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Conserved domains on  [gi|2429714553|tpg|DBA05436|]
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TPA: hypothetical protein N0F65_007598, partial [Lagenidium giganteum]

Protein Classification

alpha/beta fold hydrolase( domain architecture ID 11426811)

alpha/beta hydrolase family protein catalyzes the hydrolysis of substrates with different chemical composition or physicochemical properties using a nucleophile-His-acid catalytic triad

PubMed:  1409539|12369917

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 47-128 2.03e-06

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


:

Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 44.99  E-value: 2.03e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429714553  47 LGQTAAALSHYVSDERLREIRdhgFPILLLGGNKDIIIPAREMHTLHRIMGDAEHVEcimYEDAGHGVFVKYVDEIAEDI 126
Cdd:COG0596   141 LAALLRALARTDLRERLARIT---VPTLVIWGEKDPIVPPALARRLAELLPNAELVV---LPGAGHFPPLEQPEAFAAAL 214


                  ..
gi 2429714553 127 SE 128
Cdd:COG0596   215 RD 216
 
Name Accession Description Interval E-value
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 47-128 2.03e-06

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 44.99  E-value: 2.03e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429714553  47 LGQTAAALSHYVSDERLREIRdhgFPILLLGGNKDIIIPAREMHTLHRIMGDAEHVEcimYEDAGHGVFVKYVDEIAEDI 126
Cdd:COG0596   141 LAALLRALARTDLRERLARIT---VPTLVIWGEKDPIVPPALARRLAELLPNAELVV---LPGAGHFPPLEQPEAFAAAL 214


                  ..
gi 2429714553 127 SE 128
Cdd:COG0596   215 RD 216
DLH pfam01738
Dienelactone hydrolase family;
43-125 6.55e-05

Dienelactone hydrolase family;


Pssm-ID: 396343 [Multi-domain]  Cd Length: 213  Bit Score: 40.80  E-value: 6.55e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429714553  43 LAGLLGQTAAALSHYVS--DERLREIRDHGFPILLLGGNKDIIIPAREMHTLHRIMGDAE-HVECIMYEDAGHGVFVK-- 117
Cdd:pfam01738 113 LAAKGPLVDAAVGFYGVgpEPPLIEAPDIKAPILFHFGEEDHFVPADSRELIEEALKAANvDHQIHSYPGAGHAFANDsr 192

                          90
                  ....*....|
gi 2429714553 118 --YVDEIAED 125
Cdd:pfam01738 193 psYNAAAAED 202
 
Name Accession Description Interval E-value
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 47-128 2.03e-06

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 44.99  E-value: 2.03e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429714553  47 LGQTAAALSHYVSDERLREIRdhgFPILLLGGNKDIIIPAREMHTLHRIMGDAEHVEcimYEDAGHGVFVKYVDEIAEDI 126
Cdd:COG0596   141 LAALLRALARTDLRERLARIT---VPTLVIWGEKDPIVPPALARRLAELLPNAELVV---LPGAGHFPPLEQPEAFAAAL 214


                  ..
gi 2429714553 127 SE 128
Cdd:COG0596   215 RD 216
DLH pfam01738
Dienelactone hydrolase family;
43-125 6.55e-05

Dienelactone hydrolase family;


Pssm-ID: 396343 [Multi-domain]  Cd Length: 213  Bit Score: 40.80  E-value: 6.55e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429714553  43 LAGLLGQTAAALSHYVS--DERLREIRDHGFPILLLGGNKDIIIPAREMHTLHRIMGDAE-HVECIMYEDAGHGVFVK-- 117
Cdd:pfam01738 113 LAAKGPLVDAAVGFYGVgpEPPLIEAPDIKAPILFHFGEEDHFVPADSRELIEEALKAANvDHQIHSYPGAGHAFANDsr 192

                          90
                  ....*....|
gi 2429714553 118 --YVDEIAED 125
Cdd:pfam01738 193 psYNAAAAED 202
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
39-128 2.96e-04

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 38.83  E-value: 2.96e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429714553  39 PFPSLAGLLGQTAAALSHYVSDERLREIRdhgFPILLLGGNKDIIIPAREMHTLHRIMgdAEHVECIMYEDAGHGVFV-K 117
Cdd:COG2267   132 PAYRADPLLGPSARWLRALRLAEALARID---VPVLVLHGGADRVVPPEAARRLAARL--SPDVELVLLPGARHELLNeP 206

                          90
                  ....*....|.
gi 2429714553 118 YVDEIAEDISE 128
Cdd:COG2267   207 AREEVLAAILA 217
DLH COG0412
Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];
43-113 2.10e-03

Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440181 [Multi-domain]  Cd Length: 226  Bit Score: 36.48  E-value: 2.10e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2429714553  43 LAGLLGQTAAALSHY---VSDERLREIRDHGFPILLLGGNKDIIIPAREMHTLHRIMGDAE-HVECIMYEDAGHG 113
Cdd:COG0412   126 AAARGPDLAAAVSFYgglPADDLLDLAARIKAPVLLLYGEKDPLVPPEQVAALEAALAAAGvDVELHVYPGAGHG 200
YvaK COG1647
Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];
21-128 5.97e-03

Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 441253 [Multi-domain]  Cd Length: 246  Bit Score: 35.30  E-value: 5.97e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429714553  21 QSMRDVMRDCLVHRIGYRPFPSLAGllgQTAAALSHYVSdERLREIRdhgFPILLLGGNKDIIIPAREMHTLHRIMGdAE 100
Cdd:COG1647   139 RGIGSDIEDPEVAEYAYDRTPLRAL---AELQRLIREVR-RDLPKIT---APTLIIQSRKDEVVPPESARYIYERLG-SP 210

                          90       100
                  ....*....|....*....|....*....
gi 2429714553 101 HVECIMYEDAGHGVFVKY-VDEIAEDISE 128
Cdd:COG1647   211 DKELVWLEDSGHVITLDKdREEVAEEILD 239
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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