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Conserved domains on  [gi|119603206|gb|EAW82800|]
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hCG1644478 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Mpp10 super family cl47859
Mpp10 protein; This family includes proteins related to Mpp10 (M phase phosphoprotein 10). The ...
 27-97 6.64e-08

Mpp10 protein; This family includes proteins related to Mpp10 (M phase phosphoprotein 10). The U3 small nucleolar ribonucleoprotein (snoRNP) is required for three cleavage events that generate the mature 18S rRNA from the pre-rRNA. In Saccharomyces cerevisiae, depletion of Mpp10, a U3 snoRNP-specific protein, halts 18S rRNA production and impairs cleavage at the three U3 snoRNP-dependent sites.


The actual alignment was detected with superfamily member pfam04006:

Pssm-ID: 461128 [Multi-domain]  Cd Length: 506  Bit Score: 49.19  E-value: 6.64e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 119603206   27 SDEDSDLDFDISKLEQQSKVQNTGHGKprekSIIDEKFFQLSEMEAYLENREKEEERKDDNDDEVEDTDFF 97
Cdd:pfam04006 130 SDDEGLEEEDVKELEQKTKKDAKKGRK----SVVDDKFFKLDEMEKFLEDEEKKEERKDKGKEDEDDIDYF 196
 
Name Accession Description Interval E-value
Mpp10 pfam04006
Mpp10 protein; This family includes proteins related to Mpp10 (M phase phosphoprotein 10). The ...
 27-97 6.64e-08

Mpp10 protein; This family includes proteins related to Mpp10 (M phase phosphoprotein 10). The U3 small nucleolar ribonucleoprotein (snoRNP) is required for three cleavage events that generate the mature 18S rRNA from the pre-rRNA. In Saccharomyces cerevisiae, depletion of Mpp10, a U3 snoRNP-specific protein, halts 18S rRNA production and impairs cleavage at the three U3 snoRNP-dependent sites.


Pssm-ID: 461128 [Multi-domain]  Cd Length: 506  Bit Score: 49.19  E-value: 6.64e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 119603206   27 SDEDSDLDFDISKLEQQSKVQNTGHGKprekSIIDEKFFQLSEMEAYLENREKEEERKDDNDDEVEDTDFF 97
Cdd:pfam04006 130 SDDEGLEEEDVKELEQKTKKDAKKGRK----SVVDDKFFKLDEMEKFLEDEEKKEERKDKGKEDEDDIDYF 196
 
Name Accession Description Interval E-value
Mpp10 pfam04006
Mpp10 protein; This family includes proteins related to Mpp10 (M phase phosphoprotein 10). The ...
 27-97 6.64e-08

Mpp10 protein; This family includes proteins related to Mpp10 (M phase phosphoprotein 10). The U3 small nucleolar ribonucleoprotein (snoRNP) is required for three cleavage events that generate the mature 18S rRNA from the pre-rRNA. In Saccharomyces cerevisiae, depletion of Mpp10, a U3 snoRNP-specific protein, halts 18S rRNA production and impairs cleavage at the three U3 snoRNP-dependent sites.


Pssm-ID: 461128 [Multi-domain]  Cd Length: 506  Bit Score: 49.19  E-value: 6.64e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 119603206   27 SDEDSDLDFDISKLEQQSKVQNTGHGKprekSIIDEKFFQLSEMEAYLENREKEEERKDDNDDEVEDTDFF 97
Cdd:pfam04006 130 SDDEGLEEEDVKELEQKTKKDAKKGRK----SVVDDKFFKLDEMEKFLEDEEKKEERKDKGKEDEDDIDYF 196
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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