NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|12862000|dbj|BAB32324|]
View 

unnamed protein product, partial [Mus musculus]

Protein Classification

PRELI/slowmo family protein( domain architecture ID 10520218)

PRELI/slowmo family protein may regulate lipid accumulation in mitochondria by shuttling phospholipids in a lipid-specific manner across the intermembrane space

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
PRELI pfam04707
PRELI-like family; This family includes a conserved region found in the PRELI protein and ...
 16-173 2.78e-58

PRELI-like family; This family includes a conserved region found in the PRELI protein and yeast YLR168C gene MSF1 product. The function of this protein is unknown, though it is thought to be involved in intra-mitochondrial protein sorting. This region is also found in a number of other eukaryotic proteins.


:

Pssm-ID: 398400  Cd Length: 156  Bit Score: 179.41  E-value: 2.78e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12862000    16 EQVVACFLRKYPNPMDKNVISVKTVEEKKDEsTGLIYRKRIAICQNVVPEILRKVsILKVPDIQLEEESWLSLQKRNMAI 95
Cdd:pfam04707   1 EQVTAAFWRRYPNPYSPHVISVDVLERELDD-DGKLHTERLLTKQGRLPRWLKKL-IGVAHTVYVVEVSVVDPKKRTLTL 78

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 12862000    96 RSHCLTWTQYASMREESVFRESVENPNWTEFIQTGRISITG-AGFLNCILETFASTFLRQgAQKGIRIMEMLLKEQCGS 173
Cdd:pfam04707  79 ETRNLTFSNRLSVDERCRYTPHPENPNWTIFDQEASISISGfFGFSSKVEKWSLKRFSQN-AKKGREGMEYVLQKLEEE 156
 
Name Accession Description Interval E-value
PRELI pfam04707
PRELI-like family; This family includes a conserved region found in the PRELI protein and ...
 16-173 2.78e-58

PRELI-like family; This family includes a conserved region found in the PRELI protein and yeast YLR168C gene MSF1 product. The function of this protein is unknown, though it is thought to be involved in intra-mitochondrial protein sorting. This region is also found in a number of other eukaryotic proteins.


Pssm-ID: 398400  Cd Length: 156  Bit Score: 179.41  E-value: 2.78e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12862000    16 EQVVACFLRKYPNPMDKNVISVKTVEEKKDEsTGLIYRKRIAICQNVVPEILRKVsILKVPDIQLEEESWLSLQKRNMAI 95
Cdd:pfam04707   1 EQVTAAFWRRYPNPYSPHVISVDVLERELDD-DGKLHTERLLTKQGRLPRWLKKL-IGVAHTVYVVEVSVVDPKKRTLTL 78

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 12862000    96 RSHCLTWTQYASMREESVFRESVENPNWTEFIQTGRISITG-AGFLNCILETFASTFLRQgAQKGIRIMEMLLKEQCGS 173
Cdd:pfam04707  79 ETRNLTFSNRLSVDERCRYTPHPENPNWTIFDQEASISISGfFGFSSKVEKWSLKRFSQN-AKKGREGMEYVLQKLEEE 156
 
Name Accession Description Interval E-value
PRELI pfam04707
PRELI-like family; This family includes a conserved region found in the PRELI protein and ...
 16-173 2.78e-58

PRELI-like family; This family includes a conserved region found in the PRELI protein and yeast YLR168C gene MSF1 product. The function of this protein is unknown, though it is thought to be involved in intra-mitochondrial protein sorting. This region is also found in a number of other eukaryotic proteins.


Pssm-ID: 398400  Cd Length: 156  Bit Score: 179.41  E-value: 2.78e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12862000    16 EQVVACFLRKYPNPMDKNVISVKTVEEKKDEsTGLIYRKRIAICQNVVPEILRKVsILKVPDIQLEEESWLSLQKRNMAI 95
Cdd:pfam04707   1 EQVTAAFWRRYPNPYSPHVISVDVLERELDD-DGKLHTERLLTKQGRLPRWLKKL-IGVAHTVYVVEVSVVDPKKRTLTL 78

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 12862000    96 RSHCLTWTQYASMREESVFRESVENPNWTEFIQTGRISITG-AGFLNCILETFASTFLRQgAQKGIRIMEMLLKEQCGS 173
Cdd:pfam04707  79 ETRNLTFSNRLSVDERCRYTPHPENPNWTIFDQEASISISGfFGFSSKVEKWSLKRFSQN-AKKGREGMEYVLQKLEEE 156
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH