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unnamed protein product [Homo sapiens]
Protein Classification
List of domain hits
Name
Accession
Description
Interval
E-value
Smc super family
cl34174 Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
221-687
1.09e-11
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
COG1196 :Pssm-ID: 440809 [Multi-domain]
Cd Length: 983
Bit Score: 68.42
E-value: 1.09e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 221 IEQ L RKK L RQAKL EL RVAV A KV EEL TNVTED L QGQMKKKEKDVVSAHGRE E ASDRRLQQ L QSSIKQ LE IRLCVTIQEANQ 300
Cdd:COG1196 234 LRE L EAE L EELEA EL EELE A EL EEL EAELAE L EAELEELRLELEELELEL E EAQAEEYE L LAELAR LE QDIARLEERRRE 313
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 301 L RTENTH LE KQTR EL QAKCN ELE N E RY E AIVRARNSMQL LEEA NLQKSQ A LLEEKQK E EDIEKMK E TVSRFVQD -- ATI R 378
Cdd:COG1196 314 L EERLEE LE EELA EL EEELE ELE E E LE E LEEELEEAEEE LEEA EAELAE A EEALLEA E AELAEAE E ELEELAEE ll EAL R 393
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 379 TKK E V A NTKKQCNIQISR L T E E L SA L QM E CA E KQGQIERVIK E KKAV EE E LE KIYR E GRGN E CDYRK L E E MHQRF L VSER 458
Cdd:COG1196 394 AAA E L A AQLEELEEAEEA L L E R L ER L EE E LE E LEEALAELEE E EEEE EE A LE EAAE E EAEL E EEEEA L L E LLAEL L EEAA 473
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 459 SKDDLQLR L TRAENRIKQLETDSS E EISR Y QEMIQ -- K LQNV L ESE R ENC G L V SE ------------------------- 511
Cdd:COG1196 474 LLEAALAE L LEELAEAAARLLLLL E AEAD Y EGFLE gv K AALL L AGL R GLA G A V AV ligveaayeaaleaalaaalqnivv 553
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 512 ------- QRLKLQQEN K QL R KETES L R KI ALE A QKK A KVKISTMEHEFSIKE --- R GFEVQLREME D SNRNSIVELRH L L 581
Cdd:COG1196 554 eddevaa AAIEYLKAA K AG R ATFLP L D KI RAR A ALA A ALARGAIGAAVDLVA sdl R EADARYYVLG D TLLGRTLVAAR L E 633
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 582 A TQQK A ANRWKEETKKLT E SAEIRINNLKSEL SR QK L HTQE L LSQL E MANEKVAEN E KLILEHQEKANRLQRRLSQ AE ER 661
Cdd:COG1196 634 A ALRR A VTLAGRLREVTL E GEGGSAGGSLTGG SR RE L LAAL L EAEA E LEELAERLA E EELELEEALLAEEEEEREL AE AE 713
490 500
....*....|....*....|....*.
gi 16549896 662 AASASQQ L SVITVQRRKA A SLMN L EN 687
Cdd:COG1196 714 EERLEEE L EEEALEEQLE A EREE L LE 739
SMC_N super family
cl47134 RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
69-370
1.72e-03
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
TIGR02169 :Pssm-ID: 481474 [Multi-domain]
Cd Length: 1164
Bit Score: 41.59
E-value: 1.72e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 69 ELNGQ L KYYQKQVGEM K LQ L ENVIK E NE R ------- L HS EL K DA VE K KL E AFPLGTEVGTDIYADD E TVRN L Q E Q L QLAN 141
Cdd:TIGR02169 671 SEPAE L QRLRERLEGL K RE L SSLQS E LR R ienrlde L SQ EL S DA SR K IG E IEKEIEQLEQEEEKLK E RLEE L E E D L SSLE 750
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 142 QE KTQAVELWQTVSQELDR L hklyqehmt E AQI H vfesq K QKDQ L F D FQQLTKQLHVTNENM E VTNQQ fl KT V TEQSVII 221
Cdd:TIGR02169 751 QE IENVKSELKELEARIEE L --------- E EDL H ----- K LEEA L N D LEARLSHSRIPEIQA E LSKLE -- EE V SRIEARL 814
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 222 EQLRK KL RQAK LE LRVAVAKVE EL TNVTE DL QG Q M K KK EK DVVSAH G RE E ASDRR L QQ L QSSIKQ LE I RL cvtiqea NQ L 301
Cdd:TIGR02169 815 REIEQ KL NRLT LE KEYLEKEIQ EL QEQRI DL KE Q I K SI EK EIENLN G KK E ELEEE L EE L EAALRD LE S RL ------- GD L 887
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 16549896 302 RT E NTH LE K Q T REL QA K CN ELE NERYEAIV R ARNSMQL LE EANLQK S Q ------ ALL E EKQK E EDI E KMKETVS R 370
Cdd:TIGR02169 888 KK E RDE LE A Q L REL ER K IE ELE AQIEKKRK R LSELKAK LE ALEEEL S E iedpkg EDE E IPEE E LSL E DVQAELQ R 962
Name
Accession
Description
Interval
E-value
Smc
COG1196 Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
221-687
1.09e-11
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain]
Cd Length: 983
Bit Score: 68.42
E-value: 1.09e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 221 IEQ L RKK L RQAKL EL RVAV A KV EEL TNVTED L QGQMKKKEKDVVSAHGRE E ASDRRLQQ L QSSIKQ LE IRLCVTIQEANQ 300
Cdd:COG1196 234 LRE L EAE L EELEA EL EELE A EL EEL EAELAE L EAELEELRLELEELELEL E EAQAEEYE L LAELAR LE QDIARLEERRRE 313
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 301 L RTENTH LE KQTR EL QAKCN ELE N E RY E AIVRARNSMQL LEEA NLQKSQ A LLEEKQK E EDIEKMK E TVSRFVQD -- ATI R 378
Cdd:COG1196 314 L EERLEE LE EELA EL EEELE ELE E E LE E LEEELEEAEEE LEEA EAELAE A EEALLEA E AELAEAE E ELEELAEE ll EAL R 393
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 379 TKK E V A NTKKQCNIQISR L T E E L SA L QM E CA E KQGQIERVIK E KKAV EE E LE KIYR E GRGN E CDYRK L E E MHQRF L VSER 458
Cdd:COG1196 394 AAA E L A AQLEELEEAEEA L L E R L ER L EE E LE E LEEALAELEE E EEEE EE A LE EAAE E EAEL E EEEEA L L E LLAEL L EEAA 473
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 459 SKDDLQLR L TRAENRIKQLETDSS E EISR Y QEMIQ -- K LQNV L ESE R ENC G L V SE ------------------------- 511
Cdd:COG1196 474 LLEAALAE L LEELAEAAARLLLLL E AEAD Y EGFLE gv K AALL L AGL R GLA G A V AV ligveaayeaaleaalaaalqnivv 553
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 512 ------- QRLKLQQEN K QL R KETES L R KI ALE A QKK A KVKISTMEHEFSIKE --- R GFEVQLREME D SNRNSIVELRH L L 581
Cdd:COG1196 554 eddevaa AAIEYLKAA K AG R ATFLP L D KI RAR A ALA A ALARGAIGAAVDLVA sdl R EADARYYVLG D TLLGRTLVAAR L E 633
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 582 A TQQK A ANRWKEETKKLT E SAEIRINNLKSEL SR QK L HTQE L LSQL E MANEKVAEN E KLILEHQEKANRLQRRLSQ AE ER 661
Cdd:COG1196 634 A ALRR A VTLAGRLREVTL E GEGGSAGGSLTGG SR RE L LAAL L EAEA E LEELAERLA E EELELEEALLAEEEEEREL AE AE 713
490 500
....*....|....*....|....*.
gi 16549896 662 AASASQQ L SVITVQRRKA A SLMN L EN 687
Cdd:COG1196 714 EERLEEE L EEEALEEQLE A EREE L LE 739
SMC_prok_A
TIGR02169 chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
338-683
4.00e-10
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain]
Cd Length: 1164
Bit Score: 63.16
E-value: 4.00e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 338 Q L LEEANL Q KSQA L LE E KQ K E E DIEKMKETVSRFVQDATIRT K KEVANT K KQCNI Q ISR L T EEL SA L QM E CA E KQGQI E R 417
Cdd:TIGR02169 190 D L IIDEKR Q QLER L RR E RE K A E RYQALLKEKREYEGYELLKE K EALERQ K EAIER Q LAS L E EEL EK L TE E IS E LEKRL E E 269
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 418 VIKEKKAVEEELEKI y R E GRGNECD y R K LE E MHQRFLVS ERS KDDLQLR L TR AE N R IKQ LE tdss E EI SRYQEM I QK L QN 497
Cdd:TIGR02169 270 IEQLLEELNKKIKDL - G E EEQLRVK - E K IG E LEAEIASL ERS IAEKERE L ED AE E R LAK LE ---- A EI DKLLAE I EE L ER 343
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 498 VL E S ER encglvs EQ R L KL QQ E NKQ L RK E T E S LR KIAL E AQ K KAK vkis TMEH E FSIKERGF E VQL RE MEDSN R nsiv EL 577
Cdd:TIGR02169 344 EI E E ER ------- KR R D KL TE E YAE L KE E L E D LR AELE E VD K EFA ---- ETRD E LKDYREKL E KLK RE INELK R ---- EL 408
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 578 RH L LATQ Q KAANRWKEETKKL t ESA E IR IN N L KS E LSRQK L HTQELLSQ LE MANEKVAEN E KLILEHQ E KAN R LQRR LS Q 657
Cdd:TIGR02169 409 DR L QEEL Q RLSEELADLNAAI - AGI E AK IN E L EE E KEDKA L EIKKQEWK LE QLAADLSKY E QELYDLK E EYD R VEKE LS K 487
330 340
....*....|....*....|....*...
gi 16549896 658 AEER -- A A S A SQQL S VIT V QRRK A ASLM 683
Cdd:TIGR02169 488 LQRE la E A E A QARA S EER V RGGR A VEEV 515
PTZ00121
PTZ00121 MAEBL; Provisional
155-662
2.74e-07
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain]
Cd Length: 2084
Bit Score: 54.38
E-value: 2.74e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 155 SQ E LDRLHKLYQE H MTEA Q IHVFESQKQ K DQLFDFQQLT K QLHVTNENM E VTNQQFL K TVT E QSVIIEQLR KK LRQ AK LE 234
Cdd:PTZ00121 1251 NE E IRKFEEARMA H FARR Q AAIKAEEAR K ADELKKAEEK K KADEAKKAE E KKKADEA K KKA E EAKKADEAK KK AEE AK KK 1330
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 235 LRV A VA K V EE LTNVT E DLQGQMKKKEKDVVS A HGRE EA SDRRLQQLQSSIKQLE i RLCVTIQE A NQLRTENTHLE K QTR E 314
Cdd:PTZ00121 1331 ADA A KK K A EE AKKAA E AAKAEAEAAADEAEA A EEKA EA AEKKKEEAKKKADAAK - KKAEEKKK A DEAKKKAEEDK K KAD E 1409
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 315 L QAK cn ELENERYEAIVRARNSMQLLE EA nlq K SQ A ll EE KQ K EEDIE K MK E tvsrfvqdatir TK K EVANT KK QC ni QI 394
Cdd:PTZ00121 1410 L KKA -- AAAKKKADEAKKKAEEKKKAD EA --- K KK A -- EE AK K ADEAK K KA E ------------ EA K KAEEA KK KA -- EE 1468
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 395 SRLTE E LSA l QM E C A E K QGQIERVIK E K K AVEE E LE K IYREGRGNE c DYR K L EE MHQRFLVSERSKDDLQLRLTR AE NRI 474
Cdd:PTZ00121 1469 AKKAD E AKK - KA E E A K K ADEAKKKAE E A K KKAD E AK K AAEAKKKAD - EAK K A EE AKKADEAKKAEEAKKADEAKK AE EKK 1546
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 475 K QL E TDSS EE ISRYQ E MIQKLQNVLES E RE N cglvse QR L KLQQ E N K QLRKETESLRKIAL E AQ KK A K VKISTMEH E FS I 554
Cdd:PTZ00121 1547 K AD E LKKA EE LKKAE E KKKAEEAKKAE E DK N ------ MA L RKAE E A K KAEEARIEEVMKLY E EE KK M K AEEAKKAE E AK I 1620
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 555 K ER gfev Q L REM E DS n RNSIVE L RHLL A TQQ K A A nrwk EE T KK LT E SAE I RINNLKSELSRQ K LHTQ E l LSQL E MANE K V 634
Cdd:PTZ00121 1621 K AE ---- E L KKA E EE - KKKVEQ L KKKE A EEK K K A ---- EE L KK AE E ENK I KAAEEAKKAEED K KKAE E - AKKA E EDEK K A 1690
490 500
....*....|....*....|....*...
gi 16549896 635 AE NE K LIL E HQE KA NR L QRRLSQAEER A 662
Cdd:PTZ00121 1691 AE AL K KEA E EAK KA EE L KKKEAEEKKK A 1718
CCCAP
pfam15964 Centrosomal colon cancer autoantigen protein family; CCCAP is a family of proteins found in ...
56-669
2.66e-06
Centrosomal colon cancer autoantigen protein family; CCCAP is a family of proteins found in eukaryotes. CCCAP is also known as SDCCAG8, serologically defined colon cancer antigen 8. It is associated with the centrosome.
Pssm-ID: 435040 [Multi-domain]
Cd Length: 703
Bit Score: 50.67
E-value: 2.66e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 56 L A P LVTEYDKHLGE L NGQL K YYQKQVG EMK LQLEN V IK ENE R L HS ELK D - AV E KK L EAFP L GTEV G T -- DIYADD E TV R N 132
Cdd:pfam15964 112 L V P IINDQSQYIHH L EAEV K FCKEELS EMK QRVQV V VL ENE K L QQ ELK S q TQ E ET L REQT L LDSS G N mq NSWCTP E DS R V 191
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 133 L Q EQLQL A NQEKTQAVELWQ T VSQ E LD RL HKLYQEHMT EA QIH V F ESQ kqkdqlfdfqqltkqlhvtnenmevtnqqflk 212
Cdd:pfam15964 192 H Q TSKRP A SHNLAERLKSAT T GED E KW RL ELEKLKLLY EA KTE V L ESQ -------------------------------- 239
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 213 tvteqsvi IEQ LRK K L rqaklelrvavakv E E LTNVT EDL QGQM K K KE K d V V S A HGREEASDRR L QQL Q SSIKQLEIRLC 292
Cdd:pfam15964 240 -------- VKS LRK D L -------------- A E SQKTC EDL KERL K H KE S - L V A A STSSRVGGLC L KCA Q HEAVLAQTHTN 296
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 293 V TI Q EANQ L RT E NTH L EKQTRELQAKCN E LENERYE A IVRARNSM Q LL EEAN LQ K SQ AL LEEK Q KEEDI E KM KE TVSRFV 372
Cdd:pfam15964 297 V HM Q TIER L TK E RDD L MSALVSVRSSLA E AQQRESS A YEQVKQAV Q MT EEAN FE K TK AL IQCE Q LKSEL E RQ KE RLEKEL 376
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 373 QDATIRTKK E VANTK K QCNIQISR L TEELS AL QMEC A EKQG Q I E R V IK EK KAVEEE LE KIYREGRGN E C D YR K L - E EM HQ 451
Cdd:pfam15964 377 ASQQEKRAQ E KEALR K EMKKEREE L GATML AL SQNV A QLEA Q V E K V TR EK NSLVSQ LE EAQKQLASQ E M D VT K V c G EM RY 456
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 452 RFLVSERS KD DLQLRLTRAENR - IK QLE TDSS E ------ E I S RYQEMIQKL Q NVLESE RE N C GLVS E QRLKLQQENKQL R 524
Cdd:pfam15964 457 QLNQTKMK KD EAEKEHREYRTK t GR QLE IKDQ E ieklgl E L S ESKQRLEQA Q QDAARA RE E C LKLT E LLGESEHQLHLT R 536
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 525 K E T ES LRKIALEAQ K KAKVKISTM E H E FSI K ergfevq LRE ME DSNRNSIV E LRH LL AT Q QKAANRW KEE TKK L TESA E I 604
Cdd:pfam15964 537 L E K ES IQQSFSNEA K AQALQAQQR E Q E LTQ K ------- MQQ ME AQHDKTVN E QYS LL TS Q NTFIAKL KEE CCT L AKKL E E 609
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 16549896 605 RINNLK SE LSRQKLHTQE L LSQ LE MANEKVA E N E KLILE H QEKAN R LQR RL S Q AEERAASAS QQL 669
Cdd:pfam15964 610 ITQKSR SE VEQLSQEKEY L QDR LE KLQKRNE E L E EQCVQ H GRMHE R MKQ RL R Q LDKHCQATA QQL 674
SMC_prok_A
TIGR02169 chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
69-370
1.72e-03
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain]
Cd Length: 1164
Bit Score: 41.59
E-value: 1.72e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 69 ELNGQ L KYYQKQVGEM K LQ L ENVIK E NE R ------- L HS EL K DA VE K KL E AFPLGTEVGTDIYADD E TVRN L Q E Q L QLAN 141
Cdd:TIGR02169 671 SEPAE L QRLRERLEGL K RE L SSLQS E LR R ienrlde L SQ EL S DA SR K IG E IEKEIEQLEQEEEKLK E RLEE L E E D L SSLE 750
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 142 QE KTQAVELWQTVSQELDR L hklyqehmt E AQI H vfesq K QKDQ L F D FQQLTKQLHVTNENM E VTNQQ fl KT V TEQSVII 221
Cdd:TIGR02169 751 QE IENVKSELKELEARIEE L --------- E EDL H ----- K LEEA L N D LEARLSHSRIPEIQA E LSKLE -- EE V SRIEARL 814
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 222 EQLRK KL RQAK LE LRVAVAKVE EL TNVTE DL QG Q M K KK EK DVVSAH G RE E ASDRR L QQ L QSSIKQ LE I RL cvtiqea NQ L 301
Cdd:TIGR02169 815 REIEQ KL NRLT LE KEYLEKEIQ EL QEQRI DL KE Q I K SI EK EIENLN G KK E ELEEE L EE L EAALRD LE S RL ------- GD L 887
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 16549896 302 RT E NTH LE K Q T REL QA K CN ELE NERYEAIV R ARNSMQL LE EANLQK S Q ------ ALL E EKQK E EDI E KMKETVS R 370
Cdd:TIGR02169 888 KK E RDE LE A Q L REL ER K IE ELE AQIEKKRK R LSELKAK LE ALEEEL S E iedpkg EDE E IPEE E LSL E DVQAELQ R 962
EnvC
COG4942 Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
87-288
4.69e-03
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain]
Cd Length: 377
Bit Score: 39.75
E-value: 4.69e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 87 Q LE NVIK E NER L HS EL KDAVEKKLEAFPLGTEVGTD I Y A DDETV R N L QEQ L QLANQ E KTQAVELWQTVSQ EL DRLHKLYQ 166
Cdd:COG4942 28 E LE QLQQ E IAE L EK EL AALKKEEKALLKQLAALERR I A A LARRI R A L EQE L AALEA E LAELEKEIAELRA EL EAQKEELA 107
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 167 E HMTEAQIH vfe SQKQKDQ L F ---- DF QQLTKQ L HVTNENMEVTNQ Q f LKTVTEQSVIIEQ LR KK L RQAKL EL RVAV A KV 242
Cdd:COG4942 108 E LLRALYRL --- GRQPPLA L L lspe DF LDAVRR L QYLKYLAPARRE Q - AEELRADLAELAA LR AE L EAERA EL EALL A EL 183
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 16549896 243 EE LT nvt ED L QGQMKKKE K DVVSAHGREEASDRR L QQ LQ SSIKQ LE 288
Cdd:COG4942 184 EE ER --- AA L EALKAERQ K LLARLEKELAELAAE L AE LQ QEAEE LE 226
CYP51-like
cd11042 cytochrome P450 family 51 and similar cytochrome P450s; This family is composed of cytochrome ...
56-100
7.81e-03
cytochrome P450 family 51 and similar cytochrome P450s; This family is composed of cytochrome P450 51 (CYP51 or sterol 14alpha-demethylase) and related cytochrome P450s. CYP51 is the only cytochrome P450 enzyme with a conserved function across animals, fungi, and plants, in the synthesis of essential sterols. In mammals, it is expressed in many different tissues, with highest expression in testis, ovary, adrenal gland, prostate, liver, kidney, and lung. In fungi, CYP51 is a significant drug target for treatment of human protozoan infections. In plants, it functions within a specialized defense-related metabolic pathway. CYP51 is also found in several bacterial species. This family belongs to the large cytochrome P450 (P450, CYP) superfamily of heme-containing proteins that catalyze a variety of oxidative reactions of a large number of structurally different endogenous and exogenous compounds in organisms from all major domains of life. CYPs bind their diverse ligands in a buried, hydrophobic active site, which is accessed through a substrate access channel formed by two flexible helices and their connecting loop.
Pssm-ID: 410668 [Multi-domain]
Cd Length: 416
Bit Score: 39.12
E-value: 7.81e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 16549896 56 L AP L VT E YDKH LG ELNGQ L K Y yq KQVG EM K L q L ENV IKE NE RLH S 100
Cdd:cd11042 246 L EA L RE E QKEV LG DGDDP L T Y -- DVLK EM P L - L HAC IKE TL RLH P 287
Name
Accession
Description
Interval
E-value
Smc
COG1196 Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
221-687
1.09e-11
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain]
Cd Length: 983
Bit Score: 68.42
E-value: 1.09e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 221 IEQ L RKK L RQAKL EL RVAV A KV EEL TNVTED L QGQMKKKEKDVVSAHGRE E ASDRRLQQ L QSSIKQ LE IRLCVTIQEANQ 300
Cdd:COG1196 234 LRE L EAE L EELEA EL EELE A EL EEL EAELAE L EAELEELRLELEELELEL E EAQAEEYE L LAELAR LE QDIARLEERRRE 313
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 301 L RTENTH LE KQTR EL QAKCN ELE N E RY E AIVRARNSMQL LEEA NLQKSQ A LLEEKQK E EDIEKMK E TVSRFVQD -- ATI R 378
Cdd:COG1196 314 L EERLEE LE EELA EL EEELE ELE E E LE E LEEELEEAEEE LEEA EAELAE A EEALLEA E AELAEAE E ELEELAEE ll EAL R 393
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 379 TKK E V A NTKKQCNIQISR L T E E L SA L QM E CA E KQGQIERVIK E KKAV EE E LE KIYR E GRGN E CDYRK L E E MHQRF L VSER 458
Cdd:COG1196 394 AAA E L A AQLEELEEAEEA L L E R L ER L EE E LE E LEEALAELEE E EEEE EE A LE EAAE E EAEL E EEEEA L L E LLAEL L EEAA 473
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 459 SKDDLQLR L TRAENRIKQLETDSS E EISR Y QEMIQ -- K LQNV L ESE R ENC G L V SE ------------------------- 511
Cdd:COG1196 474 LLEAALAE L LEELAEAAARLLLLL E AEAD Y EGFLE gv K AALL L AGL R GLA G A V AV ligveaayeaaleaalaaalqnivv 553
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 512 ------- QRLKLQQEN K QL R KETES L R KI ALE A QKK A KVKISTMEHEFSIKE --- R GFEVQLREME D SNRNSIVELRH L L 581
Cdd:COG1196 554 eddevaa AAIEYLKAA K AG R ATFLP L D KI RAR A ALA A ALARGAIGAAVDLVA sdl R EADARYYVLG D TLLGRTLVAAR L E 633
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 582 A TQQK A ANRWKEETKKLT E SAEIRINNLKSEL SR QK L HTQE L LSQL E MANEKVAEN E KLILEHQEKANRLQRRLSQ AE ER 661
Cdd:COG1196 634 A ALRR A VTLAGRLREVTL E GEGGSAGGSLTGG SR RE L LAAL L EAEA E LEELAERLA E EELELEEALLAEEEEEREL AE AE 713
490 500
....*....|....*....|....*.
gi 16549896 662 AASASQQ L SVITVQRRKA A SLMN L EN 687
Cdd:COG1196 714 EERLEEE L EEEALEEQLE A EREE L LE 739
Smc
COG1196 Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
224-542
3.54e-10
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain]
Cd Length: 983
Bit Score: 63.42
E-value: 3.54e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 224 LRKKLRQ A KLE L RVAVAKV E E L TNVTED L QG Q MKKK E KDVVS A hgreeasd R R LQQ L QSSI K Q LE IR L cv TIQEANQ L RT 303
Cdd:COG1196 170 YKERKEE A ERK L EATEENL E R L EDILGE L ER Q LEPL E RQAEK A -------- E R YRE L KEEL K E LE AE L -- LLLKLRE L EA 239
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 304 E NTH LE KQTR EL Q A KCN ELE N E RY E AIVRARNSMQL LEE AN L QKSQ A LL EE KQKEEDIEKMKETVS R FVQD atirt KK E V 383
Cdd:COG1196 240 E LEE LE AELE EL E A ELE ELE A E LA E LEAELEELRLE LEE LE L ELEE A QA EE YELLAELARLEQDIA R LEER ----- RR E L 314
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 384 ANTKKQCNIQISR L T EEL SA L QM E CA E KQGQI E RVIK E KKAV E E EL EKIYREGRGN E CDYRKL EE MHQRFLVSERSKDDL 463
Cdd:COG1196 315 EERLEELEEELAE L E EEL EE L EE E LE E LEEEL E EAEE E LEEA E A EL AEAEEALLEA E AELAEA EE ELEELAEELLEALRA 394
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 16549896 464 QLR L TRAENRIKQL E TDSS E EIS R YQ E MIQK L QNV L ESER E NCGLVS E QRLKLQQ E NKQ L RK E T E S L RKIAL E AQKK A K 542
Cdd:COG1196 395 AAE L AAQLEELEEA E EALL E RLE R LE E ELEE L EEA L AELE E EEEEEE E ALEEAAE E EAE L EE E E E A L LELLA E LLEE A A 473
SMC_prok_A
TIGR02169 chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
338-683
4.00e-10
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain]
Cd Length: 1164
Bit Score: 63.16
E-value: 4.00e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 338 Q L LEEANL Q KSQA L LE E KQ K E E DIEKMKETVSRFVQDATIRT K KEVANT K KQCNI Q ISR L T EEL SA L QM E CA E KQGQI E R 417
Cdd:TIGR02169 190 D L IIDEKR Q QLER L RR E RE K A E RYQALLKEKREYEGYELLKE K EALERQ K EAIER Q LAS L E EEL EK L TE E IS E LEKRL E E 269
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 418 VIKEKKAVEEELEKI y R E GRGNECD y R K LE E MHQRFLVS ERS KDDLQLR L TR AE N R IKQ LE tdss E EI SRYQEM I QK L QN 497
Cdd:TIGR02169 270 IEQLLEELNKKIKDL - G E EEQLRVK - E K IG E LEAEIASL ERS IAEKERE L ED AE E R LAK LE ---- A EI DKLLAE I EE L ER 343
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 498 VL E S ER encglvs EQ R L KL QQ E NKQ L RK E T E S LR KIAL E AQ K KAK vkis TMEH E FSIKERGF E VQL RE MEDSN R nsiv EL 577
Cdd:TIGR02169 344 EI E E ER ------- KR R D KL TE E YAE L KE E L E D LR AELE E VD K EFA ---- ETRD E LKDYREKL E KLK RE INELK R ---- EL 408
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 578 RH L LATQ Q KAANRWKEETKKL t ESA E IR IN N L KS E LSRQK L HTQELLSQ LE MANEKVAEN E KLILEHQ E KAN R LQRR LS Q 657
Cdd:TIGR02169 409 DR L QEEL Q RLSEELADLNAAI - AGI E AK IN E L EE E KEDKA L EIKKQEWK LE QLAADLSKY E QELYDLK E EYD R VEKE LS K 487
330 340
....*....|....*....|....*...
gi 16549896 658 AEER -- A A S A SQQL S VIT V QRRK A ASLM 683
Cdd:TIGR02169 488 LQRE la E A E A QARA S EER V RGGR A VEEV 515
SMC_prok_B
TIGR02168 chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
221-537
1.40e-09
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain]
Cd Length: 1179
Bit Score: 61.61
E-value: 1.40e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 221 IE Q L RK K LRQAKLELRVAVAKVE EL TNVT E D L QGQMKKKE K dvvsahg RE E ASD R RLQQ L QSSIKQ LE IRLCVTIQEAN Q 300
Cdd:TIGR02168 679 IE E L EE K IEELEEKIAELEKALA EL RKEL E E L EEELEQLR K ------- EL E ELS R QISA L RKDLAR LE AEVEQLEERIA Q 751
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 301 L RT E N T H LE KQTR EL QAKCN E L E N E RY EA IVRARNSMQLL E EANLQKSQ -- AL L E E KQK E EDIEK ------- MKETVSRF 371
Cdd:TIGR02168 752 L SK E L T E LE AEIE EL EERLE E A E E E LA EA EAEIEELEAQI E QLKEELKA lr EA L D E LRA E LTLLN eeaanlr ERLESLER 831
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 372 VQD AT I R TKKEVANTKKQCNIQ I SR L TE E LSA L QMECA E KQGQI E RVIK E KKAV EE E L EKIYR E GRGNECDY R K LE ---- 447
Cdd:TIGR02168 832 RIA AT E R RLEDLEEQIEELSED I ES L AA E IEE L EELIE E LESEL E ALLN E RASL EE A L ALLRS E LEELSEEL R E LE skrs 911
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 448 E MHQRFLVSERSKDD L Q LRL TRA E N RI KQ L ETDS SEE I S RYQ E MIQK L Q N VL E SER E ncglvseqrl KLQQEN K Q L RKET 527
Cdd:TIGR02168 912 E LRRELEELREKLAQ L E LRL EGL E V RI DN L QERL SEE Y S LTL E EAEA L E N KI E DDE E ---------- EARRRL K R L ENKI 981
330
....*....|
gi 16549896 528 ES L RKIA L E A 537
Cdd:TIGR02168 982 KE L GPVN L A A 991
Smc
COG1196 Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
125-655
3.78e-09
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain]
Cd Length: 983
Bit Score: 59.95
E-value: 3.78e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 125 ADDETVRN L QEQ L QLANQ E KTQAVELWQTVSQ EL DR L HKLYQ E HMT E AQIHVF E SQKQKDQLFDFQQLTKQ L HVTN E NM E 204
Cdd:COG1196 243 ELEAELEE L EAE L EELEA E LAELEAELEELRL EL EE L ELELE E AQA E EYELLA E LARLEQDIARLEERRRE L EERL E EL E 322
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 205 VTNQQFLKTVT E QSVII E Q L RKK L RQ A KL EL RV A V A KVE E LTNVTEDLQGQMKKK E KDVVSAHGREEASD R RLQQ L QSSI 284
Cdd:COG1196 323 EELAELEEELE E LEEEL E E L EEE L EE A EE EL EE A E A ELA E AEEALLEAEAELAEA E EELEELAEELLEAL R AAAE L AAQL 402
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 285 KQ LE IRLCVTIQEANQ L RT E NTH LE KQTR EL QAKCN E L E NERY EA IVRARNSMQLL E EANLQKSQA L L E EKQK E EDIEKM 364
Cdd:COG1196 403 EE LE EAEEALLERLER L EE E LEE LE EALA EL EEEEE E E E EALE EA AEEEAELEEEE E ALLELLAEL L E E AALL E AALAEL 482
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 365 K E TVSR fvqdatirt KKEVANTKKQ cn IQISRLTEELSALQMECAEKQGQIERVIKEKKA VE EEL E KIYREGRGNECDYR 444
Cdd:COG1196 483 L E ELAE --------- AAARLLLLLE -- AEADYEGFLEGVKAALLLAGLRGLAGAVAVLIG VE AAY E AALEAALAAALQNI 551
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 445 KL E EMHQRFLVS E RS K DDLQL R L T R - AENR I KQLETDSSEEISRYQEMIQK L QNVLES E RENCGL V SEQR L KLQQEN k QL 523
Cdd:COG1196 552 VV E DDEVAAAAI E YL K AAKAG R A T F l PLDK I RARAALAAALARGAIGAAVD L VASDLR E ADARYY V LGDT L LGRTLV - AA 630
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 524 R K E TESL R KIA L EAQKKAKVKISTMEHEFSIKER G FEVQ L REMEDSNRNSIV EL RHL LA TQQKAANRWKEETKKLTESAE 603
Cdd:COG1196 631 R L E AALR R AVT L AGRLREVTLEGEGGSAGGSLTG G SRRE L LAALLEAEAELE EL AER LA EEELELEEALLAEEEEERELA 710
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 16549896 604 IRINNLKS E LSRQKLHTQE L LSQL E MAN E KVA E N E K L IL E H -------------- QEKAN RL Q R RL 655
Cdd:COG1196 711 EAEEERLE E ELEEEALEEQ L EAER E ELL E ELL E E E E L LE E E aleelpeppdleel ERELE RL E R EI 776
SMC_prok_B
TIGR02168 chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
67-684
9.72e-08
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain]
Cd Length: 1179
Bit Score: 55.45
E-value: 9.72e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 67 L G EL NG QLK YYQK Q V -- G E MKLQ L ENVIK E N E R -- L HSE L KDAV E KKL E AFPLGT E VGTDIYADDETVRN L Q E Q L QLANQ 142
Cdd:TIGR02168 195 L N EL ER QLK SLER Q A ek A E RYKE L KAELR E L E L al L VLR L EELR E ELE E LQEELK E AEEELEELTAELQE L E E K L EELRL 274
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 143 E KTQ avelwqt VSQ E LDR L H K LYQEHMT E AQIHVFES Q KQKDQ L FDFQQLTKQ L HVTN E NM E VTNQQFLKTVT E QSVII E 222
Cdd:TIGR02168 275 E VSE ------- LEE E IEE L Q K ELYALAN E ISRLEQQK Q ILRER L ANLERQLEE L EAQL E EL E SKLDELAEELA E LEEKL E 347
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 223 Q L RKK L RQAKL EL RVAV A KV EEL TNVT E D L QG Q MKKKEKD V VSAHGREEASDRRLQQ L QSSIKQ LE I R LCVTI QE ANQ L R 302
Cdd:TIGR02168 348 E L KEE L ESLEA EL EELE A EL EEL ESRL E E L EE Q LETLRSK V AQLELQIASLNNEIER L EARLER LE D R RERLQ QE IEE L L 427
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 303 TENT hl E KQTR ELQA KCN ELE N E RY E AIVRARNSMQL LEE ANLQKSQ A LLEEKQK E EDIE ------ KMK E TVSRFVQDAT 376
Cdd:TIGR02168 428 KKLE -- E AELK ELQA ELE ELE E E LE E LQEELERLEEA LEE LREELEE A EQALDAA E RELA qlqarl DSL E RLQENLEGFS 505
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 377 i RTK K EVANTKKQCNIQISR L T E EL S ------------------ A LQM E CAEKQGQIERVI K EKK ---- AVEEELEKIYR 434
Cdd:TIGR02168 506 - EGV K ALLKNQSGLSGILGV L S E LI S vdegyeaaieaalggrlq A VVV E NLNAAKKAIAFL K QNE lgrv TFLPLDSIKGT 584
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 435 E GR GN ECDYR K LE E MHQRFLVSERSK D DL ----------------------- QLRLT R AEN RI KQ L ET D S - SEEISRYQE 490
Cdd:TIGR02168 585 E IQ GN DREIL K NI E GFLGVAKDLVKF D PK lrkalsyllggvlvvddldnale LAKKL R PGY RI VT L DG D L v RPGGVITGG 664
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 491 MIQKLQNV LE SE RE NCG L v S E QRLK L QQENKQ L R K ETES LRK i A LE AQKKAKVKISTMEH E F S IKERGFEVQ L REM E DSN 570
Cdd:TIGR02168 665 SAKTNSSI LE RR RE IEE L - E E KIEE L EEKIAE L E K ALAE LRK - E LE ELEEELEQLRKELE E L S RQISALRKD L ARL E AEV 742
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 571 RNSIVELRH L LATQQKAANRWK E ETKK L T E S ------ AE IR I NN L KSELSRQ K LHTQE L LSQ L EMANEKVAENEKLILEH 644
Cdd:TIGR02168 743 EQLEERIAQ L SKELTELEAEIE E LEER L E E A eeelae AE AE I EE L EAQIEQL K EELKA L REA L DELRAELTLLNEEAANL 822
650 660 670 680
....*....|....*....|....*....|....*....|
gi 16549896 645 Q E KANR L Q RR LSQA E E R AASASQ Q LSVITVQRRKA A SLMN 684
Cdd:TIGR02168 823 R E RLES L E RR IAAT E R R LEDLEE Q IEELSEDIESL A AEIE 862
PTZ00121
PTZ00121 MAEBL; Provisional
155-662
2.74e-07
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain]
Cd Length: 2084
Bit Score: 54.38
E-value: 2.74e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 155 SQ E LDRLHKLYQE H MTEA Q IHVFESQKQ K DQLFDFQQLT K QLHVTNENM E VTNQQFL K TVT E QSVIIEQLR KK LRQ AK LE 234
Cdd:PTZ00121 1251 NE E IRKFEEARMA H FARR Q AAIKAEEAR K ADELKKAEEK K KADEAKKAE E KKKADEA K KKA E EAKKADEAK KK AEE AK KK 1330
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 235 LRV A VA K V EE LTNVT E DLQGQMKKKEKDVVS A HGRE EA SDRRLQQLQSSIKQLE i RLCVTIQE A NQLRTENTHLE K QTR E 314
Cdd:PTZ00121 1331 ADA A KK K A EE AKKAA E AAKAEAEAAADEAEA A EEKA EA AEKKKEEAKKKADAAK - KKAEEKKK A DEAKKKAEEDK K KAD E 1409
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 315 L QAK cn ELENERYEAIVRARNSMQLLE EA nlq K SQ A ll EE KQ K EEDIE K MK E tvsrfvqdatir TK K EVANT KK QC ni QI 394
Cdd:PTZ00121 1410 L KKA -- AAAKKKADEAKKKAEEKKKAD EA --- K KK A -- EE AK K ADEAK K KA E ------------ EA K KAEEA KK KA -- EE 1468
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 395 SRLTE E LSA l QM E C A E K QGQIERVIK E K K AVEE E LE K IYREGRGNE c DYR K L EE MHQRFLVSERSKDDLQLRLTR AE NRI 474
Cdd:PTZ00121 1469 AKKAD E AKK - KA E E A K K ADEAKKKAE E A K KKAD E AK K AAEAKKKAD - EAK K A EE AKKADEAKKAEEAKKADEAKK AE EKK 1546
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 475 K QL E TDSS EE ISRYQ E MIQKLQNVLES E RE N cglvse QR L KLQQ E N K QLRKETESLRKIAL E AQ KK A K VKISTMEH E FS I 554
Cdd:PTZ00121 1547 K AD E LKKA EE LKKAE E KKKAEEAKKAE E DK N ------ MA L RKAE E A K KAEEARIEEVMKLY E EE KK M K AEEAKKAE E AK I 1620
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 555 K ER gfev Q L REM E DS n RNSIVE L RHLL A TQQ K A A nrwk EE T KK LT E SAE I RINNLKSELSRQ K LHTQ E l LSQL E MANE K V 634
Cdd:PTZ00121 1621 K AE ---- E L KKA E EE - KKKVEQ L KKKE A EEK K K A ---- EE L KK AE E ENK I KAAEEAKKAEED K KKAE E - AKKA E EDEK K A 1690
490 500
....*....|....*....|....*...
gi 16549896 635 AE NE K LIL E HQE KA NR L QRRLSQAEER A 662
Cdd:PTZ00121 1691 AE AL K KEA E EAK KA EE L KKKEAEEKKK A 1718
SMC_prok_B
TIGR02168 chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
302-657
1.06e-06
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain]
Cd Length: 1179
Bit Score: 52.37
E-value: 1.06e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 302 R T E NTH LE KQTR EL QA K CN ELE NERY E AIVRARNSMQL LE EANLQKSQALLEEKQKEE D IEKMKET V SRFVQDAT irtkk 381
Cdd:TIGR02168 676 R R E IEE LE EKIE EL EE K IA ELE KALA E LRKELEELEEE LE QLRKELEELSRQISALRK D LARLEAE V EQLEERIA ----- 750
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 382 evantkk Q CNIQISR L TE E LSA L QMECA E KQGQIERVIK E KKAV E EEL E KIYR E GRGNECDYRK L EEMHQR flvserskd 461
Cdd:TIGR02168 751 ------- Q LSKELTE L EA E IEE L EERLE E AEEELAEAEA E IEEL E AQI E QLKE E LKALREALDE L RAELTL --------- 814
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 462 d L QLRLTRAEN R IKQ LE tdss EE I SRYQEMIQK L QNVL E SER E NCGLVSEQRLK L QQENKQ L RK E T E S L rkia L EAQKKA 541
Cdd:TIGR02168 815 - L NEEAANLRE R LES LE ---- RR I AATERRLED L EEQI E ELS E DIESLAAEIEE L EELIEE L ES E L E A L ---- L NERASL 885
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 542 KVKISTMEH E FSIKER gfev Q LRE M E DSNRNSIV EL RH L LATQQKAAN R W keetkklt E SA E I RI N NL KSE LS rqklht Q 621
Cdd:TIGR02168 886 EEALALLRS E LEELSE ---- E LRE L E SKRSELRR EL EE L REKLAQLEL R L -------- E GL E V RI D NL QER LS ------ E 947
330 340 350
....*....|....*....|....*....|....*.
gi 16549896 622 E LLSQ LE M A NEKVAEN E KLIL E HQEKAN RL QRRLSQ 657
Cdd:TIGR02168 948 E YSLT LE E A EALENKI E DDEE E ARRRLK RL ENKIKE 983
COG4913
COG4913 Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
327-532
1.36e-06
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain]
Cd Length: 1089
Bit Score: 51.84
E-value: 1.36e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 327 Y EA IVR AR NSMQ LLE EAN l QKSQALLEEKQKEEDI E KMKETVSRFVQ datirtkkevantkkqc NIQISR L TE EL SA L QM 406
Cdd:COG4913 241 H EA LED AR EQIE LLE PIR - ELAERYAAARERLAEL E YLRAALRLWFA ----------------- QRRLEL L EA EL EE L RA 302
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 407 E C A EKQGQI ER VIKEKK A VE EEL EKIYREG RGN ec DYRK LE EMHQRFLVS ER SKDDLQL R LT R A E NRIKQ L ETDSSEEIS 486
Cdd:COG4913 303 E L A RLEAEL ER LEARLD A LR EEL DELEAQI RGN -- GGDR LE QLEREIERL ER ELEERER R RA R L E ALLAA L GLPLPASAE 380
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 16549896 487 RYQEMIQKLQNV LE SER E NCGLVS E QRLKLQQENKQ LR K E TES L RK 532
Cdd:COG4913 381 EFAALRAEAAAL LE ALE E ELEALE E ALAEAEAALRD LR R E LRE L EA 426
PTZ00121
PTZ00121 MAEBL; Provisional
62-556
1.50e-06
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain]
Cd Length: 2084
Bit Score: 51.68
E-value: 1.50e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 62 E YD K HLG E LNGQLKYYQ K QVG E M K LQL E NVIK E N E RLHS E LK d A V E K K L EA FPLGT E ---- VGTDIYADD E TVRNLQ E QL 137
Cdd:PTZ00121 1319 E AK K KAE E AKKKADAAK K KAE E A K KAA E AAKA E A E AAAD E AE - A A E E K A EA AEKKK E eakk KADAAKKKA E EKKKAD E AK 1397
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 138 QL A NQE K TQ A V EL WQTVS -- QEL D RLH K LYQ E -- HMT EA QIHVF E SQ K QKDQLFDFQQLT K QLHVTNENM E VTNQQFL K T 213
Cdd:PTZ00121 1398 KK A EED K KK A D EL KKAAA ak KKA D EAK K KAE E kk KAD EA KKKAE E AK K ADEAKKKAEEAK K AEEAKKKAE E AKKADEA K K 1477
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 214 VT E QSVIIEQLR KK LRQ AK LELRV A VAKV E ELTNVT E DLQGQMK KK EKDVVS A HGREE A SD rr LQQLQSSI K QL E IRLCV 293
Cdd:PTZ00121 1478 KA E EAKKADEAK KK AEE AK KKADE A KKAA E AKKKAD E AKKAEEA KK ADEAKK A EEAKK A DE -- AKKAEEKK K AD E LKKAE 1555
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 294 TIQE A NQLR - T E NTHLEKQTRELQAKCN E LENERY EA iv R ARNS M Q L L EE ANLQ K SQALL --- E E K Q K E E DIE K MK E tvs 369
Cdd:PTZ00121 1556 ELKK A EEKK k A E EAKKAEEDKNMALRKA E EAKKAE EA -- R IEEV M K L Y EE EKKM K AEEAK kae E A K I K A E ELK K AE E --- 1630
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 370 rf VQDATIRT KK EV A NT KK QCN i QISRLT EE LSALQM E C A E K QGQIERVIK E K K AV EE ELE K IYREGRGNECDYR K L EE M 449
Cdd:PTZ00121 1631 -- EKKKVEQL KK KE A EE KK KAE - ELKKAE EE NKIKAA E E A K K AEEDKKKAE E A K KA EE DEK K AAEALKKEAEEAK K A EE L 1707
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 450 HQR fl VS E RS K DDLQ L RLTRA EN R IK qletds S EE ISRYQ E MIQ K LQNVLESER E NCGLVSEQRLKLQQENKQL RKE T E S 529
Cdd:PTZ00121 1708 KKK -- EA E EK K KAEE L KKAEE EN K IK ------ A EE AKKEA E EDK K KAEEAKKDE E EKKKIAHLKKEEEKKAEEI RKE K E A 1779
490 500
....*....|....*....|....*..
gi 16549896 530 L rkia L E AQKKAKVKIST ME HEFS IK E 556
Cdd:PTZ00121 1780 V ---- I E EELDEEDEKRR ME VDKK IK D 1802
CCCAP
pfam15964 Centrosomal colon cancer autoantigen protein family; CCCAP is a family of proteins found in ...
56-669
2.66e-06
Centrosomal colon cancer autoantigen protein family; CCCAP is a family of proteins found in eukaryotes. CCCAP is also known as SDCCAG8, serologically defined colon cancer antigen 8. It is associated with the centrosome.
Pssm-ID: 435040 [Multi-domain]
Cd Length: 703
Bit Score: 50.67
E-value: 2.66e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 56 L A P LVTEYDKHLGE L NGQL K YYQKQVG EMK LQLEN V IK ENE R L HS ELK D - AV E KK L EAFP L GTEV G T -- DIYADD E TV R N 132
Cdd:pfam15964 112 L V P IINDQSQYIHH L EAEV K FCKEELS EMK QRVQV V VL ENE K L QQ ELK S q TQ E ET L REQT L LDSS G N mq NSWCTP E DS R V 191
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 133 L Q EQLQL A NQEKTQAVELWQ T VSQ E LD RL HKLYQEHMT EA QIH V F ESQ kqkdqlfdfqqltkqlhvtnenmevtnqqflk 212
Cdd:pfam15964 192 H Q TSKRP A SHNLAERLKSAT T GED E KW RL ELEKLKLLY EA KTE V L ESQ -------------------------------- 239
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 213 tvteqsvi IEQ LRK K L rqaklelrvavakv E E LTNVT EDL QGQM K K KE K d V V S A HGREEASDRR L QQL Q SSIKQLEIRLC 292
Cdd:pfam15964 240 -------- VKS LRK D L -------------- A E SQKTC EDL KERL K H KE S - L V A A STSSRVGGLC L KCA Q HEAVLAQTHTN 296
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 293 V TI Q EANQ L RT E NTH L EKQTRELQAKCN E LENERYE A IVRARNSM Q LL EEAN LQ K SQ AL LEEK Q KEEDI E KM KE TVSRFV 372
Cdd:pfam15964 297 V HM Q TIER L TK E RDD L MSALVSVRSSLA E AQQRESS A YEQVKQAV Q MT EEAN FE K TK AL IQCE Q LKSEL E RQ KE RLEKEL 376
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 373 QDATIRTKK E VANTK K QCNIQISR L TEELS AL QMEC A EKQG Q I E R V IK EK KAVEEE LE KIYREGRGN E C D YR K L - E EM HQ 451
Cdd:pfam15964 377 ASQQEKRAQ E KEALR K EMKKEREE L GATML AL SQNV A QLEA Q V E K V TR EK NSLVSQ LE EAQKQLASQ E M D VT K V c G EM RY 456
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 452 RFLVSERS KD DLQLRLTRAENR - IK QLE TDSS E ------ E I S RYQEMIQKL Q NVLESE RE N C GLVS E QRLKLQQENKQL R 524
Cdd:pfam15964 457 QLNQTKMK KD EAEKEHREYRTK t GR QLE IKDQ E ieklgl E L S ESKQRLEQA Q QDAARA RE E C LKLT E LLGESEHQLHLT R 536
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 525 K E T ES LRKIALEAQ K KAKVKISTM E H E FSI K ergfevq LRE ME DSNRNSIV E LRH LL AT Q QKAANRW KEE TKK L TESA E I 604
Cdd:pfam15964 537 L E K ES IQQSFSNEA K AQALQAQQR E Q E LTQ K ------- MQQ ME AQHDKTVN E QYS LL TS Q NTFIAKL KEE CCT L AKKL E E 609
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 16549896 605 RINNLK SE LSRQKLHTQE L LSQ LE MANEKVA E N E KLILE H QEKAN R LQR RL S Q AEERAASAS QQL 669
Cdd:pfam15964 610 ITQKSR SE VEQLSQEKEY L QDR LE KLQKRNE E L E EQCVQ H GRMHE R MKQ RL R Q LDKHCQATA QQL 674
CCDC158
pfam15921 Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
118-636
6.30e-06
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain]
Cd Length: 1112
Bit Score: 49.73
E-value: 6.30e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 118 E VG T D I YADDETVRNLQE QL QLANQ E KTQAV EL wq TVS Q EL DR LHK L YQ EH MT E AQIHVFESQKQKD Q LFDF Q Q ltk QL H 197
Cdd:pfam15921 228 E LD T E I SYLKGRIFPVED QL EALKS E SQNKI EL -- LLQ Q HQ DR IEQ L IS EH EV E ITGLTEKASSARS Q ANSI Q S --- QL E 302
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 198 VTN E NMEVT N QQFLKTVTEQSVIIE QLR KK LR Q AK lel R VAVA K V EEL TN -- V TEDLQGQMKKK E K D VV S AHGRE ea S D R 275
Cdd:pfam15921 303 IIQ E QARNQ N SMYMRQLSDLESTVS QLR SE LR E AK --- R MYED K I EEL EK ql V LANSELTEART E R D QF S QESGN -- L D D 377
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 276 R LQ Q L QSSIKQL E IR L CVTIQEANQ L RTEN T ---- HLEKQT REL QAK cn EL E NE R Y EA IVR A RN S mqlle E ANL Q KSQAL 351
Cdd:pfam15921 378 Q LQ K L LADLHKR E KE L SLEKEQNKR L WDRD T gnsi TIDHLR REL DDR -- NM E VQ R L EA LLK A MK S ----- E CQG Q MERQM 450
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 352 LEEKQ K E E DI EK MKETVSRFVQDATIRT K KEVAN T K K QCNIQI S RL T ee L S A L QMECA EK QGQ IE RVIK E KKAVEEELEK 431
Cdd:pfam15921 451 AAIQG K N E SL EK VSSLTAQLESTKEMLR K VVEEL T A K KMTLES S ER T -- V S D L TASLQ EK ERA IE ATNA E ITKLRSRVDL 528
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 432 iyreg RGN E CDYR K L E EM H Q R FLVS E rs KDD L Q L RLT raenrikql E T D SSE EI S R Y Q em I QKLQNVLESERENC G LVSE 511
Cdd:pfam15921 529 ----- KLQ E LQHL K N E GD H L R NVQT E -- CEA L K L QMA --------- E K D KVI EI L R Q Q -- I ENMTQLVGQHGRTA G AMQV 590
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 512 QRLK L QQ E NKQL R K E TESLR ki A L EAQ K K AK V ----- KI S TM E H E FSIKERGFEVQ LR EME D snrns I VEL R HL L ATQQ K 586
Cdd:pfam15921 591 EKAQ L EK E INDR R L E LQEFK -- I L KDK K D AK I relea RV S DL E L E KVKLVNAGSER LR AVK D ----- I KQE R DQ L LNEV K 663
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|
gi 16549896 587 AA nrw KE E TKK L T E SA E IRIN N LKSELSRQKLH T QE L LS QL EM A NEKVAE 636
Cdd:pfam15921 664 TS --- RN E LNS L S E DY E VLKR N FRNKSEEMETT T NK L KM QL KS A QSELEQ 710
SMC_prok_B
TIGR02168 chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
87-359
4.54e-05
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain]
Cd Length: 1179
Bit Score: 46.97
E-value: 4.54e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 87 Q LE NV I K E N E RLHS EL KD A VEKKLEAFPLGT E VGTDIYADD E TVRNLQEQ L QLANQEKTQA VE LWQTVSQE L DRLHKLYQ 166
Cdd:TIGR02168 681 E LE EK I E E L E EKIA EL EK A LAELRKELEELE E ELEQLRKEL E ELSRQISA L RKDLARLEAE VE QLEERIAQ L SKELTELE 760
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 167 EHMT E AQIHVF E SQKQKDQLFD - FQQ L TK Q LHVTN E NMEVTNQQF lktv T E QSVIIEQ L RKKLRQAKLE L RVAVAKVEEL 245
Cdd:TIGR02168 761 AEIE E LEERLE E AEEELAEAEA e IEE L EA Q IEQLK E ELKALREAL ---- D E LRAELTL L NEEAANLRER L ESLERRIAAT 836
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 246 TNVT EDL QG Q MKKKEK D VV S AHGRE E ASDRRLQQ L Q S SIKQ L EIRLCVTIQEANQ LR T E NTH L EKQT REL QA K CN EL EN E 325
Cdd:TIGR02168 837 ERRL EDL EE Q IEELSE D IE S LAAEI E ELEELIEE L E S ELEA L LNERASLEEALAL LR S E LEE L SEEL REL ES K RS EL RR E 916
250 260 270
....*....|....*....|....*....|....
gi 16549896 326 RY E A ivrarns MQL L EEAN L QKSQALLEEKQKE E 359
Cdd:TIGR02168 917 LE E L ------- REK L AQLE L RLEGLEVRIDNLQ E 943
DUF5401
pfam17380 Family of unknown function (DUF5401); This is a family of unknown function found in ...
353-678
5.64e-05
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain]
Cd Length: 722
Bit Score: 46.27
E-value: 5.64e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 353 E EKQKEEDIEKMK E T V SRFVQDA T I R TKKEVANTKKQC N -- IQ I SRLTEEL S AL Q MECAEKQGQI ER VIK EK KAVEE E L E 430
Cdd:pfam17380 234 E KMERRKESFNLA E D V TTMTPEY T V R YNGQTMTENEFL N ql LH I VQHQKAV S ER Q QQEKFEKMEQ ER LRQ EK EEKAR E V E 313
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 431 KIYREGRGNECDYRKLEEMHQRFLVS ER skdd LQLRLT R AEN RI K Q L E TDSSE E IS R YQ E MIQKLQNVL E S ER encglvs 510
Cdd:pfam17380 314 RRRKLEEAEKARQAEMDRQAAIYAEQ ER ---- MAMERE R ELE RI R Q E E RKREL E RI R QE E IAMEISRMR E L ER ------- 382
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 511 e QRLKL QQ E N KQL R K E T E SL RK IAL --- E A Q K K AKVKIST ME HEFSIK E RGFEVQL R EM E D -------------- SNRNS 573
Cdd:pfam17380 383 - LQMER QQ K N ERV R Q E L E AA RK VKI lee E R Q R K IQQQKVE ME QIRAEQ E EARQREV R RL E E eraremervrleeq ERQQQ 461
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 574 IVE LR HLLATQQKAANRWKE E TKKLTESA E I R INN L KS EL SRQ K LHTQ E LLSQLEMANEKVA E NE K L I L E HQEKANRLQR 653
Cdd:pfam17380 462 VER LR QQEEERKRKKLELEK E KRDRKRAE E Q R RKI L EK EL EER K QAMI E EERKRKLLEKEME E RQ K A I Y E EERRREAEEE 541
330 340
....*....|....*....|....*.
gi 16549896 654 R LS Q A E - E RAASASQ Q LSVI T VQ R RK 678
Cdd:pfam17380 542 R RK Q Q E m E ERRRIQE Q MRKA T EE R SR 567
SMC_prok_A
TIGR02169 chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
60-428
1.67e-04
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain]
Cd Length: 1164
Bit Score: 45.06
E-value: 1.67e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 60 V T E Y D KHLGELNGQ L KYYQKQVGEMK L QLENVIK ----- EN ER LHS E LKD A VE K KLEAFP l G T E VGTDIY A DDETVRNLQ 134
Cdd:TIGR02169 165 V A E F D RKKEKALEE L EEVEENIERLD L IIDEKRQ qlerl RR ER EKA E RYQ A LL K EKREYE - G Y E LLKEKE A LERQKEAIE 243
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 135 E QL QLANQ E KTQAV E LWQTVSQE L DRLHK L YQ E hm TEAQ I HVFESQK Q KDQLFDFQQ L TKQLHVTNENMEVTNQQ flktv 214
Cdd:TIGR02169 244 R QL ASLEE E LEKLT E EISELEKR L EEIEQ L LE E -- LNKK I KDLGEEE Q LRVKEKIGE L EAEIASLERSIAEKERE ----- 316
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 215 teqsvi I E QLRKK L RQAKL E LRVAV A KV EEL TNVT E DLQGQMK K KEKDVVSAHGRE E ASDRR L QQLQSS ------- I K QL 287
Cdd:TIGR02169 317 ------ L E DAEER L AKLEA E IDKLL A EI EEL EREI E EERKRRD K LTEEYAELKEEL E DLRAE L EEVDKE faetrde L K DY 390
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 288 EIR L CVTIQ E A N Q L RT E NTH L EKQTRE L QAKCNE L ENE ryea I VRARNSMQL LEE ANLQ K SQALLEEKQ K E E DIEKMKET 367
Cdd:TIGR02169 391 REK L EKLKR E I N E L KR E LDR L QEELQR L SEELAD L NAA ---- I AGIEAKINE LEE EKED K ALEIKKQEW K L E QLAADLSK 466
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 16549896 368 VSR fvqdatirtkkevantkkqcni QISR L T EE LSALQM E CAEK Q GQIERVIKEKK A V EE E 428
Cdd:TIGR02169 467 YEQ ---------------------- ELYD L K EE YDRVEK E LSKL Q RELAEAEAQAR A S EE R 505
CCDC158
pfam15921 Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
53-549
2.36e-04
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain]
Cd Length: 1112
Bit Score: 44.72
E-value: 2.36e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 53 Q SFLAP L VT E YDKHLGE L NGQLKYYQK Q VGEMKL QLE n V I K E NE R LHSELKDAVEKK LE AF -- P L GT E VGTDIYADDETV 130
Cdd:pfam15921 266 Q DRIEQ L IS E HEVEITG L TEKASSARS Q ANSIQS QLE - I I Q E QA R NQNSMYMRQLSD LE ST vs Q L RS E LREAKRMYEDKI 344
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 131 RN L QE QL Q LAN Q E K T Q A VELWQTV SQE L ---- D R L H KL YQE - H MT E AQIHVFES Q KQKDQLF D FQQLTKQL H VTN E ---- 201
Cdd:pfam15921 345 EE L EK QL V LAN S E L T E A RTERDQF SQE S gnld D Q L Q KL LAD l H KR E KELSLEKE Q NKRLWDR D TGNSITID H LRR E lddr 424
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 202 NMEV TN - QQF LK TVTEQSVIIEQLRKKLR Q A K L E lrv AVA KV EE LT NVT E DLQGQMK K KEKDVVSAHGRE E A S D R RLQQ L 280
Cdd:pfam15921 425 NMEV QR l EAL LK AMKSECQGQMERQMAAI Q G K N E --- SLE KV SS LT AQL E STKEMLR K VVEELTAKKMTL E S S E R TVSD L 501
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 281 QS S -------------- I KQ L EI R LCVTI QE ANQ L RT E NT HL EKQTR E LQ A - K CNEL E NERYEA I V R AR -- N SM QL LEEA 343
Cdd:pfam15921 502 TA S lqekeraieatnae I TK L RS R VDLKL QE LQH L KN E GD HL RNVQT E CE A l K LQMA E KDKVIE I L R QQ ie N MT QL VGQH 581
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 344 NLQKSQALL E EK Q K E ED I EKMKETV srfvqdatirtk K E VANT K KQCNIQ I SR L TEEL S A L QM E CAEKQGQIERVIKEK K 423
Cdd:pfam15921 582 GRTAGAMQV E KA Q L E KE I NDRRLEL ------------ Q E FKIL K DKKDAK I RE L EARV S D L EL E KVKLVNAGSERLRAV K 649
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 424 AVEE E LEKIYR E GRGNECDYRK L E E MHQRFLVSE R S K DD ---------- L QL RLTRA E ----- N RI K QL E ---------- 478
Cdd:pfam15921 650 DIKQ E RDQLLN E VKTSRNELNS L S E DYEVLKRNF R N K SE emetttnklk M QL KSAQS E leqtr N TL K SM E gsdghamkva 729
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 479 ------- T DSSEE I SRY Q EM IQ K L QNVLESERENCGLVS E QRL KL Q QE NKQLRK E TESLR --- KIALEAQKKA K V K IST M 548
Cdd:pfam15921 730 mgmqkqi T AKRGQ I DAL Q SK IQ F L EEAMTNANKEKHFLK E EKN KL S QE LSTVAT E KNKMA gel EVLRSQERRL K E K VAN M 809
.
gi 16549896 549 E 549
Cdd:pfam15921 810 E 810
COG2433
COG2433 Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
415-534
4.13e-04
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain]
Cd Length: 644
Bit Score: 43.69
E-value: 4.13e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 415 I E RV I KEKKAV EE ELEKIYR E GRGN E CD ----- Y R K LEE MHQ R f L VS E RS kd D L QLR L TRAEN RI KQ LE TDS SE ------ 483
Cdd:COG2433 382 L E EL I EKELPE EE PEAEREK E HEER E LT eeeee I R R LEE QVE R - L EA E VE -- E L EAE L EEKDE RI ER LE REL SE arseer 458
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 16549896 484 ------- EISR YQEM I QK L QNV LE S ERE ncglvseqrlklqq ENKQ L RKET E S L RKIA 534
Cdd:COG2433 459 reirkdr EISR LDRE I ER L ERE LE E ERE -------------- RIEE L KRKL E R L KELW 502
EnvC
COG4942 Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
210-435
7.35e-04
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain]
Cd Length: 377
Bit Score: 42.44
E-value: 7.35e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 210 FLKTVTE Q SVIIEQLRKK L R Q AKL E LRVAVAKVEE L TNVTED L QG Q MK kkekdvvsahgree A SD RR LQQ L QSS I KQ LE I 289
Cdd:COG4942 11 LALAAAA Q ADAAAEAEAE L E Q LQQ E IAELEKELAA L KKEEKA L LK Q LA -------------- A LE RR IAA L ARR I RA LE Q 76
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 290 R L CVTIQ E ANQ L RT E NTH L EKQTRELQAKCN EL ENER Y -------------- E AIVR A RNSM Q L L EEANLQKSQALL E EK 355
Cdd:COG4942 77 E L AALEA E LAE L EK E IAE L RAELEAQKEELA EL LRAL Y rlgrqpplalllsp E DFLD A VRRL Q Y L KYLAPARREQAE E LR 156
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 356 QKEEDIEKMKETVSR f VQDATIRTKK E VANTKKQCNIQISRLTEE L SA L QM E C AE KQGQIERVIK E KKAV E EELEKIYR E 435
Cdd:COG4942 157 ADLAELAALRAELEA - ERAELEALLA E LEEERAALEALKAERQKL L AR L EK E L AE LAAELAELQQ E AEEL E ALIARLEA E 235
PRK02224
PRK02224 DNA double-strand break repair Rad50 ATPase;
309-670
9.73e-04
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain]
Cd Length: 880
Bit Score: 42.33
E-value: 9.73e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 309 EK QTRE L QAKC N E LE N E RY E -- AIVRARNSMQLLEEANLQKSQAL LEE - KQKE E DI E KMKETVSRFVQD -- A T I R TKK E V 383
Cdd:PRK02224 198 EK EEKD L HERL N G LE S E LA E ld EEIERYEEQREQARETRDEADEV LEE h EERR E EL E TLEAEIEDLRET ia E T E R ERE E L 277
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 384 A NTKKQCNIQISR L T EE LSA L QM E CAEKQGQI E R V IKEKKAV E EEL E KIYREGR gnec DY R KLEEM H QRFLV S E R SK - DD 462
Cdd:PRK02224 278 A EEVRDLRERLEE L E EE RDD L LA E AGLDDADA E A V EARREEL E DRD E ELRDRLE ---- EC R VAAQA H NEEAE S L R ED a DD 353
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 463 L QL R LTRAENRIKQ LE TD --- SS E EISRYQ E M I QK L QNVL E SE RE NC G LVSEQRLKLQQENKQ LR K E TES LR K ialeaqk 539
Cdd:PRK02224 354 L EE R AEELREEAAE LE SE lee AR E AVEDRR E E I EE L EEEI E EL RE RF G DAPVDLGNAEDFLEE LR E E RDE LR E ------- 426
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 540 kakvkistmehefsi K E RGF E VQ LR EM edsn R NSIV E LRH LL A tqqka A NRWK E ETKKLTE S -------- AEI R INN L KS 611
Cdd:PRK02224 427 --------------- R E AEL E AT LR TA ---- R ERVE E AEA LL E ----- A GKCP E CGQPVEG S phvetiee DRE R VEE L EA 482
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 16549896 612 EL SRQKLHTQ E LLSQ LE M A n E KVA E N E KL I LEHQ E KANR L QRRLSQAE E RAASASQQLS 670
Cdd:PRK02224 483 EL EDLEEEVE E VEER LE R A - E DLV E A E DR I ERLE E RRED L EELIAERR E TIEEKRERAE 540
PTZ00121
PTZ00121 MAEBL; Provisional
171-661
1.10e-03
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain]
Cd Length: 2084
Bit Score: 42.44
E-value: 1.10e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 171 EA QI HV FESQKQ K DQLF DF QQLT K QLHVTN E NM E VTNQQFLKTVTEQSVII E QL RK KLRQA K L -------- E L R V A -- VA 240
Cdd:PTZ00121 1061 EA KA HV GQDEGL K PSYK DF DFDA K EDNRAD E AT E EAFGKAEEAKKTETGKA E EA RK AEEAK K K aedarkae E A R K A ed AR 1140
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 241 K V EE LTNVTEDLQGQMKK K EK D VVS A HGREE A S D RR lq QLQSSI K QL E I R LCVTIQE A NQL R TEN thlekqtrelqakcn 320
Cdd:PTZ00121 1141 K A EE ARKAEDAKRVEIAR K AE D ARK A EEARK A E D AK -- KAEAAR K AE E V R KAEELRK A EDA R KAE --------------- 1203
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 321 el ENERY E AIVR A RNSMQLLEEANLQKSQALL E E K QKE E DI ----- E KMK E TVSR F VQDATIRTKKEV A NT K --- KQCNI 392
Cdd:PTZ00121 1204 -- AARKA E EERK A EEARKAEDAKKAEAVKKAE E A K KDA E EA kkaee E RNN E EIRK F EEARMAHFARRQ A AI K aee ARKAD 1281
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 393 QISRLT E ELS A LQMEC AE KQGQIERVI K --- E K K AVE E ELE K IYREGRGNECDYR K L EE MHQRFLVSERSKDDLQLRLTR 469
Cdd:PTZ00121 1282 ELKKAE E KKK A DEAKK AE EKKKADEAK K kae E A K KAD E AKK K AEEAKKKADAAKK K A EE AKKAAEAAKAEAEAAADEAEA 1361
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 470 AE NRIKQL E TDSS E EISRYQEMIQ K LQNVLESER ----- E NCGLVSEQRL K LQQEN K --- QLR K ET E SLR K i A L EA Q KKA 541
Cdd:PTZ00121 1362 AE EKAEAA E KKKE E AKKKADAAKK K AEEKKKADE akkka E EDKKKADELK K AAAAK K kad EAK K KA E EKK K - A D EA K KKA 1440
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 542 KVKISTM E HEFSIK E - RGF E VQLREM E DSNRNSIVELRHLL A TQQKA A NRWK EE T KK LTES A EIRINNL K SELSRQ K LHT 620
Cdd:PTZ00121 1441 EEAKKAD E AKKKAE E a KKA E EAKKKA E EAKKADEAKKKAEE A KKADE A KKKA EE A KK KADE A KKAAEAK K KADEAK K AEE 1520
490 500 510 520
....*....|....*....|....*....|....*....|...
gi 16549896 621 QELLSQLEM A N E KVAEN E KLIL E HQE KA NR L QR -- R L SQ AEE R 661
Cdd:PTZ00121 1521 AKKADEAKK A E E AKKAD E AKKA E EKK KA DE L KK ae E L KK AEE K 1563
COG4913
COG4913 Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
393-659
1.15e-03
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain]
Cd Length: 1089
Bit Score: 42.21
E-value: 1.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 393 QISR L TE EL SA L QM E C AE KQGQI E RVIK E KK A VE E EL E kiyregrgnec DYRK L E E mhqr FLVS E RSKDDLQLRLTRA E N 472
Cdd:COG4913 611 KLAA L EA EL AE L EE E L AE AEERL E ALEA E LD A LQ E RR E ----------- ALQR L A E ---- YSWD E IDVASAEREIAEL E A 675
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 473 RIKQ L ETD S S e EISRYQ E MIQK L QNV LE SER E NCGLVSEQRLK L QQ E NK Q LRK E TES L RKIALE A QKK A KV kistm E HEF 552
Cdd:COG4913 676 ELER L DAS S D - DLAALE E QLEE L EAE LE ELE E ELDELKGEIGR L EK E LE Q AEE E LDE L QDRLEA A EDL A RL ----- E LRA 749
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 553 SIK ER GFEVQLREM E D snrnsiv ELR HL L ATQQK A ANR wkeetkk LTES AE IRINNLKSE - LSRQKLH T QE L LSQ LE MAN 631
Cdd:COG4913 750 LLE ER FAAALGDAV E R ------- ELR EN L EERID A LRA ------- RLNR AE EELERAMRA f NREWPAE T AD L DAD LE SLP 815
250 260 270
....*....|....*....|....*....|..
gi 16549896 632 E KV A ENEK L ---- IL E HQ E KANR L QRRL S QAE 659
Cdd:COG4913 816 E YL A LLDR L eedg LP E YE E RFKE L LNEN S IEF 847
DUF3584
pfam12128 Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
53-544
1.48e-03
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain]
Cd Length: 1191
Bit Score: 42.13
E-value: 1.48e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 53 Q SFLAP L VTEYDKHLG E L N GQLKYYQKQV GE M KL Q L ENVI ----- KENERLHS E LKDAVEKKL EA FPLGT E VGTD iya DD 127
Cdd:pfam12128 418 Q ALESE L REQLEAGKL E F N EEEYRLKSRL GE L KL R L NQAT atpel LLQLENFD E RIERAREEQ EA ANAEV E RLQS --- EL 494
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 128 ETV R NLQE Q LQL A NQEKTQAV E LW Q TVSQ EL drlhklyq E HMTEA Q IH vfesqkqkd Q L FD F QQLTKQLHVTNENMEVTN 207
Cdd:pfam12128 495 RQA R KRRD Q ASE A LRQASRRL E ER Q SALD EL -------- E LQLFP Q AG --------- T L LH F LRKEAPDWEQSIGKVISP 557
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 208 QQFLK T VTEQS V IIEQLRKK L RQAKLE L RVAVAK V E E LTNVT E D L QGQMK K K E KDVV SA HGREE A SDRR L Q Q LQSSIKQL 287
Cdd:pfam12128 558 ELLHR T DLDPE V WDGSVGGE L NLYGVK L DLKRID V P E WAASE E E L RERLD K A E EALQ SA REKQA A AEEQ L V Q ANGELEKA 637
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 288 EIRLCVTIQEANQL R TENTH L EKQTRELQA K C N ELEN ER YEAIVRAR NS MQLLEEANLQ K S QA L LEE KQKE ediekmket 367
Cdd:pfam12128 638 SREETFARTALKNA R LDLRR L FDEKQSEKD K K N KALA ER KDSANERL NS LEAQLKQLDK K H QA W LEE QKEQ --------- 708
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 368 v S R FVQDATIRTKKE V ANTKK qcn I Q ISR L TEELS A LQMECAEKQGQI E RVI K - EKKAVEEELEK I YREG R GNECDY RK L 446
Cdd:pfam12128 709 - K R EARTEKQAYWQV V EGALD --- A Q LAL L KAAIA A RRSGAKAELKAL E TWY K r DLASLGVDPDV I AKLK R EIRTLE RK I 784
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 447 E EMHQ R FLVSE R SK D DL Q LRLTRAEN R IKQLETDSSEE IS RY Q EMIQK L QN vl ESERENCG L VS E qrlk LQQEN KQ LRKE 526
Cdd:pfam12128 785 E RIAV R RQEVL R YF D WY Q ETWLQRRP R LATQLSNIERA IS EL Q QQLAR L IA -- DTKLRRAK L EM E ---- RKASE KQ QVRL 858
490
....*....|....*...
gi 16549896 527 T E S LR KIAL E AQ K K A KV K 544
Cdd:pfam12128 859 S E N LR GLRC E MS K L A TL K 876
SMC_prok_A
TIGR02169 chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
69-370
1.72e-03
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain]
Cd Length: 1164
Bit Score: 41.59
E-value: 1.72e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 69 ELNGQ L KYYQKQVGEM K LQ L ENVIK E NE R ------- L HS EL K DA VE K KL E AFPLGTEVGTDIYADD E TVRN L Q E Q L QLAN 141
Cdd:TIGR02169 671 SEPAE L QRLRERLEGL K RE L SSLQS E LR R ienrlde L SQ EL S DA SR K IG E IEKEIEQLEQEEEKLK E RLEE L E E D L SSLE 750
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 142 QE KTQAVELWQTVSQELDR L hklyqehmt E AQI H vfesq K QKDQ L F D FQQLTKQLHVTNENM E VTNQQ fl KT V TEQSVII 221
Cdd:TIGR02169 751 QE IENVKSELKELEARIEE L --------- E EDL H ----- K LEEA L N D LEARLSHSRIPEIQA E LSKLE -- EE V SRIEARL 814
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 222 EQLRK KL RQAK LE LRVAVAKVE EL TNVTE DL QG Q M K KK EK DVVSAH G RE E ASDRR L QQ L QSSIKQ LE I RL cvtiqea NQ L 301
Cdd:TIGR02169 815 REIEQ KL NRLT LE KEYLEKEIQ EL QEQRI DL KE Q I K SI EK EIENLN G KK E ELEEE L EE L EAALRD LE S RL ------- GD L 887
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 16549896 302 RT E NTH LE K Q T REL QA K CN ELE NERYEAIV R ARNSMQL LE EANLQK S Q ------ ALL E EKQK E EDI E KMKETVS R 370
Cdd:TIGR02169 888 KK E RDE LE A Q L REL ER K IE ELE AQIEKKRK R LSELKAK LE ALEEEL S E iedpkg EDE E IPEE E LSL E DVQAELQ R 962
hsdR
PRK11448 type I restriction enzyme EcoKI subunit R; Provisional
593-685
1.97e-03
type I restriction enzyme EcoKI subunit R; Provisional
Pssm-ID: 236912 [Multi-domain]
Cd Length: 1123
Bit Score: 41.48
E-value: 1.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 593 E ETKK L TESAEIRINN LK SE L SR Q KLHTQELLSQL E MANEKVAEN E K L IL E HQ EK ANR L QRR L S Q AE E R AA SA SQ QLSVI 672
Cdd:PRK11448 138 E DPEN L LHALQQEVLT LK QQ L EL Q AREKAQSQALA E AQQQELVAL E G L AA E LE EK QQE L EAQ L E Q LQ E K AA ET SQ ERKQK 217
90
....*....|....
gi 16549896 673 TVQR - RK AA SLMN L 685
Cdd:PRK11448 218 RKEI t DQ AA KRLE L 231
EnvC
COG4942 Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
580-669
2.30e-03
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain]
Cd Length: 377
Bit Score: 40.90
E-value: 2.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 580 LLA TQQK A ANRWKE E TKKLT E SAEIR I NN L KS EL SRQ K LHTQE LL S QL EMANEKV A ENEKL I LEHQEKANR L QRR L SQA E 659
Cdd:COG4942 10 LLA LAAA A QADAAA E AEAEL E QLQQE I AE L EK EL AAL K KEEKA LL K QL AALERRI A ALARR I RALEQELAA L EAE L AEL E 89
90
....*....|
gi 16549896 660 ERA A SASQQ L 669
Cdd:COG4942 90 KEI A ELRAE L 99
235kDa-fam
TIGR01612 reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
344-525
2.37e-03
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain]
Cd Length: 2757
Bit Score: 41.58
E-value: 2.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 344 NLQ KS QALLE E KQ K - EED IEK M KE TVSRFVQ D A T -------- IRT K KEV A N TKK QCN I Q I SRLTEELSALQM E CAEKQGQ 414
Cdd:TIGR01612 1491 HID KS KGCKD E AD K n AKA IEK N KE LFEQYKK D V T ellnkysa LAI K NKF A K TKK DSE I I I KEIKDAHKKFIL E AEKSEQK 1570
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 415 I ERVI KEK KAV E EELE K IYREGRGNECDYRK LE EMHQR FL -- VSERS K DDLQ L RL T RA - E NR I KQLET DS SE - E ISRYQE 490
Cdd:TIGR01612 1571 I KEIK KEK FRI E DDAA K NDKSNKAAIDIQLS LE NFENK FL ki SDIKK K INDC L KE T ES i E KK I SSFSI DS QD t E LKENGD 1650
170 180 190
....*....|....*....|....*....|....*
gi 16549896 491 MIQK LQ NV LES ERENCGLVSEQRLK L QQENKQLR K 525
Cdd:TIGR01612 1651 NLNS LQ EF LES LKDQKKNIEDKKKE L DELDSEIE K 1685
DUF3584
pfam12128 Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
277-679
2.47e-03
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain]
Cd Length: 1191
Bit Score: 41.36
E-value: 2.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 277 LQQ LQSSIKQL E I RL C vtiqean Q L RTENTHL E KQTREL Q AKCN E LEN E RYEAIVRARNSM - QLLE E A N LQK S Q A LLEEK 355
Cdd:pfam12128 246 LQQ EFNTLESA E L RL S ------- H L HFGYKSD E TLIASR Q EERQ E TSA E LNQLLRTLDDQW k EKRD E L N GEL S A A DAAVA 318
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 356 QKEEDI E KMKETVSR F v Q DA T I R T KKEVANTKKQCNIQISR L T E E L S AL Q meca E K QGQIERVIKEKKAV eeelekiyre 435
Cdd:pfam12128 319 KDRSEL E ALEDQHGA F - L DA D I E T AAADQEQLPSWQSELEN L E E R L K AL T ---- G K HQDVTAKYNRRRSK ---------- 383
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 436 g RGNECD y R KLEEMHQR flv SERSKDDLQLR L TR AE NRIKQ LE TDSS E EISRYQEMIQKLQNV L E S ERENCG L ----- VS 510
Cdd:pfam12128 384 - IKEQNN - R DIAGIKDK --- LAKIREARDRQ L AV AE DDLQA LE SELR E QLEAGKLEFNEEEYR L K S RLGELK L rlnqa TA 458
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 511 EQR L K LQ Q EN KQL R K E T eslrki A L E A Q KK A KVKISTMEH E FSIKERGFEVQLREMEDSN ------ RNSIV EL RH ----- 579
Cdd:pfam12128 459 TPE L L LQ L EN FDE R I E R ------ A R E E Q EA A NAEVERLQS E LRQARKRRDQASEALRQAS rrleer QSALD EL EL qlfpq 532
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 580 --- LL ATQQ K A A NR W KEETK K LTESAEIRINN L KS E LSRQKLHTQEL L SQLEMANEKVAEN E KLIL E HQ -- E KANRLQRR 654
Cdd:pfam12128 533 agt LL HFLR K E A PD W EQSIG K VISPELLHRTD L DP E VWDGSVGGELN L YGVKLDLKRIDVP E WAAS E EE lr E RLDKAEEA 612
410 420
....*....|....*....|....*
gi 16549896 655 L SQ A E E RA A S A SQ QL SVITVQRR KA 679
Cdd:pfam12128 613 L QS A R E KQ A A A EE QL VQANGELE KA 637
PRK03918
PRK03918 DNA double-strand break repair ATPase Rad50;
226-639
2.95e-03
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain]
Cd Length: 880
Bit Score: 40.82
E-value: 2.95e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 226 K K L RQAKL E LRVAVAKV E ELTNV TE DLQGQM K K KEK DVVSAHGREEASDRR L QQ L QSSIKQ LE IR --- L CVTIQ E ANQ L R 302
Cdd:PRK03918 165 K N L GEVIK E IKRRIERL E KFIKR TE NIEELI K E KEK ELEEVLREINEISSE L PE L REELEK LE KE vke L EELKE E IEE L E 244
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 303 T E NTH LE KQT R E L QA K CN ELE N --------- E RY E AI V RARNSMQLLE E ANLQK S QALL E EKQKEED IEK MKETVSR fv Q 373
Cdd:PRK03918 245 K E LES LE GSK R K L EE K IR ELE E rieelkkei E EL E EK V KELKELKEKA E EYIKL S EFYE E YLDELRE IEK RLSRLEE -- E 322
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 374 DAT I RTKKEVANT K KQ cni QISR L TEE L SA L QMECA E KQGQ i ERVIK E K KA VE EELE KIYREGR G NECD -- YRK LEE MHQ 451
Cdd:PRK03918 323 ING I EERIKELEE K EE --- RLEE L KKK L KE L EKRLE E LEER - HELYE E A KA KK EELE RLKKRLT G LTPE kl EKE LEE LEK 398
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 452 RFLVS E RSKDDLQL R LTRAENR IK Q L ETDSS E ei SRYQEMIQKLQNVLES E RENCG L VS E QRLK L QQEN K Q L RKET E SL R 531
Cdd:PRK03918 399 AKEEI E EEISKITA R IGELKKE IK E L KKAIE E -- LKKAKGKCPVCGRELT E EHRKE L LE E YTAE L KRIE K E L KEIE E KE R 476
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 532 K IAL E aqk KAKVKISTMEHEFS IK ERGFEV QL R E M E D snrnsiv E L RHLLATQQKAANRWK E ET K KLTESAEIR I NN LK S 611
Cdd:PRK03918 477 K LRK E --- LRELEKVLKKESEL IK LKELAE QL K E L E E ------- K L KKYNLEELEKKAEEY E KL K EKLIKLKGE I KS LK K 546
410 420
....*....|....*....|....*...
gi 16549896 612 EL SRQK lhtq EL LSQ L EMANE K VA E N E K 639
Cdd:PRK03918 547 EL EKLE ---- EL KKK L AELEK K LD E L E E 570
mukB
PRK04863 chromosome partition protein MukB;
321-679
3.06e-03
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain]
Cd Length: 1486
Bit Score: 41.10
E-value: 3.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 321 EL EN E R Y EAIVRARNSMQL L E E ANLQKSQALLE E KQK E E D IEKMKETVSR f VQ D A TIRTK K E vantk KQCNIQISR L T E E 400
Cdd:PRK04863 290 EL RR E L Y TSRRQLAAEQYR L V E MARELAELNEA E SDL E Q D YQAASDHLNL - VQ T A LRQQE K I ----- ERYQADLEE L E E R 363
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 401 L SALQMECA E KQG Q I E RVIKEKK A V EEE LEKI yreg RGNEC DY - RK L EEMHQ R FLVSERSKDD L Q lrltraen R I KQL ET 479
Cdd:PRK04863 364 L EEQNEVVE E ADE Q Q E ENEARAE A A EEE VDEL ---- KSQLA DY q QA L DVQQT R AIQYQQAVQA L E -------- R A KQL CG 431
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 480 DSSEEISRYQEMIQKL Q NV l E S E RENCG L VS EQ R L KLQ Q E - NK Q LRKETESL RKIA ----- L EA QKK A KVKISTMEHEFS 553
Cdd:PRK04863 432 LPDLTADNAEDWLEEF Q AK - E Q E ATEEL L SL EQ K L SVA Q A a HS Q FEQAYQLV RKIA gevsr S EA WDV A RELLRRLREQRH 510
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 554 IK E R -- GFEVQ L R E M E DSN R NS i VELRH LLA TQQ K AANR --- WKE E TKK L T E SA E I R INN L KSEL S RQKLHTQE L LS QLE 628
Cdd:PRK04863 511 LA E Q lq QLRMR L S E L E QRL R QQ - QRAER LLA EFC K RLGK nld DED E LEQ L Q E EL E A R LES L SESV S EARERRMA L RQ QLE 589
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 16549896 629 MANEKVAENEKLI --- L EH Q EKAN RL QRRLSQAE E RAASASQQLSVITVQR R KA 679
Cdd:PRK04863 590 QLQARIQRLAARA paw L AA Q DALA RL REQSGEEF E DSQDVTEYMQQLLERE R EL 643
PLN02939
PLN02939 transferase, transferring glycosyl groups
243-504
4.49e-03
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain]
Cd Length: 977
Bit Score: 40.27
E-value: 4.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 243 E E L TNVT - EDL Q G QMKKK EK DV ------- VS A HGRE E ASDRRLQQ LQ SS I KQ LE I RL CV T IQEANQLRT E NT H L E KQT re 314
Cdd:PLN02939 123 E Q L SDFQ l EDL V G MIQNA EK NI lllnqar LQ A LEDL E KILTEKEA LQ GK I NI LE M RL SE T DARIKLAAQ E KI H V E ILE -- 200
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 315 lqakc NE LE NE R Y E AIV R ARNSMQLLEEANLQKSQALL E EKQKEE DI EKM K ETVSRFVQ datir T KKE V ANTK K QCNIQI 394
Cdd:PLN02939 201 ----- EQ LE KL R N E LLI R GATEGLCVHSLSKELDVLKE E NMLLKD DI QFL K AELIEVAE ----- T EER V FKLE K ERSLLD 270
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 395 SR L T E ------------- E LS A LQ ME C A - EK QGQIERVIKEKKAVE E ELEKIYREGRGNECDYR KLE EMHQRFL VS ER S K 460
Cdd:PLN02939 271 AS L R E leskfivaqedvs K LS P LQ YD C W w EK VENLQDLLDRATNQV E KAALVLDQNQDLRDKVD KLE ASLKEAN VS KF S S 350
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 16549896 461 --- DD LQ LR L TRA E N R IKQLETDSSEE I SR YQE M I QKL Q NV L ESER E 504
Cdd:PLN02939 351 ykv EL LQ QK L KLL E E R LQASDHEIHSY I QL YQE S I KEF Q DT L SKLK E 397
EnvC
COG4942 Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
87-288
4.69e-03
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain]
Cd Length: 377
Bit Score: 39.75
E-value: 4.69e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 87 Q LE NVIK E NER L HS EL KDAVEKKLEAFPLGTEVGTD I Y A DDETV R N L QEQ L QLANQ E KTQAVELWQTVSQ EL DRLHKLYQ 166
Cdd:COG4942 28 E LE QLQQ E IAE L EK EL AALKKEEKALLKQLAALERR I A A LARRI R A L EQE L AALEA E LAELEKEIAELRA EL EAQKEELA 107
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 167 E HMTEAQIH vfe SQKQKDQ L F ---- DF QQLTKQ L HVTNENMEVTNQ Q f LKTVTEQSVIIEQ LR KK L RQAKL EL RVAV A KV 242
Cdd:COG4942 108 E LLRALYRL --- GRQPPLA L L lspe DF LDAVRR L QYLKYLAPARRE Q - AEELRADLAELAA LR AE L EAERA EL EALL A EL 183
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 16549896 243 EE LT nvt ED L QGQMKKKE K DVVSAHGREEASDRR L QQ LQ SSIKQ LE 288
Cdd:COG4942 184 EE ER --- AA L EALKAERQ K LLARLEKELAELAAE L AE LQ QEAEE LE 226
Smc
COG1196 Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
412-682
4.71e-03
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain]
Cd Length: 983
Bit Score: 40.31
E-value: 4.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 412 QG Q I E R V I -------------------- KE K K -------- A V EE E LE K --- I YR E GRGN ------ ECD ---- YR K L E E MH 450
Cdd:COG1196 143 QG M I D R I I eakpeerraiieeaagisky KE R K eeaerkle A T EE N LE R led I LG E LERQ lepler QAE kaer YR E L K E EL 222
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 451 QRFLVSERSK -- DD L QLR L TRA E NRIKQ LE TDSS E EISRYQ E miqklqnv LE S E R E ncglvs E Q RL K L QQENKQ L RKETE 528
Cdd:COG1196 223 KELEAELLLL kl RE L EAE L EEL E AELEE LE AELE E LEAELA E -------- LE A E L E ------ E L RL E L EELELE L EEAQA 288
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 529 SLRKIAL E AQKKAKVKISTM E hefsi KE R GF E VQ L R E M E DSNRNSIV EL RH L LATQQKAANRWK E ETKK L t E S AE IRINN 608
Cdd:COG1196 289 EEYELLA E LARLEQDIARLE E ----- RR R EL E ER L E E L E EELAELEE EL EE L EEELEELEEELE E AEEE L - E E AE AELAE 362
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 16549896 609 LKSE L SRQKLHTQ E LLSQ LE MAN E KVA E NEKLIL E HQEKANR L QRRLSQAE ER AASASQQ L SVITVQRRKAASL 682
Cdd:COG1196 363 AEEA L LEAEAELA E AEEE LE ELA E ELL E ALRAAA E LAAQLEE L EEAEEALL ER LERLEEE L EELEEALAELEEE 436
EnvC
COG4942 Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
393-639
5.68e-03
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain]
Cd Length: 377
Bit Score: 39.75
E-value: 5.68e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 393 QISRLTE EL SA LQ M E C AE KQGQIERVI KE K KA VEEE L EKIY R egrgnecdyr KLEEMHQ R FLVS E RSKDD L QLR L TRA E N 472
Cdd:COG4942 21 AAAEAEA EL EQ LQ Q E I AE LEKELAALK KE E KA LLKQ L AALE R ---------- RIAALAR R IRAL E QELAA L EAE L AEL E K 90
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 473 R I KQ L ETDSSEEISRYQ E MIQK L QNVLESERENCG L VS E QR L KLQQENKQ L RKETESL R KI A l E AQKKAKVKIS tmehef 552
Cdd:COG4942 91 E I AE L RAELEAQKEELA E LLRA L YRLGRQPPLALL L SP E DF L DAVRRLQY L KYLAPAR R EQ A - E ELRADLAELA ------ 163
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 553 sikergfev Q LR EMEDSN R NSIVE L RHL L ATQQK A ANRW K E E TK KL TESA E IRINN L KS EL SRQKLHTQ EL LSQLEMANE 632
Cdd:COG4942 164 --------- A LR AELEAE R AELEA L LAE L EEERA A LEAL K A E RQ KL LARL E KELAE L AA EL AELQQEAE EL EALIARLEA 234
....*..
gi 16549896 633 KV A ENEK 639
Cdd:COG4942 235 EA A AAAE 241
sbcc
TIGR00618 exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
133-669
6.14e-03
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain]
Cd Length: 1042
Bit Score: 39.95
E-value: 6.14e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 133 L QEQL QL ANQEKTQAVELWQTVS Q E L DRLH K LYQ E HMTEA Q IHVFESQKQKDQLFDFQQLTKQ L HVTNENM E v TNQQFLK 212
Cdd:TIGR00618 199 L TLRS QL LTLCTPCMPDTYHERK Q V L EKEL K HLR E ALQQT Q QSHAYLTQKREAQEEQLKKQQL L KQLRARI E - ELRAQEA 277
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 213 TVT E QSVI I EQL RK KLRQ A KLELR V AVAKVEELTNV TE d LQ GQ M KKKE K DV -- VS AH GREEA S DRRLQQ L QSSIKQL EI R 290
Cdd:TIGR00618 278 VLE E TQER I NRA RK AAPL A AHIKA V TQIEQQAQRIH TE - LQ SK M RSRA K LL mk RA AH VKQQS S IEEQRR L LQTLHSQ EI H 356
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 291 LC vti QEANQLRTENTHLEK Q TREL Q AKCNELENERYEAIVRARNSMQ L LEEANL Q KSQALLEEKQKEEDIEKMKETVSR 370
Cdd:TIGR00618 357 IR --- DAHEVATSIREISCQ Q HTLT Q HIHTLQQQKTTLTQKLQSLCKE L DILQRE Q ATIDTRTSAFRDLQGQLAHAKKQQ 433
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 371 FV Q DATIRTKKEVANTKK QC NIQISRLTE E LSALQM E CAEKQGQI E RVIKEKKAVEEELEKIYR E GRGNE C DYRKLEEMH 450
Cdd:TIGR00618 434 EL Q QRYAELCAAAITCTA QC EKLEKIHLQ E SAQSLK E REQQLQTK E QIHLQETRKKAVVLARLL E LQEEP C PLCGSCIHP 513
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 451 QRFLVSERSKDD L QL R LT R A E NRIK QLE ---------- T DSSEEISRYQ E MI Q KL Q NVLESERENCGLVS E QRLK LQ QEN 520
Cdd:TIGR00618 514 NPARQDIDNPGP L TR R MQ R G E QTYA QLE tseedvyhql T SERKQRASLK E QM Q EI Q QSFSILTQCDNRSK E DIPN LQ NIT 593
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16549896 521 KQ L RKE TE S L RKIALEAQKKAKVKISTMEH E FSIKERGFEV Q LREM E DSNRNSIVELRH L LA TQ QKAANRWKEETKKLT E 600
Cdd:TIGR00618 594 VR L QDL TE K L SEAEDMLACEQHALLRKLQP E QDLQDVRLHL Q QCSQ E LALKLTALHALQ L TL TQ ERVREHALSIRVLPK E 673
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 16549896 601 SAEI R INN L KSEL S RQKLH T QEL ------ LSQ L EMANEKVA E NEKLIL E HQEKANR L QRR L SQA E ERAASASQQ L 669
Cdd:TIGR00618 674 LLAS R QLA L QKMQ S EKEQL T YWK emlaqc QTL L RELETHIE E YDREFN E IENASSS L GSD L AAR E DALNQSLKE L 748
CYP51-like
cd11042 cytochrome P450 family 51 and similar cytochrome P450s; This family is composed of cytochrome ...
56-100
7.81e-03
cytochrome P450 family 51 and similar cytochrome P450s; This family is composed of cytochrome P450 51 (CYP51 or sterol 14alpha-demethylase) and related cytochrome P450s. CYP51 is the only cytochrome P450 enzyme with a conserved function across animals, fungi, and plants, in the synthesis of essential sterols. In mammals, it is expressed in many different tissues, with highest expression in testis, ovary, adrenal gland, prostate, liver, kidney, and lung. In fungi, CYP51 is a significant drug target for treatment of human protozoan infections. In plants, it functions within a specialized defense-related metabolic pathway. CYP51 is also found in several bacterial species. This family belongs to the large cytochrome P450 (P450, CYP) superfamily of heme-containing proteins that catalyze a variety of oxidative reactions of a large number of structurally different endogenous and exogenous compounds in organisms from all major domains of life. CYPs bind their diverse ligands in a buried, hydrophobic active site, which is accessed through a substrate access channel formed by two flexible helices and their connecting loop.
Pssm-ID: 410668 [Multi-domain]
Cd Length: 416
Bit Score: 39.12
E-value: 7.81e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 16549896 56 L AP L VT E YDKH LG ELNGQ L K Y yq KQVG EM K L q L ENV IKE NE RLH S 100
Cdd:cd11042 246 L EA L RE E QKEV LG DGDDP L T Y -- DVLK EM P L - L HAC IKE TL RLH P 287
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
