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Conserved domains on  [gi|70885466|gb|EAN98283|]
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retrotransposon hot spot (RHS) protein, putative [Trypanosoma cruzi]

Protein Classification

RHS family protein( domain architecture ID 140249)

RHS (retrotransposon hot spot) family protein similar to Trypanosoma brucei RHS proteins

Gene Ontology:  GO:0003729

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
RHSP super family cl19421
Retrotransposon hot spot protein, P-loop domain; Members of this entry are retrotransposon hot ...
255-966 0e+00

Retrotransposon hot spot protein, P-loop domain; Members of this entry are retrotransposon hot spot proteins (RHSPs). They are associated with polymorphic subtelomeric regions in Trypanosoma. These proteins contain a P-loop (ATP/GTP-binding) motif, represented in this entry, at the C-terminal of the conserved box 1. This domain also includes the retrotransposon insertion site.


The actual alignment was detected with superfamily member TIGR01631:

Pssm-ID: 473170  Cd Length: 760  Bit Score: 611.45  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466   255 FTISTTIEEALFKGGVRVKEKKLNDFLTMELGGRGVVATNRSVLLKEFFKDPTKYIRDKGVLKEIQITDAYarmEGVVRD 334
Cdd:TIGR01631  17 WTMDSRVEDVLLEDYAGLRNMKLNDFLWKNFGGTYNVDETENVSMKVFVQSPEDYILDAGALNRIQATDEF---ERVKNN 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466   335 EMDMEEDIKKLYKNGVRTLLKWSE-AAAEVKAGVHDITNEFLDAALVELRDP-----TTTGASEkLEGYYESVYNARWSH 408
Cdd:TIGR01631  94 FVVFDEKVRYLDENEINTLSQWEEkAKGEIREFVGPVARGRLDPALEAAKEAekraaQAADGVE-LEGVYDSIYNAKWSY 172
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466   409 VVEIPDGDGTGLEVREGKPEQSWTYKKFGDTLEKDDGVEQSdaPRP---RLMVLTSDKGWPYSWNMT------QNSSEDF 479
Cdd:TIGR01631 173 VESGHGTEPLGMKVVDGRPPHMWTEEEVDVSPEPEDLAEQL--PRHgglEIAVLTSEKGWPYTSFAKgvnsiqEEAEKDV 250
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466   480 FVNCEVERVWRIVRNDLTEWFSNSDLTLsssPVRRLLIGTPGIGKSVAASSYLLYQLLQYDIYKLQVVVHCFGGRdAYVF 559
Cdd:TIGR01631 251 YIRREVLRVWYIVKNGLTLWLSSHAKFE---PERRVLIGTPGIGKSFGVGSFLLYQLLHYDAEKLQVVAYFVAGR-AYLF 326
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466   560 DKTTK----IVTRYSDEDQCITALRSLRKRGMKGYIIYDVAKKGTPPLrHFLPTTGWGMIVVSSPKASNYDEWEKQLQAS 635
Cdd:TIGR01631 327 DKTSGggvgRVSFYEKDKAAADVVEALSDEKVKGYIIYDFAKDDDEPP-PADPPSGWGVILLSSPNESNFKEWSKQRGCT 405
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466   636 RIIMNCPDEMDVKAMCAWMKR---------DETAEKKTEYWRMVKERIEKVGPIPRHIFYVDEYRKRTQDVMRALKWINL 706
Cdd:TIGR01631 406 RIVMNCDEESDMKAFVAWRGLsqapeykitEATPEELEEEWEVIKSRIDEVGPLPRYVFGEKKYTRRVQRCNEAIDEISS 485
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466   707 GEQGKYF-TQGGEKKWYSEDSSQKLLKVVRVR-EGSAFEDFTNAPICDYLGVLTLSRLAKALSPHDILFLVLGMKNVLQP 784
Cdd:TIGR01631 486 DDISHYNgVVGNRGSWRCDKVSHKLVKIVRVRgEDCSGEEYRCRPVSAHIGNKILFKLAKIMQQKDANSLVLESTRELAA 565
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466   785 AALEKYALSVFLSVEFVTSIVKDLKELPPPSPSETRSSVLTlnpHGYPTEAAAITELKFIDGPET----LKYRVLYIPTF 860
Cdd:TIGR01631 566 ENFERCAVFALLFGNVVRGIARRLRYLPRPGEQRQSHRVLL---AVYEQELSTRHHVLPPDEHFSeiidIEYGVLYKPEV 642
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466   861 PTFPLVDGFFFVDSP----------RKTLVGLQMTTASAHNTTASTVRQFKDDMATYFDGWDELSRDMSWDIIYIQHADS 930
Cdd:TIGR01631 643 GNFPVVDAFFFVESPaiaedkqrreKKTIVGLQYTVAGRHHTTTGTVRKFTEYLAAYFNGWDELSRQLVWEIIYVQHVDS 722
                         730       740       750
                  ....*....|....*....|....*....|....*.
gi 70885466   931 KPMEKWQRCDYVNSRNKTDAEkEIVAFWDGKVHQYQ 966
Cdd:TIGR01631 723 TPITDWQRCDVVDSAEGADNN-EIEVFWKNKVRQYQ 757
 
Name Accession Description Interval E-value
Trypano_RHS TIGR01631
trypanosome RHS (retrotransposon hot spot) family; This model describes full-length and ...
255-966 0e+00

trypanosome RHS (retrotransposon hot spot) family; This model describes full-length and part-length members of the RHS (retrotransposon hot spot) family in Trypanosoma brucei and Trypanosoma cruzi. Members of this family are frequently interrupted by non-LTR retrotransposons inserted at exactly the same relative position.


Pssm-ID: 273724  Cd Length: 760  Bit Score: 611.45  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466   255 FTISTTIEEALFKGGVRVKEKKLNDFLTMELGGRGVVATNRSVLLKEFFKDPTKYIRDKGVLKEIQITDAYarmEGVVRD 334
Cdd:TIGR01631  17 WTMDSRVEDVLLEDYAGLRNMKLNDFLWKNFGGTYNVDETENVSMKVFVQSPEDYILDAGALNRIQATDEF---ERVKNN 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466   335 EMDMEEDIKKLYKNGVRTLLKWSE-AAAEVKAGVHDITNEFLDAALVELRDP-----TTTGASEkLEGYYESVYNARWSH 408
Cdd:TIGR01631  94 FVVFDEKVRYLDENEINTLSQWEEkAKGEIREFVGPVARGRLDPALEAAKEAekraaQAADGVE-LEGVYDSIYNAKWSY 172
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466   409 VVEIPDGDGTGLEVREGKPEQSWTYKKFGDTLEKDDGVEQSdaPRP---RLMVLTSDKGWPYSWNMT------QNSSEDF 479
Cdd:TIGR01631 173 VESGHGTEPLGMKVVDGRPPHMWTEEEVDVSPEPEDLAEQL--PRHgglEIAVLTSEKGWPYTSFAKgvnsiqEEAEKDV 250
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466   480 FVNCEVERVWRIVRNDLTEWFSNSDLTLsssPVRRLLIGTPGIGKSVAASSYLLYQLLQYDIYKLQVVVHCFGGRdAYVF 559
Cdd:TIGR01631 251 YIRREVLRVWYIVKNGLTLWLSSHAKFE---PERRVLIGTPGIGKSFGVGSFLLYQLLHYDAEKLQVVAYFVAGR-AYLF 326
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466   560 DKTTK----IVTRYSDEDQCITALRSLRKRGMKGYIIYDVAKKGTPPLrHFLPTTGWGMIVVSSPKASNYDEWEKQLQAS 635
Cdd:TIGR01631 327 DKTSGggvgRVSFYEKDKAAADVVEALSDEKVKGYIIYDFAKDDDEPP-PADPPSGWGVILLSSPNESNFKEWSKQRGCT 405
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466   636 RIIMNCPDEMDVKAMCAWMKR---------DETAEKKTEYWRMVKERIEKVGPIPRHIFYVDEYRKRTQDVMRALKWINL 706
Cdd:TIGR01631 406 RIVMNCDEESDMKAFVAWRGLsqapeykitEATPEELEEEWEVIKSRIDEVGPLPRYVFGEKKYTRRVQRCNEAIDEISS 485
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466   707 GEQGKYF-TQGGEKKWYSEDSSQKLLKVVRVR-EGSAFEDFTNAPICDYLGVLTLSRLAKALSPHDILFLVLGMKNVLQP 784
Cdd:TIGR01631 486 DDISHYNgVVGNRGSWRCDKVSHKLVKIVRVRgEDCSGEEYRCRPVSAHIGNKILFKLAKIMQQKDANSLVLESTRELAA 565
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466   785 AALEKYALSVFLSVEFVTSIVKDLKELPPPSPSETRSSVLTlnpHGYPTEAAAITELKFIDGPET----LKYRVLYIPTF 860
Cdd:TIGR01631 566 ENFERCAVFALLFGNVVRGIARRLRYLPRPGEQRQSHRVLL---AVYEQELSTRHHVLPPDEHFSeiidIEYGVLYKPEV 642
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466   861 PTFPLVDGFFFVDSP----------RKTLVGLQMTTASAHNTTASTVRQFKDDMATYFDGWDELSRDMSWDIIYIQHADS 930
Cdd:TIGR01631 643 GNFPVVDAFFFVESPaiaedkqrreKKTIVGLQYTVAGRHHTTTGTVRKFTEYLAAYFNGWDELSRQLVWEIIYVQHVDS 722
                         730       740       750
                  ....*....|....*....|....*....|....*.
gi 70885466   931 KPMEKWQRCDYVNSRNKTDAEkEIVAFWDGKVHQYQ 966
Cdd:TIGR01631 723 TPITDWQRCDVVDSAEGADNN-EIEVFWKNKVRQYQ 757
RHSP pfam07999
Retrotransposon hot spot protein, P-loop domain; Members of this entry are retrotransposon hot ...
515-812 3.25e-75

Retrotransposon hot spot protein, P-loop domain; Members of this entry are retrotransposon hot spot proteins (RHSPs). They are associated with polymorphic subtelomeric regions in Trypanosoma. These proteins contain a P-loop (ATP/GTP-binding) motif, represented in this entry, at the C-terminal of the conserved box 1. This domain also includes the retrotransposon insertion site.


Pssm-ID: 462336  Cd Length: 312  Bit Score: 249.84  E-value: 3.25e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466   515 LLIGTPGIGKSVAASSYLLYQLLQYDIYKLQVVVHCFGGRdAYVFDKTTK----IVTRYSDEDQCITALRSLRKRGMKGY 590
Cdd:pfam07999   1 VLTGTPGIGKSMAVGSFLLYQLLHYDAELLPIIAYSVCGK-AYVFNKTTEdhpgTVTFYMDMSMMIKAVKELSREGMKGY 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466   591 IIYDVAKKGTPPLRhFLPTTGWGMIVVSSPKASNYDEWEKQLQASRIIMNCPDEMDVKAMCAWMKRD--------ETAEK 662
Cdd:pfam07999  80 IIYDVGKRLDTPSP-FLPPGGWGMIVLASPDKTSYIEWANEKRAVRIIINCPDESDLKAMCVWKKRNqpeesppqQAEIN 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466   663 KTEYWRMVKERIEKVGPIPRHIFYVDEYRKRTQDVMRALKWINLGEQGKYFTQ-GGEKKWYSEDSSQKLLKVVRVREGSA 741
Cdd:pfam07999 159 VENEWQEIKGRIDKVGPLLRYIFYEGSYKYWIAKIHEAVDETSSWGIQSYMSVfGTSKLWEGNKVLEYLARIVRVRGENG 238
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 70885466   742 FEDFtNAPICDYLGVLTLSRLAKALSPHDILFLVL--GMKNVLQPAA--LEKYALSVFLSVEFVTSIVKDLKELP 812
Cdd:pfam07999 239 ESCF-NAPISAYLAQKTLCKLRQWMTQAEFNLFVSrkGIRDCLMHAAdnFEKCGIFAFLNVNFMAAIRRKLRELP 312
PTZ00209 PTZ00209
retrotransposon hot spot protein; Provisional
381-973 2.64e-74

retrotransposon hot spot protein; Provisional


Pssm-ID: 140236  Cd Length: 693  Bit Score: 258.80  E-value: 2.64e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466  381 ELRDPTTTGASE-KLEGYYESVYNARWSHVVEIPDGDGTGLEVREGKPEQSWTYKKFGDTLEKDDgVEQSDAPRP---RL 456
Cdd:PTZ00209  33 QMQNPSVTGKRKsREEELYESLYYAKWSYVMSGYNQEPLGMKVFFGRPQHIWTEEEVDITPEHCE-VDAELEERPtglEI 111
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466  457 MVLTSDKGWPYS------WNMTQNS---SEDFFVNCEVERVWRIVRNDLTEWFSNSDltlSSSPVRRLLIGTPGIGKSVA 527
Cdd:PTZ00209 112 FVLTSKMGWPSDrfqcslISLYDESgimDNNVYIRREMMRVWYIIQRKLNAWWVQKT---ESTPPTHIVIGISGIGKSCG 188
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466  528 ASSYLLYQLLQYDIYKLQVVVHcFGGRDAY-VFDKTTK-----IVTRYSDEDQCITALRsLRKRGmkgYIIYDV-AKKGT 600
Cdd:PTZ00209 189 VGSFLLHSLLHFHEGMLDVVVY-FTDVKAYlIYNKKGNeegrvVLYKRKDVTNVIEEMR-LKKRG---HIIFDInSPKET 263
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466  601 PPLRhfLPTTGWGMIVVSSPKASNYDEWEKQLQASRIIMNCPDEMDVKAMCAWMKR---------DETAEKKT-----EY 666
Cdd:PTZ00209 264 LPYE--IPRNVWGVTVLAPPDGVRYKYWMKNLEQTRIILNCDDVRDIKAFVAWKKLslfpnyttlDENARAKVkeeleDE 341
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466  667 WRMVKERIEKVGPIPRHIFyVDEYRKRTQDVMRALKWINLGEQ-------GKYFTqggekkWYSEDSSQKLLKVVRvrEG 739
Cdd:PTZ00209 342 WRLVERRVDVVGPLPRYVF-SNGATCREAAVIDYLSSLSCNRRdgydmmmGKYFE------WKGNHFTESLIKIVR--ER 412
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466  740 SAFEDFTN---APICDYLGVLTLSRL----AKALSPHDILfLVLGMknvLQPAALEKYALSVFLSVEFVTSIVKDLKELP 812
Cdd:PTZ00209 413 SRYGNLESyhcRPLSVAIGNMILCTLfatvAESMSSHEFM-MEYGK---VGAYSLKTRALVSLLFPRVFCVVTKHLNYLR 488
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466  813 PPSPSETRSSVLT-LNPHGYpteaaAITELKFIdgPET-------LKYRVLYIPTFPTFPLVDGFFFV-DSPR------- 876
Cdd:PTZ00209 489 RLGETEDKRSILKdMTPQQF-----QIFEQKFL--PKTgqnaignCKYKVLYRSLEESKLFVDGFFFVeDCSRrvadmrd 561
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466  877 ---------KTLVGLQMTTASAHNTTASTVRQFKDDMATYFDGWDELSRDMSWDIIYIQHADSKPMEKWQRCdyVNSrNK 947
Cdd:PTZ00209 562 gfpqlgvasKTIVLIQITDNYRKEASVSELQEFMTNIARYFSDWDTFSRNMAWEMIYVNAIYGGVIKTRQRC--VNN-NT 638
                        650       660
                 ....*....|....*....|....*....
gi 70885466  948 TDAEK---EIVAFWDGkVHQYQFVLTTEL 973
Cdd:PTZ00209 639 ADAEQqteETQVFWDG-IDQYQITFDNKI 666
 
Name Accession Description Interval E-value
Trypano_RHS TIGR01631
trypanosome RHS (retrotransposon hot spot) family; This model describes full-length and ...
255-966 0e+00

trypanosome RHS (retrotransposon hot spot) family; This model describes full-length and part-length members of the RHS (retrotransposon hot spot) family in Trypanosoma brucei and Trypanosoma cruzi. Members of this family are frequently interrupted by non-LTR retrotransposons inserted at exactly the same relative position.


Pssm-ID: 273724  Cd Length: 760  Bit Score: 611.45  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466   255 FTISTTIEEALFKGGVRVKEKKLNDFLTMELGGRGVVATNRSVLLKEFFKDPTKYIRDKGVLKEIQITDAYarmEGVVRD 334
Cdd:TIGR01631  17 WTMDSRVEDVLLEDYAGLRNMKLNDFLWKNFGGTYNVDETENVSMKVFVQSPEDYILDAGALNRIQATDEF---ERVKNN 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466   335 EMDMEEDIKKLYKNGVRTLLKWSE-AAAEVKAGVHDITNEFLDAALVELRDP-----TTTGASEkLEGYYESVYNARWSH 408
Cdd:TIGR01631  94 FVVFDEKVRYLDENEINTLSQWEEkAKGEIREFVGPVARGRLDPALEAAKEAekraaQAADGVE-LEGVYDSIYNAKWSY 172
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466   409 VVEIPDGDGTGLEVREGKPEQSWTYKKFGDTLEKDDGVEQSdaPRP---RLMVLTSDKGWPYSWNMT------QNSSEDF 479
Cdd:TIGR01631 173 VESGHGTEPLGMKVVDGRPPHMWTEEEVDVSPEPEDLAEQL--PRHgglEIAVLTSEKGWPYTSFAKgvnsiqEEAEKDV 250
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466   480 FVNCEVERVWRIVRNDLTEWFSNSDLTLsssPVRRLLIGTPGIGKSVAASSYLLYQLLQYDIYKLQVVVHCFGGRdAYVF 559
Cdd:TIGR01631 251 YIRREVLRVWYIVKNGLTLWLSSHAKFE---PERRVLIGTPGIGKSFGVGSFLLYQLLHYDAEKLQVVAYFVAGR-AYLF 326
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466   560 DKTTK----IVTRYSDEDQCITALRSLRKRGMKGYIIYDVAKKGTPPLrHFLPTTGWGMIVVSSPKASNYDEWEKQLQAS 635
Cdd:TIGR01631 327 DKTSGggvgRVSFYEKDKAAADVVEALSDEKVKGYIIYDFAKDDDEPP-PADPPSGWGVILLSSPNESNFKEWSKQRGCT 405
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466   636 RIIMNCPDEMDVKAMCAWMKR---------DETAEKKTEYWRMVKERIEKVGPIPRHIFYVDEYRKRTQDVMRALKWINL 706
Cdd:TIGR01631 406 RIVMNCDEESDMKAFVAWRGLsqapeykitEATPEELEEEWEVIKSRIDEVGPLPRYVFGEKKYTRRVQRCNEAIDEISS 485
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466   707 GEQGKYF-TQGGEKKWYSEDSSQKLLKVVRVR-EGSAFEDFTNAPICDYLGVLTLSRLAKALSPHDILFLVLGMKNVLQP 784
Cdd:TIGR01631 486 DDISHYNgVVGNRGSWRCDKVSHKLVKIVRVRgEDCSGEEYRCRPVSAHIGNKILFKLAKIMQQKDANSLVLESTRELAA 565
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466   785 AALEKYALSVFLSVEFVTSIVKDLKELPPPSPSETRSSVLTlnpHGYPTEAAAITELKFIDGPET----LKYRVLYIPTF 860
Cdd:TIGR01631 566 ENFERCAVFALLFGNVVRGIARRLRYLPRPGEQRQSHRVLL---AVYEQELSTRHHVLPPDEHFSeiidIEYGVLYKPEV 642
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466   861 PTFPLVDGFFFVDSP----------RKTLVGLQMTTASAHNTTASTVRQFKDDMATYFDGWDELSRDMSWDIIYIQHADS 930
Cdd:TIGR01631 643 GNFPVVDAFFFVESPaiaedkqrreKKTIVGLQYTVAGRHHTTTGTVRKFTEYLAAYFNGWDELSRQLVWEIIYVQHVDS 722
                         730       740       750
                  ....*....|....*....|....*....|....*.
gi 70885466   931 KPMEKWQRCDYVNSRNKTDAEkEIVAFWDGKVHQYQ 966
Cdd:TIGR01631 723 TPITDWQRCDVVDSAEGADNN-EIEVFWKNKVRQYQ 757
RHSP pfam07999
Retrotransposon hot spot protein, P-loop domain; Members of this entry are retrotransposon hot ...
515-812 3.25e-75

Retrotransposon hot spot protein, P-loop domain; Members of this entry are retrotransposon hot spot proteins (RHSPs). They are associated with polymorphic subtelomeric regions in Trypanosoma. These proteins contain a P-loop (ATP/GTP-binding) motif, represented in this entry, at the C-terminal of the conserved box 1. This domain also includes the retrotransposon insertion site.


Pssm-ID: 462336  Cd Length: 312  Bit Score: 249.84  E-value: 3.25e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466   515 LLIGTPGIGKSVAASSYLLYQLLQYDIYKLQVVVHCFGGRdAYVFDKTTK----IVTRYSDEDQCITALRSLRKRGMKGY 590
Cdd:pfam07999   1 VLTGTPGIGKSMAVGSFLLYQLLHYDAELLPIIAYSVCGK-AYVFNKTTEdhpgTVTFYMDMSMMIKAVKELSREGMKGY 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466   591 IIYDVAKKGTPPLRhFLPTTGWGMIVVSSPKASNYDEWEKQLQASRIIMNCPDEMDVKAMCAWMKRD--------ETAEK 662
Cdd:pfam07999  80 IIYDVGKRLDTPSP-FLPPGGWGMIVLASPDKTSYIEWANEKRAVRIIINCPDESDLKAMCVWKKRNqpeesppqQAEIN 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466   663 KTEYWRMVKERIEKVGPIPRHIFYVDEYRKRTQDVMRALKWINLGEQGKYFTQ-GGEKKWYSEDSSQKLLKVVRVREGSA 741
Cdd:pfam07999 159 VENEWQEIKGRIDKVGPLLRYIFYEGSYKYWIAKIHEAVDETSSWGIQSYMSVfGTSKLWEGNKVLEYLARIVRVRGENG 238
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 70885466   742 FEDFtNAPICDYLGVLTLSRLAKALSPHDILFLVL--GMKNVLQPAA--LEKYALSVFLSVEFVTSIVKDLKELP 812
Cdd:pfam07999 239 ESCF-NAPISAYLAQKTLCKLRQWMTQAEFNLFVSrkGIRDCLMHAAdnFEKCGIFAFLNVNFMAAIRRKLRELP 312
PTZ00209 PTZ00209
retrotransposon hot spot protein; Provisional
381-973 2.64e-74

retrotransposon hot spot protein; Provisional


Pssm-ID: 140236  Cd Length: 693  Bit Score: 258.80  E-value: 2.64e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466  381 ELRDPTTTGASE-KLEGYYESVYNARWSHVVEIPDGDGTGLEVREGKPEQSWTYKKFGDTLEKDDgVEQSDAPRP---RL 456
Cdd:PTZ00209  33 QMQNPSVTGKRKsREEELYESLYYAKWSYVMSGYNQEPLGMKVFFGRPQHIWTEEEVDITPEHCE-VDAELEERPtglEI 111
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466  457 MVLTSDKGWPYS------WNMTQNS---SEDFFVNCEVERVWRIVRNDLTEWFSNSDltlSSSPVRRLLIGTPGIGKSVA 527
Cdd:PTZ00209 112 FVLTSKMGWPSDrfqcslISLYDESgimDNNVYIRREMMRVWYIIQRKLNAWWVQKT---ESTPPTHIVIGISGIGKSCG 188
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466  528 ASSYLLYQLLQYDIYKLQVVVHcFGGRDAY-VFDKTTK-----IVTRYSDEDQCITALRsLRKRGmkgYIIYDV-AKKGT 600
Cdd:PTZ00209 189 VGSFLLHSLLHFHEGMLDVVVY-FTDVKAYlIYNKKGNeegrvVLYKRKDVTNVIEEMR-LKKRG---HIIFDInSPKET 263
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466  601 PPLRhfLPTTGWGMIVVSSPKASNYDEWEKQLQASRIIMNCPDEMDVKAMCAWMKR---------DETAEKKT-----EY 666
Cdd:PTZ00209 264 LPYE--IPRNVWGVTVLAPPDGVRYKYWMKNLEQTRIILNCDDVRDIKAFVAWKKLslfpnyttlDENARAKVkeeleDE 341
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466  667 WRMVKERIEKVGPIPRHIFyVDEYRKRTQDVMRALKWINLGEQ-------GKYFTqggekkWYSEDSSQKLLKVVRvrEG 739
Cdd:PTZ00209 342 WRLVERRVDVVGPLPRYVF-SNGATCREAAVIDYLSSLSCNRRdgydmmmGKYFE------WKGNHFTESLIKIVR--ER 412
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466  740 SAFEDFTN---APICDYLGVLTLSRL----AKALSPHDILfLVLGMknvLQPAALEKYALSVFLSVEFVTSIVKDLKELP 812
Cdd:PTZ00209 413 SRYGNLESyhcRPLSVAIGNMILCTLfatvAESMSSHEFM-MEYGK---VGAYSLKTRALVSLLFPRVFCVVTKHLNYLR 488
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466  813 PPSPSETRSSVLT-LNPHGYpteaaAITELKFIdgPET-------LKYRVLYIPTFPTFPLVDGFFFV-DSPR------- 876
Cdd:PTZ00209 489 RLGETEDKRSILKdMTPQQF-----QIFEQKFL--PKTgqnaignCKYKVLYRSLEESKLFVDGFFFVeDCSRrvadmrd 561
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466  877 ---------KTLVGLQMTTASAHNTTASTVRQFKDDMATYFDGWDELSRDMSWDIIYIQHADSKPMEKWQRCdyVNSrNK 947
Cdd:PTZ00209 562 gfpqlgvasKTIVLIQITDNYRKEASVSELQEFMTNIARYFSDWDTFSRNMAWEMIYVNAIYGGVIKTRQRC--VNN-NT 638
                        650       660
                 ....*....|....*....|....*....
gi 70885466  948 TDAEK---EIVAFWDGkVHQYQFVLTTEL 973
Cdd:PTZ00209 639 ADAEQqteETQVFWDG-IDQYQITFDNKI 666
RHS_N pfam20445
Retrotransposon hot spot proteins N-terminal; Members of this entry are retrotransposon hot ...
398-501 4.40e-32

Retrotransposon hot spot proteins N-terminal; Members of this entry are retrotransposon hot spot (RHS) proteins. They are associated with polymorphic subtelomeric regions in Trypanosoma. These proteins contain a conserved box 1 with a P-loop motif and a retrotransposon insertion site at the C-terminal (pfam07999). This domain represents the N-terminal region of the conserved box 1 from RHSPs.


Pssm-ID: 466594 [Multi-domain]  Cd Length: 127  Bit Score: 121.28  E-value: 4.40e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70885466   398 YESVYNARWSHVVEIPDGDGTGLEVREGKPEQSWTYKKFGDTLEKDDGVEQsdAPRP---RLMVLTSDKGWPYSWNMTQN 474
Cdd:pfam20445   1 YDSIYNARWHYVMSGPNGEPLGMKVHDGEPPQSWTYEEVGVSHTPDDGVEP--LPRHgnlEIAVLTSQRGWPHPFFLSDI 78
                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 70885466   475 SSE------------DFFVNCEVERVWRIVRNDLTEWFS 501
Cdd:pfam20445  79 VCRdastkkdhvfndDVYIRREVDRVWQIVKGRLTEWLS 117
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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