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Conserved domains on  [gi|119608720|gb|EAW88314|]
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F-box and WD-40 domain protein 5, isoform CRA_f [Homo sapiens]

Protein Classification

WD40 repeat domain-containing protein( domain architecture ID 1000017)

WD40 repeat domain-containing protein folds into a beta-propeller structure and functions as a scaffold, providing a platform for the interaction and assembly of several proteins into a signalosome; similar to a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly

CATH:  2.130.10.10
Gene Ontology:  GO:0005515
PubMed:  10322433|8090199|30069656|29026209
SCOP:  4002744

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
WD40 super family cl29593
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 73-164 1.02e-10

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


The actual alignment was detected with superfamily member cd00200:

Pssm-ID: 475233 [Multi-domain]  Cd Length: 289  Bit Score: 59.27  E-value: 1.02e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119608720  73 VFDLKTmREVRRALRAHRAYtpndeCFFIFLDVSRDFVASGAEDRHGYIWDRHYNICLARLR-HEDVVNSVVFSPQEQEl 151
Cdd:cd00200  119 VWDVET-GKCLTTLRGHTDW-----VNSVAFSPDGTFVASSSQDGTIKLWDLRTGKCVATLTgHTGEVNSVAFSPDGEK- 191

                         90
                 ....*....|...
gi 119608720 152 LLTASDDATIKAW 164
Cdd:cd00200  192 LLSSSSDGTIKLW 204
 
Name Accession Description Interval E-value
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 73-164 1.02e-10

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 59.27  E-value: 1.02e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119608720  73 VFDLKTmREVRRALRAHRAYtpndeCFFIFLDVSRDFVASGAEDRHGYIWDRHYNICLARLR-HEDVVNSVVFSPQEQEl 151
Cdd:cd00200  119 VWDVET-GKCLTTLRGHTDW-----VNSVAFSPDGTFVASSSQDGTIKLWDLRTGKCVATLTgHTGEVNSVAFSPDGEK- 191

                         90
                 ....*....|...
gi 119608720 152 LLTASDDATIKAW 164
Cdd:cd00200  192 LLSSSSDGTIKLW 204
WD40 COG2319
WD40 repeat [General function prediction only];
73-165 2.77e-10

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 58.38  E-value: 2.77e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119608720  73 VFDLKTmREVRRALRAHR------AYTPNDEcffifldvsrdFVASGAEDRHGYIWDRHYNICLARLR-HEDVVNSVVFS 145
Cdd:COG2319  314 LWDLAT-GKLLRTLTGHTgavrsvAFSPDGK-----------TLASGSDDGTVRLWDLATGELLRTLTgHTGAVTSVAFS 381

                         90       100
                 ....*....|....*....|
gi 119608720 146 PQEQeLLLTASDDATIKAWR 165
Cdd:COG2319  382 PDGR-TLASGSADGTVRLWD 400
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 129-164 1.53e-04

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 37.68  E-value: 1.53e-04
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 119608720   129 CLARLR-HEDVVNSVVFSPQEQeLLLTASDDATIKAW 164
Cdd:smart00320   4 LLKTLKgHTGPVTSVAFSPDGK-YLASGSDDGTIKLW 39
WD40 pfam00400
WD domain, G-beta repeat;
129-164 4.75e-04

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 36.55  E-value: 4.75e-04
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 119608720  129 CLARLR-HEDVVNSVVFSPQEQeLLLTASDDATIKAW 164
Cdd:pfam00400   3 LLKTLEgHTGSVTSLAFSPDGK-LLASGSDDGTVKVW 38
 
Name Accession Description Interval E-value
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 73-164 1.02e-10

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 59.27  E-value: 1.02e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119608720  73 VFDLKTmREVRRALRAHRAYtpndeCFFIFLDVSRDFVASGAEDRHGYIWDRHYNICLARLR-HEDVVNSVVFSPQEQEl 151
Cdd:cd00200  119 VWDVET-GKCLTTLRGHTDW-----VNSVAFSPDGTFVASSSQDGTIKLWDLRTGKCVATLTgHTGEVNSVAFSPDGEK- 191

                         90
                 ....*....|...
gi 119608720 152 LLTASDDATIKAW 164
Cdd:cd00200  192 LLSSSSDGTIKLW 204
WD40 COG2319
WD40 repeat [General function prediction only];
73-165 2.77e-10

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 58.38  E-value: 2.77e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119608720  73 VFDLKTmREVRRALRAHR------AYTPNDEcffifldvsrdFVASGAEDRHGYIWDRHYNICLARLR-HEDVVNSVVFS 145
Cdd:COG2319  314 LWDLAT-GKLLRTLTGHTgavrsvAFSPDGK-----------TLASGSDDGTVRLWDLATGELLRTLTgHTGAVTSVAFS 381

                         90       100
                 ....*....|....*....|
gi 119608720 146 PQEQeLLLTASDDATIKAWR 165
Cdd:COG2319  382 PDGR-TLASGSADGTVRLWD 400
WD40 COG2319
WD40 repeat [General function prediction only];
73-189 7.71e-10

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 57.23  E-value: 7.71e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119608720  73 VFDLKTMREVRRaLRAHRAYtpndecfFIFLDVSRD--FVASGAEDRHGYIWDRHYNICLARLR-HEDVVNSVVFSPQEQ 149
Cdd:COG2319  230 LWDLATGKLLRT-LTGHSGS-------VRSVAFSPDgrLLASGSADGTVRLWDLATGELLRTLTgHSGGVNSVAFSPDGK 301

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 119608720 150 eLLLTASDDATIKAW--RSPRTMRVLQAPRPRPRTF-FS----WLAS 189
Cdd:COG2319  302 -LLASGSDDGTVRLWdlATGKLLRTLTGHTGAVRSVaFSpdgkTLAS 347
WD40 COG2319
WD40 repeat [General function prediction only];
27-189 7.93e-09

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 54.15  E-value: 7.93e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119608720  27 IHGH---IIGMGLSPDNRYLYVNSRawpNGAVvadpmqpppiaeeidlLVFDLKTMREVRRaLRAHR------AYTPNDE 97
Cdd:COG2319  158 LTGHsgaVTSVAFSPDGKLLASGSD---DGTV----------------RLWDLATGKLLRT-LTGHTgavrsvAFSPDGK 217

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119608720  98 cffifldvsrdFVASGAEDRHGYIWDRHYNICLARLR-HEDVVNSVVFSPQEQeLLLTASDDATIKAWR--SPRTMRVLQ 174
Cdd:COG2319  218 -----------LLASGSADGTVRLWDLATGKLLRTLTgHSGSVRSVAFSPDGR-LLASGSADGTVRLWDlaTGELLRTLT 285

                        170       180
                 ....*....|....*....|
gi 119608720 175 APRPRPRTF-FS----WLAS 189
Cdd:COG2319  286 GHSGGVNSVaFSpdgkLLAS 305
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 73-165 2.92e-08

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 52.34  E-value: 2.92e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119608720  73 VFDLKTMREVRRaLRAHraytpNDECFFIFLDVSRDFVASGAEDRHGYIWDRHYNICLARLR-HEDVVNSVVFSPQEQeL 151
Cdd:cd00200  203 LWDLSTGKCLGT-LRGH-----ENGVNSVAFSPDGYLLASGSEDGTIRVWDLRTGECVQTLSgHTNSVTSLAWSPDGK-R 275

                         90
                 ....*....|....
gi 119608720 152 LLTASDDATIKAWR 165
Cdd:cd00200  276 LASGSADGTIRIWD 289
WD40 COG2319
WD40 repeat [General function prediction only];
103-189 3.40e-08

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 52.22  E-value: 3.40e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119608720 103 LDVSRD--FVASGAEDRHGYIWDRHYNICLARLR-HEDVVNSVVFSPQEQeLLLTASDDATIKAW--RSPRTMRVLQAPR 177
Cdd:COG2319  126 VAFSPDgkTLASGSADGTVRLWDLATGKLLRTLTgHSGAVTSVAFSPDGK-LLASGSDDGTVRLWdlATGKLLRTLTGHT 204

                         90
                 ....*....|....*..
gi 119608720 178 PRPRTF-FS----WLAS 189
Cdd:COG2319  205 GAVRSVaFSpdgkLLAS 221
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 83-164 4.53e-08

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 51.57  E-value: 4.53e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119608720  83 RRALRAHRaytpnDECFFIFLDVSRDFVASGAEDRHGYIWDRHYNICLARLR-HEDVVNSVVFSPQeQELLLTASDDATI 161
Cdd:cd00200    2 RRTLKGHT-----GGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTLKgHTGPVRDVAASAD-GTYLASGSSDKTI 75


                 ...
gi 119608720 162 KAW 164
Cdd:cd00200   76 RLW 78
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 73-179 5.38e-08

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 51.57  E-value: 5.38e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119608720  73 VFDLKTMREVRRaLRAHraytpNDECFFIFLDVSRDFVASGAEDRHGYIWDRHYNICLARLR-HEDVVNSVVFSPQeQEL 151
Cdd:cd00200  161 LWDLRTGKCVAT-LTGH-----TGEVNSVAFSPDGEKLLSSSSDGTIKLWDLSTGKCLGTLRgHENGVNSVAFSPD-GYL 233

                         90       100       110
                 ....*....|....*....|....*....|
gi 119608720 152 LLTASDDATIKAW--RSPRTMRVLQAPRPR 179
Cdd:cd00200  234 LASGSEDGTIRVWdlRTGECVQTLSGHTNS 263
WD40 COG2319
WD40 repeat [General function prediction only];
110-189 3.02e-07

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 49.52  E-value: 3.02e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119608720 110 VASGAEDRHGYIWDRHYNICLARLR-HEDVVNSVVFSPQEQeLLLTASDDATIKAW--RSPRTMRVLQAPRPRPRTF-FS 185
Cdd:COG2319   93 LASASADGTVRLWDLATGLLLRTLTgHTGAVRSVAFSPDGK-TLASGSADGTVRLWdlATGKLLRTLTGHSGAVTSVaFS 171


                 ....*...
gi 119608720 186 ----WLAS 189
Cdd:COG2319  172 pdgkLLAS 179
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 23-164 8.23e-07

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 48.10  E-value: 8.23e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119608720  23 HVIDIHGHII-GMGLSPDNRYLYVNSRawpNGAVvadpmqpppiaeeidlLVFDLKTMREVRRaLRAHraytpNDECFFI 101
Cdd:cd00200    3 RTLKGHTGGVtCVAFSPDGKLLATGSG---DGTI----------------KVWDLETGELLRT-LKGH-----TGPVRDV 57

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 119608720 102 FLDVSRDFVASGAEDRHGYIWDRHYNICLARLR-HEDVVNSVVFSPQEQeLLLTASDDATIKAW 164
Cdd:cd00200   58 AASADGTYLASGSSDKTIRLWDLETGECVRTLTgHTSYVSSVAFSPDGR-ILSSSSRDKTIKVW 120
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 129-164 1.53e-04

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 37.68  E-value: 1.53e-04
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 119608720   129 CLARLR-HEDVVNSVVFSPQEQeLLLTASDDATIKAW 164
Cdd:smart00320   4 LLKTLKgHTGPVTSVAFSPDGK-YLASGSDDGTIKLW 39
WD40 pfam00400
WD domain, G-beta repeat;
129-164 4.75e-04

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 36.55  E-value: 4.75e-04
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 119608720  129 CLARLR-HEDVVNSVVFSPQEQeLLLTASDDATIKAW 164
Cdd:pfam00400   3 LLKTLEgHTGSVTSLAFSPDGK-LLASGSDDGTVKVW 38
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 135-165 2.39e-03

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 37.70  E-value: 2.39e-03
                         10        20        30
                 ....*....|....*....|....*....|.
gi 119608720 135 HEDVVNSVVFSPQeQELLLTASDDATIKAWR 165
Cdd:cd00200    8 HTGGVTCVAFSPD-GKLLATGSGDGTIKVWD 37
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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