMVQPEEVTATTLRRHVLDIISDDAITRQVRQMQRATVEAG 393
Cdd:cd03784 314 HGGWNSTLEALYAGVPMVVVPLFADQPNNAARVEELGAGVELDKDELTAEELAKAVREVLEDESYRRAAELLAELREEDG 393
|
....*.
gi 5921156 394 GALRAA 399
Cdd:cd03784 394 APSAAD 399
|
|
| egt |
PHA03392 |
ecdysteroid UDP-glucosyltransferase; Provisional |
243-411 |
1.38e-17 |
|
ecdysteroid UDP-glucosyltransferase; Provisional
Pssm-ID: 223071 [Multi-domain] Cd Length: 507 Bit Score: 84.62 E-value: 1.38e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 243 VVLISLGT---VFNRQLSFFRTFVRAFTDVPVHVvisLGKgVDPDVLRP-LPPNVEVHRWVPHHAVLEHA--RALVTHGG 316
Cdd:PHA03392 298 VVYVSFGSsidTNDMDNEFLQMLLRTFKKLPYNV---LWK-YDGEVEAInLPANVLTQKWFPQRAVLKHKnvKAFVTQGG 373
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 317 TGSVMEALHAGCPVLVMPLSRDAQVTGRRIAELGLGRMVQPEEVTATTLRRHVLDIISDDAITRQVRQMqRATVE--AGG 394
Cdd:PHA03392 374 VQSTDEAIDALVPMVGLPMMGDQFYNTNKYVELGIGRALDTVTVSAAQLVLAIVDVIENPKYRKNLKEL-RHLIRhqPMT 452
|
170
....*....|....*...
gi 5921156 395 ALRAA-DETERFLRRTRR 411
Cdd:PHA03392 453 PLHKAiWYTEHVIRNKHG 470
|
|
| UDPGT |
pfam00201 |
UDP-glucoronosyl and UDP-glucosyl transferase; |
241-375 |
3.56e-10 |
|
UDP-glucoronosyl and UDP-glucosyl transferase;
Pssm-ID: 278624 [Multi-domain] Cd Length: 499 Bit Score: 61.66 E-value: 3.56e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 241 HPVVLISLGT-VFNRQLSFFRTFVRAFTDVPVHVVISLgkgvdpDVLRP--LPPNVEVHRWVPHHAVLEH--ARALVTHG 315
Cdd:pfam00201 275 HGVVVFSLGSmVSNIPEEKANAIASALAQIPQKVLWRF------DGTKPstLGNNTRLVKWLPQNDLLGHpkTRAFITHA 348
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 316 GTGSVMEALHAGCPVLVMPLSRDAQVTGRRIAELGLGRMVQPEEVTATTLRRHVLDIISD 375
Cdd:pfam00201 349 GSNGVYEAICHGVPMVGMPLFGDQMDNAKHMEAKGAAVTLNVLTMTSEDLLNALKEVIND 408
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MGT |
TIGR01426 |
glycosyltransferase, MGT family; This model describes the MGT (macroside glycosyltransferase) ... |
8-408 |
0e+00 |
|
glycosyltransferase, MGT family; This model describes the MGT (macroside glycosyltransferase) subfamily of the UDP-glucuronosyltransferase family. Members include a number of glucosyl transferases for macrolide antibiotic inactivation, but also include transferases of glucose-related sugars for macrolide antibiotic production. [Cellular processes, Toxin production and resistance]
Pssm-ID: 273616 [Multi-domain] Cd Length: 392 Bit Score: 572.01 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 8 MSAPFWGHVFPSLAVAEELVHRGHHVTFVTGAEMADAVRSVGADFLRYESAFEGVDMYRLMTEAEPNAIPMTLYDEGMSM 87
Cdd:TIGR01426 1 FNIPAHGHVNPTLGVVEELVARGHRVTYATTEEFAERVEAAGAEFVLYGSALPPPDNPPENTEEEPIDIIEKLLDEAEDV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 88 LRSVEEHVGKDVPDLVAYDIATslNVGRVLAASWSRPAMTVIPLFASNGRFSTMQSVLDPDSAQVSAPPPRfseqmelfG 167
Cdd:TIGR01426 81 LPQLEEAYKGDRPDLIVYDIAS--WTGRLLARKWDVPVISSFPTFAANEEFEEMVSPAGEGSAEEGAIAER--------G 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 168 LGALVPRLAELLVSRGIT-EPVDDFLSGPEDFNLVCLPRAFQYAGDTFDERFAFVGPCLGKRRGLGEWTPPGSGHPVVLI 246
Cdd:TIGR01426 151 LAEYVARLSALLEEHGITtPPVEFLAAPRRDLNLVYTPKAFQPAGETFDDSFTFVGPCIGDRKEDGSWERPGDGRPVVLI 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 247 SLGTVFNRQLSFFRTFVRAFTDVPVHVVISLGKGVDPDVLRPLPPNVEVHRWVPHHAVLEHARALVTHGGTGSVMEALHA 326
Cdd:TIGR01426 231 SLGTVFNNQPSFYRTCVEAFRDLDWHVVLSVGRGVDPADLGELPPNVEVRQWVPQLEILKKADAFITHGGMNSTMEALFN 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 327 GCPVLVMPLSRDAQVTGRRIAELGLGRMVQPEEVTATTLRRHVLDIISDDAITRQVRQMQRATVEAGGALRAADETERFL 406
Cdd:TIGR01426 311 GVPMVAVPQGADQPMTARRIAELGLGRHLPPEEVTAEKLREAVLAVLSDPRYAERLRKMRAEIREAGGARRAADEIEGFL 390
|
..
gi 5921156 407 RR 408
Cdd:TIGR01426 391 AE 392
|
|
| YjiC |
COG1819 |
UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism]; |
4-388 |
2.61e-64 |
|
UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism];
Pssm-ID: 441424 [Multi-domain] Cd Length: 268 Bit Score: 207.02 E-value: 2.61e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 4 HFLFMSAPFWGHVFPSLAVAEELVHRGHHVTFVTGAEMADAVRSVGADFLRYEsafegvdmyrlmteaepnaipmtlyde 83
Cdd:COG1819 1 RILFVTLGGRGHVNPLLALARALRARGHEVTFATGPDFADLVEAAGLEFVDWR--------------------------- 53
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 84 gmsmlrsveehvgkdvPDLVAYDIATSlnVGRVLAASWSRPAMTVIPlfasngrfstmqsvldpdsaqvsappprfseqm 163
Cdd:COG1819 54 ----------------PDLVVSDPLAL--AAALAAEALGIPVVSLTP--------------------------------- 82
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 164 elfglgalvprlaellvsrgitepvddflsgpedfnlvclpRAFQYAGDTFDERFAFVGPCLGKRRG-LGEWTPPGSGHP 242
Cdd:COG1819 83 -----------------------------------------PELEYPRPPDPANVRFVGPLLPDGPAeLPPWLEEDAGRP 121
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 243 VVLISLGTVFNRQLSFFRTFVRAFTDVPVHVVISLGkGVDPDVLRPLPPNVEVHRWVPHHAVLEHARALVTHGGTGSVME 322
Cdd:COG1819 122 LVYVTLGTSANDRADLLRAVLEALADLGVRVVVTTG-GLDPAELGPLPDNVRVVDYVPQDALLPRADAVVHHGGAGTTAE 200
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 5921156 323 ALHAGCPVLVMPLSRDAQVTGRRIAELGLGRMVQPEEVTATTLRRHVLDIISDDAITRQVRQMQRA 388
Cdd:COG1819 201 ALRAGVPQVVVPFGGDQPLNAARVERLGAGLALPPRRLTAEALRAALRRLLADPSYRERAARLAAE 266
|
|
| GT1_Gtf-like |
cd03784 |
UDP-glycosyltransferases and similar proteins; This family includes the Gtfs, a group of ... |
4-399 |
2.98e-56 |
|
UDP-glycosyltransferases and similar proteins; This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics.
Pssm-ID: 340817 [Multi-domain] Cd Length: 404 Bit Score: 190.46 E-value: 2.98e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 4 HFLFMSAPFWGHVFPSLAVAEELVHRGHHVTFVTG-AEMADAVRSVGADFLRYESAFEGV--DMYRLMTEAEPNAIPMTL 80
Cdd:cd03784 2 RILFVPFPGQGHVNPMLPLAKALAARGHEVTVATPpFNFADLVEAAGLTFVPVGDDPDELelDSETNLGPDSLLELLRRL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 81 YDEGMSMLRSVEEHVGKD-VPDLVAYDIATSlnVGRVLAASWSRPAMTVIPLFASNGRFSTMQSVLDPDSAQVSAPPPRF 159
Cdd:cd03784 82 LKAADELLDDLLAALRSSwKPDLVIADPFAY--AGPLVAEELGIPSVRLFTGPATLLSAYLHPFGVLNLLLSSLLEPELF 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 160 seqmELFGLGALVPRLAELLVSRGITePVDDFLSGPEDFNLVCLPRAFQYAGDTFDERFAFVGPCLGKRR---GLGEWTP 236
Cdd:cd03784 160 ----LDPLLEVLDRLRERLGLPPFSL-VLLLLRLVPPLYVIGPTFPSLPPDRPRLPSVLGGLRIVPKNGPlpdELWEWLD 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 237 PGSGHPVVLISLGTVFNRQL-SFFRTFVRAFTDVPVHVVISLGKGvDPDVLRPLPPNVEVHRWVPHHAVLEHAR--ALVT 313
Cdd:cd03784 235 KQPPRSVVYVSFGSMVRDLPeELLELIAEALASLGQRFLWVVGPD-PLGGLERLPDNVLVVKWVPQDELLAHPAvgAFVT 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 314 HGGTGSVMEALHAGCPVLVMPLSRDAQVTGRRIAELGLGRMVQPEEVTATTLRRHVLDIISDDAITRQVRQMQRATVEAG 393
Cdd:cd03784 314 HGGWNSTLEALYAGVPMVVVPLFADQPNNAARVEELGAGVELDKDELTAEELAKAVREVLEDESYRRAAELLAELREEDG 393
|
....*.
gi 5921156 394 GALRAA 399
Cdd:cd03784 394 APSAAD 399
|
|
| egt |
PHA03392 |
ecdysteroid UDP-glucosyltransferase; Provisional |
243-411 |
1.38e-17 |
|
ecdysteroid UDP-glucosyltransferase; Provisional
Pssm-ID: 223071 [Multi-domain] Cd Length: 507 Bit Score: 84.62 E-value: 1.38e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 243 VVLISLGT---VFNRQLSFFRTFVRAFTDVPVHVvisLGKgVDPDVLRP-LPPNVEVHRWVPHHAVLEHA--RALVTHGG 316
Cdd:PHA03392 298 VVYVSFGSsidTNDMDNEFLQMLLRTFKKLPYNV---LWK-YDGEVEAInLPANVLTQKWFPQRAVLKHKnvKAFVTQGG 373
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 317 TGSVMEALHAGCPVLVMPLSRDAQVTGRRIAELGLGRMVQPEEVTATTLRRHVLDIISDDAITRQVRQMqRATVE--AGG 394
Cdd:PHA03392 374 VQSTDEAIDALVPMVGLPMMGDQFYNTNKYVELGIGRALDTVTVSAAQLVLAIVDVIENPKYRKNLKEL-RHLIRhqPMT 452
|
170
....*....|....*...
gi 5921156 395 ALRAA-DETERFLRRTRR 411
Cdd:PHA03392 453 PLHKAiWYTEHVIRNKHG 470
|
|
| UDPGT |
pfam00201 |
UDP-glucoronosyl and UDP-glucosyl transferase; |
241-375 |
3.56e-10 |
|
UDP-glucoronosyl and UDP-glucosyl transferase;
Pssm-ID: 278624 [Multi-domain] Cd Length: 499 Bit Score: 61.66 E-value: 3.56e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 241 HPVVLISLGT-VFNRQLSFFRTFVRAFTDVPVHVVISLgkgvdpDVLRP--LPPNVEVHRWVPHHAVLEH--ARALVTHG 315
Cdd:pfam00201 275 HGVVVFSLGSmVSNIPEEKANAIASALAQIPQKVLWRF------DGTKPstLGNNTRLVKWLPQNDLLGHpkTRAFITHA 348
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 316 GTGSVMEALHAGCPVLVMPLSRDAQVTGRRIAELGLGRMVQPEEVTATTLRRHVLDIISD 375
Cdd:pfam00201 349 GSNGVYEAICHGVPMVGMPLFGDQMDNAKHMEAKGAAVTLNVLTMTSEDLLNALKEVIND 408
|
|
| GT28_MurG |
cd03785 |
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; MurG (EC 2.4. ... |
14-388 |
2.05e-09 |
|
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
Pssm-ID: 340818 [Multi-domain] Cd Length: 350 Bit Score: 58.77 E-value: 2.05e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 14 GHVFPSLAVAEELVHRGHHVTFVTGAemadavRSVGADFL-RYESAFEGVDMYRLmteaePNAIPMTLYDEGMSMLRSVE 92
Cdd:cd03785 11 GHIFPALALAEELRKRGAEILFIGTK------RGLEAKLVpEAGIPFHTIPISGL-----RRKGSLKNLKAPFKLLKGLR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 93 E---HVGKDVPDLVaydIAT----SLNVgrVLAASWSRpamtvIPLFasngrfstmqsVLDPDSaqvsappprfseqmel 165
Cdd:cd03785 80 QarkILRKFKPDVV---IGFggyvSGPV--VLAARLLG-----IPLI-----------IHEQNA---------------- 122
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 166 fglgalVPRLAELLVSRgitePVDD-FLSGPEDFNLVCLPRAFqyagdtfderfaFVG----PCLGKRRGLGEWTPPGSG 240
Cdd:cd03785 123 ------VPGLANRLLSR----FADKvAVSFPETKKYFPAAKVV------------VTGnpvrEEILNLRKELKRFGLPPD 180
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 241 HPVVLI---SLG-TVFNRQLsffRTFVRAFTDVPVHVVISLGKGvDPDVLR----PLPPNVEVhrwVPH----HAVLEHA 308
Cdd:cd03785 181 KPTLLVfggSQGaRAINRAV---PKALPKLLERGIQVIHQTGKG-DYDEVKklyeDLGINVKV---FPFiddmAAAYAAA 253
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 309 RALVTHGGTGSVMEALHAGCPVLVMPL---SRDAQ-VTGRRIAELGLGRMVQPEEVTATTLRRHVLDIISDDAITRQVRQ 384
Cdd:cd03785 254 DLVISRAGASTIAELTAAGKPAILIPYpyaADDHQeANARALEKAGAAIVIDQEELTPEVLAEAILDLLNDPERLKKMAE 333
|
....
gi 5921156 385 MQRA 388
Cdd:cd03785 334 AAKK 337
|
|
| COG4671 |
COG4671 |
Predicted glycosyl transferase [General function prediction only]; |
291-412 |
1.04e-06 |
|
Predicted glycosyl transferase [General function prediction only];
Pssm-ID: 443708 [Multi-domain] Cd Length: 391 Bit Score: 50.24 E-value: 1.04e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 291 PNVEVHRWVPH-HAVLEHARALVTHGGTGSVMEALHAGCPVLVMPlsRDAQVT-----GRRIAELGLGRMVQPEEVTATT 364
Cdd:COG4671 274 PNVTVERFTPDfEALLAAADLSVSMGGYNTVCEILSTGKPALIVP--RTAPRTeqlirAERLAELGLVDVLHPEDLTPEA 351
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 5921156 365 LRRHVLDIISDDAitrqvrqmQRATVEAGGALRAADETERFLRRTRRH 412
Cdd:COG4671 352 LARAIAAALARPP--------RRSPLDLDGLARTARILAELLGARSAA 391
|
|
| MurG |
COG0707 |
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope ... |
226-408 |
7.02e-06 |
|
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440471 [Multi-domain] Cd Length: 363 Bit Score: 47.82 E-value: 7.02e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 226 GKRRGLGEWTPPGSGHPVVLI---SLGTVfnrqlSFFRTFVRAFTDVP---VHVVISLGKGvDPDVLR-----PLPPNVE 294
Cdd:COG0707 171 LDRPEARAKLGLDPDKPTLLVfggSQGAR-----ALNEAVPAALAALLearLQVVHQTGKG-DYEEVRaayaaAIRPNAE 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 295 VHRWVPH-HAVLEHARALVTHGGTGSVMEALHAGCPVLVMPL---SRDAQVT-GRRIAELGLGRMVQPEEVTATTLRRHV 369
Cdd:COG0707 245 VFPFIDDmADAYAAADLVISRAGASTVAELAALGKPAILVPLphaADDHQTKnARALVEAGAAVLIPQSELTPEKLAEAL 324
|
170 180 190
....*....|....*....|....*....|....*....
gi 5921156 370 LDIISDDAITRQVRQMQRATVEAGGALRAADETERFLRR 408
Cdd:COG0707 325 EELLEDPERLAKMAEAARALARPDAAERIADLILELAKG 363
|
|
| PLN02992 |
PLN02992 |
coniferyl-alcohol glucosyltransferase |
295-410 |
2.98e-05 |
|
coniferyl-alcohol glucosyltransferase
Pssm-ID: 178572 [Multi-domain] Cd Length: 481 Bit Score: 46.13 E-value: 2.98e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 295 VHRWVPHHAVLEHAR--ALVTHGGTGSVMEALHAGCPVLVMPLSRDAQVTGRRIA-ELGLG-RMVQPEEVTATT----LR 366
Cdd:PLN02992 342 VPSWAPQAEILAHQAvgGFLTHCGWSSTLESVVGGVPMIAWPLFAEQNMNAALLSdELGIAvRSDDPKEVISRSkieaLV 421
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 5921156 367 RHVLDIISDDAITRQVRQMQRA-----TVEAGGAL-----RAADETERFLRRTR 410
Cdd:PLN02992 422 RKVMVEEEGEEMRRKVKKLRDTaemslSIDGGGVAheslcRVTKECQRFLERVR 475
|
|
| PLN02555 |
PLN02555 |
limonoid glucosyltransferase |
4-342 |
6.68e-05 |
|
limonoid glucosyltransferase
Pssm-ID: 178170 [Multi-domain] Cd Length: 480 Bit Score: 44.79 E-value: 6.68e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 4 HFLFMSAPFWGHVFPSLAVAEELVHRGHHVTFVT----GAEMADA-------VRSVGADFLRYESAFEGVDmyrlmtEAE 72
Cdd:PLN02555 9 HVMLVSFPGQGHVNPLLRLGKLLASKGLLVTFVTteswGKKMRQAnkiqdgvLKPVGDGFIRFEFFEDGWA------EDD 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 73 PNAIPMTLYdegmsmlRSVEEHVGK-DVPDLV---------------------AYDIATSLNV----------------- 113
Cdd:PLN02555 83 PRRQDLDLY-------LPQLELVGKrEIPNLVkryaeqgrpvsclinnpfipwVCDVAEELGIpsavlwvqscacfsayy 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 114 ----GRVLAASWSRPAMTV----IPLFasngRFSTMQSVLDPDS----------AQVSAPPPRFSEQMELFGlgALVPRL 175
Cdd:PLN02555 156 hyyhGLVPFPTETEPEIDVqlpcMPLL----KYDEIPSFLHPSSpypflrrailGQYKNLDKPFCILIDTFQ--ELEKEI 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 176 AELLVSRGITEPVddflsGPedfnLVCLPRAFQYA--GDTFDErfafVGPCLgkrrglgEW---TPPGSghpVVLISLGT 250
Cdd:PLN02555 230 IDYMSKLCPIKPV-----GP----LFKMAKTPNSDvkGDISKP----ADDCI-------EWldsKPPSS---VVYISFGT 286
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 251 V---------------FNRQLSFFRTfVRaftdvPVHvvisLGKGVDPDVL-----RPLPPNVEVHRWVPHHAVLEHAR- 309
Cdd:PLN02555 287 VvylkqeqideiaygvLNSGVSFLWV-MR-----PPH----KDSGVEPHVLpeeflEKAGDKGKIVQWCPQEKVLAHPSv 356
|
410 420 430
....*....|....*....|....*....|....
gi 5921156 310 -ALVTHGGTGSVMEALHAGCPVLVMPLSRDaQVT 342
Cdd:PLN02555 357 aCFVTHCGWNSTMEALSSGVPVVCFPQWGD-QVT 389
|
|
| Glyco_tran_28_C |
pfam04101 |
Glycosyltransferase family 28 C-terminal domain; The glycosyltransferase family 28 includes ... |
259-375 |
9.54e-05 |
|
Glycosyltransferase family 28 C-terminal domain; The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). Structural analysis suggests the C-terminal domain contains the UDP-GlcNAc binding site.
Pssm-ID: 427711 [Multi-domain] Cd Length: 166 Bit Score: 42.70 E-value: 9.54e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 259 FRTFVRAFTDV--------PVHVVISLGKGVDPDVLRPLP---PNVEVHRWVPHHAVLEHARALV-THGGTGSVMEALHA 326
Cdd:pfam04101 11 ARALNELVLSVlpllelkgELQVLHQTGKGDLEEVKIDYAelgINYEVFPFIDNMAEYIKAADLViSRAGAGTIAELLAL 90
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 5921156 327 GCPVLVMPL---SRDAQ-VTGRRIAELGLGRMVQPEEVTATTLRRHVLDIISD 375
Cdd:pfam04101 91 GKPAILVPNpsaARGHQdNNAKELVKAGAALVILQKELTPEKLIEALLKLLLN 143
|
|
| PLN02210 |
PLN02210 |
UDP-glucosyl transferase |
233-354 |
1.61e-04 |
|
UDP-glucosyl transferase
Pssm-ID: 215127 [Multi-domain] Cd Length: 456 Bit Score: 43.87 E-value: 1.61e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 233 EWTPPGSGHPVVLISLGTVFNRQLSFFRTFVRAFTD--VPVHVVISLG-KGVDPDVLRPLPPNVE--VHRWVPHHAVLEH 307
Cdd:PLN02210 261 EWLDKQARSSVVYISFGSMLESLENQVETIAKALKNrgVPFLWVIRPKeKAQNVQVLQEMVKEGQgvVLEWSPQEKILSH 340
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 5921156 308 A--RALVTHGGTGSVMEALHAGCPVLVMPLSRDAQVTGRRIAEL-GLG-RM 354
Cdd:PLN02210 341 MaiSCFVTHCGWNSTIETVVAGVPVVAYPSWTDQPIDARLLVDVfGIGvRM 391
|
|
| murG |
PRK00726 |
undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional |
14-37 |
3.81e-04 |
|
undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional
Pssm-ID: 234825 [Multi-domain] Cd Length: 357 Bit Score: 42.43 E-value: 3.81e-04
10 20
....*....|....*....|....
gi 5921156 14 GHVFPSLAVAEELVHRGHHVTFVT 37
Cdd:PRK00726 13 GHVFPALALAEELKKRGWEVLYLG 36
|
|
| Glyco_transf_28 |
pfam03033 |
Glycosyltransferase family 28 N-terminal domain; The glycosyltransferase family 28 includes ... |
14-63 |
4.45e-04 |
|
Glycosyltransferase family 28 N-terminal domain; The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). This N-terminal domain contains the acceptor binding site and likely membrane association site. This family also contains a large number of proteins that probably have quite distinct activities.
Pssm-ID: 427107 [Multi-domain] Cd Length: 139 Bit Score: 40.35 E-value: 4.45e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 5921156 14 GHVFPSLAVAEELVHRGHHVTF-VTGAEMADAVrsvgadFLRYESAFEGVD 63
Cdd:pfam03033 10 GHVFPALALAKELKKRGHEVRVlGTKRGFEEFL------VEKAGIEFEPIP 54
|
|
| RfaB |
COG0438 |
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ... |
302-411 |
2.47e-03 |
|
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440207 [Multi-domain] Cd Length: 123 Bit Score: 37.66 E-value: 2.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 302 HAVLEHARALV---THGGTG-SVMEALHAGCPVLVMPLSRDAQVtgrrIAELGLGRMVQPEEVTAttLRRHVLDIISDDA 377
Cdd:COG0438 15 EALLAAADVFVlpsRSEGFGlVLLEAMAAGLPVIATDVGGLPEV----IEDGETGLLVPPGDPEA--LAEAILRLLEDPE 88
|
90 100 110
....*....|....*....|....*....|....*
gi 5921156 378 ITRQVRQMQRATVEAGGALRA-ADETERFLRRTRR 411
Cdd:COG0438 89 LRRRLGEAARERAEERFSWEAiAERLLALYEELLA 123
|
|
| PLN02167 |
PLN02167 |
UDP-glycosyltransferase family protein |
298-407 |
2.99e-03 |
|
UDP-glycosyltransferase family protein
Pssm-ID: 215112 [Multi-domain] Cd Length: 475 Bit Score: 39.78 E-value: 2.99e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 298 WVPHHAVLEHARA--LVTHGGTGSVMEALHAGCPVLVMPLSRDAQVTGRRIA-ELGL------------GRMVQPEEVTA 362
Cdd:PLN02167 347 WAPQVEILAHKAIggFVSHCGWNSVLESLWFGVPIATWPMYAEQQLNAFTMVkELGLavelrldyvsayGEIVKADEIAG 426
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 5921156 363 TTlrRHVLDiiSDDAITRQVRQMQRATVEA---GGALRAAdeTERFLR 407
Cdd:PLN02167 427 AV--RSLMD--GEDVPRKKVKEIAEAARKAvmdGGSSFVA--VKRFID 468
|
|
| PLN03004 |
PLN03004 |
UDP-glycosyltransferase |
295-388 |
3.26e-03 |
|
UDP-glycosyltransferase
Pssm-ID: 178581 Cd Length: 451 Bit Score: 39.67 E-value: 3.26e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 295 VHRWVPHHAVLEHAR--ALVTHGGTGSVMEALHAGCPVLVMPLSRDAQVTGRRIA-ELGLGRMVQPEE---VTATTLRRH 368
Cdd:PLN03004 338 VKSWAPQVPVLNHKAvgGFVTHCGWNSILEAVCAGVPMVAWPLYAEQRFNRVMIVdEIKIAISMNESEtgfVSSTEVEKR 417
|
90 100
....*....|....*....|
gi 5921156 369 VLDIISDDAITRQVRQMQRA 388
Cdd:PLN03004 418 VQEIIGECPVRERTMAMKNA 437
|
|
| GT4_PimA-like |
cd03801 |
phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 ... |
236-407 |
3.85e-03 |
|
phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.
Pssm-ID: 340831 [Multi-domain] Cd Length: 366 Bit Score: 39.06 E-value: 3.85e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 236 PPGSGHPVVLISLGTVFNR--QLsffrTFVRAFTDVP-----VHVVISLGKGVDPDVLR----PLPPNVEVHRWVPHH-- 302
Cdd:cd03801 186 LGIPPDRPVLLFVGRLSPRkgVD----LLLEALAKLLrrgpdVRLVIVGGDGPLRAELEelelGLGDRVRFLGFVPDEel 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5921156 303 -AVLEHARALV---THGGTG-SVMEALHAGCPVLVmplSRdaqVTG-RRIAELGLGRMVQPEEVTAtTLRRHVLDIISDD 376
Cdd:cd03801 262 pALYAAADVFVlpsRYEGFGlVVLEAMAAGLPVVA---TD---VGGlPEVVEDGEGGLVVPPDDVE-ALADALLRLLADP 334
|
170 180 190
....*....|....*....|....*....|..
gi 5921156 377 AITRQVRQMQRATVEAGGAL-RAADETERFLR 407
Cdd:cd03801 335 ELRARLGRAARERVAERFSWeRVAERLLDLYR 366
|
|
| |
