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Conserved domains on  [gi|119572609|gb|EAW52224|]
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hypothetical protein MGC3121, isoform CRA_a [Homo sapiens]

Protein Classification

PHA03247 and Tantalus domain-containing protein( domain architecture ID 10634106)

PHA03247 and Tantalus domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Tantalus pfam15386
Drosophila Tantalus-like; An alpha+beta fold domain found in metazoan proteins such as ...
 304-361 4.19e-21

Drosophila Tantalus-like; An alpha+beta fold domain found in metazoan proteins such as Drosophila Tantalus. Drosophila Tantalus binds the chromatin protein Additional sex combs (Asx) and also binds DNA in vitro.


:

Pssm-ID: 464693  Cd Length: 57  Bit Score: 85.93  E-value: 4.19e-21
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 119572609  304 LTPMGLPRPIRLNKKEFSLEEIYTNKNYQSPtTRRTFETIFEEPRERNGTLIFTSSRK 361
Cdd:pfam15386   1 RTPMGLPRPIRVKKKEFSIEEIYTNKNYKKP-TNKNLETIFEEPSDENGAIVYVSSRK 57
BimA_second super family cl49131
trimeric autotransporter actin-nucleating factor BimA; This HMM describes BimA (Burkholderia ...
 38-93 4.39e-03

trimeric autotransporter actin-nucleating factor BimA; This HMM describes BimA (Burkholderia intracellular motility A), WP_004266405.1-like proteins in Burkholderia mallei or B. pseudomallei. The term BimA has also been used for WP_011205626.1-like homologs that have a very different N-terminal half.


The actual alignment was detected with superfamily member NF040983:

Pssm-ID: 468913 [Multi-domain]  Cd Length: 382  Bit Score: 39.12  E-value: 4.39e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 119572609  38 PTPPPGDLEPPFQPSALPADPLESPPTAPDPALELPSTPPPSSLLRPRLSPWGLAP 93
Cdd:NF040983  96 PPPPPPPPPTPPPPPPPPPPPPPPSPPPPPPPSPPPSPPPPTTTPPTRTTPSTTTP 151
 
Name Accession Description Interval E-value
Tantalus pfam15386
Drosophila Tantalus-like; An alpha+beta fold domain found in metazoan proteins such as ...
 304-361 4.19e-21

Drosophila Tantalus-like; An alpha+beta fold domain found in metazoan proteins such as Drosophila Tantalus. Drosophila Tantalus binds the chromatin protein Additional sex combs (Asx) and also binds DNA in vitro.


Pssm-ID: 464693  Cd Length: 57  Bit Score: 85.93  E-value: 4.19e-21
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 119572609  304 LTPMGLPRPIRLNKKEFSLEEIYTNKNYQSPtTRRTFETIFEEPRERNGTLIFTSSRK 361
Cdd:pfam15386   1 RTPMGLPRPIRVKKKEFSIEEIYTNKNYKKP-TNKNLETIFEEPSDENGAIVYVSSRK 57
BimA_second NF040983
trimeric autotransporter actin-nucleating factor BimA; This HMM describes BimA (Burkholderia ...
 38-93 4.39e-03

trimeric autotransporter actin-nucleating factor BimA; This HMM describes BimA (Burkholderia intracellular motility A), WP_004266405.1-like proteins in Burkholderia mallei or B. pseudomallei. The term BimA has also been used for WP_011205626.1-like homologs that have a very different N-terminal half.


Pssm-ID: 468913 [Multi-domain]  Cd Length: 382  Bit Score: 39.12  E-value: 4.39e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 119572609  38 PTPPPGDLEPPFQPSALPADPLESPPTAPDPALELPSTPPPSSLLRPRLSPWGLAP 93
Cdd:NF040983  96 PPPPPPPPPTPPPPPPPPPPPPPPSPPPPPPPSPPPSPPPPTTTPPTRTTPSTTTP 151
 
Name Accession Description Interval E-value
Tantalus pfam15386
Drosophila Tantalus-like; An alpha+beta fold domain found in metazoan proteins such as ...
 304-361 4.19e-21

Drosophila Tantalus-like; An alpha+beta fold domain found in metazoan proteins such as Drosophila Tantalus. Drosophila Tantalus binds the chromatin protein Additional sex combs (Asx) and also binds DNA in vitro.


Pssm-ID: 464693  Cd Length: 57  Bit Score: 85.93  E-value: 4.19e-21
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 119572609  304 LTPMGLPRPIRLNKKEFSLEEIYTNKNYQSPtTRRTFETIFEEPRERNGTLIFTSSRK 361
Cdd:pfam15386   1 RTPMGLPRPIRVKKKEFSIEEIYTNKNYKKP-TNKNLETIFEEPSDENGAIVYVSSRK 57
BimA_second NF040983
trimeric autotransporter actin-nucleating factor BimA; This HMM describes BimA (Burkholderia ...
 38-93 4.39e-03

trimeric autotransporter actin-nucleating factor BimA; This HMM describes BimA (Burkholderia intracellular motility A), WP_004266405.1-like proteins in Burkholderia mallei or B. pseudomallei. The term BimA has also been used for WP_011205626.1-like homologs that have a very different N-terminal half.


Pssm-ID: 468913 [Multi-domain]  Cd Length: 382  Bit Score: 39.12  E-value: 4.39e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 119572609  38 PTPPPGDLEPPFQPSALPADPLESPPTAPDPALELPSTPPPSSLLRPRLSPWGLAP 93
Cdd:NF040983  96 PPPPPPPPPTPPPPPPPPPPPPPPSPPPPPPPSPPPSPPPPTTTPPTRTTPSTTTP 151
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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