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Conserved domains on  [gi|979879409|emb|CUS96687|]
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Peptidase S46 [Candidatus Kryptonium thompsonii]

Protein Classification

S46 family peptidase( domain architecture ID 12106229)

S46 family peptidase is a serine protease similar to Capnocytophaga gingivalis dipeptidyl-peptidase 7 and Asp/Glu-specific dipeptidyl-peptidase, which catalyze the removal of dipeptides from the N-terminus of oligopeptides

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Peptidase_S46 pfam10459
Peptidase S46; Dipeptidyl-peptidase 7 (DPP-7) is the best characterized member of this family. ...
 49-718 0e+00

Peptidase S46; Dipeptidyl-peptidase 7 (DPP-7) is the best characterized member of this family. It is a serine peptidase that is located on the cell surface and is predicted to have two N-terminal transmembrane domains.


:

Pssm-ID: 431297  Cd Length: 695  Bit Score: 640.08  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979879409   49 MWTFDYPPI--DYFKKtYNFTPTSDWFEKARLSALR-----LPGCSASFVSEDGLVMTNHHCARGALDAVNREGENLPET 121
Cdd:pfam10459   4 MWTPQQLPEqaDKLKA-LGLEIDAEWLYNLRRSSKDavvrfGGGCTGSFVSPDGLVLTNHHCAYGAIQQHSSVEHDYLKD 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979879409  122 GFYAATLEEERKIPNHYVDQLIYIGDVTDEIQKAFEEGKTDAERVANRDKKIREIQqryyeefKKSNPEDSIVASVVTFY 201
Cdd:pfam10459  83 GFLAKSRAEELPAPGLRVTVLVRITDVTDRVRAALKAGTDGEERSKAIEARLKALA-------KECEKEDGLRCEVVAFY 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979879409  202 NGGKYSIYVYKRYTDVRLVYAPETIVAYFGGDPDNFTYPRYDLDVAFFRVY-----------KDGKPLKTKYYFPFSKTG 270
Cdd:pfam10459 156 GGNEYYLYKYREYKDVRLVFAPPSSIGKFGGDTDNWMWPRHTGDFSFFRAYagkdgkpadysKDNVPYKPKHFLKISLKG 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979879409  271 VKEGDPVFVIGNPGRTNRLLTVSQLEFFRDVSYPYTLSVLDNLVRIYSDFIAKHPDKKLKYQTRLFSFSNSQKAYAGRLA 350
Cdd:pfam10459 236 VKEGDFVFVAGYPGSTSRYLTSAEVEERRDWVNPARIDRRGERQALLEREMLKDPEIRIKYASKLAGSANYWKNLIGMLE 315

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979879409  351 GLRDAYLMARKRDFEKNFKNSVLNNPNLKAKYGNLWDEIAKYQVEKTKLFHELQAYSFTGPSRSVYFRIANDLVEYAEQM 430
Cdd:pfam10459 316 GLRDLDVLAKKQAREAALRAWLRKDPARRKKYGDALDELDALQAERRDLARRYYYFEEAFSGGSELLSAARTLVRLAKER 395

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979879409  431 KLPEERRADAYKGERLKATKVRIFPQE--IETELEKAILIYQLN-YMKSVFGEKNQAFNELLKGK---SPEEVVDNLLNV 504
Cdd:pfam10459 396 EKPDAEREPGYQERALPTLKKSLERIDadYDPEVDKAVLAAMLEeYRELLGADRLPAVDKLLGKEfkgSPDAYADRLYAG 475

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979879409  505 TILSDKEKVTALLEGNPDDILKSNDPFISFVVKTRQRALEVREKYNSVSAKESAKLQLLGRAIFDVYG-TSIPPDATFTL 583
Cdd:pfam10459 476 SKLTDPANRLALLEGGKAAVEASKDPMIALAVALADARRALEKAEKELDGAIERARPLYAKARLAMYGsTPVYPDANSTL 555

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979879409  584 RIADGVVKSYEYNGTI-APPITTFYGLYDRHYsfktTNRTDWELPERWKNLPSTFD--------LSTPLNFVATNDIIGG 654
Cdd:pfam10459 556 RLTYGQVKGYSPRDGVyYPPFTTLDGVFEKED----TGEEPFDVPEKLLDAIEAKDfgryaaenGSVPVNFLSTNDITGG 631

                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 979879409  655 NSGSPVVNMNLEVVGLIFDGNIESLPGDFIYVDEKNRAVAVDVRGIVEALRHIYNADRLVDELE 718
Cdd:pfam10459 632 NSGSPVLNGKGELVGLAFDGNWESLSGDIGFDPDLQRAVAVDIRYILWALDKVYGADHLIDELT 695
 
Name Accession Description Interval E-value
Peptidase_S46 pfam10459
Peptidase S46; Dipeptidyl-peptidase 7 (DPP-7) is the best characterized member of this family. ...
 49-718 0e+00

Peptidase S46; Dipeptidyl-peptidase 7 (DPP-7) is the best characterized member of this family. It is a serine peptidase that is located on the cell surface and is predicted to have two N-terminal transmembrane domains.


Pssm-ID: 431297  Cd Length: 695  Bit Score: 640.08  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979879409   49 MWTFDYPPI--DYFKKtYNFTPTSDWFEKARLSALR-----LPGCSASFVSEDGLVMTNHHCARGALDAVNREGENLPET 121
Cdd:pfam10459   4 MWTPQQLPEqaDKLKA-LGLEIDAEWLYNLRRSSKDavvrfGGGCTGSFVSPDGLVLTNHHCAYGAIQQHSSVEHDYLKD 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979879409  122 GFYAATLEEERKIPNHYVDQLIYIGDVTDEIQKAFEEGKTDAERVANRDKKIREIQqryyeefKKSNPEDSIVASVVTFY 201
Cdd:pfam10459  83 GFLAKSRAEELPAPGLRVTVLVRITDVTDRVRAALKAGTDGEERSKAIEARLKALA-------KECEKEDGLRCEVVAFY 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979879409  202 NGGKYSIYVYKRYTDVRLVYAPETIVAYFGGDPDNFTYPRYDLDVAFFRVY-----------KDGKPLKTKYYFPFSKTG 270
Cdd:pfam10459 156 GGNEYYLYKYREYKDVRLVFAPPSSIGKFGGDTDNWMWPRHTGDFSFFRAYagkdgkpadysKDNVPYKPKHFLKISLKG 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979879409  271 VKEGDPVFVIGNPGRTNRLLTVSQLEFFRDVSYPYTLSVLDNLVRIYSDFIAKHPDKKLKYQTRLFSFSNSQKAYAGRLA 350
Cdd:pfam10459 236 VKEGDFVFVAGYPGSTSRYLTSAEVEERRDWVNPARIDRRGERQALLEREMLKDPEIRIKYASKLAGSANYWKNLIGMLE 315

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979879409  351 GLRDAYLMARKRDFEKNFKNSVLNNPNLKAKYGNLWDEIAKYQVEKTKLFHELQAYSFTGPSRSVYFRIANDLVEYAEQM 430
Cdd:pfam10459 316 GLRDLDVLAKKQAREAALRAWLRKDPARRKKYGDALDELDALQAERRDLARRYYYFEEAFSGGSELLSAARTLVRLAKER 395

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979879409  431 KLPEERRADAYKGERLKATKVRIFPQE--IETELEKAILIYQLN-YMKSVFGEKNQAFNELLKGK---SPEEVVDNLLNV 504
Cdd:pfam10459 396 EKPDAEREPGYQERALPTLKKSLERIDadYDPEVDKAVLAAMLEeYRELLGADRLPAVDKLLGKEfkgSPDAYADRLYAG 475

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979879409  505 TILSDKEKVTALLEGNPDDILKSNDPFISFVVKTRQRALEVREKYNSVSAKESAKLQLLGRAIFDVYG-TSIPPDATFTL 583
Cdd:pfam10459 476 SKLTDPANRLALLEGGKAAVEASKDPMIALAVALADARRALEKAEKELDGAIERARPLYAKARLAMYGsTPVYPDANSTL 555

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979879409  584 RIADGVVKSYEYNGTI-APPITTFYGLYDRHYsfktTNRTDWELPERWKNLPSTFD--------LSTPLNFVATNDIIGG 654
Cdd:pfam10459 556 RLTYGQVKGYSPRDGVyYPPFTTLDGVFEKED----TGEEPFDVPEKLLDAIEAKDfgryaaenGSVPVNFLSTNDITGG 631

                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 979879409  655 NSGSPVVNMNLEVVGLIFDGNIESLPGDFIYVDEKNRAVAVDVRGIVEALRHIYNADRLVDELE 718
Cdd:pfam10459 632 NSGSPVLNGKGELVGLAFDGNWESLSGDIGFDPDLQRAVAVDIRYILWALDKVYGADHLIDELT 695
 
Name Accession Description Interval E-value
Peptidase_S46 pfam10459
Peptidase S46; Dipeptidyl-peptidase 7 (DPP-7) is the best characterized member of this family. ...
 49-718 0e+00

Peptidase S46; Dipeptidyl-peptidase 7 (DPP-7) is the best characterized member of this family. It is a serine peptidase that is located on the cell surface and is predicted to have two N-terminal transmembrane domains.


Pssm-ID: 431297  Cd Length: 695  Bit Score: 640.08  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979879409   49 MWTFDYPPI--DYFKKtYNFTPTSDWFEKARLSALR-----LPGCSASFVSEDGLVMTNHHCARGALDAVNREGENLPET 121
Cdd:pfam10459   4 MWTPQQLPEqaDKLKA-LGLEIDAEWLYNLRRSSKDavvrfGGGCTGSFVSPDGLVLTNHHCAYGAIQQHSSVEHDYLKD 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979879409  122 GFYAATLEEERKIPNHYVDQLIYIGDVTDEIQKAFEEGKTDAERVANRDKKIREIQqryyeefKKSNPEDSIVASVVTFY 201
Cdd:pfam10459  83 GFLAKSRAEELPAPGLRVTVLVRITDVTDRVRAALKAGTDGEERSKAIEARLKALA-------KECEKEDGLRCEVVAFY 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979879409  202 NGGKYSIYVYKRYTDVRLVYAPETIVAYFGGDPDNFTYPRYDLDVAFFRVY-----------KDGKPLKTKYYFPFSKTG 270
Cdd:pfam10459 156 GGNEYYLYKYREYKDVRLVFAPPSSIGKFGGDTDNWMWPRHTGDFSFFRAYagkdgkpadysKDNVPYKPKHFLKISLKG 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979879409  271 VKEGDPVFVIGNPGRTNRLLTVSQLEFFRDVSYPYTLSVLDNLVRIYSDFIAKHPDKKLKYQTRLFSFSNSQKAYAGRLA 350
Cdd:pfam10459 236 VKEGDFVFVAGYPGSTSRYLTSAEVEERRDWVNPARIDRRGERQALLEREMLKDPEIRIKYASKLAGSANYWKNLIGMLE 315

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979879409  351 GLRDAYLMARKRDFEKNFKNSVLNNPNLKAKYGNLWDEIAKYQVEKTKLFHELQAYSFTGPSRSVYFRIANDLVEYAEQM 430
Cdd:pfam10459 316 GLRDLDVLAKKQAREAALRAWLRKDPARRKKYGDALDELDALQAERRDLARRYYYFEEAFSGGSELLSAARTLVRLAKER 395

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979879409  431 KLPEERRADAYKGERLKATKVRIFPQE--IETELEKAILIYQLN-YMKSVFGEKNQAFNELLKGK---SPEEVVDNLLNV 504
Cdd:pfam10459 396 EKPDAEREPGYQERALPTLKKSLERIDadYDPEVDKAVLAAMLEeYRELLGADRLPAVDKLLGKEfkgSPDAYADRLYAG 475

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979879409  505 TILSDKEKVTALLEGNPDDILKSNDPFISFVVKTRQRALEVREKYNSVSAKESAKLQLLGRAIFDVYG-TSIPPDATFTL 583
Cdd:pfam10459 476 SKLTDPANRLALLEGGKAAVEASKDPMIALAVALADARRALEKAEKELDGAIERARPLYAKARLAMYGsTPVYPDANSTL 555

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979879409  584 RIADGVVKSYEYNGTI-APPITTFYGLYDRHYsfktTNRTDWELPERWKNLPSTFD--------LSTPLNFVATNDIIGG 654
Cdd:pfam10459 556 RLTYGQVKGYSPRDGVyYPPFTTLDGVFEKED----TGEEPFDVPEKLLDAIEAKDfgryaaenGSVPVNFLSTNDITGG 631

                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 979879409  655 NSGSPVVNMNLEVVGLIFDGNIESLPGDFIYVDEKNRAVAVDVRGIVEALRHIYNADRLVDELE 718
Cdd:pfam10459 632 NSGSPVLNGKGELVGLAFDGNWESLSGDIGFDPDLQRAVAVDIRYILWALDKVYGADHLIDELT 695
Trypsin_2 pfam13365
Trypsin-like peptidase domain; This family includes trypsin-like peptidase domains.
 86-128 6.84e-03

Trypsin-like peptidase domain; This family includes trypsin-like peptidase domains.


Pssm-ID: 433149 [Multi-domain]  Cd Length: 142  Bit Score: 37.79  E-value: 6.84e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 979879409   86 CSASFVSEDGLVMTNHHCARGALDA-VNREGENLPETGFYAATL 128
Cdd:pfam13365   1 GTGFVVSSDGLVLTNAHVVDDAEEAaVELVSVVLADGREYPATV 44
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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