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Conserved domains on  [gi|261358019|gb|EEY20447|]
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conserved hypothetical protein [Verticillium alfalfae VaMs.102]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF3140 pfam11338
Protein of unknown function (DUF3140); Some members in this family of proteins are annotated ...
 1-99 1.96e-31

Protein of unknown function (DUF3140); Some members in this family of proteins are annotated as DNA binding proteins. No function is currently known.


:

Pssm-ID: 431824  Cd Length: 92  Bit Score: 113.49  E-value: 1.96e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261358019    1 MTASDLETWLKSDDANSAGWPKDDadgdGETVGHDSGRKIVEILKanpdRKEDKYTDEQVEHMRKVVAYCKRHLAQeakg 80
Cdd:pfam11338   8 MTSKELEDWLETDESGSVGWTKDG----GESVGHESGRRIVEILR----KRKADLTDDDVEHMRKVVGYVKRHLAQ---- 75

                          90
                  ....*....|....*....
gi 261358019   81 neEKTDEEVKKTKSYASLK 99
Cdd:pfam11338  76 --EEPSGDVEDTRWRYSLM 92
Hva1_TUDOR pfam11160
Hypervirulence associated proteins TUDOR domain; Family members include HVA1 ...
 282-341 4.14e-11

Hypervirulence associated proteins TUDOR domain; Family members include HVA1 (hypervirulence-associated protein 1) whose absence is associated with a hypervirulent phenotype in mice. Metabolomics analysis suggests that when HVA1 is absent there is a block in the citric acid cycle, while structural analysis of the Hva1 protein suggests a potential interaction with NADPH. The structural architecture of Hva1 bears similarity with Tudor domains.


:

Pssm-ID: 431691 [Multi-domain]  Cd Length: 59  Bit Score: 57.51  E-value: 4.14e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 261358019  282 TVSWNWGGGQPEGKVLDVKgedTSITTKNGnqVTRKGDPEDPAVVIDAGKS--KAIKSAHEL 341
Cdd:pfam11160   3 KVSWKWGGGTAEGKVVEVL---TEETEAKG--VTVNASEDDPAYEIESDKTgkDVVHKPSEL 59
 
Name Accession Description Interval E-value
DUF3140 pfam11338
Protein of unknown function (DUF3140); Some members in this family of proteins are annotated ...
 1-99 1.96e-31

Protein of unknown function (DUF3140); Some members in this family of proteins are annotated as DNA binding proteins. No function is currently known.


Pssm-ID: 431824  Cd Length: 92  Bit Score: 113.49  E-value: 1.96e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261358019    1 MTASDLETWLKSDDANSAGWPKDDadgdGETVGHDSGRKIVEILKanpdRKEDKYTDEQVEHMRKVVAYCKRHLAQeakg 80
Cdd:pfam11338   8 MTSKELEDWLETDESGSVGWTKDG----GESVGHESGRRIVEILR----KRKADLTDDDVEHMRKVVGYVKRHLAQ---- 75

                          90
                  ....*....|....*....
gi 261358019   81 neEKTDEEVKKTKSYASLK 99
Cdd:pfam11338  76 --EEPSGDVEDTRWRYSLM 92
Hva1_TUDOR pfam11160
Hypervirulence associated proteins TUDOR domain; Family members include HVA1 ...
 282-341 4.14e-11

Hypervirulence associated proteins TUDOR domain; Family members include HVA1 (hypervirulence-associated protein 1) whose absence is associated with a hypervirulent phenotype in mice. Metabolomics analysis suggests that when HVA1 is absent there is a block in the citric acid cycle, while structural analysis of the Hva1 protein suggests a potential interaction with NADPH. The structural architecture of Hva1 bears similarity with Tudor domains.


Pssm-ID: 431691 [Multi-domain]  Cd Length: 59  Bit Score: 57.51  E-value: 4.14e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 261358019  282 TVSWNWGGGQPEGKVLDVKgedTSITTKNGnqVTRKGDPEDPAVVIDAGKS--KAIKSAHEL 341
Cdd:pfam11160   3 KVSWKWGGGTAEGKVVEVL---TEETEAKG--VTVNASEDDPAYEIESDKTgkDVVHKPSEL 59
 
Name Accession Description Interval E-value
DUF3140 pfam11338
Protein of unknown function (DUF3140); Some members in this family of proteins are annotated ...
 1-99 1.96e-31

Protein of unknown function (DUF3140); Some members in this family of proteins are annotated as DNA binding proteins. No function is currently known.


Pssm-ID: 431824  Cd Length: 92  Bit Score: 113.49  E-value: 1.96e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261358019    1 MTASDLETWLKSDDANSAGWPKDDadgdGETVGHDSGRKIVEILKanpdRKEDKYTDEQVEHMRKVVAYCKRHLAQeakg 80
Cdd:pfam11338   8 MTSKELEDWLETDESGSVGWTKDG----GESVGHESGRRIVEILR----KRKADLTDDDVEHMRKVVGYVKRHLAQ---- 75

                          90
                  ....*....|....*....
gi 261358019   81 neEKTDEEVKKTKSYASLK 99
Cdd:pfam11338  76 --EEPSGDVEDTRWRYSLM 92
Hva1_TUDOR pfam11160
Hypervirulence associated proteins TUDOR domain; Family members include HVA1 ...
 282-341 4.14e-11

Hypervirulence associated proteins TUDOR domain; Family members include HVA1 (hypervirulence-associated protein 1) whose absence is associated with a hypervirulent phenotype in mice. Metabolomics analysis suggests that when HVA1 is absent there is a block in the citric acid cycle, while structural analysis of the Hva1 protein suggests a potential interaction with NADPH. The structural architecture of Hva1 bears similarity with Tudor domains.


Pssm-ID: 431691 [Multi-domain]  Cd Length: 59  Bit Score: 57.51  E-value: 4.14e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 261358019  282 TVSWNWGGGQPEGKVLDVKgedTSITTKNGnqVTRKGDPEDPAVVIDAGKS--KAIKSAHEL 341
Cdd:pfam11160   3 KVSWKWGGGTAEGKVVEVL---TEETEAKG--VTVNASEDDPAYEIESDKTgkDVVHKPSEL 59
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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