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Conserved domains on  [gi|359718955|ref|NP_001240784|]
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sperm-associated antigen 6 isoform 4 [Homo sapiens]

Protein Classification

armadillo/beta-catenin-like repeat-containing protein( domain architecture ID 1000979)

armadillo/beta-catenin-like repeat-containing protein similar to Saccharomyces cerevisiae vacuolar protein 8 that functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuole

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SRP1 super family cl34886
Karyopherin (importin) alpha [Intracellular trafficking and secretion];
90-401 1.15e-19

Karyopherin (importin) alpha [Intracellular trafficking and secretion];


The actual alignment was detected with superfamily member COG5064:

Pssm-ID: 227396 [Multi-domain]  Cd Length: 526  Bit Score: 91.88  E-value: 1.15e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359718955  90 KHSPQLaQAIVDCGALDTLVICLEDFDPGVKE-AAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPEIALKRIAASA 168
Cdd:COG5064  102 ETSPPI-QPVIDAGVVPRFVEFMDEIQRDMLQfEAAWALTNIASGTTQQTKVVVDAGAVPLFIQLLSSTEDDVREQAVWA 180

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359718955 169 LSDIAKHSPELAQTVVDAGAVAHLAQMILN--PDAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLKDKDEYVK 246
Cdd:COG5064  181 LGNIAGDSEGCRDYVLQCGALEPLLGLLLSsaIHISMLRNATWTLSNLCRGKNPPPDWSNISQALPILAKLIYSRDPEVL 260

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359718955 247 KNASTLIREIAKHTPELSQLVVNAGGVAAVIDCIGSCKGNTRLPGIMMLGYVAAHSEnLAMAVIISKGVPQLSVCLSEEP 326
Cdd:COG5064  261 VDACWAISYLSDGPNEKIQAVLDVGIPGRLVELLSHESAKIQTPALRSVGNIVTGSD-DQTQVIINCGALKAFRSLLSSP 339

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 359718955 327 EDHIKAAAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYmsteSSEDLQVKSKK--AIKNILQKCTYLPALEPFLYD 401
Cdd:COG5064  340 KENIRKEACWTISNITAGNTEQIQAVIDANLIPPLIHLL----SSAEYKIKKEAcwAISNATSGGLNRPDIIRYLVS 412
 
Name Accession Description Interval E-value
SRP1 COG5064
Karyopherin (importin) alpha [Intracellular trafficking and secretion];
90-401 1.15e-19

Karyopherin (importin) alpha [Intracellular trafficking and secretion];


Pssm-ID: 227396 [Multi-domain]  Cd Length: 526  Bit Score: 91.88  E-value: 1.15e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359718955  90 KHSPQLaQAIVDCGALDTLVICLEDFDPGVKE-AAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPEIALKRIAASA 168
Cdd:COG5064  102 ETSPPI-QPVIDAGVVPRFVEFMDEIQRDMLQfEAAWALTNIASGTTQQTKVVVDAGAVPLFIQLLSSTEDDVREQAVWA 180

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359718955 169 LSDIAKHSPELAQTVVDAGAVAHLAQMILN--PDAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLKDKDEYVK 246
Cdd:COG5064  181 LGNIAGDSEGCRDYVLQCGALEPLLGLLLSsaIHISMLRNATWTLSNLCRGKNPPPDWSNISQALPILAKLIYSRDPEVL 260

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359718955 247 KNASTLIREIAKHTPELSQLVVNAGGVAAVIDCIGSCKGNTRLPGIMMLGYVAAHSEnLAMAVIISKGVPQLSVCLSEEP 326
Cdd:COG5064  261 VDACWAISYLSDGPNEKIQAVLDVGIPGRLVELLSHESAKIQTPALRSVGNIVTGSD-DQTQVIINCGALKAFRSLLSSP 339

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 359718955 327 EDHIKAAAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYmsteSSEDLQVKSKK--AIKNILQKCTYLPALEPFLYD 401
Cdd:COG5064  340 KENIRKEACWTISNITAGNTEQIQAVIDANLIPPLIHLL----SSAEYKIKKEAcwAISNATSGGLNRPDIIRYLVS 412
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 92-132 2.74e-07

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 46.68  E-value: 2.74e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 359718955   92 SPQLAQAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIAR 132
Cdd:pfam00514   1 SPENKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLAA 41
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 92-132 9.72e-06

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 42.42  E-value: 9.72e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 359718955    92 SPQLAQAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIAR 132
Cdd:smart00185   1 DDENKQAVVDAGGLPALVELLKSEDEEVVKEAAWALSNLSS 41
PLN03200 PLN03200
cellulose synthase-interactive protein; Provisional
 99-201 3.35e-03

cellulose synthase-interactive protein; Provisional


Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 40.09  E-value: 3.35e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359718955   99 IVDCGALDTLVICL-EDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVL--------CIQ-EPEIALKRIAASA 168
Cdd:PLN03200  227 VLDAGAVKQLLKLLgQGNEVSVRAEAAGALEALSSQSKEAKQAIADAGGIPALINatvapskeFMQgEFAQALQENAMGA 306

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 359718955  169 LSDI-------------AKHSPELAQTVVDA-GAVAHlAQMILNPDA 201
Cdd:PLN03200  307 LANIcggmsalilylgeLSESPRSPAPIADTlGALAY-ALMVFDSSA 352
 
Name Accession Description Interval E-value
SRP1 COG5064
Karyopherin (importin) alpha [Intracellular trafficking and secretion];
90-401 1.15e-19

Karyopherin (importin) alpha [Intracellular trafficking and secretion];


Pssm-ID: 227396 [Multi-domain]  Cd Length: 526  Bit Score: 91.88  E-value: 1.15e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359718955  90 KHSPQLaQAIVDCGALDTLVICLEDFDPGVKE-AAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPEIALKRIAASA 168
Cdd:COG5064  102 ETSPPI-QPVIDAGVVPRFVEFMDEIQRDMLQfEAAWALTNIASGTTQQTKVVVDAGAVPLFIQLLSSTEDDVREQAVWA 180

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359718955 169 LSDIAKHSPELAQTVVDAGAVAHLAQMILN--PDAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLKDKDEYVK 246
Cdd:COG5064  181 LGNIAGDSEGCRDYVLQCGALEPLLGLLLSsaIHISMLRNATWTLSNLCRGKNPPPDWSNISQALPILAKLIYSRDPEVL 260

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359718955 247 KNASTLIREIAKHTPELSQLVVNAGGVAAVIDCIGSCKGNTRLPGIMMLGYVAAHSEnLAMAVIISKGVPQLSVCLSEEP 326
Cdd:COG5064  261 VDACWAISYLSDGPNEKIQAVLDVGIPGRLVELLSHESAKIQTPALRSVGNIVTGSD-DQTQVIINCGALKAFRSLLSSP 339

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 359718955 327 EDHIKAAAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYmsteSSEDLQVKSKK--AIKNILQKCTYLPALEPFLYD 401
Cdd:COG5064  340 KENIRKEACWTISNITAGNTEQIQAVIDANLIPPLIHLL----SSAEYKIKKEAcwAISNATSGGLNRPDIIRYLVS 412
SRP1 COG5064
Karyopherin (importin) alpha [Intracellular trafficking and secretion];
7-288 3.44e-13

Karyopherin (importin) alpha [Intracellular trafficking and secretion];


Pssm-ID: 227396 [Multi-domain]  Cd Length: 526  Bit Score: 71.46  E-value: 3.44e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359718955   7 TRPQnIETLQNAGVMSLLRTLLLDVVPTIQQ-TAALALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVL 85
Cdd:COG5064  103 TSPP-IQPVIDAGVVPRFVEFMDEIQRDMLQfEAAWALTNIASGTTQQTKVVVDAGAVPLFIQLLSSTEDDVREQAVWAL 181

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359718955  86 RAVGKHSPQLAQAIVDCGALDTLVICLEDFDPGVK--EAAAWALRYIAR-HNAELSQAVVDAgAVPLL--VLCIQEPEIA 160
Cdd:COG5064  182 GNIAGDSEGCRDYVLQCGALEPLLGLLLSSAIHISmlRNATWTLSNLCRgKNPPPDWSNISQ-ALPILakLIYSRDPEVL 260

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359718955 161 LKriAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLKD 240
Cdd:COG5064  261 VD--ACWAISYLSDGPNEKIQAVLDVGIPGRLVELLSHESAKIQTPALRSVGNIVTGSDDQTQVIINCGALKAFRSLLSS 338

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 359718955 241 KDEYVKKNASTLIREIAKHTPELSQLVVNAGGVAAVIDCIGSCKGNTR 288
Cdd:COG5064  339 PKENIRKEACWTISNITAGNTEQIQAVIDANLIPPLIHLLSSAEYKIK 386
SRP1 COG5064
Karyopherin (importin) alpha [Intracellular trafficking and secretion];
17-278 3.86e-13

Karyopherin (importin) alpha [Intracellular trafficking and secretion];


Pssm-ID: 227396 [Multi-domain]  Cd Length: 526  Bit Score: 71.46  E-value: 3.86e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359718955  17 NAGVMSLLRTLLLDVVPTIQQTAALALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYK--KAAAFVLRAV--GKHS 92
Cdd:COG5064  155 DAGAVPLFIQLLSSTEDDVREQAVWALGNIAGDSEGCRDYVLQCGALEPLLGLLLSSAIHISmlRNATWTLSNLcrGKNP 234

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359718955  93 PQLAQAIVDcgALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPEIALKRIAASALSDI 172
Cdd:COG5064  235 PPDWSNISQ--ALPILAKLIYSRDPEVLVDACWAISYLSDGPNEKIQAVLDVGIPGRLVELLSHESAKIQTPALRSVGNI 312

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359718955 173 AKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTL 252
Cdd:COG5064  313 VTGSDDQTQVIINCGALKAFRSLLSSPKENIRKEACWTISNITAGNTEQIQAVIDANLIPPLIHLLSSAEYKIKKEACWA 392

                        250       260
                 ....*....|....*....|....*....
gi 359718955 253 IREIAKH---TPELSQLVVNAGGVAAVID 278
Cdd:COG5064  393 ISNATSGglnRPDIIRYLVSQGFIKPLCD 421
SRP1 COG5064
Karyopherin (importin) alpha [Intracellular trafficking and secretion];
55-338 7.61e-13

Karyopherin (importin) alpha [Intracellular trafficking and secretion];


Pssm-ID: 227396 [Multi-domain]  Cd Length: 526  Bit Score: 70.69  E-value: 7.61e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359718955  55 EAVVKCDILPQLVYSLAE-QNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIARH 133
Cdd:COG5064  108 QPVIDAGVVPRFVEFMDEiQRDMLQFEAAWALTNIASGTTQQTKVVVDAGAVPLFIQLLSSTEDDVREQAVWALGNIAGD 187

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359718955 134 NAELSQAVVDAGAV-PLL-VLCIQEPEIALKRIAASALSDI--AKHSPELAQTVvdAGAVAHLAQMILNPDAKLKHQILS 209
Cdd:COG5064  188 SEGCRDYVLQCGALePLLgLLLSSAIHISMLRNATWTLSNLcrGKNPPPDWSNI--SQALPILAKLIYSRDPEVLVDACW 265

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359718955 210 ALSQVSKHSVDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKHTPELSQLVVNAGGVAAVIDCIGSCKGNTRL 289
Cdd:COG5064  266 AISYLSDGPNEKIQAVLDVGIPGRLVELLSHESAKIQTPALRSVGNIVTGSDDQTQVIINCGALKAFRSLLSSPKENIRK 345

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 359718955 290 PGIMMLGYVAAHSENLAMAVIISKGVPQLsVCLSEEPEDHIKAAAAWAL 338
Cdd:COG5064  346 EACWTISNITAGNTEQIQAVIDANLIPPL-IHLLSSAEYKIKKEACWAI 393
HEAT COG1413
HEAT repeat [General function prediction only];
15-173 1.24e-07

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 50.78  E-value: 1.24e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359718955  15 LQNAGVMSLLRTLLLDVVPTIQQTAALALGRLANynddlAEAVvkcdilPQLVYSLAEQNRFYKKAAAFVLRAVGkhspq 94
Cdd:COG1413   12 LGDPAAVPALIAALADEDPDVRAAAARALGRLGD-----PRAV------PALLEALKDPDPEVRAAAAEALGRIG----- 75

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 359718955  95 laqaivDCGALDTLVICLEDFDPGVKEAAAWALRYIArhnaelsqavvDAGAVPLLVLCIQEPEIALKRIAASALSDIA 173
Cdd:COG1413   76 ------DPEAVPALIAALKDEDPEVRRAAAEALGRLG-----------DPAAVPALLEALKDPDWEVRRAAARALGRLG 137
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 92-132 2.74e-07

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 46.68  E-value: 2.74e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 359718955   92 SPQLAQAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIAR 132
Cdd:pfam00514   1 SPENKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLAA 41
HEAT COG1413
HEAT repeat [General function prediction only];
35-213 1.15e-06

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 47.70  E-value: 1.15e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359718955  35 IQQTAALALGRLANynddlAEAVvkcdilPQLVYSLAEQNRFYKKAAAFVLRAVGkhspqlaqaivDCGALDTLVICLED 114
Cdd:COG1413    1 VRRAAARALGRLGD-----PAAV------PALIAALADEDPDVRAAAARALGRLG-----------DPRAVPALLEALKD 58

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359718955 115 FDPGVKEAAAWALRYIArhnaelsqavvDAGAVPLLVLCIQEPEIALKRIAASALSDIAkhspelaqtvvDAGAVAHLAQ 194
Cdd:COG1413   59 PDPEVRAAAAEALGRIG-----------DPEAVPALIAALKDEDPEVRRAAAEALGRLG-----------DPAAVPALLE 116

                        170
                 ....*....|....*....
gi 359718955 195 MILNPDAKLKHQILSALSQ 213
Cdd:COG1413  117 ALKDPDWEVRRAAARALGR 135
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 92-132 9.72e-06

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 42.42  E-value: 9.72e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 359718955    92 SPQLAQAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIAR 132
Cdd:smart00185   1 DDENKQAVVDAGGLPALVELLKSEDEEVVKEAAWALSNLSS 41
SRP1 COG5064
Karyopherin (importin) alpha [Intracellular trafficking and secretion];
12-216 2.27e-05

Karyopherin (importin) alpha [Intracellular trafficking and secretion];


Pssm-ID: 227396 [Multi-domain]  Cd Length: 526  Bit Score: 46.81  E-value: 2.27e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359718955  12 IETLQNAGVMSLLRTLLLDVVPTIQQTAALALGRLANYNDDLAEavvkcdilpqlvyslaeqnrfykkaaafvlravgkh 91
Cdd:COG5064  278 IQAVLDVGIPGRLVELLSHESAKIQTPALRSVGNIVTGSDDQTQ------------------------------------ 321

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359718955  92 spqlaqAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPEIALKRIAASALSD 171
Cdd:COG5064  322 ------VIINCGALKAFRSLLSSPKENIRKEACWTISNITAGNTEQIQAVIDANLIPPLIHLLSSAEYKIKKEACWAISN 395

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 359718955 172 IAKHS---PELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSK 216
Cdd:COG5064  396 ATSGGlnrPDIIRYLVSQGFIKPLCDLLDVVDNKIIEVALDAIENILK 443
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 134-173 4.96e-04

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 37.43  E-value: 4.96e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 359718955  134 NAELSQAVVDAGAVPLLVLCIQEPEIALKRIAASALSDIA 173
Cdd:pfam00514   1 SPENKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLA 40
HEAT COG1413
HEAT repeat [General function prediction only];
119-256 8.23e-04

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 39.61  E-value: 8.23e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359718955 119 VKEAAAWALRYIArhnaelsqavvDAGAVPLLVLCIQEPEIALKRIAASALSDIAkhspelaqtvvDAGAVAHLAQMILN 198
Cdd:COG1413    1 VRRAAARALGRLG-----------DPAAVPALIAALADEDPDVRAAAARALGRLG-----------DPRAVPALLEALKD 58

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 359718955 199 PDAKLKHQILSALSQVSkhsvdlaemvvEAEIFPVVLTCLKDKDEYVKKNASTLIREI 256
Cdd:COG1413   59 PDPEVRAAAAEALGRIG-----------DPEAVPALIAALKDEDPEVRRAAAEALGRL 105
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 176-212 2.07e-03

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 35.89  E-value: 2.07e-03
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 359718955  176 SPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALS 212
Cdd:pfam00514   1 SPENKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALS 37
PLN03200 PLN03200
cellulose synthase-interactive protein; Provisional
 99-201 3.35e-03

cellulose synthase-interactive protein; Provisional


Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 40.09  E-value: 3.35e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359718955   99 IVDCGALDTLVICL-EDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVL--------CIQ-EPEIALKRIAASA 168
Cdd:PLN03200  227 VLDAGAVKQLLKLLgQGNEVSVRAEAAGALEALSSQSKEAKQAIADAGGIPALINatvapskeFMQgEFAQALQENAMGA 306

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 359718955  169 LSDI-------------AKHSPELAQTVVDA-GAVAHlAQMILNPDA 201
Cdd:PLN03200  307 LANIcggmsalilylgeLSESPRSPAPIADTlGALAY-ALMVFDSSA 352
HEAT_EZ pfam13513
HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats ...
 117-172 3.83e-03

HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats (see pfam00514). These EZ repeats are found in subunits of cyanobacterial phycocyanin lyase and other proteins and probably carry out a scaffolding role.


Pssm-ID: 463906 [Multi-domain]  Cd Length: 55  Bit Score: 35.42  E-value: 3.83e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 359718955  117 PGVKEAAAWALRYIARHNAELSQAVVDAgAVPLLVLCIQEPEIALKRIAASALSDI 172
Cdd:pfam13513   1 WRVREAAALALGSLAEGGPDLLAPAVPE-LLPALLPLLNDDSDLVREAAAWALGRL 55
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 176-216 5.37e-03

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 34.71  E-value: 5.37e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 359718955   176 SPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSK 216
Cdd:smart00185   1 DDENKQAVVDAGGLPALVELLKSEDEEVVKEAAWALSNLSS 41
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 134-174 7.15e-03

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 34.33  E-value: 7.15e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 359718955   134 NAELSQAVVDAGAVPLLVLCIQEPEIALKRIAASALSDIAK 174
Cdd:smart00185   1 DDENKQAVVDAGGLPALVELLKSEDEEVVKEAAWALSNLSS 41
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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