|
Name |
Accession |
Description |
Interval |
E-value |
| SecA |
COG0653 |
Preprotein translocase subunit SecA (ATPase, RNA helicase) [Intracellular trafficking, ... |
1-364 |
0e+00 |
|
Preprotein translocase subunit SecA (ATPase, RNA helicase) [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440418 [Multi-domain] Cd Length: 876 Bit Score: 763.03 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 1 MLGILNKMF-DPTKRTLNRYEKIANDIDAIRGDYENLSDDALKHKTIEFKERLEKGATTDDLLVEAFAVVREASRRVTGM 79
Cdd:COG0653 1 MGKLLKKIFgSRNDRELKRLRKIVDKINALEPEMEALSDEELRAKTDEFKERLANGETLDDLLPEAFAVVREASKRVLGM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 80 FPFKVQLMGGVALHDGNIAEMKTGEGKTLTSTLPVYLNALTGKGVHIVTVNEYLASRDAEQMGKIFEFLGLTVGLNLNSM 159
Cdd:COG0653 81 RHFDVQLIGGIVLHQGKIAEMKTGEGKTLVATLPAYLNALTGKGVHVVTVNDYLAKRDAEWMGRLYRFLGLSVGVIVHGM 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 160 SKDEKREAYAADITYSTNNELGFDYLRDNMVLYKEQMVQRPLHFAVIDEVDSILIDEARTPLIISGQAAKSTKLYVQANA 239
Cdd:COG0653 161 DPEERRAAYAADITYGTNNEFGFDYLRDNMVFSLEDMVQRGLNYAIVDEVDSILIDEARTPLIISGPAEDSTDLYYRINK 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 240 FVRTLKAEKDYTYDIKTKAVQLTEEGMTKAEKAFGIDNLFDVKHVALNHHINQALKAHVAMQKDVDYVVEDGQVVIVDSF 319
Cdd:COG0653 241 LVPRLKRDGDYTVDEKARTVTLTEEGIEKVEKLLGIDNLYDPENIELVHHLNQALRAHALFKRDVDYIVKDGEVVIVDEF 320
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 48980 320 TGRLMKGRRYSEGLHQAIEAKEGLEIQNESMTLATITFQNYFRMY 364
Cdd:COG0653 321 TGRLMPGRRYSDGLHQAIEAKEGVKIQNENQTLASITFQNYFRMY 365
|
|
| PRK12904 |
PRK12904 |
preprotein translocase subunit SecA; Reviewed |
1-364 |
0e+00 |
|
preprotein translocase subunit SecA; Reviewed
Pssm-ID: 237259 [Multi-domain] Cd Length: 830 Bit Score: 751.53 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 1 MLGILNKMF-DPTKRTLNRYEKIANDIDAIRGDYENLSDDALKHKTIEFKERLEKGATTDDLLVEAFAVVREASRRVTGM 79
Cdd:PRK12904 1 MLGLLKKIFgSRNDRELKRLRKIVDKINALEPEMEKLSDEELKAKTAEFKERLAKGETLDDLLPEAFAVVREASKRVLGM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 80 FPFKVQLMGGVALHDGNIAEMKTGEGKTLTSTLPVYLNALTGKGVHIVTVNEYLASRDAEQMGKIFEFLGLTVGLNLNSM 159
Cdd:PRK12904 81 RHFDVQLIGGMVLHEGKIAEMKTGEGKTLVATLPAYLNALTGKGVHVVTVNDYLAKRDAEWMGPLYEFLGLSVGVILSGM 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 160 SKDEKREAYAADITYSTNNELGFDYLRDNMVLYKEQMVQRPLHFAVIDEVDSILIDEARTPLIISGQAAKSTKLYVQANA 239
Cdd:PRK12904 161 SPEERREAYAADITYGTNNEFGFDYLRDNMVFSLEERVQRGLNYAIVDEVDSILIDEARTPLIISGPAEDSSELYKRANK 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 240 FVRTLKAEKDYTYDIKTKAVQLTEEGMTKAEKAFGIDNLFDVKHVALNHHINQALKAHVAMQKDVDYVVEDGQVVIVDSF 319
Cdd:PRK12904 241 IVPTLEKEGDYTVDEKSRTVGLTEEGIEKAEKLLGIENLYDPENIALVHHLNQALRAHELFKRDVDYIVKDGEVVIVDEF 320
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 48980 320 TGRLMKGRRYSEGLHQAIEAKEGLEIQNESMTLATITFQNYFRMY 364
Cdd:PRK12904 321 TGRLMPGRRYSDGLHQAIEAKEGVKIQNENQTLASITFQNYFRMY 365
|
|
| SecA_DEAD |
smart00957 |
SecA DEAD-like domain; SecA protein binds to the plasma membrane where it interacts with ... |
5-364 |
0e+00 |
|
SecA DEAD-like domain; SecA protein binds to the plasma membrane where it interacts with proOmpA to support translocation of proOmpA through the membrane. SecA protein achieves this translocation, in association with SecY protein, in an ATP dependent manner. This domain represents the N-terminal ATP-dependent helicase domain, which is related to the.
Pssm-ID: 214937 [Multi-domain] Cd Length: 380 Bit Score: 694.55 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 5 LNKMF-DPTKRTLNRYEKIANDIDAIRGDYENLSDDALKHKTIEFKERLEKGATTDDLLVEAFAVVREASRRVTGMFPFK 83
Cdd:smart00957 1 LKKLFgSKNDRELKRLRKIVDQINALEPEMEALSDEELRAKTAEFKERLAEGESLDDLLPEAFAVVREAAKRVLGMRHFD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 84 VQLMGGVALHDGNIAEMKTGEGKTLTSTLPVYLNALTGKGVHIVTVNEYLASRDAEQMGKIFEFLGLTVGLNLNSMSKDE 163
Cdd:smart00957 81 VQLIGGIVLHEGKIAEMKTGEGKTLVATLPAYLNALTGKGVHVVTVNDYLAKRDAEWMGPLYEFLGLTVGVIVSGMSPEE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 164 KREAYAADITYSTNNELGFDYLRDNMVLYKEQMVQRPLHFAVIDEVDSILIDEARTPLIISGQAAK-STKLYVQANAFVR 242
Cdd:smart00957 161 RRAAYAADITYGTNNEFGFDYLRDNMAFSKEDKVQRGLNYAIVDEVDSILIDEARTPLIISGPAEDeSSDLYHRADKFVP 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 243 TLKAEKDYTYDIKTKAVQLTEEGMTKAEKAFGIDNLFDVKHVALNHHINQALKAHVAMQKDVDYVVEDGQVVIVDSFTGR 322
Cdd:smart00957 241 RLKEDEDYTVDEKSRTVELTEEGIEKAEKLLGIDNLYDPENIELLHHVNQALRAHYLFKRDVDYIVRDGEVVIVDEFTGR 320
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 48980 323 LMKGRRYSEGLHQAIEAKEGLEIQNESMTLATITFQNYFRMY 364
Cdd:smart00957 321 VMEGRRYSDGLHQAIEAKEGVEIQEENQTLATITFQNYFRMY 362
|
|
| SecA_DEAD |
pfam07517 |
SecA DEAD-like domain; SecA protein binds to the plasma membrane where it interacts with ... |
5-364 |
0e+00 |
|
SecA DEAD-like domain; SecA protein binds to the plasma membrane where it interacts with proOmpA to support translocation of proOmpA through the membrane. SecA protein achieves this translocation, in association with SecY protein, in an ATP dependent manner. This domain represents the N-terminal ATP-dependent helicase domain, which is related to the pfam00270.
Pssm-ID: 462190 [Multi-domain] Cd Length: 379 Bit Score: 645.70 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 5 LNKMF-DPTKRTLNRYEKIANDIDAIRGDYENLSDDALKHKTIEFKERLEKGATTDDLLVEAFAVVREASRRVTGMFPFK 83
Cdd:pfam07517 1 LKKIFgSPNERDLKRLRKIVDQINALEEELKALSDEELRAKTDELRERLREGESLDDILPEAFALVREAAKRVLGMRHYD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 84 VQLMGGVALHDGNIAEMKTGEGKTLTSTLPVYLNALTGKGVHIVTVNEYLASRDAEQMGKIFEFLGLTVGLNLNSMSKDE 163
Cdd:pfam07517 81 VQLIGGLVLHEGKIAEMKTGEGKTLTATLPAYLNALSGKGVHVVTVNDYLAKRDAEWMGPLYEFLGLTVGVITSDMDPEE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 164 KREAYAADITYSTNNELGFDYLRDNMVLYKEQMVQRPLHFAVIDEVDSILIDEARTPLIISGQAAKSTKLYVQANAFVRT 243
Cdd:pfam07517 161 RRAAYNADITYGTNNELGFDYLRDNMATSKEDKVQRGLNFAIVDEVDSILIDEARTPLIISGPSEDDSELYREADRLVKS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 244 LKAEKDYTYDIKTKAVQLTEEGMTKAEKAFGIDNLFDVKHVALNHHINQALKAHVAMQKDVDYVVEDGQVVIVDSFTGRL 323
Cdd:pfam07517 241 LEEDGDYEIDEKSKNVELTEKGIEKIEKLLGIDNLYDPENVELLHHINQALKAHHLFKRDVDYIVRDGEVVIVDEFTGRV 320
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 48980 324 MKGRRYSEGLHQAIEAKEGLEIQNESMTLATITFQNYFRMY 364
Cdd:pfam07517 321 MPGRRWSDGLHQAIEAKEGVEITPESQTLASITYQNFFRLY 361
|
|
| secA |
TIGR00963 |
preprotein translocase, SecA subunit; The proteins SecA-F and SecY, not all of which are ... |
26-364 |
0e+00 |
|
preprotein translocase, SecA subunit; The proteins SecA-F and SecY, not all of which are necessary, comprise the standard prokaryotic protein translocation apparatus. Other, specialized translocation systems also exist but are not as broadly distributed. This model describes SecA, an essential member of the apparatus. This model excludes SecA2 of the accessory secretory system. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273366 [Multi-domain] Cd Length: 742 Bit Score: 640.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 26 IDAIRGDYENLSDDALKHKTIEFKERLEK-GATTDDLLVEAFAVVREASRRVTGMFPFKVQLMGGVALHDGNIAEMKTGE 104
Cdd:TIGR00963 1 INALEEDYEKLSDEELRNKTNEFKDRLAKqGETLDDLLPEAFAVVREASKRVLGMRPFDVQLIGGIALHKGKIAEMKTGE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 105 GKTLTSTLPVYLNALTGKGVHIVTVNEYLASRDAEQMGKIFEFLGLTVGLNLNSMSKDEKREAYAADITYSTNNELGFDY 184
Cdd:TIGR00963 81 GKTLTATLPAYLNALTGKGVHVVTVNDYLAQRDAEWMGQVYRFLGLSVGLILSGMSPEERREAYACDITYGTNNELGFDY 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 185 LRDNMVLYKEQMVQRPLHFAVIDEVDSILIDEARTPLIISGQAAKSTKLYVQANAFVRTLKAEKDYTYDIKTKAVQLTEE 264
Cdd:TIGR00963 161 LRDNMAHSKEEKVQRPFHFAIIDEVDSILIDEARTPLIISGPAEKSTELYVQANKFAKALEKEVDYEVDEKNRAVLLTEQ 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 265 GMTKAEKAFGIDNLFDVKHVALNHHINQALKAHVAMQKDVDYVVEDGQVVIVDSFTGRLMKGRRYSEGLHQAIEAKEGLE 344
Cdd:TIGR00963 241 GMKKAEDLLGVDNLYDLENSPLIHYINNALKAKELFQKDVDYIVRDGEVVIVDEFTGRIMEGRRWSDGLHQAIEAKEGVE 320
|
330 340
....*....|....*....|
gi 48980 345 IQNESMTLATITFQNYFRMY 364
Cdd:TIGR00963 321 IQNENQTLATITYQNFFRLY 340
|
|
| DEXDc_SecA |
cd17928 |
DEXD-box helicase domain of SecA; SecA is a part of the Sec translocase that transports the ... |
40-231 |
4.56e-128 |
|
DEXD-box helicase domain of SecA; SecA is a part of the Sec translocase that transports the vast majority of bacterial and ER-exported proteins. SecA binds both the signal sequence and the mature domain of the preprotein emerging from the ribosome. SecA belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350686 [Multi-domain] Cd Length: 230 Bit Score: 366.47 E-value: 4.56e-128
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 40 ALKHKTIEFKERLEKGATTDDLLVEAFAVVREASRRVTGMFPFKVQLMGGVALHDGNIAEMKTGEGKTLTSTLPVYLNAL 119
Cdd:cd17928 1 ELRAKTDELRERLAKGETLDDLLPEAFALVREAARRVLGMRPFDVQLIGGLVLHEGKIAEMKTGEGKTLTATLPAYLNAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 120 TGKGVHIVTVNEYLASRDAEQMGKIFEFLGLTVGLNLNSMSKDEKREAYAADITYSTNNELGFDYLRDNMVLYKEQMVQR 199
Cdd:cd17928 81 TGKGVHVVTVNDYLARRDAEWMGPLYEFLGLTVGVILSDMSPDERREAYAADITYGTNNELGFDYLRDNMVTSKEDLVQR 160
|
170 180 190
....*....|....*....|....*....|..
gi 48980 200 PLHFAVIDEVDSILIDEARTPLIISGQAAKST 231
Cdd:cd17928 161 GLNFAIVDEVDSILIDEARTPLIISGTLATIT 192
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| SecA |
COG0653 |
Preprotein translocase subunit SecA (ATPase, RNA helicase) [Intracellular trafficking, ... |
1-364 |
0e+00 |
|
Preprotein translocase subunit SecA (ATPase, RNA helicase) [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440418 [Multi-domain] Cd Length: 876 Bit Score: 763.03 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 1 MLGILNKMF-DPTKRTLNRYEKIANDIDAIRGDYENLSDDALKHKTIEFKERLEKGATTDDLLVEAFAVVREASRRVTGM 79
Cdd:COG0653 1 MGKLLKKIFgSRNDRELKRLRKIVDKINALEPEMEALSDEELRAKTDEFKERLANGETLDDLLPEAFAVVREASKRVLGM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 80 FPFKVQLMGGVALHDGNIAEMKTGEGKTLTSTLPVYLNALTGKGVHIVTVNEYLASRDAEQMGKIFEFLGLTVGLNLNSM 159
Cdd:COG0653 81 RHFDVQLIGGIVLHQGKIAEMKTGEGKTLVATLPAYLNALTGKGVHVVTVNDYLAKRDAEWMGRLYRFLGLSVGVIVHGM 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 160 SKDEKREAYAADITYSTNNELGFDYLRDNMVLYKEQMVQRPLHFAVIDEVDSILIDEARTPLIISGQAAKSTKLYVQANA 239
Cdd:COG0653 161 DPEERRAAYAADITYGTNNEFGFDYLRDNMVFSLEDMVQRGLNYAIVDEVDSILIDEARTPLIISGPAEDSTDLYYRINK 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 240 FVRTLKAEKDYTYDIKTKAVQLTEEGMTKAEKAFGIDNLFDVKHVALNHHINQALKAHVAMQKDVDYVVEDGQVVIVDSF 319
Cdd:COG0653 241 LVPRLKRDGDYTVDEKARTVTLTEEGIEKVEKLLGIDNLYDPENIELVHHLNQALRAHALFKRDVDYIVKDGEVVIVDEF 320
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 48980 320 TGRLMKGRRYSEGLHQAIEAKEGLEIQNESMTLATITFQNYFRMY 364
Cdd:COG0653 321 TGRLMPGRRYSDGLHQAIEAKEGVKIQNENQTLASITFQNYFRMY 365
|
|
| PRK12904 |
PRK12904 |
preprotein translocase subunit SecA; Reviewed |
1-364 |
0e+00 |
|
preprotein translocase subunit SecA; Reviewed
Pssm-ID: 237259 [Multi-domain] Cd Length: 830 Bit Score: 751.53 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 1 MLGILNKMF-DPTKRTLNRYEKIANDIDAIRGDYENLSDDALKHKTIEFKERLEKGATTDDLLVEAFAVVREASRRVTGM 79
Cdd:PRK12904 1 MLGLLKKIFgSRNDRELKRLRKIVDKINALEPEMEKLSDEELKAKTAEFKERLAKGETLDDLLPEAFAVVREASKRVLGM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 80 FPFKVQLMGGVALHDGNIAEMKTGEGKTLTSTLPVYLNALTGKGVHIVTVNEYLASRDAEQMGKIFEFLGLTVGLNLNSM 159
Cdd:PRK12904 81 RHFDVQLIGGMVLHEGKIAEMKTGEGKTLVATLPAYLNALTGKGVHVVTVNDYLAKRDAEWMGPLYEFLGLSVGVILSGM 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 160 SKDEKREAYAADITYSTNNELGFDYLRDNMVLYKEQMVQRPLHFAVIDEVDSILIDEARTPLIISGQAAKSTKLYVQANA 239
Cdd:PRK12904 161 SPEERREAYAADITYGTNNEFGFDYLRDNMVFSLEERVQRGLNYAIVDEVDSILIDEARTPLIISGPAEDSSELYKRANK 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 240 FVRTLKAEKDYTYDIKTKAVQLTEEGMTKAEKAFGIDNLFDVKHVALNHHINQALKAHVAMQKDVDYVVEDGQVVIVDSF 319
Cdd:PRK12904 241 IVPTLEKEGDYTVDEKSRTVGLTEEGIEKAEKLLGIENLYDPENIALVHHLNQALRAHELFKRDVDYIVKDGEVVIVDEF 320
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 48980 320 TGRLMKGRRYSEGLHQAIEAKEGLEIQNESMTLATITFQNYFRMY 364
Cdd:PRK12904 321 TGRLMPGRRYSDGLHQAIEAKEGVKIQNENQTLASITFQNYFRMY 365
|
|
| SecA_DEAD |
smart00957 |
SecA DEAD-like domain; SecA protein binds to the plasma membrane where it interacts with ... |
5-364 |
0e+00 |
|
SecA DEAD-like domain; SecA protein binds to the plasma membrane where it interacts with proOmpA to support translocation of proOmpA through the membrane. SecA protein achieves this translocation, in association with SecY protein, in an ATP dependent manner. This domain represents the N-terminal ATP-dependent helicase domain, which is related to the.
Pssm-ID: 214937 [Multi-domain] Cd Length: 380 Bit Score: 694.55 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 5 LNKMF-DPTKRTLNRYEKIANDIDAIRGDYENLSDDALKHKTIEFKERLEKGATTDDLLVEAFAVVREASRRVTGMFPFK 83
Cdd:smart00957 1 LKKLFgSKNDRELKRLRKIVDQINALEPEMEALSDEELRAKTAEFKERLAEGESLDDLLPEAFAVVREAAKRVLGMRHFD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 84 VQLMGGVALHDGNIAEMKTGEGKTLTSTLPVYLNALTGKGVHIVTVNEYLASRDAEQMGKIFEFLGLTVGLNLNSMSKDE 163
Cdd:smart00957 81 VQLIGGIVLHEGKIAEMKTGEGKTLVATLPAYLNALTGKGVHVVTVNDYLAKRDAEWMGPLYEFLGLTVGVIVSGMSPEE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 164 KREAYAADITYSTNNELGFDYLRDNMVLYKEQMVQRPLHFAVIDEVDSILIDEARTPLIISGQAAK-STKLYVQANAFVR 242
Cdd:smart00957 161 RRAAYAADITYGTNNEFGFDYLRDNMAFSKEDKVQRGLNYAIVDEVDSILIDEARTPLIISGPAEDeSSDLYHRADKFVP 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 243 TLKAEKDYTYDIKTKAVQLTEEGMTKAEKAFGIDNLFDVKHVALNHHINQALKAHVAMQKDVDYVVEDGQVVIVDSFTGR 322
Cdd:smart00957 241 RLKEDEDYTVDEKSRTVELTEEGIEKAEKLLGIDNLYDPENIELLHHVNQALRAHYLFKRDVDYIVRDGEVVIVDEFTGR 320
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 48980 323 LMKGRRYSEGLHQAIEAKEGLEIQNESMTLATITFQNYFRMY 364
Cdd:smart00957 321 VMEGRRYSDGLHQAIEAKEGVEIQEENQTLATITFQNYFRMY 362
|
|
| SecA_DEAD |
pfam07517 |
SecA DEAD-like domain; SecA protein binds to the plasma membrane where it interacts with ... |
5-364 |
0e+00 |
|
SecA DEAD-like domain; SecA protein binds to the plasma membrane where it interacts with proOmpA to support translocation of proOmpA through the membrane. SecA protein achieves this translocation, in association with SecY protein, in an ATP dependent manner. This domain represents the N-terminal ATP-dependent helicase domain, which is related to the pfam00270.
Pssm-ID: 462190 [Multi-domain] Cd Length: 379 Bit Score: 645.70 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 5 LNKMF-DPTKRTLNRYEKIANDIDAIRGDYENLSDDALKHKTIEFKERLEKGATTDDLLVEAFAVVREASRRVTGMFPFK 83
Cdd:pfam07517 1 LKKIFgSPNERDLKRLRKIVDQINALEEELKALSDEELRAKTDELRERLREGESLDDILPEAFALVREAAKRVLGMRHYD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 84 VQLMGGVALHDGNIAEMKTGEGKTLTSTLPVYLNALTGKGVHIVTVNEYLASRDAEQMGKIFEFLGLTVGLNLNSMSKDE 163
Cdd:pfam07517 81 VQLIGGLVLHEGKIAEMKTGEGKTLTATLPAYLNALSGKGVHVVTVNDYLAKRDAEWMGPLYEFLGLTVGVITSDMDPEE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 164 KREAYAADITYSTNNELGFDYLRDNMVLYKEQMVQRPLHFAVIDEVDSILIDEARTPLIISGQAAKSTKLYVQANAFVRT 243
Cdd:pfam07517 161 RRAAYNADITYGTNNELGFDYLRDNMATSKEDKVQRGLNFAIVDEVDSILIDEARTPLIISGPSEDDSELYREADRLVKS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 244 LKAEKDYTYDIKTKAVQLTEEGMTKAEKAFGIDNLFDVKHVALNHHINQALKAHVAMQKDVDYVVEDGQVVIVDSFTGRL 323
Cdd:pfam07517 241 LEEDGDYEIDEKSKNVELTEKGIEKIEKLLGIDNLYDPENVELLHHINQALKAHHLFKRDVDYIVRDGEVVIVDEFTGRV 320
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 48980 324 MKGRRYSEGLHQAIEAKEGLEIQNESMTLATITFQNYFRMY 364
Cdd:pfam07517 321 MPGRRWSDGLHQAIEAKEGVEITPESQTLASITYQNFFRLY 361
|
|
| secA |
TIGR00963 |
preprotein translocase, SecA subunit; The proteins SecA-F and SecY, not all of which are ... |
26-364 |
0e+00 |
|
preprotein translocase, SecA subunit; The proteins SecA-F and SecY, not all of which are necessary, comprise the standard prokaryotic protein translocation apparatus. Other, specialized translocation systems also exist but are not as broadly distributed. This model describes SecA, an essential member of the apparatus. This model excludes SecA2 of the accessory secretory system. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273366 [Multi-domain] Cd Length: 742 Bit Score: 640.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 26 IDAIRGDYENLSDDALKHKTIEFKERLEK-GATTDDLLVEAFAVVREASRRVTGMFPFKVQLMGGVALHDGNIAEMKTGE 104
Cdd:TIGR00963 1 INALEEDYEKLSDEELRNKTNEFKDRLAKqGETLDDLLPEAFAVVREASKRVLGMRPFDVQLIGGIALHKGKIAEMKTGE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 105 GKTLTSTLPVYLNALTGKGVHIVTVNEYLASRDAEQMGKIFEFLGLTVGLNLNSMSKDEKREAYAADITYSTNNELGFDY 184
Cdd:TIGR00963 81 GKTLTATLPAYLNALTGKGVHVVTVNDYLAQRDAEWMGQVYRFLGLSVGLILSGMSPEERREAYACDITYGTNNELGFDY 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 185 LRDNMVLYKEQMVQRPLHFAVIDEVDSILIDEARTPLIISGQAAKSTKLYVQANAFVRTLKAEKDYTYDIKTKAVQLTEE 264
Cdd:TIGR00963 161 LRDNMAHSKEEKVQRPFHFAIIDEVDSILIDEARTPLIISGPAEKSTELYVQANKFAKALEKEVDYEVDEKNRAVLLTEQ 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 265 GMTKAEKAFGIDNLFDVKHVALNHHINQALKAHVAMQKDVDYVVEDGQVVIVDSFTGRLMKGRRYSEGLHQAIEAKEGLE 344
Cdd:TIGR00963 241 GMKKAEDLLGVDNLYDLENSPLIHYINNALKAKELFQKDVDYIVRDGEVVIVDEFTGRIMEGRRWSDGLHQAIEAKEGVE 320
|
330 340
....*....|....*....|
gi 48980 345 IQNESMTLATITFQNYFRMY 364
Cdd:TIGR00963 321 IQNENQTLATITYQNFFRLY 340
|
|
| secA |
PRK12906 |
preprotein translocase subunit SecA; Reviewed |
1-364 |
0e+00 |
|
preprotein translocase subunit SecA; Reviewed
Pssm-ID: 237260 [Multi-domain] Cd Length: 796 Bit Score: 622.11 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 1 MLGILNKMFDPTKRTLNRYEKIANDIDAIRGDYENLSDDALKHKTIEFKERLEKGATTDDLLVEAFAVVREASRRVTGMF 80
Cdd:PRK12906 1 MANILKKWFDNDKRELKRLEKIADKVNALEDEYEKLSDEQLQAKTPEFRDRIKDGESLDDLLPEAFAVAREGAKRVLGLR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 81 PFKVQLMGGVALHDGNIAEMKTGEGKTLTSTLPVYLNALTGKGVHIVTVNEYLASRDAEQMGKIFEFLGLTVGLNLNSMS 160
Cdd:PRK12906 81 PFDVQIIGGIVLHEGNIAEMKTGEGKTLTATLPVYLNALTGKGVHVVTVNEYLSSRDATEMGELYRWLGLTVGLNLNSMS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 161 KDEKREAYAADITYSTNNELGFDYLRDNMVLYKEQMVQRPLHFAVIDEVDSILIDEARTPLIISGQAAKSTKLYVQANAF 240
Cdd:PRK12906 161 PDEKRAAYNCDITYSTNSELGFDYLRDNMVVYKEQMVQRPLNYAIVDEVDSILIDEARTPLIISGQAEKATDLYIRADRF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 241 VRTLKAEK-----------DYTYDIKTKAVQLTEEGMTKAEKAFGIDNLFDVKHVALNHHINQALKAHVAMQKDVDYVVE 309
Cdd:PRK12906 241 VKTLIKDEaedgdddedtgDYKIDEKTKTISLTEQGIRKAEKLFGLDNLYDSENTALAHHIDQALRANYIMLKDIDYVVQ 320
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 48980 310 DGQVVIVDSFTGRLMKGRRYSEGLHQAIEAKEGLEIQNESMTLATITFQNYFRMY 364
Cdd:PRK12906 321 DGEVLIVDEFTGRVMEGRRYSDGLHQAIEAKEGVKIQEENQTLATITYQNFFRMY 375
|
|
| PRK09200 |
PRK09200 |
preprotein translocase subunit SecA; Reviewed |
6-364 |
0e+00 |
|
preprotein translocase subunit SecA; Reviewed
Pssm-ID: 236408 [Multi-domain] Cd Length: 790 Bit Score: 576.12 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 6 NKMFDPTKRTLNRYEKIANDIDAIRGDYENLSDDALKHKTIEFKERLEKGATTDDLLVEAFAVVREASRRVTGMFPFKVQ 85
Cdd:PRK09200 4 KLLGDIDKRRLKKYRKIVKQINKLEGKMSSLSDEELRQKTIEFKERLASGKTLDDILPEAFAVVREAAKRVLGMRPYDVQ 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 86 LMGGVALHDGNIAEMKTGEGKTLTSTLPVYLNALTGKGVHIVTVNEYLASRDAEQMGKIFEFLGLTVGLNLNSMSK-DEK 164
Cdd:PRK09200 84 LIGALVLHEGNIAEMQTGEGKTLTATMPLYLNALEGKGVHLITVNDYLAKRDAEEMGQVYEFLGLTVGLNFSDIDDaSEK 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 165 REAYAADITYSTNNELGFDYLRDNMVLYKEQMVQRPLHFAVIDEVDSILIDEARTPLIISGQAAKSTKLYVQANAFVRTL 244
Cdd:PRK09200 164 KAIYEADIIYTTNSELGFDYLRDNLADSKEDKVQRPLNYAIIDEIDSILLDEAQTPLIISGKPRVQSNLYHIAAKFVKTL 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 245 KAEKDYTYDIKTKAVQLTEEGMTKAEKAFGIDNLFDVKHVALNHHINQALKAHVAMQKDVDYVVEDGQVVIVDSFTGRLM 324
Cdd:PRK09200 244 EEDVDYEFDEEKKEVWLTDQGIEKAESYFGIDNLYSLEHQVLYRHIILALRAHVLFKRDVDYIVYDGEIVLVDRFTGRVL 323
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 48980 325 KGRRYSEGLHQAIEAKEGLEIQNESMTLATITFQNYFRMY 364
Cdd:PRK09200 324 PGRKLQDGLHQAIEAKEGVEITEENRTMASITIQNLFRMF 363
|
|
| SecA2_Bac_anthr |
TIGR04397 |
accessory Sec system translocase SecA2, Bacillus type; Members of this family always occur in ... |
10-364 |
0e+00 |
|
accessory Sec system translocase SecA2, Bacillus type; Members of this family always occur in genomes with the preprotein translocase SecA (TIGR00963) and closely resemble it, hence the designation SecA2. However, this appears to mark a different type of accessory Sec system SecA2 (TIGR03714) from the serine-rich glycoprotein type found in Staphylococcus and Streptococcus, and the actinobacterial SecA2 (TIGR04221). This type occurs in species including Bacillus anthracis, Geobacillus thermoglucosidasius, Solibacillus silvestris, etc. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 275190 [Multi-domain] Cd Length: 774 Bit Score: 556.65 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 10 DPTKRTLNRYEKIANDIDAIRGDYENLSDDALKHKTIEFKERLEKGATTDDLLVEAFAVVREASRRVTGMFPFKVQLMGG 89
Cdd:TIGR04397 7 DSSARELKRYEKLVAQINELEPKMEKLSDEELRQKTITFKERLEDGKTVDDIKVEAFAVVREASKRVLGMRHYDVQLIGG 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 90 VALHDGNIAEMKTGEGKTLTSTLPVYLNALTGKGVHIVTVNEYLASRDAEQMGKIFEFLGLTVGLNLNSMSKDEKREAYA 169
Cdd:TIGR04397 87 LVLLEGNIAEMPTGEGKTLVASLPSYLRALEGKGVHVITVNDYLARRDRELIGQIHEFLGLTVGLNVPMMEASEKKEAYQ 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 170 ADITYSTNNELGFDYLRDNMVLYKEQMVQRPLHFAVIDEVDSILIDEARTPLIISGQAAKSTKLYVQANAFVRTLKAEKD 249
Cdd:TIGR04397 167 ADITYGVGTEFGFDYLRDNMVYSLSDKVQRPYHFAIIDEIDSVLIDEAKTPLIIAGKTGSSSELHYICARIIKSFEETED 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 250 YTYDIKTKAVQLTEEGMTKAEKAFGIDNLFDVKHVALNHHINQALKAHVAMQKDVDYVVEDGQVVIVDSFTGRLMKGRRY 329
Cdd:TIGR04397 247 YEYDPETKAASLTEEGITKIERAFGIDNLYDLEHQTLYHYLIQALRAHVLFKRDVDYIVKDGKIELVDMFTGRIMEGRSL 326
|
330 340 350
....*....|....*....|....*....|....*
gi 48980 330 SEGLHQAIEAKEGLEIQNESMTLATITFQNYFRMY 364
Cdd:TIGR04397 327 SDGLHQAIEAKEGLEITEENKTQASITIQNYFRMY 361
|
|
| secA |
PRK12903 |
preprotein translocase subunit SecA; Reviewed |
7-364 |
0e+00 |
|
preprotein translocase subunit SecA; Reviewed
Pssm-ID: 237258 [Multi-domain] Cd Length: 925 Bit Score: 548.12 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 7 KMFDPTKRTLNRYEKIANDIDAIRGDYENLSDDALKHKTIEFKERLEKGATTDDLLVEAFAVVREASRRVTGMFPFKVQL 86
Cdd:PRK12903 5 KLFFFKSTEMRIAEKILKQINDLEPYYRNLTDEELANKTNEFKDRLKNGETLEDIRVEAFAVAREATKRVLGKRPYDVQI 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 87 MGGVALHDGNIAEMKTGEGKTLTSTLPVYLNALTGKGVHIVTVNEYLASRDAEQMGKIFEFLGLTVGLNLNSMSKDEKRE 166
Cdd:PRK12903 85 IGGIILDLGSVAEMKTGEGKTITSIAPVYLNALTGKGVIVSTVNEYLAERDAEEMGKVFNFLGLSVGINKANMDPNLKRE 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 167 AYAADITYSTNNELGFDYLRDNMVLYKEQMVQRPLHFAVIDEVDSILIDEARTPLIISGQAAKSTKLYVQANAFVRTLKa 246
Cdd:PRK12903 165 AYACDITYSVHSELGFDYLRDNMVSSKEEKVQRGLNFCLIDEVDSILIDEAKTPLIISGGQSNDSNLYLAADQFVRTLK- 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 247 EKDYTYDIKTKAVQLTEEGMTKAEKAFGIDNLFDVKHVALNHHINQALKAHVAMQKDVDYVVEDGQVVIVDSFTGRLMKG 326
Cdd:PRK12903 244 EDDYKIDEETKAISLTEKGIKKANKFFKLKNLYDIENSELVHRIQNALRAHKVMKEDVEYIVRDGKIELVDQFTGRIMEG 323
|
330 340 350
....*....|....*....|....*....|....*...
gi 48980 327 RRYSEGLHQAIEAKEGLEIQNESMTLATITFQNYFRMY 364
Cdd:PRK12903 324 RSYSEGLQQAIQAKEMVEIEPETKTLATITYQNFFRLF 361
|
|
| secA |
CHL00122 |
preprotein translocase subunit SecA; Validated |
7-364 |
2.66e-174 |
|
preprotein translocase subunit SecA; Validated
Pssm-ID: 214371 [Multi-domain] Cd Length: 870 Bit Score: 506.84 E-value: 2.66e-174
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 7 KMFDPTKRTLNRYEKIANDIDAIRGDYENLSDDALKHKTIEFKERLEKGATTDDLLVEAFAVVREASRRVTGMFPFKVQL 86
Cdd:CHL00122 3 NNLFNNKSKLNKYQTLVNQINLLEEELKNLTDTELRSKTNKLKKRLSNGQNLNKIIPESFALTREASFRTLGLRHFDVQL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 87 MGGVALHDGNIAEMKTGEGKTLTSTLPVYLNALTGKGVHIVTVNEYLASRDAEQMGKIFEFLGLTVGLNLNSMSKDEKRE 166
Cdd:CHL00122 83 IGGLVLNDGKIAEMKTGEGKTLVATLPAYLNALTGKGVHIVTVNDYLAKRDQEWMGQIYRFLGLTVGLIQEGMSSEERKK 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 167 AYAADITYSTNNELGFDYLRDNMVLYKEQMVQRPLHFAVIDEVDSILIDEARTPLIISGQAAKSTKLYVQANAFVRTLKA 246
Cdd:CHL00122 163 NYLKDITYVTNSELGFDYLRDNMALSLSDVVQRPFNYCIIDEVDSILIDEARTPLIISGQSKTNIDKYIVADELAKYLEK 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 247 EKDYTYDIKTKAVQLTEEGMTKAEKAFGIDNLFDVKHVALNHHINqALKAHVAMQKDVDYVVEDGQVVIVDSFTGRLMKG 326
Cdd:CHL00122 243 NVHYEVDEKNKNVILTEQGILFIEKILKIEDLYSANDPWIPYILN-ALKAKELFFKNVHYIVRNNEIIIVDEFTGRIMPG 321
|
330 340 350
....*....|....*....|....*....|....*...
gi 48980 327 RRYSEGLHQAIEAKEGLEIQNESMTLATITFQNYFRMY 364
Cdd:CHL00122 322 RRWSDGLHQAIEAKENLPIRQETETLASITYQNFFLLY 359
|
|
| secA2 |
TIGR03714 |
accessory Sec system translocase SecA2; Members of this protein family are homologous to SecA ... |
16-364 |
9.99e-162 |
|
accessory Sec system translocase SecA2; Members of this protein family are homologous to SecA and part of the accessory Sec system. This system, including both five core proteins for export and a variable number of proteins for glycosylation, operates in certain Gram-positive pathogens for the maturation and delivery of serine-rich glycoproteins such as the cell surface glycoprotein GspB in Streptococcus gordonii. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 163426 [Multi-domain] Cd Length: 762 Bit Score: 471.45 E-value: 9.99e-162
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 16 LNRYEKIANDIDAIRGDYENLSDDALKHKTIEFKERLEKGATTDDLLVEAFAVVREASRRVTGMFPFKVQLMGGVALHDG 95
Cdd:TIGR03714 6 LKKLRKILNKINALKGKMATLSDEELQAKTAEFKNRLVEGESLDDILPEAYAVVREADKRVLGMFPYDVQVLGAIVLHQG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 96 NIAEMKTGEGKTLTSTLPVYLNALTGKGVHIVTVNEYLASRDAEQMGKIFEFLGLTVGLNLNSMSKDE-----KREAYAA 170
Cdd:TIGR03714 86 NIAEMKTGEGKTLTATMPLYLNALTGKGAMLVTTNDYLAKRDAEEMGPVYEWLGLTVSLGVVDDPDEEydaneKRKIYNS 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 171 DITYSTNNELGFDYLRDNMVLYKEQMVQRPLHFAVIDEVDSILIDEARTPLIISGQAAKSTKLYVQANAFVRTLKAEKDY 250
Cdd:TIGR03714 166 DIVYTTNSALGFDYLIDNLASNKEGKFLRPFNYVIVDEVDSVLLDSAQTPLVISGAPRVQSNLYHIADTFVRTLKEDVDY 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 251 TYDIKTKAVQLTEEGMTKAEKAFGIDNLFDVKHVALNHHINQALKAHVAMQKDVDYVVEDGQVVIVDSFTGRLMKGRRYS 330
Cdd:TIGR03714 246 IFKKDKKEVWLTDKGIEKAEQYFKIDNLYSEEYFELVRHINLALRAHYLFKRNKDYVVTNGEVVLLDRITGRLLEGTKLQ 325
|
330 340 350
....*....|....*....|....*....|....
gi 48980 331 EGLHQAIEAKEGLEIQNESMTLATITFQNYFRMY 364
Cdd:TIGR03714 326 SGIHQAIEAKEHVELSKETRAMASITYQNLFKMF 359
|
|
| secA |
PRK12898 |
preprotein translocase subunit SecA; Reviewed |
14-364 |
7.14e-136 |
|
preprotein translocase subunit SecA; Reviewed
Pssm-ID: 237253 [Multi-domain] Cd Length: 656 Bit Score: 401.70 E-value: 7.14e-136
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 14 RTLNRYEKIANDIDAIRGDYENLSDDALKHKTIEFKERL-EKGATTDDLLVEAFAVVREASRRVTGMFPFKVQLMGGVAL 92
Cdd:PRK12898 36 RAARRQRLLADRVLAAAEALAGLSEEALRARSLALRARLrARDGFRDALLAEAFALVREASGRVLGQRHFDVQLMGGLAL 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 93 HDGNIAEMKTGEGKTLTSTLPVYLNALTGKGVHIVTVNEYLASRDAEQMGKIFEFLGLTVGLNLNSMSKDEKREAYAADI 172
Cdd:PRK12898 116 LSGRLAEMQTGEGKTLTATLPAGTAALAGLPVHVITVNDYLAERDAELMRPLYEALGLTVGCVVEDQSPDERRAAYGADI 195
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 173 TYSTNNELGFDYLRDNMVLYK-------------------EQMVQRPLHFAVIDEVDSILIDEARTPLIISG--QAAKST 231
Cdd:PRK12898 196 TYCTNKELVFDYLRDRLALGQrasdarlaleslhgrssrsTQLLLRGLHFAIVDEADSVLIDEARTPLIISApaKEADEA 275
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 232 KLYVQANAFVRTLKAEKDYTYDIKTKAVQLTEEGMTKAEKAFGIDNLFDVKHVALNHHINQALKAHVAMQKDVDYVVEDG 311
Cdd:PRK12898 276 EVYRQALELAAQLKEGEDYTIDAAEKRIELTEAGRARIAELAESLPPAWRGAVRREELVRQALSALHLFRRDEHYIVRDG 355
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 48980 312 QVVIVDSFTGRLMKGRRYSEGLHQAIEAKEGLEIQNESMTLATITFQNYFRMY 364
Cdd:PRK12898 356 KVVIVDEFTGRVMPDRSWEDGLHQMIEAKEGCELTDPRETLARITYQRFFRRY 408
|
|
| DEXDc_SecA |
cd17928 |
DEXD-box helicase domain of SecA; SecA is a part of the Sec translocase that transports the ... |
40-231 |
4.56e-128 |
|
DEXD-box helicase domain of SecA; SecA is a part of the Sec translocase that transports the vast majority of bacterial and ER-exported proteins. SecA binds both the signal sequence and the mature domain of the preprotein emerging from the ribosome. SecA belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350686 [Multi-domain] Cd Length: 230 Bit Score: 366.47 E-value: 4.56e-128
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 40 ALKHKTIEFKERLEKGATTDDLLVEAFAVVREASRRVTGMFPFKVQLMGGVALHDGNIAEMKTGEGKTLTSTLPVYLNAL 119
Cdd:cd17928 1 ELRAKTDELRERLAKGETLDDLLPEAFALVREAARRVLGMRPFDVQLIGGLVLHEGKIAEMKTGEGKTLTATLPAYLNAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 120 TGKGVHIVTVNEYLASRDAEQMGKIFEFLGLTVGLNLNSMSKDEKREAYAADITYSTNNELGFDYLRDNMVLYKEQMVQR 199
Cdd:cd17928 81 TGKGVHVVTVNDYLARRDAEWMGPLYEFLGLTVGVILSDMSPDERREAYAADITYGTNNELGFDYLRDNMVTSKEDLVQR 160
|
170 180 190
....*....|....*....|....*....|..
gi 48980 200 PLHFAVIDEVDSILIDEARTPLIISGQAAKST 231
Cdd:cd17928 161 GLNFAIVDEVDSILIDEARTPLIISGTLATIT 192
|
|
| secA |
PRK12901 |
preprotein translocase subunit SecA; Reviewed |
1-364 |
1.96e-119 |
|
preprotein translocase subunit SecA; Reviewed
Pssm-ID: 237256 [Multi-domain] Cd Length: 1112 Bit Score: 370.89 E-value: 1.96e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 1 MLGILNKMF-DPTKRTLNRYEKIANDIDAIRGDYENLSDDALKHKTIEFKER---------------------------- 51
Cdd:PRK12901 1 MNEFLKKLFgDKSERDLKEIQPIVEKIKAEYPELEALSNDELRAKTDEFKQYikeavadidakieelkaeaiesldider 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 52 ---------LEKGATT------DDLLVEAFAVVREASRRVTG-------------------------------------- 78
Cdd:PRK12901 81 ediyaqidkLEKEAYEilekvlDEILPEAFAIVKETARRFAEneeievtatdfdrelaatkdfvtiegdkaiwknhwdag 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 79 -------MFPFKVQLMGGVALHDGNIAEMKTGEGKTLTSTLPVYLNALTGKGVHIVTVNEYLASRDAEQMGKIFEFLGLT 151
Cdd:PRK12901 161 gneitwdMVHYDVQLIGGVVLHQGKIAEMATGEGKTLVATLPVYLNALTGNGVHVVTVNDYLAKRDSEWMGPLYEFHGLS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 152 VG-LNLNSMSKDEKREAYAADITYSTNNELGFDYLRDNMVLYKEQMVQRPLHFAVIDEVDSILIDEARTPLIISGQAAKS 230
Cdd:PRK12901 241 VDcIDKHQPNSEARRKAYNADITYGTNNEFGFDYLRDNMAHSPEDLVQRKHNYAIVDEVDSVLIDDARTPLIISGPVPKG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 231 -TKLYVQ---------------ANAFV---RTLKAEKD------------------------------------------ 249
Cdd:PRK12901 321 dDQEFEElkprverlveaqrklATQFLaeaKKLIAEGDkkegglallrayrglpknkalikflseegikallqktenfym 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 250 ---------------YTYDIKTKAVQLTEEG----------------------MTKAEKAFGIDNL------------FD 280
Cdd:PRK12901 401 qdnnrempevdeelyFVIDEKNNSVELTDKGidyitgndedpdffvlpdigteLAEIENEGGLDEEeeaekkeelfqdYS 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 281 VKHVALnHHINQALKAHVAMQKDVDYVVEDGQVVIVDSFTGRLMKGRRYSEGLHQAIEAKEGLEIQNESMTLATITFQNY 360
Cdd:PRK12901 481 VKSERV-HTLNQLLKAYTLFEKDDEYVVMDGKVKIVDEQTGRIMEGRRYSDGLHQAIEAKENVKIEAATQTFATITLQNY 559
|
....
gi 48980 361 FRMY 364
Cdd:PRK12901 560 FRMY 563
|
|
| SecA_PP_bind |
pfam01043 |
SecA preprotein cross-linking domain; The SecA ATPase is involved in the insertion and ... |
229-338 |
1.55e-64 |
|
SecA preprotein cross-linking domain; The SecA ATPase is involved in the insertion and retraction of preproteins through the plasma membrane. This domain has been found to cross-link to preproteins, thought to indicate a role in preprotein binding. The pre-protein cross-linking domain is comprised of two sub domains that are inserted within the ATPase domain.
Pssm-ID: 460039 [Multi-domain] Cd Length: 110 Bit Score: 200.33 E-value: 1.55e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 229 KSTKLYVQANAFVRTLKAEKDYTYDIKTKAVQLTEEGMTKAEKAFGIDNLFDVKHVALNHHINQALKAHVAMQKDVDYVV 308
Cdd:pfam01043 1 KSTELYRQADKFVKQLKEDEDYEVDEKAKTVELTEEGIEKAEKLLGIDNLYDPENIELVHHINQALKAHHLFKRDVDYIV 80
|
90 100 110
....*....|....*....|....*....|
gi 48980 309 EDGQVVIVDSFTGRLMKGRRYSEGLHQAIE 338
Cdd:pfam01043 81 KDGEVVIVDEFTGRLMPGRRYSDGLHQAIE 110
|
|
| SecA_PP_bind |
smart00958 |
SecA preprotein cross-linking domain; The SecA ATPase is involved in the insertion and ... |
226-338 |
1.92e-62 |
|
SecA preprotein cross-linking domain; The SecA ATPase is involved in the insertion and retraction of preproteins through the plasma membrane. This domain has been found to cross-link to preproteins, thought to indicate a role in preprotein binding. The pre-protein cross-linking domain is comprised of two sub domains that are inserted within the ATPase domain.
Pssm-ID: 214938 [Multi-domain] Cd Length: 114 Bit Score: 194.98 E-value: 1.92e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 226 QAAKSTKLYVQANAFVRTL-KAEKDYTYDIKTKAVQLTEEGMTKAEKAFGIDNLFDVKHVALNHHINQALKAHVAMQKDV 304
Cdd:smart00958 1 PAEDSSELYKRADELVPTLkKDEEDYEVDEKSRQVALTEEGIEKAEKLLGIDNLYDPENIELVHHVNQALRAHKLFKRDV 80
|
90 100 110
....*....|....*....|....*....|....
gi 48980 305 DYVVEDGQVVIVDSFTGRLMKGRRYSEGLHQAIE 338
Cdd:smart00958 81 DYIVRDGEVVIVDEFTGRVMPGRRWSDGLHQAIE 114
|
|
| SF2-N |
cd00046 |
N-terminal DEAD/H-box helicase domain of superfamily 2 helicases; The DEAD/H-like superfamily ... |
97-222 |
3.00e-15 |
|
N-terminal DEAD/H-box helicase domain of superfamily 2 helicases; The DEAD/H-like superfamily 2 helicases comprise a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This N-terminal domain contains the ATP-binding region.
Pssm-ID: 350668 [Multi-domain] Cd Length: 146 Bit Score: 72.05 E-value: 3.00e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 97 IAEMKTGEGKTLTSTLPVYLNALT-GKGVHIVTVNEYLASRDAEQMGKIFeFLGLTVGLnLNSMSKDEKREAYA---ADI 172
Cdd:cd00046 5 LITAPTGSGKTLAALLAALLLLLKkGKKVLVLVPTKALALQTAERLRELF-GPGIRVAV-LVGGSSAEEREKNKlgdADI 82
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 48980 173 TYSTNNELGFDYLRDnmvlykEQMVQRPLHFAVIDEVDSILIDEARTPLI 222
Cdd:cd00046 83 IIATPDMLLNLLLRE------DRLFLKDLKLIIVDEAHALLIDSRGALIL 126
|
|
| DEAD-like_helicase_N |
cd17912 |
N-terminal helicase domain of the DEAD-box helicase superfamily; The DEAD-like helicase ... |
97-137 |
3.35e-07 |
|
N-terminal helicase domain of the DEAD-box helicase superfamily; The DEAD-like helicase superfamily is a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. The N-terminal domain contains the ATP-binding region.
Pssm-ID: 350670 [Multi-domain] Cd Length: 81 Bit Score: 47.51 E-value: 3.35e-07
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 48980 97 IAEMKTGEGKTLTSTLPVYLNALTGKGVHIVTVNEYLASRD 137
Cdd:cd17912 3 LHLGPTGSGKTLVAIQKIASAMSSGKSVLVVTPTKLLAHEI 43
|
|
| DEXDc |
smart00487 |
DEAD-like helicases superfamily; |
80-223 |
1.88e-04 |
|
DEAD-like helicases superfamily;
Pssm-ID: 214692 [Multi-domain] Cd Length: 201 Bit Score: 42.09 E-value: 1.88e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 80 FPFKVQLMGGVALHDGN---IAEMKTGEGKTLTSTLPVYLNALTGKGVHIV----TVNeyLASRDAEQMGKIFEFLGLTV 152
Cdd:smart00487 8 PLRPYQKEAIEALLSGLrdvILAAPTGSGKTLAALLPALEALKRGKGGRVLvlvpTRE--LAEQWAEELKKLGPSLGLKV 85
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 48980 153 GLNLNSMSKDEKREAYA---ADITYSTnnelgFDYLRDNmvLYKEQMVQRPLHFAVIDEVDSILiDEARTPLII 223
Cdd:smart00487 86 VGLYGGDSKREQLRKLEsgkTDILVTT-----PGRLLDL--LENDKLSLSNVDLVILDEAHRLL-DGGFGDQLE 151
|
|
| DEAD |
pfam00270 |
DEAD/DEAH box helicase; Members of this family include the DEAD and DEAH box helicases. ... |
97-213 |
6.29e-04 |
|
DEAD/DEAH box helicase; Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.
Pssm-ID: 425570 [Multi-domain] Cd Length: 165 Bit Score: 39.92 E-value: 6.29e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48980 97 IAEMKTGEGKTLTSTLPVyLNALTGKGVHIVTVneYLA-SRD-AEQMG----KIFEFLGLTVGLNLNSMSKDEKREAYA- 169
Cdd:pfam00270 18 LVQAPTGSGKTLAFLLPA-LEALDKLDNGPQAL--VLApTRElAEQIYeelkKLGKGLGLKVASLLGGDSRKEQLEKLKg 94
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 48980 170 ADITYSTNNELgFDYLRDNMVLYKEQMVqrplhfaVIDEVDSIL 213
Cdd:pfam00270 95 PDILVGTPGRL-LDLLQERKLLKNLKLL-------VLDEAHRLL 130
|
|
| |
