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Conserved domains on  [gi|918410291|ref|NP_001299618|]
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outer dynein arm-docking complex subunit 2 isoform 3 [Homo sapiens]

Protein Classification

Arm and SRP1 domain-containing protein( domain architecture ID 13633099)

Arm and SRP1 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HEAT COG1413
HEAT repeat [General function prediction only];
575-724 3.04e-08

HEAT repeat [General function prediction only];


:

Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 53.09  E-value: 3.04e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918410291 575 LELIVNLLKSDNKEVLASVCAAitniakdqenLAVITDHGVVPLLSKLANTNNNKLRHHLAEAISRccmwgrnrvaFGEH 654
Cdd:COG1413   18 VPALIAALADEDPDVRAAAARA----------LGRLGDPRAVPALLEALKDPDPEVRAAAAEALGR----------IGDP 77

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918410291 655 KAVAPLVRYLKSNDTNVHRATAQALYQLSEDAdncitmhengAVKLLLDMVGSPDQDLQEAAAGCISNIR 724
Cdd:COG1413   78 EAVPALIAALKDEDPEVRRAAAEALGRLGDPA----------AVPALLEALKDPDWEVRRAAARALGRLG 137
SRP1 super family cl34886
Karyopherin (importin) alpha [Intracellular trafficking and secretion];
349-734 1.77e-07

Karyopherin (importin) alpha [Intracellular trafficking and secretion];


The actual alignment was detected with superfamily member COG5064:

Pssm-ID: 227396 [Multi-domain]  Cd Length: 526  Bit Score: 54.51  E-value: 1.77e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918410291 349 QECASEENYRAAIKAERIIENLVKNLNSENEQLQeHCAMAIYQCAEDKETR---DLVRLHGGLKPLASLLNNTDNKERLA 425
Cdd:COG5064   55 SEEAESSFIPMEQQFYSELPQLTQQLFSDDIEQQ-LQAVYKFRKLLSKETSppiQPVIDAGVVPRFVEFMDEIQRDMLQF 133

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918410291 426 AVTGAIWKCSISKENVTKFR-EYKAIETLVGLLTDQPEEVLVNVVGALGECCQEREN-RVIVRKCGGIQPLVNLLV--GI 501
Cdd:COG5064  134 EAAWALTNIASGTTQQTKVVvDAGAVPLFIQLLSSTEDDVREQAVWALGNIAGDSEGcRDYVLQCGALEPLLGLLLssAI 213

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918410291 502 NQALLVNVTKAVG-ACAVE--PESMMIIDRldGVRLLWSLLKNPHPDVKASAAWALC-------PCIKNAKDAGEMVRsf 571
Cdd:COG5064  214 HISMLRNATWTLSnLCRGKnpPPDWSNISQ--ALPILAKLIYSRDPEVLVDACWAISylsdgpnEKIQAVLDVGIPGR-- 289

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918410291 572 vgglelIVNLLKSDNKEVLASVCAAITNIAK-DQENLAVITDHGVVPLLSKLANTNNNKLRHHLAEAISRCCMWGRNRV- 649
Cdd:COG5064  290 ------LVELLSHESAKIQTPALRSVGNIVTgSDDQTQVIINCGALKAFRSLLSSPKENIRKEACWTISNITAGNTEQIq 363

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918410291 650 AFGEHKAVAPLVRYLKSNDTNVHR----ATAQALYQLSEDADNCITMHENGAVKLLLDMVGSPDQDLQEAAAGCISNIRR 725
Cdd:COG5064  364 AVIDANLIPPLIHLLSSAEYKIKKeacwAISNATSGGLNRPDIIRYLVSQGFIKPLCDLLDVVDNKIIEVALDAIENILK 443


                 ....*....
gi 918410291 726 LALATEKAR 734
Cdd:COG5064  444 VGEQDRLRY 452
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 316-353 1.04e-03

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


:

Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 37.05  E-value: 1.04e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 918410291  316 NKEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQECAS 353
Cdd:pfam00514   4 NKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLAA 41
PLN03200 super family cl33659
cellulose synthase-interactive protein; Provisional
 141-376 2.06e-03

cellulose synthase-interactive protein; Provisional


The actual alignment was detected with superfamily member PLN03200:

Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 41.63  E-value: 2.06e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918410291  141 SEYWQ---IQKLVKYLKGGNQTATVIALCSMRDFSLAQETCQLAIRDVGGLEVLINLLETDEvkCKIGSLKILKEISHNP 217
Cdd:PLN03200 1644 SEYYFevpVAVLVKLLRSTSESTVVVALNALLVLERDDSSSAEQMAESGAIEALLELLRSHQ--CEEAAARLLEALFNNV 1721

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918410291  218 QIRQ-NIVDLGGLPIMVNILDsPH---KSLKCLAAETIANVAkfkrarrvvrQHGGITKlvalldcAHDSTKP--AQSSL 291
Cdd:PLN03200 1722 KVREmKATKYAIAPLSQYLLD-PQtrsQQARLLAALALGDLF----------QHEGLAR-------STDAVSAcrALVSL 1783

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918410291  292 YEARDVE----VARCGALALWSCSKshTNKEAIRKAGGIPLLARLLKTSHEN------MLIPVV---GTLQECASEENYR 358
Cdd:PLN03200 1784 LEDQPTEemkmVAICALQNLVMHSR--TNKRAVAEAGGVQVVQELLLSSNPDtsgqaaLLIKLLfsnHTIQEYASSELIR 1861

                         250       260
                  ....*....|....*....|....*.
gi 918410291  359 ---AAIKAE-----RIIENLVKNLNS 376
Cdd:PLN03200 1862 altAALEKDlwstaTVNEEVLRALNV 1887
 
Name Accession Description Interval E-value
HEAT COG1413
HEAT repeat [General function prediction only];
575-724 3.04e-08

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 53.09  E-value: 3.04e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918410291 575 LELIVNLLKSDNKEVLASVCAAitniakdqenLAVITDHGVVPLLSKLANTNNNKLRHHLAEAISRccmwgrnrvaFGEH 654
Cdd:COG1413   18 VPALIAALADEDPDVRAAAARA----------LGRLGDPRAVPALLEALKDPDPEVRAAAAEALGR----------IGDP 77

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918410291 655 KAVAPLVRYLKSNDTNVHRATAQALYQLSEDAdncitmhengAVKLLLDMVGSPDQDLQEAAAGCISNIR 724
Cdd:COG1413   78 EAVPALIAALKDEDPEVRRAAAEALGRLGDPA----------AVPALLEALKDPDWEVRRAAARALGRLG 137
SRP1 COG5064
Karyopherin (importin) alpha [Intracellular trafficking and secretion];
349-734 1.77e-07

Karyopherin (importin) alpha [Intracellular trafficking and secretion];


Pssm-ID: 227396 [Multi-domain]  Cd Length: 526  Bit Score: 54.51  E-value: 1.77e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918410291 349 QECASEENYRAAIKAERIIENLVKNLNSENEQLQeHCAMAIYQCAEDKETR---DLVRLHGGLKPLASLLNNTDNKERLA 425
Cdd:COG5064   55 SEEAESSFIPMEQQFYSELPQLTQQLFSDDIEQQ-LQAVYKFRKLLSKETSppiQPVIDAGVVPRFVEFMDEIQRDMLQF 133

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918410291 426 AVTGAIWKCSISKENVTKFR-EYKAIETLVGLLTDQPEEVLVNVVGALGECCQEREN-RVIVRKCGGIQPLVNLLV--GI 501
Cdd:COG5064  134 EAAWALTNIASGTTQQTKVVvDAGAVPLFIQLLSSTEDDVREQAVWALGNIAGDSEGcRDYVLQCGALEPLLGLLLssAI 213

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918410291 502 NQALLVNVTKAVG-ACAVE--PESMMIIDRldGVRLLWSLLKNPHPDVKASAAWALC-------PCIKNAKDAGEMVRsf 571
Cdd:COG5064  214 HISMLRNATWTLSnLCRGKnpPPDWSNISQ--ALPILAKLIYSRDPEVLVDACWAISylsdgpnEKIQAVLDVGIPGR-- 289

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918410291 572 vgglelIVNLLKSDNKEVLASVCAAITNIAK-DQENLAVITDHGVVPLLSKLANTNNNKLRHHLAEAISRCCMWGRNRV- 649
Cdd:COG5064  290 ------LVELLSHESAKIQTPALRSVGNIVTgSDDQTQVIINCGALKAFRSLLSSPKENIRKEACWTISNITAGNTEQIq 363

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918410291 650 AFGEHKAVAPLVRYLKSNDTNVHR----ATAQALYQLSEDADNCITMHENGAVKLLLDMVGSPDQDLQEAAAGCISNIRR 725
Cdd:COG5064  364 AVIDANLIPPLIHLLSSAEYKIKKeacwAISNATSGGLNRPDIIRYLVSQGFIKPLCDLLDVVDNKIIEVALDAIENILK 443


                 ....*....
gi 918410291 726 LALATEKAR 734
Cdd:COG5064  444 VGEQDRLRY 452
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 316-353 1.04e-03

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 37.05  E-value: 1.04e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 918410291  316 NKEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQECAS 353
Cdd:pfam00514   4 NKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLAA 41
PLN03200 PLN03200
cellulose synthase-interactive protein; Provisional
 317-554 1.29e-03

cellulose synthase-interactive protein; Provisional


Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 42.40  E-value: 1.29e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918410291  317 KEAIRKAGGIPLLARLLKT----SHENMLIpVVGTLqeCASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQC 392
Cdd:PLN03200  481 KWAITAAGGIPPLVQLLETgsqkAKEDSAT-VLWNL--CCHSEDIRACVESAGAVPALLWLLKNGGPKGQEIAAKTLTKL 557

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918410291  393 AEDKETRDLVRLhgglkpLASLLNNT-DNKERLAAVTGAIWkCSISKENVtkFRE----YKAIETLVGLLTDQPEEVLVN 467
Cdd:PLN03200  558 VRTADAATISQL------TALLLGDLpESKVHVLDVLGHVL-SVASLEDL--VREgsaaNDALRTLIQLLSSSKEETQEK 628

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918410291  468 VVGALGECCQERENRvivrkCGG------IQPLVNLLVGINQALLVNVTKAVGA---CAVEPESMMIIDRlDGVRLLWSL 538
Cdd:PLN03200  629 AASVLADIFSSRQDL-----CESlatdeiINPCIKLLTNNTEAVATQSARALAAlsrSIKENRKVSYAAE-DAIKPLIKL 702

                         250
                  ....*....|....*.
gi 918410291  539 LKNPHPDVKASAAWAL 554
Cdd:PLN03200  703 AKSSSIEVAEQAVCAL 718
HEAT_2 pfam13646
HEAT repeats; This family includes multiple HEAT repeats.
 534-639 1.36e-03

HEAT repeats; This family includes multiple HEAT repeats.


Pssm-ID: 433376 [Multi-domain]  Cd Length: 88  Bit Score: 38.47  E-value: 1.36e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918410291  534 LLWSLLKNPHPDVKASAAWALCPCikNAKDAgemvrsfvggLELIVNLLKSDNKEVLASVCAAitniakdqenLAVITDH 613
Cdd:pfam13646   4 LLQALLRDPDPEVRAAAIRALGRI--GDPEA----------VPALLELLKDEDPAVRRAAAEA----------LGKIGDP 61

                          90       100
                  ....*....|....*....|....*..
gi 918410291  614 GVVPLLSKLANTNNNK-LRHHLAEAIS 639
Cdd:pfam13646  62 EALPALLELLRDDDDDvVRAAAAEALA 88
PLN03200 PLN03200
cellulose synthase-interactive protein; Provisional
 141-376 2.06e-03

cellulose synthase-interactive protein; Provisional


Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 41.63  E-value: 2.06e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918410291  141 SEYWQ---IQKLVKYLKGGNQTATVIALCSMRDFSLAQETCQLAIRDVGGLEVLINLLETDEvkCKIGSLKILKEISHNP 217
Cdd:PLN03200 1644 SEYYFevpVAVLVKLLRSTSESTVVVALNALLVLERDDSSSAEQMAESGAIEALLELLRSHQ--CEEAAARLLEALFNNV 1721

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918410291  218 QIRQ-NIVDLGGLPIMVNILDsPH---KSLKCLAAETIANVAkfkrarrvvrQHGGITKlvalldcAHDSTKP--AQSSL 291
Cdd:PLN03200 1722 KVREmKATKYAIAPLSQYLLD-PQtrsQQARLLAALALGDLF----------QHEGLAR-------STDAVSAcrALVSL 1783

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918410291  292 YEARDVE----VARCGALALWSCSKshTNKEAIRKAGGIPLLARLLKTSHEN------MLIPVV---GTLQECASEENYR 358
Cdd:PLN03200 1784 LEDQPTEemkmVAICALQNLVMHSR--TNKRAVAEAGGVQVVQELLLSSNPDtsgqaaLLIKLLfsnHTIQEYASSELIR 1861

                         250       260
                  ....*....|....*....|....*.
gi 918410291  359 ---AAIKAE-----RIIENLVKNLNS 376
Cdd:PLN03200 1862 altAALEKDlwstaTVNEEVLRALNV 1887
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 216-255 3.09e-03

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 35.89  E-value: 3.09e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 918410291  216 NPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAAETIANVA 255
Cdd:pfam00514   1 SPENKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLA 40
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 313-348 3.86e-03

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 35.48  E-value: 3.86e-03
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 918410291   313 SHTNKEAIRKAGGIPLLARLLKTSHENMLIPVVGTL 348
Cdd:smart00185   1 DDENKQAVVDAGGLPALVELLKSEDEEVVKEAAWAL 36
 
Name Accession Description Interval E-value
HEAT COG1413
HEAT repeat [General function prediction only];
575-724 3.04e-08

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 53.09  E-value: 3.04e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918410291 575 LELIVNLLKSDNKEVLASVCAAitniakdqenLAVITDHGVVPLLSKLANTNNNKLRHHLAEAISRccmwgrnrvaFGEH 654
Cdd:COG1413   18 VPALIAALADEDPDVRAAAARA----------LGRLGDPRAVPALLEALKDPDPEVRAAAAEALGR----------IGDP 77

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918410291 655 KAVAPLVRYLKSNDTNVHRATAQALYQLSEDAdncitmhengAVKLLLDMVGSPDQDLQEAAAGCISNIR 724
Cdd:COG1413   78 EAVPALIAALKDEDPEVRRAAAEALGRLGDPA----------AVPALLEALKDPDWEVRRAAARALGRLG 137
SRP1 COG5064
Karyopherin (importin) alpha [Intracellular trafficking and secretion];
349-734 1.77e-07

Karyopherin (importin) alpha [Intracellular trafficking and secretion];


Pssm-ID: 227396 [Multi-domain]  Cd Length: 526  Bit Score: 54.51  E-value: 1.77e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918410291 349 QECASEENYRAAIKAERIIENLVKNLNSENEQLQeHCAMAIYQCAEDKETR---DLVRLHGGLKPLASLLNNTDNKERLA 425
Cdd:COG5064   55 SEEAESSFIPMEQQFYSELPQLTQQLFSDDIEQQ-LQAVYKFRKLLSKETSppiQPVIDAGVVPRFVEFMDEIQRDMLQF 133

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918410291 426 AVTGAIWKCSISKENVTKFR-EYKAIETLVGLLTDQPEEVLVNVVGALGECCQEREN-RVIVRKCGGIQPLVNLLV--GI 501
Cdd:COG5064  134 EAAWALTNIASGTTQQTKVVvDAGAVPLFIQLLSSTEDDVREQAVWALGNIAGDSEGcRDYVLQCGALEPLLGLLLssAI 213

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918410291 502 NQALLVNVTKAVG-ACAVE--PESMMIIDRldGVRLLWSLLKNPHPDVKASAAWALC-------PCIKNAKDAGEMVRsf 571
Cdd:COG5064  214 HISMLRNATWTLSnLCRGKnpPPDWSNISQ--ALPILAKLIYSRDPEVLVDACWAISylsdgpnEKIQAVLDVGIPGR-- 289

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918410291 572 vgglelIVNLLKSDNKEVLASVCAAITNIAK-DQENLAVITDHGVVPLLSKLANTNNNKLRHHLAEAISRCCMWGRNRV- 649
Cdd:COG5064  290 ------LVELLSHESAKIQTPALRSVGNIVTgSDDQTQVIINCGALKAFRSLLSSPKENIRKEACWTISNITAGNTEQIq 363

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918410291 650 AFGEHKAVAPLVRYLKSNDTNVHR----ATAQALYQLSEDADNCITMHENGAVKLLLDMVGSPDQDLQEAAAGCISNIRR 725
Cdd:COG5064  364 AVIDANLIPPLIHLLSSAEYKIKKeacwAISNATSGGLNRPDIIRYLVSQGFIKPLCDLLDVVDNKIIEVALDAIENILK 443


                 ....*....
gi 918410291 726 LALATEKAR 734
Cdd:COG5064  444 VGEQDRLRY 452
HEAT COG1413
HEAT repeat [General function prediction only];
532-682 1.22e-06

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 48.47  E-value: 1.22e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918410291 532 VRLLWSLLKNPHPDVKASAAWALcpciknakdaGEMVRSfvGGLELIVNLLKSDNKEVLASVCAAITNIAKDQenlavit 611
Cdd:COG1413   18 VPALIAALADEDPDVRAAAARAL----------GRLGDP--RAVPALLEALKDPDPEVRAAAAEALGRIGDPE------- 78

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 918410291 612 dhgVVPLLSKLANTNNNKLRHHLAEAISRccmwgrnrvaFGEHKAVAPLVRYLKSNDTNVHRATAQALYQL 682
Cdd:COG1413   79 ---AVPALIAALKDEDPEVRRAAAEALGR----------LGDPAAVPALLEALKDPDWEVRRAAARALGRL 136
HEAT COG1413
HEAT repeat [General function prediction only];
319-474 5.79e-05

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 43.46  E-value: 5.79e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918410291 319 AIRKAGGIPLLARLLKTSHENMLIPVVGTLqecaseenyrAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDKet 398
Cdd:COG1413   11 RLGDPAAVPALIAALADEDPDVRAAAARAL----------GRLGDPRAVPALLEALKDPDPEVRAAAAEALGRIGDPE-- 78

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 918410291 399 rdlvrlhgGLKPLASLLNNTDNKERLAAVTGaiwkcsiskenVTKFREYKAIETLVGLLTDQPEEVLVNVVGALGE 474
Cdd:COG1413   79 --------AVPALIAALKDEDPEVRRAAAEA-----------LGRLGDPAAVPALLEALKDPDWEVRRAAARALGR 135
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 316-353 1.04e-03

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 37.05  E-value: 1.04e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 918410291  316 NKEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQECAS 353
Cdd:pfam00514   4 NKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLAA 41
PLN03200 PLN03200
cellulose synthase-interactive protein; Provisional
 317-554 1.29e-03

cellulose synthase-interactive protein; Provisional


Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 42.40  E-value: 1.29e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918410291  317 KEAIRKAGGIPLLARLLKT----SHENMLIpVVGTLqeCASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQC 392
Cdd:PLN03200  481 KWAITAAGGIPPLVQLLETgsqkAKEDSAT-VLWNL--CCHSEDIRACVESAGAVPALLWLLKNGGPKGQEIAAKTLTKL 557

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918410291  393 AEDKETRDLVRLhgglkpLASLLNNT-DNKERLAAVTGAIWkCSISKENVtkFRE----YKAIETLVGLLTDQPEEVLVN 467
Cdd:PLN03200  558 VRTADAATISQL------TALLLGDLpESKVHVLDVLGHVL-SVASLEDL--VREgsaaNDALRTLIQLLSSSKEETQEK 628

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918410291  468 VVGALGECCQERENRvivrkCGG------IQPLVNLLVGINQALLVNVTKAVGA---CAVEPESMMIIDRlDGVRLLWSL 538
Cdd:PLN03200  629 AASVLADIFSSRQDL-----CESlatdeiINPCIKLLTNNTEAVATQSARALAAlsrSIKENRKVSYAAE-DAIKPLIKL 702

                         250
                  ....*....|....*.
gi 918410291  539 LKNPHPDVKASAAWAL 554
Cdd:PLN03200  703 AKSSSIEVAEQAVCAL 718
HEAT_2 pfam13646
HEAT repeats; This family includes multiple HEAT repeats.
 534-639 1.36e-03

HEAT repeats; This family includes multiple HEAT repeats.


Pssm-ID: 433376 [Multi-domain]  Cd Length: 88  Bit Score: 38.47  E-value: 1.36e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918410291  534 LLWSLLKNPHPDVKASAAWALCPCikNAKDAgemvrsfvggLELIVNLLKSDNKEVLASVCAAitniakdqenLAVITDH 613
Cdd:pfam13646   4 LLQALLRDPDPEVRAAAIRALGRI--GDPEA----------VPALLELLKDEDPAVRRAAAEA----------LGKIGDP 61

                          90       100
                  ....*....|....*....|....*..
gi 918410291  614 GVVPLLSKLANTNNNK-LRHHLAEAIS 639
Cdd:pfam13646  62 EALPALLELLRDDDDDvVRAAAAEALA 88
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 694-723 1.76e-03

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 36.66  E-value: 1.76e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 918410291  694 ENGAVKLLLDMVGSPDQDLQEAAAGCISNI 723
Cdd:pfam00514  10 EAGAVPPLVRLLSSPDEEVQEEAAWALSNL 39
PLN03200 PLN03200
cellulose synthase-interactive protein; Provisional
 141-376 2.06e-03

cellulose synthase-interactive protein; Provisional


Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 41.63  E-value: 2.06e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918410291  141 SEYWQ---IQKLVKYLKGGNQTATVIALCSMRDFSLAQETCQLAIRDVGGLEVLINLLETDEvkCKIGSLKILKEISHNP 217
Cdd:PLN03200 1644 SEYYFevpVAVLVKLLRSTSESTVVVALNALLVLERDDSSSAEQMAESGAIEALLELLRSHQ--CEEAAARLLEALFNNV 1721

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918410291  218 QIRQ-NIVDLGGLPIMVNILDsPH---KSLKCLAAETIANVAkfkrarrvvrQHGGITKlvalldcAHDSTKP--AQSSL 291
Cdd:PLN03200 1722 KVREmKATKYAIAPLSQYLLD-PQtrsQQARLLAALALGDLF----------QHEGLAR-------STDAVSAcrALVSL 1783

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918410291  292 YEARDVE----VARCGALALWSCSKshTNKEAIRKAGGIPLLARLLKTSHEN------MLIPVV---GTLQECASEENYR 358
Cdd:PLN03200 1784 LEDQPTEemkmVAICALQNLVMHSR--TNKRAVAEAGGVQVVQELLLSSNPDtsgqaaLLIKLLfsnHTIQEYASSELIR 1861

                         250       260
                  ....*....|....*....|....*.
gi 918410291  359 ---AAIKAE-----RIIENLVKNLNS 376
Cdd:PLN03200 1862 altAALEKDlwstaTVNEEVLRALNV 1887
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 216-255 3.09e-03

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 35.89  E-value: 3.09e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 918410291  216 NPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAAETIANVA 255
Cdd:pfam00514   1 SPENKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLA 40
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 313-348 3.86e-03

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 35.48  E-value: 3.86e-03
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 918410291   313 SHTNKEAIRKAGGIPLLARLLKTSHENMLIPVVGTL 348
Cdd:smart00185   1 DDENKQAVVDAGGLPALVELLKSEDEEVVKEAAWAL 36
HEAT_2 pfam13646
HEAT repeats; This family includes multiple HEAT repeats.
 615-717 4.95e-03

HEAT repeats; This family includes multiple HEAT repeats.


Pssm-ID: 433376 [Multi-domain]  Cd Length: 88  Bit Score: 36.93  E-value: 4.95e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918410291  615 VVPLLSKLANTNNNKLRHHLAEAISRccmwgrnrvaFGEHKAVAPLVRYLKSNDTNVHRATAQALYQLSEDAdncitmhe 694
Cdd:pfam13646   1 LPALLQALLRDPDPEVRAAAIRALGR----------IGDPEAVPALLELLKDEDPAVRRAAAEALGKIGDPE-------- 62

                          90       100
                  ....*....|....*....|....
gi 918410291  695 ngAVKLLLDMVGS-PDQDLQEAAA 717
Cdd:pfam13646  63 --ALPALLELLRDdDDDVVRAAAA 84
HEAT COG1413
HEAT repeat [General function prediction only];
448-640 7.26e-03

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 37.30  E-value: 7.26e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918410291 448 KAIETLVGLLTDQPEEVLVNVVGALGECCQERenrvivrkcggiqplvnllvginqallvnvtkavgacAVEPesmmiid 527
Cdd:COG1413   16 AAVPALIAALADEDPDVRAAAARALGRLGDPR-------------------------------------AVPA------- 51

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918410291 528 rldgvrlLWSLLKNPHPDVKASAAWALCpCIKNAKdagemvrsfvgGLELIVNLLKSDNKEVLASVCAAitniakdqenL 607
Cdd:COG1413   52 -------LLEALKDPDPEVRAAAAEALG-RIGDPE-----------AVPALIAALKDEDPEVRRAAAEA----------L 102

                        170       180       190
                 ....*....|....*....|....*....|...
gi 918410291 608 AVITDHGVVPLLSKLANTNNNKLRHHLAEAISR 640
Cdd:COG1413  103 GRLGDPAAVPALLEALKDPDWEVRRAAARALGR 135
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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