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Conserved domains on  [gi|119579212|gb|EAW58808|]
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very low density lipoprotein receptor, isoform CRA_c [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Ldl_recept_b pfam00058
Low-density lipoprotein receptor repeat class B; This domain is also known as the YWTD motif ...
 142-182 1.77e-14

Low-density lipoprotein receptor repeat class B; This domain is also known as the YWTD motif after the most conserved region of the repeat. The YWTD repeat is found in multiple tandem repeats and has been predicted to form a beta-propeller structure.


:

Pssm-ID: 459654  Cd Length: 42  Bit Score: 67.18  E-value: 1.77e-14
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 119579212  142 GFVYWSDWGEPAKIEKAGMNGFDRRPLVTADIQWPNGITLD 182
Cdd:pfam00058   1 GRLYWTDSSLRASISSADLNGSDRKTLFTDDLQHPNAIAVD 41
LY smart00135
Low-density lipoprotein-receptor YWTD domain; Type "B" repeats in low-density lipoprotein (LDL) ...
 79-121 1.55e-10

Low-density lipoprotein-receptor YWTD domain; Type "B" repeats in low-density lipoprotein (LDL) receptor that plays a central role in mammalian cholesterol metabolism. Also present in a variety of molecules similar to gp300/megalin.


:

Pssm-ID: 214531 [Multi-domain]  Cd Length: 43  Bit Score: 56.07  E-value: 1.55e-10
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 119579212    79 HVKMIDNVYNPAAIAVDWVYKTIYWTDAASKTISVATLDGTKR 121
Cdd:smart00135   1 RTLLSSGLGHPNGLAVDWIEGRLYWTDWGLDVIEVANLDGTNR 43
FXa_inhibition pfam14670
Coagulation Factor Xa inhibitory site; This short domain on coagulation enzyme factor Xa is ...
 280-323 2.27e-09

Coagulation Factor Xa inhibitory site; This short domain on coagulation enzyme factor Xa is found to be the target for a potent inhibitor of coagulation, TAK-442.


:

Pssm-ID: 464251 [Multi-domain]  Cd Length: 36  Bit Score: 52.63  E-value: 2.27e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 119579212  280 CEEDmeNGGCEYLCLPAPQindhspKYTCSCPSGYNVEENGRDC 323
Cdd:pfam14670   1 CSVN--NGGCSHLCLNTPG------GYTCSCPEGYELQDDGRTC 36
LY smart00135
Low-density lipoprotein-receptor YWTD domain; Type "B" repeats in low-density lipoprotein (LDL) ...
 166-208 1.96e-08

Low-density lipoprotein-receptor YWTD domain; Type "B" repeats in low-density lipoprotein (LDL) receptor that plays a central role in mammalian cholesterol metabolism. Also present in a variety of molecules similar to gp300/megalin.


:

Pssm-ID: 214531 [Multi-domain]  Cd Length: 43  Bit Score: 49.91  E-value: 1.96e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 119579212   166 RPLVTADIQWPNGITLDLIKSRLYWLDSKLHMLSSVDLNGQDR 208
Cdd:smart00135   1 RTLLSSGLGHPNGLAVDWIEGRLYWTDWGLDVIEVANLDGTNR 43
Ldl_recept_b pfam00058
Low-density lipoprotein receptor repeat class B; This domain is also known as the YWTD motif ...
 55-96 7.80e-08

Low-density lipoprotein receptor repeat class B; This domain is also known as the YWTD motif after the most conserved region of the repeat. The YWTD repeat is found in multiple tandem repeats and has been predicted to form a beta-propeller structure.


:

Pssm-ID: 459654  Cd Length: 42  Bit Score: 48.31  E-value: 7.80e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 119579212   55 QKLFWADLSQKA-IFSASIDDKVgRHVKMIDNVYNPAAIAVDW 96
Cdd:pfam00058   1 GRLYWTDSSLRAsISSADLNGSD-RKTLFTDDLQHPNAIAVDP 42
Ldl_recept_b super family cl44468
Low-density lipoprotein receptor repeat class B; This domain is also known as the YWTD motif ...
 229-269 3.93e-07

Low-density lipoprotein receptor repeat class B; This domain is also known as the YWTD motif after the most conserved region of the repeat. The YWTD repeat is found in multiple tandem repeats and has been predicted to form a beta-propeller structure.


The actual alignment was detected with superfamily member pfam00058:

Pssm-ID: 459654  Cd Length: 42  Bit Score: 46.38  E-value: 3.93e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 119579212  229 DRVYWIDGENEAVYGANKFTGSELATLV-NNLNDAQDIIVYH 269
Cdd:pfam00058   1 GRLYWTDSSLRASISSADLNGSDRKTLFtDDLQHPNAIAVDP 42
 
Name Accession Description Interval E-value
Ldl_recept_b pfam00058
Low-density lipoprotein receptor repeat class B; This domain is also known as the YWTD motif ...
 142-182 1.77e-14

Low-density lipoprotein receptor repeat class B; This domain is also known as the YWTD motif after the most conserved region of the repeat. The YWTD repeat is found in multiple tandem repeats and has been predicted to form a beta-propeller structure.


Pssm-ID: 459654  Cd Length: 42  Bit Score: 67.18  E-value: 1.77e-14
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 119579212  142 GFVYWSDWGEPAKIEKAGMNGFDRRPLVTADIQWPNGITLD 182
Cdd:pfam00058   1 GRLYWTDSSLRASISSADLNGSDRKTLFTDDLQHPNAIAVD 41
LY smart00135
Low-density lipoprotein-receptor YWTD domain; Type "B" repeats in low-density lipoprotein (LDL) ...
 79-121 1.55e-10

Low-density lipoprotein-receptor YWTD domain; Type "B" repeats in low-density lipoprotein (LDL) receptor that plays a central role in mammalian cholesterol metabolism. Also present in a variety of molecules similar to gp300/megalin.


Pssm-ID: 214531 [Multi-domain]  Cd Length: 43  Bit Score: 56.07  E-value: 1.55e-10
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 119579212    79 HVKMIDNVYNPAAIAVDWVYKTIYWTDAASKTISVATLDGTKR 121
Cdd:smart00135   1 RTLLSSGLGHPNGLAVDWIEGRLYWTDWGLDVIEVANLDGTNR 43
Ldl_recept_b pfam00058
Low-density lipoprotein receptor repeat class B; This domain is also known as the YWTD motif ...
 101-139 6.19e-10

Low-density lipoprotein receptor repeat class B; This domain is also known as the YWTD motif after the most conserved region of the repeat. The YWTD repeat is found in multiple tandem repeats and has been predicted to form a beta-propeller structure.


Pssm-ID: 459654  Cd Length: 42  Bit Score: 54.09  E-value: 6.19e-10
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 119579212  101 IYWTDAASK-TISVATLDGTKRKFLFNSDLREPASIAVDP 139
Cdd:pfam00058   3 LYWTDSSLRaSISSADLNGSDRKTLFTDDLQHPNAIAVDP 42
FXa_inhibition pfam14670
Coagulation Factor Xa inhibitory site; This short domain on coagulation enzyme factor Xa is ...
 280-323 2.27e-09

Coagulation Factor Xa inhibitory site; This short domain on coagulation enzyme factor Xa is found to be the target for a potent inhibitor of coagulation, TAK-442.


Pssm-ID: 464251 [Multi-domain]  Cd Length: 36  Bit Score: 52.63  E-value: 2.27e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 119579212  280 CEEDmeNGGCEYLCLPAPQindhspKYTCSCPSGYNVEENGRDC 323
Cdd:pfam14670   1 CSVN--NGGCSHLCLNTPG------GYTCSCPEGYELQDDGRTC 36
LY smart00135
Low-density lipoprotein-receptor YWTD domain; Type "B" repeats in low-density lipoprotein (LDL) ...
 124-165 6.75e-09

Low-density lipoprotein-receptor YWTD domain; Type "B" repeats in low-density lipoprotein (LDL) receptor that plays a central role in mammalian cholesterol metabolism. Also present in a variety of molecules similar to gp300/megalin.


Pssm-ID: 214531 [Multi-domain]  Cd Length: 43  Bit Score: 51.45  E-value: 6.75e-09
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 119579212   124 LFNSDLREPASIAVDPLSGFVYWSDWGEPaKIEKAGMNGFDR 165
Cdd:smart00135   3 LLSSGLGHPNGLAVDWIEGRLYWTDWGLD-VIEVANLDGTNR 43
LY smart00135
Low-density lipoprotein-receptor YWTD domain; Type "B" repeats in low-density lipoprotein (LDL) ...
 166-208 1.96e-08

Low-density lipoprotein-receptor YWTD domain; Type "B" repeats in low-density lipoprotein (LDL) receptor that plays a central role in mammalian cholesterol metabolism. Also present in a variety of molecules similar to gp300/megalin.


Pssm-ID: 214531 [Multi-domain]  Cd Length: 43  Bit Score: 49.91  E-value: 1.96e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 119579212   166 RPLVTADIQWPNGITLDLIKSRLYWLDSKLHMLSSVDLNGQDR 208
Cdd:smart00135   1 RTLLSSGLGHPNGLAVDWIEGRLYWTDWGLDVIEVANLDGTNR 43
Ldl_recept_b pfam00058
Low-density lipoprotein receptor repeat class B; This domain is also known as the YWTD motif ...
 55-96 7.80e-08

Low-density lipoprotein receptor repeat class B; This domain is also known as the YWTD motif after the most conserved region of the repeat. The YWTD repeat is found in multiple tandem repeats and has been predicted to form a beta-propeller structure.


Pssm-ID: 459654  Cd Length: 42  Bit Score: 48.31  E-value: 7.80e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 119579212   55 QKLFWADLSQKA-IFSASIDDKVgRHVKMIDNVYNPAAIAVDW 96
Cdd:pfam00058   1 GRLYWTDSSLRAsISSADLNGSD-RKTLFTDDLQHPNAIAVDP 42
Ldl_recept_b pfam00058
Low-density lipoprotein receptor repeat class B; This domain is also known as the YWTD motif ...
 229-269 3.93e-07

Low-density lipoprotein receptor repeat class B; This domain is also known as the YWTD motif after the most conserved region of the repeat. The YWTD repeat is found in multiple tandem repeats and has been predicted to form a beta-propeller structure.


Pssm-ID: 459654  Cd Length: 42  Bit Score: 46.38  E-value: 3.93e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 119579212  229 DRVYWIDGENEAVYGANKFTGSELATLV-NNLNDAQDIIVYH 269
Cdd:pfam00058   1 GRLYWTDSSLRASISSADLNGSDRKTLFtDDLQHPNAIAVDP 42
Ldl_recept_b pfam00058
Low-density lipoprotein receptor repeat class B; This domain is also known as the YWTD motif ...
 187-228 7.65e-07

Low-density lipoprotein receptor repeat class B; This domain is also known as the YWTD motif after the most conserved region of the repeat. The YWTD repeat is found in multiple tandem repeats and has been predicted to form a beta-propeller structure.


Pssm-ID: 459654  Cd Length: 42  Bit Score: 45.61  E-value: 7.65e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 119579212  187 RLYWLDSKLH-MLSSVDLNGQDRRIVLKSLefLAHPLALTIFE 228
Cdd:pfam00058   2 RLYWTDSSLRaSISSADLNGSDRKTLFTDD--LQHPNAIAVDP 42
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
49-150 6.76e-05

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 44.30  E-value: 6.76e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119579212  49 DADIAAQKLFWADLSQKAIfsASIDDKVGRHVKMIDNVYNPAAIAVDWVYKTIYWTDAASKTISVatLDGTKRKFLFNSD 128
Cdd:COG3391   74 DAGADGRRLYVANSGSGRV--SVIDLATGKVVATIPVGGGPRGLAVDPDGGRLYVADSGNGRVSV--IDTATGKVVATIP 149

                         90       100
                 ....*....|....*....|...
gi 119579212 129 L-REPASIAVDPLSGFVYWSDWG 150
Cdd:COG3391  150 VgAGPHGIAVDPDGKRLYVANSG 172
NHL_like_6 cd14962
Uncharacterized NHL-repeat domain in bacterial proteins; The NHL (NCL-1, HT2A and LIN-41) ...
 45-148 2.90e-04

Uncharacterized NHL-repeat domain in bacterial proteins; The NHL (NCL-1, HT2A and LIN-41) repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures.


Pssm-ID: 271332 [Multi-domain]  Cd Length: 271  Bit Score: 42.57  E-value: 2.90e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119579212  45 TVALDADiaaQKLFWADLSQKAIFsasIDDKVGRHVKMIDN-----VYNPAAIAVDwVYKTIYWTDAASKTISVATLDGT 119
Cdd:cd14962   16 GVAADGR---GRIYVADTGRGAVF---VFDLPNGKVFVIGNagpnrFVSPIGVAID-ANGNLYVSDAELGKVFVFDRDGK 88

                         90       100       110
                 ....*....|....*....|....*....|
gi 119579212 120 KRKFLFNSDLRE-PASIAVDPLSGFVYWSD 148
Cdd:cd14962   89 FLRAIGAGALFKrPTGIAVDPAGKRLYVVD 118
 
Name Accession Description Interval E-value
Ldl_recept_b pfam00058
Low-density lipoprotein receptor repeat class B; This domain is also known as the YWTD motif ...
 142-182 1.77e-14

Low-density lipoprotein receptor repeat class B; This domain is also known as the YWTD motif after the most conserved region of the repeat. The YWTD repeat is found in multiple tandem repeats and has been predicted to form a beta-propeller structure.


Pssm-ID: 459654  Cd Length: 42  Bit Score: 67.18  E-value: 1.77e-14
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 119579212  142 GFVYWSDWGEPAKIEKAGMNGFDRRPLVTADIQWPNGITLD 182
Cdd:pfam00058   1 GRLYWTDSSLRASISSADLNGSDRKTLFTDDLQHPNAIAVD 41
LY smart00135
Low-density lipoprotein-receptor YWTD domain; Type "B" repeats in low-density lipoprotein (LDL) ...
 79-121 1.55e-10

Low-density lipoprotein-receptor YWTD domain; Type "B" repeats in low-density lipoprotein (LDL) receptor that plays a central role in mammalian cholesterol metabolism. Also present in a variety of molecules similar to gp300/megalin.


Pssm-ID: 214531 [Multi-domain]  Cd Length: 43  Bit Score: 56.07  E-value: 1.55e-10
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 119579212    79 HVKMIDNVYNPAAIAVDWVYKTIYWTDAASKTISVATLDGTKR 121
Cdd:smart00135   1 RTLLSSGLGHPNGLAVDWIEGRLYWTDWGLDVIEVANLDGTNR 43
Ldl_recept_b pfam00058
Low-density lipoprotein receptor repeat class B; This domain is also known as the YWTD motif ...
 101-139 6.19e-10

Low-density lipoprotein receptor repeat class B; This domain is also known as the YWTD motif after the most conserved region of the repeat. The YWTD repeat is found in multiple tandem repeats and has been predicted to form a beta-propeller structure.


Pssm-ID: 459654  Cd Length: 42  Bit Score: 54.09  E-value: 6.19e-10
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 119579212  101 IYWTDAASK-TISVATLDGTKRKFLFNSDLREPASIAVDP 139
Cdd:pfam00058   3 LYWTDSSLRaSISSADLNGSDRKTLFTDDLQHPNAIAVDP 42
FXa_inhibition pfam14670
Coagulation Factor Xa inhibitory site; This short domain on coagulation enzyme factor Xa is ...
 280-323 2.27e-09

Coagulation Factor Xa inhibitory site; This short domain on coagulation enzyme factor Xa is found to be the target for a potent inhibitor of coagulation, TAK-442.


Pssm-ID: 464251 [Multi-domain]  Cd Length: 36  Bit Score: 52.63  E-value: 2.27e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 119579212  280 CEEDmeNGGCEYLCLPAPQindhspKYTCSCPSGYNVEENGRDC 323
Cdd:pfam14670   1 CSVN--NGGCSHLCLNTPG------GYTCSCPEGYELQDDGRTC 36
LY smart00135
Low-density lipoprotein-receptor YWTD domain; Type "B" repeats in low-density lipoprotein (LDL) ...
 124-165 6.75e-09

Low-density lipoprotein-receptor YWTD domain; Type "B" repeats in low-density lipoprotein (LDL) receptor that plays a central role in mammalian cholesterol metabolism. Also present in a variety of molecules similar to gp300/megalin.


Pssm-ID: 214531 [Multi-domain]  Cd Length: 43  Bit Score: 51.45  E-value: 6.75e-09
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 119579212   124 LFNSDLREPASIAVDPLSGFVYWSDWGEPaKIEKAGMNGFDR 165
Cdd:smart00135   3 LLSSGLGHPNGLAVDWIEGRLYWTDWGLD-VIEVANLDGTNR 43
LY smart00135
Low-density lipoprotein-receptor YWTD domain; Type "B" repeats in low-density lipoprotein (LDL) ...
 166-208 1.96e-08

Low-density lipoprotein-receptor YWTD domain; Type "B" repeats in low-density lipoprotein (LDL) receptor that plays a central role in mammalian cholesterol metabolism. Also present in a variety of molecules similar to gp300/megalin.


Pssm-ID: 214531 [Multi-domain]  Cd Length: 43  Bit Score: 49.91  E-value: 1.96e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 119579212   166 RPLVTADIQWPNGITLDLIKSRLYWLDSKLHMLSSVDLNGQDR 208
Cdd:smart00135   1 RTLLSSGLGHPNGLAVDWIEGRLYWTDWGLDVIEVANLDGTNR 43
Ldl_recept_b pfam00058
Low-density lipoprotein receptor repeat class B; This domain is also known as the YWTD motif ...
 55-96 7.80e-08

Low-density lipoprotein receptor repeat class B; This domain is also known as the YWTD motif after the most conserved region of the repeat. The YWTD repeat is found in multiple tandem repeats and has been predicted to form a beta-propeller structure.


Pssm-ID: 459654  Cd Length: 42  Bit Score: 48.31  E-value: 7.80e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 119579212   55 QKLFWADLSQKA-IFSASIDDKVgRHVKMIDNVYNPAAIAVDW 96
Cdd:pfam00058   1 GRLYWTDSSLRAsISSADLNGSD-RKTLFTDDLQHPNAIAVDP 42
Ldl_recept_b pfam00058
Low-density lipoprotein receptor repeat class B; This domain is also known as the YWTD motif ...
 229-269 3.93e-07

Low-density lipoprotein receptor repeat class B; This domain is also known as the YWTD motif after the most conserved region of the repeat. The YWTD repeat is found in multiple tandem repeats and has been predicted to form a beta-propeller structure.


Pssm-ID: 459654  Cd Length: 42  Bit Score: 46.38  E-value: 3.93e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 119579212  229 DRVYWIDGENEAVYGANKFTGSELATLV-NNLNDAQDIIVYH 269
Cdd:pfam00058   1 GRLYWTDSSLRASISSADLNGSDRKTLFtDDLQHPNAIAVDP 42
Ldl_recept_b pfam00058
Low-density lipoprotein receptor repeat class B; This domain is also known as the YWTD motif ...
 187-228 7.65e-07

Low-density lipoprotein receptor repeat class B; This domain is also known as the YWTD motif after the most conserved region of the repeat. The YWTD repeat is found in multiple tandem repeats and has been predicted to form a beta-propeller structure.


Pssm-ID: 459654  Cd Length: 42  Bit Score: 45.61  E-value: 7.65e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 119579212  187 RLYWLDSKLH-MLSSVDLNGQDRRIVLKSLefLAHPLALTIFE 228
Cdd:pfam00058   2 RLYWTDSSLRaSISSADLNGSDRKTLFTDD--LQHPNAIAVDP 42
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
49-150 6.76e-05

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 44.30  E-value: 6.76e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119579212  49 DADIAAQKLFWADLSQKAIfsASIDDKVGRHVKMIDNVYNPAAIAVDWVYKTIYWTDAASKTISVatLDGTKRKFLFNSD 128
Cdd:COG3391   74 DAGADGRRLYVANSGSGRV--SVIDLATGKVVATIPVGGGPRGLAVDPDGGRLYVADSGNGRVSV--IDTATGKVVATIP 149

                         90       100
                 ....*....|....*....|...
gi 119579212 129 L-REPASIAVDPLSGFVYWSDWG 150
Cdd:COG3391  150 VgAGPHGIAVDPDGKRLYVANSG 172
NHL_like_6 cd14962
Uncharacterized NHL-repeat domain in bacterial proteins; The NHL (NCL-1, HT2A and LIN-41) ...
 45-148 2.90e-04

Uncharacterized NHL-repeat domain in bacterial proteins; The NHL (NCL-1, HT2A and LIN-41) repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures.


Pssm-ID: 271332 [Multi-domain]  Cd Length: 271  Bit Score: 42.57  E-value: 2.90e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119579212  45 TVALDADiaaQKLFWADLSQKAIFsasIDDKVGRHVKMIDN-----VYNPAAIAVDwVYKTIYWTDAASKTISVATLDGT 119
Cdd:cd14962   16 GVAADGR---GRIYVADTGRGAVF---VFDLPNGKVFVIGNagpnrFVSPIGVAID-ANGNLYVSDAELGKVFVFDRDGK 88

                         90       100       110
                 ....*....|....*....|....*....|
gi 119579212 120 KRKFLFNSDLRE-PASIAVDPLSGFVYWSD 148
Cdd:cd14962   89 FLRAIGAGALFKrPTGIAVDPAGKRLYVVD 118
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
99-246 5.99e-04

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 41.22  E-value: 5.99e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119579212  99 KTIYWTDAASKTISVatLDGTKRKFLFNSDL-REPASIAVDPLSGFVYWSDWGEPA--KIEKAGMNgfdrrplVTADIQ- 174
Cdd:COG3391   80 RRLYVANSGSGRVSV--IDLATGKVVATIPVgGGPRGLAVDPDGGRLYVADSGNGRvsVIDTATGK-------VVATIPv 150

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119579212 175 --WPNGITLDLIKSRLYWLDSKLHMLS---SVdLNGQDRRiVLKSLEFLAHPLALTIFED--RVYWID-GENEAVYGANK 246
Cdd:COG3391  151 gaGPHGIAVDPDGKRLYVANSGSNTVSvivSV-IDTATGK-VVATIPVGGGPVGVAVSPDgrRLYVANrGSNTSNGGSNT 228
NHL_like_5 cd14963
Uncharacterized NHL-repeat domain in bacterial proteins; The NHL (NCL-1, HT2A and LIN-41) ...
 89-255 1.18e-03

Uncharacterized NHL-repeat domain in bacterial proteins; The NHL (NCL-1, HT2A and LIN-41) repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures.


Pssm-ID: 271333 [Multi-domain]  Cd Length: 268  Bit Score: 40.74  E-value: 1.18e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119579212  89 PAAIAVDWVYKtIYWTDAASKTISVATLDGTKRKFLFNSDLRE----PASIAVDplSGFVYWSDWG---------EPAKI 155
Cdd:cd14963   58 PYGIAVDSDGN-IYVADLYNGRIQVFDPDGKFLKYFPEKKDRVklisPAGLAID--DGKLYVSDVKkhkvivfdlEGKLL 134

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119579212 156 EKAGMNGFDRrplvtADIQWPNGITLDLiKSRLYWLDSKLHMLSSVDLNGQDRRIVLKS---LEFLAHPLALTIFED-RV 231
Cdd:cd14963  135 LEFGKPGSEP-----GELSYPNGIAVDE-DGNIYVADSGNGRIQVFDKNGKFIKELNGSpdgKSGFVNPRGIAVDPDgNL 208

                        170       180
                 ....*....|....*....|....
gi 119579212 232 YWIDGENEAVYGANKfTGSELATL 255
Cdd:cd14963  209 YVVDNLSHRVYVFDE-QGKELFTF 231
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
17-150 1.43e-03

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 40.06  E-value: 1.43e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119579212  17 LIFTNRRD--IRKIGLERKEYIQLVEQLRNTVALDADIAAQKLFWADLSQKAIFSasIDDKVGRHVKMIDNVYNPAAIAV 94
Cdd:COG3391   82 LYVANSGSgrVSVIDLATGKVVATIPVGGGPRGLAVDPDGGRLYVADSGNGRVSV--IDTATGKVVATIPVGAGPHGIAV 159

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 119579212  95 DWVYKTIYWTDAASKTIS--VATLDGTKRKFLFNSDLRE-PASIAVDPLSGFVYWSDWG 150
Cdd:COG3391  160 DPDGKRLYVANSGSNTVSviVSVIDTATGKVVATIPVGGgPVGVAVSPDGRRLYVANRG 218
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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