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Conserved domains on  [gi|119612407|gb|EAW92001|]
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collagen, type XIV, alpha 1 (undulin), isoform CRA_d, partial [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 214-299 1.57e-14

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


:

Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 69.45  E-value: 1.57e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407 214 SPPRNLRISNVGSNSARLTWDP---TSRQINGYRIVYNNADGTEINEVEVDPI--TTFPLKGLTPLTEYTIAIFSIYDEG 288
Cdd:cd00063    2 SPPTNLRVTDVTSTSVTLSWTPpedDGGPITGYVVEYREKGSGDWKEVEVTPGseTSYTLTGLKPGTEYEFRVRAVNGGG 81

                         90
                 ....*....|..
gi 119612407 289 QSEPLTGV-FTT 299
Cdd:cd00063   82 ESPPSESVtVTT 93
FN3 super family cl27307
Fibronectin type 3 domain [General function prediction only];
74-459 5.83e-14

Fibronectin type 3 domain [General function prediction only];


The actual alignment was detected with superfamily member COG3401:

Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 75.42  E-value: 5.83e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407  74 DEVVVDGTVSSTVLKNLMSLTEYQIAVFAI---YAHTASEGLRGTETTLALPMASDLLLYDVTENSMRVKWDAVP--GAS 148
Cdd:COG3401  183 TSLTVTSTTLVDGGGDIEPGTTYYYRVAATdtgGESAPSNEVSVTTPTTPPSAPTGLTATADTPGSVTLSWDPVTesDAT 262

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407 149 GYLILYAPlteglAGDEKEMKIGE-THTDIELSGLLPNTEYTVTVYAM--FGEE--ASDPVTGQETTLALSPPRNLRISN 223
Cdd:COG3401  263 GYRVYRSN-----SGDGPFTKVATvTTTSYTDTGLTNGTTYYYRVTAVdaAGNEsaPSNVVSVTTDLTPPAAPSGLTATA 337

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407 224 VGSNSARLTWDP-TSRQINGYRIVYNNADGTEINEV-EVDPITTFPLKGLTPLTEYTIAIFSIYDEG----QSEPLTGVF 297
Cdd:COG3401  338 VGSSSITLSWTAsSDADVTGYNVYRSTSGGGTYTKIaETVTTTSYTDTGLTPGTTYYYKVTAVDAAGnesaPSEEVSATT 417

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407 298 TTEEVPAQQYLEIDEVTTDSFRVTWHPLSADEGLHKLMWIPVYGGKTEEVVLKEEQDSHVIEGLEPGTEYEVSLLAVLDD 377
Cdd:COG3401  418 ASAASGESLTASVDAVPLTDVAGATAAASAASNPGVSAAVLADGGDTGNAVPFTTTSSTVTATTTDTTTANLSVTTGSLV 497

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407 378 GSESEVVTAVGTTLDSFWTEPATTIVPTTSVTSVFQTGIRNLV-VGDETTSSLRVKWDISDSDVQQFRVTYMTAQGDPEE 456
Cdd:COG3401  498 GGSGASSVTNSVSVIGASAAAAVGGAPDGTPNVTGASPVTVGAsTGDVLITDLVSLTTSASSSVSGAGLGSGNLYLITTL 577


                 ...
gi 119612407 457 EVI 459
Cdd:COG3401  578 GGS 580
fn3 pfam00041
Fibronectin type III domain;
510-579 1.34e-11

Fibronectin type III domain;


:

Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 60.89  E-value: 1.34e-11
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 119612407  510 PQNLRVSEEWYNRLRITWDPP---SSPVKGYRIVYKPVSVPGPTLETFVGADINTILITNLLSGMDYNVKIFA 579
Cdd:pfam00041   3 PSNLTVTDVTSTSLTVSWTPPpdgNGPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQA 75
fn3 pfam00041
Fibronectin type III domain;
32-110 6.56e-10

Fibronectin type III domain;


:

Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 56.27  E-value: 6.56e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407   32 GPPTELITSEVTARSFMVNWTHAP---GNVEKYRVVYYPTRGGKPD-EVVVDGTVSSTVLKNLMSLTEYQIAVFAIYAHT 107
Cdd:pfam00041   1 SAPSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGEPWnEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80


                  ...
gi 119612407  108 ASE 110
Cdd:pfam00041  81 EGP 83
FN3 super family cl21522
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 600-675 2.71e-04

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


The actual alignment was detected with superfamily member pfam00041:

Pssm-ID: 473895 [Multi-domain]  Cd Length: 85  Bit Score: 40.09  E-value: 2.71e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407  600 VTNLQAKHVEMTSLCAHWQ----VHRHATAYRVVIESLQD-RQKQESTVGGGTTRHCFYGLQPDSEYKISVYTKLQEIEG 674
Cdd:pfam00041   3 PSNLTVTDVTSTSLTVSWTpppdGNGPITGYEVEYRPKNSgEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGGEG 82


                  .
gi 119612407  675 P 675
Cdd:pfam00041  83 P 83
 
Name Accession Description Interval E-value
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 214-299 1.57e-14

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 69.45  E-value: 1.57e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407 214 SPPRNLRISNVGSNSARLTWDP---TSRQINGYRIVYNNADGTEINEVEVDPI--TTFPLKGLTPLTEYTIAIFSIYDEG 288
Cdd:cd00063    2 SPPTNLRVTDVTSTSVTLSWTPpedDGGPITGYVVEYREKGSGDWKEVEVTPGseTSYTLTGLKPGTEYEFRVRAVNGGG 81

                         90
                 ....*....|..
gi 119612407 289 QSEPLTGV-FTT 299
Cdd:cd00063   82 ESPPSESVtVTT 93
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
74-459 5.83e-14

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 75.42  E-value: 5.83e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407  74 DEVVVDGTVSSTVLKNLMSLTEYQIAVFAI---YAHTASEGLRGTETTLALPMASDLLLYDVTENSMRVKWDAVP--GAS 148
Cdd:COG3401  183 TSLTVTSTTLVDGGGDIEPGTTYYYRVAATdtgGESAPSNEVSVTTPTTPPSAPTGLTATADTPGSVTLSWDPVTesDAT 262

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407 149 GYLILYAPlteglAGDEKEMKIGE-THTDIELSGLLPNTEYTVTVYAM--FGEE--ASDPVTGQETTLALSPPRNLRISN 223
Cdd:COG3401  263 GYRVYRSN-----SGDGPFTKVATvTTTSYTDTGLTNGTTYYYRVTAVdaAGNEsaPSNVVSVTTDLTPPAAPSGLTATA 337

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407 224 VGSNSARLTWDP-TSRQINGYRIVYNNADGTEINEV-EVDPITTFPLKGLTPLTEYTIAIFSIYDEG----QSEPLTGVF 297
Cdd:COG3401  338 VGSSSITLSWTAsSDADVTGYNVYRSTSGGGTYTKIaETVTTTSYTDTGLTPGTTYYYKVTAVDAAGnesaPSEEVSATT 417

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407 298 TTEEVPAQQYLEIDEVTTDSFRVTWHPLSADEGLHKLMWIPVYGGKTEEVVLKEEQDSHVIEGLEPGTEYEVSLLAVLDD 377
Cdd:COG3401  418 ASAASGESLTASVDAVPLTDVAGATAAASAASNPGVSAAVLADGGDTGNAVPFTTTSSTVTATTTDTTTANLSVTTGSLV 497

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407 378 GSESEVVTAVGTTLDSFWTEPATTIVPTTSVTSVFQTGIRNLV-VGDETTSSLRVKWDISDSDVQQFRVTYMTAQGDPEE 456
Cdd:COG3401  498 GGSGASSVTNSVSVIGASAAAAVGGAPDGTPNVTGASPVTVGAsTGDVLITDLVSLTTSASSSVSGAGLGSGNLYLITTL 577


                 ...
gi 119612407 457 EVI 459
Cdd:COG3401  578 GGS 580
fn3 pfam00041
Fibronectin type III domain;
214-292 2.00e-12

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 63.20  E-value: 2.00e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407  214 SPPRNLRISNVGSNSARLTWDP---TSRQINGYRIVYNNADGTEI-NEVEVDP-ITTFPLKGLTPLTEYTIAIFSIYDEG 288
Cdd:pfam00041   1 SAPSNLTVTDVTSTSLTVSWTPppdGNGPITGYEVEYRPKNSGEPwNEITVPGtTTSVTLTGLKPGTEYEVRVQAVNGGG 80


                  ....
gi 119612407  289 QSEP 292
Cdd:pfam00041  81 EGPP 84
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 214-290 1.23e-11

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 61.09  E-value: 1.23e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407   214 SPPRNLRISNVGSNSARLTWDPTSRQIN-----GYRIVYNNADGTEINEVEVDPITTFPLKGLTPLTEYTIAIFSIYDEG 288
Cdd:smart00060   2 SPPSNLRVTDVTSTSVTLSWEPPPDDGItgyivGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAG 81


                   ..
gi 119612407   289 QS 290
Cdd:smart00060  82 EG 83
fn3 pfam00041
Fibronectin type III domain;
510-579 1.34e-11

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 60.89  E-value: 1.34e-11
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 119612407  510 PQNLRVSEEWYNRLRITWDPP---SSPVKGYRIVYKPVSVPGPTLETFVGADINTILITNLLSGMDYNVKIFA 579
Cdd:pfam00041   3 PSNLTVTDVTSTSLTVSWTPPpdgNGPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQA 75
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 508-590 2.03e-10

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 57.89  E-value: 2.03e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407 508 SGPQNLRVSEEWYNRLRITWDPPS---SPVKGYRIVYKPVSVPGPTLETFVGADINTILITNLLSGMDYNVKIFASQASG 584
Cdd:cd00063    2 SPPTNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGG 81


                 ....*.
gi 119612407 585 FSDALT 590
Cdd:cd00063   82 ESPPSE 87
fn3 pfam00041
Fibronectin type III domain;
32-110 6.56e-10

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 56.27  E-value: 6.56e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407   32 GPPTELITSEVTARSFMVNWTHAP---GNVEKYRVVYYPTRGGKPD-EVVVDGTVSSTVLKNLMSLTEYQIAVFAIYAHT 107
Cdd:pfam00041   1 SAPSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGEPWnEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80


                  ...
gi 119612407  108 ASE 110
Cdd:pfam00041  81 EGP 83
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 32-110 1.40e-08

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 52.50  E-value: 1.40e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407  32 GPPTELITSEVTARSFMVNWTHAP---GNVEKYRVVYYPTRGGKPDEV-VVDGTVSSTVLKNLMSLTEYQIAVFAIYAHT 107
Cdd:cd00063    2 SPPTNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDWKEVeVTPGSETSYTLTGLKPGTEYEFRVRAVNGGG 81


                 ...
gi 119612407 108 ASE 110
Cdd:cd00063   82 ESP 84
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 125-194 2.05e-08

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 51.85  E-value: 2.05e-08
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 119612407   125 SDLLLYDVTENSMRVKWDAV--PGASGYLILYAPLTEGLAGDEKEMKIGETHTDIELSGLLPNTEYTVTVYA 194
Cdd:smart00060   5 SNLRVTDVTSTSVTLSWEPPpdDGITGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRA 76
fn3 pfam00041
Fibronectin type III domain;
125-194 8.09e-08

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 50.11  E-value: 8.09e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 119612407  125 SDLLLYDVTENSMRVKWDAVPGASG----YLILYAPLTEGlaGDEKEMKIGETHTDIELSGLLPNTEYTVTVYA 194
Cdd:pfam00041   4 SNLTVTDVTSTSLTVSWTPPPDGNGpitgYEVEYRPKNSG--EPWNEITVPGTTTSVTLTGLKPGTEYEVRVQA 75
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 308-390 2.94e-07

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 49.03  E-value: 2.94e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407 308 LEIDEVTTDSFRVTWHPLSADEGLH---KLMWIPVYGGKTEEVVLKEEQD-SHVIEGLEPGTEYEVSLLAVLDDGSESEV 383
Cdd:cd00063    7 LRVTDVTSTSVTLSWTPPEDDGGPItgyVVEYREKGSGDWKEVEVTPGSEtSYTLTGLKPGTEYEFRVRAVNGGGESPPS 86


                 ....*..
gi 119612407 384 VTAVGTT 390
Cdd:cd00063   87 ESVTVTT 93
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 508-586 5.48e-07

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 47.99  E-value: 5.48e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407   508 SGPQNLRVSEEWYNRLRITWDPPSSP-VKGYRIVYKPVSVPGPTLETFVGADI--NTILITNLLSGMDYNVKIFASQASG 584
Cdd:smart00060   2 SPPSNLRVTDVTSTSVTLSWEPPPDDgITGYIVGYRVEYREEGSEWKEVNVTPssTSYTLTGLKPGTEYEFRVRAVNGAG 81


                   ..
gi 119612407   585 FS 586
Cdd:smart00060  82 EG 83
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 32-109 8.42e-07

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 47.22  E-value: 8.42e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407    32 GPPTELITSEVTARSFMVNWTH-APGNVEKYRVVYYPTRGGKPD---EVVVDGTVSSTVLKNLMSLTEYQIAVFAIYAHT 107
Cdd:smart00060   2 SPPSNLRVTDVTSTSVTLSWEPpPDDGITGYIVGYRVEYREEGSewkEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAG 81


                   ..
gi 119612407   108 AS 109
Cdd:smart00060  82 EG 83
fn3 pfam00041
Fibronectin type III domain;
600-675 2.71e-04

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 40.09  E-value: 2.71e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407  600 VTNLQAKHVEMTSLCAHWQ----VHRHATAYRVVIESLQD-RQKQESTVGGGTTRHCFYGLQPDSEYKISVYTKLQEIEG 674
Cdd:pfam00041   3 PSNLTVTDVTSTSLTVSWTpppdGNGPITGYEVEYRPKNSgEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGGEG 82


                  .
gi 119612407  675 P 675
Cdd:pfam00041  83 P 83
 
Name Accession Description Interval E-value
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 214-299 1.57e-14

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 69.45  E-value: 1.57e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407 214 SPPRNLRISNVGSNSARLTWDP---TSRQINGYRIVYNNADGTEINEVEVDPI--TTFPLKGLTPLTEYTIAIFSIYDEG 288
Cdd:cd00063    2 SPPTNLRVTDVTSTSVTLSWTPpedDGGPITGYVVEYREKGSGDWKEVEVTPGseTSYTLTGLKPGTEYEFRVRAVNGGG 81

                         90
                 ....*....|..
gi 119612407 289 QSEPLTGV-FTT 299
Cdd:cd00063   82 ESPPSESVtVTT 93
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
74-459 5.83e-14

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 75.42  E-value: 5.83e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407  74 DEVVVDGTVSSTVLKNLMSLTEYQIAVFAI---YAHTASEGLRGTETTLALPMASDLLLYDVTENSMRVKWDAVP--GAS 148
Cdd:COG3401  183 TSLTVTSTTLVDGGGDIEPGTTYYYRVAATdtgGESAPSNEVSVTTPTTPPSAPTGLTATADTPGSVTLSWDPVTesDAT 262

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407 149 GYLILYAPlteglAGDEKEMKIGE-THTDIELSGLLPNTEYTVTVYAM--FGEE--ASDPVTGQETTLALSPPRNLRISN 223
Cdd:COG3401  263 GYRVYRSN-----SGDGPFTKVATvTTTSYTDTGLTNGTTYYYRVTAVdaAGNEsaPSNVVSVTTDLTPPAAPSGLTATA 337

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407 224 VGSNSARLTWDP-TSRQINGYRIVYNNADGTEINEV-EVDPITTFPLKGLTPLTEYTIAIFSIYDEG----QSEPLTGVF 297
Cdd:COG3401  338 VGSSSITLSWTAsSDADVTGYNVYRSTSGGGTYTKIaETVTTTSYTDTGLTPGTTYYYKVTAVDAAGnesaPSEEVSATT 417

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407 298 TTEEVPAQQYLEIDEVTTDSFRVTWHPLSADEGLHKLMWIPVYGGKTEEVVLKEEQDSHVIEGLEPGTEYEVSLLAVLDD 377
Cdd:COG3401  418 ASAASGESLTASVDAVPLTDVAGATAAASAASNPGVSAAVLADGGDTGNAVPFTTTSSTVTATTTDTTTANLSVTTGSLV 497

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407 378 GSESEVVTAVGTTLDSFWTEPATTIVPTTSVTSVFQTGIRNLV-VGDETTSSLRVKWDISDSDVQQFRVTYMTAQGDPEE 456
Cdd:COG3401  498 GGSGASSVTNSVSVIGASAAAAVGGAPDGTPNVTGASPVTVGAsTGDVLITDLVSLTTSASSSVSGAGLGSGNLYLITTL 577


                 ...
gi 119612407 457 EVI 459
Cdd:COG3401  578 GGS 580
fn3 pfam00041
Fibronectin type III domain;
214-292 2.00e-12

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 63.20  E-value: 2.00e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407  214 SPPRNLRISNVGSNSARLTWDP---TSRQINGYRIVYNNADGTEI-NEVEVDP-ITTFPLKGLTPLTEYTIAIFSIYDEG 288
Cdd:pfam00041   1 SAPSNLTVTDVTSTSLTVSWTPppdGNGPITGYEVEYRPKNSGEPwNEITVPGtTTSVTLTGLKPGTEYEVRVQAVNGGG 80


                  ....
gi 119612407  289 QSEP 292
Cdd:pfam00041  81 EGPP 84
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 214-290 1.23e-11

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 61.09  E-value: 1.23e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407   214 SPPRNLRISNVGSNSARLTWDPTSRQIN-----GYRIVYNNADGTEINEVEVDPITTFPLKGLTPLTEYTIAIFSIYDEG 288
Cdd:smart00060   2 SPPSNLRVTDVTSTSVTLSWEPPPDDGItgyivGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAG 81


                   ..
gi 119612407   289 QS 290
Cdd:smart00060  82 EG 83
fn3 pfam00041
Fibronectin type III domain;
510-579 1.34e-11

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 60.89  E-value: 1.34e-11
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 119612407  510 PQNLRVSEEWYNRLRITWDPP---SSPVKGYRIVYKPVSVPGPTLETFVGADINTILITNLLSGMDYNVKIFA 579
Cdd:pfam00041   3 PSNLTVTDVTSTSLTVSWTPPpdgNGPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQA 75
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 508-590 2.03e-10

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 57.89  E-value: 2.03e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407 508 SGPQNLRVSEEWYNRLRITWDPPS---SPVKGYRIVYKPVSVPGPTLETFVGADINTILITNLLSGMDYNVKIFASQASG 584
Cdd:cd00063    2 SPPTNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGG 81


                 ....*.
gi 119612407 585 FSDALT 590
Cdd:cd00063   82 ESPPSE 87
fn3 pfam00041
Fibronectin type III domain;
32-110 6.56e-10

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 56.27  E-value: 6.56e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407   32 GPPTELITSEVTARSFMVNWTHAP---GNVEKYRVVYYPTRGGKPD-EVVVDGTVSSTVLKNLMSLTEYQIAVFAIYAHT 107
Cdd:pfam00041   1 SAPSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGEPWnEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80


                  ...
gi 119612407  108 ASE 110
Cdd:pfam00041  81 EGP 83
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 32-110 1.40e-08

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 52.50  E-value: 1.40e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407  32 GPPTELITSEVTARSFMVNWTHAP---GNVEKYRVVYYPTRGGKPDEV-VVDGTVSSTVLKNLMSLTEYQIAVFAIYAHT 107
Cdd:cd00063    2 SPPTNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDWKEVeVTPGSETSYTLTGLKPGTEYEFRVRAVNGGG 81


                 ...
gi 119612407 108 ASE 110
Cdd:cd00063   82 ESP 84
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 125-194 2.05e-08

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 51.85  E-value: 2.05e-08
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 119612407   125 SDLLLYDVTENSMRVKWDAV--PGASGYLILYAPLTEGLAGDEKEMKIGETHTDIELSGLLPNTEYTVTVYA 194
Cdd:smart00060   5 SNLRVTDVTSTSVTLSWEPPpdDGITGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRA 76
fn3 pfam00041
Fibronectin type III domain;
125-194 8.09e-08

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 50.11  E-value: 8.09e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 119612407  125 SDLLLYDVTENSMRVKWDAVPGASG----YLILYAPLTEGlaGDEKEMKIGETHTDIELSGLLPNTEYTVTVYA 194
Cdd:pfam00041   4 SNLTVTDVTSTSLTVSWTPPPDGNGpitgYEVEYRPKNSG--EPWNEITVPGTTTSVTLTGLKPGTEYEVRVQA 75
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 308-379 8.38e-08

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 50.31  E-value: 8.38e-08
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 119612407   308 LEIDEVTTDSFRVTWHPLSADEGLH-KLMWIPVY---GGKTEEVVLKEEQDSHVIEGLEPGTEYEVSLLAVLDDGS 379
Cdd:smart00060   7 LRVTDVTSTSVTLSWEPPPDDGITGyIVGYRVEYreeGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAGE 82
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 308-390 2.94e-07

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 49.03  E-value: 2.94e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407 308 LEIDEVTTDSFRVTWHPLSADEGLH---KLMWIPVYGGKTEEVVLKEEQD-SHVIEGLEPGTEYEVSLLAVLDDGSESEV 383
Cdd:cd00063    7 LRVTDVTSTSVTLSWTPPEDDGGPItgyVVEYREKGSGDWKEVEVTPGSEtSYTLTGLKPGTEYEFRVRAVNGGGESPPS 86


                 ....*..
gi 119612407 384 VTAVGTT 390
Cdd:cd00063   87 ESVTVTT 93
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 508-586 5.48e-07

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 47.99  E-value: 5.48e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407   508 SGPQNLRVSEEWYNRLRITWDPPSSP-VKGYRIVYKPVSVPGPTLETFVGADI--NTILITNLLSGMDYNVKIFASQASG 584
Cdd:smart00060   2 SPPSNLRVTDVTSTSVTLSWEPPPDDgITGYIVGYRVEYREEGSEWKEVNVTPssTSYTLTGLKPGTEYEFRVRAVNGAG 81


                   ..
gi 119612407   585 FS 586
Cdd:smart00060  82 EG 83
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 125-210 6.35e-07

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 47.88  E-value: 6.35e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407 125 SDLLLYDVTENSMRVKWDAVPGA----SGYLILYAPLTEGlaGDEKEMKIGETHTDIELSGLLPNTEYTVTVYAMFGEEA 200
Cdd:cd00063    5 TNLRVTDVTSTSVTLSWTPPEDDggpiTGYVVEYREKGSG--DWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGE 82

                         90
                 ....*....|
gi 119612407 201 SDPVTGQETT 210
Cdd:cd00063   83 SPPSESVTVT 92
fn3 pfam00041
Fibronectin type III domain;
303-378 6.62e-07

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 47.79  E-value: 6.62e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407  303 PAQQYLEIDEVTTDSFRVTWHPLSADEG---LHKLMWIPVYGGKTE-EVVLKEEQDSHVIEGLEPGTEYEVSLLAVLDDG 378
Cdd:pfam00041   1 SAPSNLTVTDVTSTSLTVSWTPPPDGNGpitGYEVEYRPKNSGEPWnEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
33-298 8.41e-07

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 52.31  E-value: 8.41e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407  33 PPTELITSEVTARSFMVNWT-HAPGNVEKYRVvYYPTRGGKPDEVVVDGTVSSTVLKNLMSLTEYQIAVFAIYAH----T 107
Cdd:COG3401  235 APTGLTATADTPGSVTLSWDpVTESDATGYRV-YRSNSGDGPFTKVATVTTTSYTDTGLTNGTTYYYRVTAVDAAgnesA 313

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407 108 ASEGLRGTETTLALPMASDLLLYDVTENSMRVKWDAVPG--ASGYLILYAPLTEGLAGDEKEMKIGETHTDielSGLLPN 185
Cdd:COG3401  314 PSNVVSVTTDLTPPAAPSGLTATAVGSSSITLSWTASSDadVTGYNVYRSTSGGGTYTKIAETVTTTSYTD---TGLTPG 390

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407 186 TEYTVTVYAM----FGEEASDPVTGQETTLALSPPRNLRISNVGSN-SARLTWDPTSRQINGYRIVYNNADGTEINEVEV 260
Cdd:COG3401  391 TTYYYKVTAVdaagNESAPSEEVSATTASAASGESLTASVDAVPLTdVAGATAAASAASNPGVSAAVLADGGDTGNAVPF 470

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 119612407 261 DPITTFPLKGLTPLTEYTIAIFSIYDEGQSEPLTGVFT 298
Cdd:COG3401  471 TTTSSTVTATTTDTTTANLSVTTGSLVGGSGASSVTNS 508
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 32-109 8.42e-07

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 47.22  E-value: 8.42e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407    32 GPPTELITSEVTARSFMVNWTH-APGNVEKYRVVYYPTRGGKPD---EVVVDGTVSSTVLKNLMSLTEYQIAVFAIYAHT 107
Cdd:smart00060   2 SPPSNLRVTDVTSTSVTLSWEPpPDDGITGYIVGYRVEYREEGSewkEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAG 81


                   ..
gi 119612407   108 AS 109
Cdd:smart00060  82 EG 83
COG4733 COG4733
Phage-related protein, tail protein J [Mobilome: prophages, transposons];
102-504 3.39e-06

Phage-related protein, tail protein J [Mobilome: prophages, transposons];


Pssm-ID: 443767 [Multi-domain]  Cd Length: 978  Bit Score: 50.71  E-value: 3.39e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407 102 AIYAHTASEGL-----RGTETTLALPMASDLLLYDVTENSMRVKWDAVPGASGYLILYapltegLAGDEKEMKIGETH-T 175
Cdd:COG4733  514 EKYAAIDAGAFddvppQWPPVNVTTSESLSVVAQGTAVTTLTVSWDAPAGAVAYEVEW------RRDDGNWVSVPRTSgT 587

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407 176 DIELSGLLPNTeYTVTVYAM-FGEEASDPVTGQETTL-----ALSPPRNLRISNvGSNSARLTWD-PTSRQINGYRIVYN 248
Cdd:COG4733  588 SFEVPGIYAGD-YEVRVRAInALGVSSAWAASSETTVtgktaPPPAPTGLTATG-GLGGITLSWSfPVDADTLRTEIRYS 665

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407 249 NADGTEINEVEVD--PITTFPLKGLTPLTEYTIAIFSIYDEGQSEPLTGVFTTEEVPAQQYLEIDEVTTDSfrVTWHPLS 326
Cdd:COG4733  666 TTGDWASATVAQAlyPGNTYTLAGLKAGQTYYYRARAVDRSGNVSAWWVSGQASADAAGILDAITGQILET--ELGQELD 743

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407 327 ADE------GLHKLMWIPVYGGKTEEVVLKEEQDSHVIEGLEPGTEYEVSLLAVLDDGSESEVVTAVGTTLDSFWTEPAT 400
Cdd:COG4733  744 AIIqnatvaEVVAATVTDVTAQIDTAVLFAGVATAAAIGAEARVAATVAESATAAAATGTAADAAGDASGGVTAGTSGTT 823

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407 401 TIvPTTSVTSVFQTGIRNLVVGDETTSSLRVKWDISDSDVQQFRVTymTAQGDPEEEVIGTVMVPGSQNNLLLKPLLPDT 480
Cdd:COG4733  824 GA-GDTAASTTRVAAAVVLAGVVVYGDAIIESGNTGDIVATGDIAS--AAAGAVATTVSGTTAADVSAVADSTAASLTAI 900

                        410       420
                 ....*....|....*....|....
gi 119612407 481 EYKVTVTPIYTDGEGVSVSAPGKT 504
Cdd:COG4733  901 VIAATTIIDAIGDGTTREPAGDIG 924
fn3 pfam00041
Fibronectin type III domain;
600-675 2.71e-04

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 40.09  E-value: 2.71e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407  600 VTNLQAKHVEMTSLCAHWQ----VHRHATAYRVVIESLQD-RQKQESTVGGGTTRHCFYGLQPDSEYKISVYTKLQEIEG 674
Cdd:pfam00041   3 PSNLTVTDVTSTSLTVSWTpppdGNGPITGYEVEYRPKNSgEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGGEG 82


                  .
gi 119612407  675 P 675
Cdd:pfam00041  83 P 83
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 417-495 4.29e-04

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 39.52  E-value: 4.29e-04
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 119612407   417 RNLVVGDETTSSLRVKWDISDSDVQQFRVTYMTAQGDPEEEVIGTVMVPGSQNNLLLKPLLPDTEYKVTVTPIYTDGEG 495
Cdd:smart00060   5 SNLRVTDVTSTSVTLSWEPPPDDGITGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAGEG 83
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
117-591 4.03e-03

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 40.37  E-value: 4.03e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407 117 TTLALPMASDLLLYDVTENSMRVKWDAVPGASGYLILYAPLTEGLAGDEKEMKIGETHTDIELSGLLPNTEYTVTVYAMF 196
Cdd:COG3401   45 SVTTKESPGTLLVAAGLSSGGGLGTGGRAGTTSGVAAVAVAAAPPTATGLTTLTGSGSVGGATNTGLTSSDEVPSPAVGT 124

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407 197 GEEASDPVTGQETTLALSPPRNLriSNVGSNSARLTWDPTSRQINGYRIVYNNADGTEINEVEVDPITTFPLKGLT--PL 274
Cdd:COG3401  125 ATTATAVAGGAATAGTYALGAGL--YGVDGANASGTTASSVAGAGVVVSPDTSATAAVATTSLTVTSTTLVDGGGDiePG 202

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407 275 TEYTIAIFSIYDEGQSEP---LTGVFTTEEVPAQQYLEIDEVTTDSFRVTWHPlSADEGL--HKLMWIPVYGGKTEEVVl 349
Cdd:COG3401  203 TTYYYRVAATDTGGESAPsneVSVTTPTTPPSAPTGLTATADTPGSVTLSWDP-VTESDAtgYRVYRSNSGDGPFTKVA- 280

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407 350 KEEQDSHVIEGLEPGTEYEVSLLAVLDDGSESEVVTAVGTTLDsfwtepatTIVPTTsvtsvfqtgIRNLVVGDETTSSL 429
Cdd:COG3401  281 TVTTTSYTDTGLTNGTTYYYRVTAVDAAGNESAPSNVVSVTTD--------LTPPAA---------PSGLTATAVGSSSI 343

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407 430 RVKWD-ISDSDVQQFRVTYMTAQGDPEEEVIGTVmvpgSQNNLLLKPLLPDTEYKVTVTPIYTDGEGVSVSAP---GKTL 505
Cdd:COG3401  344 TLSWTaSSDADVTGYNVYRSTSGGGTYTKIAETV----TTTSYTDTGLTPGTTYYYKVTAVDAAGNESAPSEEvsaTTAS 419

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407 506 PSSGPQNLRVSEEWYNRLRITWDPPSSPVKGYRIVYKPVSVPGPTLETFVGADINTILITNLLSGMDYNVKIFASQASGF 585
Cdd:COG3401  420 AASGESLTASVDAVPLTDVAGATAAASAASNPGVSAAVLADGGDTGNAVPFTTTSSTVTATTTDTTTANLSVTTGSLVGG 499


                 ....*.
gi 119612407 586 SDALTG 591
Cdd:COG3401  500 SGASSV 505
fn3 pfam00041
Fibronectin type III domain;
417-495 9.48e-03

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 35.85  E-value: 9.48e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119612407  417 RNLVVGDETTSSLRVKWDIS---DSDVQQFRVTYmTAQGDPEEEVigTVMVPGSQNNLLLKPLLPDTEYKVTVTPIYTDG 493
Cdd:pfam00041   4 SNLTVTDVTSTSLTVSWTPPpdgNGPITGYEVEY-RPKNSGEPWN--EITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80


                  ..
gi 119612407  494 EG 495
Cdd:pfam00041  81 EG 82
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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