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Conserved domains on  [gi|161783807|ref|NP_001104571|]
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CB1 cannabinoid receptor-interacting protein 1 isoform CRIP1b [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CNRIP1 super family cl20916
CB1 cannabinoid receptor-interacting protein 1; This family of proteins interacts with ...
 4-110 1.83e-55

CB1 cannabinoid receptor-interacting protein 1; This family of proteins interacts with cannabinoid receptor 1 (CNR1) and attenuates CNR1-mediated tonic inhibition of voltage-gated calcium channels.


The actual alignment was detected with superfamily member pfam15043:

Pssm-ID: 464465  Cd Length: 152  Bit Score: 169.80  E-value: 1.83e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161783807    4 LPGLVRLSIALRIQPNDGPVFYKVDGQRFGQNRTIKLLTGSSYKVEVKIKPStLQVENISIGGVLVPLELKSKepDGDRV 83
Cdd:pfam15043   1 SPGIFKITLSLRIQPNDGPVFFKVDGERFGQERTIKLLTDSKYKVEITIKPA-LELTSLSIGGVSLELEEKSR--DEEAV 77

                          90       100
                  ....*....|....*....|....*..
gi 161783807   84 VYTGTYDTEGVTPTKSGERQPIQITMP 110
Cdd:pfam15043  78 VYSGEWSTEGVAVSKSGDRQPVQISMQ 104
 
Name Accession Description Interval E-value
CNRIP1 pfam15043
CB1 cannabinoid receptor-interacting protein 1; This family of proteins interacts with ...
 4-110 1.83e-55

CB1 cannabinoid receptor-interacting protein 1; This family of proteins interacts with cannabinoid receptor 1 (CNR1) and attenuates CNR1-mediated tonic inhibition of voltage-gated calcium channels.


Pssm-ID: 464465  Cd Length: 152  Bit Score: 169.80  E-value: 1.83e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161783807    4 LPGLVRLSIALRIQPNDGPVFYKVDGQRFGQNRTIKLLTGSSYKVEVKIKPStLQVENISIGGVLVPLELKSKepDGDRV 83
Cdd:pfam15043   1 SPGIFKITLSLRIQPNDGPVFFKVDGERFGQERTIKLLTDSKYKVEITIKPA-LELTSLSIGGVSLELEEKSR--DEEAV 77

                          90       100
                  ....*....|....*....|....*..
gi 161783807   84 VYTGTYDTEGVTPTKSGERQPIQITMP 110
Cdd:pfam15043  78 VYSGEWSTEGVAVSKSGDRQPVQISMQ 104
 
Name Accession Description Interval E-value
CNRIP1 pfam15043
CB1 cannabinoid receptor-interacting protein 1; This family of proteins interacts with ...
 4-110 1.83e-55

CB1 cannabinoid receptor-interacting protein 1; This family of proteins interacts with cannabinoid receptor 1 (CNR1) and attenuates CNR1-mediated tonic inhibition of voltage-gated calcium channels.


Pssm-ID: 464465  Cd Length: 152  Bit Score: 169.80  E-value: 1.83e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161783807    4 LPGLVRLSIALRIQPNDGPVFYKVDGQRFGQNRTIKLLTGSSYKVEVKIKPStLQVENISIGGVLVPLELKSKepDGDRV 83
Cdd:pfam15043   1 SPGIFKITLSLRIQPNDGPVFFKVDGERFGQERTIKLLTDSKYKVEITIKPA-LELTSLSIGGVSLELEEKSR--DEEAV 77

                          90       100
                  ....*....|....*....|....*..
gi 161783807   84 VYTGTYDTEGVTPTKSGERQPIQITMP 110
Cdd:pfam15043  78 VYSGEWSTEGVAVSKSGDRQPVQISMQ 104
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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