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Conserved domains on  [gi|193787290|dbj|BAG52496|]
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unnamed protein product [Homo sapiens]

Protein Classification

J domain-containing protein( domain architecture ID 1001220)

J domain-containing protein similar to molecular chaperone DnaJ, part of the DnaK-DnaJ-GrpE system, prevents the aggregation of unfolded substrate and acts primarily by stimulating the ATPase activity of Hsp70

CATH:  1.10.287.110
Gene Ontology:  GO:0006457
PubMed:  9644977|8016869|15170475
SCOP:  4000605

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DnaJ_bact super family cl37091
chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the ...
 26-136 7.63e-44

chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the DnaK-DnaJ-GrpE chaperone system. The three components typically are encoded by consecutive genes. DnaJ homologs occur in many genomes, typically not near DnaK and GrpE-like genes; most such genes are not included by this family. Eukaryotic (mitochondrial and chloroplast) forms are not included in the scope of this family.


The actual alignment was detected with superfamily member TIGR02349:

Pssm-ID: 274090 [Multi-domain]  Cd Length: 354  Bit Score: 150.06  E-value: 7.63e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193787290   26 SYYDILGVPKSASERQIKKAFHKLAMKYHPDKNKSPDAEAKFREIAEAYETLSDANRRKEYDTLGHSAFTSGKGQRGSGS 105
Cdd:TIGR02349   1 DYYEILGVSKDASEEEIKKAYRKLAKKYHPDRNKDKEAEEKFKEINEAYEVLSDPEKRAQYDQFGHAGFNGGGGGGGGGF 80

                          90       100       110
                  ....*....|....*....|....*....|....
gi 193787290  106 SFEQSFNFN-FDDLFKDF--GFFGQNQNTGSKKR 136
Cdd:TIGR02349  81 NGFDIGFFGdFGDIFGDFfgGGGGSGRRRRSGPR 114
 
Name Accession Description Interval E-value
DnaJ_bact TIGR02349
chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the ...
 26-136 7.63e-44

chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the DnaK-DnaJ-GrpE chaperone system. The three components typically are encoded by consecutive genes. DnaJ homologs occur in many genomes, typically not near DnaK and GrpE-like genes; most such genes are not included by this family. Eukaryotic (mitochondrial and chloroplast) forms are not included in the scope of this family.


Pssm-ID: 274090 [Multi-domain]  Cd Length: 354  Bit Score: 150.06  E-value: 7.63e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193787290   26 SYYDILGVPKSASERQIKKAFHKLAMKYHPDKNKSPDAEAKFREIAEAYETLSDANRRKEYDTLGHSAFTSGKGQRGSGS 105
Cdd:TIGR02349   1 DYYEILGVSKDASEEEIKKAYRKLAKKYHPDRNKDKEAEEKFKEINEAYEVLSDPEKRAQYDQFGHAGFNGGGGGGGGGF 80

                          90       100       110
                  ....*....|....*....|....*....|....
gi 193787290  106 SFEQSFNFN-FDDLFKDF--GFFGQNQNTGSKKR 136
Cdd:TIGR02349  81 NGFDIGFFGdFGDIFGDFfgGGGGSGRRRRSGPR 114
PRK14291 PRK14291
chaperone protein DnaJ; Provisional
 23-136 4.03e-39

chaperone protein DnaJ; Provisional


Pssm-ID: 237661 [Multi-domain]  Cd Length: 382  Bit Score: 138.36  E-value: 4.03e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193787290  23 ASKSYYDILGVPKSASERQIKKAFHKLAMKYHPDKNKSPDAEAKFREIAEAYETLSDANRRKEYDTLGHSAFTSGKGQRG 102
Cdd:PRK14291   1 AKKDYYEILGVSRNATQEEIKKAYRRLARKYHPDFNKNPEAEEKFKEINEAYQVLSDPEKRKLYDQFGHAAFSGSGQQQQ 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 193787290 103 SGSSFEQSFNFNFDDLFKD----FGF---FGQNQNTGSKKR 136
Cdd:PRK14291  81 GQEGFSDFGGGNIEDILEDvfdiFGFgdiFGRRRATRERRK 121
DnaJ COG0484
DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational ...
 26-93 1.30e-35

DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440252 [Multi-domain]  Cd Length: 139  Bit Score: 122.89  E-value: 1.30e-35
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 193787290  26 SYYDILGVPKSASERQIKKAFHKLAMKYHPDKNKS-PDAEAKFREIAEAYETLSDANRRKEYDTLGHSA 93
Cdd:COG0484    1 DYYEILGVSRDASAEEIKKAYRKLAKKYHPDRNPGdPEAEEKFKEINEAYEVLSDPEKRAAYDRFGHAA 69
DnaJ pfam00226
DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is ...
 26-87 3.62e-35

DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens, although not in Prosite are confirmed as DnaJ containing domains from literature.


Pssm-ID: 395170 [Multi-domain]  Cd Length: 63  Bit Score: 119.11  E-value: 3.62e-35
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 193787290   26 SYYDILGVPKSASERQIKKAFHKLAMKYHPDKN-KSPDAEAKFREIAEAYETLSDANRRKEYD 87
Cdd:pfam00226   1 DYYEILGVSPDASDEEIKKAYRKLALKYHPDKNpGDPEAEEKFKEINEAYEVLSDPEKRAIYD 63
terminal_TopJ NF037946
terminal organelle assembly protein TopJ;
25-177 5.19e-31

terminal organelle assembly protein TopJ;


Pssm-ID: 468284 [Multi-domain]  Cd Length: 440  Bit Score: 118.00  E-value: 5.19e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193787290  25 KSYYDILGVPKSASERQIKKAFHKLAMKYHPDKNKSPDAEAKFREIAEAYETLSDANRRKEYDTLGHsaftsgkgqrgSG 104
Cdd:NF037946   5 RDYYEVLGVDRDADDQEIKKAFRKLAKKYHPDRNKAPDAAEIFAEINEAYEVLSNPEKRANYDKYGH-----------DG 73

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 193787290 105 SSFEQSFNFNFDDLFKDfgFFGQNQNTGSKKRFENHFQTRQDGGSSRQRHHFQEFSFGGGLfDDMFEDMEKMF 177
Cdd:NF037946  74 VDGEGGFGFDAFDVFSS--FFETINKSGAFLDDSVDESVSADDDLDRLFDDSKEPSFTSGL-DEIVQFWEAFI 143
DnaJ smart00271
DnaJ molecular chaperone homology domain;
25-82 1.09e-26

DnaJ molecular chaperone homology domain;


Pssm-ID: 197617 [Multi-domain]  Cd Length: 60  Bit Score: 97.31  E-value: 1.09e-26
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 193787290    25 KSYYDILGVPKSASERQIKKAFHKLAMKYHPDKNKS--PDAEAKFREIAEAYETLSDANR 82
Cdd:smart00271   1 TDYYEILGVPRDASLDEIKKAYRKLALKYHPDKNPGdkEEAEEKFKEINEAYEVLSDPEK 60
DnaJ cd06257
DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and ...
 27-79 2.41e-26

DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, an important chaperonine family. Hsp40 proteins are characterized by the presence of a J domain, which mediates the interaction with Hsp70. They may contain other domains as well, and the architectures provide a means of classification.


Pssm-ID: 99751 [Multi-domain]  Cd Length: 55  Bit Score: 96.08  E-value: 2.41e-26
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 193787290  27 YYDILGVPKSASERQIKKAFHKLAMKYHPDKNKS-PDAEAKFREIAEAYETLSD 79
Cdd:cd06257    2 YYDILGVPPDASDEEIKKAYRKLALKYHPDKNPDdPEAEEKFKEINEAYEVLSD 55
 
Name Accession Description Interval E-value
DnaJ_bact TIGR02349
chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the ...
 26-136 7.63e-44

chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the DnaK-DnaJ-GrpE chaperone system. The three components typically are encoded by consecutive genes. DnaJ homologs occur in many genomes, typically not near DnaK and GrpE-like genes; most such genes are not included by this family. Eukaryotic (mitochondrial and chloroplast) forms are not included in the scope of this family.


Pssm-ID: 274090 [Multi-domain]  Cd Length: 354  Bit Score: 150.06  E-value: 7.63e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193787290   26 SYYDILGVPKSASERQIKKAFHKLAMKYHPDKNKSPDAEAKFREIAEAYETLSDANRRKEYDTLGHSAFTSGKGQRGSGS 105
Cdd:TIGR02349   1 DYYEILGVSKDASEEEIKKAYRKLAKKYHPDRNKDKEAEEKFKEINEAYEVLSDPEKRAQYDQFGHAGFNGGGGGGGGGF 80

                          90       100       110
                  ....*....|....*....|....*....|....
gi 193787290  106 SFEQSFNFN-FDDLFKDF--GFFGQNQNTGSKKR 136
Cdd:TIGR02349  81 NGFDIGFFGdFGDIFGDFfgGGGGSGRRRRSGPR 114
PRK14291 PRK14291
chaperone protein DnaJ; Provisional
 23-136 4.03e-39

chaperone protein DnaJ; Provisional


Pssm-ID: 237661 [Multi-domain]  Cd Length: 382  Bit Score: 138.36  E-value: 4.03e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193787290  23 ASKSYYDILGVPKSASERQIKKAFHKLAMKYHPDKNKSPDAEAKFREIAEAYETLSDANRRKEYDTLGHSAFTSGKGQRG 102
Cdd:PRK14291   1 AKKDYYEILGVSRNATQEEIKKAYRRLARKYHPDFNKNPEAEEKFKEINEAYQVLSDPEKRKLYDQFGHAAFSGSGQQQQ 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 193787290 103 SGSSFEQSFNFNFDDLFKD----FGF---FGQNQNTGSKKR 136
Cdd:PRK14291  81 GQEGFSDFGGGNIEDILEDvfdiFGFgdiFGRRRATRERRK 121
PRK10767 PRK10767
chaperone protein DnaJ; Provisional
 23-136 5.14e-39

chaperone protein DnaJ; Provisional


Pssm-ID: 236757 [Multi-domain]  Cd Length: 371  Bit Score: 137.97  E-value: 5.14e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193787290  23 ASKSYYDILGVPKSASERQIKKAFHKLAMKYHPDKNK-SPDAEAKFREIAEAYETLSDANRRKEYDTLGHSAFTSGKGQR 101
Cdd:PRK10767   2 AKRDYYEVLGVSRNASEDEIKKAYRKLAMKYHPDRNPgDKEAEEKFKEIKEAYEVLSDPQKRAAYDQYGHAAFEQGGGGG 81

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 193787290 102 GSGSSfeQSFNFNFDDLFKDfgFFGQNQNTGSKKR 136
Cdd:PRK10767  82 GFGGG--GGFGDIFGDIFGD--IFGGGRGGGRQRA 112
DnaJ COG0484
DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational ...
 26-93 1.30e-35

DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440252 [Multi-domain]  Cd Length: 139  Bit Score: 122.89  E-value: 1.30e-35
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 193787290  26 SYYDILGVPKSASERQIKKAFHKLAMKYHPDKNKS-PDAEAKFREIAEAYETLSDANRRKEYDTLGHSA 93
Cdd:COG0484    1 DYYEILGVSRDASAEEIKKAYRKLAKKYHPDRNPGdPEAEEKFKEINEAYEVLSDPEKRAAYDRFGHAA 69
DnaJ pfam00226
DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is ...
 26-87 3.62e-35

DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens, although not in Prosite are confirmed as DnaJ containing domains from literature.


Pssm-ID: 395170 [Multi-domain]  Cd Length: 63  Bit Score: 119.11  E-value: 3.62e-35
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 193787290   26 SYYDILGVPKSASERQIKKAFHKLAMKYHPDKN-KSPDAEAKFREIAEAYETLSDANRRKEYD 87
Cdd:pfam00226   1 DYYEILGVSPDASDEEIKKAYRKLALKYHPDKNpGDPEAEEKFKEINEAYEVLSDPEKRAIYD 63
PRK14280 PRK14280
molecular chaperone DnaJ;
22-139 1.59e-31

molecular chaperone DnaJ;


Pssm-ID: 237656 [Multi-domain]  Cd Length: 376  Bit Score: 118.29  E-value: 1.59e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193787290  22 LASKSYYDILGVPKSASERQIKKAFHKLAMKYHPDKNKSPDAEAKFREIAEAYETLSDANRRKEYDTLGHSAFTSG-KGQ 100
Cdd:PRK14280   1 MAKRDYYEVLGVSKSASKDEIKKAYRKLSKKYHPDINKEEGADEKFKEISEAYEVLSDDQKRAQYDQFGHAGPNQGfGGG 80

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 193787290 101 RGSGSSFeqSFNFNFDDLFKDFgFFGqnqntGSKKRFEN 139
Cdd:PRK14280  81 GFGGGDF--GGGFGFEDIFSSF-FGG-----GGRRRDPN 111
PRK14283 PRK14283
chaperone protein DnaJ; Provisional
 21-151 2.75e-31

chaperone protein DnaJ; Provisional


Pssm-ID: 184604 [Multi-domain]  Cd Length: 378  Bit Score: 117.62  E-value: 2.75e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193787290  21 ILASKSYYDILGVPKSASERQIKKAFHKLAMKYHPDKNKSPDAEAKFREIAEAYETLSDANRRKEYDTLGHSAFtsgkgq 100
Cdd:PRK14283   1 MAEKRDYYEVLGVDRNADKKEIKKAYRKLARKYHPDVSEEEGAEEKFKEISEAYAVLSDDEKRQRYDQFGHAGM------ 74

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 193787290 101 rgSGSSFEQSF-NFNFDDLFKDFGFfgqnqntgskkRFENHFQTRQDGGSSR 151
Cdd:PRK14283  75 --DGFSQEDIFnNINFEDIFQGFGF-----------GIGNIFDMFGFGGGSR 113
PRK14298 PRK14298
chaperone protein DnaJ; Provisional
 24-126 2.96e-31

chaperone protein DnaJ; Provisional


Pssm-ID: 184612 [Multi-domain]  Cd Length: 377  Bit Score: 117.64  E-value: 2.96e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193787290  24 SKSYYDILGVPKSASERQIKKAFHKLAMKYHPDKNKSPDAEAKFREIAEAYETLSDANRRKEYDTLGHSAFTSgkgqrgs 103
Cdd:PRK14298   4 TRDYYEILGLSKDASVEDIKKAYRKLAMKYHPDKNKEPDAEEKFKEISEAYAVLSDAEKRAQYDRFGHAGIDN------- 76

                         90       100
                 ....*....|....*....|....*
gi 193787290 104 gssfeqsfNFNFDDLFK--DFGFFG 126
Cdd:PRK14298  77 --------QYSAEDIFRgaDFGGFG 93
PRK14295 PRK14295
molecular chaperone DnaJ;
25-119 3.88e-31

molecular chaperone DnaJ;


Pssm-ID: 237665 [Multi-domain]  Cd Length: 389  Bit Score: 117.64  E-value: 3.88e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193787290  25 KSYYDILGVPKSASERQIKKAFHKLAMKYHPDKNK-SPDAEAKFREIAEAYETLSDANRRKEYDTlGHSAFTSGKGQRGS 103
Cdd:PRK14295   9 KDYYKVLGVPKDATEAEIKKAYRKLAREYHPDANKgDAKAEERFKEISEAYDVLSDEKKRKEYDE-ARSLFGNGGFRPGP 87

                         90
                 ....*....|....*.
gi 193787290 104 GSSFEQSFNFNFDDLF 119
Cdd:PRK14295  88 GGGGGGGFNFDLGDLF 103
terminal_TopJ NF037946
terminal organelle assembly protein TopJ;
25-177 5.19e-31

terminal organelle assembly protein TopJ;


Pssm-ID: 468284 [Multi-domain]  Cd Length: 440  Bit Score: 118.00  E-value: 5.19e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193787290  25 KSYYDILGVPKSASERQIKKAFHKLAMKYHPDKNKSPDAEAKFREIAEAYETLSDANRRKEYDTLGHsaftsgkgqrgSG 104
Cdd:NF037946   5 RDYYEVLGVDRDADDQEIKKAFRKLAKKYHPDRNKAPDAAEIFAEINEAYEVLSNPEKRANYDKYGH-----------DG 73

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 193787290 105 SSFEQSFNFNFDDLFKDfgFFGQNQNTGSKKRFENHFQTRQDGGSSRQRHHFQEFSFGGGLfDDMFEDMEKMF 177
Cdd:NF037946  74 VDGEGGFGFDAFDVFSS--FFETINKSGAFLDDSVDESVSADDDLDRLFDDSKEPSFTSGL-DEIVQFWEAFI 143
PRK14276 PRK14276
chaperone protein DnaJ; Provisional
 22-127 7.07e-31

chaperone protein DnaJ; Provisional


Pssm-ID: 237653 [Multi-domain]  Cd Length: 380  Bit Score: 116.73  E-value: 7.07e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193787290  22 LASKSYYDILGVPKSASERQIKKAFHKLAMKYHPDKNKSPDAEAKFREIAEAYETLSDANRRKEYDTLGHSAFTSGKGQR 101
Cdd:PRK14276   1 MNNTEYYDRLGVSKDASQDEIKKAYRKLSKKYHPDINKEPGAEEKYKEVQEAYETLSDPQKRAAYDQYGAAGANGGFGGG 80

                         90       100
                 ....*....|....*....|....*...
gi 193787290 102 GSG-SSFEQSFNF-NFDDLFKDFgFFGQ 127
Cdd:PRK14276  81 AGGfGGFDGSGGFgGFEDIFSSF-FGGG 107
PRK14299 PRK14299
chaperone protein DnaJ; Provisional
 22-126 1.81e-30

chaperone protein DnaJ; Provisional


Pssm-ID: 237667 [Multi-domain]  Cd Length: 291  Bit Score: 113.88  E-value: 1.81e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193787290  22 LASKSYYDILGVPKSASERQIKKAFHKLAMKYHPDKNKSPDAEAKFREIAEAYETLSDANRRKEYDTLGHSAFTSG---- 97
Cdd:PRK14299   1 MAYKDYYAILGVPKNASQDEIKKAFKKLARKYHPDVNKSPGAEEKFKEINEAYTVLSDPEKRRIYDTYGTTAASAGwqgp 80

                         90       100       110
                 ....*....|....*....|....*....|...
gi 193787290  98 -KGQRGSG--SSFE-QSFNFNFDDLFKDFGFFG 126
Cdd:PRK14299  81 pPGPPGGGdfSGFNvGDFSDFFQQLFGGRGGFG 113
PRK14277 PRK14277
chaperone protein DnaJ; Provisional
 21-126 1.36e-29

chaperone protein DnaJ; Provisional


Pssm-ID: 184599 [Multi-domain]  Cd Length: 386  Bit Score: 113.36  E-value: 1.36e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193787290  21 ILASKSYYDILGVPKSASERQIKKAFHKLAMKYHPDKNK-SPDAEAKFREIAEAYETLSDANRRKEYDTLGHSAFTSGKG 99
Cdd:PRK14277   1 MAAKKDYYEILGVDRNATEEEIKKAYRRLAKKYHPDLNPgDKEAEQKFKEINEAYEILSDPQKRAQYDQFGHAAFDPGGF 80

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 193787290 100 QRG--SGSSFEQSFnFNFD-----DLFKDF--GFFG 126
Cdd:PRK14277  81 GQGgfGQGGFGGGG-FDFDfggfgDIFEDIfgDFFG 115
PRK14286 PRK14286
chaperone protein DnaJ; Provisional
 22-133 1.88e-29

chaperone protein DnaJ; Provisional


Pssm-ID: 172774 [Multi-domain]  Cd Length: 372  Bit Score: 112.78  E-value: 1.88e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193787290  22 LASKSYYDILGVPKSASERQIKKAFHKLAMKYHPDKNK-SPDAEAKFREIAEAYETLSDANRRKEYDTLGHSAFTSGKGQ 100
Cdd:PRK14286   1 MSERSYYDILGVSKSANDEEIKSAYRKLAIKYHPDKNKgNKESEEKFKEATEAYEILRDPKKRQAYDQFGKAGVNAGAGG 80

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 193787290 101 RGSGSSFEqsfnfnFDDLFKDFG-----FFGQNQNTGS 133
Cdd:PRK14286  81 FGQGAYTD------FSDIFGDFGdifgdFFGGGRGGGS 112
PRK14294 PRK14294
chaperone protein DnaJ; Provisional
 27-136 2.61e-29

chaperone protein DnaJ; Provisional


Pssm-ID: 237664 [Multi-domain]  Cd Length: 366  Bit Score: 112.17  E-value: 2.61e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193787290  27 YYDILGVPKSASERQIKKAFHKLAMKYHPDKNK-SPDAEAKFREIAEAYETLSDANRRKEYDTLGHSAFtSGKGQRGSGs 105
Cdd:PRK14294   6 YYEILGVTRDASEEEIKKSYRKLAMKYHPDRNPgDKEAEELFKEAAEAYEVLSDPKKRGIYDQYGHEGL-SGTGFSGFS- 83

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 193787290 106 sfeqsfnfNFDDLFKDFG-----FFGQNQNTGSKKR 136
Cdd:PRK14294  84 --------GFDDIFSSFGdifedFFGFGGGRRGRSR 111
PRK14297 PRK14297
molecular chaperone DnaJ;
22-136 2.81e-29

molecular chaperone DnaJ;


Pssm-ID: 184611 [Multi-domain]  Cd Length: 380  Bit Score: 112.18  E-value: 2.81e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193787290  22 LASKSYYDILGVPKSASERQIKKAFHKLAMKYHPDKNK-SPDAEAKFREIAEAYETLSDANRRKEYDTLGHSAFTSGKGQ 100
Cdd:PRK14297   1 MASKDYYEVLGLEKGASDDEIKKAFRKLAIKYHPDKNKgNKEAEEKFKEINEAYQVLSDPQKKAQYDQFGTADFNGAGGF 80

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 193787290 101 RGSG-SSFEQSFNFNFDDLFKdfGFFGQNQNTGSKKR 136
Cdd:PRK14297  81 GSGGfGGFDFSDMGGFGDIFD--SFFGGGFGSSSRRR 115
PRK14285 PRK14285
chaperone protein DnaJ; Provisional
 25-144 9.32e-29

chaperone protein DnaJ; Provisional


Pssm-ID: 172773 [Multi-domain]  Cd Length: 365  Bit Score: 110.85  E-value: 9.32e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193787290  25 KSYYDILGVPKSASERQIKKAFHKLAMKYHPDKNK-SPDAEAKFREIAEAYETLSDANRRKEYDTLGHSAFTSGKGQRGS 103
Cdd:PRK14285   3 RDYYEILGLSKGASKDEIKKAYRKIAIKYHPDKNKgNKEAESIFKEATEAYEVLIDDNKRAQYDRFGHTAFEGGGGFEGF 82

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 193787290 104 GSSFEqsfnfNFDDLFKDFGFFGQNQNTGSKKRFENHFQTR 144
Cdd:PRK14285  83 SGGFS-----GFSDIFEDFGDIFDSFFTGNRGQDKNRKHEK 118
PRK14289 PRK14289
molecular chaperone DnaJ;
23-137 4.92e-28

molecular chaperone DnaJ;


Pssm-ID: 237660 [Multi-domain]  Cd Length: 386  Bit Score: 109.15  E-value: 4.92e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193787290  23 ASKSYYDILGVPKSASERQIKKAFHKLAMKYHPDKNK-SPDAEAKFREIAEAYETLSDANRRKEYDTLGH---SAFTSGK 98
Cdd:PRK14289   3 EKRDYYEVLGVSKTATVDEIKKAYRKKAIQYHPDKNPgDKEAEEKFKEAAEAYDVLSDPDKRSRYDQFGHagvGGAAGGG 82

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 193787290  99 GQRGSGSSFEQSFNfNFDDLFKDF-----GFFGQNQNTGSKKRF 137
Cdd:PRK14289  83 GFSGEGMSMEDIFS-MFGDIFGGHgggfgGFGGFGGGGSQQRVF 125
PRK14281 PRK14281
chaperone protein DnaJ; Provisional
 25-153 1.30e-27

chaperone protein DnaJ; Provisional


Pssm-ID: 237657 [Multi-domain]  Cd Length: 397  Bit Score: 107.97  E-value: 1.30e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193787290  25 KSYYDILGVPKSASERQIKKAFHKLAMKYHPDKN-KSPDAEAKFREIAEAYETLSDANRRKEYDTLGHSAFTS------G 97
Cdd:PRK14281   3 RDYYEVLGVSRSADKDEIKKAYRKLALKYHPDKNpDNKEAEEHFKEVNEAYEVLSNDDKRRRYDQFGHAGVGSsaasggG 82

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 193787290  98 KGQRGSGSSFEQSFNfNFDDLFKDfgffGQNQNTGSKKRFENHFqtrqDGGSSRQR 153
Cdd:PRK14281  83 PGYGGGGGDFNDIFS-AFNDMFGG----GARRGGGSPFGFEDVF----GGGGRRRR 129
PRK14296 PRK14296
chaperone protein DnaJ; Provisional
 22-131 1.32e-27

chaperone protein DnaJ; Provisional


Pssm-ID: 237666 [Multi-domain]  Cd Length: 372  Bit Score: 107.72  E-value: 1.32e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193787290  22 LASKSYYDILGVPKSASERQIKKAFHKLAMKYHPDKNKSPDAEAKFREIAEAYETLSDANRRKEYDTLGHSAFTSGKGQR 101
Cdd:PRK14296   1 MKKKDYYEVLGVSKTASEQEIRQAYRKLAKQYHPDLNKSPDAHDKMVEINEAADVLLDKDKRKQYDQFGHAAFDGSSGFS 80

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 193787290 102 GSGSSFEQSFN-------FNFDDLFKDfgFFGQNQNT 131
Cdd:PRK14296  81 SNFGDFEDLFSnmgssgfSSFTNIFSD--FFGSNKSD 115
PRK14301 PRK14301
chaperone protein DnaJ; Provisional
 25-126 1.45e-27

chaperone protein DnaJ; Provisional


Pssm-ID: 237668 [Multi-domain]  Cd Length: 373  Bit Score: 107.52  E-value: 1.45e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193787290  25 KSYYDILGVPKSASERQIKKAFHKLAMKYHPDKN-KSPDAEAKFREIAEAYETLSDANRRKEYDTLGHSAFTSGKGQRGS 103
Cdd:PRK14301   4 RDYYEVLGVSRDASEDEIKKAYRKLALQYHPDRNpDNPEAEQKFKEAAEAYEVLRDAEKRARYDRFGHAGVNGNGGFGGF 83

                         90       100
                 ....*....|....*....|....
gi 193787290 104 GSSfEQSFNfNFDDLFKD-FGFFG 126
Cdd:PRK14301  84 SSA-EDIFS-HFSDIFGDlFGFSG 105
PRK10266 PRK10266
curved DNA-binding protein;
25-154 2.73e-27

curved DNA-binding protein;


Pssm-ID: 182347 [Multi-domain]  Cd Length: 306  Bit Score: 105.67  E-value: 2.73e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193787290  25 KSYYDILGVPKSASERQIKKAFHKLAMKYHPDKNKSPDAEAKFREIAEAYETLSDANRRKEYDTLGHSAFTSGKG---QR 101
Cdd:PRK10266   4 KDYYAIMGVKPTDDLKTIKTAYRRLARKYHPDVSKEPDAEARFKEVAEAWEVLSDEQRRAEYDQLWQHRNDPQFNrqfQH 83

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 193787290 102 GSGSSFEQSfnfNFDDLFKDfgFFGQNqntgskkrfenhfqtrqdGGSSRQRH 154
Cdd:PRK10266  84 GDGQSFNAE---DFDDIFSS--IFGQH------------------ARQSRQRP 113
PRK14282 PRK14282
chaperone protein DnaJ; Provisional
 23-136 4.32e-27

chaperone protein DnaJ; Provisional


Pssm-ID: 184603 [Multi-domain]  Cd Length: 369  Bit Score: 106.42  E-value: 4.32e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193787290  23 ASKSYYDILGVPKSASERQIKKAFHKLAMKYHPDKN--KSPDAEAKFREIAEAYETLSDANRRKEYDTLGHSAFTSGKGQ 100
Cdd:PRK14282   2 EKKDYYEILGVSRNATQEEIKRAYKRLVKEWHPDRHpeNRKEAEQKFKEIQEAYEVLSDPQKRAMYDRFGYVGEQPPYQE 81

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 193787290 101 RGSGSSFeqsfnfnFDDLFKDFG----------FFGqNQNTGSKKR 136
Cdd:PRK14282  82 TESGGGF-------FEDIFKDFEnifnrdifdiFFG-ERRTQEEQR 119
PRK14300 PRK14300
chaperone protein DnaJ; Provisional
 24-136 5.64e-27

chaperone protein DnaJ; Provisional


Pssm-ID: 172788 [Multi-domain]  Cd Length: 372  Bit Score: 105.87  E-value: 5.64e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193787290  24 SKSYYDILGVPKSASERQIKKAFHKLAMKYHPDKNKSPDAEAKFREIAEAYETLSDANRRKEYDTLGHSAFTSGKGQRGS 103
Cdd:PRK14300   2 SQDYYQILGVSKTASQADLKKAYLKLAKQYHPDTTDAKDAEKKFKEINAAYDVLKDEQKRAAYDRFGHDAFQNQQSRGGG 81

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 193787290 104 G--SSFEQSFNFNFDDLFKDF-GFFGQNQNTGSKKR 136
Cdd:PRK14300  82 GnhGGFHPDINDIFGDFFSDFmGGSRRSRPTSSKVR 117
SEC63 COG5407
Preprotein translocase subunit Sec63 [Intracellular trafficking, secretion, and vesicular ...
 27-85 9.42e-27

Preprotein translocase subunit Sec63 [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 444165 [Multi-domain]  Cd Length: 61  Bit Score: 97.38  E-value: 9.42e-27
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 193787290  27 YYDILGVPKSASERQIKKAFHKLAMKYHPDKNK-SPDAEAKFREIAEAYETLSDANRRKE 85
Cdd:COG5407    2 PYEVLGVAKTASADEIKKAYRKLAKKYHPDRNKgDPKAEERFKEINEAYELLSDAEKRAR 61
DnaJ smart00271
DnaJ molecular chaperone homology domain;
25-82 1.09e-26

DnaJ molecular chaperone homology domain;


Pssm-ID: 197617 [Multi-domain]  Cd Length: 60  Bit Score: 97.31  E-value: 1.09e-26
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 193787290    25 KSYYDILGVPKSASERQIKKAFHKLAMKYHPDKNKS--PDAEAKFREIAEAYETLSDANR 82
Cdd:smart00271   1 TDYYEILGVPRDASLDEIKKAYRKLALKYHPDKNPGdkEEAEEKFKEINEAYEVLSDPEK 60
DnaJ cd06257
DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and ...
 27-79 2.41e-26

DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, an important chaperonine family. Hsp40 proteins are characterized by the presence of a J domain, which mediates the interaction with Hsp70. They may contain other domains as well, and the architectures provide a means of classification.


Pssm-ID: 99751 [Multi-domain]  Cd Length: 55  Bit Score: 96.08  E-value: 2.41e-26
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 193787290  27 YYDILGVPKSASERQIKKAFHKLAMKYHPDKNKS-PDAEAKFREIAEAYETLSD 79
Cdd:cd06257    2 YYDILGVPPDASDEEIKKAYRKLALKYHPDKNPDdPEAEEKFKEINEAYEVLSD 55
PRK14293 PRK14293
molecular chaperone DnaJ;
27-136 4.00e-25

molecular chaperone DnaJ;


Pssm-ID: 237663 [Multi-domain]  Cd Length: 374  Bit Score: 100.83  E-value: 4.00e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193787290  27 YYDILGVPKSASERQIKKAFHKLAMKYHPDKNKSPDAEAKFREIAEAYETLSDANRRKEYDTLGHSAFTSGKGQRGSGSS 106
Cdd:PRK14293   5 YYEILGVSRDADKDELKRAYRRLARKYHPDVNKEPGAEDRFKEINRAYEVLSDPETRARYDQFGEAGVSGAAGFPDMGDM 84

                         90       100       110
                 ....*....|....*....|....*....|..
gi 193787290 107 feqsfnFNFDDLFKDF--GFFGQNQNTGSKKR 136
Cdd:PRK14293  85 ------GGFADIFETFfsGFGGAGGQGGRRRR 110
PRK14284 PRK14284
chaperone protein DnaJ; Provisional
 27-223 1.20e-24

chaperone protein DnaJ; Provisional


Pssm-ID: 237658 [Multi-domain]  Cd Length: 391  Bit Score: 99.92  E-value: 1.20e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193787290  27 YYDILGVPKSASERQIKKAFHKLAMKYHPDKNK-SPDAEAKFREIAEAYETLSDANRRKEYDTLGHSAFTSGKGQRGsGS 105
Cdd:PRK14284   3 YYTILGVSKTASPEEIKKAYRKLAVKYHPDKNPgDAEAEKRFKEVSEAYEVLSDAQKRESYDRYGKDGPFAGAGGFG-GA 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193787290 106 SFEqsfnfNFDDLFKDF-GFFGQNQNtGSKKRFE-------NHFQTRQDGGSSRQ----RHHFQEfsfgggLFDDMFEDM 173
Cdd:PRK14284  82 GMG-----NMEDALRTFmGAFGGEFG-GGGSFFEglfgglgEAFGMRGGPAGARQgaskKVHITL------SFEEAAKGV 149

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 193787290 174 EKMFSFSGFDS---------TNQHTVQTENRFHGSSKhcrtVTQRRG--NMVTTYTDCSGQ 223
Cdd:PRK14284 150 EKELLVSGYKScdacsgsgaNSSQGIKVCDRCKGSGQ----VVQSRGffSMASTCPECGGE 206
CbpA COG2214
Curved DNA-binding protein CbpA, contains a DnaJ-like domain [Transcription];
25-96 1.51e-24

Curved DNA-binding protein CbpA, contains a DnaJ-like domain [Transcription];


Pssm-ID: 441816 [Multi-domain]  Cd Length: 91  Bit Score: 92.86  E-value: 1.51e-24
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 193787290  25 KSYYDILGVPKSASERQIKKAFHKLAMKYHPDKNKSPD--AEAKFREIAEAYETLSDANRRKEYDT-LGHSAFTS 96
Cdd:COG2214    5 KDHYAVLGVPPDASLEEIRQAYRRLAKLLHPDRGGELKalAEELFQRLNEAYEVLSDPERRAEYDReLGQSGKGS 79
PRK14287 PRK14287
chaperone protein DnaJ; Provisional
 22-122 2.54e-24

chaperone protein DnaJ; Provisional


Pssm-ID: 237659 [Multi-domain]  Cd Length: 371  Bit Score: 98.93  E-value: 2.54e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193787290  22 LASKSYYDILGVPKSASERQIKKAFHKLAMKYHPDKNKSPDAEAKFREIAEAYETLSDANRRKEYDTLGHSAFTSGKGQR 101
Cdd:PRK14287   1 MSKRDYYEVLGVDRNASVDEVKKAYRKLARKYHPDVNKAPDAEDKFKEVKEAYDTLSDPQKKAHYDQFGHTDPNQGFGGG 80

                         90       100
                 ....*....|....*....|.
gi 193787290 102 GSGssfeqSFNfNFDDLFKDF 122
Cdd:PRK14287  81 GAG-----DFG-GFSDIFDMF 95
PRK14278 PRK14278
chaperone protein DnaJ; Provisional
 24-126 9.39e-24

chaperone protein DnaJ; Provisional


Pssm-ID: 237654 [Multi-domain]  Cd Length: 378  Bit Score: 97.43  E-value: 9.39e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193787290  24 SKSYYDILGVPKSASERQIKKAFHKLAMKYHPDKNKSPDAEAKFREIAEAYETLSDANRRKEYDtLGHSAFTSGKgqrGS 103
Cdd:PRK14278   2 ARDYYGLLGVSRNASDAEIKRAYRKLARELHPDVNPDEEAQEKFKEISVAYEVLSDPEKRRIVD-LGGDPLESAG---GG 77

                         90       100
                 ....*....|....*....|...
gi 193787290 104 GSSFEQSFNfNFDDLFKdfGFFG 126
Cdd:PRK14278  78 GGGFGGGFG-GLGDVFE--AFFG 97
PRK14290 PRK14290
chaperone protein DnaJ; Provisional
 24-128 7.11e-23

chaperone protein DnaJ; Provisional


Pssm-ID: 172778 [Multi-domain]  Cd Length: 365  Bit Score: 94.61  E-value: 7.11e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193787290  24 SKSYYDILGVPKSASERQIKKAFHKLAMKYHPDKN--KSPDAEAKFREIAEAYETLSDANRRKEYDTLGHSAFTSGkgqr 101
Cdd:PRK14290   2 AKDYYKILGVDRNASQEDIKKAFRELAKKWHPDLHpgNKAEAEEKFKEISEAYEVLSDPQKRRQYDQTGTVDFGAG---- 77

                         90       100
                 ....*....|....*....|....*...
gi 193787290 102 GSGSSFEQSFNF-NFDDLFKDfgFFGQN 128
Cdd:PRK14290  78 GSNFNWDNFTHFsDINDIFNQ--IFGGN 103
PRK14279 PRK14279
molecular chaperone DnaJ;
23-152 1.20e-22

molecular chaperone DnaJ;


Pssm-ID: 237655 [Multi-domain]  Cd Length: 392  Bit Score: 94.41  E-value: 1.20e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193787290  23 ASKSYYDILGVPKSASERQIKKAFHKLAMKYHPDKNK-SPDAEAKFREIAEAYETLSDANRRKEYDTL---------GHS 92
Cdd:PRK14279   7 VEKDFYKELGVSSDASAEEIKKAYRKLARELHPDANPgDPAAEERFKAVSEAHDVLSDPAKRKEYDETrrlfagggfGGR 86

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 193787290  93 AFTSGKGQRGSGSSfEQSFNFNFDDLfkdFGFFGQNQNTGSKKRFENHFQTrqdGGSSRQ 152
Cdd:PRK14279  87 RFDGGGGFGGFGTG-GDGAEFNLNDL---FDAAGRGGGGGIGDLFGGLFNR---GGGSAR 139
PRK14292 PRK14292
chaperone protein DnaJ; Provisional
 27-136 1.12e-20

chaperone protein DnaJ; Provisional


Pssm-ID: 237662 [Multi-domain]  Cd Length: 371  Bit Score: 88.79  E-value: 1.12e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193787290  27 YYDILGVPKSASERQIKKAFHKLAMKYHPDKNKSPDAEAKFREIAEAYETLSDANRRKEYDTLGHSaftSGKGQRGsGSS 106
Cdd:PRK14292   4 YYELLGVSRTASADEIKSAYRKLALKYHPDRNKEKGAAEKFAQINEAYAVLSDAEKRAHYDRFGTA---PGAGMPG-GDP 79

                         90       100       110
                 ....*....|....*....|....*....|
gi 193787290 107 FeQSFNFNFDDLFKDFgFFGQNQNTGSKKR 136
Cdd:PRK14292  80 F-GGMGFDPMDIFEQL-FGGAGFGGGRGRR 107
PTZ00037 PTZ00037
DnaJ_C chaperone protein; Provisional
 24-139 5.62e-19

DnaJ_C chaperone protein; Provisional


Pssm-ID: 240236 [Multi-domain]  Cd Length: 421  Bit Score: 84.49  E-value: 5.62e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193787290  24 SKSYYDILGVPKSASERQIKKAFHKLAMKYHPDKNKSPDaeaKFREIAEAYETLSDANRRKEYDTLGHsaftsgKGQRGS 103
Cdd:PTZ00037  27 NEKLYEVLNLSKDCTTSEIKKAYRKLAIKHHPDKGGDPE---KFKEISRAYEVLSDPEKRKIYDEYGE------EGLEGG 97

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 193787290 104 GSSFEQSfnfnfdDLFkDFgFFGQNQNTGSKKRFEN 139
Cdd:PTZ00037  98 EQPADAS------DLF-DL-IFGGGRKPGGKKRGED 125
PRK14288 PRK14288
molecular chaperone DnaJ;
26-125 5.38e-14

molecular chaperone DnaJ;


Pssm-ID: 172776 [Multi-domain]  Cd Length: 369  Bit Score: 69.72  E-value: 5.38e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193787290  26 SYYDILGVPKSASERQIKKAFHKLAMKYHPDKNK-SPDAEAKFREIAEAYETLSDANRRKEYDTLGhsafTSGKGQRGSG 104
Cdd:PRK14288   4 SYYEILEVEKHSNQETIKKSYRKLALKYHPDRNAgDKEAEEKFKLINEAYGVLSDEKKRALYDRYG----KKGLNQAGAS 79

                         90       100
                 ....*....|....*....|.
gi 193787290 105 SSfeqsfnfNFDDLFKDFGFF 125
Cdd:PRK14288  80 QS-------DFSDFFEDLGSF 93
DjlA COG1076
DnaJ domain-containing protein [Posttranslational modification, protein turnover, chaperones];
22-84 7.43e-14

DnaJ domain-containing protein [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440694 [Multi-domain]  Cd Length: 75  Bit Score: 64.43  E-value: 7.43e-14
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193787290  22 LASKSYYDILGVPKSASERQIKKAFHKLAMKYHPDK--NKSPD-----AEAKFREIAEAYETLSDANRRK 84
Cdd:COG1076    1 MQLDDAFELLGLPPDADDAELKRAYRKLQREHHPDRlaAGLPEeeqrlALQKAAAINEAYETLKDPRGID 70
PTZ00341 PTZ00341
Ring-infected erythrocyte surface antigen; Provisional
 27-91 7.98e-12

Ring-infected erythrocyte surface antigen; Provisional


Pssm-ID: 173534 [Multi-domain]  Cd Length: 1136  Bit Score: 64.04  E-value: 7.98e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 193787290   27 YYDILGVPKSASERQIKKAFHKLAMKYHPDKNKSPDAEAKFREIAEAYETLSDANRRKEYDTLGH 91
Cdd:PTZ00341  575 FYDILGVGVNADMKEISERYFKLAENYYPPKRSGNEGFHKFKKINEAYQILGDIDKKKMYNKFGY 639
ZUO1 COG5269
Ribosome-associated chaperone zuotin [Translation, ribosomal structure and biogenesis / ...
 28-88 3.34e-07

Ribosome-associated chaperone zuotin [Translation, ribosomal structure and biogenesis / Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 227594 [Multi-domain]  Cd Length: 379  Bit Score: 50.03  E-value: 3.34e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 193787290  28 YDILGVPK---SASERQIKKAFHKLAMKYHPDKNK---SPDAEAKFREIAEAYETLSDANRRKEYDT 88
Cdd:COG5269   46 YALLGLSKyrtKAIPPQILKAHKKKVYKYHPDKTAaggNKGCDEFFKLIQKAREVLGDRKLRLQYDS 112
hscB PRK01356
co-chaperone HscB; Provisional
 26-86 7.60e-06

co-chaperone HscB; Provisional


Pssm-ID: 167217 [Multi-domain]  Cd Length: 166  Bit Score: 44.48  E-value: 7.60e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 193787290  26 SYYDILGVPK--SASERQIKKAFHKLAMKYHPDKNKSPDAEAKFREIA----EAYETLSDANRRKEY 86
Cdd:PRK01356   3 NYFQLLGLPQeyNIDLKILEKQYFAMQVKYHPDKAKTLQEKEQNLIIAselnNAYSTLKDALKRAEY 69
djlA PRK09430
co-chaperone DjlA;
28-75 2.78e-04

co-chaperone DjlA;


Pssm-ID: 236512 [Multi-domain]  Cd Length: 267  Bit Score: 40.95  E-value: 2.78e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 193787290  28 YDILGVPKSASERQIKKAFHKLAMKYHPDK----NKSPD----AEAKFREIAEAYE 75
Cdd:PRK09430 203 YKVLGVSESDDDQEIKRAYRKLMSEHHPDKlvakGLPPEmmemAKEKAQEIQAAYE 258
hscB TIGR00714
Fe-S protein assembly co-chaperone HscB; This model describes the small subunit, Hsc20 (20K ...
 39-86 1.40e-03

Fe-S protein assembly co-chaperone HscB; This model describes the small subunit, Hsc20 (20K heat shock cognate protein) of a pair of proteins Hsc66-Hsc20, related to the DnaK-DnaJ heat shock proteins, which also serve as molecular chaperones. Hsc20, unlike DnaJ, appears not to have chaperone activity on its own, but to act solely as a regulatory subunit for Hsc66 (i.e., to be a co-chaperone). The gene for Hsc20 in E. coli, hscB, is not induced by heat shock. [Protein fate, Protein folding and stabilization]


Pssm-ID: 211601 [Multi-domain]  Cd Length: 155  Bit Score: 37.94  E-value: 1.40e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 193787290   39 ERQIKKAFHKLAMKYHPDKNKSPDAEA----KFREIAEAYETLSDANRRKEY 86
Cdd:TIGR00714   5 QSRLRKRYRQLQAQYHPDASGMAQEQLaasqQSTTLNQAYHTLKDPLRRAEY 56
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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