|
Name |
Accession |
Description |
Interval |
E-value |
| PRK08247 |
PRK08247 |
methionine biosynthesis PLP-dependent protein; |
1-366 |
0e+00 |
|
methionine biosynthesis PLP-dependent protein;
Pssm-ID: 181320 [Multi-domain] Cd Length: 366 Bit Score: 801.23 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 1 MSQHVETKLAQIGNRSDEVTGTVSAPIYLSTAYRHRGIGESTGFDYVRTKNPTRQLVEDAIANLENGARGLAFSSGMAAI 80
Cdd:PRK08247 1 QMSTIETKLAQIGNRSDERTGTVNPPVYFSTAYRHEGIGESTGFDYSRTGNPTRGVLEQAIADLEGGDQGFACSSGMAAI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 81 QTIMALFKSGDELIVSSDLYGGTYRLFENEWKKYGLTFHYDDFSDEDCLRSKITPNTKAVFVETPTNPLMQEADIEHIAR 160
Cdd:PRK08247 81 QLVMSLFRSGDELIVSSDLYGGTYRLFEEHWKKWNVRFVYVNTASLKAIEQAITPNTKAIFIETPTNPLMQETDIAAIAK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 161 ITKEHGLLLIVDNTFYTPVLQRPLELGADIVIHSATKYLGGHNDLLAGLVVVKDERLGEEMFQHQNAIGAVLPPFDSWLL 240
Cdd:PRK08247 161 IAKKHGLLLIVDNTFYTPVLQRPLEEGADIVIHSATKYLGGHNDVLAGLVVAKGQELCERLAYYQNAAGAVLSPFDSWLL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 241 MRGMKTLSLRMRQHQANAQELAAFLEEQEEISDVLYPGKGGMLSFRLQKEEWVNPFLKALKTICFAESLGGVESFITYPA 320
Cdd:PRK08247 241 IRGMKTLALRMRQHEENAKAIAAFLNEQPGVTDVLYPGRGGMLSFRLQDEEWVNPFLKSLKLITFAESLGGVESFITYPA 320
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 906392210 321 TQTHMDIPEEIRIANGVCNRLLRFSVGIEHAEDLKEDLKQALCQVK 366
Cdd:PRK08247 321 TQTHADIPEEIRIANGVCNRLLRFSVGIENVEDLIADLKQAFKQVK 366
|
|
| Cys_Met_Meta_PP |
pfam01053 |
Cys/Met metabolism PLP-dependent enzyme; This family includes enzymes involved in cysteine and ... |
6-363 |
0e+00 |
|
Cys/Met metabolism PLP-dependent enzyme; This family includes enzymes involved in cysteine and methionine metabolism. The following are members: Cystathionine gamma-lyase, Cystathionine gamma-synthase, Cystathionine beta-lyase, Methionine gamma-lyase, OAH/OAS sulfhydrylase, O-succinylhomoserine sulfhydrylase All of these members participate is slightly different reactions. All these enzymes use PLP (pyridoxal-5'-phosphate) as a cofactor.
Pssm-ID: 395837 [Multi-domain] Cd Length: 376 Bit Score: 571.10 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 6 ETKLAQIGNRSDEVTGTVSAPIYLSTAYRHRGIGESTGFDYVRTKNPTRQLVEDAIANLENGARGLAFSSGMAAI-QTIM 84
Cdd:pfam01053 1 DTLAVHAGQRPDPQTGAVSVPIYLTSTYVFDFAGEEGGYDYSRSGNPTRDVLEERIAALEGGAAALAFSSGMAAItAAIL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 85 ALFKSGDELIVSSDLYGGTYRLFENEWKKYGLTFHYDDFSDEDCLRSKITPNTKAVFVETPTNPLMQEADIEHIARITKE 164
Cdd:pfam01053 81 ALLKAGDHIVATDDLYGGTYRLFNKVLPRFGIEVTFVDTSDPEDLEAAIKPNTKAVYLETPTNPLLKVVDIEAIAKLAKK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 165 HGLLLIVDNTFYTPVLQRPLELGADIVIHSATKYLGGHNDLLAGLVVVKDERLGEEMFQHQNAIGAVLPPFDSWLLMRGM 244
Cdd:pfam01053 161 HGILVVVDNTFASPYLQRPLDLGADIVVHSATKYIGGHSDVVGGVIVVNGEELGKELYFLQNATGAVLSPFDAWLLLRGL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 245 KTLSLRMRQHQANAQELAAFLEEQEEISDVLYPG----------------KGGMLSFRLQKE-EWVNPFLKALKTICFAE 307
Cdd:pfam01053 241 KTLGLRMEQHQENAQKVAEFLESHPKVEKVYYPGlpshpghelakrqmkgFGGMLSFELKGGlEAAKKFLDNLKLFSLAV 320
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 906392210 308 SLGGVESFITYPATQTHMDIPEEIRIANGVCNRLLRFSVGIEHAEDLKEDLKQALC 363
Cdd:pfam01053 321 SLGGVESLISHPATMTHASIPPEEREAAGITDDLIRLSVGIEDVDDLIADLKQALE 376
|
|
| MetC |
COG0626 |
Cystathionine beta-lyase/cystathionine gamma-synthase [Amino acid transport and metabolism]; ... |
3-362 |
0e+00 |
|
Cystathionine beta-lyase/cystathionine gamma-synthase [Amino acid transport and metabolism]; Cystathionine beta-lyase/cystathionine gamma-synthase is part of the Pathway/BioSystem: Methionine biosynthesis
Pssm-ID: 440391 [Multi-domain] Cd Length: 389 Bit Score: 522.69 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 3 QHVETKLAQIGNRSDEVTGTVSAPIYLSTAYRH--------RGIGESTGFDYVRTKNPTRQLVEDAIANLENGARGLAFS 74
Cdd:COG0626 1 MGPATRAVHAGRDPDPQTGAVSPPIYLTSTFVFpsaealaaRFAGEEGGYIYSRYGNPTRRALEEALAALEGGEAALAFA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 75 SGMAAIQT-IMALFKSGDELIVSSDLYGGTYRLFENEWKKYGLTFHYDDFSDEDCLRSKITPNTKAVFVETPTNPLMQEA 153
Cdd:COG0626 81 SGMAAISAvLLALLKAGDHVVASDDLYGGTRRLLDKVLARFGIEVTFVDPTDLAAVEAAIRPNTKLVFLETPSNPTLEVV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 154 DIEHIARITKEHGLLLIVDNTFYTPVLQRPLELGADIVIHSATKYLGGHNDLLAGLVVVKDERLGEEMFQHQNAIGAVLP 233
Cdd:COG0626 161 DIAAIAAIAHAAGALLVVDNTFATPLLQRPLELGADIVVHSATKYLGGHSDVLGGAVVGRDEELAERLRFLQNALGAVLS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 234 PFDSWLLMRGMKTLSLRMRQHQANAQELAAFLEEQEEISDVLYPG----------K------GGMLSFRLQK-EEWVNPF 296
Cdd:COG0626 241 PFDAWLLLRGLKTLALRMERHCENALAVAEWLEAHPAVARVYYPGlpshpghelaKrqmsgfGGMLSFELKGgREAARRF 320
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 906392210 297 LKALKTICFAESLGGVESFITYPATQTHMDIPEEIRIANGVCNRLLRFSVGIEHAEDLKEDLKQAL 362
Cdd:COG0626 321 LDALKLFTLAVSLGGVESLITHPATMTHRSLPPEERAALGITDGLVRLSVGLEDVDDLIADLEQAL 386
|
|
| PRK07269 |
PRK07269 |
cystathionine gamma-synthase; Reviewed |
1-362 |
1.54e-155 |
|
cystathionine gamma-synthase; Reviewed
Pssm-ID: 235983 Cd Length: 364 Bit Score: 441.95 E-value: 1.54e-155
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 1 MSQHVETKLAQIGNRSDEVTGTVSAPIYLSTAYRHRGIGESTGFDYVRTKNPTRQLVEDAIANLENGARGLAFSSGMAAI 80
Cdd:PRK07269 3 KDLHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGQSTGFDYTRTKNPTRAKLEETLAAIESADYALATSSGMSAI 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 81 QTIMALFKSGDELIVSSDLYGGTYRLFeNEWKKYGlTFHYDDFSDEDCLRSKITPNTKAVFVETPTNPLMQEADIEHIAR 160
Cdd:PRK07269 83 VLAFSVFPVGSKVVAVRDLYGGSFRWF-NQQEKEG-RFHFTYANTEEELIAAIEEDTDIVYIETPTNPLMVEFDIEKVAK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 161 ITKEHGLLLIVDNTFYTPVLQRPLELGADIVIHSATKYLGGHNDLLAGLVVVKDERLGEEMFQHQNAIGAVLPPFDSWLL 240
Cdd:PRK07269 161 LAHAKGAKVIVDNTFYSPIYQRPIELGADIVLHSATKYLSGHNDVLAGVVVTNDLELYEKLFYNLNTTGAVLSPFDSYLL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 241 MRGMKTLSLRMRQHQANAQELAAFLEEQEEISDVLYPGKGGMLSFRLQKEEWVNPFLKALKTICFAESLGGVESFITYPA 320
Cdd:PRK07269 241 MRGLKTLSLRMERSTANAQEVVAFLKKSPAVKEVLYTGKGGMISFKVADETRIPHILNSLKVFTFAESLGGVESLITYPT 320
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 906392210 321 TQTHMDIPEEIRIANGVCNRLLRFSVGIEHAEDLKEDLKQAL 362
Cdd:PRK07269 321 TQTHADIPAEVRHSYGLTDDLLRLSIGIEDARDLIADLKQAL 362
|
|
| CGS_like |
cd00614 |
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed ... |
21-362 |
3.98e-155 |
|
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of antimicrobials and herbicides. This subgroup also includes cystathionine gamma-lyases (CGL), O-acetylhomoserine sulfhydrylases and O-acetylhomoserine thiol lyases. CGL's are very similar to CGS's. Members of this group are widely distributed among all three forms of life.
Pssm-ID: 99738 [Multi-domain] Cd Length: 369 Bit Score: 440.87 E-value: 3.98e-155
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 21 GTVSAPIYLSTAYRHRGIGEST--------GFDYVRTKNPTRQLVEDAIANLENGARGLAFSSGMAAIQT-IMALFKSGD 91
Cdd:cd00614 1 GAVAPPIYQTSTFVFPSPAEAAdlfalregGYIYSRIGNPTVDALEKKLAALEGGEAALAFSSGMAAISTvLLALLKAGD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 92 ELIVSSDLYGGTYRLFENEWKKYGLTFHYDDFSDEDCLRSKITPNTKAVFVETPTNPLMQEADIEHIARITKEHGLLLIV 171
Cdd:cd00614 81 HVVASDDLYGGTYRLFERLLPKLGIEVTFVDPDDPEALEAAIKPETKLVYVESPTNPTLKVVDIEAIAELAHEHGALLVV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 172 DNTFYTPVLQRPLELGADIVIHSATKYLGGHNDLLAGLVVVKDERLGEEMFQHQNAIGAVLPPFDSWLLMRGMKTLSLRM 251
Cdd:cd00614 161 DNTFATPYLQRPLELGADIVVHSATKYIGGHSDVIAGVVVGSGEALIQRLRFLRLALGTILSPFDAWLLLRGLKTLPLRM 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 252 RQHQANAQELAAFLEEQEEISDVLYP----------------GKGGMLSFRLQK-EEWVNPFLKALKTICFAESLGGVES 314
Cdd:cd00614 241 ERHSENALKVAEFLEKHPKVERVYYPglpshpqhelakkqmsGYGGVFSFELKGgLEAAKKFLNALKLFSLAVSLGGVES 320
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 906392210 315 FITYPATQTHMDIPEEIRIANGVCNRLLRFSVGIEHAEDLKEDLKQAL 362
Cdd:cd00614 321 LVEHPASMTHSQLPPEERAAAGITPGLVRLSVGIEDVEDLIADLEQAL 368
|
|
| PRK07671 |
PRK07671 |
bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase; |
6-362 |
2.27e-153 |
|
bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase;
Pssm-ID: 181076 [Multi-domain] Cd Length: 377 Bit Score: 436.85 E-value: 2.27e-153
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 6 ETKLAQIGNRSDEVTGTVSAPIYLSTAYRHRGIGESTGFDYVRTKNPTRQLVEDAIANLENGARGLAFSSGMAAIQTIMA 85
Cdd:PRK07671 4 KTKLIHGGIIGDPSTGAVSVPIYQVSTYKQEAVGKHQGYEYSRTGNPTRAALEELIAVLEGGHAGFAFGSGMAAITAVMM 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 86 LFKSGDELIVSSDLYGGTYRLFENEWKKYGLTFHYDDFSDEDCLRSKITPNTKAVFVETPTNPLMQEADIEHIARITKEH 165
Cdd:PRK07671 84 LFSSGDHVILTDDVYGGTYRVMTKVLNRFGIEHTFVDTSNLEEVEEAIRPNTKAIYVETPTNPLLKITDIKKISTIAKEK 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 166 GLLLIVDNTFYTPVLQRPLELGADIVIHSATKYLGGHNDLLAGLVVVKDERLGEEMFQHQNAIGAVLPPFDSWLLMRGMK 245
Cdd:PRK07671 164 GLLTIVDNTFMTPYWQSPISLGADIVLHSATKYLGGHSDVVAGLVVVNSPELAEDLHFVQNSTGGILGPQDSWLLLRGLK 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 246 TLSLRMRQHQANAQELAAFLEEQEEISDVLYPGK----------------GGMLSFRLQKEEWVNPFLKALKTICFAESL 309
Cdd:PRK07671 244 TLGIRMEEHETNSRAIAEFLNNHPAVNKVYYPGLpshpnhelakeqangfGGMISFDVGSEETANKVLERLQYFTLAESL 323
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 906392210 310 GGVESFITYPATQTHMDIPEEIRIANGVCNRLLRFSVGIEHAEDLKEDLKQAL 362
Cdd:PRK07671 324 GAVESLISIPSQMTHASIPADRRKELGITDGLIRISVGIEDGEDLIEDLAQAL 376
|
|
| PRK07811 |
PRK07811 |
cystathionine gamma-synthase; Provisional |
1-364 |
3.00e-147 |
|
cystathionine gamma-synthase; Provisional
Pssm-ID: 236104 [Multi-domain] Cd Length: 388 Bit Score: 421.75 E-value: 3.00e-147
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 1 MSQHVETKLAQIGNRSDEVTGTVSAPIYLSTAYRHRGIGE-STGFDYVRTKNPTRQLVEDAIANLENGARGLAFSSGMAA 79
Cdd:PRK07811 9 ANQGFATRAIHAGYEPDPATGAVNPPIYASSTFAQDGVGGlRGGYEYARTGNPTRTALEEQLAALEGGAYGRAFSSGMAA 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 80 IQTIM-ALFKSGDELIVSSDLYGGTYRLFENEWKKYGLTFHYDDFSDEDCLRSKITPNTKAVFVETPTNPLMQEADIEHI 158
Cdd:PRK07811 89 TDCLLrAVLRPGDHIVIPNDAYGGTFRLIDKVFTRWGVEYTPVDLSDLDAVRAAITPRTKLIWVETPTNPLLSITDIAAL 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 159 ARITKEHGLLLIVDNTFYTPVLQRPLELGADIVIHSATKYLGGHNDLLAGLVVVKDERLGEEMFQHQNAIGAVLPPFDSW 238
Cdd:PRK07811 169 AELAHDAGAKVVVDNTFASPYLQQPLALGADVVVHSTTKYIGGHSDVVGGALVTNDEELDEAFAFLQNGAGAVPGPFDAY 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 239 LLMRGMKTLSLRMRQHQANAQELAAFLEEQEEISDVLYPGK----------------GGMLSFRLQK-EEWVNPFLKALK 301
Cdd:PRK07811 249 LTLRGLKTLAVRMDRHSENAEAVAEFLAGHPEVSTVLYPGLpshpghevaarqmrgfGGMVSVRLAGgEEAARDFCARTK 328
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 302 TICFAESLGGVESFITYPATQTH-------MDIPEEiriangvcnrLLRFSVGIEHAEDLKEDLKQALCQ 364
Cdd:PRK07811 329 VFTLAESLGGVESLIEHPSAMTHastagsqLEVPDD----------LVRLSVGIEDVADLLADLEQALGQ 388
|
|
| PRK06176 |
PRK06176 |
cystathionine gamma-synthase; |
4-362 |
7.19e-140 |
|
cystathionine gamma-synthase;
Pssm-ID: 180443 [Multi-domain] Cd Length: 380 Bit Score: 402.74 E-value: 7.19e-140
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 4 HVETKLAQIGNRSDEVTGTVSAPIYLSTAYRHRGIGESTGFDYVRTKNPTRQLVEDAIANLENGARGLAFSSGMAAIQTI 83
Cdd:PRK06176 2 RMQTKLIHGGISEDTTTGAVSVPIYQTSTYRQDAIGRPKGYEYSRSGNPTRFALEELIADLEGGVKGFAFASGLAGIHAV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 84 MALFKSGDELIVSSDLYGGTYRLFENEWKKYGLTFHYDDFSDEDCLRSKITPNTKAVFVETPTNPLMQEADIEHIARITK 163
Cdd:PRK06176 82 FSLFQSGDHVLLGDDVYGGTFRLFDKVLVKNGLSCTIIDTSDLSQIKKAIKPNTKALYLETPSNPLLKITDLAQCASVAK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 164 EHGLLLIVDNTFYTPVLQRPLELGADIVIHSATKYLGGHNDLLAGLVVVKDERLGEEMFQHQNAIGAVLPPFDSWLLMRG 243
Cdd:PRK06176 162 DHGLLTIVDNTFATPYYQNPLLLGADIVVHSGTKYLGGHSDVVAGLVTTNNEALAQEIAFFQNAIGGVLGPQDSWLLQRG 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 244 MKTLSLRMRQHQANAQELAAFLEEQEEISDVLYPGK----------------GGMLSFRLQKEEWVNPFLKALKTICFAE 307
Cdd:PRK06176 242 IKTLGLRMEAHQKNALCVAEFLEKHPKVEKVYYPGLpthpnhelakkqmrgfSGMLSFTLKNDSEAVAFVESLKLFILGE 321
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 906392210 308 SLGGVESFITYPATQTHMDIPEEIRIANGVCNRLLRFSVGIEHAEDLKEDLKQAL 362
Cdd:PRK06176 322 SLGGVESLVGIPAFMTHACIPKEQREAAGIRDGLVRLSVGIEHEQDLLEDLEQAF 376
|
|
| PRK08064 |
PRK08064 |
cystathionine beta-lyase MetC; |
1-371 |
9.36e-139 |
|
cystathionine beta-lyase MetC;
Pssm-ID: 236146 [Multi-domain] Cd Length: 390 Bit Score: 400.30 E-value: 9.36e-139
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 1 MSQH--VETKLAQIGNRSDEVTGTVSAPIYLSTAYRHRGIGESTGFDYVRTKNPTRQLVEDAIANLENGARGLAFSSGMA 78
Cdd:PRK08064 1 MAMSysIDTLLLHNQYKHDKQTGAVNVPIYHASTFHQFDFDTFGKYDYSRSGNPTREALEDIIAELEGGTKGFAFASGMA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 79 AIQTIMALFKSGDELIVSSDLYGGTYRLFENEWKKYGLTFHYDDFSDEDCLRSKITPNTKAVFVETPTNPLMQEADIEHI 158
Cdd:PRK08064 81 AISTAFLLLSKGDHVLISEDVYGGTYRMITEVLSRFGIEHTFVDMTNLEEVAQNIKPNTKLFYVETPSNPLLKVTDIRGV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 159 ARITKEHGLLLIVDNTFYTPVLQRPLELGADIVIHSATKYLGGHNDLLAGLVVVKDERLGEEMFQHQNAIGAVLPPFDSW 238
Cdd:PRK08064 161 VKLAKAIGCLTFVDNTFLTPLLQKPLDLGADVVLHSATKFLAGHSDVLAGLAVVKDEELAQKLYFLQNSFGAVLGVQDCW 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 239 LLMRGMKTLSLRMRQHQANAQELAAFLEEQEEISDVLYPG----------------KGGMLSFRLQKEEWVNPFLKALKT 302
Cdd:PRK08064 241 LVLRGLKTLHVRLEHSSETANKIALYLQEHPKVQNVYYPGlqthlgfdiqqsqatsAGAVLSFTLQSEEAVRQFVSHVKL 320
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 906392210 303 ICFAESLGGVESFITYPATQTHMDIPEEIRIANGVCNRLLRFSVGIEHAEDLKEDLKQALCQVKEGAVS 371
Cdd:PRK08064 321 PVFAVSLGAVESILSYPAKMSHAAMPKEERDERGITDGLLRLSVGLENVDDLIADFEQALSYVEEPVNA 389
|
|
| PRK06767 |
PRK06767 |
methionine gamma-lyase; Provisional |
3-365 |
1.30e-121 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 180685 [Multi-domain] Cd Length: 386 Bit Score: 356.46 E-value: 1.30e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 3 QHVETKLAQIGNRSDEVTGTVSAPIYLSTAY--------RHRGIGESTGFDYVRTKNPTRQLVEDAIANLENGARGLAFS 74
Cdd:PRK06767 4 KHMETALIHHGYTSEEHKGSLTPPLFQTSTFtfetaqqgEASFAGVDPSYIYSRLGNPTVKLFEERMAVLEGGEEALAFG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 75 SGMAAIQ-TIMALFKSGDELIVSSDLYGGTYRLFENEWKKYGLTFHYDDFSDEDCLRSKITPNTKAVFVETPTNPLMQEA 153
Cdd:PRK06767 84 SGMAAISaTLIGFLKAGDHIICSNGLYGCTYGFLEVLEEKFMITHSFCDMETEADIENKIRPNTKLIFVETPINPTMKLI 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 154 DIEHIARITKEHGLLLIVDNTFYTPVLQRPLELGADIVIHSATKYLGGHNDLLAGLVVVKDERLGEEMFQHQNAIGAVLP 233
Cdd:PRK06767 164 DLKQVIRVAKRNGLLVIVDNTFCSPYLQRPLELGCDAVVHSATKYIGGHGDVVAGVTICKTRALAEKIRPMRKDIGGIMA 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 234 PFDSWLLMRGMKTLSLRMRQHQANAQELAAFLEEQEEISDVLYPG----------KGGMLSFRLQ--KEEwVNPFLKALK 301
Cdd:PRK06767 244 PFDAWLLLRGLKTLAVRMDRHCDNAEKIVSFLKNHDAVEGVWYPEgelasrqmkrGGGVISFSIKggKEE-TQAFINDLH 322
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 906392210 302 TICFAESLGGVESFITYPATQTHMDIPEEIRIANGVCNRLLRFSVGIEHAEDLKEDLKQALCQV 365
Cdd:PRK06767 323 FITIAVSLGDTETLIQHPATMTHAAIPAELRQEMGIYDNLIRLSVGLESWEDIVSDLEQALKKI 386
|
|
| MET17 |
COG2873 |
O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent [Amino acid ... |
2-362 |
5.75e-118 |
|
O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent [Amino acid transport and metabolism]; O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent is part of the Pathway/BioSystem: Methionine biosynthesis
Pssm-ID: 442120 [Multi-domain] Cd Length: 428 Bit Score: 348.56 E-value: 5.75e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 2 SQHVETKLAQIGNRSDEVTGTVSAPIYLSTAYRHRGI--------GESTGFDYVRTKNPTRQLVEDAIANLENGARGLAF 73
Cdd:COG2873 5 KYGFETLALHAGQEPDPTTGARAVPIYQTTSYVFDDAehaadlfaLKEPGNIYTRIMNPTTDVLEKRIAALEGGVAALAT 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 74 SSGMAAI-QTIMALFKSGDELIVSSDLYGGTYRLFENEWKKYGLTFHYDDFSDEDCLRSKITPNTKAVFVETPTNPLMQE 152
Cdd:COG2873 85 ASGQAAItLAILNLAEAGDHIVASSSLYGGTYNLFAHTLPRLGIEVRFVDPDDPEAFEAAIDPNTKAIFGETIGNPALDV 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 153 ADIEHIARITKEHGLLLIVDNTFYTPVLQRPLELGADIVIHSATKYLGGHNDLLAGLVVvkD------------------ 214
Cdd:COG2873 165 LDIEAIAEIAHEHGVPLIVDNTFATPYLCRPIEHGADIVVHSATKYIGGHGTSIGGVIV--Dggnfdwaangkfpeltep 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 215 ----------ERLGEEMF------QHQNAIGAVLPPFDSWLLMRGMKTLSLRMRQHQANAQELAAFLEEQEEISDVLYP- 277
Cdd:COG2873 243 dpsyhglvytEAFGNAAFitkarvQLLRDLGAALSPFNAFLLLQGLETLSLRMERHVENALKVAEFLEAHPKVAWVNYPg 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 278 ----------------GKGGMLSFRLQK-EEWVNPFLKALKTICFAESLGGVESFITYPATQTHMDIPEEIRIANGVCNR 340
Cdd:COG2873 323 lpshpyhelaqkylpkGAGGVLTFGLKGgREAGKKFIDSLKLFSHLANIGDAKSLVIHPASTTHSQLSEEEQAAAGVTPD 402
|
410 420
....*....|....*....|..
gi 906392210 341 LLRFSVGIEHAEDLKEDLKQAL 362
Cdd:COG2873 403 LIRLSVGIEDIDDIIADLDQAL 424
|
|
| cysta_beta_ly_E |
TIGR01329 |
cystathionine beta-lyase, eukaryotic; This model represents cystathionine beta-lyase ... |
5-364 |
1.11e-113 |
|
cystathionine beta-lyase, eukaryotic; This model represents cystathionine beta-lyase (alternate name: beta-cystathionase), one of several pyridoxal-dependent enzymes of cysteine, methionine, and homocysteine metabolism. This enzyme is involved in the biosynthesis of Met from Cys.
Pssm-ID: 273557 [Multi-domain] Cd Length: 378 Bit Score: 336.03 E-value: 1.11e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 5 VETKLAQIGNRSDEVTGTvSAPIYLSTAYRHRGIGESTGFDYVRTKNPTRQLVEDAIANLENGARGLAFSSGMAAIQTIM 84
Cdd:TIGR01329 1 LSTLLVNTDNKNDPYDAS-SMPIYQTATFKQPLAIENGPYDYTRSGNPTRTALESLLAKLDKADRAFAFSSGMAALDVIT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 85 ALFKSGDELIVSSDLYGGTYRLFENEWKKYGLTFHYDDFSDEDCLRSKITPNTKAVFVETPTNPLMQEADIEHIARITKE 164
Cdd:TIGR01329 80 RLLNNGDEIIAGDDLYGGTDRLLTQVVPRSGVVVVHVDTTDLDKVKAALGPKTKLVLLESPTNPLQKIVDIRKISEMAHA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 165 HGLLLIVDNTFYTPVLQRPLELGADIVIHSATKYLGGHNDLLAGLVVVKDERLGEEMFQHQNAIGAVLPPFDSWLLMRGM 244
Cdd:TIGR01329 160 QNALVVVDNTMMSPLLCNPLELGADIVYHSATKFLAGHSDVMAGVLAVKGEEIAKKVYFLQNSTGSGLAPFDCWLLLRGI 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 245 KTLSLRMRQHQANAQELAAFLEEQEEISDVLYP----------------GKGGMLSFRLQKEEWVNPFLKALKTICFAES 308
Cdd:TIGR01329 240 KTLAIRIEKQQENARAIAMFLSTHPRVKKVRYAglpshpgfhlhfsqakGAGSVLSFETGSVALSKRLVEATKLFSITVS 319
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 906392210 309 LGGVESFITYPATQTHMDIPEEIRIANGVCNRLLRFSVGIEHAEDLKEDLKQALCQ 364
Cdd:TIGR01329 320 FGSVNSLISMPCFMSHASIPAEVREERGLPEDLVRLSVGIEDVDDLISDLDIAFVT 375
|
|
| PRK08574 |
PRK08574 |
cystathionine gamma-synthase family protein; |
21-365 |
1.94e-111 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 236298 [Multi-domain] Cd Length: 385 Bit Score: 330.49 E-value: 1.94e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 21 GTVSAPIYLSTAYRHrgIGEST----GFD--YVRTKNPTRQLVEDAIANLENGARGLAFSSGMAAIQTI-MALFKSGDEL 93
Cdd:PRK08574 18 GSLQPPIYLTALFRQ--EGEAYpsdrGFDlkYSREENPTLRPLEEALAKLEGGVDALAFNSGMAAISTLfFSLLKAGDRV 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 94 IVSSDLYGGTYRLFENeWKKYGLTFHYDDFSDEDCLRSKITPNTKAVFVETPTNPLMQEADIEHIARITKEHGLLLIVDN 173
Cdd:PRK08574 96 VLPMEAYGTTLRLLKS-LEKFGVKVVLAYPSTEDIIEAIKEGRTKLVFIETMTNPTLKVIDVPEVAKAAKELGAILVVDN 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 174 TFYTPVLQRPLELGADIVIHSATKYLGGHNDLLAGLVVVKDERLGEEMFQHQNAIGAVLPPFDSWLLMRGMKTLSLRMRQ 253
Cdd:PRK08574 175 TFATPLLYRPLRHGADFVVHSLTKYIAGHNDVVGGVAVAWSGEFLEELWEWRRRLGTIMQPFEAYLVLRGLKTLEVRFER 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 254 HQANAQELAAFLEEQEEISDVLYPG------------------KGGMLSFRLQ-KEEWVNPFLKALKTICFAESLGGVES 314
Cdd:PRK08574 255 QCRNAMAIAEFLSEHPKVAEVYYPGlpsdpyhgvakrlfgkdlYGGVVSFRVKgGRDAVLKFLRSLKLIKPSPSLGGVES 334
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 906392210 315 FITYPATQTHMDIPEEIRIANGVCNRLLRFSVGIEHAEDLKEDLKQALCQV 365
Cdd:PRK08574 335 LATYPVKSAASPIPEEDRKALGITEDLVRLSVGLEDVEDLIEDLDQALGSI 385
|
|
| PRK08133 |
PRK08133 |
O-succinylhomoserine sulfhydrylase; Validated |
15-362 |
1.93e-108 |
|
O-succinylhomoserine sulfhydrylase; Validated
Pssm-ID: 181244 [Multi-domain] Cd Length: 390 Bit Score: 323.11 E-value: 1.93e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 15 RSDEvtGTVSAPIYLSTAYRH--------RGIGESTGFDYVRTKNPTRQLVEDAIANLENGARGLAFSSGMAAIQ-TIMA 85
Cdd:PRK08133 18 RSPF--GEHSEALFLTSSFVFesaaeaaaRFAGEEPGNIYSRFTNPTVTMFQERLAALEGAEACVATASGMAAILaVVMA 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 86 LFKSGDELIVSSDLYGGTYRLFENEWKKYGLTFHYDDFSDEDCLRSKITPNTKAVFVETPTNPLMQEADIEHIARITKEH 165
Cdd:PRK08133 96 LLQAGDHVVSSRSLFGSTVSLFEKIFARFGIETTFVDLTDLDAWRAAVRPNTKLFFLETPSNPLTELADIAALAEIAHAA 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 166 GLLLIVDNTFYTPVLQRPLELGADIVIHSATKYLGGHNDLLAGLVVVKDERLgEEMFQHQNAIGAVLPPFDSWLLMRGMK 245
Cdd:PRK08133 176 GALLVVDNCFCTPALQQPLKLGADVVIHSATKYLDGQGRVLGGAVVGSKELM-EEVFGFLRTAGPTLSPFNAWVFLKGLE 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 246 TLSLRMRQHQANAQELAAFLEEQEEISDVLYPG----------------KGGMLSFRL---QKEEWvnPFLKALKTICFA 306
Cdd:PRK08133 255 TLSLRMEAHSANALALAEWLEAHPGVERVFYPGlpshpqhelakrqqkgGGAIVSFEVkggREAAW--RVIDATRLISIT 332
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 906392210 307 ESLGGVESFITYPATQTHMDIPEEIRIANGVCNRLLRFSVGIEHAEDLKEDLKQAL 362
Cdd:PRK08133 333 ANLGDTKTTITHPATTTHGRLSPEARAAAGITEGLIRVAVGLEDVADIKADLARGL 388
|
|
| PRK08861 |
PRK08861 |
O-succinylhomoserine (thiol)-lyase; |
6-367 |
3.12e-107 |
|
O-succinylhomoserine (thiol)-lyase;
Pssm-ID: 181567 [Multi-domain] Cd Length: 388 Bit Score: 319.92 E-value: 3.12e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 6 ETKLAQIGNR----SDEVTGTVSAPIYLSTAYRHRGIGESTGFDYVRTKNPTRQLVEDAIANLENGARGLAFSSGMAAIQ 81
Cdd:PRK08861 3 TRKPATIAVRtgieSDSQYHAVVPPIYLSTNYGFPAFGEVPKYDYTRSGNPNRGLLEQTLSELESGKGAVVTNCGTSALN 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 82 TIMALFKSGDELIVSS-DLYGGTYRLFENEWKKYGLTFHYDDFSDEDCLRSKITPNTKAVFVETPTNPLMQEADIEHIAR 160
Cdd:PRK08861 83 LWVSALLGPDDLIVAPhDCYGGTYRLFNTRANKGDFKVQFVDQSDAAALDAALAKKPKLILLETPSNPLVRVVDIAELCQ 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 161 ITKEHGLLLIVDNTFYTPVLQRPLELGADIVIHSATKYLGGHNDLLAGLVVVKDERLGEEMFQHQNAIGAVLPPFDSWLL 240
Cdd:PRK08861 163 KAKAVGALVAVDNTFLTPVLQKPLELGADFVIHSTTKYINGHSDVIGGVLITKTKEHAEELAWWGNCIGATGTPFDSYMT 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 241 MRGMKTLSLRMRQHQANAQELAAFLEEQEEISDVLYP----------------GKGGMLSFRLQKE-EWVNPFLKALKTI 303
Cdd:PRK08861 243 LRGIRTLGARMRVHEESAQQILAYLQTQSLVGTIYHPslpehpgheiakkqqsGFGSMLSFEFAGSfEQLKVFVKALALF 322
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 906392210 304 CFAESLGGVESFITYPATQTHMDIPEEIRIANGVCNRLLRFSVGIEHAEDLKEDLKQALCQVKE 367
Cdd:PRK08861 323 SLAESLGGVESLICHPASMTHRAMGEEALAEAGVSQQLLRLSVGLEDAQDLIADLDQAFAKAAE 386
|
|
| PRK08045 |
PRK08045 |
cystathionine gamma-synthase; Provisional |
8-362 |
4.42e-107 |
|
cystathionine gamma-synthase; Provisional
Pssm-ID: 169194 [Multi-domain] Cd Length: 386 Bit Score: 319.53 E-value: 4.42e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 8 KLAQIGNRS----DEVTGTVSAPIYLSTAYRHRGIGESTGFDYVRTKNPTRQLVEDAIANLENGARGLAFSSGMAAIQTI 83
Cdd:PRK08045 4 KQATIAVRSglndDEQYGCVVPPIHLSSTYNFTGFNEPRAHDYSRRGNPTRDVVQRALAELEGGAGAVLTNTGMSAIHLV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 84 MALF-KSGDELIVSSDLYGGTYRLFENEWKKYGLTFHYDDFSDEDCLRSKITPNTKAVFVETPTNPLMQEADIEHIARIT 162
Cdd:PRK08045 84 TTVFlKPGDLLVAPHDCYGGSYRLFDSLAKRGCYRVLFVDQGDEQALRAALAEKPKLVLVESPSNPLLRVVDIAKICHLA 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 163 KEHGLLLIVDNTFYTPVLQRPLELGADIVIHSATKYLGGHNDLLAGLVVVKDERLGEEMFQHQNAIGAVLPPFDSWLLMR 242
Cdd:PRK08045 164 REAGAVSVVDNTFLSPALQNPLALGADLVLHSCTKYLNGHSDVVAGVVIAKDPDVVTELAWWANNIGVTGGAFDSYLLLR 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 243 GMKTLSLRMRQHQANAQELAAFLEEQEEISDVLYP----------------GKGGMLSFRLQ-KEEWVNPFLKALKTICF 305
Cdd:PRK08045 244 GLRTLVPRMELAQRNAQAIVKYLQTQPLVKKLYHPslpenqgheiaarqqkGFGAMLSFELDgDEQTLRRFLGGLSLFTL 323
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 906392210 306 AESLGGVESFITYPATQTHMDIPEEIRIANGVCNRLLRFSVGIEHAEDLKEDLKQAL 362
Cdd:PRK08045 324 AESLGGVESLISHAATMTHAGMAPEARAAAGISETLLRISTGIEDGEDLIADLENGF 380
|
|
| met_gam_lyase |
TIGR01328 |
methionine gamma-lyase; This model describes a methionine gamma-lyase subset of a family of ... |
3-365 |
6.19e-106 |
|
methionine gamma-lyase; This model describes a methionine gamma-lyase subset of a family of PLP-dependent trans-sulfuration enzymes. The member from the parasite Trichomonas vaginalis is described as catalyzing alpha gamma- and alpha-beta eliminations and gamma-replacement reactions on methionine, cysteine, and some derivatives. Likewise, the enzyme from Pseudomonas degrades cysteine as well as methionine. [Energy metabolism, Amino acids and amines]
Pssm-ID: 130395 [Multi-domain] Cd Length: 391 Bit Score: 316.83 E-value: 6.19e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 3 QHVETKLAQIGNRSDEVTGTVSAPIYLSTAYR--------HRGIGESTGFDYVRTKNPTRQLVEDAIANLENGARGLAFS 74
Cdd:TIGR01328 2 MTFATRAIHAGYPPKDQFGALTPPIYQTSTFVfdsceqggNRFAGQESGYIYSRLGNPTVSNLEGRIAFLEGTEAAVATS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 75 SGMAAIQ-TIMALFKSGDELIVSSDLYGGTYRLFENEWKKYGLTFHYDDFSDEDCLRSKITPNTKAVFVETPTNPLMQEA 153
Cdd:TIGR01328 82 SGMGAIAaTLLTILKAGDHLISDECLYGCTFALLEHALTKFGIQVDFINMAIPEEVKAHIKDNTKIVYFETPANPTMKLI 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 154 DIEHIARITKEHGLLLIVDNTFYTPVLQRPLELGADIVIHSATKYLGGHNDLLAGLVVVKDERLGE-EMFQHQNAIGAVL 232
Cdd:TIGR01328 162 DMERVCRDAHSQGVKVIVDNTFATPMLTNPVALGVDVVVHSATKYIGGHGDVVAGLICGKAELLQQiRMVGIKDMTGSVI 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 233 PPFDSWLLMRGMKTLSLRMRQHQANAQELAAFLEEQEEISDVLYPG----------------KGGMLSFRLQK-EEWVNP 295
Cdd:TIGR01328 242 SPFDAWLILRGLKTLNIRMKRHSENAMKVAEYLKSHPAVEKVYYPGfedhpghdiaakqmrmGGGMITFELKGgFAGAKK 321
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 296 FLKALKTICFAESLGGVESFITYPATQTHMDIPEEIRIANGVCNRLLRFSVGIEHAEDLKEDLKQALCQV 365
Cdd:TIGR01328 322 LLNNLKLIRLAVSLGDAETLIQHPASMTHAVVPKEEREAAGITDGMIRLSVGLEDADDLIADLKQALDAL 391
|
|
| PRK08249 |
PRK08249 |
cystathionine gamma-synthase family protein; |
4-367 |
9.51e-105 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 236202 [Multi-domain] Cd Length: 398 Bit Score: 313.99 E-value: 9.51e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 4 HVETKLAQIGNRSDEVTGTVSAPIYLSTAYRHR--------GIGESTGFDYVRTKNPTRQLVEDAIANLENGARGLAFSS 75
Cdd:PRK08249 8 GVGTKAVWAGEKEYLPYGATQVPVVLSVAYGYDdidewydvALGKKPGHIYSRNTNPTVQAFEEKVRILEGAEAATAFST 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 76 GMAAIQ-TIMALFKSGDELIVSSDLYGGTYRLFENEWKKYGLTFHYDDFSDEDCLRSKITPNTKAVFVETPTNPLMQEAD 154
Cdd:PRK08249 88 GMAAISnTLYTFLKPGDRVVSIKDTYGGTNKIFTEFLPRMGVDVTLCETGDHEQIEAEIAKGCDLLYLETPTNPTLKIVD 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 155 IEHIARITKEHGLLLIVDNTFYTPVLQRPLELGADIVIHSATKYLGGHNDLLAGlVVVKDERLGEEMFQHQNAIGAVLPP 234
Cdd:PRK08249 168 IERLAAAAKKVGALVVVDNTFATPINQNPLALGADLVIHSATKFLSGHADALGG-VVCGSKELMEQVYHYREINGATMDP 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 235 FDSWLLMRGMKTLSLRMRQHQANAQELAAFLEEQEEISDVLYPGK----------------GGMLSFRLQKE-EWVNPFL 297
Cdd:PRK08249 247 MSAYLILRGMKTLKLRVRQQQESAMALAKYLQTHPKVEAVYYPGLethpnheiakaqmrgfGGILSFVLKGGmDTVKRLL 326
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 298 KALKTICFAESLGGVESFITYPATQTHMDIPEEIRIANGVCNRLLRFSVGIEHAEDLKEDLKQALCQVKE 367
Cdd:PRK08249 327 PKLRYAHRAANLGAVETIYGPARTTSHVENTLEERAALGIPEGLVRISVGIEDTEDLIADLEQAFAHLES 396
|
|
| PRK08776 |
PRK08776 |
O-succinylhomoserine (thiol)-lyase; |
4-362 |
2.32e-104 |
|
O-succinylhomoserine (thiol)-lyase;
Pssm-ID: 181554 [Multi-domain] Cd Length: 405 Bit Score: 313.08 E-value: 2.32e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 4 HVETKLAQIGNRSDEVTGTVSAPIYLSTAYRHRGIGESTGFDYVRTKNPTRQLVEDAIANLENGARGLAFSSGMAAIQTI 83
Cdd:PRK08776 12 SAATAAVRAGIDRDTAYGAVTPPIVLSSNFSFDGFGNKRQYDYTRSGNPTRDLLGEALAELEGGAGGVITATGMGAINLV 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 84 M-ALFKSGDELIVSSDLYGGTYRLFENEWKKYGLTFHYDDFSDEDCLRSKITPNTKAVFVETPTNPLMQEADIEHIARIT 162
Cdd:PRK08776 92 LnALLQPGDTLVVPHDAYGGSWRLFNALAKKGHFALITADLTDPRSLADALAQSPKLVLIETPSNPLLRITDLRFVIEAA 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 163 KEHGLLLIVDNTFYTPVLQRPLELGADIVIHSATKYLGGHNDLLAGLVVVKDERLGEEMFQHQNAIGAVLPPFDSWLLMR 242
Cdd:PRK08776 172 HKVGALTVVDNTFLSPALQKPLEFGADLVLHSTTKYINGHSDVVGGAVVARDAELHQQLVWWANALGLTGSPFDAFLTLR 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 243 GMKTLSLRMRQHQANAQELAAFLEEQEEISDVLYPGK----------------GGMLSFRLQK-EEWVNPFLKALKTICF 305
Cdd:PRK08776 252 GLRTLDARLRVHQENADAIAALLDGHAAVNQVYYPGLashpghalaarqqkgfGAMLSFELEGgEAAVRAFVDGLRYFTL 331
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 906392210 306 AESLGGVESFITYPATQTHMDIPEEIRIANGVCNRLLRFSVGIEHAEDLKEDLKQAL 362
Cdd:PRK08776 332 AESLGGVESLIAHPASMTHAAMTAEARAAAGISDGLLRLSVGIESAEDLLIDLRAGL 388
|
|
| PRK07503 |
PRK07503 |
methionine gamma-lyase; Provisional |
21-369 |
3.69e-102 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 181005 [Multi-domain] Cd Length: 403 Bit Score: 307.50 E-value: 3.69e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 21 GTVSAPIYLSTAYRHRGI--------GESTGFDYVRTKNPTRQLVEDAIANLENGARGLAFSSGMAAI-QTIMALFKSGD 91
Cdd:PRK07503 26 GALVPPVYLTATFAFPTAeygaecfaGEEEGHFYSRISNPTLALLEQRMASLEGGEAAVALASGMGAItATLWTLLRPGD 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 92 ELIVSSDLYGGTYRLFENEWKKYGLTFHYDDFSDEDCLRSKITPNTKAVFVETPTNPLMQEADIEHIARITKEHGLLLIV 171
Cdd:PRK07503 106 EVIVDQTLYGCTFAFLHHGLGEFGVTVRHVDLTDPAALKAAISDKTRMVYFETPANPNMRLVDIAAVAEIAHGAGAKVVV 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 172 DNTFYTPVLQRPLELGADIVIHSATKYLGGHNDLLAGLVVVKDERLGE-EMFQHQNAIGAVLPPFDSWLLMRGMKTLSLR 250
Cdd:PRK07503 186 DNTYCTPYLQRPLELGADLVVHSATKYLGGHGDITAGLVVGGKALADRiRLEGLKDMTGAVMSPFDAFLLMRGLKTLALR 265
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 251 MRQHQANAQELAAFLEEQEEISDVLYPG----------------KGGMLSFRLQ-KEEWVNPFLKALKTICFAESLGGVE 313
Cdd:PRK07503 266 MDRHCASAQAVAEWLARHPAVELVHYPGlpsfaqhalaqrqmalPGGMIAFELKgGIAAGRRFMNALQLFARAVSLGDAE 345
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 906392210 314 SFITYPATQTHMDIPEEIRIANGVCNRLLRFSVGIEHAEDLKEDLKQALCQVKEGA 369
Cdd:PRK07503 346 SLAQHPASMTHSTYTPEERAEHGISEGLVRLSVGLEDVADILADLAQALDACAVAA 401
|
|
| OAH_OAS_sulfhy |
TIGR01326 |
OAH/OAS sulfhydrylase; This model describes a distinct clade of the Cys/Met metabolism ... |
4-362 |
3.57e-101 |
|
OAH/OAS sulfhydrylase; This model describes a distinct clade of the Cys/Met metabolism pyridoxal phosphate-dependent enzyme superfamily. Members include examples of OAH/OAS sulfhydrylase, an enzyme with activity both as O-acetylhomoserine (OAH) sulfhydrylase (EC 2.5.1.49) and O-acetylserine (OAS) sulphydrylase (EC 2.5.1.47). An alternate name for OAH sulfhydrylase is homocysteine synthase. This model is designated subfamily because it may or may not have both activities. [Amino acid biosynthesis, Aspartate family, Amino acid biosynthesis, Serine family]
Pssm-ID: 273555 [Multi-domain] Cd Length: 418 Bit Score: 305.44 E-value: 3.57e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 4 HVETKLAQIGNRSDEVTGTVSAPIYLSTAYRHRGIG--------ESTGFDYVRTKNPTRQLVEDAIANLENGARGLAFSS 75
Cdd:TIGR01326 1 HFETLQLHAGQEPDPTTGSRAVPIYQTTSYVFDSTEhaaalfglQEPGNIYSRLMNPTTDVLEQRIAALEGGVAALAVAS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 76 GMAAIQ-TIMALFKSGDELIVSSDLYGGTYRLFENEWKKYGLTFHYDDFSDEDCLRSKITPNTKAVFVETPTNPLMQEAD 154
Cdd:TIGR01326 81 GQAAITyAILNLAGAGDNIVSSSYLYGGTYNLFSHTLKRLGIEVRFVDPDDPESLEKAIDENTKAVFAETIGNPQINVLD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 155 IEHIARITKEHGLLLIVDNTFYTPVLQRPLELGADIVIHSATKYLGGHNDLLAGLVV----------------------- 211
Cdd:TIGR01326 161 IEAIAEVAHRHGIPLIVDNTFATPYLCRPIKHGADIVVHSATKYIGGHGTAIGGVIVdggkfdwnngrfplfttpdpsyh 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 212 --VKDERLGEEMF------QHQNAIGAVLPPFDSWLLMRGMKTLSLRMRQHQANAQELAAFLEEQEEISDVLYPG----- 278
Cdd:TIGR01326 241 glVFTETLGNPAFilkarvQLLRDLGAALSPFNAFLLLQGLETLSLRMERHVENALKVAEFLESHPDVAWVNYPGlashp 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 279 ------------KGGMLSFRLQK-EEWVNPFLKALKTICFAESLGGVESFITYPATQTHMDIPEEIRIANGVCNRLLRFS 345
Cdd:TIGR01326 321 hhalakkylpkgFGAVLSFEIKGgREAGKKFIDALKLASHLANVGDAKSLVIHPASTTHSQLSEEEQLKAGVTPGLIRLS 400
|
410
....*....|....*..
gi 906392210 346 VGIEHAEDLKEDLKQAL 362
Cdd:TIGR01326 401 VGIENIDDIIADLEQAL 417
|
|
| PRK06234 |
PRK06234 |
methionine gamma-lyase; Provisional |
7-362 |
1.94e-99 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 168478 [Multi-domain] Cd Length: 400 Bit Score: 300.59 E-value: 1.94e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 7 TKLAQIGNRSDEVTGTVSAPIYLSTAY--------RHRGIGESTGFDYVRTKNPTRQLVEDAIANLENGARGLAFSSGMA 78
Cdd:PRK06234 11 TKAIHGGHIGDKQFGSLATPIYQTSTFifdsaeqgGRRFAGEESGYIYSRLGNPTSTEVENKLALLEGGEAAVVAASGMG 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 79 AI-QTIMALFKSGDELIVSSDLYGGTYRLFENEWKKYGLTFHYDDFSDEDCLRSKITPNTKAVFVETPTNPLMQEADIEH 157
Cdd:PRK06234 91 AIsSSLWSALKAGDHVVASDTLYGCTFALLNHGLTRYGVEVTFVDTSNLEEVRNALKANTKVVYLETPANPTLKVTDIKA 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 158 IARITKEH--GLLLIVDNTFYTPVLQRPLELGADIVIHSATKYLGGHNDLLAGLVVVKDERLGEEMFQH-QNAIGAVLPP 234
Cdd:PRK06234 171 ISNIAHENnkECLVFVDNTFCTPYIQRPLQLGADVVVHSATKYLNGHGDVIAGFVVGKEEFINQVKLFGiKDMTGSVIGP 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 235 FDSWLLMRGMKTLSLRMRQHQANAQELAAFLEEQEEISDVLYPG----------------KGGMLSFRLQKE-EWVNPFL 297
Cdd:PRK06234 251 FEAFLIIRGMKTLQIRMEKHCKNAMKVAKFLESHPAVEKVYYPGlesfeyyelakkqmslPGAMISFELKGGvEEGKVVM 330
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 906392210 298 KALKTICFAESLGGVESFITYPATQTHMDIPEEIRIANGVCNRLLRFSVGIEHAEDLKEDLKQAL 362
Cdd:PRK06234 331 NNVKLATLAVSLGDAETLIQHPASMTHSPYTAEERKEAGISDGLVRLSVGLEDVDDIIADLKQAL 395
|
|
| PLN02509 |
PLN02509 |
cystathionine beta-lyase |
5-362 |
6.53e-99 |
|
cystathionine beta-lyase
Pssm-ID: 178125 [Multi-domain] Cd Length: 464 Bit Score: 301.18 E-value: 6.53e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 5 VETKLAQIGNRSDEVTGtVSAPIYLSTAYRHRGIGESTGFDYVRTKNPTRQLVEDAIANLENGARGLAFSSGMAAIQTIM 84
Cdd:PLN02509 87 VSTLLVNLDNKFDPFDA-MSTPLYQTATFKQPSAIENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMAALSAVT 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 85 ALFKSGDELIVSSDLYGGTYRLFENEWKKYGLTFHYDDFSDEDCLRSKITPNTKAVFVETPTNPLMQEADIEHIARITKE 164
Cdd:PLN02509 166 HLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNTTNLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKIAEMAHA 245
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 165 HGLLLIVDNTFYTPVLQRPLELGADIVIHSATKYLGGHNDLLAGLVVVKDERLGEEMFQHQNAIGAVLPPFDSWLLMRGM 244
Cdd:PLN02509 246 QGALVLVDNSIMSPVLSRPLELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAKEVYFLQNSEGSGLAPFDCWLCLRGI 325
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 245 KTLSLRMRQHQANAQELAAFLEEQEEISDVLY------PGK----------GGMLSFRLQKEEWVNPFLKALKTICFAES 308
Cdd:PLN02509 326 KTMALRIEKQQENARKIAMYLSSHPRVKKVYYaglpdhPGHhlhfsqakgaGSVFSFITGSVALSKHLVETTKYFSIAVS 405
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 906392210 309 LGGVESFITYPATQTHMDIPEEIRIANGVCNRLLRFSVGIEHAEDLKEDLKQAL 362
Cdd:PLN02509 406 FGSVKSLISMPCFMSHASIPAEVREARGLTEDLVRISAGIEDVDDLISDLDIAF 459
|
|
| PRK06460 |
PRK06460 |
hypothetical protein; Provisional |
17-365 |
1.40e-95 |
|
hypothetical protein; Provisional
Pssm-ID: 235807 [Multi-domain] Cd Length: 376 Bit Score: 289.81 E-value: 1.40e-95
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 17 DEVTGTVSAPIYLSTAYrHRGIGEStgFDYVRTKNPTRQLVEDAIANLENGARGLAFSSGMAAIQT-IMALFKSGDELIV 95
Cdd:PRK06460 13 DEATGAITTPIYQTTAY-HYPEGEK--YRYSREANPTVLELTKKIVELENAEMGVAFSSGMGAISTtALALLKPGNSVLV 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 96 SSDLYGGTYRLFENEWKKYGLTFHYDDFSDEDCLRSKITPNTKAVFVETPTNPLMQEADIEHIARITKEHGLLLIVDNTF 175
Cdd:PRK06460 90 HRDMFGRSYRFFTDYLKNWGVNVDASNPGSDNIIEKAKSKRYDVVFVENITNPLLRVVDITELSKVCKENGSILIVDATF 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 176 YTPVLQRPLELGADIVIHSATKYLGGHNDLLAGLVVVKDErLGEEMFQHQNAIGAVLPPFDSWLLMRGMKTLSLRMRQHQ 255
Cdd:PRK06460 170 STPINQKPLELGADIVVHSASKFLAGHNDVIAGLAAGYGK-LLNVIDQMRRTLGTSLDPHAAYLTLRGIKTLKIRMDVIN 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 256 ANAQELAAFLEEQEEISDVLYPG----------------KGGMLSFRLQK--EEWVNpFLKALKTICFAESLGGVESFIT 317
Cdd:PRK06460 249 RNAEQIAEFLEGHPKVVKVYYPGlkshvdyeiarrvlkgFGGVLSFEVNGgqESALK-VMKSLKLIIPAQTLGGVNSVIS 327
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 906392210 318 YPATQTHMDI-PEEIRIAnGVCNRLLRFSVGIEHAEDLKEDLKQALCQV 365
Cdd:PRK06460 328 HPATMSHRTLsLEERKIV-GITDSLLRLSVGIEDVNDLIEDLDRALSTL 375
|
|
| PRK07812 |
PRK07812 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
6-366 |
2.65e-91 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 236105 Cd Length: 436 Bit Score: 280.87 E-value: 2.65e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 6 ETKLAQIGNRSDEVTGTVSAPIYLSTAYRHR---------GIGEsTGFDYVRTKNPTRQLVEDAIANLENGARGLAFSSG 76
Cdd:PRK07812 15 ETKQIHAGQTPDPATNARALPIYQTTSYTFDdtdhaaalfGLAE-PGNIYTRIMNPTQDVVEQRIAALEGGVAALLLASG 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 77 MAAIQ-TIMALFKSGDELIVSSDLYGGTYRLFENEWKKYGLTFHY-DDFSDEDCLRSKITPNTKAVFVETPTNPLMQEAD 154
Cdd:PRK07812 94 QAAETfAILNLAGAGDHIVSSPRLYGGTYNLFHYTLPKLGIEVSFvEDPDDLDAWRAAVRPNTKAFFAETISNPQIDVLD 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 155 IEHIARITKEHGLLLIVDNTFYTPVLQRPLELGADIVIHSATKYLGGHNDLLAGLVV----------------------- 211
Cdd:PRK07812 174 IPGVAEVAHEAGVPLIVDNTIATPYLIRPLEHGADIVVHSATKYLGGHGTAIAGVIVdggtfdwtqgrfpgfttpdpsyh 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 212 -VKDERLGEEMF------QHQNAIGAVLPPFDSWLLMRGMKTLSLRMRQHQANAQELAAFLEEQEEISDVLYP------- 277
Cdd:PRK07812 254 gVVFAELGPPAYalkarvQLLRDLGSAISPFNAFLIAQGLETLSLRIERHVANAQRVAEFLEARDEVASVNYAglpsspw 333
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 278 ----------GKGGMLSFRLQKE-EWVNPFLKALKTICFAESLGGVESFITYPATQTHMDIPEEIRIANGVCNRLLRFSV 346
Cdd:PRK07812 334 yerakrlapkGTGAVLSFELAGGvEAGKAFVNALTLHSHVANIGDVRSLVIHPASTTHSQLTPEEQLATGVTPGLVRLAV 413
|
410 420
....*....|....*....|
gi 906392210 347 GIEHAEDLKEDLKQALCQVK 366
Cdd:PRK07812 414 GIEGIDDILADLEAGFAAAK 433
|
|
| PRK06434 |
PRK06434 |
cystathionine gamma-lyase; Validated |
7-362 |
4.27e-89 |
|
cystathionine gamma-lyase; Validated
Pssm-ID: 102374 [Multi-domain] Cd Length: 384 Bit Score: 273.32 E-value: 4.27e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 7 TKLAQIGNRSDEVTGTVSAPIYLSTAY------RHRGIGESTGFDYVRTK--NPTRQLVEDAIANLENGARGLAFSSGMA 78
Cdd:PRK06434 11 TRAVQSGELRDPRFGNVTTPIFETSTFvypnseKEAYMDSTRGMPYIYTRwgNPTVQAFEEKYAVLENAEHALSFSSGMG 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 79 AIQT-IMALFKSGDELIVSSDLYGGTYRLFENEWKKYGLTFhydDFSDEDCLRS-KITP-NTKAVFVETPTNPLMQEADI 155
Cdd:PRK06434 91 AITSaILSLIKKGKRILSISDLYGQTFYFFNKVLKTLGIHV---DYIDTDRLNSlDFDPsNYDLIYAESITNPTLKVPDI 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 156 EHIAriTKEHGLLLIVDNTFYTPVLQRPLELGADIVIHSATKYLGGHNDLLAGLVVVKDERLGEEMFQHQNAIGAVLPPF 235
Cdd:PRK06434 168 KNVS--SFCHENDVIVDATFASPYNQNPLDLGADVVIHSATKYISGHSDVVMGVAGTNNKSIFNNLVERRKTLGSNPDPI 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 236 DSWLLMRGMKTLSLRMRQHQANAQELAAFLEEQEEISDVLYP----------GKGGMLSFRLQKEEWVNPFLKALKTICF 305
Cdd:PRK06434 246 QAYLALRGLKTLGLRMEKHNKNGMELARFLRDSKKISNVYYPdteigkkvlrGFGGMLSFELRSMEDVHKFIRNLEIPMV 325
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 906392210 306 AESLGGVESFITYPATQTHMDIPEEIRIANGVCNRLLRFSVGIEHAEDLKEDLKQAL 362
Cdd:PRK06434 326 AASLGGVESLITLPVETSHSSLSPEERERLGISDNLVRFSIGIEDIDDLIKDIENAL 382
|
|
| PRK08248 |
PRK08248 |
homocysteine synthase; |
5-362 |
1.10e-86 |
|
homocysteine synthase;
Pssm-ID: 236201 [Multi-domain] Cd Length: 431 Bit Score: 268.64 E-value: 1.10e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 5 VETKLAQIGNRSDEVTGTVSAPIYLSTAYRHRGIGEST--------GFDYVRTKNPTRQLVEDAIANLENGARGLAFSSG 76
Cdd:PRK08248 9 LETLAIHAGQEIDPTTGSRAVPIYQTTSYGFRDSEHAAnlfslkefGNIYTRIMNPTTDVFEKRIAALEGGIGALAVSSG 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 77 MAAIQ-TIMALFKSGDELIVSSDLYGGTYRLFENEWKKYGLTFHYDDFSDEDCLRSKITPNTKAVFVETPTNPLMQEADI 155
Cdd:PRK08248 89 QAAITySILNIASAGDEIVSSSSLYGGTYNLFAHTLPKLGITVKFVDPSDPENFEAAITDKTKALFAETIGNPKGDVLDI 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 156 EHIARITKEHGLLLIVDNTFYTPVLQRPLELGADIVIHSATKYLGGHNDLLAGLVV------------------------ 211
Cdd:PRK08248 169 EAVAAIAHEHGIPLIVDNTFASPYLLRPIEHGADIVVHSATKFIGGHGTSIGGVIVdsgkfdwkgsgkfpgltepdpsyh 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 212 --VKDERLGEEMF------QHQNAIGAVLPPFDSWLLMRGMKTLSLRMRQHQANAQELAAFLEEQEEISDVLYP------ 277
Cdd:PRK08248 249 glVYTDAVGEAAYitkarvQLLRDLGAALSPFNSFLLLQGLETLHLRMERHSENALAVAKFLEEHEAVEWVSYPglpshp 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 278 -----------GKGGMLSFRLQ-KEEWVNPFLKALKTICFAESLGGVESFITYPATQTHMDIPEEIRIANGVCNRLLRFS 345
Cdd:PRK08248 329 syelakkylpkGQGAILTFGIKgGVEAGKKLIDSVKLFSHLANVGDSKSLIIHPASTTHQQLSEEEQLAAGVTPGLVRLS 408
|
410
....*....|....*..
gi 906392210 346 VGIEHAEDLKEDLKQAL 362
Cdd:PRK08248 409 VGTEAIDDILDDLRQAI 425
|
|
| PRK05968 |
PRK05968 |
hypothetical protein; Provisional |
39-362 |
4.00e-83 |
|
hypothetical protein; Provisional
Pssm-ID: 168320 [Multi-domain] Cd Length: 389 Bit Score: 258.09 E-value: 4.00e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 39 GESTGFDYVRTKNPTRQLVEDAIANLENGARGLAFSSGMAAIQ-TIMALFKSGDELIVSSDLYGGTYRLFENEWKKYGLT 117
Cdd:PRK05968 50 GEKVRPIYSRGDNPTVRAFEEMLAKLEGAEDARGFASGMAAISsTVLSFVEPGDRIVAVRHVYPDAFRLFETILKRMGVE 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 118 FHYDDFSDEDCLRsKITPNTKAVFVETPTNPLMQEADIEHIARITKEHGLLLIVDNTFYTPVLQRPLELGADIVIHSATK 197
Cdd:PRK05968 130 VDYVDGRDEEAVA-KALPGAKLLYLESPTSWVFELQDVAALAALAKRHGVVTMIDNSWASPVFQRPITLGVDLVIHSASK 208
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 198 YLGGHNDLLAGLVVVKDE---RLGEEMFQHqnaIGAVLPPFDSWLLMRGMKTLSLRMRQHQANAQELAAFLEEQEEISDV 274
Cdd:PRK05968 209 YLGGHSDTVAGVVAGSKEhiaRINAEAYPY---LGAKLSPFEAWLLLRGLRTLPLRMKAHEASALEIARRLKAHPVVERV 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 275 LYP-----------GKGGMLSFRLQKEEWVNPFLKALKTICFAESLGGVESFITyPAtqthmDIPEEIR------IANGV 337
Cdd:PRK05968 286 CHPalanhppaglsGTSGLFSFIFREGIDVRAFADALKLFRLGVSWGGHESLVV-PA-----EVVLQQKaqpnsaARFGV 359
|
330 340
....*....|....*....|....*
gi 906392210 338 CNRLLRFSVGIEHAEDLKEDLKQAL 362
Cdd:PRK05968 360 SPRSVRLHVGLEGTEALWADLEQAL 384
|
|
| PRK07504 |
PRK07504 |
O-succinylhomoserine sulfhydrylase; Reviewed |
6-366 |
3.55e-82 |
|
O-succinylhomoserine sulfhydrylase; Reviewed
Pssm-ID: 168979 [Multi-domain] Cd Length: 398 Bit Score: 256.22 E-value: 3.55e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 6 ETKLAQIGN-RSDevTGTVSAPIYLSTAYRH--------RGIGESTGFDYVRTKNPTRQLVEDAIANLENGARGLAFSSG 76
Cdd:PRK07504 12 ATRLVHSGTlRSQ--FGETSEALFLTQGFVYdtaeaaeaRFKGEDPGFIYSRYSNPTVDMFEKRMCALEGAEDARATASG 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 77 MAAIQT-IMALFKSGDELIVSSDLYGGTYRLFENEWKKYGLTFHYDDFSDEDCLRSKITPNTKAVFVETPTNPLMQEADI 155
Cdd:PRK07504 90 MAAVTAaILCQVKAGDHVVAARALFGSCRYVVETLLPRYGIESTLVDGLDLDNWEKAVRPNTKVFFLESPTNPTLEVIDI 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 156 EHIARITKEHGLLLIVDNTFYTPVLQRPLELGADIVIHSATKYLGGHNDLLAGLVVVKDERLGEEMFQHQNAIGAVLPPF 235
Cdd:PRK07504 170 AAVAKIANQAGAKLVVDNVFATPLFQKPLELGAHIVVYSATKHIDGQGRCLGGVVLSDKAWIEEHLQDYFRHTGPSLSPF 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 236 DSWLLMRGMKTLSLRMRQHQANAQELAAFLEEQEEISDVLYPG--------------KGG--MLSFRLQ--KEEWVNpFL 297
Cdd:PRK07504 250 NAWTLLKGLETLPVRVRQQTESAAAIADFLAGHPKVARVIYPGradhpqadiiakqmTGGstLVAFELKggKEAAFR-FL 328
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 906392210 298 KALKTICFAESLGGVESFITYPATQTHMDIPEEIRIANGVCNRLLRFSVGIEHAEDLKEDLKQALCQVK 366
Cdd:PRK07504 329 NALKIVRISNNLGDAKSLITHPATTTHKNLSPEARAELGISEGFLRLSAGLEDTDDLIEDLAAALKKVR 397
|
|
| PRK07582 |
PRK07582 |
cystathionine gamma-lyase; Validated |
23-362 |
6.66e-80 |
|
cystathionine gamma-lyase; Validated
Pssm-ID: 236061 Cd Length: 366 Bit Score: 249.14 E-value: 6.66e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 23 VSAPIYLSTAYrHRGIGESTGFD-YVRTKNPTRQLVEDAIANLEnGARGLAFSSGMAAIQ-TIMALFKSGDELIVSSDLY 100
Cdd:PRK07582 22 VLPGPVFAAPY-HLSPGEPTGPDtYGRASNPTWRALEAALGELE-GAEALVFPSGMAAITaVLRALLRPGDTVVVPADGY 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 101 GGTYRLFENEWKKYGLTFHY--------DDFSDedclrskitpnTKAVFVETPTNPLMQEADIEHIARITKEHGLLLIVD 172
Cdd:PRK07582 100 YQVRALAREYLAPLGVTVREaptagmaeAALAG-----------ADLVLAETPSNPGLDVCDLAALAAAAHAAGALLVVD 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 173 NTFYTPVLQRPLELGADIVIHSATKYLGGHNDLLAGLVVVKDERLGEEMFQHQNAIGAVLPPFDSWLLMRGMKTLSLRMR 252
Cdd:PRK07582 169 NTTATPLGQRPLELGADLVVASDTKALTGHSDLLLGYVAGRDPELMAAVERWRLLAGAIPGPFEAWLAHRSLGTLGLRFA 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 253 QHQANAQELAAFLEEQEEISDVLYPGK----------------GGMLSFRLQKEEWVNPFLKALKTICFAESLGGVesfi 316
Cdd:PRK07582 249 RQCANALAVAELLAGHPAVRGVRYPGLpgdpahevaarqmrrfGGLVSFELADAAAAERFVAASRLVVAATSFGGV---- 324
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 906392210 317 typatqtHMDIPEEIRIANGVCNRLLRFSVGIEHAEDLKEDLKQAL 362
Cdd:PRK07582 325 -------HTSADRRARWGDAVPEGFVRLSCGIEDTDDLVADLERAL 363
|
|
| PRK08134 |
PRK08134 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
13-362 |
2.88e-77 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 236159 Cd Length: 433 Bit Score: 244.65 E-value: 2.88e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 13 GNRSDEVTGTVSAPIYLSTAYRHRGIG--------ESTGFDYVRTKNPTRQLVEDAIANLENGARGLAFSSGMAAIQ-TI 83
Cdd:PRK08134 17 GAAPDPATGARAVPIHLTTSFVFRDSDhaaalfnlERAGHVYSRISNPTVAVLEERVAALEGGVGAIATASGQAALHlAI 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 84 MALFKSGDELIVSSDLYGGTYRLFENEWKKYGLTFHYDDFSDEDCLRSKITPNTKAVFVETPTNPLMQEADIEHIARITK 163
Cdd:PRK08134 97 ATLMGAGSHIVASSALYGGSHNLLHYTLRRFGIETTFVKPGDIDGWRAAIRPNTRLLFGETLGNPGLEVLDIPTVAAIAH 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 164 EHGLLLIVDNTFYTPVLQRPLELGADIVIHSATKYLGGHNDLLAGLVV--------------------------VKDERL 217
Cdd:PRK08134 177 EAGVPLLVDSTFTTPYLLRPFEHGADLVYHSATKFLGGHGTAIGGVLVdggrfdweasgkfpeltepyagfhgmVFAEES 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 218 GEEMF------QHQNAIGAVLPPFDSWLLMRGMKTLSLRMRQHQANAQELAAFLEEQEEISDVLYP-------------- 277
Cdd:PRK08134 257 TVAAFllrarrEGLRDFGACLSPMNAWQLLQGIETLPLRMERHVANTRKVVAFLASHPAVARVAHPeleshpdhalakrl 336
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 278 ---GKGGMLSFRLQ-KEEWVNPFLKALKTICFAESLGGVESFITYPATQTHMDIPEEIRIANGVCNRLLRFSVGIEHAED 353
Cdd:PRK08134 337 lprGAGSVFSFDLKgGRAAGRKFIESLKLFSHLANVGDARSLVIHPASTTHFRMDAAALAAAGIGEGTIRLSIGLEDADD 416
|
....*....
gi 906392210 354 LKEDLKQAL 362
Cdd:PRK08134 417 LIDDLKRAL 425
|
|
| PRK05994 |
PRK05994 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
13-362 |
2.28e-75 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 180344 [Multi-domain] Cd Length: 427 Bit Score: 239.61 E-value: 2.28e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 13 GNRSDEVTGTVSAPIYLSTAYRHRGIG--------ESTGFDYVRTKNPTRQLVEDAIANLENGARGLAFSSGMAA-IQTI 83
Cdd:PRK05994 16 GAQPDPTTGARATPIYQTTSFVFNDADhaaslfglQAFGNIYTRITNPTNAVLEERVAALEGGTAALAVASGHAAqFLVF 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 84 MALFKSGDELIVSSDLYGGTYRLFENEWKKYGLTFHYDDFSDEDCLRSKITPNTKAVFVETPTNPLMQEADIEHIARITK 163
Cdd:PRK05994 96 HTLLQPGDEFIAARKLYGGSINQFGHAFKSFGWQVRWADADDPASFERAITPRTKAIFIESIANPGGTVTDIAAIAEVAH 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 164 EHGLLLIVDNTFYTPVLQRPLELGADIVIHSATKYLGGHNDLLAGLVV-------VKDER---------------LGEEM 221
Cdd:PRK05994 176 RAGLPLIVDNTLASPYLIRPIEHGADIVVHSLTKFLGGHGNSMGGIIVdggtfdwSKSGKypmlseprpeyhglvLHETF 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 222 FQHQNAI----------GAVLPPFDSWLLMRGMKTLSLRMRQHQANAQELAAFLEEQEEISDVLYPG------------- 278
Cdd:PRK05994 256 GNFAFAIaarvlglrdlGPAISPFNAFLILTGIETLPLRMQRHSDNALAVAEWLKGHPKVSWVNYAGlpddpyhalaqky 335
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 279 ----KGGMLSFRLQK--EEWVNpFLKALKTICFAESLGGVESFITYPATQTHMDIPEEIRIANGVCNRLLRFSVGIEHAE 352
Cdd:PRK05994 336 spkgAGAVFTFGLKGgyEAGVK-LVSSLKLFSHLANIGDTRSLVIHPASTTHRQLTDEQKVAAGAGPDVVRLSIGIEDVD 414
|
410
....*....|
gi 906392210 353 DLKEDLKQAL 362
Cdd:PRK05994 415 DIIADLEQAL 424
|
|
| PRK07049 |
PRK07049 |
cystathionine gamma-synthase family protein; |
21-362 |
3.68e-75 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 180809 [Multi-domain] Cd Length: 427 Bit Score: 238.80 E-value: 3.68e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 21 GTVSAPIYLSTAY------------------RHRGIGESTGFDYVRTKNPTRQLVEDAIANLENGARGLAFSSGMAAIQT 82
Cdd:PRK07049 34 GAVKPPVFLTSTFvfrsaedgrdffdyvsgrKEPPAGEGAGLVYSRFNHPNSEIVEDRLAVYEGAESAALFSSGMSAIAT 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 83 IM-ALFKSGDELIVSSDLYGGTYRLFENEWKKYGLTFH-YDDFSDEDCLRSKITP-----NTKAVFVETPTNPLMQEADI 155
Cdd:PRK07049 114 TLlAFVRPGDVILHSQPLYGGTETLLAKTFRNFGVGAVgFADGLSEAAIGAAAEAaaakgRVSLILIETPANPTNSLVDV 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 156 EHIARIT------KEHGLLLIVDNTFYTPVLQRPLELGADIVIHSATKYLGGHNDLLAGlVVVKDERLGEEMFQHQNAIG 229
Cdd:PRK07049 194 AAVRRVAdaiearQGHRPIIACDNTLLGPVFQKPLEHGADLSVYSLTKYVGGHSDLVAG-AVLGRKALIRQVRALRSAIG 272
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 230 AVLPPFDSWLLMRGMKTLSLRMRQHQANAQELAAFLEEQEEISDVLYP------------------GKGGMLSFRLQK-E 290
Cdd:PRK07049 273 TQLDPHSCWMLGRSLETLVLRMERANRNARAVAEFLRDHPKVEKLHYLpfldpdsaygavykrqctGAGSTFSFDIKGgQ 352
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 906392210 291 EWVNPFLKALKTICFAESLGGVESFITYPATQTHMDIPEEIRIANGVCNRLLRFSVGIEHAEDLKEDLKQAL 362
Cdd:PRK07049 353 AAAFRFLNALQIFKLAVSLGGTESLASHPASMTHSGVPADVRERIGVLESTIRLSIGIEHPDDLIADLAQAL 424
|
|
| PRK06084 |
PRK06084 |
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; |
5-362 |
9.41e-73 |
|
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase;
Pssm-ID: 180392 [Multi-domain] Cd Length: 425 Bit Score: 232.48 E-value: 9.41e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 5 VETKLAQIGNRSDEVTGTVSAPIYLSTAYRHRGIGESTG-FD-------YVRTKNPTRQLVEDAIANLENGARGLAFSSG 76
Cdd:PRK06084 3 LETLAIHAGYSPDPTTKAVAVPIYQTTSYAFDDTQHGADlFDlkvpgniYTRIMNPTNDVLEQRVAALEGGVGALAVASG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 77 MAAIQ-TIMALFKSGDELIVSSDLYGGTYRLFENEWKKYGLTFHYDDFSDEDCLRSKITPNTKAVFVETPTNPLMQEADI 155
Cdd:PRK06084 83 MAAITyAIQTIAEAGDNIVSVAKLYGGTYNLLAHTLPRIGIETRFAAHDDIAALEALIDERTKAVFCESIGNPAGNIIDI 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 156 EHIARITKEHGLLLIVDNTFYTPVLQRPLELGADIVIHSATKYLGGHNDLLAGLVV------------------------ 211
Cdd:PRK06084 163 QALADAAHRHGVPLIVDNTVATPVLCRPFEHGADIVVHSLTKYIGGHGTSIGGIVVdsgkfpwaehkerfallntpdpsy 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 212 ---VKDERLGEEMFQHQ------NAIGAVLPPFDSWLLMRGMKTLSLRMRQHQANAQELAAFLEEQEEISDVLYPG---- 278
Cdd:PRK06084 243 hgvTYTEAFGPAAFIGRcrvvplRNMGAALSPFNAFLILQGLETLALRMERHTENALKVARYLQQHPQVAWVKYAGlpdh 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 279 -------------KGGMLSFRLQKEEWVNP-FLKALKTICFAESLGGVESFITYPATQTHMDIPEEIRIANGVCNRLLRF 344
Cdd:PRK06084 323 pehelarrymggkPASILSFGIKGGQAAGArFIDALKLVVRLVNIGDAKSLACHPASTTHRQLNDEELEKAGVSRDMVRL 402
|
410
....*....|....*...
gi 906392210 345 SVGIEHAEDLKEDLKQAL 362
Cdd:PRK06084 403 SIGIEHIDDIIADLAQAL 420
|
|
| PRK05939 |
PRK05939 |
cystathionine gamma-synthase family protein; |
21-362 |
9.86e-71 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 235650 [Multi-domain] Cd Length: 397 Bit Score: 226.49 E-value: 9.86e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 21 GTVSAPIYLSTAYRH---RGI-----GESTGFDYVRTKNPTRQLVEDAIANLENGARGLAFSSGMAAIQTI-MALFKSGD 91
Cdd:PRK05939 8 GAVHKPIHTSVTYGYedaRDLidvfqGKKPGFTYARQGTPTTAALEAKITKMEGGVGTVCFATGMAAIAAVfLTLLRAGD 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 92 ELIVSSDLYGGTYRLFENeWKKYGLTFHYDDFSDEDCLRSKITPNTKAVFVETPTNPLMQEADIEHIARITKEHGLLLIV 171
Cdd:PRK05939 88 HLVSSQFLFGNTNSLFGT-LRGLGVEVTMVDATDVQNVAAAIRPNTRMVFVETIANPGTQVADLAGIGALCRERGLLYVV 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 172 DNTFYTPVLQRPLELGADIVIHSATKYLGGHNDLLAGLVV------------VKDE-RLGEEMFQHQNAI--------GA 230
Cdd:PRK05939 167 DNTMTSPWLFRPKDVGASLVINSLSKYIAGHGNALGGAVTdtglfdwsaypnIFPAyRKGDPQQWGLTQIrkkglrdmGA 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 231 VLPPFDSWLLMRGMKTLSLRMRQHQANAQELAAFLEEQEEISDVLYPG----------------KGGMLSFRLQKEEWVN 294
Cdd:PRK05939 247 TLSSEAAHRIAIGAETLALRVDRSCSNALALAQFLEAHPKVARVYYPGlashpqharatelfrhYGGLLSFELADGIDCF 326
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 906392210 295 PFLKALKTICFAESLGGVESFITyPATQT-HMDIPEEIRIANGVCNRLLRFSVGIEHAEDLKEDLKQAL 362
Cdd:PRK05939 327 DFLNRLKLVIKATHLGDTRTLVI-PVAPTiYYEMGAERRASMGIADSLIRVSVGIEDEADLIADFEQAL 394
|
|
| PRK05613 |
PRK05613 |
O-acetylhomoserine/O-acetylserine sulfhydrylase; |
6-365 |
7.77e-69 |
|
O-acetylhomoserine/O-acetylserine sulfhydrylase;
Pssm-ID: 168128 [Multi-domain] Cd Length: 437 Bit Score: 222.82 E-value: 7.77e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 6 ETKLAQIGNRSDEVTGTVSAPIYLSTAY--------RHRGIGESTGFDYVRTKNPTRQLVEDAIANLENGARGLAFSSGM 77
Cdd:PRK05613 15 ETRSIHAGQSVDSDTSARNLPIYQTTSYvfdsaehaKQRFALEDLGPIYSRLTNPTVEALENRIASLEGGVHAVAFASGQ 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 78 AAIQT-IMALFKSGDELIVSSDLYGGTYRLFENEWKKYGLTFHY-DDFSDEDCLRSKITPNTKAVFVETPTNPLMQEADI 155
Cdd:PRK05613 95 AAETAaILNLAGAGDHIVTSPRLYGGTETLFLVTLNRLGIEVTFvENPDDPESWQAAVQPNTKAFFGETFANPQADVLDI 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 156 EHIARITKEHGLLLIVDNTFYTPVLQRPLELGADIVIHSATKYLGGHNDLLAGLVV------------------------ 211
Cdd:PRK05613 175 PAVAEVAHRNQVPLIVDNTIATAALVRPLELGADVVVASLTKFYTGNGSGLGGVLIdggkfdwtverdgkpvfpyfvtpd 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 212 -----VKDERLGEEMFQHQNAI------GAVLPPFDSWLLMRGMKTLSLRMRQHQANAQELAAFLEEQEEISDVLYPG-- 278
Cdd:PRK05613 255 payhgLKYADLGAPAFGLKARAgllrdtGATLSPFNAWVTAQGLDTLSLRLERHNENAIKVAEFLNNHEKVAKVNFAGlk 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 279 ---------------KGGMLSFRL---QKEEWVnpFLKALKTICFAESLGGVESFITYPATQTHMDIPEEIRIANGVCNR 340
Cdd:PRK05613 335 dspwyatkeklglkyTGSVLSFDIkggKDEAWA--FIDALKLHSNLANIGDVRSLVVHPATTTHSQSDEAGLARAGITQA 412
|
410 420
....*....|....*....|....*
gi 906392210 341 LLRFSVGIEHAEDLKEDLKQALCQV 365
Cdd:PRK05613 413 TVRLSVGIEDIDDIIADLEGGFAAI 437
|
|
| PRK07810 |
PRK07810 |
O-succinylhomoserine sulfhydrylase; Provisional |
24-362 |
4.67e-68 |
|
O-succinylhomoserine sulfhydrylase; Provisional
Pssm-ID: 236103 [Multi-domain] Cd Length: 403 Bit Score: 219.61 E-value: 4.67e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 24 SAPIYLSTAYRHRG--------IGESTGFDYVRTKNPTRQLVEDAIANLENGARGLAFSSGMAAIQTIM-ALFKSGDELI 94
Cdd:PRK07810 34 AEALYLTSGYVYESaaaaeaafTGELDRFVYSRYGNPTVSMFEERLRLIEGAEACFATASGMSAVFTALgALLGAGDRLV 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 95 VSSDLYGGTYRLFENEWKKYGLTFHYDDFSDEDCLRSKITPNTKAVFVETPTNPLMQEADIEHIARITKEHGLLLIVDNT 174
Cdd:PRK07810 114 AARSLFGSCFVVCNEILPRWGVETVFVDGEDLSQWEEALSVPTQAVFFETPSNPMQSLVDIAAVSELAHAAGAKVVLDNV 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 175 FYTPVLQRPLELGADIVIHSATKYLGGHNDLLAGLVVVKDERLGEEMFQHQNAIGAVLPPFDSWLLMRGMKTLSLRMRQH 254
Cdd:PRK07810 194 FATPLLQRGLPLGADVVVYSGTKHIDGQGRVLGGAILGDREYIDGPVQKLMRHTGPALSAFNAWVLLKGLETLALRVRHS 273
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 255 QANAQELAAFLEEQEEISDVLYP----------------GKGGMLSFRLQKEEWVNP-----FLKALKTICFAESLGGVE 313
Cdd:PRK07810 274 NASALRIAEFLEGHPAVRWVRYPflpshpqydlakrqmsGGGTVVTFELDAPEDAAKkrafeVLDKLRVIDISNNLGDAK 353
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 906392210 314 SFITYPATQTHMDIPEEIRIANGVCNRLLRFSVGIEHAEDLKEDLKQAL 362
Cdd:PRK07810 354 SLITHPATTTHRAMGPEGRAAIGLGDGVVRLSVGLEDTDDLIADLDRAL 402
|
|
| cysta_beta_ly_B |
TIGR01324 |
cystathionine beta-lyase, bacterial; This model represents cystathionine beta-lyase (alternate ... |
7-362 |
5.33e-61 |
|
cystathionine beta-lyase, bacterial; This model represents cystathionine beta-lyase (alternate name: beta-cystathionase), one of several pyridoxal-dependent enzymes of cysteine, methionine, and homocysteine metabolism. This enzyme is involved in the biosynthesis of Met from Cys. [Amino acid biosynthesis, Aspartate family]
Pssm-ID: 130391 [Multi-domain] Cd Length: 377 Bit Score: 200.87 E-value: 5.33e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 7 TKLAQIGNRSDEVTGTVSAPI-------YLSTAYRHRGIGESTgfdYVRTKNPTRQLVEDAIANLENGARGLAFSSGMAA 79
Cdd:TIGR01324 1 TRLIHSGRQPRFSQGSVNPPLqrastvlFDSHAAQRRAKGELT---YGRRGTLTHFALQDAMCELEGGAGCYLYPSGLAA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 80 IQ-TIMALFKSGDELIVSSDLYGGTYRLFENEWKKYGLTFHYDDFSDEDCLRSKITPNTKAVFVETPTNPLMQEADIEHI 158
Cdd:TIGR01324 78 VTnSILAFVKAGDHVLMVDSAYEPTRYFCDIVLKRMGVDITYYDPLIGEDIATLIQPNTKVLFLEAPSSITFEIQDIPAI 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 159 ARITKEHGLLLIVDNTFYTPVLQRPLELGADIVIHSATKYLGGHNDLLAGlVVVKDERLGEEMFQHQNAIGAVLPPFDSW 238
Cdd:TIGR01324 158 AKAARNPGIVIMIDNTWAAGLLFKPLEHGVDISIQAGTKYLVGHSDIMIG-TVVANARTWDQLREHSYLMGQMVDADDAY 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 239 LLMRGMKTLSLRMRQHQANAQELAAFLEEQEEISDVLYP----------------GKGGMLSFRLQK--EEWVNPFLKAL 300
Cdd:TIGR01324 237 TTLRGLRTLGVRLKQHQESSLAIAKWLSEQPEVARVLHPalpscpghefwkrdfsGSSGLFSFVLQRltQKQVHAFLDHL 316
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 906392210 301 KTICFAESLGGVESFitypATQTHMDIPEEIRIANGVCNRLLRFSVGIEHAEDLKEDLKQAL 362
Cdd:TIGR01324 317 QLFGLGYSWGGYESL----ALCNQPELGHRPNIKRNLEGPLIRVHIGLENVDDLKADLKAGF 374
|
|
| PRK09028 |
PRK09028 |
cystathionine beta-lyase; Provisional |
1-362 |
8.53e-53 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 181615 [Multi-domain] Cd Length: 394 Bit Score: 179.93 E-value: 8.53e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 1 MSQHVETKLAQIGNRSDEVTGTVSAPIYLSTAY--------RHRGIGESTG-FDYVRTKNPTRQLVEDAIANLENGARGL 71
Cdd:PRK09028 1 MSEKKATKIVSAGRDKKWTKGVINPPVFRASTVvfdtvaemRHAAKNRANGeMFYGRRGTPTHFAFQAAIVELEGGAGTA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 72 AFSSGMAAIQ-TIMALFKSGDELIVSSDLYGGTYRLFENEWKKYGL-TFHYDDFSDEDcLRSKITPNTKAVFVETPTNPL 149
Cdd:PRK09028 81 LYPSGAAAISnALLSFLKAGDHLLMVDSCYEPTRDLCDKILKGFGIeTTYYDPMIGEG-IRELIRPNTKVLFLESPGSIT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 150 MQEADIEHIARITKEHGLLLIVDNTFYTPVLQRPLELGADIVIHSATKYLGGHNDLLAGlVVVKDERLGEEMFQHQNAIG 229
Cdd:PRK09028 160 MEVQDVPTLSRIAHEHDIVVMLDNTWASPINSRPFEMGVDISIQAATKYIVGHSDVMLG-TATANEKHWDQLREHSYLMG 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 230 AVLPPFDSWLLMRGMKTLSLRMRQHQANAQELAAFLEEQEEISDVLYP----------------GKGGMLSFRLQK--EE 291
Cdd:PRK09028 239 QCTSPDDVYLAMRGLRTLGVRLAQHEKNALKVANWLATRPEVDHVRHPafetcpgheffkrdfsGSNGLFSFVLKQgdPK 318
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 906392210 292 WVNPFLKALKTICFAESLGGVESFITypatqTHMDIpEEIRIAN--GVCNRLLRFSVGIEHAEDLKEDLKQAL 362
Cdd:PRK09028 319 AVTALVEGMQHFKMGFSWGGFESLIL-----GVFGI-NKLRTATnwDFSKPLIRLHIGLEDVDDLIADLEAGF 385
|
|
| PRK05967 |
PRK05967 |
cystathionine beta-lyase; Provisional |
2-362 |
1.28e-51 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 235657 [Multi-domain] Cd Length: 395 Bit Score: 176.54 E-value: 1.28e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 2 SQHVETKLAQIGNRSDEVTGTVSAPI-YLSTA-YRHRGIGESTG--FDYVRTKNPTRQLVEDAIANLENGARGLAFSSGM 77
Cdd:PRK05967 10 KAGINTRLAHDGNDPGDYHGFVNPPVvHASTVlFPDAETMATRGqkYTYGTRGTPTTDALCKAIDALEGSAGTILVPSGL 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 78 AAIQT-IMALFKSGDELIVSSDLYGGTYRLFENEWKKYGLTFHYDDFSDEDCLRSKITPNTKAVFVETPTNPLMQEADIE 156
Cdd:PRK05967 90 AAVTVpFLGFLSPGDHALIVDSVYYPTRHFCDTMLKRLGVEVEYYDPEIGAGIAKLMRPNTKVVHTEAPGSNTFEMQDIP 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 157 HIARITKEHGLLLIVDNTFYTPVLQRPLELGADIVIHSATKYLGGHNDLLAGlVVVKDERLGEEMFQHQNAIGAVLPPFD 236
Cdd:PRK05967 170 AIAEAAHRHGAIVMMDNTWATPLYFRPLDFGVDISIHAATKYPSGHSDILLG-TVSANEKCWPQLLEAHGTLGLCAGPDD 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 237 SWLLMRGMKTLSLRMRQHQANAQELAAFLEEQEEISDVLYP----------------GKGGMLSFRLQKEEW-----VNP 295
Cdd:PRK05967 249 TYQILRGLRTMGIRLEHHRKSALEIARWLEGRPDVARVLHPalpsfpgheiwkrdfsGASGIFSFVLAAGPEkgkakAHA 328
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 906392210 296 FLKALKTICFAESLGGVESFitypatQTHMDIPEEIRIANGVCNRLLRFSVGIEHAEDLKEDLKQAL 362
Cdd:PRK05967 329 FLDALEIFGLGYSWGGYESL------ALHVKLGDRTVAKAPYAGPVIRLQIGLEDVPDLKADLERGF 389
|
|
| PRK07050 |
PRK07050 |
cystathionine beta-lyase; Provisional |
34-362 |
1.94e-47 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 180810 [Multi-domain] Cd Length: 394 Bit Score: 165.67 E-value: 1.94e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 34 RHRGIGESTGFDYVRTKNPTRQLVEDAIANLENGARGLAFSSGMAAIQTI-MALFKSGDELIVSSDLYGGTYRLFENEWK 112
Cdd:PRK07050 47 RALDWRQDVQWRYGLHATPTSLALAQRLAEIEGGRHALLQPSGLAAISLVyFGLVKAGDDVLIPDNAYGPNRDHGEWLAR 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 113 KYGLTFHYDDFSDEDCLRSKITPNTKAVFVETPTNPLMQEADIEHIARITKEHGLLLIVDNTFYTPVLQRPLELGADIVI 192
Cdd:PRK07050 127 DFGITVRFYDPLIGAGIADLIQPNTRLIWLEAPGSVTMEVPDVPAITAAARARGVVTAIDNTYSAGLAFKPFEHGVDISV 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 193 HSATKYLGGHNDLLAGLVVVKDERLGEEMFQHQNAIGAVLPPFDSWLLMRGMKTLSLRMRQHQANAQELAAFLEEQEEIS 272
Cdd:PRK07050 207 QALTKYQSGGSDVLMGATITADAELHAKLKLARMRLGIGVSADDCSLVLRGLPSLQVRLAAHDRSALEVAEWLKARPEIA 286
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 273 DVLYP----------------GKGGMLSFRLQKE---EWVNPFLKALKTICFAESLGGVESF-ITYP-ATQTHMDIPEEi 331
Cdd:PRK07050 287 TVLHPalpdcpghafwmrdftGAGGLFSVVFDERyspAQVDAFVEALELFAIGWSWGGACSLaMPYDvASMRTAKWPHR- 365
|
330 340 350
....*....|....*....|....*....|.
gi 906392210 332 riangvcNRLLRFSVGIEHAEDLKEDLKQAL 362
Cdd:PRK07050 366 -------GTLVRLYIGLEDEADLIADLEQAL 389
|
|
| PLN02242 |
PLN02242 |
methionine gamma-lyase |
38-348 |
6.83e-47 |
|
methionine gamma-lyase
Pssm-ID: 215134 Cd Length: 418 Bit Score: 164.94 E-value: 6.83e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 38 IGESTGFD-YVRTKNPTRQLVEDAIANLENGARGLAFSSGMAAI-QTIMALFKSGDELIVSSDLYGGTYRLFENEW-KKY 114
Cdd:PLN02242 61 LGPDRDFYiYSRHFNPTVLNLGRQMAALEGTEAAYCTASGMSAIsSVLLQLCSSGGHVVASNTLYGGTHALLAHFLpRKC 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 115 GLTFHYDDFSDEDCLRSKITPN-TKAVFVETPTNPLMQEADIEHIARITKEHGLLLIVDNTFyTPVLQRPLELGADIVIH 193
Cdd:PLN02242 141 NITTTFVDITDLEAVKKAVVPGkTKVLYFESISNPTLTVADIPELARIAHEKGVTVVVDNTF-APMVLSPARLGADVVVH 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 194 SATKYLGGHNDLLAGLVVVKDERLGEEMFQHQNAI---GAVLPPFDSWLLMRGMKTLSLRMRQHQANAQELAAFLEEQEe 270
Cdd:PLN02242 220 SISKFISGGADIIAGAVCGPAELVNSMMDLHHGALmllGPTMNPKVAFELSERLPHLSLRMKEHCRRAMEYAKRMKELG- 298
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 271 iSDVLYPG-------------------KGGMLSFRLQKEEWVNPFLKALKTIC----FAESLGGVESFITYPATQTHMDI 327
Cdd:PLN02242 299 -LKVIYPGledhpqhallksmankgygFGGLLCLDMDTEERANRLMRYLQNSTqfgfMAVSLGYYETLMSCSGSSTSSEL 377
|
330 340
....*....|....*....|.
gi 906392210 328 PEEIRIANGVCNRLLRFSVGI 348
Cdd:PLN02242 378 DPEEKAAAGISPGLVRMSVGY 398
|
|
| PRK06702 |
PRK06702 |
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; |
26-369 |
1.73e-46 |
|
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase;
Pssm-ID: 102505 [Multi-domain] Cd Length: 432 Bit Score: 164.07 E-value: 1.73e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 26 PIYLSTAYRHRGIG--------ESTGFDYVRTKNPTRQLVEDAIANLENGARGLAFSSGMAAIQ-TIMALFKSGDELIVS 96
Cdd:PRK06702 27 PLYQSTTYKYDTSDdlaalfnlEAEGYIYTRIGNPTLAAFEQKLAELEGGVGAVATASGQAAIMlAVLNICSSGDHLLCS 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 97 SDLYGGTYRLFENEWKKYGL--TFHYDDFSDEDCLrSKITPNTKAVFVETPTNPLMQEADIEHIARITKEHGLLLIVDNT 174
Cdd:PRK06702 107 STVYGGTFNLFGVSLRKLGIdvTFFNPNLTADEIV-ALANDKTKLVYAESLGNPAMNVLNFKEFSDAAKELEVPFIVDNT 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 175 FYTPVLQRPLELGADIVIHSATKYLGGHNDLLAGLVV---------------------------VKDerLGEEMF----- 222
Cdd:PRK06702 186 LATPYLCQAFEHGANIIVHSTTKYIDGHASSLGGIVIdggnfdwtngkypelvepdpsyhgvsyVQN--FGAAAYivkar 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 223 -QHQNAIGAVLPPFDSWLLMRGMKTLSLRMRQHQANAQELAAFLEEQEEISDVLYP-----------------GKGGMLS 284
Cdd:PRK06702 264 vQLLRDYGNCMSPFNAYISNIGLETLHLRMERHSENALAVAKWLADHERIEWVNYPgldsnenyslaqkylkkGASGVLT 343
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 285 FRLQKE-EWVNPFLKALKTICFAESLGGVESFITYPATQTHMDIPEEIRIANGVCNRLLRFSVGIEHAEDLKEDLKQALC 363
Cdd:PRK06702 344 FGIKGGlEAAKEFIANVKLATLVTHVADARTCVIHPASTTHRQLSAEDQRLAGVTSDLIRLSVGIEDVSDIIADLEAALV 423
|
....*.
gi 906392210 364 QVKEGA 369
Cdd:PRK06702 424 GGKQHA 429
|
|
| PRK08114 |
PRK08114 |
cystathionine beta-lyase; Provisional |
2-359 |
1.03e-44 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 181231 [Multi-domain] Cd Length: 395 Bit Score: 158.33 E-value: 1.03e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 2 SQHVETKLAQIGnRSDEVT-GTVSAPIYLST------------AYRHRGIGEstgFDYVRTKNPTRQLVEDAIANLENGA 68
Cdd:PRK08114 3 DKKLDTQLVNAG-RSKKYTqGSVNSVIQRASslvfdsveakkhATRNRANGE---LFYGRRGTLTHFSLQEAMCELEGGA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 69 RGLAFSSGMAAI-QTIMALFKSGDELIVSSDLYGGTYRLFENEWKKYGL-TFHYDDFSDEDcLRSKITPNTKAVFVETPT 146
Cdd:PRK08114 79 GCALYPCGAAAVaNAILAFVEQGDHVLMTGTAYEPTQDFCSKILSKLGVtTTWFDPLIGAD-IAKLIQPNTKVVFLESPG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 147 NPLMQEADIEHIARITKEHG--LLLIVDNTFYTPVLQRPLELGADIVIHSATKYLGGHNDLLAGlVVVKDERLGEEMFQH 224
Cdd:PRK08114 158 SITMEVHDVPAIVAAVRSVNpdAVIMIDNTWAAGVLFKALDFGIDISIQAGTKYLVGHSDAMIG-TAVANARCWEQLREN 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 225 QNAIGAVLPPFDSWLLMRGMKTLSLRMRQHQANAQELAAFLEEQEEISDVLYP----------------GKGGMLSFRLQ 288
Cdd:PRK08114 237 SYLMGQMVDADTAYMTSRGLRTLGVRLRQHEESSLKVAEWLAEHPEVARVNHPalpgckghefwkrdftGSSGLFSFVLK 316
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 906392210 289 KE---EWVNPFLKALKTICFAESLGGVESFITypATQthmdiPEE---IRIANGV--CNRLLRFSVGIEHAEDLKEDLK 359
Cdd:PRK08114 317 KKltdEQLANYLDNFSLFSMAYSWGGFESLIL--ANQ-----PEEiaaIRPAGEVdfTGTLIRLHIGLEDVDDLIADLA 388
|
|
| AAT_like |
cd00609 |
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
59-285 |
1.85e-17 |
|
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.
Pssm-ID: 99734 [Multi-domain] Cd Length: 350 Bit Score: 82.39 E-value: 1.85e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 59 DAIANLENGARGLA--------FSSGMAAIQTIM-ALFKSGDELIVSS---DLYGGTYRLFENEWKKYGLTFHYDDFSDE 126
Cdd:cd00609 43 EAIAEWLGRRGGVDvppeeivvTNGAQEALSLLLrALLNPGDEVLVPDptyPGYEAAARLAGAEVVPVPLDEEGGFLLDL 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 127 DCLRSKITPNTKAVFVETPTNP---LMQEADIEHIARITKEHGLLLIVDNTF----YTPVLQRPLELGAD----IVIHSA 195
Cdd:cd00609 123 ELLEAAKTPKTKLLYLNNPNNPtgaVLSEEELEELAELAKKHGILIISDEAYaelvYDGEPPPALALLDAyervIVLRSF 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 196 TKYLGghndlLAGL----VVVKDERLGEEMFQHQNAIGAVLPPFDSWLLMRGMKTLS---LRMRQH-QANAQELAAFLee 267
Cdd:cd00609 203 SKTFG-----LPGLrigyLIAPPEELLERLKKLLPYTTSGPSTLSQAAAAAALDDGEehlEELRERyRRRRDALLEAL-- 275
|
250
....*....|....*...
gi 906392210 268 QEEISDVLYPGKGGMLSF 285
Cdd:cd00609 276 KELGPLVVVKPSGGFFLW 293
|
|
| AAT_I |
cd01494 |
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ... |
69-201 |
2.32e-13 |
|
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).
Pssm-ID: 99742 [Multi-domain] Cd Length: 170 Bit Score: 67.41 E-value: 2.32e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 69 RGLAFSSGMAAIQT-IMALFKSGDELIVSSDLYGGTYRLFENewKKYGLTFHYDDFSDEDCL-------RSKITPNTKAV 140
Cdd:cd01494 19 KAVFVPSGTGANEAaLLALLGPGDEVIVDANGHGSRYWVAAE--LAGAKPVPVPVDDAGYGGldvaileELKAKPNVALI 96
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 906392210 141 FVETPTNPLMQEADIEHIARITKEHGLLLIVDNT---FYTPVLQ-RPLELGADIVIHSATKYLGG 201
Cdd:cd01494 97 VITPNTTSGGVLVPLKEIRKIAKEYGILLLVDAAsagGASPAPGvLIPEGGADVVTFSLHKNLGG 161
|
|
| AspB |
COG0436 |
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; ... |
71-214 |
3.89e-11 |
|
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; Aspartate/methionine/tyrosine aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 440205 [Multi-domain] Cd Length: 387 Bit Score: 64.00 E-value: 3.89e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 71 LAFSSGMAAIQ-TIMALFKSGDELIV----------SSDLYGGTYR----LFENEWKKygltfhyddfsDEDCLRSKITP 135
Cdd:COG0436 94 LVTNGAKEALAlALLALLNPGDEVLVpdpgypsyraAVRLAGGKPVpvplDEENGFLP-----------DPEALEAAITP 162
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 136 NTKAVFVETPTNP---LMQEADIEHIARITKEHGLLLIVDN-----TF----YTPVLQRPlelGAD---IVIHSATK--- 197
Cdd:COG0436 163 RTKAIVLNSPNNPtgaVYSREELEALAELAREHDLLVISDEiyeelVYdgaeHVSILSLP---GLKdrtIVINSFSKsya 239
|
170 180
....*....|....*....|....
gi 906392210 198 -------YLGGHNDLLAGLVVVKD 214
Cdd:COG0436 240 mtgwrigYAVGPPELIAALLKLQS 263
|
|
| HisC |
COG0079 |
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid ... |
78-218 |
1.00e-10 |
|
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid transport and metabolism]; Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 439849 [Multi-domain] Cd Length: 341 Bit Score: 62.46 E-value: 1.00e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 78 AAIQTIM-ALFKSGDELIVSSdlygGTYRLFENEWKKYGLTFHY----DDFS-DEDCLRSKITPNTKAVFVETPTNP--- 148
Cdd:COG0079 76 ELIQLLArAFLGPGDEVLVPE----PTFSEYPIAARAAGAEVVEvpldEDFSlDLDALLAAITERTDLVFLCNPNNPtgt 151
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 906392210 149 LMQEADIEHIARITKEHGlLLIVDNTF--YTPVLQRPLELGAD----IVIHSATKYLGghndlLAGLvvvkdeRLG 218
Cdd:COG0079 152 LLPREELEALLEALPADG-LVVVDEAYaeFVPEEDSALPLLARypnlVVLRTFSKAYG-----LAGL------RLG 215
|
|
| Aminotran_1_2 |
pfam00155 |
Aminotransferase class I and II; |
69-172 |
3.93e-08 |
|
Aminotransferase class I and II;
Pssm-ID: 395103 [Multi-domain] Cd Length: 351 Bit Score: 54.62 E-value: 3.93e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 69 RGLAFSSGM-AAIQTIMALFKSGDELIVSSDLYggtYRLFENEWKKYGLTFHY------DDFS-DEDCLRSKITPNTKAV 140
Cdd:pfam00155 64 AAVVFGSGAgANIEALIFLLANPGDAILVPAPT---YASYIRIARLAGGEVVRyplydsNDFHlDFDALEAALKEKPKVV 140
|
90 100 110
....*....|....*....|....*....|....*
gi 906392210 141 FVETPTNP---LMQEADIEHIARITKEHGLLLIVD 172
Cdd:pfam00155 141 LHTSPHNPtgtVATLEELEKLLDLAKEHNILLLVD 175
|
|
| PLN00175 |
PLN00175 |
aminotransferase family protein; Provisional |
82-175 |
4.66e-08 |
|
aminotransferase family protein; Provisional
Pssm-ID: 215089 [Multi-domain] Cd Length: 413 Bit Score: 54.49 E-value: 4.66e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 82 TIMALFKSGDELIVSS---DLYGGTYRLFENEWKkyGLTFHYDDFS-DEDCLRSKITPNTKAVFVETPTNP---LMQEAD 154
Cdd:PLN00175 131 TILGLINPGDEVILFApfyDSYEATLSMAGAKIK--TVTLRPPDFAvPEDELKAAFTSKTRAILINTPHNPtgkMFTREE 208
|
90 100
....*....|....*....|.
gi 906392210 155 IEHIARITKEHGLLLIVDNTF 175
Cdd:PLN00175 209 LELIASLCKENDVLAFTDEVY 229
|
|
| DegT_DnrJ_EryC1 |
pfam01041 |
DegT/DnrJ/EryC1/StrS aminotransferase family; The members of this family are probably all ... |
49-256 |
7.63e-08 |
|
DegT/DnrJ/EryC1/StrS aminotransferase family; The members of this family are probably all pyridoxal-phosphate-dependent aminotransferase enzymes with a variety of molecular functions. The family includes StsA, StsC and StsS. The aminotransferase activity was demonstrated for purified StsC protein as the L-glutamine:scyllo-inosose aminotransferase EC:2.6.1.50, which catalyzes the first amino transfer in the biosynthesis of the streptidine subunit of streptomycin.
Pssm-ID: 395827 Cd Length: 360 Bit Score: 53.44 E-value: 7.63e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 49 TKNPTRQLVEDAIANLENGARGLAFSSGMAAIQTIMALF--KSGDELIVSSDLYGGTyrlfENEWKKYGLT-----FHYD 121
Cdd:pfam01041 21 TTGPYVREFERAFAAYLGVKHAIAVSSGTAALHLALRALgvGPGDEVITPSFTFVAT----ANAALRLGAKpvfvdIDPD 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 122 DFS-DEDCLRSKITPNTKAVFvetPTNPLMQEADIEHIARITKEHGLLLIVD--NTFYTPVLQRPLELGADIVIHS--AT 196
Cdd:pfam01041 97 TYNiDPEAIEAAITPRTKAII---PVHLYGQPADMDAIRAIAARHGLPVIEDaaHALGATYQGKKVGTLGDAATFSfhPT 173
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 906392210 197 KylgghndLLA----GLVVVKDERLGEEMFQHQNAiGAVLPPFDS-WLLMRGMKTlslRMRQHQA 256
Cdd:pfam01041 174 K-------NLTtgegGAVVTNDPELAEKARVLRNH-GMVRKADKRyWHEVLGYNY---RMTEIQA 227
|
|
| PRK13355 |
PRK13355 |
bifunctional HTH-domain containing protein/aminotransferase; Provisional |
82-172 |
1.05e-07 |
|
bifunctional HTH-domain containing protein/aminotransferase; Provisional
Pssm-ID: 237361 [Multi-domain] Cd Length: 517 Bit Score: 53.59 E-value: 1.05e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 82 TIMALFKSGDELIVSS----------DLYGGT---YRLFE-NEWkkygltfhYDDFSDedcLRSKITPNTKAVFVETPTN 147
Cdd:PRK13355 224 SMSALLDDGDEVLIPSpdyplwtacvNLAGGTavhYRCDEqSEW--------YPDIDD---IRSKITSRTKAIVIINPNN 292
|
90 100
....*....|....*....|....*...
gi 906392210 148 P---LMQEADIEHIARITKEHGLLLIVD 172
Cdd:PRK13355 293 PtgaLYPREVLQQIVDIAREHQLIIFSD 320
|
|
| WecE |
COG0399 |
dTDP-4-amino-4,6-dideoxygalactose transaminase [Cell wall/membrane/envelope biogenesis]; |
58-173 |
1.68e-07 |
|
dTDP-4-amino-4,6-dideoxygalactose transaminase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440168 Cd Length: 364 Bit Score: 52.38 E-value: 1.68e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 58 EDAIANLENGARGLAFSSGMAAIQT-IMAL-FKSGDELIVSSdlyggtyrlfenewkkygLTF----------------- 118
Cdd:COG0399 36 EEEFAAYLGVKHAVAVSSGTAALHLaLRALgIGPGDEVITPA------------------FTFvatanailyvgatpvfv 97
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 906392210 119 --HYDDFS-DEDCLRSKITPNTKAVFvetPTNPLMQEADIEHIARITKEHGLLLIVDN 173
Cdd:COG0399 98 diDPDTYNiDPEALEAAITPRTKAII---PVHLYGQPADMDAIMAIAKKHGLKVIEDA 152
|
|
| PRK00451 |
PRK00451 |
aminomethyl-transferring glycine dehydrogenase subunit GcvPA; |
121-192 |
2.92e-07 |
|
aminomethyl-transferring glycine dehydrogenase subunit GcvPA;
Pssm-ID: 234769 [Multi-domain] Cd Length: 447 Bit Score: 52.06 E-value: 2.92e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 906392210 121 DDFSDEDCLRSKITPNTKAVFVETPtNPLMQEADIEHIARITKEHGLLLIVdntFYTPV----LQRPLELGADIVI 192
Cdd:PRK00451 189 DGVTDLEALEAAVDDDTAAVVVQYP-NFFGVIEDLEEIAEIAHAGGALFIV---GVDPVslglLKPPGEYGADIVV 260
|
|
| PRK09265 |
PRK09265 |
aminotransferase AlaT; Validated |
85-172 |
3.88e-07 |
|
aminotransferase AlaT; Validated
Pssm-ID: 181738 Cd Length: 404 Bit Score: 51.35 E-value: 3.88e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 85 ALFKSGDE-LIVSSD---------LYGGT---YRLFE-NEWkkygltfhyddFSDEDCLRSKITPNTKAVFVETPTNP-- 148
Cdd:PRK09265 114 ALLNNGDEvLVPAPDyplwtaavsLSGGKpvhYLCDEeAGW-----------FPDLDDIRSKITPRTKAIVIINPNNPtg 182
|
90 100
....*....|....*....|....*
gi 906392210 149 -LMQEADIEHIARITKEHGLLLIVD 172
Cdd:PRK09265 183 aVYSKELLEEIVEIARQHNLIIFAD 207
|
|
| AHBA_syn |
cd00616 |
3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal ... |
58-173 |
6.15e-07 |
|
3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary metabolites. Some well studied proteins in this CD are AHBA_synthase, protein product of pleiotropic regulatory gene degT, Arnb aminotransferase and pilin glycosylation protein. The prototype of this family, the AHBA_synthase, is a dimeric PLP dependent enzyme. AHBA_syn is the terminal enzyme of 3-amino-5-hydroxybenzoic acid (AHBA) formation which is involved in the biosynthesis of ansamycin antibiotics, including rifamycin B. Some members of this CD are involved in 4-amino-6-deoxy-monosaccharide D-perosamine synthesis. Perosamine is an important element in the glycosylation of several cell products, such as antibiotics and lipopolysaccharides of gram-positive and gram-negative bacteria. The pilin glycosylation protein encoded by gene pglA, is a galactosyltransferase involved in pilin glycosylation. Additionally, this CD consists of ArnB (PmrH) aminotransferase, a 4-amino-4-deoxy-L-arabinose lipopolysaccharide-modifying enzyme. This CD also consists of several predicted pyridoxal phosphate-dependent enzymes apparently involved in regulation of cell wall biogenesis. The catalytic lysine which is present in all characterized PLP dependent enzymes is replaced by histidine in some members of this CD.
Pssm-ID: 99740 [Multi-domain] Cd Length: 352 Bit Score: 50.62 E-value: 6.15e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 58 EDAIANLeNGAR-GLAFSSGMAAIQTIMALF--KSGDELIVSSdlyggtyrlfenewkkygLTF---------------- 118
Cdd:cd00616 24 EKAFAEY-LGVKyAVAVSSGTAALHLALRALgiGPGDEVIVPS------------------FTFvatanailllgatpvf 84
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 906392210 119 ---HYDDFS-DEDCLRSKITPNTKAVFvetPTNPLMQEADIEHIARITKEHGLLLIVDN 173
Cdd:cd00616 85 vdiDPDTYNiDPELIEAAITPRTKAII---PVHLYGNPADMDAIMAIAKRHGLPVIEDA 140
|
|
| PRK05764 |
PRK05764 |
aspartate aminotransferase; Provisional |
82-172 |
6.67e-07 |
|
aspartate aminotransferase; Provisional
Pssm-ID: 235596 Cd Length: 393 Bit Score: 50.89 E-value: 6.67e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 82 TIMALFKSGDELIVSS----------DLYGGTYRLFEnewkkyglTFHYDDFS-DEDCLRSKITPNTKAVFVETPTNP-- 148
Cdd:PRK05764 107 AFMALLDPGDEVIIPApywvsypemvKLAGGVPVFVP--------TGEENGFKlTVEQLEAAITPKTKALILNSPSNPtg 178
|
90 100
....*....|....*....|....*
gi 906392210 149 -LMQEADIEHIARITKEHGLLLIVD 172
Cdd:PRK05764 179 aVYSPEELEAIADVAVEHDIWVLSD 203
|
|
| PRK08363 |
PRK08363 |
alanine aminotransferase; Validated |
79-175 |
1.39e-06 |
|
alanine aminotransferase; Validated
Pssm-ID: 181402 Cd Length: 398 Bit Score: 49.81 E-value: 1.39e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 79 AIQTIM-ALFKSGDELIV---SSDLYGGTYRLFENEWKKYgLTFHYDDFS-DEDCLRSKITPNTKAVFVETPTNP---LM 150
Cdd:PRK08363 105 ALQLIFgALLDPGDEILIpgpSYPPYTGLVKFYGGVPVEY-RTIEEEGWQpDIDDIRKKITEKTKAIAVINPNNPtgaLY 183
|
90 100
....*....|....*....|....*
gi 906392210 151 QEADIEHIARITKEHGLLLIVDNTF 175
Cdd:PRK08363 184 EKKTLKEILDIAGEHDLPVISDEIY 208
|
|
| PRK12414 |
PRK12414 |
putative aminotransferase; Provisional |
74-175 |
1.76e-06 |
|
putative aminotransferase; Provisional
Pssm-ID: 183514 Cd Length: 384 Bit Score: 49.40 E-value: 1.76e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 74 SSGMAAiqTIMALFKSGDELIV---SSDLYGGTYRLfeNEWKKYGLTFHYDDFS-DEDCLRSKITPNTKAVFVETPTNP- 148
Cdd:PRK12414 100 SEGLYA--AISALVHPGDEVIYfepSFDSYAPIVRL--QGATPVAIKLSPEDFRvNWDEVAAAITPRTRMIIVNTPHNPs 175
|
90 100
....*....|....*....|....*....
gi 906392210 149 --LMQEADIEHIARITKEHGLLLIVDNTF 175
Cdd:PRK12414 176 atVFSAADLARLAQLTRNTDIVILSDEVY 204
|
|
| PRK06348 |
PRK06348 |
pyridoxal phosphate-dependent aminotransferase; |
76-178 |
1.98e-06 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180537 Cd Length: 384 Bit Score: 49.33 E-value: 1.98e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 76 GM-AAIQTIMalfKSGDELIVSS----------DLYGGTYRLFEnewkkyglTFHYDDFS-DEDCLRSKITPNTKAVFVE 143
Cdd:PRK06348 101 GMyLALQSIL---DPGDEVIIHEpyftpykdqiEMVGGKPIILE--------TYEEDGFQiNVKKLEALITSKTKAIILN 169
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 906392210 144 TPTNP---LMQEADIEHIARITKEHGLLLIVDN-----TFYTP 178
Cdd:PRK06348 170 SPNNPtgaVFSKETLEEIAKIAIEYDLFIISDEvydgfSFYED 212
|
|
| PRK07550 |
PRK07550 |
aminotransferase; |
68-239 |
2.93e-06 |
|
aminotransferase;
Pssm-ID: 181026 [Multi-domain] Cd Length: 386 Bit Score: 48.80 E-value: 2.93e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 68 ARGLAFSSG--MAAIQTIMALFKSGDELIVSSDLYggtyrlFENE-W-KKYGLTFHYDDFSDEDCL-------RSKITPN 136
Cdd:PRK07550 90 PEQVHITSGcnQAFWAAMVTLAGAGDEVILPLPWY------FNHKmWlDMLGIRPVYLPCDEGPGLlpdpaaaEALITPR 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 137 TKAVFVETPTNP--------LMQEadiehIARITKEHGLLLIVDNTF--YTPVLQRPLELGAD-------IVIHSATK-Y 198
Cdd:PRK07550 164 TRAIALVTPNNPtgvvyppeLLHE-----LYDLARRHGIALILDETYrdFDSGGGAPHDLFADpdwddtlVHLYSFSKsY 238
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 906392210 199 -LGGHNdllAGLVVVKDERLGE-EMFQH----------QNAIGAVLPPFDSWL 239
Cdd:PRK07550 239 aLTGHR---VGAVVASPARIAEiEKFMDtvaicaprigQIAVAWGLPNLADWR 288
|
|
| SelA |
COG1921 |
Seryl-tRNA(Sec) selenium transferase [Translation, ribosomal structure and biogenesis]; |
133-271 |
6.02e-06 |
|
Seryl-tRNA(Sec) selenium transferase [Translation, ribosomal structure and biogenesis];
Pssm-ID: 441524 Cd Length: 399 Bit Score: 47.81 E-value: 6.02e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 133 ITPNTKAV------------FVETPtnplmqeaDIEHIARITKEHGLLLIVD------------NTFYTPVLQRPLELGA 188
Cdd:COG1921 151 ITENTAALlkvhtsnyrivgFTEEV--------SLAELAELAHEHGLPVIVDlgsgslvdlskyGLPHEPTVQEYLAAGA 222
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 189 DIVIHSATKYLGGHNdllAGLVVVKDErLGEEMFQHQnaigavlppfdswlLMRGMK----TLS-----LRMRQHQANAQ 259
Cdd:COG1921 223 DLVTFSGDKLLGGPQ---AGIIVGKKE-LIERIKKNP--------------LGRALRvdkeTLAaleatLRLYLDPEKAA 284
|
170
....*....|....*.
gi 906392210 260 E----LAAFLEEQEEI 271
Cdd:COG1921 285 EeiptLRMLTRPQEEL 300
|
|
| PucG |
COG0075 |
Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism ... |
74-172 |
9.32e-06 |
|
Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG [Amino acid transport and metabolism, Nucleotide transport and metabolism]; Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG is part of the Pathway/BioSystem: Serine biosynthesis
Pssm-ID: 439845 [Multi-domain] Cd Length: 376 Bit Score: 47.01 E-value: 9.32e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 74 SSGMAAIQT-IMALFKSGDELIVSS------------DLYGGTYRLFENEWkkyGLTFHYDDFsdEDCLRSKitPNTKAV 140
Cdd:COG0075 57 GSGTGAMEAaLANLVSPGDKVLVLVngafgerwaeiaERYGAEVVVLEVPW---GEAVDPEEV--EEALAAD--PDIKAV 129
|
90 100 110
....*....|....*....|....*....|....*...
gi 906392210 141 FV---ETPT---NPlmqeadIEHIARITKEHGLLLIVD 172
Cdd:COG0075 130 AVvhnETSTgvlNP------LEEIGALAKEHGALLIVD 161
|
|
| GDC-P |
cd00613 |
Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine ... |
125-215 |
1.07e-05 |
|
Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1.2.10 (GDC) also annotated as glycine cleavage system or glycine synthase. GDC consists of four proteins P, H, L and T. The reaction catalysed by this protein is: Glycine + lipoylprotein <=> S-aminomethyldihydrolipoylprotein + CO2. Alpha-beta-type dimers associate to form an alpha(2)beta(2) tetramer, where the alpha- and beta-subunits are structurally similar and appear to have arisen by gene duplication and subsequent divergence with a loss of one active site. The members of this CD are widely dispersed among all three forms of cellular life.
Pssm-ID: 99737 [Multi-domain] Cd Length: 398 Bit Score: 46.84 E-value: 1.07e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 125 DEDCLRSKITPNTKAVFVETP-TNPLMqEADIEHIARITKEHGLLLIV--DNTFYTpVLQRPLELGADIVIHSATK---- 197
Cdd:cd00613 148 DLEALKEEVSEEVAALMVQYPnTLGVF-EDLIKEIADIAHSAGALVYVdgDNLNLT-GLKPPGEYGADIVVGNLQKtgvp 225
|
90 100
....*....|....*....|
gi 906392210 198 --YLGGHndllAGLVVVKDE 215
Cdd:cd00613 226 hgGGGPG----AGFFAVKKE 241
|
|
| PRK06836 |
PRK06836 |
pyridoxal phosphate-dependent aminotransferase; |
57-172 |
1.26e-05 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180720 Cd Length: 394 Bit Score: 46.72 E-value: 1.26e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 57 VEDAIANLENGARGLAFS-------SGMA-AIQTIM-ALFKSGDELIVSSDlYGGTYRLF-ENewkkYGLTFHY-----D 121
Cdd:PRK06836 78 VREAIAESLNRRFGTPLTadhivmtCGAAgALNVALkAILNPGDEVIVFAP-YFVEYRFYvDN----HGGKLVVvptdtD 152
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 906392210 122 DFS-DEDCLRSKITPNTKAVFVETPTNP---LMQEADIEHIARI----TKEHG--LLLIVD 172
Cdd:PRK06836 153 TFQpDLDALEAAITPKTKAVIINSPNNPtgvVYSEETLKALAALleekSKEYGrpIYLISD 213
|
|
| PRK07568 |
PRK07568 |
pyridoxal phosphate-dependent aminotransferase; |
79-172 |
2.37e-05 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 181036 Cd Length: 397 Bit Score: 46.00 E-value: 2.37e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 79 AIQ-TIMALFKSGDELIVSSDLYGgTYRLFEnewKKYGLT-----------FH---YDDFsdedclRSKITPNTKAVFVE 143
Cdd:PRK07568 100 AILfAMMAICDPGDEILVPEPFYA-NYNGFA---TSAGVKivpvttkieegFHlpsKEEI------EKLITPKTKAILIS 169
|
90 100 110
....*....|....*....|....*....|..
gi 906392210 144 TPTNP---LMQEADIEHIARITKEHGLLLIVD 172
Cdd:PRK07568 170 NPGNPtgvVYTKEELEMLAEIAKKHDLFLISD 201
|
|
| PRK06225 |
PRK06225 |
pyridoxal phosphate-dependent aminotransferase; |
54-283 |
2.43e-05 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235749 [Multi-domain] Cd Length: 380 Bit Score: 45.90 E-value: 2.43e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 54 RQLVEDAIANLE-NGARGLAFSSGMAAIQTIM-ALFKSGDELIVSSDlyggTYRLFENEWKKYGLTFHYDDFSDEDC--- 128
Cdd:PRK06225 69 PELRELILKDLGlDDDEALITAGATESLYLVMrAFLSPGDNAVTPDP----GYLIIDNFASRFGAEVIEVPIYSEECnyk 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 129 -----LRSKITPNTKAVFVETPTNPL---MQEADIEHIARITKEHGLLLIVDNTFYTPVLQRPLELGAD----IVIHSAT 196
Cdd:PRK06225 145 ltpelVKENMDENTRLIYLIDPLNPLgssYTEEEIKEFAEIARDNDAFLLHDCTYRDFAREHTLAAEYApehtVTSYSFS 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 197 KYLG----------GHNDLLAGLVVVKDERLGEEMFQHQNAIGAvLPPFDSWllmrgMKTLSLRMRQHQANAQELAaflE 266
Cdd:PRK06225 225 KIFGmaglrigavvATPDLIEVVKSIVINDLGTNVIAQEAAIAG-LKVKDEW-----IDRIRRTTFKNQKLIKEAV---D 295
|
250
....*....|....*..
gi 906392210 267 EQEEISDVLYPGKGGML 283
Cdd:PRK06225 296 EIEGVFLPVYPSHGNMM 312
|
|
| PRK06108 |
PRK06108 |
pyridoxal phosphate-dependent aminotransferase; |
74-172 |
3.95e-05 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180404 Cd Length: 382 Bit Score: 45.32 E-value: 3.95e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 74 SSGMAAIQ-TIMALFKSGDELI----------------------VSSDLYGGTYRLfenewkkygltfhyddfsDEDCLR 130
Cdd:PRK06108 91 SSGVQALMlAAQALVGPGDEVVavtplwpnlvaapkilgarvvcVPLDFGGGGWTL------------------DLDRLL 152
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 906392210 131 SKITPNTKAVFVETPTNPL---MQEADIEHIARITKEHGLLLIVD 172
Cdd:PRK06108 153 AAITPRTRALFINSPNNPTgwtASRDDLRAILAHCRRHGLWIVAD 197
|
|
| PRK08912 |
PRK08912 |
aminotransferase; |
82-172 |
6.45e-05 |
|
aminotransferase;
Pssm-ID: 181580 Cd Length: 387 Bit Score: 44.58 E-value: 6.45e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 82 TIMALFKSGDELIVSSDLY----------GGTYRLFENEWKKYGLtfhyddfsDEDCLRSKITPNTKAVFVETPTNP--- 148
Cdd:PRK08912 103 ALLALVEPGDEVVLFQPLYdaylplirraGGVPRLVRLEPPHWRL--------PRAALAAAFSPRTKAVLLNNPLNPagk 174
|
90 100
....*....|....*....|....
gi 906392210 149 LMQEADIEHIARITKEHGLLLIVD 172
Cdd:PRK08912 175 VFPREELALLAEFCQRHDAVAICD 198
|
|
| ArgD |
COG4992 |
Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase [Amino acid transport and ... |
118-172 |
7.73e-05 |
|
Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase [Amino acid transport and metabolism]; Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase is part of the Pathway/BioSystem: Arginine biosynthesis
Pssm-ID: 444016 [Multi-domain] Cd Length: 396 Bit Score: 44.26 E-value: 7.73e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 906392210 118 FHYDDFSDEDCLRSKITPNTKAVFVET---------PTNPLMQEAdiehiARITKEHGLLLIVD 172
Cdd:COG4992 163 FVFVPFNDLEALEAAIDDDTAAVIVEPiqgeggvipPPPGYLKGL-----RELCDEHGALLILD 221
|
|
| Aminotran_5 |
pfam00266 |
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes ... |
55-221 |
8.62e-05 |
|
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes including cysteine desulphurase EC:4.4.1.-.
Pssm-ID: 425567 [Multi-domain] Cd Length: 368 Bit Score: 44.16 E-value: 8.62e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 55 QLVEDA---IANLENG--ARGLAFSSGM-----AAIQTIMALFKSGDELIVSsdlyggtyrlfENE-------W----KK 113
Cdd:pfam00266 43 QAYEEArekVAEFINApsNDEIIFTSGTteainLVALSLGRSLKPGDEIVIT-----------EMEhhanlvpWqelaKR 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 114 YGLTFHY-----DDFSDEDCLRSKITPNTKAVFVETPTNPLMQEADIEHIARITKEHGLLLIVDNTfyTPVLQRPL---E 185
Cdd:pfam00266 112 TGARVRVlpldeDGLLDLDELEKLITPKTKLVAITHVSNVTGTIQPVPEIGKLAHQYGALVLVDAA--QAIGHRPIdvqK 189
|
170 180 190
....*....|....*....|....*....|....*...
gi 906392210 186 LGADIVIHSATKYLG--GhndllAGLVVVKDErLGEEM 221
Cdd:pfam00266 190 LGVDFLAFSGHKLYGptG-----IGVLYGRRD-LLEKM 221
|
|
| PRK02627 |
PRK02627 |
acetylornithine aminotransferase; Provisional |
118-172 |
1.06e-04 |
|
acetylornithine aminotransferase; Provisional
Pssm-ID: 235056 [Multi-domain] Cd Length: 396 Bit Score: 43.97 E-value: 1.06e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 906392210 118 FHYDDFSDEDCLRSKITPNTKAVFVEtptnPLMQE-----ADIEHI---ARITKEHGLLLIVD 172
Cdd:PRK02627 164 FIYVPFNDIEALKAAITDKTAAVMLE----PIQGEggvnpADKEYLqalRELCDENGILLILD 222
|
|
| PRK07682 |
PRK07682 |
aminotransferase; |
129-172 |
1.96e-04 |
|
aminotransferase;
Pssm-ID: 181082 [Multi-domain] Cd Length: 378 Bit Score: 43.18 E-value: 1.96e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 906392210 129 LRSKITPNTKAVFVETPTNP---LMQEADIEHIARITKEHGLLLIVD 172
Cdd:PRK07682 147 IEAAITAKTKAILLCSPNNPtgaVLNKSELEEIAVIVEKHDLIVLSD 193
|
|
| avtA |
PRK09440 |
valine--pyruvate transaminase; Provisional |
132-178 |
2.15e-04 |
|
valine--pyruvate transaminase; Provisional
Pssm-ID: 236517 Cd Length: 416 Bit Score: 42.92 E-value: 2.15e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 906392210 132 KITPNTKAVFVETPTNP---LMQEADIEHIARITKEHGLLLIVDNTFYTP 178
Cdd:PRK09440 175 HIDEDTGAICVSRPTNPtgnVLTDEELEKLDALARQHNIPLLIDNAYGPP 224
|
|
| PRK07324 |
PRK07324 |
transaminase; Validated |
65-172 |
4.81e-04 |
|
transaminase; Validated
Pssm-ID: 235989 Cd Length: 373 Bit Score: 41.85 E-value: 4.81e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 65 ENGARGlafssgmAAIQTIMALFKSGDELIVSSDLYGGTYRLFENewkkYGLTFHY------DDFS-DEDCLRSKITPNT 137
Cdd:PRK07324 86 TNGATG-------ANFLVLYALVEPGDHVISVYPTYQQLYDIPES----LGAEVDYwqlkeeNGWLpDLDELRRLVRPNT 154
|
90 100 110
....*....|....*....|....*....|....*...
gi 906392210 138 KAVFVETPTNP---LMQEADIEHIARITKEHGLLLIVD 172
Cdd:PRK07324 155 KLICINNANNPtgaLMDRAYLEEIVEIARSVDAYVLSD 192
|
|
| argD |
PRK01278 |
acetylornithine transaminase protein; Provisional |
118-172 |
6.83e-04 |
|
acetylornithine transaminase protein; Provisional
Pssm-ID: 179270 [Multi-domain] Cd Length: 389 Bit Score: 41.36 E-value: 6.83e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 906392210 118 FHYDDFSDEDCLRSKITPNTKAVFVE---------TPTNPLMQEadiehIARITKEHGLLLIVD 172
Cdd:PRK01278 157 FDQVPFGDIEALKAAITPNTAAILIEpiqgeggirPAPDEFLKG-----LRQLCDENGLLLIFD 215
|
|
| GcvP1 |
COG0403 |
Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain [Amino acid transport ... |
119-192 |
1.31e-03 |
|
Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain [Amino acid transport and metabolism]; Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain is part of the Pathway/BioSystem: Glycine cleavage
Pssm-ID: 440172 [Multi-domain] Cd Length: 442 Bit Score: 40.40 E-value: 1.31e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 119 HYDDFSDEDCLRSKITPNTKAVFVETPtNPLMQEADIEHIARITKEHGLLLIV--DntfytP----VLQRPLELGADIVI 192
Cdd:COG0403 188 DEDGVTDLEALKALLDDDVAGVLVQYP-NFFGVIEDLRAIAEAAHAAGALVIVaaD-----PlslgLLKPPGELGADIVV 261
|
|
| PLN02855 |
PLN02855 |
Bifunctional selenocysteine lyase/cysteine desulfurase |
38-200 |
1.41e-03 |
|
Bifunctional selenocysteine lyase/cysteine desulfurase
Pssm-ID: 215460 [Multi-domain] Cd Length: 424 Bit Score: 40.50 E-value: 1.41e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 38 IGESTGFDYVRTKNPTrqlveDAIaNLengargLAFSSGMAAIqtimalfKSGDELIVS-----SDLYggtyrlfenEWK 112
Cdd:PLN02855 89 INASTSREIVFTRNAT-----EAI-NL------VAYTWGLANL-------KPGDEVILSvaehhSNIV---------PWQ 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 113 ----KYGLTFHY-----DDFSDEDCLRSKITPNTKAVFVETPTNPLMQEADIEHIARITKEHGLLLIVDNTFYTPvlQRP 183
Cdd:PLN02855 141 lvaqKTGAVLKFvgltpDEVLDVEQLKELLSEKTKLVATHHVSNVLGSILPVEDIVHWAHAVGAKVLVDACQSVP--HMP 218
|
170 180
....*....|....*....|
gi 906392210 184 LE---LGADIVIHSATKYLG 200
Cdd:PLN02855 219 VDvqtLGADFLVASSHKMCG 238
|
|
| SelA |
pfam03841 |
L-seryl-tRNA selenium transferase; |
78-225 |
7.44e-03 |
|
L-seryl-tRNA selenium transferase;
Pssm-ID: 309101 Cd Length: 367 Bit Score: 38.09 E-value: 7.44e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 78 AAIQTIMALFKSGDELIVS-SDLY--GGTYRLFEnEWKKYGLTF---------HYDDFsdedclRSKITPNTKAVFVETP 145
Cdd:pfam03841 73 AAVLLVLNTLAAGKEVIISrGELVeiGGSFRIPD-VMKQAGVKLvevgttnrtHLKDY------EQAINENTALLMKVHT 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 146 TNPLMQ----EADIEHIARITKEHGLLLIVD---------NTF---YTPVLQRPLELGADIVIHSATKYLGGHNdllAGL 209
Cdd:pfam03841 146 SNYRIQgftkEVELAELVELGHEKGLPVYEDlgsgslvdlSQYglpKEPTVQELIAQGVDLVSFSGDKLLGGPQ---AGI 222
|
170
....*....|....*.
gi 906392210 210 VVVKDErLGEEMFQHQ 225
Cdd:pfam03841 223 IVGKKE-LIERIKKNP 237
|
|
| PRK08960 |
PRK08960 |
pyridoxal phosphate-dependent aminotransferase; |
134-222 |
9.99e-03 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 181595 Cd Length: 387 Bit Score: 37.73 E-value: 9.99e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906392210 134 TPNTKAVFVETPTNP---LMQEADIEHIARITKEHGLLLIVDNTFYTPVLQRP----LELGADI-VIHSATKYLGGHNDL 205
Cdd:PRK08960 163 NADTVGALVASPANPtgtLLSRDELAALSQALRARGGHLVVDEIYHGLTYGVDaasvLEVDDDAfVLNSFSKYFGMTGWR 242
|
90 100
....*....|....*....|..
gi 906392210 206 LAGLVVVKD-----ERLGEEMF 222
Cdd:PRK08960 243 LGWLVAPPAavpelEKLAQNLY 264
|
|
| |
