NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|472235298|ref|NP_001264235|]
View 

MAU2 chromatid cohesion factor homolog isoform 2 [Rattus norvegicus]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Cohesin_load super family cl20398
Cohesin loading factor; Cohesin_load is a common cohesin loading factor protein that is ...
 31-101 4.18e-17

Cohesin loading factor; Cohesin_load is a common cohesin loading factor protein that is conserved in fungi. It is associated with the cohesin complex and is required in G1 for cohesin binding to chromosomes but dispensable in G2 when cohesion has been established. It is referred to as both Ssl3, in pombe, and Scc4, in S.cerevisiae. It complexes with Mis4.


The actual alignment was detected with superfamily member pfam10345:

Pssm-ID: 463053 [Multi-domain]  Cd Length: 585  Bit Score: 74.66  E-value: 4.18e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472235298   31 WYLALLGFAEHFRTSSPP----------------KIRLCVHCLQAVF-PFKPPQRIEARTHLQLGSVLYHHTKNSEQARS 93
Cdd:pfam10345   1 YVALLLSLAEEYLTAAHKmvalvrseedleqyykLIATGLGCLEAVLkNFSLPPRQEARIRLRLASLLLEETENLDEAEE 80


                  ....*...
gi 472235298   94 HLEKAVPL 101
Cdd:pfam10345  81 YLSKAITL 88
 
Name Accession Description Interval E-value
Cohesin_load pfam10345
Cohesin loading factor; Cohesin_load is a common cohesin loading factor protein that is ...
 31-101 4.18e-17

Cohesin loading factor; Cohesin_load is a common cohesin loading factor protein that is conserved in fungi. It is associated with the cohesin complex and is required in G1 for cohesin binding to chromosomes but dispensable in G2 when cohesion has been established. It is referred to as both Ssl3, in pombe, and Scc4, in S.cerevisiae. It complexes with Mis4.


Pssm-ID: 463053 [Multi-domain]  Cd Length: 585  Bit Score: 74.66  E-value: 4.18e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472235298   31 WYLALLGFAEHFRTSSPP----------------KIRLCVHCLQAVF-PFKPPQRIEARTHLQLGSVLYHHTKNSEQARS 93
Cdd:pfam10345   1 YVALLLSLAEEYLTAAHKmvalvrseedleqyykLIATGLGCLEAVLkNFSLPPRQEARIRLRLASLLLEETENLDEAEE 80


                  ....*...
gi 472235298   94 HLEKAVPL 101
Cdd:pfam10345  81 YLSKAITL 88
 
Name Accession Description Interval E-value
Cohesin_load pfam10345
Cohesin loading factor; Cohesin_load is a common cohesin loading factor protein that is ...
 31-101 4.18e-17

Cohesin loading factor; Cohesin_load is a common cohesin loading factor protein that is conserved in fungi. It is associated with the cohesin complex and is required in G1 for cohesin binding to chromosomes but dispensable in G2 when cohesion has been established. It is referred to as both Ssl3, in pombe, and Scc4, in S.cerevisiae. It complexes with Mis4.


Pssm-ID: 463053 [Multi-domain]  Cd Length: 585  Bit Score: 74.66  E-value: 4.18e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472235298   31 WYLALLGFAEHFRTSSPP----------------KIRLCVHCLQAVF-PFKPPQRIEARTHLQLGSVLYHHTKNSEQARS 93
Cdd:pfam10345   1 YVALLLSLAEEYLTAAHKmvalvrseedleqyykLIATGLGCLEAVLkNFSLPPRQEARIRLRLASLLLEETENLDEAEE 80


                  ....*...
gi 472235298   94 HLEKAVPL 101
Cdd:pfam10345  81 YLSKAITL 88
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH