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Conserved domains on  [gi|10434114|dbj|BAB14135|]
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unnamed protein product [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Ndc1_Nup super family cl12364
Nucleoporin protein Ndc1-Nup; Ndc1 is a nucleoporin protein that is a component of the Nuclear ...
 1-128 5.18e-40

Nucleoporin protein Ndc1-Nup; Ndc1 is a nucleoporin protein that is a component of the Nuclear Pore Complex, and, in fungi, also of the Spindle Pole Body. It consists of six transmembrane segments, three lumenal loops, both concentrated at the N-terminus and cytoplasmic domains largely at the C-terminus, all of which are well conserved.


The actual alignment was detected with superfamily member pfam09531:

Pssm-ID: 462824  Cd Length: 522  Bit Score: 139.77  E-value: 5.18e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10434114     1 MYFFSKHPEASIQAVFSDAQMHIWALEGLSHLVAASFTEDRFGVVQTTLPAILNTLLTLQEAVDKY---FKLPHASSKPP 77
Cdd:pfam09531 392 GYLFRQTLRRRLEALVANPQLIINAIEALSNLLVASLTEDQYGVVQRDVPEILRTLTRLIEALDKFkdqLPAHWTDVEGP 471

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 10434114    78 RISGSLVDTSYKTLRFAFRASLKTAIYRITTTFGEHLNAVQASAEHQKRLQ 128
Cdd:pfam09531 472 AQSSAREVPSLLDEVDALLDALKTGLYRIVTAFGPYLNDLGLSPEDLRLAK 522
 
Name Accession Description Interval E-value
Ndc1_Nup pfam09531
Nucleoporin protein Ndc1-Nup; Ndc1 is a nucleoporin protein that is a component of the Nuclear ...
 1-128 5.18e-40

Nucleoporin protein Ndc1-Nup; Ndc1 is a nucleoporin protein that is a component of the Nuclear Pore Complex, and, in fungi, also of the Spindle Pole Body. It consists of six transmembrane segments, three lumenal loops, both concentrated at the N-terminus and cytoplasmic domains largely at the C-terminus, all of which are well conserved.


Pssm-ID: 462824  Cd Length: 522  Bit Score: 139.77  E-value: 5.18e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10434114     1 MYFFSKHPEASIQAVFSDAQMHIWALEGLSHLVAASFTEDRFGVVQTTLPAILNTLLTLQEAVDKY---FKLPHASSKPP 77
Cdd:pfam09531 392 GYLFRQTLRRRLEALVANPQLIINAIEALSNLLVASLTEDQYGVVQRDVPEILRTLTRLIEALDKFkdqLPAHWTDVEGP 471

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 10434114    78 RISGSLVDTSYKTLRFAFRASLKTAIYRITTTFGEHLNAVQASAEHQKRLQ 128
Cdd:pfam09531 472 AQSSAREVPSLLDEVDALLDALKTGLYRIVTAFGPYLNDLGLSPEDLRLAK 522
 
Name Accession Description Interval E-value
Ndc1_Nup pfam09531
Nucleoporin protein Ndc1-Nup; Ndc1 is a nucleoporin protein that is a component of the Nuclear ...
 1-128 5.18e-40

Nucleoporin protein Ndc1-Nup; Ndc1 is a nucleoporin protein that is a component of the Nuclear Pore Complex, and, in fungi, also of the Spindle Pole Body. It consists of six transmembrane segments, three lumenal loops, both concentrated at the N-terminus and cytoplasmic domains largely at the C-terminus, all of which are well conserved.


Pssm-ID: 462824  Cd Length: 522  Bit Score: 139.77  E-value: 5.18e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10434114     1 MYFFSKHPEASIQAVFSDAQMHIWALEGLSHLVAASFTEDRFGVVQTTLPAILNTLLTLQEAVDKY---FKLPHASSKPP 77
Cdd:pfam09531 392 GYLFRQTLRRRLEALVANPQLIINAIEALSNLLVASLTEDQYGVVQRDVPEILRTLTRLIEALDKFkdqLPAHWTDVEGP 471

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 10434114    78 RISGSLVDTSYKTLRFAFRASLKTAIYRITTTFGEHLNAVQASAEHQKRLQ 128
Cdd:pfam09531 472 AQSSAREVPSLLDEVDALLDALKTGLYRIVTAFGPYLNDLGLSPEDLRLAK 522
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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