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Conserved domains on  [gi|2425517910|gb|KAJ3615406|]
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hypothetical protein NHX12_016105, partial [Muraenolepis orangiensis]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG4076 super family cl44002
Predicted RNA methylase [General function prediction only];
151-294 7.64e-29

Predicted RNA methylase [General function prediction only];


The actual alignment was detected with superfamily member COG4076:

Pssm-ID: 443253 [Multi-domain]  Cd Length: 230  Bit Score: 112.82  E-value: 7.64e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2425517910 151 LVERWHFLMLNDRGRNQKYQQAIQKAVERGcNTVLDIGTGTGILGMCAKKAGAASVFACEWSKTMYELACEVVTANGMKG 230
Cdd:COG4076     7 FVPRWHHPMLNDVERNDAFKAAIERVVKPG-DVVLDIGTGSGLLSMLAARAGAKKVYAVEVNPDIAAVARRIIAANGLSD 85

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2425517910 231 GINILHKKSLDMEVPKDIPHRVS-----------LVNISHDTMSPEASETGRVIPAGATVFGMAVESLEVRRHHR 294
Cdd:COG4076    86 RITVINADATDLDLPEKADVIISemldtalldegQVPILNHARKRLLKPGGRIIPERITNAAQPVESPVDAEGFE 160
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 84-143 1.18e-10

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


:

Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 59.59  E-value: 1.18e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2425517910  84 GRIEELLHSFGLALEVFPDDEIILNSLGELLFRLGFRDEAASHFHKALKLKPDYPEAREN 143
Cdd:COG5010    68 GDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSN 127
 
Name Accession Description Interval E-value
COG4076 COG4076
Predicted RNA methylase [General function prediction only];
151-294 7.64e-29

Predicted RNA methylase [General function prediction only];


Pssm-ID: 443253 [Multi-domain]  Cd Length: 230  Bit Score: 112.82  E-value: 7.64e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2425517910 151 LVERWHFLMLNDRGRNQKYQQAIQKAVERGcNTVLDIGTGTGILGMCAKKAGAASVFACEWSKTMYELACEVVTANGMKG 230
Cdd:COG4076     7 FVPRWHHPMLNDVERNDAFKAAIERVVKPG-DVVLDIGTGSGLLSMLAARAGAKKVYAVEVNPDIAAVARRIIAANGLSD 85

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2425517910 231 GINILHKKSLDMEVPKDIPHRVS-----------LVNISHDTMSPEASETGRVIPAGATVFGMAVESLEVRRHHR 294
Cdd:COG4076    86 RITVINADATDLDLPEKADVIISemldtalldegQVPILNHARKRLLKPGGRIIPERITNAAQPVESPVDAEGFE 160
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 84-143 1.18e-10

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 59.59  E-value: 1.18e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2425517910  84 GRIEELLHSFGLALEVFPDDEIILNSLGELLFRLGFRDEAASHFHKALKLKPDYPEAREN 143
Cdd:COG5010    68 GDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSN 127
prmA PRK00517
50S ribosomal protein L11 methyltransferase;
171-209 2.59e-07

50S ribosomal protein L11 methyltransferase;


Pssm-ID: 234786 [Multi-domain]  Cd Length: 250  Bit Score: 51.31  E-value: 2.59e-07
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 2425517910 171 QAIQKAVERGCnTVLDIGTGTGILGMCAKKAGAASVFAC 209
Cdd:PRK00517  111 EALEKLVLPGK-TVLDVGCGSGILAIAAAKLGAKKVLAV 148
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 183-236 7.87e-05

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 41.65  E-value: 7.87e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2425517910 183 TVLDIGTGTGILGMCAKKAGAASVFACEWSKTMYELACEVVTANGMKgGINILH 236
Cdd:cd02440     1 RVLDLGCGTGALALALASGPGARVTGVDISPVALELARKAAAALLAD-NVEVLK 53
PrmA pfam06325
Ribosomal protein L11 methyltransferase (PrmA); This family consists of several Ribosomal ...
 171-208 1.06e-04

Ribosomal protein L11 methyltransferase (PrmA); This family consists of several Ribosomal protein L11 methyltransferase (EC:2.1.1.-) sequences.


Pssm-ID: 428888 [Multi-domain]  Cd Length: 294  Bit Score: 43.79  E-value: 1.06e-04
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 2425517910 171 QAIQKAVERGCnTVLDIGTGTGILGMCAKKAGAASVFA 208
Cdd:pfam06325 153 EALERLVKPGE-SVLDVGCGSGILAIAALKLGAKKVVG 189
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
 96-202 2.11e-04

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 42.32  E-value: 2.11e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2425517910  96 ALEVFPDDEIILNSLGELLFRLGFRDEAASHFHKALKLKPDYPEARENFYRaanwlverwhFLMlndrgRNQKYQQAIQ- 174
Cdd:TIGR02521  57 ALEHDPDDYLAYLALALYYQQLGELEKAEDSFRRALTLNPNNGDVLNNYGT----------FLC-----QQGKYEQAMQq 121

                          90       100       110
                  ....*....|....*....|....*....|...
gi 2425517910 175 --KAVERgcntvLDIGTGTGIL---GMCAKKAG 202
Cdd:TIGR02521 122 feQAIED-----PLYPQPARSLenaGLCALKAG 149
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 106-136 6.61e-04

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 36.73  E-value: 6.61e-04
                          10        20        30
                  ....*....|....*....|....*....|.
gi 2425517910 106 ILNSLGELLFRLGFRDEAASHFHKALKLKPD 136
Cdd:pfam07719   3 ALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 82-136 3.09e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 39.15  E-value: 3.09e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2425517910  82 SEGRIEELLHSFGLALEVFPDDEIILNSLGELLFRLGFRDEAASHFHKALKLKPD 136
Cdd:cd24142    12 DQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPD 66
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 96-149 4.84e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 39.30  E-value: 4.84e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2425517910  96 ALEVFPDDEIILNSLGELLFRLGFRDEAASHFHKALKLKPDYPEARENF---YRAAN 149
Cdd:TIGR02917 829 ALKLAPNIPAILDTLGWLLVEKGEADRALPLLRKAVNIAPEAAAIRYHLalaLLATG 885
 
Name Accession Description Interval E-value
COG4076 COG4076
Predicted RNA methylase [General function prediction only];
151-294 7.64e-29

Predicted RNA methylase [General function prediction only];


Pssm-ID: 443253 [Multi-domain]  Cd Length: 230  Bit Score: 112.82  E-value: 7.64e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2425517910 151 LVERWHFLMLNDRGRNQKYQQAIQKAVERGcNTVLDIGTGTGILGMCAKKAGAASVFACEWSKTMYELACEVVTANGMKG 230
Cdd:COG4076     7 FVPRWHHPMLNDVERNDAFKAAIERVVKPG-DVVLDIGTGSGLLSMLAARAGAKKVYAVEVNPDIAAVARRIIAANGLSD 85

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2425517910 231 GINILHKKSLDMEVPKDIPHRVS-----------LVNISHDTMSPEASETGRVIPAGATVFGMAVESLEVRRHHR 294
Cdd:COG4076    86 RITVINADATDLDLPEKADVIISemldtalldegQVPILNHARKRLLKPGGRIIPERITNAAQPVESPVDAEGFE 160
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 84-143 1.18e-10

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 59.59  E-value: 1.18e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2425517910  84 GRIEELLHSFGLALEVFPDDEIILNSLGELLFRLGFRDEAASHFHKALKLKPDYPEAREN 143
Cdd:COG5010    68 GDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSN 127
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 32-179 1.75e-10

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 58.66  E-value: 1.75e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2425517910  32 LESAQQCLSNQDYGTAFVYYLLVLNLAPVlKHFARESFRFTLFKivdewesEGRIEELLHSFGLALEVFPDDEIILNSLG 111
Cdd:COG4783     8 YALAQALLLAGDYDEAEALLEKALELDPD-NPEAFALLGEILLQ-------LGDLDEAIVLLHEALELDPDEPEARLNLG 79

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2425517910 112 ELLFRLGFRDEAASHFHKALKLKPDYPEARenfYRAANwlverwhflMLNDRGRNQKYQQAIQKAVER 179
Cdd:COG4783    80 LALLKAGDYDEALALLEKALKLDPEHPEAY---LRLAR---------AYRALGRPDEAIAALEKALEL 135
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 84-179 1.32e-09

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 60.01  E-value: 1.32e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2425517910  84 GRIEELLHSFGLALEVFPDDEIILNSLGELLFRLGFRDEAASHFHKALKLKPDYPEArenfyraanwlverWHFL--MLN 161
Cdd:COG3914    92 GRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEA--------------YLNLgeALR 157

                          90
                  ....*....|....*...
gi 2425517910 162 DRGRNQKYQQAIQKAVER 179
Cdd:COG3914   158 RLGRLEEAIAALRRALEL 175
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
43-143 3.14e-09

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 57.32  E-value: 3.14e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2425517910  43 DYGTAFVYYLLVLNLAPvlkHFAResfrfTLFKIVDEWESEGRIEELLHSFGLALEVFPDDEIILNSLGELLFRLGFRDE 122
Cdd:COG0457    57 RYEEALADYEQALELDP---DDAE-----ALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDE 128

                          90       100
                  ....*....|....*....|.
gi 2425517910 123 AASHFHKALKLKPDYPEAREN 143
Cdd:COG0457   129 AIEAYERALELDPDDADALYN 149
PrmA COG2264
Ribosomal protein L11 methylase PrmA [Translation, ribosomal structure and biogenesis];
171-236 3.97e-09

Ribosomal protein L11 methylase PrmA [Translation, ribosomal structure and biogenesis];


Pssm-ID: 441865 [Multi-domain]  Cd Length: 284  Bit Score: 57.11  E-value: 3.97e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2425517910 171 QAIQKAVERGCnTVLDIGTGTGILGMCAKKAGAASVFAC---EWSktmYELACEVVTANGMKGGINILH 236
Cdd:COG2264   140 EALEKLLKPGK-TVLDVGCGSGILAIAAAKLGAKRVLAVdidPVA---VEAARENAELNGVEDRIEVVL 204
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
84-178 5.95e-09

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 56.55  E-value: 5.95e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2425517910  84 GRIEELLHSFGLALEVFPDDEIILNSLGELLFRLGFRDEAASHFHKALKLKPDYPEARENfyRAanwlverwhfLMLNDR 163
Cdd:COG0457    56 GRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYN--LG----------LALLEL 123

                          90
                  ....*....|....*
gi 2425517910 164 GRNQKYQQAIQKAVE 178
Cdd:COG0457   124 GRYDEAIEAYERALE 138
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
80-179 7.92e-09

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 52.48  E-value: 7.92e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2425517910  80 WESEGRIEELLHSFGLALEVFPDDEIILNSLGELLFRLGFRDEAAShFHKALKLKPDYPEARENFYRAanwlverwhflm 159
Cdd:COG3063     2 YLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAEL------------ 68

                          90       100
                  ....*....|....*....|
gi 2425517910 160 LNDRGRNQKYQQAIQKAVER 179
Cdd:COG3063    69 LLELGDYDEALAYLERALEL 88
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 81-175 1.10e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 57.31  E-value: 1.10e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2425517910  81 ESEGRIEELLHSFGLALEVFPDDEIILNSLGELLFRLGFRDEAASHFHKALKLKPDYPEARenfyraANWLVERWHFLML 160
Cdd:COG3914   157 RRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAH------SNLLFALRQACDW 230

                          90
                  ....*....|....*
gi 2425517910 161 NDRGRNQKYQQAIQK 175
Cdd:COG3914   231 EVYDRFEELLAALAR 245
TrmN6 COG4123
tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) ...
 179-236 1.19e-08

tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) A37 N6-methylase TrmN6 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 443299 [Multi-domain]  Cd Length: 238  Bit Score: 55.15  E-value: 1.19e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2425517910 179 RGCNTVLDIGTGTGILG-MCAKKAGAASVFACEWSKTMYELACEVVTANGMKGGINILH 236
Cdd:COG4123    36 KKGGRVLDLGTGTGVIAlMLAQRSPGARITGVEIQPEAAELARRNVALNGLEDRITVIH 94
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
80-174 1.47e-08

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 55.01  E-value: 1.47e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2425517910  80 WESEGRIEELLHSFGLALEVFPDDEIILNSLGELLFRLGFRDEAASHFHKALKLKPDYPEARENfyRAanwlverwhfLM 159
Cdd:COG0457    18 YRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNN--LG----------LA 85

                          90
                  ....*....|....*....
gi 2425517910 160 LNDRGRNQK----YQQAIQ 174
Cdd:COG0457    86 LQALGRYEEaledYDKALE 104
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
101-179 3.82e-08

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 53.77  E-value: 3.82e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2425517910 101 PDDEIILNSLGELLFRLGFRDEAASHFHKALKLKPDYPEARenFYRAANWLverwhflmlndrgRNQKYQQAIQ---KAV 177
Cdd:COG4785    70 PDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAY--NNRGLAYL-------------LLGDYDAALEdfdRAL 134


                  ..
gi 2425517910 178 ER 179
Cdd:COG4785   135 EL 136
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 84-174 1.10e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 50.39  E-value: 1.10e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2425517910  84 GRIEELLHSFGLALEVFPDDEIILNSLGELLFRLGFRDEAASHFHKALKLKPDYPEARenFYRAANWLverwhflmlndr 163
Cdd:COG4235    31 GRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEAL--YLLGLAAF------------ 96

                          90
                  ....*....|.
gi 2425517910 164 gRNQKYQQAIQ 174
Cdd:COG4235    97 -QQGDYAEAIA 106
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
80-175 2.20e-07

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 51.45  E-value: 2.20e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2425517910  80 WESEGRIEELLHSFGLALEVFPDDEIILNSLGELLFRLGFRDEAASHFHKALKLKPDYPEAREN---------------- 143
Cdd:COG4785    83 YDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNrgialyylgryelaia 162

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 2425517910 144 ----FYRAANWLVERWHFLMLNDrgRNQKYQQAIQK 175
Cdd:COG4785   163 dlekALELDPNDPERALWLYLAE--RKLDPEKALAL 196
prmA PRK00517
50S ribosomal protein L11 methyltransferase;
171-209 2.59e-07

50S ribosomal protein L11 methyltransferase;


Pssm-ID: 234786 [Multi-domain]  Cd Length: 250  Bit Score: 51.31  E-value: 2.59e-07
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 2425517910 171 QAIQKAVERGCnTVLDIGTGTGILGMCAKKAGAASVFAC 209
Cdd:PRK00517  111 EALEKLVLPGK-TVLDVGCGSGILAIAAAKLGAKKVLAV 148
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 32-143 8.93e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 47.03  E-value: 8.93e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2425517910  32 LESAQQCLSNQDYGTAFVYYLLVLNLAPvlkhfarESFRfTLFKIVDEWESEGRIEELLHSFGLALEVFPDDEIILNSLG 111
Cdd:COG2956    12 YFKGLNYLLNGQPDKAIDLLEEALELDP-------ETVE-AHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELA 83

                          90       100       110
                  ....*....|....*....|....*....|..
gi 2425517910 112 ELLFRLGFRDEAASHFHKALKLKPDYPEAREN 143
Cdd:COG2956    84 QDYLKAGLLDRAEELLEKLLELDPDDAEALRL 115
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
97-178 1.05e-05

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 46.54  E-value: 1.05e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2425517910  97 LEVFPDDEIILNSLGELLFRLGFRDEAASHFHKALKLKPDYPEArenFYRAANWLVERwhflmlndrgrnQKYQQAI--- 173
Cdd:COG0457     1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEA---LYNLGLAYLRL------------GRYEEALady 65


                  ....*
gi 2425517910 174 QKAVE 178
Cdd:COG0457    66 EQALE 70
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 83-179 1.47e-05

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 43.83  E-value: 1.47e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2425517910  83 EGRIEELLHSFGLALEVFPDDEIILNS---LGELLFRLGFRDEAASHFHKALKLKPDYPEARENFYRAANWLVErwhflm 159
Cdd:COG1729     6 AGDYDEAIAAFKAFLKRYPNSPLAPDAlywLGEAYYALGDYDEAAEAFEKLLKRYPDSPKAPDALLKLGLSYLE------ 79

                          90       100
                  ....*....|....*....|
gi 2425517910 160 lndRGRNQKYQQAIQKAVER 179
Cdd:COG1729    80 ---LGDYDKARATLEELIKK 96
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
84-174 5.15e-05

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 44.61  E-value: 5.15e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2425517910  84 GRIEELLHSFGLALEVFPDDEIILNSLGELLFRLGFRDEAASHFHKALKLKPDYPEARENFYRAANWLVERWHFLMLNDR 163
Cdd:COG0457   124 GRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLAL 203

                          90
                  ....*....|.
gi 2425517910 164 GRNQKYQQAIQ 174
Cdd:COG0457   204 EQALRKKLAIL 214
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
39-136 5.41e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 41.69  E-value: 5.41e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2425517910  39 LSNQDYGTAFVYYLLVLNLAPvlkhfareSFRFTLFKIVDEWESEGRIEELLhSFGLALEVFPDDEIILNSLGELLFRLG 118
Cdd:COG3063     3 LKLGDLEEAEEYYEKALELDP--------DNADALNNLGLLLLEQGRYDEAI-ALEKALKLDPNNAEALLNLAELLLELG 73

                          90
                  ....*....|....*...
gi 2425517910 119 FRDEAASHFHKALKLKPD 136
Cdd:COG3063    74 DYDEALAYLERALELDPS 91
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 84-135 5.93e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 43.03  E-value: 5.93e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2425517910  84 GRIEELLHSFGLALEVFPDDEIILNSLGELLFRLGFRDEAASHFHKALKLKP 135
Cdd:COG5010   102 GDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 183-236 7.87e-05

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 41.65  E-value: 7.87e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2425517910 183 TVLDIGTGTGILGMCAKKAGAASVFACEWSKTMYELACEVVTANGMKgGINILH 236
Cdd:cd02440     1 RVLDLGCGTGALALALASGPGARVTGVDISPVALELARKAAAALLAD-NVEVLK 53
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 84-137 8.73e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 42.10  E-value: 8.73e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2425517910  84 GRIEELLHSFGLALEVFPDDEIILNSLGELLFRLGFRDEAASHFHKALKLKPDY 137
Cdd:COG4783    86 GDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 39-179 9.65e-05

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 43.95  E-value: 9.65e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2425517910  39 LSNQDYGTAFVYYLLVLNLAPVLKHFaresfrftLFKIVDEWESEGRIEELLHSFGLALEVFPDDEIILNSLGELLFRLG 118
Cdd:COG2956   121 EQEGDWEKAIEVLERLLKLGPENAHA--------YCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQG 192

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2425517910 119 FRDEAASHFHKALKLKPDYPEARENFYRAANWLverwhflmlndrGRNQKYQQAIQKAVER 179
Cdd:COG2956   193 DYEEAIAALERALEQDPDYLPALPRLAELYEKL------------GDPEEALELLRKALEL 241
PrmA pfam06325
Ribosomal protein L11 methyltransferase (PrmA); This family consists of several Ribosomal ...
 171-208 1.06e-04

Ribosomal protein L11 methyltransferase (PrmA); This family consists of several Ribosomal protein L11 methyltransferase (EC:2.1.1.-) sequences.


Pssm-ID: 428888 [Multi-domain]  Cd Length: 294  Bit Score: 43.79  E-value: 1.06e-04
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 2425517910 171 QAIQKAVERGCnTVLDIGTGTGILGMCAKKAGAASVFA 208
Cdd:pfam06325 153 EALERLVKPGE-SVLDVGCGSGILAIAALKLGAKKVVG 189
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 96-179 1.63e-04

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 41.14  E-value: 1.63e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2425517910  96 ALEVFPDDEIILNSLGELLFRLGFRDEAASHFHKALKLKPDYPEARenFYRAAnwlverwhflMLNDRGRNQKYQQAIQK 175
Cdd:COG4235     9 ALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADAL--LDLAE----------ALLAAGDTEEAEELLER 76


                  ....
gi 2425517910 176 AVER 179
Cdd:COG4235    77 ALAL 80
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 35-141 1.73e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 43.18  E-value: 1.73e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2425517910  35 AQQCLSNQDYGTAFVYYLLVLNLAPvlkhfARESFRFTLFKIvdeWESEGRIEELLHSFGLALEVFPDDEIILNSLGELL 114
Cdd:COG2956    83 AQDYLKAGLLDRAEELLEKLLELDP-----DDAEALRLLAEI---YEQEGDWEKAIEVLERLLKLGPENAHAYCELAELY 154

                          90       100
                  ....*....|....*....|....*..
gi 2425517910 115 FRLGFRDEAASHFHKALKLKPDYPEAR 141
Cdd:COG2956   155 LEQGDYDEAIEALEKALKLDPDCARAL 181
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
 96-202 2.11e-04

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 42.32  E-value: 2.11e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2425517910  96 ALEVFPDDEIILNSLGELLFRLGFRDEAASHFHKALKLKPDYPEARENFYRaanwlverwhFLMlndrgRNQKYQQAIQ- 174
Cdd:TIGR02521  57 ALEHDPDDYLAYLALALYYQQLGELEKAEDSFRRALTLNPNNGDVLNNYGT----------FLC-----QQGKYEQAMQq 121

                          90       100       110
                  ....*....|....*....|....*....|...
gi 2425517910 175 --KAVERgcntvLDIGTGTGIL---GMCAKKAG 202
Cdd:TIGR02521 122 feQAIED-----PLYPQPARSLenaGLCALKAG 149
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 32-153 2.25e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 42.79  E-value: 2.25e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2425517910  32 LESAQQCLSNQDYGTAFVYYLLVLNLAPvlkHFAResfrfTLFKIVDEWESEGRIEELLHSFGLALEVFPDDEIILNSLG 111
Cdd:COG2956   148 CELAELYLEQGDYDEAIEALEKALKLDP---DCAR-----ALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLA 219

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2425517910 112 ELLFRLGFRDEAASHFHKALKLKPDYP---------EARENFYRAANWLVE 153
Cdd:COG2956   220 ELYEKLGDPEEALELLRKALELDPSDDlllaladllERKEGLEAALALLER 270
COG2263 COG2263
Predicted RNA methylase [General function prediction only];
183-219 6.40e-04

Predicted RNA methylase [General function prediction only];


Pssm-ID: 441864 [Multi-domain]  Cd Length: 199  Bit Score: 40.66  E-value: 6.40e-04
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 2425517910 183 TVLDIGTGTGILGMCAKKAGAASVFACEWSKTMYELA 219
Cdd:COG2263    48 TVLDLGCGTGMLAIGAALLGAKKVVGVDIDPEALEIA 84
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 106-136 6.61e-04

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 36.73  E-value: 6.61e-04
                          10        20        30
                  ....*....|....*....|....*....|.
gi 2425517910 106 ILNSLGELLFRLGFRDEAASHFHKALKLKPD 136
Cdd:pfam07719   3 ALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 184-229 8.71e-04

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 38.31  E-value: 8.71e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 2425517910 184 VLDIGTGTGILGMCAKKAGAASVFACEWSKTMYELACEVVTANGMK 229
Cdd:pfam13649   1 VLDLGCGTGRLTLALARRGGARVTGVDLSPEMLERARERAAEAGLN 46
PRK14968 PRK14968
putative methyltransferase; Provisional
 173-210 1.03e-03

putative methyltransferase; Provisional


Pssm-ID: 237872 [Multi-domain]  Cd Length: 188  Bit Score: 39.88  E-value: 1.03e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 2425517910 173 IQKAVERGCNTVLDIGTGTGILGMCAKKAGaASVFACE 210
Cdd:PRK14968   16 AENAVDKKGDRVLEVGTGSGIVAIVAAKNG-KKVVGVD 52
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 73-142 2.21e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 37.66  E-value: 2.21e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2425517910  73 LFKIVDEWESEGRIEELLHSFGLALEVFPDDEIILNSL---GELLFRLGFRDEAASHFHKALKLKPDYPEARE 142
Cdd:COG1729    33 LYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKAPDALlklGLSYLELGDYDKARATLEELIKKYPDSEAAKE 105
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 84-141 2.59e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 37.68  E-value: 2.59e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2425517910  84 GRIEELLHSFGLALEVFPDDEIILNSLGELLFRLGFRDEAASHFHKALKLKPDYPEAR 141
Cdd:COG4235    65 GDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPAR 122
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 82-136 3.09e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 39.15  E-value: 3.09e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2425517910  82 SEGRIEELLHSFGLALEVFPDDEIILNSLGELLFRLGFRDEAASHFHKALKLKPD 136
Cdd:cd24142    12 DQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPD 66
TPR_1 pfam00515
Tetratricopeptide repeat;
106-137 3.59e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 34.70  E-value: 3.59e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 2425517910 106 ILNSLGELLFRLGFRDEAASHFHKALKLKPDY 137
Cdd:pfam00515   3 ALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
113-174 4.25e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 36.30  E-value: 4.25e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2425517910 113 LLFRLGFRDEAASHFHKALKLKPDYPEARENFYRAanwlverwhFLMLNDRGRNQKYQQAIQ 174
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLL---------LLEQGRYDEAIALEKALK 53
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 96-149 4.84e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 39.30  E-value: 4.84e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2425517910  96 ALEVFPDDEIILNSLGELLFRLGFRDEAASHFHKALKLKPDYPEARENF---YRAAN 149
Cdd:TIGR02917 829 ALKLAPNIPAILDTLGWLLVEKGEADRALPLLRKAVNIAPEAAAIRYHLalaLLATG 885
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 83-141 5.14e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 39.30  E-value: 5.14e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2425517910  83 EGRIEELLHSFGLALEVFPDDEIILNSLGELLFRLGFRDEAASHFHKALKLKPDYPEAR 141
Cdd:TIGR02917 342 LGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAAR 400
HemK COG2890
Methylase of polypeptide chain release factors [Translation, ribosomal structure and ...
 170-236 5.19e-03

Methylase of polypeptide chain release factors [Translation, ribosomal structure and biogenesis];


Pssm-ID: 442135 [Multi-domain]  Cd Length: 282  Bit Score: 38.59  E-value: 5.19e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2425517910 170 QQAIQKAVERGCNTVLDIGTGTGILG-MCAKKAGAASVFACEWSKTMYELACEVVTANGMKGGINILH 236
Cdd:COG2890   102 ELALALLPAGAPPRVLDLGTGSGAIAlALAKERPDARVTAVDISPDALAVARRNAERLGLEDRVRFLQ 169
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 113-179 7.55e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 36.86  E-value: 7.55e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2425517910 113 LLFRLGFRDEAASHFHKALKLKPDYPEARENFYRAanwlverwhflmLNDRGRNQKYQQAIQKAVER 179
Cdd:COG5010    63 LYNKLGDFEESLALLEQALQLDPNNPELYYNLALL------------YSRSGDKDEAKEYYEKALAL 117
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 169-227 9.72e-03

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 36.51  E-value: 9.72e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2425517910 169 YQQAIQKAVERGCNTVLDIGTGTGILGMCAKKAGaASVFACEWSKTMYELACEVVTANG 227
Cdd:COG2226    11 REALLAALGLRPGARVLDLGCGTGRLALALAERG-ARVTGVDISPEMLELARERAAEAG 68
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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