NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|284520904|ref|NP_001165339|]
View 

transmembrane protein 200B [Homo sapiens]

Protein Classification

TMEM200 family protein( domain architecture ID 8052)

TMEM200 family protein is a DUF2371 domain-containing protein; similar to Homo sapiens transmembrane protein 200B

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
DUF2371 super family cl10871
Uncharacterized conserved protein (DUF2371); This is a family of proteins conserved from ...
 50-147 5.86e-28

Uncharacterized conserved protein (DUF2371); This is a family of proteins conserved from nematodes to humans. The function is not known.


The actual alignment was detected with superfamily member pfam10177:

Pssm-ID: 462979  Cd Length: 141  Bit Score: 105.48  E-value: 5.86e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 284520904   50 SPSGAFAALGALVVLVGMGIAVAGYWPHRAGAPGSRA---ANASSPQMSELRREGRGGGRAHGPHERLRLLGPVIMGVGL 126
Cdd:pfam10177  38 SPSGFFALLGILVLLVGIAMAVLGYWPHEVAQLGSRNnnsSNSTAEMSRDHSGFLARFLEQYLHSDKMKVFGPLIMGIGI 117

                          90       100
                  ....*....|....*....|.
gi 284520904  127 FVFICANTLLYENRDLETRRL 147
Cdd:pfam10177 118 FLFICANAVLHENRDKETKII 138
 
Name Accession Description Interval E-value
DUF2371 pfam10177
Uncharacterized conserved protein (DUF2371); This is a family of proteins conserved from ...
 50-147 5.86e-28

Uncharacterized conserved protein (DUF2371); This is a family of proteins conserved from nematodes to humans. The function is not known.


Pssm-ID: 462979  Cd Length: 141  Bit Score: 105.48  E-value: 5.86e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 284520904   50 SPSGAFAALGALVVLVGMGIAVAGYWPHRAGAPGSRA---ANASSPQMSELRREGRGGGRAHGPHERLRLLGPVIMGVGL 126
Cdd:pfam10177  38 SPSGFFALLGILVLLVGIAMAVLGYWPHEVAQLGSRNnnsSNSTAEMSRDHSGFLARFLEQYLHSDKMKVFGPLIMGIGI 117

                          90       100
                  ....*....|....*....|.
gi 284520904  127 FVFICANTLLYENRDLETRRL 147
Cdd:pfam10177 118 FLFICANAVLHENRDKETKII 138
 
Name Accession Description Interval E-value
DUF2371 pfam10177
Uncharacterized conserved protein (DUF2371); This is a family of proteins conserved from ...
 50-147 5.86e-28

Uncharacterized conserved protein (DUF2371); This is a family of proteins conserved from nematodes to humans. The function is not known.


Pssm-ID: 462979  Cd Length: 141  Bit Score: 105.48  E-value: 5.86e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 284520904   50 SPSGAFAALGALVVLVGMGIAVAGYWPHRAGAPGSRA---ANASSPQMSELRREGRGGGRAHGPHERLRLLGPVIMGVGL 126
Cdd:pfam10177  38 SPSGFFALLGILVLLVGIAMAVLGYWPHEVAQLGSRNnnsSNSTAEMSRDHSGFLARFLEQYLHSDKMKVFGPLIMGIGI 117

                          90       100
                  ....*....|....*....|.
gi 284520904  127 FVFICANTLLYENRDLETRRL 147
Cdd:pfam10177 118 FLFICANAVLHENRDKETKII 138
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH