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Conserved domains on  [gi|52545619|emb|CAB70768|]
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hypothetical protein, partial [Homo sapiens]

Protein Classification

DMAC1 family protein( domain architecture ID 10633351)

distal membrane arm assembly complex 1 (DMAC1) family protein is a DUF4536 domain-containing protein similar to human DMAC1, which is required for the assembly of the mitochondrial NADH:ubiquinone oxidoreductase complex (complex I)

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
DUF4536 pfam15055
Domain of unknown function (DUF4536); This domain family is thought to be a transmembrane ...
5-50 1.53e-18

Domain of unknown function (DUF4536); This domain family is thought to be a transmembrane helix. It is found in eukaryotes, and is approximately 50 amino acids in length. In humans, it is located in the chromosomal position, C9orf123. The family contains the uncharacterized Sch. pombe protein TAM6 which is found in the mitochondrion.


:

Pssm-ID: 464474  Cd Length: 47  Bit Score: 70.80  E-value: 1.53e-18
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 52545619    5 CWSCRVLSGLGLMGAGGYVYWVARKPMKMGYPPSPWTITQMVIGLS 50
Cdd:pfam15055  2 CWSCRLVSGSGLIGAGAYVYVQARRRMKLGGPPGMGTIAQMAFALG 47
 
Name Accession Description Interval E-value
DUF4536 pfam15055
Domain of unknown function (DUF4536); This domain family is thought to be a transmembrane ...
5-50 1.53e-18

Domain of unknown function (DUF4536); This domain family is thought to be a transmembrane helix. It is found in eukaryotes, and is approximately 50 amino acids in length. In humans, it is located in the chromosomal position, C9orf123. The family contains the uncharacterized Sch. pombe protein TAM6 which is found in the mitochondrion.


Pssm-ID: 464474  Cd Length: 47  Bit Score: 70.80  E-value: 1.53e-18
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 52545619    5 CWSCRVLSGLGLMGAGGYVYWVARKPMKMGYPPSPWTITQMVIGLS 50
Cdd:pfam15055  2 CWSCRLVSGSGLIGAGAYVYVQARRRMKLGGPPGMGTIAQMAFALG 47
 
Name Accession Description Interval E-value
DUF4536 pfam15055
Domain of unknown function (DUF4536); This domain family is thought to be a transmembrane ...
5-50 1.53e-18

Domain of unknown function (DUF4536); This domain family is thought to be a transmembrane helix. It is found in eukaryotes, and is approximately 50 amino acids in length. In humans, it is located in the chromosomal position, C9orf123. The family contains the uncharacterized Sch. pombe protein TAM6 which is found in the mitochondrion.


Pssm-ID: 464474  Cd Length: 47  Bit Score: 70.80  E-value: 1.53e-18
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 52545619    5 CWSCRVLSGLGLMGAGGYVYWVARKPMKMGYPPSPWTITQMVIGLS 50
Cdd:pfam15055  2 CWSCRLVSGSGLIGAGAYVYVQARRRMKLGGPPGMGTIAQMAFALG 47
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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