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Conserved domains on  [gi|1902075388|dbj|GGM85470|]
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hypothetical protein GCM10009721_07750 [Terrabacter tumescens]

Protein Classification

MalT transcriptional regulator family protein( domain architecture ID 1001203)

MalT transcriptional regulator family protein similar to HTH-type transcriptional regulator MalT that positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides

Gene Ontology:  GO:0003700|GO:0003677|GO:0045893|GO:0005524
PubMed:  8809174|3015733

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK04841 super family cl35271
HTH-type transcriptional regulator MalT;
4-901 1.55e-86

HTH-type transcriptional regulator MalT;


The actual alignment was detected with superfamily member PRK04841:

Pssm-ID: 235315 [Multi-domain]  Cd Length: 903  Bit Score: 296.09  E-value: 1.55e-86
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388   4 PLVRTKLYVPRARHTVVPRARLLDRLVDrlgtGGQPRLTVVSAPAGFGKTTLLAAWAAAAPRPVAwVSLEASEQHPGTFW 83
Cdd:PRK04841    1 MLIPSKLSRPVRLHNTVVRERLLAKLSG----ANNYRLVLVTSPAGYGKTTLISQWAAGKNNLGW-YSLDESDNQPERFA 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388  84 TYVVTALDTAVPGVgagvLPLLQATA-----PHPGAVVATLLNALEAVTGGVDLVLDDYHLADAPAIADDVAYLVEHLPT 158
Cdd:PRK04841   76 SYLIAALQQATNGH----CSKSEALAqkrqyASLSSLFAQLFIELADWHQPLYLVIDDYHLITNPEIHEAMRFFLRHQPE 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 159 DVHVLLGTRADPDLPLARLRARGELVEVRAADLRFTLAEVTAYLNDVAGLDLDAREIAVLEDRTEGWVAA----LQLAAL 234
Cdd:PRK04841  152 NLTLVVLSRNLPPLGIANLRVRDQLLEIGSQQLAFDHQEAQQFFDQRLSSPIEAAESSRLCDDVEGWATAlqliALSARQ 231

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 235 SLRGREDPAGFIAGFAgdDRYVVDYLVEEVVRRQPEHVRRFLLETSVLDRLGGPLCDAVTGAGDSRSVLEFLERANLFVI 314
Cdd:PRK04841  232 NNSSLHDSARRLAGIN--ASHLSDYLVEEVLDNVDLETRHFLLRCSVLRSMNDALIVRVTGEENGQMRLEELERQGLFIQ 309

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 315 PLDDSRQWYRYHHLFADVLRAHLAQERPLEVAGLHRRAAEWYAADGEPEPAVRHALAAGDVELAADLVERSAIELLRRRQ 394
Cdd:PRK04841  310 RMDDSGEWFRYHPLFASFLRHRCQWELAQELPELHRAAAEAWLAQGFPSEAIHHALAAGDAQLLRDILLQHGWSLFNQGE 389

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 395 EATVRGWIDAIPDAVVRVRPVLAIafIGALMSRGEFdtvpdRLAHLEGLLADPAAEVVVLDEREAARVPGAMETYRAALA 474
Cdd:PRK04841  390 LSLLEECLNALPWEVLLENPRLVL--LQAWLAQSQH-----RYSEVNTLLARAEQELKDRNIELDGTLQAEFNALRAQVA 462

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 475 LVAGDPAGTVEHADLAIEraapgddltvaaasalaglaswaagDLESAHRaYSGAVegleragnisdvlGCSItLGDLRI 554
Cdd:PRK04841  463 INDGDPEEAERLAELALA-------------------------ELPLTWY-YSRIV-------------ATSV-LGEVHH 502

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 555 TQGRLDDARRTYERALRLAAAHEAdgaggtggplrgvadMEVGL------SEIALEQGHLTEAAAHLGRVAALGERLGLP 628
Cdd:PRK04841  503 CKGELARALAMMQQTEQMARQHDV---------------YHYALwsllqqSEILFAQGFLQAAYETQEKAFQLIEEQHLE 567

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 629 QLP-----YRRRV----AEARLREAE--------------------------------GDLAGAVALLEEAEKVY-VGDY 666
Cdd:PRK04841  568 QLPmheflLRIRAqllwEWARLDEAEqcarkglevlsnyqpqqqlqclamlakislarGDLDNARRYLNRLENLLgNGRY 647

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 667 SPDVRPLpAQRARVLV--AQGRVDEARQWARTrGLAPDDELSYVREYEHVTLARVLMH-GRdtsgatTRTAYDLLERLRV 743
Cdd:PRK04841  648 HSDWIAN-ADKVRLIYwqMTGDKEAAANWLRQ-APKPEFANNHFLQGQWRNIARAQILlGQ------FDEAEIILEELNE 719

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 744 AAEEDGRTGSLIEILSLQA-LATLAGSEtpdvSAALAPLERALRLAEPTGHVRVFVGEGAPVAVLLAAVVERN--PSWAY 820
Cdd:PRK04841  720 NARSLRLMSDLNRNLILLNqLYWQQGRK----SEAQRVLLEALKLANRTGFISHFVIEGEAMAQQLRQLIQLNtlPELEQ 795

                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 821 PR--RLLDALRPESSGASGH---GLVD---------------PLSSRELEVLRLLATSLDGPEIARRLFISLNTLRTHTK 880
Cdd:PRK04841  796 HRaqRILREINQHHRHKFAHfdeAFVEkllnhpdvpelirtsPLTQREWQVLGLIYSGYSNEQIAGELDVAATTIKTHIR 875

                         970       980
                  ....*....|....*....|.
gi 1902075388 881 NVYAKLGVNRRRDAVTRAGEL 901
Cdd:PRK04841  876 NLYQKLGIAHRQEAVQHAQDL 896
 
Name Accession Description Interval E-value
PRK04841 PRK04841
HTH-type transcriptional regulator MalT;
4-901 1.55e-86

HTH-type transcriptional regulator MalT;


Pssm-ID: 235315 [Multi-domain]  Cd Length: 903  Bit Score: 296.09  E-value: 1.55e-86
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388   4 PLVRTKLYVPRARHTVVPRARLLDRLVDrlgtGGQPRLTVVSAPAGFGKTTLLAAWAAAAPRPVAwVSLEASEQHPGTFW 83
Cdd:PRK04841    1 MLIPSKLSRPVRLHNTVVRERLLAKLSG----ANNYRLVLVTSPAGYGKTTLISQWAAGKNNLGW-YSLDESDNQPERFA 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388  84 TYVVTALDTAVPGVgagvLPLLQATA-----PHPGAVVATLLNALEAVTGGVDLVLDDYHLADAPAIADDVAYLVEHLPT 158
Cdd:PRK04841   76 SYLIAALQQATNGH----CSKSEALAqkrqyASLSSLFAQLFIELADWHQPLYLVIDDYHLITNPEIHEAMRFFLRHQPE 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 159 DVHVLLGTRADPDLPLARLRARGELVEVRAADLRFTLAEVTAYLNDVAGLDLDAREIAVLEDRTEGWVAA----LQLAAL 234
Cdd:PRK04841  152 NLTLVVLSRNLPPLGIANLRVRDQLLEIGSQQLAFDHQEAQQFFDQRLSSPIEAAESSRLCDDVEGWATAlqliALSARQ 231

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 235 SLRGREDPAGFIAGFAgdDRYVVDYLVEEVVRRQPEHVRRFLLETSVLDRLGGPLCDAVTGAGDSRSVLEFLERANLFVI 314
Cdd:PRK04841  232 NNSSLHDSARRLAGIN--ASHLSDYLVEEVLDNVDLETRHFLLRCSVLRSMNDALIVRVTGEENGQMRLEELERQGLFIQ 309

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 315 PLDDSRQWYRYHHLFADVLRAHLAQERPLEVAGLHRRAAEWYAADGEPEPAVRHALAAGDVELAADLVERSAIELLRRRQ 394
Cdd:PRK04841  310 RMDDSGEWFRYHPLFASFLRHRCQWELAQELPELHRAAAEAWLAQGFPSEAIHHALAAGDAQLLRDILLQHGWSLFNQGE 389

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 395 EATVRGWIDAIPDAVVRVRPVLAIafIGALMSRGEFdtvpdRLAHLEGLLADPAAEVVVLDEREAARVPGAMETYRAALA 474
Cdd:PRK04841  390 LSLLEECLNALPWEVLLENPRLVL--LQAWLAQSQH-----RYSEVNTLLARAEQELKDRNIELDGTLQAEFNALRAQVA 462

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 475 LVAGDPAGTVEHADLAIEraapgddltvaaasalaglaswaagDLESAHRaYSGAVegleragnisdvlGCSItLGDLRI 554
Cdd:PRK04841  463 INDGDPEEAERLAELALA-------------------------ELPLTWY-YSRIV-------------ATSV-LGEVHH 502

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 555 TQGRLDDARRTYERALRLAAAHEAdgaggtggplrgvadMEVGL------SEIALEQGHLTEAAAHLGRVAALGERLGLP 628
Cdd:PRK04841  503 CKGELARALAMMQQTEQMARQHDV---------------YHYALwsllqqSEILFAQGFLQAAYETQEKAFQLIEEQHLE 567

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 629 QLP-----YRRRV----AEARLREAE--------------------------------GDLAGAVALLEEAEKVY-VGDY 666
Cdd:PRK04841  568 QLPmheflLRIRAqllwEWARLDEAEqcarkglevlsnyqpqqqlqclamlakislarGDLDNARRYLNRLENLLgNGRY 647

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 667 SPDVRPLpAQRARVLV--AQGRVDEARQWARTrGLAPDDELSYVREYEHVTLARVLMH-GRdtsgatTRTAYDLLERLRV 743
Cdd:PRK04841  648 HSDWIAN-ADKVRLIYwqMTGDKEAAANWLRQ-APKPEFANNHFLQGQWRNIARAQILlGQ------FDEAEIILEELNE 719

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 744 AAEEDGRTGSLIEILSLQA-LATLAGSEtpdvSAALAPLERALRLAEPTGHVRVFVGEGAPVAVLLAAVVERN--PSWAY 820
Cdd:PRK04841  720 NARSLRLMSDLNRNLILLNqLYWQQGRK----SEAQRVLLEALKLANRTGFISHFVIEGEAMAQQLRQLIQLNtlPELEQ 795

                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 821 PR--RLLDALRPESSGASGH---GLVD---------------PLSSRELEVLRLLATSLDGPEIARRLFISLNTLRTHTK 880
Cdd:PRK04841  796 HRaqRILREINQHHRHKFAHfdeAFVEkllnhpdvpelirtsPLTQREWQVLGLIYSGYSNEQIAGELDVAATTIKTHIR 875

                         970       980
                  ....*....|....*....|.
gi 1902075388 881 NVYAKLGVNRRRDAVTRAGEL 901
Cdd:PRK04841  876 NLYQKLGIAHRQEAVQHAQDL 896
TPR_MalT pfam17874
MalT-like TPR region; This entry contains a series of TPR repeats.
 464-814 2.19e-45

MalT-like TPR region; This entry contains a series of TPR repeats.


Pssm-ID: 436107 [Multi-domain]  Cd Length: 336  Bit Score: 166.72  E-value: 2.19e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 464 GAMETYRAALALVAGDPAGTVEHADLAIERAAPGDDLTVAAASALAGLASWAAGDLESAHRAYSGAVEGLERAGNISDVL 543
Cdd:pfam17874   1 GEIAALRAQLAISKGDAERALELAEQALALLPEDDLLARGLATFVLGEAYLCLGDLDAALQAMREAEALARRADSPHVTL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 544 GCSITLGDLRITQGRLDDARRTYERALRLaaAHEADGAggtggPLRGVADMEVGLSEIALEQGHLTEAAAHLGRVAALGE 623
Cdd:pfam17874  81 WALLQQGEILRAQGRLHQALETYQQALQL--ARDHGLQ-----HLPLHGFLLVGLADLLYEWNDLEEAEQHAQQGIQLGR 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 624 RLGlPQLPYRRRVAEARLREAEGDLAGAVALLEEAEKVYVGDYSPDVRPLPAQRARVLV--AQGRVDEARQWARTRGLaP 701
Cdd:pfam17874 154 QWE-PDAAVDAYVLLARIALAQGELEEALTLLRRAELLARQSFFHVDWLANAERVRVRLwlARGDLRAAVRWLRAAEP-P 231

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 702 DDELSYVREYEHVTLARVLMHGRDTSGATTrtaydLLERLRVAAEEDGRTGSLIEILSLQALATLAGSETPDvsaALAPL 781
Cdd:pfam17874 232 SDADNHFLERELRNLARVLLALGRFDDALS-----LLERLQNLAEQLGRVRSLIENLILQALALLALGRPDE---ALQAL 303

                         330       340       350
                  ....*....|....*....|....*....|...
gi 1902075388 782 ERALRLAEPTGHVRVFVGEGAPVAVLLAAVVER 814
Cdd:pfam17874 304 LDALSLAEPEGYVRSFVDEGAPLARLLKRLLKR 336
GerE COG5905
Spore transcriptional regulator GerE (stand-alone HTH domain) [Cell cycle control, cell ...
 841-904 2.29e-17

Spore transcriptional regulator GerE (stand-alone HTH domain) [Cell cycle control, cell division, chromosome partitioning, Transcription];


Pssm-ID: 444607 [Multi-domain]  Cd Length: 76  Bit Score: 77.31  E-value: 2.29e-17
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1902075388 841 VDPLSSRELEVLRLLATSLDGPEIARRLFISLNTLRTHTKNVYAKLGVNRRRDAVTRAGELGLL 904
Cdd:COG5905    10 PSLLTKREREVLELLAEGLTNKEIARQLFISEKTVKNHVSNILRKLGVRNRVQAVVWALRLGLL 73
HTH_LUXR smart00421
helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon
 842-898 5.37e-15

helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon


Pssm-ID: 197715 [Multi-domain]  Cd Length: 58  Bit Score: 69.86  E-value: 5.37e-15
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1902075388  842 DPLSSRELEVLRLLATSLDGPEIARRLFISLNTLRTHTKNVYAKLGVNRRRDAVTRA 898
Cdd:smart00421   2 ASLTPREREVLRLLAEGLTNKEIAERLGISEKTVKTHLSNIMRKLGVRSRTQAVRLA 58
LuxR_C_like cd06170
C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix ...
 844-898 5.27e-13

C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many are active as homodimers. Many are two domain proteins in which the DNA binding property of the C-terminal DNA binding domain is modulated by modifications of the N-terminal domain. For example in the case of Lux R which participates in the regulation of gene expression in response to fluctuations in cell-population density (quorum-sensing), a signaling molecule, the pheromone Acyl HSL (N-acyl derivatives of homoserine lactone), binds to the N-terminal domain and leads to LuxR dimerization. For others phophorylation of the N-terminal domain leads to multimerization, for example Escherichia coli NarL and Sinorhizobium melilot FixJ. NarL controls gene expression of many respiratory-related operons when environmental nitrate or nitrite is present under anerobic conditions. FixJ is involved in the transcriptional activation of nitrogen fixation genes. The group also includes small proteins which lack an N-terminal signaling domain, such as Bacillus subtilis GerE. GerE is dimeric and acts in conjunction with sigmaK as an activator or a repressor modulating the expression of various genes in particular those encoding the spore-coat. These LuxR family regulators may share a similar organization of their target binding sites. For example the LuxR dimer binds the lux box, a 20bp inverted repeat, GerE dimers bind two 12bp consensus sequences in inverted orientation having the central four bases overlap, and the NarL dimer binds two 7bp inverted repeats separated by 2 bp.


Pssm-ID: 99777 [Multi-domain]  Cd Length: 57  Bit Score: 64.09  E-value: 5.27e-13
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1902075388 844 LSSRELEVLRLLATSLDGPEIARRLFISLNTLRTHTKNVYAKLGVNRRRDAVTRA 898
Cdd:cd06170     1 LTPREREVLRLLAEGKTNKEIADILGISEKTVKTHLRNIMRKLGVKSRTQLVAYA 55
 
Name Accession Description Interval E-value
PRK04841 PRK04841
HTH-type transcriptional regulator MalT;
4-901 1.55e-86

HTH-type transcriptional regulator MalT;


Pssm-ID: 235315 [Multi-domain]  Cd Length: 903  Bit Score: 296.09  E-value: 1.55e-86
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388   4 PLVRTKLYVPRARHTVVPRARLLDRLVDrlgtGGQPRLTVVSAPAGFGKTTLLAAWAAAAPRPVAwVSLEASEQHPGTFW 83
Cdd:PRK04841    1 MLIPSKLSRPVRLHNTVVRERLLAKLSG----ANNYRLVLVTSPAGYGKTTLISQWAAGKNNLGW-YSLDESDNQPERFA 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388  84 TYVVTALDTAVPGVgagvLPLLQATA-----PHPGAVVATLLNALEAVTGGVDLVLDDYHLADAPAIADDVAYLVEHLPT 158
Cdd:PRK04841   76 SYLIAALQQATNGH----CSKSEALAqkrqyASLSSLFAQLFIELADWHQPLYLVIDDYHLITNPEIHEAMRFFLRHQPE 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 159 DVHVLLGTRADPDLPLARLRARGELVEVRAADLRFTLAEVTAYLNDVAGLDLDAREIAVLEDRTEGWVAA----LQLAAL 234
Cdd:PRK04841  152 NLTLVVLSRNLPPLGIANLRVRDQLLEIGSQQLAFDHQEAQQFFDQRLSSPIEAAESSRLCDDVEGWATAlqliALSARQ 231

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 235 SLRGREDPAGFIAGFAgdDRYVVDYLVEEVVRRQPEHVRRFLLETSVLDRLGGPLCDAVTGAGDSRSVLEFLERANLFVI 314
Cdd:PRK04841  232 NNSSLHDSARRLAGIN--ASHLSDYLVEEVLDNVDLETRHFLLRCSVLRSMNDALIVRVTGEENGQMRLEELERQGLFIQ 309

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 315 PLDDSRQWYRYHHLFADVLRAHLAQERPLEVAGLHRRAAEWYAADGEPEPAVRHALAAGDVELAADLVERSAIELLRRRQ 394
Cdd:PRK04841  310 RMDDSGEWFRYHPLFASFLRHRCQWELAQELPELHRAAAEAWLAQGFPSEAIHHALAAGDAQLLRDILLQHGWSLFNQGE 389

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 395 EATVRGWIDAIPDAVVRVRPVLAIafIGALMSRGEFdtvpdRLAHLEGLLADPAAEVVVLDEREAARVPGAMETYRAALA 474
Cdd:PRK04841  390 LSLLEECLNALPWEVLLENPRLVL--LQAWLAQSQH-----RYSEVNTLLARAEQELKDRNIELDGTLQAEFNALRAQVA 462

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 475 LVAGDPAGTVEHADLAIEraapgddltvaaasalaglaswaagDLESAHRaYSGAVegleragnisdvlGCSItLGDLRI 554
Cdd:PRK04841  463 INDGDPEEAERLAELALA-------------------------ELPLTWY-YSRIV-------------ATSV-LGEVHH 502

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 555 TQGRLDDARRTYERALRLAAAHEAdgaggtggplrgvadMEVGL------SEIALEQGHLTEAAAHLGRVAALGERLGLP 628
Cdd:PRK04841  503 CKGELARALAMMQQTEQMARQHDV---------------YHYALwsllqqSEILFAQGFLQAAYETQEKAFQLIEEQHLE 567

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 629 QLP-----YRRRV----AEARLREAE--------------------------------GDLAGAVALLEEAEKVY-VGDY 666
Cdd:PRK04841  568 QLPmheflLRIRAqllwEWARLDEAEqcarkglevlsnyqpqqqlqclamlakislarGDLDNARRYLNRLENLLgNGRY 647

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 667 SPDVRPLpAQRARVLV--AQGRVDEARQWARTrGLAPDDELSYVREYEHVTLARVLMH-GRdtsgatTRTAYDLLERLRV 743
Cdd:PRK04841  648 HSDWIAN-ADKVRLIYwqMTGDKEAAANWLRQ-APKPEFANNHFLQGQWRNIARAQILlGQ------FDEAEIILEELNE 719

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 744 AAEEDGRTGSLIEILSLQA-LATLAGSEtpdvSAALAPLERALRLAEPTGHVRVFVGEGAPVAVLLAAVVERN--PSWAY 820
Cdd:PRK04841  720 NARSLRLMSDLNRNLILLNqLYWQQGRK----SEAQRVLLEALKLANRTGFISHFVIEGEAMAQQLRQLIQLNtlPELEQ 795

                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 821 PR--RLLDALRPESSGASGH---GLVD---------------PLSSRELEVLRLLATSLDGPEIARRLFISLNTLRTHTK 880
Cdd:PRK04841  796 HRaqRILREINQHHRHKFAHfdeAFVEkllnhpdvpelirtsPLTQREWQVLGLIYSGYSNEQIAGELDVAATTIKTHIR 875

                         970       980
                  ....*....|....*....|.
gi 1902075388 881 NVYAKLGVNRRRDAVTRAGEL 901
Cdd:PRK04841  876 NLYQKLGIAHRQEAVQHAQDL 896
TPR_MalT pfam17874
MalT-like TPR region; This entry contains a series of TPR repeats.
 464-814 2.19e-45

MalT-like TPR region; This entry contains a series of TPR repeats.


Pssm-ID: 436107 [Multi-domain]  Cd Length: 336  Bit Score: 166.72  E-value: 2.19e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 464 GAMETYRAALALVAGDPAGTVEHADLAIERAAPGDDLTVAAASALAGLASWAAGDLESAHRAYSGAVEGLERAGNISDVL 543
Cdd:pfam17874   1 GEIAALRAQLAISKGDAERALELAEQALALLPEDDLLARGLATFVLGEAYLCLGDLDAALQAMREAEALARRADSPHVTL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 544 GCSITLGDLRITQGRLDDARRTYERALRLaaAHEADGAggtggPLRGVADMEVGLSEIALEQGHLTEAAAHLGRVAALGE 623
Cdd:pfam17874  81 WALLQQGEILRAQGRLHQALETYQQALQL--ARDHGLQ-----HLPLHGFLLVGLADLLYEWNDLEEAEQHAQQGIQLGR 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 624 RLGlPQLPYRRRVAEARLREAEGDLAGAVALLEEAEKVYVGDYSPDVRPLPAQRARVLV--AQGRVDEARQWARTRGLaP 701
Cdd:pfam17874 154 QWE-PDAAVDAYVLLARIALAQGELEEALTLLRRAELLARQSFFHVDWLANAERVRVRLwlARGDLRAAVRWLRAAEP-P 231

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 702 DDELSYVREYEHVTLARVLMHGRDTSGATTrtaydLLERLRVAAEEDGRTGSLIEILSLQALATLAGSETPDvsaALAPL 781
Cdd:pfam17874 232 SDADNHFLERELRNLARVLLALGRFDDALS-----LLERLQNLAEQLGRVRSLIENLILQALALLALGRPDE---ALQAL 303

                         330       340       350
                  ....*....|....*....|....*....|...
gi 1902075388 782 ERALRLAEPTGHVRVFVGEGAPVAVLLAAVVER 814
Cdd:pfam17874 304 LDALSLAEPEGYVRSFVDEGAPLARLLKRLLKR 336
GerE COG5905
Spore transcriptional regulator GerE (stand-alone HTH domain) [Cell cycle control, cell ...
 841-904 2.29e-17

Spore transcriptional regulator GerE (stand-alone HTH domain) [Cell cycle control, cell division, chromosome partitioning, Transcription];


Pssm-ID: 444607 [Multi-domain]  Cd Length: 76  Bit Score: 77.31  E-value: 2.29e-17
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1902075388 841 VDPLSSRELEVLRLLATSLDGPEIARRLFISLNTLRTHTKNVYAKLGVNRRRDAVTRAGELGLL 904
Cdd:COG5905    10 PSLLTKREREVLELLAEGLTNKEIARQLFISEKTVKNHVSNILRKLGVRNRVQAVVWALRLGLL 73
CitB COG2197
DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains [Signal ...
 798-904 9.11e-16

DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains [Signal transduction mechanisms, Transcription];


Pssm-ID: 441799 [Multi-domain]  Cd Length: 131  Bit Score: 74.54  E-value: 9.11e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 798 VGEGAPVAVLLAAVVERNPSWAyprrLLDALRPESSGASGHGLVdpLSSRELEVLRLLATSLDGPEIARRLFISLNTLRT 877
Cdd:COG2197    30 VGEAADGEEALELLEELRPDVV----LLDIRMPGMDGLEALRRL--LTPREREVLRLLAEGLSNKEIAERLGISERTVKT 103

                          90       100
                  ....*....|....*....|....*..
gi 1902075388 878 HTKNVYAKLGVNRRRDAVTRAGELGLL 904
Cdd:COG2197   104 HVSNILRKLGVRNRTELVLLALRLGLL 130
HTH_LUXR smart00421
helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon
 842-898 5.37e-15

helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon


Pssm-ID: 197715 [Multi-domain]  Cd Length: 58  Bit Score: 69.86  E-value: 5.37e-15
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1902075388  842 DPLSSRELEVLRLLATSLDGPEIARRLFISLNTLRTHTKNVYAKLGVNRRRDAVTRA 898
Cdd:smart00421   2 ASLTPREREVLRLLAEGLTNKEIAERLGISEKTVKTHLSNIMRKLGVRSRTQAVRLA 58
GerE pfam00196
Bacterial regulatory proteins, luxR family;
842-898 6.94e-14

Bacterial regulatory proteins, luxR family;


Pssm-ID: 425517 [Multi-domain]  Cd Length: 57  Bit Score: 66.84  E-value: 6.94e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1902075388 842 DPLSSRELEVLRLLATSLDGPEIARRLFISLNTLRTHTKNVYAKLGVNRRRDAVTRA 898
Cdd:pfam00196   1 DSLSPREREVLRWLAAGKSNKEIADELGISEKTVKVHRSNIMRKLNVHSRVELVRMA 57
LuxR_C_like cd06170
C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix ...
 844-898 5.27e-13

C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many are active as homodimers. Many are two domain proteins in which the DNA binding property of the C-terminal DNA binding domain is modulated by modifications of the N-terminal domain. For example in the case of Lux R which participates in the regulation of gene expression in response to fluctuations in cell-population density (quorum-sensing), a signaling molecule, the pheromone Acyl HSL (N-acyl derivatives of homoserine lactone), binds to the N-terminal domain and leads to LuxR dimerization. For others phophorylation of the N-terminal domain leads to multimerization, for example Escherichia coli NarL and Sinorhizobium melilot FixJ. NarL controls gene expression of many respiratory-related operons when environmental nitrate or nitrite is present under anerobic conditions. FixJ is involved in the transcriptional activation of nitrogen fixation genes. The group also includes small proteins which lack an N-terminal signaling domain, such as Bacillus subtilis GerE. GerE is dimeric and acts in conjunction with sigmaK as an activator or a repressor modulating the expression of various genes in particular those encoding the spore-coat. These LuxR family regulators may share a similar organization of their target binding sites. For example the LuxR dimer binds the lux box, a 20bp inverted repeat, GerE dimers bind two 12bp consensus sequences in inverted orientation having the central four bases overlap, and the NarL dimer binds two 7bp inverted repeats separated by 2 bp.


Pssm-ID: 99777 [Multi-domain]  Cd Length: 57  Bit Score: 64.09  E-value: 5.27e-13
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1902075388 844 LSSRELEVLRLLATSLDGPEIARRLFISLNTLRTHTKNVYAKLGVNRRRDAVTRA 898
Cdd:cd06170     1 LTPREREVLRLLAEGKTNKEIADILGISEKTVKTHLRNIMRKLGVKSRTQLVAYA 55
MalT COG2909
ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT [Transcription];
132-226 3.52e-12

ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT [Transcription];


Pssm-ID: 442153 [Multi-domain]  Cd Length: 184  Bit Score: 65.88  E-value: 3.52e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 132 LVLDDYHLADAPaiadDVAYLVEHLPTDVHVLLGTRADpdlPLARLRARgelVEVRAADLRftLAEVTAYLNDVaGLDLD 211
Cdd:COG2909     2 LVLDDYHLIDDI----HLAFLLRHLPPNLHLVLASRTD---PLARLRAR---LELRADDLR--REEAAALLRRR-LLPLS 68

                          90
                  ....*....|....*
gi 1902075388 212 AREIAVLEDRTEGWV 226
Cdd:COG2909    69 EEDAARLAERTEGWA 83
MalT COG2909
ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT [Transcription];
730-904 2.02e-11

ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT [Transcription];


Pssm-ID: 442153 [Multi-domain]  Cd Length: 184  Bit Score: 63.57  E-value: 2.02e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 730 TTRTayDLLERLRVAAEEDGRTgslieiLSLQALATLAGSETPDVSAALAPleralRLAEPTGHVRVFVGEGAPVAVLLA 809
Cdd:COG2909    31 ASRT--DPLARLRARLELRADD------LRREEAAALLRRRLLPLSEEDAA-----RLAERTEGWARLALDPEEALALLE 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 810 AVVERNPSWAypRRLLDALRPESSGasghglvDPLSSRELEVLRLLATSLDGPEIARRLFISLNTLRTHTKNVYAKLGVN 889
Cdd:COG2909    98 RLLALAEAAG--RLLLRALALRALG-------DREEALAALRRRLLAEGLSNKEIAERLFISVNTVKTHLRNIYRKLGVR 168

                         170
                  ....*....|....*
gi 1902075388 890 RRRDAVTRAGELGLL 904
Cdd:COG2909   169 SRTEAVARARELGLL 183
CsgD COG2771
DNA-binding transcriptional regulator, CsgD family [Transcription];
729-904 2.15e-09

DNA-binding transcriptional regulator, CsgD family [Transcription];


Pssm-ID: 442052 [Multi-domain]  Cd Length: 188  Bit Score: 57.84  E-value: 2.15e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 729 ATTRTAYDLLERLRVAAEEDGRTGSLIEILSLQALATLAGSETPDVSAALAPLERALRLAEPTGHVRVFVGEGAPVAVLL 808
Cdd:COG2771     5 ALALLLLALLLLLLALLALLLLLLLAALLLLLALLLLAALLLLAAAAAALAAALAAALLLGLLLLLLIALLLLLLLLLAL 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 809 AAVVERNPSWAYPRRLLDALRPESSGASGHGLVDP--------LSSRELEVLRLLATSLDGPEIARRLFISLNTLRTHTK 880
Cdd:COG2771    85 LLLLALLALLAALLARLAALLLALALAALLLAALArllarapgLTPREREVLRLLAEGLTLKEIARILGISERTVRTHLK 164

                         170       180
                  ....*....|....*....|....
gi 1902075388 881 NVYAKLGVNRRRDAVTRAGELGLL 904
Cdd:COG2771   165 RIYRKLGVSSRAELVALALRLGLI 188
PRK10100 PRK10100
transcriptional regulator CsgD;
843-900 8.74e-09

transcriptional regulator CsgD;


Pssm-ID: 182241 [Multi-domain]  Cd Length: 216  Bit Score: 56.80  E-value: 8.74e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1902075388 843 PLSSRELEVLRLLATSLDGPEIARRLFISLNTLRTHTKNVYAKLGVNRRRDAVTRAGE 900
Cdd:PRK10100  155 LLTHREKEILNKLRIGASNNEIARSLFISENTVKTHLYNLFKKIAVKNRTQAVSWAND 212
PRK09935 PRK09935
fimbriae biosynthesis transcriptional regulator FimZ;
820-888 5.29e-08

fimbriae biosynthesis transcriptional regulator FimZ;


Pssm-ID: 182154 [Multi-domain]  Cd Length: 210  Bit Score: 54.11  E-value: 5.29e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1902075388 820 YPRRLLDALRPESSGASGHGlVDPLSSRELEVLRLLATSLDGPEIARRLFISLNTLRTHTKNVYAKLGV 888
Cdd:PRK09935  127 FPSETLNYIKSNKCSTNSST-DTVLSNREVTILRYLVSGLSNKEIADQLLLSNKTVSAHKSNIYGKLGL 194
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 454-695 1.04e-06

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 52.69  E-value: 1.04e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 454 LDEREAARVPGAMETYRAALALVAGDPAGTVEHADLAIERAAPGDDLTVAAASALAGLASWAAGDLESAHRAYSGAVEGL 533
Cdd:COG3914     2 AAAALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 534 ERAGNisdvlgcsitlgdLRITQGRLDDARRTYERALRLAAAHeadgaggtggplrgvADMEVGLSEIALEQGHLTEAAA 613
Cdd:COG3914    82 ELAAL-------------LLQALGRYEEALALYRRALALNPDN---------------AEALFNLGNLLLALGRLEEALA 133

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 614 HLGRVAALGERLGLPQLPYrrrvaeARLREAEGDLAGAVALLEEAEKVYvgdysPDVRPLPAQRARVLVAQGRVDEARQW 693
Cdd:COG3914   134 ALRRALALNPDFAEAYLNL------GEALRRLGRLEEAIAALRRALELD-----PDNAEALNNLGNALQDLGRLEEAIAA 202


                  ..
gi 1902075388 694 AR 695
Cdd:COG3914   203 YR 204
COG3903 COG3903
Predicted ATPase [General function prediction only];
284-659 2.22e-05

Predicted ATPase [General function prediction only];


Pssm-ID: 443109 [Multi-domain]  Cd Length: 933  Bit Score: 48.48  E-value: 2.22e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 284 RLGGPLCDAVTGAGDSRSVLEFLERANLFVIPLDDSRQWYRYHHLFADVLRAHLAQERPLEVAGLHRRAAEWYAADGEPE 363
Cdd:COG3903   546 RLAAALAPFWFLRGLLREGRRWLERALAAAGEAAAALAAAAALAAAAAAARAAAAAAAAAAAAAAAAAAAAAAAAAALLL 625

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 364 PAVRHALAAGDVELAADLVERSAIELLRRRQEATVRGWIDAIPDAVVRVRPVLAIAFIGALMSRGEFDTVPDRLAHLEGL 443
Cdd:COG3903   626 LAALAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAAAAAAAAAALAAAAAALAAAAAAAALAA 705

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 444 LADPAAEVVVLDEREAARVPGAMETYRAALALVAGDPAGTVEHADLAIERAAPGDDLTVAAASALAGLASWAAGDLESAH 523
Cdd:COG3903   706 AAAAALAAAAAAAAAAAAAAALLAAAAAAALAAAAAAAALALAAAAAAAAAAAAAAALAAAAAAAALAALLLALAAAAAA 785

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 524 RAYSGAVEGLERAGNISDVLGCSITLGDLRITQGRLDDARRTYERALRLAAAHEADGAGGTGGPLRGVADMEVGLSEIAL 603
Cdd:COG3903   786 LAAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAAALAAALAAAAAAAAAAAAAAAAAAALAAALAAAAAAA 865

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1902075388 604 EQGHLTEAAAHLGRVAALGERLGLPQLPYRRRVAEARLREAEGDLAGAVALLEEAE 659
Cdd:COG3903   866 AAAALAAAAAAAAAAAAALLAAAAAAAAAAAAAAAAAAALAAAAAAAAAAALAAAA 921
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 436-658 3.41e-05

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 47.68  E-value: 3.41e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 436 RLAHLEGLLADPAAEVVVLDEREAARVPGAMETYRAALALVAGDPAGTVEHADLAIERAAPGDDLTVAAASALAGLASWA 515
Cdd:COG3914    11 ALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQA 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 516 AGDLESAHRAYSGAvegLERAGNISDVLgcsITLGDLRITQGRLDDARRTYERALRLAAAHeadgaggtggplrgvADME 595
Cdd:COG3914    91 LGRYEEALALYRRA---LALNPDNAEAL---FNLGNLLLALGRLEEALAALRRALALNPDF---------------AEAY 149

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1902075388 596 VGLSEIALEQGHLTEAAAHLGRVAALgerlgLPQLP--YRRRvaeARLREAEGDLAGAVALLEEA 658
Cdd:COG3914   150 LNLGEALRRLGRLEEAIAALRRALEL-----DPDNAeaLNNL---GNALQDLGRLEEAIAAYRRA 206
PRK10840 PRK10840
transcriptional regulator RcsB; Provisional
 831-889 1.08e-04

transcriptional regulator RcsB; Provisional


Pssm-ID: 182771 [Multi-domain]  Cd Length: 216  Bit Score: 44.44  E-value: 1.08e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1902075388 831 ESSGASGHGlVDPLSSRELEVLRLLATSLDGPEIARRLFISLNTLRTHTKNVYAKLGVN 889
Cdd:PRK10840  139 EKISAGGYG-DKRLSPKESEVLRLFAEGFLVTEIAKKLNRSIKTISSQKKSAMMKLGVE 196
PRK11475 PRK11475
DNA-binding transcriptional activator BglJ; Provisional
 842-889 1.21e-04

DNA-binding transcriptional activator BglJ; Provisional


Pssm-ID: 236915 [Multi-domain]  Cd Length: 207  Bit Score: 44.35  E-value: 1.21e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1902075388 842 DPLSSRELEVLRLLATSLDGPEIARRLFISLNTLRTHTKNVYAKLGVN 889
Cdd:PRK11475  133 RMLSPTEREILRFMSRGYSMPQIAEQLERNIKTIRAHKFNVMSKLGVS 180
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 547-788 2.20e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 43.95  E-value: 2.20e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 547 ITLGDLRITQGRLDDARRTYERALRLAaaheadgaggtggPLRGVADMEvgLSEIALEQGHLTEAAAHLGRVAALGERlg 626
Cdd:COG2956    46 LALGNLYRRRGEYDRAIRIHQKLLERD-------------PDRAEALLE--LAQDYLKAGLLDRAEELLEKLLELDPD-- 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 627 lpQLPYRRRVAEarLREAEGDLAGAVALLEEAEKVyvgdySPDVRPLPAQRARVLVAQGRVDEARQWART-RGLAPDDEL 705
Cdd:COG2956   109 --DAEALRLLAE--IYEQEGDWEKAIEVLERLLKL-----GPENAHAYCELAELYLEQGDYDEAIEALEKaLKLDPDCAR 179

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 706 SYvreyehVTLARVLMHGRDTSGAttrtaydlLERLRVAAEEDGRTGSLIEILSLQALatlagsETPDVSAALAPLERAL 785
Cdd:COG2956   180 AL------LLLAELYLEQGDYEEA--------IAALERALEQDPDYLPALPRLAELYE------KLGDPEEALELLRKAL 239


                  ...
gi 1902075388 786 RLA 788
Cdd:COG2956   240 ELD 242
PRK10651 PRK10651
transcriptional regulator NarL; Provisional
 824-894 5.03e-04

transcriptional regulator NarL; Provisional


Pssm-ID: 182619 [Multi-domain]  Cd Length: 216  Bit Score: 42.32  E-value: 5.03e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1902075388 824 LLDALRPESSGASGHglVDPLSSRELEVLRLLATSLDGPEIARRLFISLNTLRTHTKNVYAKLGVNRRRDA 894
Cdd:PRK10651  138 LAASLRANRATTERD--VNQLTPRERDILKLIAQGLPNKMIARRLDITESTVKVHVKHMLKKMKLKSRVEA 206
FixJ COG4566
DNA-binding response regulator, FixJ family, consists of REC and HTH domains [Signal ...
 840-902 1.07e-03

DNA-binding response regulator, FixJ family, consists of REC and HTH domains [Signal transduction mechanisms, Transcription];


Pssm-ID: 443623 [Multi-domain]  Cd Length: 196  Bit Score: 41.24  E-value: 1.07e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1902075388 840 LVDPLSSRELEVLRLLATSLDGPEIARRLFISLNTLRTHTKNVYAKLGVNRRRDAVTRAGELG 902
Cdd:COG4566   134 RLASLTPREREVLDLVVAGLSNKQIARELGISPRTVEVHRANVMEKLGARSLAELVRLALALG 196
PRK09958 PRK09958
acid-sensing system DNA-binding response regulator EvgA;
797-887 2.10e-03

acid-sensing system DNA-binding response regulator EvgA;


Pssm-ID: 182168 [Multi-domain]  Cd Length: 204  Bit Score: 40.26  E-value: 2.10e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 797 FVGEGAPVAVLLAAVVERNPSWAYPRRLLDalRPESSGASGHGLVDPLSSRELEVLRLLATSLDGPEIARRLFISLNTLR 876
Cdd:PRK09958   99 FVSKKEGMNNIIAAIEAAKNGYCYFPFSLN--RFVGSLTSDQQKLDSLSKQEISVMRYILDGKDNNDIAEKMFISNKTVS 176

                          90
                  ....*....|.
gi 1902075388 877 THTKNVYAKLG 887
Cdd:PRK09958  177 TYKSRLMEKLE 187
COG3903 COG3903
Predicted ATPase [General function prediction only];
164-589 2.18e-03

Predicted ATPase [General function prediction only];


Pssm-ID: 443109 [Multi-domain]  Cd Length: 933  Bit Score: 41.93  E-value: 2.18e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 164 LGTRADPDLPLARLRARGELVEVRAADLRFTLAEVTAYLNDVAGLDLDAREIAVLEDR-----TEGWVAALQLAALSLRG 238
Cdd:COG3903   501 LAERAAAELRGPDQLAWLARLDAEHDNLRAALRWALAHGDAELALRLAAALAPFWFLRgllreGRRWLERALAAAGEAAA 580

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 239 REDPAGFIAGFAGDDRYVVDYLVEEVVRRQPEHVRRFLLETSVLDRLGGPLCDAVTGAGDSRSVLEFLERANLFVIPLDD 318
Cdd:COG3903   581 ALAAAAALAAAAAAARAAAAAAAAAAAAAAAAAAAAAAAAAALLLLAALAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 660

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 319 SRQWYRYHHLFADVLRAHLAQERPLEVAGLHRRAAEWYAADGEPEPAVRHALAAGDVELAADLVERSAIELLRRRQEATV 398
Cdd:COG3903   661 AAAAALAAAAAAAAAAAAAAAAAAAALAAAAAALAAAAAAAALAAAAAAALAAAAAAAAAAAAAAALLAAAAAAALAAAA 740

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 399 RGWIDAIPDAVVRVRPVLAIAFIGALMSRGEFDTVPDRLAHLEGLLADPAAEVVVLDEREAARVPGAMETYRAALALVAG 478
Cdd:COG3903   741 AAAALALAAAAAAAAAAAAAAALAAAAAAAALAALLLALAAAAAALAAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAA 820

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 479 DPAGTVEHADLAIERAAPGDDLTVAAASALAGLASWAAGDLESAHRAYSGAVEGLERAGNISDVLGCSITLGDLRITQGR 558
Cdd:COG3903   821 AAAAAAAAALAAALAAAAAAAAAAAAAAAAAAALAAALAAAAAAAAAAALAAAAAAAAAAAAALLAAAAAAAAAAAAAAA 900

                         410       420       430
                  ....*....|....*....|....*....|.
gi 1902075388 559 LDDARRTYERALRLAAAHEADGAGGTGGPLR 589
Cdd:COG3903   901 AAAALAAAAAAAAAAALAAAAAAAAAAAAAA 931
PRK10360 PRK10360
transcriptional regulator UhpA;
828-889 2.66e-03

transcriptional regulator UhpA;


Pssm-ID: 182408 [Multi-domain]  Cd Length: 196  Bit Score: 39.96  E-value: 2.66e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1902075388 828 LRPESSGASGHGLVDPLSSRELEVLRLLATSLDGPEIARRLFISLNTLRTHTKNVYAKLGVN 889
Cdd:PRK10360  122 LTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAAELGLSPKTVHVHRANLMEKLGVS 183
PRK15369 PRK15369
two component system response regulator;
797-904 2.87e-03

two component system response regulator;


Pssm-ID: 185267 [Multi-domain]  Cd Length: 211  Bit Score: 40.06  E-value: 2.87e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 797 FVGEGAPVAVLLAAV--VERNPSWAYPRRLLDALRPESSGASGhglvDP--LSSRELEVLRLLATSLDGPEIARRLFISL 872
Cdd:PRK15369  103 YVLKKSPQQILLAAIqtVAVGKRYIDPALNREAILALLNADDT----NPplLTPRERQILKLITEGYTNRDIAEQLSISI 178

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1902075388 873 NTLRTHTKNVYAKLGVNRRRDAVTRAGELGLL 904
Cdd:PRK15369  179 KTVETHRLNMMRKLDVHKVAELLNWARRLGLI 210
PRK10403 PRK10403
nitrate/nitrite response regulator protein NarP;
800-896 2.99e-03

nitrate/nitrite response regulator protein NarP;


Pssm-ID: 182431 [Multi-domain]  Cd Length: 215  Bit Score: 40.22  E-value: 2.99e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 800 EGAPVAVLLAAVVERNPSWAYPRRLLDALRPESSGASGHGLVDPLSSRELEVLRLLATSLDGPEIARRLFISLNTLRTHT 879
Cdd:PRK10403  110 DSDPEVLLEAIRAGAKGSKVFSERVNQYLREREMFGAEEDPFSVLTERELDVLHELAQGLSNKQIASVLNISEQTVKVHI 189

                          90
                  ....*....|....*..
gi 1902075388 880 KNVYAKLGVnRRRDAVT 896
Cdd:PRK10403  190 RNLLRKLNV-RSRVAAT 205
COG3903 COG3903
Predicted ATPase [General function prediction only];
424-868 5.95e-03

Predicted ATPase [General function prediction only];


Pssm-ID: 443109 [Multi-domain]  Cd Length: 933  Bit Score: 40.39  E-value: 5.95e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 424 LMSRGEFDTVPDRLAHLEGLLADPAAEVVVLDEREAARVPGAMETYRAALALVAGDPAGTVEHADLAIERAAPGDDLTVA 503
Cdd:COG3903   481 LAEAGERAAARRRHADYYLALAERAAAELRGPDQLAWLARLDAEHDNLRAALRWALAHGDAELALRLAAALAPFWFLRGL 560

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 504 AASALAGLASWAAGDLESAHRAYSGAVEGLERAGNISDVLGCSITLGDLRITQGRLDDARRTYERALRLAAAHEADGAGG 583
Cdd:COG3903   561 LREGRRWLERALAAAGEAAAALAAAAALAAAAAAARAAAAAAAAAAAAAAAAAAAAAAAAAALLLLAALAAAAAAAAAAA 640

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 584 TGGPLRGVADMEVGLSEIALEQGHLTEAAAHLGRVAALGERLGLPQLPYRRRVAEARLREAEGDLAGAVALLEEAEKVYV 663
Cdd:COG3903   641 AAAAAAAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAAAAAAAAAALAAAAAALAAAAAAAALAAAAAAALAAAAAAAAA 720

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 664 GDYSPDVRPLPAQRARVLVAQGRVDEARQWARTRGLAPDDELSYVREYEHVTLARVLMHGRDTSGATTRTAYDLLERLRV 743
Cdd:COG3903   721 AAAAAALLAAAAAAALAAAAAAAALALAAAAAAAAAAAAAAALAAAAAAAALAALLLALAAAAAALAAAAAAAAAAAAAA 800

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1902075388 744 AAEEDGRTGSLIEILSLQALATLAGSETPDVSAALAPLERALRLAEPTGHVRVFVGEGAPVAVLLAAVVERNPSWAYPRR 823
Cdd:COG3903   801 AAAAAAAAAAAAAAALAAAAAAAAAAAAALAAALAAAAAAAAAAAAAAAAAAALAAALAAAAAAAAAAALAAAAAAAAAA 880

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*
gi 1902075388 824 LLDALRPESSGASGHGLVDPLSSRELEVLRLLATSLDGPEIARRL 868
Cdd:COG3903   881 AAALLAAAAAAAAAAAAAAAAAAALAAAAAAAAAAALAAAAAAAA 925
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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