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Conserved domains on  [gi|818609379|gb|KKS58251|]
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MAG: hypothetical protein UV22_C0002G0014 [Parcubacteria group bacterium GW2011_GWA2_42_35]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG0645 COG0645
Predicted kinase, contains AAA domain [General function prediction only];
54-162 1.04e-19

Predicted kinase, contains AAA domain [General function prediction only];


:

Pssm-ID: 440410 [Multi-domain]  Cd Length: 164  Bit Score: 83.04  E-value: 1.04e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609379  54 IVAVIGLVGSGKSSVAHELAKYIGATVIKGDDIRIELRKQS----EKYKQARTIAENA----AVEIVKQGGNVILDSDFV 125
Cdd:COG0645    1 LILVCGLPGSGKSTLARALAERLGAVRLRSDVVRKRLFGAGlaplERSPEATARTYARllalARELLAAGRSVILDATFL 80

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 818609379 126 DEKKRASVREKARKAGVRLVFVRTHCDLDVMVGRVLT 162
Cdd:COG0645   81 RRAQREAFRALAEEAGAPFVLIWLDAPEEVLRERLEA 117
YlqF_related_GTPase super family cl49605
Circularly permuted YlqF-related GTPases; These proteins are found in bacteria, eukaryotes, ...
 8-80 9.40e-03

Circularly permuted YlqF-related GTPases; These proteins are found in bacteria, eukaryotes, and archaea. They all exhibit a circular permutation of the GTPase signature motifs so that the order of the conserved G box motifs is G4-G5-G1-G2-G3, with G4 and G5 being permuted from the C-terminal region of proteins in the Ras superfamily to the N-terminus of YlqF-related GTPases.


The actual alignment was detected with superfamily member cd01849:

Pssm-ID: 483945 [Multi-domain]  Cd Length: 146  Bit Score: 35.44  E-value: 9.40e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 818609379   8 LIEFIPLSIIKIImecKRKLTKKESTAQNAFMAKLDIKQRKTKEPVIVAVIGLVGSGKSSVAHELAKYIGATV 80
Cdd:cd01849   50 VAELSELYGTKTF---FISATNGQGILKLKAEITKQKLKLKYKKGIRVGVVGLPNVGKSSFINALLNKFKLKV 119
 
Name Accession Description Interval E-value
COG0645 COG0645
Predicted kinase, contains AAA domain [General function prediction only];
54-162 1.04e-19

Predicted kinase, contains AAA domain [General function prediction only];


Pssm-ID: 440410 [Multi-domain]  Cd Length: 164  Bit Score: 83.04  E-value: 1.04e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609379  54 IVAVIGLVGSGKSSVAHELAKYIGATVIKGDDIRIELRKQS----EKYKQARTIAENA----AVEIVKQGGNVILDSDFV 125
Cdd:COG0645    1 LILVCGLPGSGKSTLARALAERLGAVRLRSDVVRKRLFGAGlaplERSPEATARTYARllalARELLAAGRSVILDATFL 80

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 818609379 126 DEKKRASVREKARKAGVRLVFVRTHCDLDVMVGRVLT 162
Cdd:COG0645   81 RRAQREAFRALAEEAGAPFVLIWLDAPEEVLRERLEA 117
AAA_33 pfam13671
AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the ...
 55-177 5.55e-13

AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.


Pssm-ID: 463952 [Multi-domain]  Cd Length: 143  Bit Score: 64.25  E-value: 5.55e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609379   55 VAVIGLVGSGKSSVAHELAKYIGATVIKGDDIR----IELRKQSEKYKQARTIAENAAVEIV----KQGGNVILDSDFVD 126
Cdd:pfam13671   2 ILLVGLPGSGKSTLARRLLEELGAVRLSSDDERkrlfGEGRPSISYYTDATDRTYERLHELArialRAGRPVILDATNLR 81

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 818609379  127 EKKRASVREKARKAGVRLVFVRTHCDLDVMVGRVlTATYHNRVDDFFGGAE 177
Cdd:pfam13671  82 RDERARLLALAREYGVPVRIVVFEAPEEVLRERL-AARARAGGDPSDVPEE 131
GntK cd02021
Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting ...
 54-166 9.45e-08

Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits.


Pssm-ID: 238979 [Multi-domain]  Cd Length: 150  Bit Score: 49.94  E-value: 9.45e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609379  54 IVAVIGLVGSGKSSVAHELAKYIGATVIKGDDirieLRKQSEKYKQAR--------------TIAENAAVEIVKQGGNVI 119
Cdd:cd02021    1 IIVVMGVSGSGKSTVGKALAERLGAPFIDGDD----LHPPANIAKMAAgiplndedrwpwlqALTDALLAKLASAGEGVV 76

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 818609379 120 LDSDFvdEKKRasVREKARK--AGVRLVFVRTHCDLDVMVGRVLTATYH 166
Cdd:cd02021   77 VACSA--LKRI--YRDILRGgaANPRVRFVHLDGPREVLAERLAARKGH 121
pseT PHA02530
polynucleotide kinase; Provisional
 54-159 9.18e-07

polynucleotide kinase; Provisional


Pssm-ID: 222856 [Multi-domain]  Cd Length: 300  Bit Score: 48.87  E-value: 9.18e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609379  54 IVAVIGLVGSGKSSVAHELA-KYIGATVIKGDDIRIEL---RKQSE-KYKQAR----TIAE-NAAVEIVKQGGNVILDSD 123
Cdd:PHA02530   4 IILTVGVPGSGKSTWAREFAaKNPKAVNVNRDDLRQSLfghGEWGEyKFTKEKedlvTKAQeAAALAALKSGKSVIISDT 83

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 818609379 124 FVDEKKRASVREKARKAGVRLVFVRTHCDLDVMVGR 159
Cdd:PHA02530  84 NLNPERRRKWKELAKELGAEFEEKVFDVPVEELVKR 119
therm_gnt_kin TIGR01313
carbohydrate kinase, thermoresistant glucokinase family; This model represents a subfamily of ...
 57-85 6.73e-04

carbohydrate kinase, thermoresistant glucokinase family; This model represents a subfamily of proteins that includes thermoresistant and thermosensitve isozymes of gluconate kinase (gluconokinase) in E. coli and other related proteins; members of this family are often named by similarity to the thermostable isozyme. These proteins show homology to shikimate kinases and adenylate kinases but not to gluconate kinases from the FGGY family of carbohydrate kinases.


Pssm-ID: 273551  Cd Length: 163  Bit Score: 39.31  E-value: 6.73e-04
                          10        20
                  ....*....|....*....|....*....
gi 818609379   57 VIGLVGSGKSSVAHELAKYIGATVIKGDD 85
Cdd:TIGR01313   3 LMGVAGSGKSTIASALAHRLGAKFIEGDD 31
YlqF_related_GTPase cd01849
Circularly permuted YlqF-related GTPases; These proteins are found in bacteria, eukaryotes, ...
 8-80 9.40e-03

Circularly permuted YlqF-related GTPases; These proteins are found in bacteria, eukaryotes, and archaea. They all exhibit a circular permutation of the GTPase signature motifs so that the order of the conserved G box motifs is G4-G5-G1-G2-G3, with G4 and G5 being permuted from the C-terminal region of proteins in the Ras superfamily to the N-terminus of YlqF-related GTPases.


Pssm-ID: 206746 [Multi-domain]  Cd Length: 146  Bit Score: 35.44  E-value: 9.40e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 818609379   8 LIEFIPLSIIKIImecKRKLTKKESTAQNAFMAKLDIKQRKTKEPVIVAVIGLVGSGKSSVAHELAKYIGATV 80
Cdd:cd01849   50 VAELSELYGTKTF---FISATNGQGILKLKAEITKQKLKLKYKKGIRVGVVGLPNVGKSSFINALLNKFKLKV 119
 
Name Accession Description Interval E-value
COG0645 COG0645
Predicted kinase, contains AAA domain [General function prediction only];
54-162 1.04e-19

Predicted kinase, contains AAA domain [General function prediction only];


Pssm-ID: 440410 [Multi-domain]  Cd Length: 164  Bit Score: 83.04  E-value: 1.04e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609379  54 IVAVIGLVGSGKSSVAHELAKYIGATVIKGDDIRIELRKQS----EKYKQARTIAENA----AVEIVKQGGNVILDSDFV 125
Cdd:COG0645    1 LILVCGLPGSGKSTLARALAERLGAVRLRSDVVRKRLFGAGlaplERSPEATARTYARllalARELLAAGRSVILDATFL 80

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 818609379 126 DEKKRASVREKARKAGVRLVFVRTHCDLDVMVGRVLT 162
Cdd:COG0645   81 RRAQREAFRALAEEAGAPFVLIWLDAPEEVLRERLEA 117
AAA_33 pfam13671
AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the ...
 55-177 5.55e-13

AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.


Pssm-ID: 463952 [Multi-domain]  Cd Length: 143  Bit Score: 64.25  E-value: 5.55e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609379   55 VAVIGLVGSGKSSVAHELAKYIGATVIKGDDIR----IELRKQSEKYKQARTIAENAAVEIV----KQGGNVILDSDFVD 126
Cdd:pfam13671   2 ILLVGLPGSGKSTLARRLLEELGAVRLSSDDERkrlfGEGRPSISYYTDATDRTYERLHELArialRAGRPVILDATNLR 81

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 818609379  127 EKKRASVREKARKAGVRLVFVRTHCDLDVMVGRVlTATYHNRVDDFFGGAE 177
Cdd:pfam13671  82 RDERARLLALAREYGVPVRIVVFEAPEEVLRERL-AARARAGGDPSDVPEE 131
COG4639 COG4639
Predicted kinase [General function prediction only];
51-155 1.77e-08

Predicted kinase [General function prediction only];


Pssm-ID: 443677 [Multi-domain]  Cd Length: 145  Bit Score: 51.75  E-value: 1.77e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609379  51 EPVIVAVIGLVGSGKSSVAHELAKyiGATVIKGDDIRIEL---RKQSEKYKQARTIAENAAVEIVKQGGNVILDSDFVDE 127
Cdd:COG4639    1 MLSLVVLIGLPGSGKSTFARRLFA--PTEVVSSDDIRALLggdENDQSAWGDVFQLAHEIARARLRAGRLTVVDATNLQR 78

                         90       100
                 ....*....|....*....|....*...
gi 818609379 128 KKRASVREKARKAGVRLVFVrthcDLDV 155
Cdd:COG4639   79 EARRRLLALARAYGALVVAV----VLDV 102
GntK cd02021
Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting ...
 54-166 9.45e-08

Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits.


Pssm-ID: 238979 [Multi-domain]  Cd Length: 150  Bit Score: 49.94  E-value: 9.45e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609379  54 IVAVIGLVGSGKSSVAHELAKYIGATVIKGDDirieLRKQSEKYKQAR--------------TIAENAAVEIVKQGGNVI 119
Cdd:cd02021    1 IIVVMGVSGSGKSTVGKALAERLGAPFIDGDD----LHPPANIAKMAAgiplndedrwpwlqALTDALLAKLASAGEGVV 76

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 818609379 120 LDSDFvdEKKRasVREKARK--AGVRLVFVRTHCDLDVMVGRVLTATYH 166
Cdd:cd02021   77 VACSA--LKRI--YRDILRGgaANPRVRFVHLDGPREVLAERLAARKGH 121
pseT PHA02530
polynucleotide kinase; Provisional
 54-159 9.18e-07

polynucleotide kinase; Provisional


Pssm-ID: 222856 [Multi-domain]  Cd Length: 300  Bit Score: 48.87  E-value: 9.18e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609379  54 IVAVIGLVGSGKSSVAHELA-KYIGATVIKGDDIRIEL---RKQSE-KYKQAR----TIAE-NAAVEIVKQGGNVILDSD 123
Cdd:PHA02530   4 IILTVGVPGSGKSTWAREFAaKNPKAVNVNRDDLRQSLfghGEWGEyKFTKEKedlvTKAQeAAALAALKSGKSVIISDT 83

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 818609379 124 FVDEKKRASVREKARKAGVRLVFVRTHCDLDVMVGR 159
Cdd:PHA02530  84 NLNPERRRKWKELAKELGAEFEEKVFDVPVEELVKR 119
CysC COG0529
Adenylylsulfate kinase or related kinase [Inorganic ion transport and metabolism]; ...
 41-155 1.10e-06

Adenylylsulfate kinase or related kinase [Inorganic ion transport and metabolism]; Adenylylsulfate kinase or related kinase is part of the Pathway/BioSystem: Cysteine biosynthesis


Pssm-ID: 440295 [Multi-domain]  Cd Length: 189  Bit Score: 47.78  E-value: 1.10e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609379  41 KLDIKQRKTKEPVIVAVIGLVGSGKSSVAHELAK-----YIGATVIKGDDIRIELRK-----QSEKYKQARTIAEnAAVE 110
Cdd:COG0529    5 REERAALKGQKGFVVWFTGLSGSGKSTLANALERrlferGRHVYLLDGDNVRHGLNKdlgfsKEDRDENIRRIGE-VAKL 83

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 818609379 111 IVKQGGNVILD--SDFVDEkkRASVREKARKAGVRLVFVRthCDLDV 155
Cdd:COG0529   84 LADAGLIVLVAfiSPYRAD--REEARELIGEGEFIEVYVD--TPLEV 126
APS_kinase pfam01583
Adenylylsulphate kinase; Enzyme that catalyzes the phosphorylation of adenylylsulphate to 3 ...
 52-159 8.84e-06

Adenylylsulphate kinase; Enzyme that catalyzes the phosphorylation of adenylylsulphate to 3'-phosphoadenylylsulfate. This domain contains an ATP binding P-loop motif.


Pssm-ID: 396247 [Multi-domain]  Cd Length: 154  Bit Score: 44.62  E-value: 8.84e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609379   52 PVIVAVIGLVGSGKSSVAHELAKY-----IGATVIKGDDIRIELRK---QSEKYKQA--RTIAEnAAVEIVKQGGNVI-- 119
Cdd:pfam01583   2 GCTIWLTGLSGAGKSTIANALERKlfeqgRSVYVLDGDNVRHGLNKdlgFSEEDRTEniRRIGE-VAKLFADAGLIVIta 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 818609379  120 LDSDFVDEkkRASVREKARKAGVRLVFVRthCDLDVMVGR 159
Cdd:pfam01583  81 FISPYRED--REQARELHEEGKFIEVFVD--TPLEVCEQR 116
CMPK cd02020
Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine ...
 54-122 1.03e-05

Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor.


Pssm-ID: 238978 [Multi-domain]  Cd Length: 147  Bit Score: 44.01  E-value: 1.03e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 818609379  54 IVAVIGLVGSGKSSVAHELAKYIGATVIKGDDIRIElrkqsEKYKQARTIAENAAV--EIVK------QGGNVILDS 122
Cdd:cd02020    1 IIAIDGPAGSGKSTVAKLLAKKLGLPYLDTGGIRTE-----EVGKLASEVAAIPEVrkALDErqrelaKKPGIVLEG 72
GntK COG3265
Gluconate kinase [Carbohydrate transport and metabolism]; Gluconate kinase is part of the ...
 52-85 9.10e-05

Gluconate kinase [Carbohydrate transport and metabolism]; Gluconate kinase is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 442496 [Multi-domain]  Cd Length: 164  Bit Score: 41.65  E-value: 9.10e-05
                         10        20        30
                 ....*....|....*....|....*....|....
gi 818609379  52 PVIVAVIGLVGSGKSSVAHELAKYIGATVIKGDD 85
Cdd:COG3265    1 PMVIVVMGVSGSGKSTVGQALAERLGWPFIDGDD 34
Zeta_toxin pfam06414
Zeta toxin; This family consists of several bacterial zeta toxin proteins. Zeta toxin is ...
 42-178 3.04e-04

Zeta toxin; This family consists of several bacterial zeta toxin proteins. Zeta toxin is thought to be part of a postregulational killing system in bacteria. It relies on antitoxin/toxin systems that secure stable inheritance of low and medium copy number plasmids during cell division and kill cells that have lost the plasmid.


Pssm-ID: 428926  Cd Length: 192  Bit Score: 40.42  E-value: 3.04e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609379   42 LDIKQRKTKEPVIVAVIGLVGSGKSSVAHELAKYIGAT----VIKGDDIRIELRKQSEKYKQ------------ARTIAE 105
Cdd:pfam06414   1 LDDKTTSQERPKAILLGGQPGAGKTELARALLDELGRQgnvvRIDPDDFRELHPHYRELQAAdpktaseytqpdASRWVE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609379  106 NAAVEIVKQGGNVILDSDFVDEKKRASVREKARKAG--VRLVFVRTHCDL-----------DVMVGRVLTATYHNRVddF 172
Cdd:pfam06414  81 KLLQHAIENGYNIILEGTLRSPDVAKKIARALKAAGyrVEVAAVAAPPELswlgvldryeeEVAEGRYVPKEHHDEA--F 158


                  ....*.
gi 818609379  173 FGGAES 178
Cdd:pfam06414 159 NGLRES 164
Udk COG0572
Uridine kinase [Nucleotide transport and metabolism]; Uridine kinase is part of the Pathway ...
 47-85 5.58e-04

Uridine kinase [Nucleotide transport and metabolism]; Uridine kinase is part of the Pathway/BioSystem: Pyrimidine salvage


Pssm-ID: 440337 [Multi-domain]  Cd Length: 206  Bit Score: 39.82  E-value: 5.58e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 818609379  47 RKTKEPVIVAVIGLVGSGKSSVAHELAKYIG---ATVIKGDD 85
Cdd:COG0572    2 ARSGKPRIIGIAGPSGSGKTTFARRLAEQLGadkVVVISLDD 43
PRK04220 PRK04220
2-phosphoglycerate kinase; Provisional
 47-92 6.09e-04

2-phosphoglycerate kinase; Provisional


Pssm-ID: 179793 [Multi-domain]  Cd Length: 301  Bit Score: 40.33  E-value: 6.09e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 818609379  47 RKTKEPVIVAVIGLVGSGKSSVAHELAKYIG-ATVIKGDDIRIELRK 92
Cdd:PRK04220  87 RKSKEPIIILIGGASGVGTSTIAFELASRLGiRSVIGTDSIREVMRK 133
APSK cd02027
Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5 ...
 59-155 6.69e-04

Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form important for the assimilation of inorganic sulfate.


Pssm-ID: 238985 [Multi-domain]  Cd Length: 149  Bit Score: 39.00  E-value: 6.69e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609379  59 GLVGSGKSSVAHELAKY-----IGATVIKGDDIRIELRKQ-----SEKYKQARTIAENAAvEIVKQGGNVIldSDFV--D 126
Cdd:cd02027    6 GLSGSGKSTIARALEEKlfqrgRPVYVLDGDNVRHGLNKDlgfsrEDREENIRRIAEVAK-LLADAGLIVI--AAFIspY 82

                         90       100
                 ....*....|....*....|....*....
gi 818609379 127 EKKRASVREKARKAGVRLVFVRthCDLDV 155
Cdd:cd02027   83 REDREAARKIIGGGDFLEVFVD--TPLEV 109
therm_gnt_kin TIGR01313
carbohydrate kinase, thermoresistant glucokinase family; This model represents a subfamily of ...
 57-85 6.73e-04

carbohydrate kinase, thermoresistant glucokinase family; This model represents a subfamily of proteins that includes thermoresistant and thermosensitve isozymes of gluconate kinase (gluconokinase) in E. coli and other related proteins; members of this family are often named by similarity to the thermostable isozyme. These proteins show homology to shikimate kinases and adenylate kinases but not to gluconate kinases from the FGGY family of carbohydrate kinases.


Pssm-ID: 273551  Cd Length: 163  Bit Score: 39.31  E-value: 6.73e-04
                          10        20
                  ....*....|....*....|....*....
gi 818609379   57 VIGLVGSGKSSVAHELAKYIGATVIKGDD 85
Cdd:TIGR01313   3 LMGVAGSGKSTIASALAHRLGAKFIEGDD 31
Pgk2 COG2074
2-phosphoglycerate kinase/Mevalonate-3-phosphate 5-kinase [Carbohydrate transport and ...
 47-92 8.07e-04

2-phosphoglycerate kinase/Mevalonate-3-phosphate 5-kinase [Carbohydrate transport and metabolism, Lipid transport and metabolism];


Pssm-ID: 441677  Cd Length: 207  Bit Score: 39.55  E-value: 8.07e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 818609379  47 RKTKEPVIVAVIGLVGSGKSSVAHELAKYIGAT-VIKGDDIRIELRK 92
Cdd:COG2074    1 RRMKRPRIILIGGASGVGKSTIAAELARRLGIPrVISTDSIREVMRP 47
PRK04182 PRK04182
cytidylate kinase; Provisional
 53-122 1.97e-03

cytidylate kinase; Provisional


Pssm-ID: 235244 [Multi-domain]  Cd Length: 180  Bit Score: 37.86  E-value: 1.97e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609379  53 VIVAVIGLVGSGKSSVAHELAKYIGATVIKGDDIRIELRKQ-----SEKYKQARTIAE------NAAVEIVKQGGNVILD 121
Cdd:PRK04182   1 MIITISGPPGSGKTTVARLLAEKLGLKHVSAGEIFRELAKErgmslEEFNKYAEEDPEidkeidRRQLEIAEKEDNVVLE 80


                 .
gi 818609379 122 S 122
Cdd:PRK04182  81 G 81
PRK12337 PRK12337
2-phosphoglycerate kinase; Provisional
 47-91 6.29e-03

2-phosphoglycerate kinase; Provisional


Pssm-ID: 183452 [Multi-domain]  Cd Length: 475  Bit Score: 37.45  E-value: 6.29e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 818609379  47 RKTKEPVIVAVIGLVGSGKSSVAHELAKYIGAT-VIKGDDIRIELR 91
Cdd:PRK12337 250 RRPPRPLHVLIGGVSGVGKSVLASALAYRLGITrIVSTDAVREVLR 295
YlqF_related_GTPase cd01849
Circularly permuted YlqF-related GTPases; These proteins are found in bacteria, eukaryotes, ...
 8-80 9.40e-03

Circularly permuted YlqF-related GTPases; These proteins are found in bacteria, eukaryotes, and archaea. They all exhibit a circular permutation of the GTPase signature motifs so that the order of the conserved G box motifs is G4-G5-G1-G2-G3, with G4 and G5 being permuted from the C-terminal region of proteins in the Ras superfamily to the N-terminus of YlqF-related GTPases.


Pssm-ID: 206746 [Multi-domain]  Cd Length: 146  Bit Score: 35.44  E-value: 9.40e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 818609379   8 LIEFIPLSIIKIImecKRKLTKKESTAQNAFMAKLDIKQRKTKEPVIVAVIGLVGSGKSSVAHELAKYIGATV 80
Cdd:cd01849   50 VAELSELYGTKTF---FISATNGQGILKLKAEITKQKLKLKYKKGIRVGVVGLPNVGKSSFINALLNKFKLKV 119
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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