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Conserved domains on  [gi|189069183|dbj|BAG35521|]
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unnamed protein product [Homo sapiens]

Protein Classification

phosphoribosyl pyrophosphate synthase-associated protein( domain architecture ID 11226557)

phosphoribosyl pyrophosphate synthase-associated protein seems to play a negative regulatory role in 5-phosphoribose 1-diphosphate synthesis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Pribosyl_synth pfam14572
Phosphoribosyl synthetase-associated domain; This family includes several examples of enzymes ...
 167-350 7.57e-106

Phosphoribosyl synthetase-associated domain; This family includes several examples of enzymes from class EC:2.7.6.1, phosphoribosyl-pyrophosphate transferase.


:

Pssm-ID: 434046  Cd Length: 184  Bit Score: 308.28  E-value: 7.57e-106
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183  167 NYRNAVIVAKSPDAAKRAQSYAERLRLGLAVIHGEAQCTELDMDDGRHSPPMVKNATVHPGLELPLMMAKEKPPITVVGD 246
Cdd:pfam14572   1 DYRNAVIVARSPGSAKRATSFAERLRLGIAVIHGEQKEAESDEVDGRQSPPPYRSRTVSRSLGLPEIIPKEKPPMTVVGD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183  247 VGGRIAIIVDDIIDDVESFVAAAEILKERGAYKIYVMATHGILSAEAPRLIEESSVDEVVVTNTVPHEVQKLQCPKIKTV 326
Cdd:pfam14572  81 VGGRIAIIVDDMIDDVDSFVAAAELLKERGAYKIYVMATHGLLSSDAPRLLEASPIDEVVVTNTIPHEIQKMQCHKIKTI 160

                         170       180
                  ....*....|....*....|....
gi 189069183  327 DISLILSEAIRRIHNGESMAYLFR 350
Cdd:pfam14572 161 DISQLIAEAIRRIHNGESMSYLFR 184
Pribosyltran_N pfam13793
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found ...
 9-126 7.61e-49

N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found N-terminal to the Pribosyltran, pfam00156.


:

Pssm-ID: 433483 [Multi-domain]  Cd Length: 117  Bit Score: 159.89  E-value: 7.61e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183    9 RVFSANStaaCTELAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTAC 88
Cdd:pfam13793   2 KIFSGNS---NPELAEKIAKRLGIPLGKATVSRFSDGEIYVRIEESVRGKDVFIIQSTCPPVNDNLMELLIMIDALKRAS 78

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 189069183   89 ARNIIGVIPYFPYSKQSKM-RKRGSIVCKLLASMLAKAG 126
Cdd:pfam13793  79 AKRITAVIPYFGYARQDRKdKPREPITAKLVADLLEAAG 117
 
Name Accession Description Interval E-value
Pribosyl_synth pfam14572
Phosphoribosyl synthetase-associated domain; This family includes several examples of enzymes ...
 167-350 7.57e-106

Phosphoribosyl synthetase-associated domain; This family includes several examples of enzymes from class EC:2.7.6.1, phosphoribosyl-pyrophosphate transferase.


Pssm-ID: 434046  Cd Length: 184  Bit Score: 308.28  E-value: 7.57e-106
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183  167 NYRNAVIVAKSPDAAKRAQSYAERLRLGLAVIHGEAQCTELDMDDGRHSPPMVKNATVHPGLELPLMMAKEKPPITVVGD 246
Cdd:pfam14572   1 DYRNAVIVARSPGSAKRATSFAERLRLGIAVIHGEQKEAESDEVDGRQSPPPYRSRTVSRSLGLPEIIPKEKPPMTVVGD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183  247 VGGRIAIIVDDIIDDVESFVAAAEILKERGAYKIYVMATHGILSAEAPRLIEESSVDEVVVTNTVPHEVQKLQCPKIKTV 326
Cdd:pfam14572  81 VGGRIAIIVDDMIDDVDSFVAAAELLKERGAYKIYVMATHGLLSSDAPRLLEASPIDEVVVTNTIPHEIQKMQCHKIKTI 160

                         170       180
                  ....*....|....*....|....
gi 189069183  327 DISLILSEAIRRIHNGESMAYLFR 350
Cdd:pfam14572 161 DISQLIAEAIRRIHNGESMSYLFR 184
PrsA COG0462
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; ...
 9-350 9.37e-99

Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; Phosphoribosylpyrophosphate synthetase is part of the Pathway/BioSystem: Histidine biosynthesis, Purine biosynthesis


Pssm-ID: 440230 [Multi-domain]  Cd Length: 311  Bit Score: 294.66  E-value: 9.37e-99
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183   9 RVFSANSTAactELAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTAC 88
Cdd:COG0462    5 KIFSGNANP---ELAEEIAEYLGVPLGKAEVRRFSDGEIYVRIEESVRGRDVFVIQSTSPPVNDNLMELLIMIDALKRAS 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183  89 ARNIIGVIPYFPYSKQ-SKMRKRGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFSFPVDNLRASPFLLQYIQEEipN 167
Cdd:COG0462   82 ARRITAVIPYYGYARQdRKFRPREPITAKLVADLLEAAGADRVLTVDLHAPQIQGFFDIPVDHLYAAPLLADYIKSK--D 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183 168 YRNAVIVakSPDA--AKRAQSYAERLRLGLAVIHGEaqcteldmddgRHSPpmvKNATVHpglelplmmakekppiTVVG 245
Cdd:COG0462  160 LEDLVVV--SPDVggVKRARAFAKRLGAPLAIIDKR-----------RPGA---NEVEVM----------------NIIG 207

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183 246 DVGGRI----------AiivddiiddvESFVAAAEILKERGAYKIYVMATHGILSAEAPRLIEESSVDEVVVTNTVPHEV 315
Cdd:COG0462  208 DVEGKTciivddmidtG----------GTLVEAAEALKEAGAKSVYAAATHGVLSGPAVERLENSPIDELVVTDTIPLPE 277

                        330       340       350
                 ....*....|....*....|....*....|....*
gi 189069183 316 QKlQCPKIKTVDISLILSEAIRRIHNGESMAYLFR 350
Cdd:COG0462  278 EK-RCDKIKVLSVAPLLAEAIRRIHEGESVSSLFD 311
PRK01259 PRK01259
ribose-phosphate diphosphokinase;
8-350 2.81e-90

ribose-phosphate diphosphokinase;


Pssm-ID: 234929 [Multi-domain]  Cd Length: 309  Bit Score: 273.15  E-value: 2.81e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183   8 YRVFSANStaaCTELAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTA 87
Cdd:PRK01259   1 MKLFAGNA---NPELAEKIAKYLGIPLGKASVGRFSDGEISVEINENVRGKDVFIIQSTCAPTNDNLMELLIMIDALKRA 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183  88 CARNIIGVIPYFPYSKQS-KMRKRGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFSFPVDNLRASPFLLQYIQEEip 166
Cdd:PRK01259  78 SAGRITAVIPYFGYARQDrKARSRVPITAKLVANLLETAGADRVLTMDLHADQIQGFFDIPVDNLYGSPILLEDIKQK-- 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183 167 NYRNAVIVakSPD--AAKRAQSYAERLRLGLAVIhgeaqcteldmdDGRHSPPMVknATVhpglelplmmakekppITVV 244
Cdd:PRK01259 156 NLENLVVV--SPDvgGVVRARALAKRLDADLAII------------DKRRPRANV--SEV----------------MNII 203

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183 245 GDVGGRIAIIVDDIIDDVESFVAAAEILKERGAYKIYVMATHGILSAEAPRLIEESSVDEVVVTNTVPHEVQKLQCPKIK 324
Cdd:PRK01259 204 GDVEGRDCILVDDMIDTAGTLCKAAEALKERGAKSVYAYATHPVLSGGAIERIENSVIDELVVTDSIPLSEEAKKCDKIR 283

                        330       340
                 ....*....|....*....|....*.
gi 189069183 325 TVDISLILSEAIRRIHNGESMAYLFR 350
Cdd:PRK01259 284 VLSVAPLLAEAIRRISNEESVSSLFD 309
ribP_PPkin TIGR01251
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In ...
 8-350 2.43e-88

ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In some systems, close homologs lacking enzymatic activity exist and perform regulatory functions. The model is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]


Pssm-ID: 273523 [Multi-domain]  Cd Length: 308  Bit Score: 267.99  E-value: 2.43e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183    8 YRVFSANSTAactELAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFII-QTIPRDVNTAVMELLIMAYALKT 86
Cdd:TIGR01251   1 MKIFSGSSNQ---ELAQKVAKNLGLPLGDVEVKRFPDGELYVRINESVRGKDVFIIqQSTSAPVNDNLMELLIMIDALKR 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183   87 ACARNIIGVIPYFPYSKQSKMRKRG-SIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFSFPVDNLRASPFLLQYIQEEI 165
Cdd:TIGR01251  78 ASAKSITAVIPYYGYARQDKKFKSRePISAKLVANLLETAGADRVLTVDLHSPQIQGFFDVPVDNLYASPVLAEYLKKKI 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183  166 PNyrNAVIVakSPD--AAKRAQSYAERLRLGLAVIHGEaqcteldmddgRHSPPmvKNATVHPglelplmmakekppitV 243
Cdd:TIGR01251 158 LD--NPVVV--SPDagGVERAKKVADALGCPLAIIDKR-----------RISAT--NEVEVMN----------------L 204

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183  244 VGDVGGRIAIIVDDIIDDVESFVAAAEILKERGAYKIYVMATHGILSAEAPRLIEESSVDEVVVTNTVPHEVqklQCPKI 323
Cdd:TIGR01251 205 VGDVEGKDVVIVDDIIDTGGTIAKAAEILKSAGAKRVIAAATHGVFSGPAIERIANAGVEEVIVTNTIPHEK---HKPKV 281

                         330       340
                  ....*....|....*....|....*..
gi 189069183  324 KTVDISLILSEAIRRIHNGESMAYLFR 350
Cdd:TIGR01251 282 SVISVAPLIAEAIRRIHNNESVSSLFD 308
Pribosyltran_N pfam13793
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found ...
 9-126 7.61e-49

N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found N-terminal to the Pribosyltran, pfam00156.


Pssm-ID: 433483 [Multi-domain]  Cd Length: 117  Bit Score: 159.89  E-value: 7.61e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183    9 RVFSANStaaCTELAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTAC 88
Cdd:pfam13793   2 KIFSGNS---NPELAEKIAKRLGIPLGKATVSRFSDGEIYVRIEESVRGKDVFIIQSTCPPVNDNLMELLIMIDALKRAS 78

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 189069183   89 ARNIIGVIPYFPYSKQSKM-RKRGSIVCKLLASMLAKAG 126
Cdd:pfam13793  79 AKRITAVIPYFGYARQDRKdKPREPITAKLVADLLEAAG 117
 
Name Accession Description Interval E-value
Pribosyl_synth pfam14572
Phosphoribosyl synthetase-associated domain; This family includes several examples of enzymes ...
 167-350 7.57e-106

Phosphoribosyl synthetase-associated domain; This family includes several examples of enzymes from class EC:2.7.6.1, phosphoribosyl-pyrophosphate transferase.


Pssm-ID: 434046  Cd Length: 184  Bit Score: 308.28  E-value: 7.57e-106
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183  167 NYRNAVIVAKSPDAAKRAQSYAERLRLGLAVIHGEAQCTELDMDDGRHSPPMVKNATVHPGLELPLMMAKEKPPITVVGD 246
Cdd:pfam14572   1 DYRNAVIVARSPGSAKRATSFAERLRLGIAVIHGEQKEAESDEVDGRQSPPPYRSRTVSRSLGLPEIIPKEKPPMTVVGD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183  247 VGGRIAIIVDDIIDDVESFVAAAEILKERGAYKIYVMATHGILSAEAPRLIEESSVDEVVVTNTVPHEVQKLQCPKIKTV 326
Cdd:pfam14572  81 VGGRIAIIVDDMIDDVDSFVAAAELLKERGAYKIYVMATHGLLSSDAPRLLEASPIDEVVVTNTIPHEIQKMQCHKIKTI 160

                         170       180
                  ....*....|....*....|....
gi 189069183  327 DISLILSEAIRRIHNGESMAYLFR 350
Cdd:pfam14572 161 DISQLIAEAIRRIHNGESMSYLFR 184
PrsA COG0462
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; ...
 9-350 9.37e-99

Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; Phosphoribosylpyrophosphate synthetase is part of the Pathway/BioSystem: Histidine biosynthesis, Purine biosynthesis


Pssm-ID: 440230 [Multi-domain]  Cd Length: 311  Bit Score: 294.66  E-value: 9.37e-99
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183   9 RVFSANSTAactELAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTAC 88
Cdd:COG0462    5 KIFSGNANP---ELAEEIAEYLGVPLGKAEVRRFSDGEIYVRIEESVRGRDVFVIQSTSPPVNDNLMELLIMIDALKRAS 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183  89 ARNIIGVIPYFPYSKQ-SKMRKRGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFSFPVDNLRASPFLLQYIQEEipN 167
Cdd:COG0462   82 ARRITAVIPYYGYARQdRKFRPREPITAKLVADLLEAAGADRVLTVDLHAPQIQGFFDIPVDHLYAAPLLADYIKSK--D 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183 168 YRNAVIVakSPDA--AKRAQSYAERLRLGLAVIHGEaqcteldmddgRHSPpmvKNATVHpglelplmmakekppiTVVG 245
Cdd:COG0462  160 LEDLVVV--SPDVggVKRARAFAKRLGAPLAIIDKR-----------RPGA---NEVEVM----------------NIIG 207

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183 246 DVGGRI----------AiivddiiddvESFVAAAEILKERGAYKIYVMATHGILSAEAPRLIEESSVDEVVVTNTVPHEV 315
Cdd:COG0462  208 DVEGKTciivddmidtG----------GTLVEAAEALKEAGAKSVYAAATHGVLSGPAVERLENSPIDELVVTDTIPLPE 277

                        330       340       350
                 ....*....|....*....|....*....|....*
gi 189069183 316 QKlQCPKIKTVDISLILSEAIRRIHNGESMAYLFR 350
Cdd:COG0462  278 EK-RCDKIKVLSVAPLLAEAIRRIHEGESVSSLFD 311
PRK01259 PRK01259
ribose-phosphate diphosphokinase;
8-350 2.81e-90

ribose-phosphate diphosphokinase;


Pssm-ID: 234929 [Multi-domain]  Cd Length: 309  Bit Score: 273.15  E-value: 2.81e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183   8 YRVFSANStaaCTELAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTA 87
Cdd:PRK01259   1 MKLFAGNA---NPELAEKIAKYLGIPLGKASVGRFSDGEISVEINENVRGKDVFIIQSTCAPTNDNLMELLIMIDALKRA 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183  88 CARNIIGVIPYFPYSKQS-KMRKRGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFSFPVDNLRASPFLLQYIQEEip 166
Cdd:PRK01259  78 SAGRITAVIPYFGYARQDrKARSRVPITAKLVANLLETAGADRVLTMDLHADQIQGFFDIPVDNLYGSPILLEDIKQK-- 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183 167 NYRNAVIVakSPD--AAKRAQSYAERLRLGLAVIhgeaqcteldmdDGRHSPPMVknATVhpglelplmmakekppITVV 244
Cdd:PRK01259 156 NLENLVVV--SPDvgGVVRARALAKRLDADLAII------------DKRRPRANV--SEV----------------MNII 203

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183 245 GDVGGRIAIIVDDIIDDVESFVAAAEILKERGAYKIYVMATHGILSAEAPRLIEESSVDEVVVTNTVPHEVQKLQCPKIK 324
Cdd:PRK01259 204 GDVEGRDCILVDDMIDTAGTLCKAAEALKERGAKSVYAYATHPVLSGGAIERIENSVIDELVVTDSIPLSEEAKKCDKIR 283

                        330       340
                 ....*....|....*....|....*.
gi 189069183 325 TVDISLILSEAIRRIHNGESMAYLFR 350
Cdd:PRK01259 284 VLSVAPLLAEAIRRISNEESVSSLFD 309
ribP_PPkin TIGR01251
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In ...
 8-350 2.43e-88

ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In some systems, close homologs lacking enzymatic activity exist and perform regulatory functions. The model is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]


Pssm-ID: 273523 [Multi-domain]  Cd Length: 308  Bit Score: 267.99  E-value: 2.43e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183    8 YRVFSANSTAactELAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFII-QTIPRDVNTAVMELLIMAYALKT 86
Cdd:TIGR01251   1 MKIFSGSSNQ---ELAQKVAKNLGLPLGDVEVKRFPDGELYVRINESVRGKDVFIIqQSTSAPVNDNLMELLIMIDALKR 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183   87 ACARNIIGVIPYFPYSKQSKMRKRG-SIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFSFPVDNLRASPFLLQYIQEEI 165
Cdd:TIGR01251  78 ASAKSITAVIPYYGYARQDKKFKSRePISAKLVANLLETAGADRVLTVDLHSPQIQGFFDVPVDNLYASPVLAEYLKKKI 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183  166 PNyrNAVIVakSPD--AAKRAQSYAERLRLGLAVIHGEaqcteldmddgRHSPPmvKNATVHPglelplmmakekppitV 243
Cdd:TIGR01251 158 LD--NPVVV--SPDagGVERAKKVADALGCPLAIIDKR-----------RISAT--NEVEVMN----------------L 204

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183  244 VGDVGGRIAIIVDDIIDDVESFVAAAEILKERGAYKIYVMATHGILSAEAPRLIEESSVDEVVVTNTVPHEVqklQCPKI 323
Cdd:TIGR01251 205 VGDVEGKDVVIVDDIIDTGGTIAKAAEILKSAGAKRVIAAATHGVFSGPAIERIANAGVEEVIVTNTIPHEK---HKPKV 281

                         330       340
                  ....*....|....*....|....*..
gi 189069183  324 KTVDISLILSEAIRRIHNGESMAYLFR 350
Cdd:TIGR01251 282 SVISVAPLIAEAIRRIHNNESVSSLFD 308
PRK03092 PRK03092
ribose-phosphate diphosphokinase;
22-349 8.21e-67

ribose-phosphate diphosphokinase;


Pssm-ID: 179535 [Multi-domain]  Cd Length: 304  Bit Score: 212.89  E-value: 8.21e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183  22 LAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTACARNIIGVIPYFPY 101
Cdd:PRK03092   1 LAEEVAKELGVEVTPTTAYDFANGEIYVRFEESVRGCDAFVLQSHTAPINKWLMEQLIMIDALKRASAKRITVVLPFYPY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183 102 SKQSKM-RKRGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFSFPVDNLRASPFLLQYIQEEIPNyRNAVIVakSPDA 180
Cdd:PRK03092  81 ARQDKKhRGREPISARLVADLFKTAGADRIMTVDLHTAQIQGFFDGPVDHLFAMPLLADYVRDKYDL-DNVTVV--SPDA 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183 181 A--KRAQSYAERL-RLGLAVIHgeaqcteldmddGRHSPPMVKNATVHpglelplmmakekppiTVVGDVGGRIAIIVDD 257
Cdd:PRK03092 158 GrvRVAEQWADRLgGAPLAFIH------------KTRDPTVPNQVVAN----------------RVVGDVEGRTCVLVDD 209

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183 258 IIDDVESFVAAAEILKERGAYKIYVMATHGILSAEAPRLIEESSVDEVVVTNTVPHEVQKlQCPKIKTVDISLILSEAIR 337
Cdd:PRK03092 210 MIDTGGTIAGAVRALKEAGAKDVIIAATHGVLSGPAAERLKNCGAREVVVTDTLPIPEEK-RFDKLTVLSIAPLLARAIR 288

                        330
                 ....*....|..
gi 189069183 338 RIHNGESMAYLF 349
Cdd:PRK03092 289 EVFEDGSVTSLF 300
PLN02369 PLN02369
ribose-phosphate pyrophosphokinase
 21-350 1.09e-65

ribose-phosphate pyrophosphokinase


Pssm-ID: 215209 [Multi-domain]  Cd Length: 302  Bit Score: 209.94  E-value: 1.09e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183  21 ELAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTACARNIIGVIPYFP 100
Cdd:PLN02369   2 ALSQEIACYLGLELGKITIKRFADGEIYVQLQESVRGCDVFLVQPTCPPANENLMELLIMIDACRRASAKRITAVIPYFG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183 101 YSKQS-KMRKRGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFSFPVDNLRASPFLLQYIQEEIPNYRNAVIVakSPD 179
Cdd:PLN02369  82 YARADrKTQGRESIAAKLVANLITEAGADRVLACDLHSGQSMGYFDIPVDHVYGQPVILDYLASKTISSPDLVVV--SPD 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183 180 AAK--RAQSYAERLR-LGLAVIhgeaqcteldmDDGRHSPPMVKnatvhpglelplmmakekpPITVVGDVGGRIAIIVD 256
Cdd:PLN02369 160 VGGvaRARAFAKKLSdAPLAIV-----------DKRRQGHNVAE-------------------VMNLIGDVKGKVAIMVD 209

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183 257 DIIDDVESFVAAAEILKERGAYKIYVMATHGILSAEAPRLIEESSVDEVVVTNTVPHEVQKlQCPKIKTVDISLILSEAI 336
Cdd:PLN02369 210 DMIDTAGTITKGAALLHQEGAREVYACATHAVFSPPAIERLSSGLFQEVIVTNTIPVSEKN-YFPQLTVLSVANLLGETI 288

                        330
                 ....*....|....
gi 189069183 337 RRIHNGESMAYLFR 350
Cdd:PLN02369 289 WRVHDDCSVSSIFD 302
PRK04923 PRK04923
ribose-phosphate diphosphokinase;
10-349 1.10e-65

ribose-phosphate diphosphokinase;


Pssm-ID: 179893 [Multi-domain]  Cd Length: 319  Bit Score: 210.56  E-value: 1.10e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183  10 VFSANstaACTELAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTACA 89
Cdd:PRK04923   9 VFSGN---ANKPLAQSICKELGVRMGKALVTRFSDGEVQVEIEESVRRQEVFVIQPTCAPSAENLMELLVLIDALKRASA 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183  90 RNIIGVIPYFPYSKQSK-MRK-RGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFSFPVDNLRASPFLLQYIQEEIpN 167
Cdd:PRK04923  86 ASVTAVIPYFGYSRQDRrMRSsRVPITAKVAAKMISAMGADRVLTVDLHADQIQGFFDVPVDNVYASPLLLADIWRAY-G 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183 168 YRNAVIVAKSPDAAKRAQSYAERL-RLGLAVIhgeaqcteldmdDGRHspPMVKNATVhpglelplmmakekppITVVGD 246
Cdd:PRK04923 165 TDNLIVVSPDVGGVVRARAVAKRLdDADLAII------------DKRR--PRANVATV----------------MNIIGD 214

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183 247 VGGRIAIIVDDIIDDVESFVAAAEILKERGAYKIYVMATHGILSAEAPRLIEESSVDEVVVTNTVPHEVQKLQCPKIKTV 326
Cdd:PRK04923 215 VQGKTCVLVDDLVDTAGTLCAAAAALKQRGALKVVAYITHPVLSGPAVDNINNSQLDELVVTDTIPLSEAARACAKIRQL 294

                        330       340
                 ....*....|....*....|...
gi 189069183 327 DISLILSEAIRRIHNGESMAYLF 349
Cdd:PRK04923 295 SVAELLAETIRRIAFGESVSSLY 317
PRK02269 PRK02269
ribose-phosphate diphosphokinase;
9-349 1.25e-65

ribose-phosphate diphosphokinase;


Pssm-ID: 167353 [Multi-domain]  Cd Length: 320  Bit Score: 210.42  E-value: 1.25e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183   9 RVFSANSTaacTELAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTAC 88
Cdd:PRK02269   7 KLFALSSN---KELAEKVAQEIGIELGKSSVRQFSDGEIQVNIEESIRGHHVFILQSTSSPVNDNLMEILIMVDALKRAS 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183  89 ARNIIGVIPYFPYSKQS-KMRKRGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFSFPVDNLRASPFLLQYIQEEIPN 167
Cdd:PRK02269  84 AESINVVMPYYGYARQDrKARSREPITSKLVANMLEVAGVDRLLTVDLHAAQIQGFFDIPVDHLMGAPLIADYFDRRGLV 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183 168 YRNAVIVakSPDAA--KRAQSYAERLRLGLAVIhgeaqcteldmdDGRHSPPMVKNATVhpglelplmmakekppITVVG 245
Cdd:PRK02269 164 GDDVVVV--SPDHGgvTRARKLAQFLKTPIAII------------DKRRSVDKMNTSEV----------------MNIIG 213

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183 246 DVGGRIAIIVDDIIDDVESFVAAAEILKERGAYKIYVMATHGILSAEAPRLIEESSVDEVVVTNTVPHEVQKLqCPKIKT 325
Cdd:PRK02269 214 NVKGKKCILIDDMIDTAGTICHAADALAEAGATEVYASCTHPVLSGPALDNIQKSAIEKLVVLDTIYLPEERL-IDKIEQ 292

                        330       340
                 ....*....|....*....|....
gi 189069183 326 VDISLILSEAIRRIHNGESMAYLF 349
Cdd:PRK02269 293 ISIADLLGEAIIRIHEKRPLSPLF 316
PRK02458 PRK02458
ribose-phosphate pyrophosphokinase; Provisional
 1-350 2.28e-60

ribose-phosphate pyrophosphokinase; Provisional


Pssm-ID: 235039 [Multi-domain]  Cd Length: 323  Bit Score: 196.88  E-value: 2.28e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183   1 MNAARTGYRVFSANSTaacTELAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIM 80
Cdd:PRK02458   3 ERYADKQIKLFSLNSN---LEIAEKIAQAAGVPLGKLSSRQFSDGEIMINIEESVRGDDIYIIQSTSFPVNDHLWELLIM 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183  81 AYALKTACARNIIGVIPYFPYSKQSKMRK-RGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFSFPVDNLRASPFLLQ 159
Cdd:PRK02458  80 IDACKRASANTVNVVLPYFGYARQDRIAKpREPITAKLVANMLVKAGVDRVLTLDLHAVQVQGFFDIPVDNLFTVPLFAK 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183 160 YIQEEIPNYRNAVIVAKSPDAAKRAQSYAERLRLGLAVIhgeaqctELDMDDGrhsppmvknatvhpglelplmmakEKP 239
Cdd:PRK02458 160 HYCKKGLSGSDVVVVSPKNSGIKRARSLAEYLDAPIAII-------DYAQDDS------------------------ERE 208

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183 240 PITVVGDVGGRIAIIVDDIIDDVESFVAAAEILKERGAYKIYVMATHGILSAEAPRLIEESSVDEVVVTNTVpheVQKLQ 319
Cdd:PRK02458 209 EGYIIGDVAGKKAILIDDILNTGKTFAEAAKIVEREGATEIYAVASHGLFAGGAAEVLENAPIKEILVTDSV---ATKER 285

                        330       340       350
                 ....*....|....*....|....*....|..
gi 189069183 320 CPK-IKTVDISLILSEAIRRIHNGESMAYLFR 350
Cdd:PRK02458 286 VPKnVTYLSASELIADAIIRIHERKPLSPLFA 317
PRK02812 PRK02812
ribose-phosphate pyrophosphokinase; Provisional
 9-350 8.79e-57

ribose-phosphate pyrophosphokinase; Provisional


Pssm-ID: 235072 [Multi-domain]  Cd Length: 330  Bit Score: 187.64  E-value: 8.79e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183   9 RVFSANSTAActeLAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTAC 88
Cdd:PRK02812  23 RLFSGSSNPA---LAQEVARYLGMDLGPMIRKRFADGELYVQIQESIRGCDVYLIQPTCAPVNDHLMELLIMVDACRRAS 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183  89 ARNIIGVIPYFPYSKQS-KMRKRGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFSFPVDNLRASPFLLQYIQEEipN 167
Cdd:PRK02812 100 ARQITAVIPYYGYARADrKTAGRESITAKLVANLITKAGADRVLAMDLHSAQIQGYFDIPCDHVYGSPVLLDYLASK--N 177

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183 168 YRNAVIVakSPD--AAKRAQSYAERLRLG-LAVIhgeaqcteldmdDGRHSPPMVKNAtvhpglelplmmakekppITVV 244
Cdd:PRK02812 178 LEDIVVV--SPDvgGVARARAFAKKLNDApLAII------------DKRRQAHNVAEV------------------LNVI 225

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183 245 GDVGGRIAIIVDDIIDDVESFVAAAEILKERGAYKIYVMATHGILSAEAPRLIEESSVDEVVVTNTVPHEvQKLQCPKIK 324
Cdd:PRK02812 226 GDVKGKTAILVDDMIDTGGTICEGARLLRKEGAKQVYACATHAVFSPPAIERLSSGLFEEVIVTNTIPVP-EERRFPQLK 304

                        330       340
                 ....*....|....*....|....*.
gi 189069183 325 TVDISLILSEAIRRIHNGESMAYLFR 350
Cdd:PRK02812 305 VLSVANMLGEAIWRIHEESSVSSMFR 330
PTZ00145 PTZ00145
phosphoribosylpyrophosphate synthetase; Provisional
 10-349 1.01e-52

phosphoribosylpyrophosphate synthetase; Provisional


Pssm-ID: 240290 [Multi-domain]  Cd Length: 439  Bit Score: 180.07  E-value: 1.01e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183  10 VFSANSTAActeLAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTACA 89
Cdd:PTZ00145 122 LFSGSSNPL---LSKNIADHLGTILGRVHLKRFADGEVSMQFLESIRGKDVYIIQPTCPPVNENLIELLLMISTCRRASA 198

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183  90 RNIIGVIPYFPYSKQS-KMRKRGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFS--FPVDNLRASPFLLQYIQEEiP 166
Cdd:PTZ00145 199 KKITAVIPYYGYARQDrKLSSRVPISAADVARMIEAMGVDRVVAIDLHSGQIQGFFGprVPVDNLEAQLIGLDYFTKK-D 277

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183 167 NYRnAVIVakSPDAAK--RAQSYAERLrlglaVIHGEAQCTeLDMddgrhsppMVKNATvhpglelplmMAKEKPPITVV 244
Cdd:PTZ00145 278 LYK-PVIV--SPDAGGvyRARKFQDGL-----NHRGISDCG-IAM--------LIKQRT----------KPNEIEKMDLV 330

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183 245 GDVGGRIAIIVDDIIDDVESFVAAAEILKERGAYKIYVMATHGILSAEAPRLIEESSVDEVVVTNTVPHEVQKLQCPKIK 324
Cdd:PTZ00145 331 GNVYDSDVIIVDDMIDTSGTLCEAAKQLKKHGARRVFAFATHGLFSGPAIERIEASPLEEVVVTDTVKSNKNIDSCKKIT 410

                        330       340
                 ....*....|....*....|....*
gi 189069183 325 TVDISLILSEAIRRIHNGESMAYLF 349
Cdd:PTZ00145 411 KLSVSVLVADAIRRIHQKESLNDLF 435
PRK00553 PRK00553
ribose-phosphate pyrophosphokinase; Provisional
 1-349 2.14e-51

ribose-phosphate pyrophosphokinase; Provisional


Pssm-ID: 179062 [Multi-domain]  Cd Length: 332  Bit Score: 173.95  E-value: 2.14e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183   1 MNAARTGYRVFSANSTaacTELAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIM 80
Cdd:PRK00553   3 LSIDKSNHVIFSLSKA---KKLVDSICRKLSMKPGEIVIQKFADGETYIRFDESVRNKDVVIFQSTCSPVNDSLMELLIA 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183  81 AYALKTACARNIIGVIPYFPYSKQS-KMRKRGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFSFPVDNLRASPFLLQ 159
Cdd:PRK00553  80 IDALKRGSAKSITAILPYYGYARQDrKTAGREPITSKLVADLLTKAGVTRVTLTDIHSDQTQGFFDIPVDILRTYHVFLS 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183 160 YIQEEIpNYRNAVIVakSPD--AAKRAQSYAERLRLGLAVIhgeaqcteldmdDGRHSPPMVKNAtvhpglelplmmake 237
Cdd:PRK00553 160 RVLELL-GKKDLVVV--SPDygGVKRARLIAESLELPLAII------------DKRRPKHNVAES--------------- 209

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183 238 kppITVVGDVGGRIAIIVDDIIDDVESFVAAAEILKERGAYKIYVMATHGILSAEAPRLIEES----SVDEVVVTNTVPH 313
Cdd:PRK00553 210 ---INVLGEVKNKNCLIVDDMIDTGGTVIAAAKLLKKQKAKKVCVMATHGLFNKNAIQLFDEAfkkkLIDKLFVSNSIPQ 286

                        330       340       350
                 ....*....|....*....|....*....|....*.
gi 189069183 314 EVQKlQCPKIKTVDISLILSEAIRRIHNGESMAYLF 349
Cdd:PRK00553 287 TKFE-KKPQFKVVDLAHLYEEVLLCYANGGSISAIY 321
Pribosyltran_N pfam13793
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found ...
 9-126 7.61e-49

N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found N-terminal to the Pribosyltran, pfam00156.


Pssm-ID: 433483 [Multi-domain]  Cd Length: 117  Bit Score: 159.89  E-value: 7.61e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183    9 RVFSANStaaCTELAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTAC 88
Cdd:pfam13793   2 KIFSGNS---NPELAEKIAKRLGIPLGKATVSRFSDGEIYVRIEESVRGKDVFIIQSTCPPVNDNLMELLIMIDALKRAS 78

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 189069183   89 ARNIIGVIPYFPYSKQSKM-RKRGSIVCKLLASMLAKAG 126
Cdd:pfam13793  79 AKRITAVIPYFGYARQDRKdKPREPITAKLVADLLEAAG 117
PRK00934 PRK00934
ribose-phosphate pyrophosphokinase; Provisional
 22-318 1.26e-37

ribose-phosphate pyrophosphokinase; Provisional


Pssm-ID: 234868 [Multi-domain]  Cd Length: 285  Bit Score: 136.20  E-value: 1.26e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183  22 LAKRITERLGAELgksvVYQETN----GETRVEIKESVRGQDIFIIQTIPRDvNTAVMELLIMAYALKTACARNIIGVIP 97
Cdd:PRK00934  11 LASEVARLLNTEL----ALVETKrfpdGELYVRILGEIDGEDVVIISTTYPQ-DENLVELLLLIDALRDEGAKSITLVIP 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183  98 YFPYSKQSKMRKRG-SIVCKLLASMLAKAGlTHIITMDLHQKEIQGFFSFPVDNLRASPFLLQYIQEEIpnyRNAVIVAk 176
Cdd:PRK00934  86 YLGYARQDKRFKPGePISARAIAKIISAYY-DRIITINIHEPSILEFFPIPFINLDAAPLIAEYIGDKL---DDPLVLA- 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183 177 sPD--AAKRAQSYAERLrlGLAVIHGEAQcteldmddgRHSPPMVKNATVHpglelplMMAKEKPpITVVGDV---GGRI 251
Cdd:PRK00934 161 -PDkgALELAKEAAEIL--GCEYDYLEKT---------RISPTEVEIAPKN-------LDVKGKD-VLIVDDIistGGTM 220

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 189069183 252 AIivddiiddvesfvaAAEILKERGAYKIYVMATHGILSAEAPRLIEESSVDEVVVTNTVPHEVQKL 318
Cdd:PRK00934 221 AT--------------AIKILKEQGAKKVYVACVHPVLVGDAILKLYNAGVDEIIVTDTLESEVSKI 273
PRK06827 PRK06827
phosphoribosylpyrophosphate synthetase; Provisional
 44-351 3.54e-30

phosphoribosylpyrophosphate synthetase; Provisional


Pssm-ID: 180714 [Multi-domain]  Cd Length: 382  Bit Score: 118.52  E-value: 3.54e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183  44 NGETRVEIKESVRGQDIFIIQ--------------TIPRDVNTAVMEL--LIMAYALKtacARNIIGVIPYFPYSKQSKM 107
Cdd:PRK06827  64 NGEAKGEILESVRGKDIYILQdvgnysvtynmfgeKNHMSPDDHFQDLkrTIDAIRGK---ARRITVIMPFLYESRQHKR 140

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183 108 RKRGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGffSFPV---DNLRASPFLLQYIQEEIPNYR----NAVIVakSPD- 179
Cdd:PRK06827 141 KGRESLDCALALQELEELGVDNIITFDAHDPRIEN--AIPLmgfENLYPSYQIIKALLKNEKDLEidkdHLMVI--SPDt 216

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183 180 -AAKRAQSYAERLRLGLAVIHGEaqcteldmddgRHSPPMVKNatvhpglelplmmakeKPPITVV----GDVGGRIAII 254
Cdd:PRK06827 217 gAMDRAKYYASVLGVDLGLFYKR-----------RDYSRVVNG----------------RNPIVAHeflgRDVEGKDVLI 269

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183 255 VDDIIDDVESFVAAAEILKERGAYKIYVMATHGiLSAEAPRLI----EESSVDEVVVTNTVPHEVQKLQCPKIKTVDISL 330
Cdd:PRK06827 270 VDDMIASGGSMIDAAKELKSRGAKKIIVAATFG-FFTNGLEKFdkayEEGYFDRIIGTNLVYHPEELLSKPWYIEVDMSK 348

                        330       340
                 ....*....|....*....|.
gi 189069183 331 ILSEAIRRIHNGESMAYLFRN 351
Cdd:PRK06827 349 LIARIIDALNHDVSLSKLLDP 369
PRK07199 PRK07199
ribose-phosphate diphosphokinase;
19-338 1.00e-14

ribose-phosphate diphosphokinase;


Pssm-ID: 235960 [Multi-domain]  Cd Length: 301  Bit Score: 73.82  E-value: 1.00e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183  19 CTELAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDvNTAVMELLIMAYALKTACARNIIGVIPY 98
Cdd:PRK07199  11 NEAAAGRLAAALGVEVGRIELHRFPDGESYVRLDSPVAGRTVVLVCSLDRP-DEKLLPLLFAAEAARELGARRVGLVAPY 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183  99 FPYSKQSKMRKRGSIVC-KLLASMLAkAGLTHIITMD--LHQ-KEIQGFFSFPVDNLRASPFLLQYIQEEIPnyrNAVIV 174
Cdd:PRK07199  90 LAYMRQDIAFHPGEAISqRHFARLLS-GSFDRLVTVDphLHRyPSLSEVYPIPAVVLSAAPAIAAWIRAHVP---RPLLI 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183 175 AksPDAAKR--AQSYAERLRLGLAVihgeaqCTELdmddgRHSPPMVK----NATVHPGlelplmmakeKPPItVVGDV- 247
Cdd:PRK07199 166 G--PDEESEqwVAAVAERAGAPHAV------LRKT-----RHGDRDVEislpDAAPWAG----------RTPV-LVDDIv 221

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189069183 248 -GGRiaiivddiiddveSFVAAAEILKERGAYKIYVMATHGILSAEAPRLIEESSVDEVVVTNTVPHEVQklqcpkikTV 326
Cdd:PRK07199 222 sTGR-------------TLIEAARQLRAAGAASPDCVVVHALFAGDAYSALAAAGIARVVSTDTVPHPSN--------AI 280

                        330
                 ....*....|..
gi 189069183 327 DISLILSEAIRR 338
Cdd:PRK07199 281 SLAPLLAEALRR 292
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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