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Conserved domains on  [gi|938148789|ref|NP_001303246|]
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uncharacterized protein C2orf74 isoform 2 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF4642 super family cl21300
Domain of unknown function (DUF4642); This family of proteins is found in eukaryotes. Proteins ...
 1-115 5.22e-68

Domain of unknown function (DUF4642); This family of proteins is found in eukaryotes. Proteins in this family are typically between 115 and 196 amino acids in length.


The actual alignment was detected with superfamily member pfam15484:

Pssm-ID: 464742  Cd Length: 159  Bit Score: 201.58  E-value: 5.22e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 938148789    1 MQVMNLNVPMRPGILVQRQSKEVLATPLENRRDMEAEEENQINEKQEPENAGETGQEEDDgLQKIHTSVTRTPSVVESQK 80
Cdd:pfam15484  46 MHIINLNAPVRPGILVQRQSKEEVATSLENREDVEAEEEGKIKEKQEPENAGETGQEDED-LQKPPIPVTRTPSVVENQK 124

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 938148789   81 RPLKGVTFSREVIVVDLGNEYPTPRSYTREHKERK 115
Cdd:pfam15484 125 RPLKGVTFSREVIVVDLGNEYPTPRSYTREHKERK 159
 
Name Accession Description Interval E-value
DUF4642 pfam15484
Domain of unknown function (DUF4642); This family of proteins is found in eukaryotes. Proteins ...
 1-115 5.22e-68

Domain of unknown function (DUF4642); This family of proteins is found in eukaryotes. Proteins in this family are typically between 115 and 196 amino acids in length.


Pssm-ID: 464742  Cd Length: 159  Bit Score: 201.58  E-value: 5.22e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 938148789    1 MQVMNLNVPMRPGILVQRQSKEVLATPLENRRDMEAEEENQINEKQEPENAGETGQEEDDgLQKIHTSVTRTPSVVESQK 80
Cdd:pfam15484  46 MHIINLNAPVRPGILVQRQSKEEVATSLENREDVEAEEEGKIKEKQEPENAGETGQEDED-LQKPPIPVTRTPSVVENQK 124

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 938148789   81 RPLKGVTFSREVIVVDLGNEYPTPRSYTREHKERK 115
Cdd:pfam15484 125 RPLKGVTFSREVIVVDLGNEYPTPRSYTREHKERK 159
 
Name Accession Description Interval E-value
DUF4642 pfam15484
Domain of unknown function (DUF4642); This family of proteins is found in eukaryotes. Proteins ...
 1-115 5.22e-68

Domain of unknown function (DUF4642); This family of proteins is found in eukaryotes. Proteins in this family are typically between 115 and 196 amino acids in length.


Pssm-ID: 464742  Cd Length: 159  Bit Score: 201.58  E-value: 5.22e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 938148789    1 MQVMNLNVPMRPGILVQRQSKEVLATPLENRRDMEAEEENQINEKQEPENAGETGQEEDDgLQKIHTSVTRTPSVVESQK 80
Cdd:pfam15484  46 MHIINLNAPVRPGILVQRQSKEEVATSLENREDVEAEEEGKIKEKQEPENAGETGQEDED-LQKPPIPVTRTPSVVENQK 124

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 938148789   81 RPLKGVTFSREVIVVDLGNEYPTPRSYTREHKERK 115
Cdd:pfam15484 125 RPLKGVTFSREVIVVDLGNEYPTPRSYTREHKERK 159
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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