|
Name |
Accession |
Description |
Interval |
E-value |
| KRAB |
smart00349 |
krueppel associated box; |
1-32 |
1.13e-12 |
|
krueppel associated box;
Pssm-ID: 214630 [Multi-domain] Cd Length: 61 Bit Score: 62.61 E-value: 1.13e-12
10 20 30
....*....|....*....|....*....|..
gi 948549884 1 MLENYRNLVFLGIAVSKPDLITCLEQGKEPCN 32
Cdd:smart00349 30 MLENYSNLVSLGFQVPKPDLISQLEQGEEPWI 61
|
|
| COG5048 |
COG5048 |
FOG: Zn-finger [General function prediction only]; |
125-442 |
4.81e-10 |
|
FOG: Zn-finger [General function prediction only];
Pssm-ID: 227381 [Multi-domain] Cd Length: 467 Bit Score: 61.64 E-value: 4.81e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948549884 125 FSNSDRHKIRHTEKKTCKCKECGKSFCMLSQLTRHKRIHIRENSHKCEECGKAFNQSSALTRHKMTHTGEKPYKCEECGK 204
Cdd:COG5048 128 LPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPANSLSKDPSSNLSLLISSNVSTSIPSSSENSPLSS 207
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948549884 205 aFNRSSHLTQHKVIHTREKPYKCEECGKAFNRSSHITQHKRIHNREKPFKYDECCKAFKwSSALTTLTQHKRIHTGE--- 281
Cdd:COG5048 208 -SYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSL-PTASSQSSSPNESDSSSekg 285
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948549884 282 --KPYKCEECGKAFNQSSALTRHK--MIHTGE--KPFQCEE--CGKAFNRSSHLTQHKIIHTKEKPYKC--EECGKAFNR 351
Cdd:COG5048 286 fsLPIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSP 365
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948549884 352 SSH------LTKHKRIHTREKAYKCDEYCKAFNWSSALTTLtqHKIIHTGEKP--YKCEECGKAFNRSSYLIRHKIIHTG 423
Cdd:COG5048 366 LLNneppqsLQQYKDLKNDKKSETLSNSCIRNFKRDSNLSL--HIITHLSFRPynCKNPPCSKSFNRHYNLIPHKKIHTN 443
|
330
....*....|....*....
gi 948549884 424 EKPYKCEECGKaFNQSSHL 442
Cdd:COG5048 444 HAPLLCSILKS-FRRDLDL 461
|
|
| zf-H2C2_2 |
pfam13465 |
Zinc-finger double domain; |
271-295 |
6.10e-04 |
|
Zinc-finger double domain;
Pssm-ID: 463886 [Multi-domain] Cd Length: 26 Bit Score: 37.35 E-value: 6.10e-04
|
| zf-H2C2_2 |
pfam13465 |
Zinc-finger double domain; |
441-466 |
1.29e-03 |
|
Zinc-finger double domain;
Pssm-ID: 463886 [Multi-domain] Cd Length: 26 Bit Score: 36.20 E-value: 1.29e-03
10 20
....*....|....*....|....*.
gi 948549884 441 HLTQHKIIHTGEKPYKCEECGKAFNR 466
Cdd:pfam13465 1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
|
|
| SFP1 |
COG5189 |
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ... |
423-502 |
1.95e-03 |
|
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];
Pssm-ID: 227516 [Multi-domain] Cd Length: 423 Bit Score: 40.86 E-value: 1.95e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948549884 423 GEKPYKCE--ECGKAFNQSSHLTQHKiihtgekpyKCEECGKAFNRSSHLSQHKIIHTGEKPYKCEECGKPFNRFSYLTV 500
Cdd:COG5189 346 DGKPYKCPveGCNKKYKNQNGLKYHM---------LHGHQNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKY 416
|
..
gi 948549884 501 HK 502
Cdd:COG5189 417 HR 418
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| KRAB |
smart00349 |
krueppel associated box; |
1-32 |
1.13e-12 |
|
krueppel associated box;
Pssm-ID: 214630 [Multi-domain] Cd Length: 61 Bit Score: 62.61 E-value: 1.13e-12
10 20 30
....*....|....*....|....*....|..
gi 948549884 1 MLENYRNLVFLGIAVSKPDLITCLEQGKEPCN 32
Cdd:smart00349 30 MLENYSNLVSLGFQVPKPDLISQLEQGEEPWI 61
|
|
| COG5048 |
COG5048 |
FOG: Zn-finger [General function prediction only]; |
125-442 |
4.81e-10 |
|
FOG: Zn-finger [General function prediction only];
Pssm-ID: 227381 [Multi-domain] Cd Length: 467 Bit Score: 61.64 E-value: 4.81e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948549884 125 FSNSDRHKIRHTEKKTCKCKECGKSFCMLSQLTRHKRIHIRENSHKCEECGKAFNQSSALTRHKMTHTGEKPYKCEECGK 204
Cdd:COG5048 128 LPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPANSLSKDPSSNLSLLISSNVSTSIPSSSENSPLSS 207
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948549884 205 aFNRSSHLTQHKVIHTREKPYKCEECGKAFNRSSHITQHKRIHNREKPFKYDECCKAFKwSSALTTLTQHKRIHTGE--- 281
Cdd:COG5048 208 -SYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSL-PTASSQSSSPNESDSSSekg 285
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948549884 282 --KPYKCEECGKAFNQSSALTRHK--MIHTGE--KPFQCEE--CGKAFNRSSHLTQHKIIHTKEKPYKC--EECGKAFNR 351
Cdd:COG5048 286 fsLPIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSP 365
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948549884 352 SSH------LTKHKRIHTREKAYKCDEYCKAFNWSSALTTLtqHKIIHTGEKP--YKCEECGKAFNRSSYLIRHKIIHTG 423
Cdd:COG5048 366 LLNneppqsLQQYKDLKNDKKSETLSNSCIRNFKRDSNLSL--HIITHLSFRPynCKNPPCSKSFNRHYNLIPHKKIHTN 443
|
330
....*....|....*....
gi 948549884 424 EKPYKCEECGKaFNQSSHL 442
Cdd:COG5048 444 HAPLLCSILKS-FRRDLDL 461
|
|
| COG5048 |
COG5048 |
FOG: Zn-finger [General function prediction only]; |
167-531 |
7.54e-09 |
|
FOG: Zn-finger [General function prediction only];
Pssm-ID: 227381 [Multi-domain] Cd Length: 467 Bit Score: 58.17 E-value: 7.54e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948549884 167 NSHKCEECGKAFNQSSALTRHKMTHTGEKPYKC--EECGKAFNRSSHLTQHKVIHTREKPYKCE---------------- 228
Cdd:COG5048 32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSkslplsnskassssls 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948549884 229 ECGKAFNR-------SSHITQHKRIHNREKPFKYDECCKAFKWSSALTTLTQHKRIHtGEKPYKCEECGKAFNQSSALtr 301
Cdd:COG5048 112 SSSSNSNDnnllsshSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLH-PPLPANSLSKDPSSNLSLLI-- 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948549884 302 HKMIHTGEKPFQCEECGKAFNRSSHLTQHKIIHTKEKPYKCEECGKAF----NRSSHLTKHKRIHTREK-----AYKCDE 372
Cdd:COG5048 189 SSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSpkslLSQSPSSLSSSDSSSSAsesprSSLPTA 268
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948549884 373 YCKAFNWSSALTTLTQHKIihtgeKPYKCEECGKAFNRSSYLIRHK--IIHTGE--KPYKCEE--CGKAFNQSSHLTQHK 446
Cdd:COG5048 269 SSQSSSPNESDSSSEKGFS-----LPIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCPYslCGKLFSRNDALKRHI 343
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948549884 447 IIHTGEKPYKC--EECGKAFNRSS------HLSQHKIIHTGEKPYKCE-ECGKPFNRFSYLTVHKRIHAGENP--NKYEE 515
Cdd:COG5048 344 LLHTSISPAKEklLNSSSKFSPLLnneppqSLQQYKDLKNDKKSETLSnSCIRNFKRDSNLSLHIITHLSFRPynCKNPP 423
|
410
....*....|....*.
gi 948549884 516 CGKACNHSSNLTKHNS 531
Cdd:COG5048 424 CSKSFNRHYNLIPHKK 439
|
|
| SFP1 |
COG5189 |
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ... |
237-359 |
5.97e-05 |
|
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];
Pssm-ID: 227516 [Multi-domain] Cd Length: 423 Bit Score: 45.48 E-value: 5.97e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948549884 237 SSHITQHKRIHNREKPFKYDECCKAFKWSSALTTLTQHKRIHT-GEKPYKCE--ECGKAFNQSSALTRHkMIHTGEKPFQ 313
Cdd:COG5189 302 RGGISTGEMIDVRKLPCTNSSSNGKLAHGGERNIDTPSRMLKVkDGKPYKCPveGCNKKYKNQNGLKYH-MLHGHQNQKL 380
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 948549884 314 CEECGKafnrsshlTQHKIIHTKEKPYKCEECGKAFNRSSHLTKHK 359
Cdd:COG5189 381 HENPSP--------EKMNIFSAKDKPYRCEVCDKRYKNLNGLKYHR 418
|
|
| zf-H2C2_2 |
pfam13465 |
Zinc-finger double domain; |
271-295 |
6.10e-04 |
|
Zinc-finger double domain;
Pssm-ID: 463886 [Multi-domain] Cd Length: 26 Bit Score: 37.35 E-value: 6.10e-04
|
| zf-H2C2_2 |
pfam13465 |
Zinc-finger double domain; |
183-208 |
9.40e-04 |
|
Zinc-finger double domain;
Pssm-ID: 463886 [Multi-domain] Cd Length: 26 Bit Score: 36.58 E-value: 9.40e-04
10 20
....*....|....*....|....*.
gi 948549884 183 ALTRHKMTHTGEKPYKCEECGKAFNR 208
Cdd:pfam13465 1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
|
|
| zf-H2C2_2 |
pfam13465 |
Zinc-finger double domain; |
413-438 |
1.14e-03 |
|
Zinc-finger double domain;
Pssm-ID: 463886 [Multi-domain] Cd Length: 26 Bit Score: 36.58 E-value: 1.14e-03
10 20
....*....|....*....|....*.
gi 948549884 413 YLIRHKIIHTGEKPYKCEECGKAFNQ 438
Cdd:pfam13465 1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
|
|
| zf-H2C2_2 |
pfam13465 |
Zinc-finger double domain; |
441-466 |
1.29e-03 |
|
Zinc-finger double domain;
Pssm-ID: 463886 [Multi-domain] Cd Length: 26 Bit Score: 36.20 E-value: 1.29e-03
10 20
....*....|....*....|....*.
gi 948549884 441 HLTQHKIIHTGEKPYKCEECGKAFNR 466
Cdd:pfam13465 1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
|
|
| COG5048 |
COG5048 |
FOG: Zn-finger [General function prediction only]; |
336-469 |
1.77e-03 |
|
FOG: Zn-finger [General function prediction only];
Pssm-ID: 227381 [Multi-domain] Cd Length: 467 Bit Score: 40.83 E-value: 1.77e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948549884 336 KEKPYKCEECGKAFNRSSHLTKHKRIHTREKAYKCDeYCKAFNWSSALTTLTQHKIIHTGEKPYkcEECGKAFNRSSYLI 415
Cdd:COG5048 30 APRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCS-YSGCDKSFSRPLELSRHLRTHHNNPSD--LNSKSLPLSNSKAS 106
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 948549884 416 RHKIIHTGEKPYKCE-ECGKAFNQSSHLTQHKIIHTGEKPYKCEEcgKAFNRSSH 469
Cdd:COG5048 107 SSSLSSSSSNSNDNNlLSSHSLPPSSRDPQLPDLLSISNLRNNPL--PGNNSSSV 159
|
|
| zf-H2C2_2 |
pfam13465 |
Zinc-finger double domain; |
298-323 |
1.78e-03 |
|
Zinc-finger double domain;
Pssm-ID: 463886 [Multi-domain] Cd Length: 26 Bit Score: 35.81 E-value: 1.78e-03
10 20
....*....|....*....|....*.
gi 948549884 298 ALTRHKMIHTGEKPFQCEECGKAFNR 323
Cdd:pfam13465 1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
|
|
| SFP1 |
COG5189 |
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ... |
423-502 |
1.95e-03 |
|
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];
Pssm-ID: 227516 [Multi-domain] Cd Length: 423 Bit Score: 40.86 E-value: 1.95e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948549884 423 GEKPYKCE--ECGKAFNQSSHLTQHKiihtgekpyKCEECGKAFNRSSHLSQHKIIHTGEKPYKCEECGKPFNRFSYLTV 500
Cdd:COG5189 346 DGKPYKCPveGCNKKYKNQNGLKYHM---------LHGHQNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKY 416
|
..
gi 948549884 501 HK 502
Cdd:COG5189 417 HR 418
|
|
| zf-H2C2_2 |
pfam13465 |
Zinc-finger double domain; |
386-410 |
2.61e-03 |
|
Zinc-finger double domain;
Pssm-ID: 463886 [Multi-domain] Cd Length: 26 Bit Score: 35.42 E-value: 2.61e-03
|
| zf-H2C2_2 |
pfam13465 |
Zinc-finger double domain; |
326-351 |
2.63e-03 |
|
Zinc-finger double domain;
Pssm-ID: 463886 [Multi-domain] Cd Length: 26 Bit Score: 35.42 E-value: 2.63e-03
10 20
....*....|....*....|....*.
gi 948549884 326 HLTQHKIIHTKEKPYKCEECGKAFNR 351
Cdd:pfam13465 1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
|
|
| SFP1 |
COG5189 |
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ... |
395-474 |
3.31e-03 |
|
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];
Pssm-ID: 227516 [Multi-domain] Cd Length: 423 Bit Score: 40.09 E-value: 3.31e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948549884 395 GEKPYKCE--ECGKAFNRSSYLIRHKiihtgekpyKCEECGKAFNQSSHLTQHKIIHTGEKPYKCEECGKAFNRSSHLSQ 472
Cdd:COG5189 346 DGKPYKCPveGCNKKYKNQNGLKYHM---------LHGHQNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKY 416
|
..
gi 948549884 473 HK 474
Cdd:COG5189 417 HR 418
|
|
| zf-C2H2 |
pfam00096 |
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ... |
340-362 |
8.78e-03 |
|
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.
Pssm-ID: 395048 [Multi-domain] Cd Length: 23 Bit Score: 33.81 E-value: 8.78e-03
|
| zf-H2C2_2 |
pfam13465 |
Zinc-finger double domain; |
211-236 |
8.82e-03 |
|
Zinc-finger double domain;
Pssm-ID: 463886 [Multi-domain] Cd Length: 26 Bit Score: 33.88 E-value: 8.82e-03
10 20
....*....|....*....|....*.
gi 948549884 211 HLTQHKVIHTREKPYKCEECGKAFNR 236
Cdd:pfam13465 1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
|
|
|