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Conserved domains on  [gi|577146273|gb|EUD69562|]
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hypothetical protein C922_00426 [Plasmodium inui San Antonio 1]

Protein Classification

ETRAMP family protein( domain architecture ID 10560652)

ETRAMP (early transcribed membrane protein) family protein is a small transmembrane molecule, similar to Plasmodium ETRAMP usually expressed in a stage-specific manner that localizes to the parasitophorous vacuole membrane and to vesicle-like structures exported to the host erythrocyte cytosol

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ETRAMP pfam09716
Malarial early transcribed membrane protein (ETRAMP); These sequences represent a family of ...
 1-78 4.63e-12

Malarial early transcribed membrane protein (ETRAMP); These sequences represent a family of proteins from the malaria parasite Plasmodium falciparum, several of which have been shown to be expressed specifically in the ring stage as well as the rodent parasite Plasmodium yoelii. A homolog from Plasmodium chabaudi was localized to the parasitophorous vacuole membrane. Members have an initial hydrophobic, Phe/Tyr-rich, stretch long enough to span the membrane, a highly charged region rich in Lys, a second putative transmembrane region and a second highly charged, low complexity sequence region. Some members have up to 100 residues of additional C-terminal sequence. These genes have been shown to be found in the sub-telomeric regions of both Plasmodium falciparum and P. yoelii chromosomes.


:

Pssm-ID: 430768  Cd Length: 81  Bit Score: 58.78  E-value: 4.63e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577146273    1 MNITKVYIFILILLFNILFEPHLCNAVV-KRSDSHLMKLTIDELNKK--RKKKVIYAVIGVVLGILALAAGGLGMTYRRK 77
Cdd:pfam09716   1 MKLTKVLYFFAFLLAINLLTPCLCNNVVaKEKNKKALKKIDDKLEKKkkKKKIIIISSIASGLALLVATALGVGYYMKKK 80


                  .
gi 577146273   78 K 78
Cdd:pfam09716  81 K 81
 
Name Accession Description Interval E-value
ETRAMP pfam09716
Malarial early transcribed membrane protein (ETRAMP); These sequences represent a family of ...
 1-78 4.63e-12

Malarial early transcribed membrane protein (ETRAMP); These sequences represent a family of proteins from the malaria parasite Plasmodium falciparum, several of which have been shown to be expressed specifically in the ring stage as well as the rodent parasite Plasmodium yoelii. A homolog from Plasmodium chabaudi was localized to the parasitophorous vacuole membrane. Members have an initial hydrophobic, Phe/Tyr-rich, stretch long enough to span the membrane, a highly charged region rich in Lys, a second putative transmembrane region and a second highly charged, low complexity sequence region. Some members have up to 100 residues of additional C-terminal sequence. These genes have been shown to be found in the sub-telomeric regions of both Plasmodium falciparum and P. yoelii chromosomes.


Pssm-ID: 430768  Cd Length: 81  Bit Score: 58.78  E-value: 4.63e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577146273    1 MNITKVYIFILILLFNILFEPHLCNAVV-KRSDSHLMKLTIDELNKK--RKKKVIYAVIGVVLGILALAAGGLGMTYRRK 77
Cdd:pfam09716   1 MKLTKVLYFFAFLLAINLLTPCLCNNVVaKEKNKKALKKIDDKLEKKkkKKKIIIISSIASGLALLVATALGVGYYMKKK 80


                  .
gi 577146273   78 K 78
Cdd:pfam09716  81 K 81
ETRAMP TIGR01495
Plasmodium ring stage membrane protein ETRAMP; This model describes a family of proteins from ...
 1-78 2.26e-07

Plasmodium ring stage membrane protein ETRAMP; This model describes a family of proteins from the malaria parasite Plasmodium falciparum, several of which have been shown to be expressed specifically in the ring stage as well as the rident parasite Plasmodium yoelii. A homolog from Plasmodium chabaudi was localized to the parasitophorous vacuole membrane. Members have an initial hydrophobic, Phe/Tyr-rich stretch long enough to span the membrane, a highly charged region rich in Lys, a second putative transmembrane region, and a second highly charged, low complexity sequence region. Some members have up to 100 residues of additional C-terminal sequence. These genes have been shown to be found in the sub-telomeric regions of both P. falciparum and P. yoelii chromosomes


Pssm-ID: 130559  Cd Length: 85  Bit Score: 46.56  E-value: 2.26e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 577146273    1 MNITKVYIFILILLFNILFEPHLC-NAVVKRSDSHLMKLTIDELNKKRKKKVIYAVIGVVLGILALAAGGLGMTYRRKK 78
Cdd:TIGR01495   1 MKVSKILYFFAALLAINFIAPGYCnNGKKVNKKGNLKKLTKAEKKKKNKKIILYSSIASGLALLVGAGVGLGYYYKKKN 79
 
Name Accession Description Interval E-value
ETRAMP pfam09716
Malarial early transcribed membrane protein (ETRAMP); These sequences represent a family of ...
 1-78 4.63e-12

Malarial early transcribed membrane protein (ETRAMP); These sequences represent a family of proteins from the malaria parasite Plasmodium falciparum, several of which have been shown to be expressed specifically in the ring stage as well as the rodent parasite Plasmodium yoelii. A homolog from Plasmodium chabaudi was localized to the parasitophorous vacuole membrane. Members have an initial hydrophobic, Phe/Tyr-rich, stretch long enough to span the membrane, a highly charged region rich in Lys, a second putative transmembrane region and a second highly charged, low complexity sequence region. Some members have up to 100 residues of additional C-terminal sequence. These genes have been shown to be found in the sub-telomeric regions of both Plasmodium falciparum and P. yoelii chromosomes.


Pssm-ID: 430768  Cd Length: 81  Bit Score: 58.78  E-value: 4.63e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577146273    1 MNITKVYIFILILLFNILFEPHLCNAVV-KRSDSHLMKLTIDELNKK--RKKKVIYAVIGVVLGILALAAGGLGMTYRRK 77
Cdd:pfam09716   1 MKLTKVLYFFAFLLAINLLTPCLCNNVVaKEKNKKALKKIDDKLEKKkkKKKIIIISSIASGLALLVATALGVGYYMKKK 80


                  .
gi 577146273   78 K 78
Cdd:pfam09716  81 K 81
ETRAMP TIGR01495
Plasmodium ring stage membrane protein ETRAMP; This model describes a family of proteins from ...
 1-78 2.26e-07

Plasmodium ring stage membrane protein ETRAMP; This model describes a family of proteins from the malaria parasite Plasmodium falciparum, several of which have been shown to be expressed specifically in the ring stage as well as the rident parasite Plasmodium yoelii. A homolog from Plasmodium chabaudi was localized to the parasitophorous vacuole membrane. Members have an initial hydrophobic, Phe/Tyr-rich stretch long enough to span the membrane, a highly charged region rich in Lys, a second putative transmembrane region, and a second highly charged, low complexity sequence region. Some members have up to 100 residues of additional C-terminal sequence. These genes have been shown to be found in the sub-telomeric regions of both P. falciparum and P. yoelii chromosomes


Pssm-ID: 130559  Cd Length: 85  Bit Score: 46.56  E-value: 2.26e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 577146273    1 MNITKVYIFILILLFNILFEPHLC-NAVVKRSDSHLMKLTIDELNKKRKKKVIYAVIGVVLGILALAAGGLGMTYRRKK 78
Cdd:TIGR01495   1 MKVSKILYFFAALLAINFIAPGYCnNGKKVNKKGNLKKLTKAEKKKKNKKIILYSSIASGLALLVGAGVGLGYYYKKKN 79
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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