interferon regulatory factor 6 isoform 2 [Homo sapiens]
IRF-3 domain-containing protein( domain architecture ID 10564200)
IRF-3 domain-containing protein
List of domain hits
Name | Accession | Description | Interval | E-value | ||||
IRF-3 | pfam10401 | Interferon-regulatory factor 3; This is the interferon-regulatory factor 3 chain of the ... |
128-312 | 1.78e-89 | ||||
Interferon-regulatory factor 3; This is the interferon-regulatory factor 3 chain of the hetero-dimeric structure which also contains the shorter chain CREB-binding protein. These two subunits make up the DRAF1 (double-stranded RNA-activated factor 1). Viral dsRNA produced during viral transcription or replication leads to the activation of DRAF1. The DNA-binding specificity of DRAF1 correlates with transcriptional induction of ISG (interferon-alpha,beta-stimulated gene). IRF-3 preexists in the cytoplasm of uninfected cells and translocates to the nucleus following viral infection. Translocation of IRF-3 is accompanied by an increase in serine and threonine phosphorylation, and association with the CREB coactivator occurs only after infection. : Pssm-ID: 463076 Cd Length: 180 Bit Score: 266.82 E-value: 1.78e-89
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Name | Accession | Description | Interval | E-value | ||||
IRF-3 | pfam10401 | Interferon-regulatory factor 3; This is the interferon-regulatory factor 3 chain of the ... |
128-312 | 1.78e-89 | ||||
Interferon-regulatory factor 3; This is the interferon-regulatory factor 3 chain of the hetero-dimeric structure which also contains the shorter chain CREB-binding protein. These two subunits make up the DRAF1 (double-stranded RNA-activated factor 1). Viral dsRNA produced during viral transcription or replication leads to the activation of DRAF1. The DNA-binding specificity of DRAF1 correlates with transcriptional induction of ISG (interferon-alpha,beta-stimulated gene). IRF-3 preexists in the cytoplasm of uninfected cells and translocates to the nucleus following viral infection. Translocation of IRF-3 is accompanied by an increase in serine and threonine phosphorylation, and association with the CREB coactivator occurs only after infection. Pssm-ID: 463076 Cd Length: 180 Bit Score: 266.82 E-value: 1.78e-89
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Name | Accession | Description | Interval | E-value | ||||
IRF-3 | pfam10401 | Interferon-regulatory factor 3; This is the interferon-regulatory factor 3 chain of the ... |
128-312 | 1.78e-89 | ||||
Interferon-regulatory factor 3; This is the interferon-regulatory factor 3 chain of the hetero-dimeric structure which also contains the shorter chain CREB-binding protein. These two subunits make up the DRAF1 (double-stranded RNA-activated factor 1). Viral dsRNA produced during viral transcription or replication leads to the activation of DRAF1. The DNA-binding specificity of DRAF1 correlates with transcriptional induction of ISG (interferon-alpha,beta-stimulated gene). IRF-3 preexists in the cytoplasm of uninfected cells and translocates to the nucleus following viral infection. Translocation of IRF-3 is accompanied by an increase in serine and threonine phosphorylation, and association with the CREB coactivator occurs only after infection. Pssm-ID: 463076 Cd Length: 180 Bit Score: 266.82 E-value: 1.78e-89
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Blast search parameters | ||||
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