NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|600971694|ref|NP_001278112|]
View 

matrix extracellular phosphoglycoprotein isoform c precursor [Homo sapiens]

Protein Classification

Osteoregulin domain-containing protein( domain architecture ID 10537541)

Osteoregulin domain-containing protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Osteoregulin pfam07175
Osteoregulin; This family represents a conserved region approximately 180 residues long within ...
 128-287 1.11e-100

Osteoregulin; This family represents a conserved region approximately 180 residues long within osteoregulin, a bone-remodelling protein expressed highly in osteocytes within trabecular and cortical bone. A conserved RGD motif is found towards the C-terminal end of this region, and this is potentially involved in integrin recognition.


:

Pssm-ID: 399867  Cd Length: 160  Bit Score: 301.00  E-value: 1.11e-100
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 600971694  128 NKEYSISNKENTHNGLRMSIYPKSTGNKGFEDGDDAISKLHDQEEYGAALIRNNMQHIMGPVTAIKLLGEENKENTPRNV 207
Cdd:pfam07175   1 NEDYSISNKENAHNDLKMSIYPESTGNNGAEDGDDAISKLHDQEEYGAALIRNNMQHIMEPVTVTELLGEENKENKPRNV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 600971694  208 LNIIPASMNYAKAHSKDKKKPQRDSQAQKSPVKSKSTHRIQHNIDYLKHLSKVKKIPSDFEGSGYTDLQERGDNDISPFS 287
Cdd:pfam07175  81 LSKIPADVNYAKAHSKDKKNHQRDLQAQNSPVKSKSTHHIQHNTDYLKQLPKVKKIPSDFEGSGYPDLQERGDNDISPFS 160
 
Name Accession Description Interval E-value
Osteoregulin pfam07175
Osteoregulin; This family represents a conserved region approximately 180 residues long within ...
 128-287 1.11e-100

Osteoregulin; This family represents a conserved region approximately 180 residues long within osteoregulin, a bone-remodelling protein expressed highly in osteocytes within trabecular and cortical bone. A conserved RGD motif is found towards the C-terminal end of this region, and this is potentially involved in integrin recognition.


Pssm-ID: 399867  Cd Length: 160  Bit Score: 301.00  E-value: 1.11e-100
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 600971694  128 NKEYSISNKENTHNGLRMSIYPKSTGNKGFEDGDDAISKLHDQEEYGAALIRNNMQHIMGPVTAIKLLGEENKENTPRNV 207
Cdd:pfam07175   1 NEDYSISNKENAHNDLKMSIYPESTGNNGAEDGDDAISKLHDQEEYGAALIRNNMQHIMEPVTVTELLGEENKENKPRNV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 600971694  208 LNIIPASMNYAKAHSKDKKKPQRDSQAQKSPVKSKSTHRIQHNIDYLKHLSKVKKIPSDFEGSGYTDLQERGDNDISPFS 287
Cdd:pfam07175  81 LSKIPADVNYAKAHSKDKKNHQRDLQAQNSPVKSKSTHHIQHNTDYLKQLPKVKKIPSDFEGSGYPDLQERGDNDISPFS 160
 
Name Accession Description Interval E-value
Osteoregulin pfam07175
Osteoregulin; This family represents a conserved region approximately 180 residues long within ...
 128-287 1.11e-100

Osteoregulin; This family represents a conserved region approximately 180 residues long within osteoregulin, a bone-remodelling protein expressed highly in osteocytes within trabecular and cortical bone. A conserved RGD motif is found towards the C-terminal end of this region, and this is potentially involved in integrin recognition.


Pssm-ID: 399867  Cd Length: 160  Bit Score: 301.00  E-value: 1.11e-100
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 600971694  128 NKEYSISNKENTHNGLRMSIYPKSTGNKGFEDGDDAISKLHDQEEYGAALIRNNMQHIMGPVTAIKLLGEENKENTPRNV 207
Cdd:pfam07175   1 NEDYSISNKENAHNDLKMSIYPESTGNNGAEDGDDAISKLHDQEEYGAALIRNNMQHIMEPVTVTELLGEENKENKPRNV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 600971694  208 LNIIPASMNYAKAHSKDKKKPQRDSQAQKSPVKSKSTHRIQHNIDYLKHLSKVKKIPSDFEGSGYTDLQERGDNDISPFS 287
Cdd:pfam07175  81 LSKIPADVNYAKAHSKDKKNHQRDLQAQNSPVKSKSTHHIQHNTDYLKQLPKVKKIPSDFEGSGYPDLQERGDNDISPFS 160
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH