NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1002819366|ref|NP_001307676|]
View 

envoplakin isoform 1 [Homo sapiens]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
SH3_10 pfam17902
SH3 domain; This entry represents an SH3 domain.
404-468 1.59e-26

SH3 domain; This entry represents an SH3 domain.


:

Pssm-ID: 407754  Cd Length: 65  Bit Score: 103.88  E-value: 1.59e-26
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1002819366  404 PLPQRRNPPQQPLHVDSICDWDSGEVQLLQGERYKLVDNTDPHAWVVQGPGGETKRAPAACFCIP 468
Cdd:pfam17902    1 PLKQRRSPVTRPIPVKALCDYKQGEVTVEKGEECTLLDNSDREKWKVQTSSGVEKLVPSVCFLIP 65
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
930-1473 1.13e-17

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 90.00  E-value: 1.13e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  930 AQAGRESEALKAQLEEERKRVARVQHELEAQRSQLLQLRTQrpLERLEEKEVVEFYRDPQLEGSLSRVKAQVEEEGKRRA 1009
Cdd:COG1196    242 EELEAELEELEAELEELEAELAELEAELEELRLELEELELE--LEEAQAEEYELLAELARLEQDIARLEERRRELEERLE 319
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1010 GLQADLEVAAQKVVQLESKRKTMQPHLLTKEVTQVErdpgLDSQAAQLRIQIQQLRGEDAVISARLEGLKKELLALEKRE 1089
Cdd:COG1196    320 ELEEELAELEEELEELEEELEELEEELEEAEEELEE----AEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAA 395
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1090 VDVKEKVVVKEVVKVEKNLEMVKAAQALRLQMEEDAARRKQAEEAVAKLQARIEDLERAISSVEpKVIVKEVKKVEQDPG 1169
Cdd:COG1196    396 AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEE-ALLELLAELLEEAAL 474
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1170 LLQESSRLRSLLEEERTKNATLARELSDLHSKYSVVEKQRPKVQLQ---ERVHEIFQVDPETEQEI-TRLKAKLQEMAGK 1245
Cdd:COG1196    475 LEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRglaGAVAVLIGVEAAYEAALeAALAAALQNIVVE 554
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1246 RSGVEKEVEKLLPDLEVLRA---QKPTVEYKEVTQEVVRHERSPEVLREIDRLKAQLNELVNSHGRSQEQLIRLQGERDE 1322
Cdd:COG1196    555 DDEVAAAAIEYLKAAKAGRAtflPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEA 634
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1323 WRRERAKVETKTVSKEVVRHEKDPVLEKEAERLRQEVREAAQKRRAAEDAVYELQSKRLLLERRKpEEKVVVQEVVVTQK 1402
Cdd:COG1196    635 ALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEAL-LAEEEEERELAEAE 713
                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1002819366 1403 DPKLREEHSRLSGSLDEEVGRRRQLELEVQQLRAGVEEQEGLLSFQEDRSkklAVERELRQLTLRIQELEK 1473
Cdd:COG1196    714 EERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLE---ELERELERLEREIEALGP 781
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
1348-1701 3.96e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 65.34  E-value: 3.96e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1348 LEKEAERLRQEvREAAQKRRAAEDAVYELQSKRLLLERRKpeekvvvqevvvtqkdpkLREEHSRLSGSLDEEVGRRRQL 1427
Cdd:COG1196    198 LERQLEPLERQ-AEKAERYRELKEELKELEAELLLLKLRE------------------LEAELEELEAELEELEAELEEL 258
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1428 ELEVQQLRAGVEEQegllsfqedRSKKLAVERELRQLTLRIQELEKRPPTVQEKIIMEEvvklEKDPDLEKSTEALRWDL 1507
Cdd:COG1196    259 EAELAELEAELEEL---------RLELEELELELEEAQAEEYELLAELARLEQDIARLE----ERRRELEERLEELEEEL 325
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1508 DQEKTQVTELNRECKNLQVQIDVLQKAKSQEKtiykEVIRVQKDRVLEDERARvwemLNRERTARQAREEEARRLRERID 1587
Cdd:COG1196    326 AELEEELEELEEELEELEEELEEAEEELEEAE----AELAEAEEALLEAEAEL----AEAEEELEELAEELLEALRAAAE 397
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1588 RAEtlgrtwsrEESELQRARDQADQECGRLQQELRALERQKQQQTLQLQEESKLLSQKTESERQKAAQRGQELSRLEAAI 1667
Cdd:COG1196    398 LAA--------QLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELL 469
                          330       340       350
                   ....*....|....*....|....*....|....
gi 1002819366 1668 LREKDQIYEKERTLRDLHAKVSREELSQETQTRE 1701
Cdd:COG1196    470 EEAALLEAALAELLEELAEAAARLLLLLEAEADY 503
Plectin pfam00681
Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous ...
1880-1918 5.73e-10

Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous pemphigoid antigen.


:

Pssm-ID: 459901  Cd Length: 39  Bit Score: 56.18  E-value: 5.73e-10
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 1002819366 1880 LLEAQAATGGIVDLLSRERYSVHKAMERGLIENTSTQRL 1918
Cdd:pfam00681    1 LLEAQAATGGIIDPVTGERLSVEEAVKRGLIDPETAQKL 39
PLEC smart00250
Plectin repeat;
1916-1953 8.42e-08

Plectin repeat;


:

Pssm-ID: 197605  Cd Length: 38  Bit Score: 49.79  E-value: 8.42e-08
                            10        20        30
                    ....*....|....*....|....*....|....*...
gi 1002819366  1916 QRLLNAQKAFTGIEDPVTKKRLSVGEAVQKGWMPRESV 1953
Cdd:smart00250    1 QRLLEAQSAIGGIIDPETGQKLSVEEALRRGLIDPETG 38
SPEC cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ...
228-415 9.81e-08

Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here


:

Pssm-ID: 238103 [Multi-domain]  Cd Length: 213  Bit Score: 54.76  E-value: 9.81e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  228 LYTHLQGCTRQLSALAEQQRRILQQDwsDLMADPAGVRREYEHFK--QHELLSQEQSVNQLEDDGERMVELRHPAVGPIQ 305
Cdd:cd00176      1 KLQQFLRDADELEAWLSEKEELLSST--DYGDDLESVEALLKKHEalEAELAAHEERVEALNELGEQLIEEGHPDAEEIQ 78
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  306 AHQEALKMEWQNFLNLCICQETQLQHVEDYRRFQEEADSVSQTLAKLNSNLDakySPAPGGPPGAPTELLQQLEAEEKRL 385
Cdd:cd00176     79 ERLEELNQRWEELRELAEERRQRLEEALDLQQFFRDADDLEQWLEEKEAALA---SEDLGKDLESVEELLKKHKELEEEL 155
                          170       180       190
                   ....*....|....*....|....*....|
gi 1002819366  386 avtERATGDLQRRSRDVAPLPQRRNPPQQP 415
Cdd:cd00176    156 ---EAHEPRLKSLNELAEELLEEGHPDADE 182
Plectin pfam00681
Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous ...
1957-1994 1.43e-07

Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous pemphigoid antigen.


:

Pssm-ID: 459901  Cd Length: 39  Bit Score: 49.25  E-value: 1.43e-07
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 1002819366 1957 LQVQHLTGGLIDPKRTGRIPIQQALLSGMISEELAQLL 1994
Cdd:pfam00681    2 LEAQAATGGIIDPVTGERLSVEEAVKRGLIDPETAQKL 39
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
651-1154 8.82e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 51.09  E-value: 8.82e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  651 EKAKAALDLERQIQDADRVIRGFEATLVQEApipAEPGALQERVSELQRQRRELLEQqtcVLRLHRALKASEHACAALQN 730
Cdd:COG1196    243 ELEAELEELEAELEELEAELAELEAELEELR---LELEELELELEEAQAEEYELLAE---LARLEQDIARLEERRRELEE 316
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  731 NFQEFCQDLPRQQRQVRALTDRYHAVGDQLDLREKVVQDAALTYQQFKN-----------CKDNLSSWLEHLPRSQVRPS 799
Cdd:COG1196    317 RLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEalleaeaelaeAEEELEELAEELLEALRAAA 396
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  800 DGPSQIAYKLQAQKRLTQEIQSRERDRATASHLSQALQAALQDYELQADTYRCSLEPTLAVSAPKRPRVAPLQESIQAQE 879
Cdd:COG1196    397 ELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLE 476
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  880 KNLAKAYTEVAAAQQQLLQQLEFARKM---------LEKKELSEDIRRTHDAKQGSESPAQAGRESEALKAQLEEERKRV 950
Cdd:COG1196    477 AALAELLEELAEAAARLLLLLEAEADYegflegvkaALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDD 556
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  951 ARVQHELEAQRSQLLQLRTQRPLERLEEKEVVEFYRDPQLEGSLSR-VKAQVEEEGKRRAGLQADLEVAAQKVVQLESKR 1029
Cdd:COG1196    557 EVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDlVASDLREADARYYVLGDTLLGRTLVAARLEAAL 636
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1030 KTMQPHLLTKEVTQVERDPGLDSQA-----------AQLRIQIQQLRGEDAVISARLEGLKKELLALEKREVDVKEKVVV 1098
Cdd:COG1196    637 RRAVTLAGRLREVTLEGEGGSAGGSltggsrrellaALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEER 716
                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1002819366 1099 KEVVKVEKNLEMVKAAQALRLQME---------EDAARRKQAEEAVAKLQARIEDLERAISSVEP 1154
Cdd:COG1196    717 LEEELEEEALEEQLEAEREELLEElleeeelleEEALEELPEPPDLEELERELERLEREIEALGP 781
Plectin pfam00681
Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous ...
1710-1738 1.39e-04

Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous pemphigoid antigen.


:

Pssm-ID: 459901  Cd Length: 39  Bit Score: 40.77  E-value: 1.39e-04
                           10        20
                   ....*....|....*....|....*....
gi 1002819366 1710 ILEPETGKDMSPYEAYKRGIIDRGQYLQL 1738
Cdd:pfam00681   11 IIDPVTGERLSVEEAVKRGLIDPETAQKL 39
PLEC smart00250
Plectin repeat;
1840-1877 2.70e-04

Plectin repeat;


:

Pssm-ID: 197605  Cd Length: 38  Bit Score: 40.16  E-value: 2.70e-04
                            10        20        30
                    ....*....|....*....|....*....|....*...
gi 1002819366  1840 LGLGDDSFPIAGIYDTTTDNKCSIKTAVAKNMLDPITG 1877
Cdd:smart00250    1 QRLLEAQSAIGGIIDPETGQKLSVEEALRRGLIDPETG 38
 
Name Accession Description Interval E-value
SH3_10 pfam17902
SH3 domain; This entry represents an SH3 domain.
404-468 1.59e-26

SH3 domain; This entry represents an SH3 domain.


Pssm-ID: 407754  Cd Length: 65  Bit Score: 103.88  E-value: 1.59e-26
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1002819366  404 PLPQRRNPPQQPLHVDSICDWDSGEVQLLQGERYKLVDNTDPHAWVVQGPGGETKRAPAACFCIP 468
Cdd:pfam17902    1 PLKQRRSPVTRPIPVKALCDYKQGEVTVEKGEECTLLDNSDREKWKVQTSSGVEKLVPSVCFLIP 65
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
930-1473 1.13e-17

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 90.00  E-value: 1.13e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  930 AQAGRESEALKAQLEEERKRVARVQHELEAQRSQLLQLRTQrpLERLEEKEVVEFYRDPQLEGSLSRVKAQVEEEGKRRA 1009
Cdd:COG1196    242 EELEAELEELEAELEELEAELAELEAELEELRLELEELELE--LEEAQAEEYELLAELARLEQDIARLEERRRELEERLE 319
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1010 GLQADLEVAAQKVVQLESKRKTMQPHLLTKEVTQVErdpgLDSQAAQLRIQIQQLRGEDAVISARLEGLKKELLALEKRE 1089
Cdd:COG1196    320 ELEEELAELEEELEELEEELEELEEELEEAEEELEE----AEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAA 395
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1090 VDVKEKVVVKEVVKVEKNLEMVKAAQALRLQMEEDAARRKQAEEAVAKLQARIEDLERAISSVEpKVIVKEVKKVEQDPG 1169
Cdd:COG1196    396 AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEE-ALLELLAELLEEAAL 474
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1170 LLQESSRLRSLLEEERTKNATLARELSDLHSKYSVVEKQRPKVQLQ---ERVHEIFQVDPETEQEI-TRLKAKLQEMAGK 1245
Cdd:COG1196    475 LEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRglaGAVAVLIGVEAAYEAALeAALAAALQNIVVE 554
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1246 RSGVEKEVEKLLPDLEVLRA---QKPTVEYKEVTQEVVRHERSPEVLREIDRLKAQLNELVNSHGRSQEQLIRLQGERDE 1322
Cdd:COG1196    555 DDEVAAAAIEYLKAAKAGRAtflPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEA 634
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1323 WRRERAKVETKTVSKEVVRHEKDPVLEKEAERLRQEVREAAQKRRAAEDAVYELQSKRLLLERRKpEEKVVVQEVVVTQK 1402
Cdd:COG1196    635 ALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEAL-LAEEEEERELAEAE 713
                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1002819366 1403 DPKLREEHSRLSGSLDEEVGRRRQLELEVQQLRAGVEEQEGLLSFQEDRSkklAVERELRQLTLRIQELEK 1473
Cdd:COG1196    714 EERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLE---ELERELERLEREIEALGP 781
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
934-1667 1.94e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 79.72  E-value: 1.94e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  934 RESEALKAQLEEERKRVARVQHELEAQRSQLLQLRTQrpLERLEEKEVVEFYRDPQLEGSLSRVKAQVEEEGKRRAGLQA 1013
Cdd:TIGR02168  260 AELQELEEKLEELRLEVSELEEEIEELQKELYALANE--ISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAE 337
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1014 DLEVAAQKVVQLESKRKTMQPHLLTKEVTQVERDPGLDSQAAQLRIQ---IQQLRGEDAVISARLEGLKKELLALEKREV 1090
Cdd:TIGR02168  338 ELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLrskVAQLELQIASLNNEIERLEARLERLEDRRE 417
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1091 DVKEKVVVKEVVKVEKNLEMVKAAQALRLQMEEDA-ARRKQAEEAVAKLQARIEDLERAISSVEPKvivkevkkveqdpg 1169
Cdd:TIGR02168  418 RLQQEIEELLKKLEEAELKELQAELEELEEELEELqEELERLEEALEELREELEEAEQALDAAERE-------------- 483
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1170 LLQESSRLRSlLEEERTKNATLARELSdlhskySVVEKQRPKVQLQERVHEIFQVDPETEQEI-TRLKAKLQEMAGKR-S 1247
Cdd:TIGR02168  484 LAQLQARLDS-LERLQENLEGFSEGVK------ALLKNQSGLSGILGVLSELISVDEGYEAAIeAALGGRLQAVVVENlN 556
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1248 GVEKEVEKLLPD---------LEVLRAQKPTVEYKEVTQEV-------VRHERSPEVLRE-----------IDRLKAQLN 1300
Cdd:TIGR02168  557 AAKKAIAFLKQNelgrvtflpLDSIKGTEIQGNDREILKNIegflgvaKDLVKFDPKLRKalsyllggvlvVDDLDNALE 636
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1301 ELVNSHGRsqEQLIRLQGERDEWRRERAKVETKTVSKEVVRhekdpvlEKEAERLRQEVREAAQKRRAAEDAVYELQSKr 1380
Cdd:TIGR02168  637 LAKKLRPG--YRIVTLDGDLVRPGGVITGGSAKTNSSILER-------RREIEELEEKIEELEEKIAELEKALAELRKE- 706
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1381 lLLERRKPEEKVVVQEVVVTQKDPKLREEHSRLSGSLDEEVGRRRQLELEVQQLRAGVEEQEGLLsfQEDRSKKLAVERE 1460
Cdd:TIGR02168  707 -LEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERL--EEAEEELAEAEAE 783
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1461 LRQLTLRIQELEKRPPTVQEKI-IMEEVVKLEKDP--DLEKSTEALRWDLDQEKTQVTELNRECKNLQVQIDVLQKA-KS 1536
Cdd:TIGR02168  784 IEELEAQIEQLKEELKALREALdELRAELTLLNEEaaNLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEiEE 863
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1537 QEKTIYKEVIRVQKdrvLEDERARVWEMLNRERTARQAREEEARRLRERIDRAEtlgrtwsREESELQRARDQADQECGR 1616
Cdd:TIGR02168  864 LEELIEELESELEA---LLNERASLEEALALLRSELEELSEELRELESKRSELR-------RELEELREKLAQLELRLEG 933
                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1002819366 1617 LQQELRALERQKQQQTLQLQEESKLLSQKTESERQKAAQRgqeLSRLEAAI 1667
Cdd:TIGR02168  934 LEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRR---LKRLENKI 981
PTZ00121 PTZ00121
MAEBL; Provisional
901-1684 1.45e-12

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 73.64  E-value: 1.45e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  901 EFARKMLEKKELSEDIRRTHDAKQGSEspaqAGRESEALKAqleEERKRVARVQHELEAQRSQllQLRTQRPLERLEE-K 979
Cdd:PTZ00121  1112 EEARKAEEAKKKAEDARKAEEARKAED----ARKAEEARKA---EDAKRVEIARKAEDARKAE--EARKAEDAKKAEAaR 1182
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  980 EVVEFYRDPQLEgslsrvkaQVEEEGKRRAGLQADLEVAAQKVVQLESKRKTMQphllTKEVTQVERDPGLDSQAAQLRI 1059
Cdd:PTZ00121  1183 KAEEVRKAEELR--------KAEDARKAEAARKAEEERKAEEARKAEDAKKAEA----VKKAEEAKKDAEEAKKAEEERN 1250
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1060 QIQQLRGEDAVIsARLEGLKKELLALEKREVDVKEKVVVKEVVKVEKNLEMVKAAQALRLQMEEdaarRKQAEEAVAKLQ 1139
Cdd:PTZ00121  1251 NEEIRKFEEARM-AHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEE----AKKADEAKKKAE 1325
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1140 ARIEDLERAISSVEPKvivkevkkveqdpgllQESSRLRSLLEEERTKNATLARELSDLHSKYSVVEKQRPKvQLQERVH 1219
Cdd:PTZ00121  1326 EAKKKADAAKKKAEEA----------------KKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKAD-AAKKKAE 1388
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1220 EIFQVDpeteqeitRLKAKLQEMAGKRSGVEKEVEkllpdlevlrAQKPTVEYKEVTQEVVRHE---RSPEVLREIDRLK 1296
Cdd:PTZ00121  1389 EKKKAD--------EAKKKAEEDKKKADELKKAAA----------AKKKADEAKKKAEEKKKADeakKKAEEAKKADEAK 1450
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1297 AQLNElvnshGRSQEQLIRLQGERDEWRRERAKVETKTVSKEVVRHEKdpvlekEAERLRQEVREAAQKRRAAEDAvYEL 1376
Cdd:PTZ00121  1451 KKAEE-----AKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAE------EAKKKADEAKKAAEAKKKADEA-KKA 1518
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1377 QSKRLLLERRKPEEKVVVQEVVVTQKDPKLREEHSRLSGSLDEEVGRRRQLELEVQQLRAGVEEQEGLLSFQEDRSKKLA 1456
Cdd:PTZ00121  1519 EEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVM 1598
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1457 VERElRQLTLRIQELEKRPptvQEKIIMEEVVKLEkdpDLEKSTEALRWDLDQEKTQVTELNRECKNLQVQIDVLQKAKS 1536
Cdd:PTZ00121  1599 KLYE-EEKKMKAEEAKKAE---EAKIKAEELKKAE---EEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAE 1671
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1537 QEKTIYKEVIRVQKDRVLEDERARVWEMLNRERTARQAREEEARRlreridRAETLGRTWSREESELQRARDQADQEcGR 1616
Cdd:PTZ00121  1672 EDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKK------KAEELKKAEEENKIKAEEAKKEAEED-KK 1744
                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1617 LQQELRALErqkqqqtlqlqEESKLLSQKTESERQKAAQRGQELSRLEAAILREKDQI--YEKERTLRDL 1684
Cdd:PTZ00121  1745 KAEEAKKDE-----------EEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKrrMEVDKKIKDI 1803
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
939-1710 1.91e-10

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 66.53  E-value: 1.91e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  939 LKAQLEEERKRVARVQHELEAQRSQLLQLRTQRPLERLEEKEVVEFYRDPQLEGSLSRVKAQVEEEGKRRAGLQADLEVA 1018
Cdd:pfam02463  167 LKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELL 246
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1019 AQKVVQLESKRKTMQPHllTKEVTQVERDPGLDSQaaqlriQIQQLRGEDAVISARLEGLKKELLALEKREVDVKEKVVV 1098
Cdd:pfam02463  247 RDEQEEIESSKQEIEKE--EEKLAQVLKENKEEEK------EKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKE 318
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1099 --KEVVKVEKNLEMVKAAQALRLQMEEDAARRKQAEEAVAKLQARIEDLERAISSVEPKVIVKEVKKVEQDPGLLQESSR 1176
Cdd:pfam02463  319 seKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELE 398
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1177 LRSLLEEERTKNATLAR----ELSDLHSKYSVVEKQRPKVQLQERVHEIFQVDPETEQEITRLKAKLQemagkrsgvEKE 1252
Cdd:pfam02463  399 LKSEEEKEAQLLLELARqledLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELE---------LKK 469
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1253 VEKLLPDLEVLraqkptveyKEVTQEVVRHERSPEVLREIDRLKAQLNELVNSHGRSQEQLIRLQGERDEWRRERAKVET 1332
Cdd:pfam02463  470 SEDLLKETQLV---------KLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVEN 540
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1333 KTVSKEVVRHEKDPVLEKEAERLRQEVREAAQKRRAAEDAVYELQSKRLLLERRKPEEKVVVQEVVVTQKDPKLREEHS- 1411
Cdd:pfam02463  541 YKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDk 620
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1412 -RLSGSLDEEVGRRRQLELEVQQLRAGVEEQEGLLSFQEDRSKKLAVERELRQLTLRIQELEKRPPTVQEKIIMEEVVKL 1490
Cdd:pfam02463  621 rAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLE 700
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1491 EKDPDLEKSTEALRWDLDQEKTQVTELNRECKNLQVQIDVLQKAKSQEKTIYKEvIRVQKDRVLEDERARVWEMLNRERT 1570
Cdd:pfam02463  701 IKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEK-SRLKKEEKEEEKSELSLKEKELAEE 779
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1571 ARQAREEEARRLRERIDRAETLGRTWSREESELQRARDQADQECGRLQQELRALERQKQQQTLQLQEESKLLSQKtESER 1650
Cdd:pfam02463  780 REKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEE-ELER 858
                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1651 QKAAQRGQELSRLEAAILREKDQIYEKERTLrDLHAKVSREELSQETQTRETNLSTKISI 1710
Cdd:pfam02463  859 LEEEITKEELLQELLLKEEELEEQKLKDELE-SKEEKEKEEKKELEEESQKLNLLEEKEN 917
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
1348-1701 3.96e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 65.34  E-value: 3.96e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1348 LEKEAERLRQEvREAAQKRRAAEDAVYELQSKRLLLERRKpeekvvvqevvvtqkdpkLREEHSRLSGSLDEEVGRRRQL 1427
Cdd:COG1196    198 LERQLEPLERQ-AEKAERYRELKEELKELEAELLLLKLRE------------------LEAELEELEAELEELEAELEEL 258
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1428 ELEVQQLRAGVEEQegllsfqedRSKKLAVERELRQLTLRIQELEKRPPTVQEKIIMEEvvklEKDPDLEKSTEALRWDL 1507
Cdd:COG1196    259 EAELAELEAELEEL---------RLELEELELELEEAQAEEYELLAELARLEQDIARLE----ERRRELEERLEELEEEL 325
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1508 DQEKTQVTELNRECKNLQVQIDVLQKAKSQEKtiykEVIRVQKDRVLEDERARvwemLNRERTARQAREEEARRLRERID 1587
Cdd:COG1196    326 AELEEELEELEEELEELEEELEEAEEELEEAE----AELAEAEEALLEAEAEL----AEAEEELEELAEELLEALRAAAE 397
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1588 RAEtlgrtwsrEESELQRARDQADQECGRLQQELRALERQKQQQTLQLQEESKLLSQKTESERQKAAQRGQELSRLEAAI 1667
Cdd:COG1196    398 LAA--------QLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELL 469
                          330       340       350
                   ....*....|....*....|....*....|....
gi 1002819366 1668 LREKDQIYEKERTLRDLHAKVSREELSQETQTRE 1701
Cdd:COG1196    470 EEAALLEAALAELLEELAEAAARLLLLLEAEADY 503
Plectin pfam00681
Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous ...
1880-1918 5.73e-10

Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous pemphigoid antigen.


Pssm-ID: 459901  Cd Length: 39  Bit Score: 56.18  E-value: 5.73e-10
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 1002819366 1880 LLEAQAATGGIVDLLSRERYSVHKAMERGLIENTSTQRL 1918
Cdd:pfam00681    1 LLEAQAATGGIIDPVTGERLSVEEAVKRGLIDPETAQKL 39
PLEC smart00250
Plectin repeat;
1916-1953 8.42e-08

Plectin repeat;


Pssm-ID: 197605  Cd Length: 38  Bit Score: 49.79  E-value: 8.42e-08
                            10        20        30
                    ....*....|....*....|....*....|....*...
gi 1002819366  1916 QRLLNAQKAFTGIEDPVTKKRLSVGEAVQKGWMPRESV 1953
Cdd:smart00250    1 QRLLEAQSAIGGIIDPETGQKLSVEEALRRGLIDPETG 38
SPEC cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ...
228-415 9.81e-08

Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here


Pssm-ID: 238103 [Multi-domain]  Cd Length: 213  Bit Score: 54.76  E-value: 9.81e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  228 LYTHLQGCTRQLSALAEQQRRILQQDwsDLMADPAGVRREYEHFK--QHELLSQEQSVNQLEDDGERMVELRHPAVGPIQ 305
Cdd:cd00176      1 KLQQFLRDADELEAWLSEKEELLSST--DYGDDLESVEALLKKHEalEAELAAHEERVEALNELGEQLIEEGHPDAEEIQ 78
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  306 AHQEALKMEWQNFLNLCICQETQLQHVEDYRRFQEEADSVSQTLAKLNSNLDakySPAPGGPPGAPTELLQQLEAEEKRL 385
Cdd:cd00176     79 ERLEELNQRWEELRELAEERRQRLEEALDLQQFFRDADDLEQWLEEKEAALA---SEDLGKDLESVEELLKKHKELEEEL 155
                          170       180       190
                   ....*....|....*....|....*....|
gi 1002819366  386 avtERATGDLQRRSRDVAPLPQRRNPPQQP 415
Cdd:cd00176    156 ---EAHEPRLKSLNELAEELLEEGHPDADE 182
Plectin pfam00681
Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous ...
1957-1994 1.43e-07

Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous pemphigoid antigen.


Pssm-ID: 459901  Cd Length: 39  Bit Score: 49.25  E-value: 1.43e-07
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 1002819366 1957 LQVQHLTGGLIDPKRTGRIPIQQALLSGMISEELAQLL 1994
Cdd:pfam00681    2 LEAQAATGGIIDPVTGERLSVEEAVKRGLIDPETAQKL 39
PLEC smart00250
Plectin repeat;
1878-1911 6.52e-07

Plectin repeat;


Pssm-ID: 197605  Cd Length: 38  Bit Score: 47.48  E-value: 6.52e-07
                            10        20        30
                    ....*....|....*....|....*....|....
gi 1002819366  1878 QKLLEAQAATGGIVDLLSRERYSVHKAMERGLIE 1911
Cdd:smart00250    1 QRLLEAQSAIGGIIDPETGQKLSVEEALRRGLID 34
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
651-1154 8.82e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 51.09  E-value: 8.82e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  651 EKAKAALDLERQIQDADRVIRGFEATLVQEApipAEPGALQERVSELQRQRRELLEQqtcVLRLHRALKASEHACAALQN 730
Cdd:COG1196    243 ELEAELEELEAELEELEAELAELEAELEELR---LELEELELELEEAQAEEYELLAE---LARLEQDIARLEERRRELEE 316
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  731 NFQEFCQDLPRQQRQVRALTDRYHAVGDQLDLREKVVQDAALTYQQFKN-----------CKDNLSSWLEHLPRSQVRPS 799
Cdd:COG1196    317 RLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEalleaeaelaeAEEELEELAEELLEALRAAA 396
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  800 DGPSQIAYKLQAQKRLTQEIQSRERDRATASHLSQALQAALQDYELQADTYRCSLEPTLAVSAPKRPRVAPLQESIQAQE 879
Cdd:COG1196    397 ELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLE 476
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  880 KNLAKAYTEVAAAQQQLLQQLEFARKM---------LEKKELSEDIRRTHDAKQGSESPAQAGRESEALKAQLEEERKRV 950
Cdd:COG1196    477 AALAELLEELAEAAARLLLLLEAEADYegflegvkaALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDD 556
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  951 ARVQHELEAQRSQLLQLRTQRPLERLEEKEVVEFYRDPQLEGSLSR-VKAQVEEEGKRRAGLQADLEVAAQKVVQLESKR 1029
Cdd:COG1196    557 EVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDlVASDLREADARYYVLGDTLLGRTLVAARLEAAL 636
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1030 KTMQPHLLTKEVTQVERDPGLDSQA-----------AQLRIQIQQLRGEDAVISARLEGLKKELLALEKREVDVKEKVVV 1098
Cdd:COG1196    637 RRAVTLAGRLREVTLEGEGGSAGGSltggsrrellaALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEER 716
                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1002819366 1099 KEVVKVEKNLEMVKAAQALRLQME---------EDAARRKQAEEAVAKLQARIEDLERAISSVEP 1154
Cdd:COG1196    717 LEEELEEEALEEQLEAEREELLEElleeeelleEEALEELPEPPDLEELERELERLEREIEALGP 781
SPEC smart00150
Spectrin repeats;
237-330 8.69e-05

Spectrin repeats;


Pssm-ID: 197544 [Multi-domain]  Cd Length: 101  Bit Score: 43.47  E-value: 8.69e-05
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366   237 RQLSALAEQQRRILQQDwsDLMADPAGVRREYEHFK--QHELLSQEQSVNQLEDDGERMVELRHPAVGPIQAHQEALKME 314
Cdd:smart00150    8 DELEAWLEEKEQLLASE--DLGKDLESVEALLKKHEafEAELEAHEERVEALNELGEQLIEEGHPDAEEIEERLEELNER 85
                            90
                    ....*....|....*.
gi 1002819366   315 WQNFLNLCICQETQLQ 330
Cdd:smart00150   86 WEELKELAEERRQKLE 101
Plectin pfam00681
Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous ...
1710-1738 1.39e-04

Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous pemphigoid antigen.


Pssm-ID: 459901  Cd Length: 39  Bit Score: 40.77  E-value: 1.39e-04
                           10        20
                   ....*....|....*....|....*....
gi 1002819366 1710 ILEPETGKDMSPYEAYKRGIIDRGQYLQL 1738
Cdd:pfam00681   11 IIDPVTGERLSVEEAVKRGLIDPETAQKL 39
PLEC smart00250
Plectin repeat;
1840-1877 2.70e-04

Plectin repeat;


Pssm-ID: 197605  Cd Length: 38  Bit Score: 40.16  E-value: 2.70e-04
                            10        20        30
                    ....*....|....*....|....*....|....*...
gi 1002819366  1840 LGLGDDSFPIAGIYDTTTDNKCSIKTAVAKNMLDPITG 1877
Cdd:smart00250    1 QRLLEAQSAIGGIIDPETGQKLSVEEALRRGLIDPETG 38
PLEC smart00250
Plectin repeat;
1954-1991 6.74e-04

Plectin repeat;


Pssm-ID: 197605  Cd Length: 38  Bit Score: 39.00  E-value: 6.74e-04
                            10        20        30
                    ....*....|....*....|....*....|....*...
gi 1002819366  1954 LPHLQVQHLTGGLIDPKRTGRIPIQQALLSGMISEELA 1991
Cdd:smart00250    1 QRLLEAQSAIGGIIDPETGQKLSVEEALRRGLIDPETG 38
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
1350-1740 1.77e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 43.57  E-value: 1.77e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1350 KEAERLRQEVREAAQKRR-AAEDAVYELQSKRLLLERRKPEEKVVVQEVVVTQKDPKLREEHS----RLSGSLDEEVGRR 1424
Cdd:pfam15921   88 KDLQRRLNESNELHEKQKfYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTvhelEAAKCLKEDMLED 167
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1425 RQLELEvqQLRAGVEEQEGLL--------SFQEDRSKKL----------------AVERELRQLTLRIQELEKRPPTVQE 1480
Cdd:pfam15921  168 SNTQIE--QLRKMMLSHEGVLqeirsilvDFEEASGKKIyehdsmstmhfrslgsAISKILRELDTEISYLKGRIFPVED 245
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1481 KIimeEVVKLEKDPDLE-------KSTEALRWDLDQEKTQVTE----LNRECKNLQVQIDVLQKAKSQEKTIYKevirvq 1549
Cdd:pfam15921  246 QL---EALKSESQNKIElllqqhqDRIEQLISEHEVEITGLTEkassARSQANSIQSQLEIIQEQARNQNSMYM------ 316
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1550 kdRVLEDERARVWEMLNRERTARQAREeearrlreriDRAETLGRTWSREESELQRAR---DQADQECG----RLQQELR 1622
Cdd:pfam15921  317 --RQLSDLESTVSQLRSELREAKRMYE----------DKIEELEKQLVLANSELTEARterDQFSQESGnlddQLQKLLA 384
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1623 ALERQKQQQTLQLQEESKLLSQKTESE------RQKAAQRGQELSRLEAAILREKDQIY-EKERTLRDLHAK-VSREELS 1694
Cdd:pfam15921  385 DLHKREKELSLEKEQNKRLWDRDTGNSitidhlRRELDDRNMEVQRLEALLKAMKSECQgQMERQMAAIQGKnESLEKVS 464
                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*.
gi 1002819366 1695 QETQTRETNLSTKISILEPETGKDMSpYEAYKRGIIDRGQYLQLQE 1740
Cdd:pfam15921  465 SLTAQLESTKEMLRKVVEELTAKKMT-LESSERTVSDLTASLQEKE 509
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
1407-1729 2.33e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.13  E-value: 2.33e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1407 REEHSRLSGSLDEEVGRRRQLElEVQQLRAGVEEQEGLLSFQEDRSKKLAVERELRqltLRIQELEKRPPTVQEKIIMEE 1486
Cdd:TIGR02169  156 RKIIDEIAGVAEFDRKKEKALE-ELEEVEENIERLDLIIDEKRQQLERLRREREKA---ERYQALLKEKREYEGYELLKE 231
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1487 VVKLEKD-PDLEKSTEALRWDLDQEKTQVTELNRECKNLQVQIDvlQKAKSQEKTIYKEVIRVQKD-RVLEDERARVWEM 1564
Cdd:TIGR02169  232 KEALERQkEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLE--ELNKKIKDLGEEEQLRVKEKiGELEAEIASLERS 309
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1565 LNRERTARQAREEEARRLRERIDRAETLGRTWSREESELQRARDQADQECGRLQQELRALERqkqqQTLQLQEESKLLSQ 1644
Cdd:TIGR02169  310 IAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRA----ELEEVDKEFAETRD 385
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1645 KTESERQKAAQRGQELSRLEAAILREKDQIYEKERTLRDLHAKVSR-EELSQETQTRETNLSTKISILEPE---TGKDMS 1720
Cdd:TIGR02169  386 ELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGiEAKINELEEEKEDKALEIKKQEWKleqLAADLS 465

                   ....*....
gi 1002819366 1721 PYEAYKRGI 1729
Cdd:TIGR02169  466 KYEQELYDL 474
PLEC smart00250
Plectin repeat;
1710-1735 5.32e-03

Plectin repeat;


Pssm-ID: 197605  Cd Length: 38  Bit Score: 36.31  E-value: 5.32e-03
                            10        20
                    ....*....|....*....|....*.
gi 1002819366  1710 ILEPETGKDMSPYEAYKRGIIDRGQY 1735
Cdd:smart00250   13 IIDPETGQKLSVEEALRRGLIDPETG 38
 
Name Accession Description Interval E-value
SH3_10 pfam17902
SH3 domain; This entry represents an SH3 domain.
404-468 1.59e-26

SH3 domain; This entry represents an SH3 domain.


Pssm-ID: 407754  Cd Length: 65  Bit Score: 103.88  E-value: 1.59e-26
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1002819366  404 PLPQRRNPPQQPLHVDSICDWDSGEVQLLQGERYKLVDNTDPHAWVVQGPGGETKRAPAACFCIP 468
Cdd:pfam17902    1 PLKQRRSPVTRPIPVKALCDYKQGEVTVEKGEECTLLDNSDREKWKVQTSSGVEKLVPSVCFLIP 65
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
930-1473 1.13e-17

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 90.00  E-value: 1.13e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  930 AQAGRESEALKAQLEEERKRVARVQHELEAQRSQLLQLRTQrpLERLEEKEVVEFYRDPQLEGSLSRVKAQVEEEGKRRA 1009
Cdd:COG1196    242 EELEAELEELEAELEELEAELAELEAELEELRLELEELELE--LEEAQAEEYELLAELARLEQDIARLEERRRELEERLE 319
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1010 GLQADLEVAAQKVVQLESKRKTMQPHLLTKEVTQVErdpgLDSQAAQLRIQIQQLRGEDAVISARLEGLKKELLALEKRE 1089
Cdd:COG1196    320 ELEEELAELEEELEELEEELEELEEELEEAEEELEE----AEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAA 395
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1090 VDVKEKVVVKEVVKVEKNLEMVKAAQALRLQMEEDAARRKQAEEAVAKLQARIEDLERAISSVEpKVIVKEVKKVEQDPG 1169
Cdd:COG1196    396 AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEE-ALLELLAELLEEAAL 474
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1170 LLQESSRLRSLLEEERTKNATLARELSDLHSKYSVVEKQRPKVQLQ---ERVHEIFQVDPETEQEI-TRLKAKLQEMAGK 1245
Cdd:COG1196    475 LEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRglaGAVAVLIGVEAAYEAALeAALAAALQNIVVE 554
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1246 RSGVEKEVEKLLPDLEVLRA---QKPTVEYKEVTQEVVRHERSPEVLREIDRLKAQLNELVNSHGRSQEQLIRLQGERDE 1322
Cdd:COG1196    555 DDEVAAAAIEYLKAAKAGRAtflPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEA 634
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1323 WRRERAKVETKTVSKEVVRHEKDPVLEKEAERLRQEVREAAQKRRAAEDAVYELQSKRLLLERRKpEEKVVVQEVVVTQK 1402
Cdd:COG1196    635 ALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEAL-LAEEEEERELAEAE 713
                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1002819366 1403 DPKLREEHSRLSGSLDEEVGRRRQLELEVQQLRAGVEEQEGLLSFQEDRSkklAVERELRQLTLRIQELEK 1473
Cdd:COG1196    714 EERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLE---ELERELERLEREIEALGP 781
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
937-1520 1.37e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 86.53  E-value: 1.37e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  937 EALKaQLEEERKRVARVQ---HELEAQRSQL----------LQLRtqrplERLEEKEVVE-FYRDPQLEGSLSRVKAQVE 1002
Cdd:COG1196    176 EAER-KLEATEENLERLEdilGELERQLEPLerqaekaeryRELK-----EELKELEAELlLLKLRELEAELEELEAELE 249
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1003 EEGKRRAGLQADLEVAAQKVVQLESKRKTMQphLLTKEVTQVERDpgLDSQAAQLRIQIQQLRGEDAVISARLEGLKKEL 1082
Cdd:COG1196    250 ELEAELEELEAELAELEAELEELRLELEELE--LELEEAQAEEYE--LLAELARLEQDIARLEERRRELEERLEELEEEL 325
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1083 LALEKREVDVKEKVVVKEVVKVEKNLEMVKAAQALRLQMEEDAARRKQAEEAVAKLQARIEDLERAISSVEPKVIVKEVK 1162
Cdd:COG1196    326 AELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEEL 405
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1163 KVEQDpGLLQESSRLRSLLEEERTKNATLARELSDLHSKYS-----VVEKQRPKVQLQERVHEIFQVDPETEQEITRLKA 1237
Cdd:COG1196    406 EEAEE-ALLERLERLEEELEELEEALAELEEEEEEEEEALEeaaeeEAELEEEEEALLELLAELLEEAALLEAALAELLE 484
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1238 KLQEMAGKRSGVEKEVEKLLPDLEVLRAQKPTVEYKEVTQEVVRHERSPEVLRE--IDRLKAQLNELVNSHGRSQEQLIR 1315
Cdd:COG1196    485 ELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAalEAALAAALQNIVVEDDEVAAAAIE 564
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1316 LQGERDEWRRERAKVETKTVSKEVVRHEKDPVLEKEAERLRQEVREAAQKRRAAEDAVYELQSKRLLLERRKPEEKVVVQ 1395
Cdd:COG1196    565 YLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAG 644
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1396 EVVVTQKD-----PKLREEHSRLSGSLDEEVGRRRQLELEVQQLRAGVEEQEGLLSFQEDRSKKLAVERE-LRQLTLRIQ 1469
Cdd:COG1196    645 RLREVTLEgeggsAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEeRLEEELEEE 724
                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1002819366 1470 ELEKRPPTVQEKIIMEEVVKLEKDPDLEKSTEALRWDLDQEKTQVTELNRE 1520
Cdd:COG1196    725 ALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLERE 775
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
934-1667 1.94e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 79.72  E-value: 1.94e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  934 RESEALKAQLEEERKRVARVQHELEAQRSQLLQLRTQrpLERLEEKEVVEFYRDPQLEGSLSRVKAQVEEEGKRRAGLQA 1013
Cdd:TIGR02168  260 AELQELEEKLEELRLEVSELEEEIEELQKELYALANE--ISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAE 337
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1014 DLEVAAQKVVQLESKRKTMQPHLLTKEVTQVERDPGLDSQAAQLRIQ---IQQLRGEDAVISARLEGLKKELLALEKREV 1090
Cdd:TIGR02168  338 ELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLrskVAQLELQIASLNNEIERLEARLERLEDRRE 417
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1091 DVKEKVVVKEVVKVEKNLEMVKAAQALRLQMEEDA-ARRKQAEEAVAKLQARIEDLERAISSVEPKvivkevkkveqdpg 1169
Cdd:TIGR02168  418 RLQQEIEELLKKLEEAELKELQAELEELEEELEELqEELERLEEALEELREELEEAEQALDAAERE-------------- 483
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1170 LLQESSRLRSlLEEERTKNATLARELSdlhskySVVEKQRPKVQLQERVHEIFQVDPETEQEI-TRLKAKLQEMAGKR-S 1247
Cdd:TIGR02168  484 LAQLQARLDS-LERLQENLEGFSEGVK------ALLKNQSGLSGILGVLSELISVDEGYEAAIeAALGGRLQAVVVENlN 556
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1248 GVEKEVEKLLPD---------LEVLRAQKPTVEYKEVTQEV-------VRHERSPEVLRE-----------IDRLKAQLN 1300
Cdd:TIGR02168  557 AAKKAIAFLKQNelgrvtflpLDSIKGTEIQGNDREILKNIegflgvaKDLVKFDPKLRKalsyllggvlvVDDLDNALE 636
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1301 ELVNSHGRsqEQLIRLQGERDEWRRERAKVETKTVSKEVVRhekdpvlEKEAERLRQEVREAAQKRRAAEDAVYELQSKr 1380
Cdd:TIGR02168  637 LAKKLRPG--YRIVTLDGDLVRPGGVITGGSAKTNSSILER-------RREIEELEEKIEELEEKIAELEKALAELRKE- 706
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1381 lLLERRKPEEKVVVQEVVVTQKDPKLREEHSRLSGSLDEEVGRRRQLELEVQQLRAGVEEQEGLLsfQEDRSKKLAVERE 1460
Cdd:TIGR02168  707 -LEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERL--EEAEEELAEAEAE 783
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1461 LRQLTLRIQELEKRPPTVQEKI-IMEEVVKLEKDP--DLEKSTEALRWDLDQEKTQVTELNRECKNLQVQIDVLQKA-KS 1536
Cdd:TIGR02168  784 IEELEAQIEQLKEELKALREALdELRAELTLLNEEaaNLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEiEE 863
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1537 QEKTIYKEVIRVQKdrvLEDERARVWEMLNRERTARQAREEEARRLRERIDRAEtlgrtwsREESELQRARDQADQECGR 1616
Cdd:TIGR02168  864 LEELIEELESELEA---LLNERASLEEALALLRSELEELSEELRELESKRSELR-------RELEELREKLAQLELRLEG 933
                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1002819366 1617 LQQELRALERQKQQQTLQLQEESKLLSQKTESERQKAAQRgqeLSRLEAAI 1667
Cdd:TIGR02168  934 LEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRR---LKRLENKI 981
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
930-1724 2.10e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 76.26  E-value: 2.10e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  930 AQAGRESEALKAQLEEERKRVARVQHELEAQRSQLLQLRTQRP-----LERLEEKEVVEFY----RDPQLEGSLSRVKAQ 1000
Cdd:TIGR02169  166 AEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREkaeryQALLKEKREYEGYellkEKEALERQKEAIERQ 245
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1001 VEEEGKRRAGLQADLEVAAQKVVQLESKRKTmqphlLTKEVtqverDPGLDSQAAQLRIQIQQLRGEDAVISARLEglkk 1080
Cdd:TIGR02169  246 LASLEEELEKLTEEISELEKRLEEIEQLLEE-----LNKKI-----KDLGEEEQLRVKEKIGELEAEIASLERSIA---- 311
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1081 ellalekrevdvkekvvvkevvkveknlemvkaaqALRLQMEEDAARRKQAEEAVAKLQARIEDLERAISSVEPKVIVKE 1160
Cdd:TIGR02169  312 -----------------------------------EKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLT 356
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1161 VKKVEqdpgLLQESSRLRSLLEEERTKNATLARELSDLHSKYSVV-----EKQRPKVQLQERVHEIFQVDPETEQEITRL 1235
Cdd:TIGR02169  357 EEYAE----LKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLkreinELKRELDRLQEELQRLSEELADLNAAIAGI 432
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1236 KAKLQEMAGKRSGVEKEVEKLLPDLEVLRAQKPTVEYK----EVTQEVVRHERSpEVLREIDRLKAQLNELVNS--HGRS 1309
Cdd:TIGR02169  433 EAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQElydlKEEYDRVEKELS-KLQRELAEAEAQARASEERvrGGRA 511
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1310 QEQLIR--------LQGERDEWRRERAK-VETKTVSK-EVVRHEKDPVLEKEAERLRQEvreaaQKRRAAEDAVYELQSK 1379
Cdd:TIGR02169  512 VEEVLKasiqgvhgTVAQLGSVGERYATaIEVAAGNRlNNVVVEDDAVAKEAIELLKRR-----KAGRATFLPLNKMRDE 586
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1380 RLLLERRKPEEKVVVQEVVVTQkDPKLREEHSRLSGSL----DEEVGRRRQLELEVQQLRAGVEEQEGLLSFQEDRSKKL 1455
Cdd:TIGR02169  587 RRDLSILSEDGVIGFAVDLVEF-DPKYEPAFKYVFGDTlvveDIEAARRLMGKYRMVTLEGELFEKSGAMTGGSRAPRGG 665
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1456 AV-----ERELRQLTLRIQELEKrpptvQEKIIMEEVVKLEKD--------PDLEKSTEALRWDLDQEKTQVTELNRECK 1522
Cdd:TIGR02169  666 ILfsrsePAELQRLRERLEGLKR-----ELSSLQSELRRIENRldelsqelSDASRKIGEIEKEIEQLEQEEEKLKERLE 740
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1523 NLQVQIDVLQKAKSQEKTIYKEVIRV--QKDRVLEDERARVWEMLNRERTAR-QAREEEARRLRERIDRAETLGRTWSRE 1599
Cdd:TIGR02169  741 ELEEDLSSLEQEIENVKSELKELEARieELEEDLHKLEEALNDLEARLSHSRiPEIQAELSKLEEEVSRIEARLREIEQK 820
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1600 ESELQRARDQADQECGRLQQELRALE-RQKQQQTLQLQEESKLLSQKTESERQKAAQR--GQELSRLEAAILREKDQIYE 1676
Cdd:TIGR02169  821 LNRLTLEKEYLEKEIQELQEQRIDLKeQIKSIEKEIENLNGKKEELEEELEELEAALRdlESRLGDLKKERDELEAQLRE 900
                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*....
gi 1002819366 1677 KERTLRDLHAKVSREELSQ-ETQTRETNLSTKISILEPETGKDMSPYEA 1724
Cdd:TIGR02169  901 LERKIEELEAQIEKKRKRLsELKAKLEALEEELSEIEDPKGEDEEIPEE 949
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
1178-1704 8.87e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 73.82  E-value: 8.87e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1178 RSLLEEERTKNATL-ARELSDLHSKYSVVEKQRPKVQLQERvheifqvdpETEQEITRLKAKLQEMAGKRSGVEKEVEKL 1256
Cdd:COG1196    216 RELKEELKELEAELlLLKLRELEAELEELEAELEELEAELE---------ELEAELAELEAELEELRLELEELELELEEA 286
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1257 LPDLEVLRAQKPTVEykevTQEVVRHERSPEVLREIDRLKAQLNELVNSHGRSQEQLIRLQGERDEWRRERAKVETKTVS 1336
Cdd:COG1196    287 QAEEYELLAELARLE----QDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAE 362
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1337 KEVVRHEKDPVLEKEAERLRQEVREAAQKRRAAEDAVYELQSKRLLLERRKP-EEKVVVQEVVVTQKDPKLREEHSRLSG 1415
Cdd:COG1196    363 AEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLErLERLEEELEELEEALAELEEEEEEEEE 442
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1416 SLDEEVGRRRQLELEVQQLRAGVEEQEGLLSFQEDRSKKLAVERELRQLTLRIQELEKRPPTVQEKIIMEEVVKLEKDPD 1495
Cdd:COG1196    443 ALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGL 522
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1496 LEKSTEALRWDLDQEKTQVTELNRECKNLQVQIDvlQKAKSQEKTIYKEVIRVQKDRVLEDERARVWEMLNRERTARQAR 1575
Cdd:COG1196    523 AGAVAVLIGVEAAYEAALEAALAAALQNIVVEDD--EVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAA 600
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1576 EEEARRLRERIDRAETLGRTWSREESELQRARDQADQECGRLQQELRALERQKQQQTLQLQEESKLLSQKTESERQKAAQ 1655
Cdd:COG1196    601 VDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAE 680
                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*....
gi 1002819366 1656 RGQELSRLEAAILREKDQIYEKERTLRDLHAKVSREELSQETQTRETNL 1704
Cdd:COG1196    681 LEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQ 729
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
968-1712 1.30e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 73.55  E-value: 1.30e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  968 RTQRPLERLEEkeVVEfyrdpQLEGSLSRVKAQVEEEGK----RRAGLQADLEVAAQKVVQLESKRKTMQpHLLTKEVTQ 1043
Cdd:TIGR02168  183 RTRENLDRLED--ILN-----ELERQLKSLERQAEKAERykelKAELRELELALLVLRLEELREELEELQ-EELKEAEEE 254
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1044 VERdpgLDSQAAQLRIQIQQLRGEDAVISARLEGLKKELLAL--EKREVDVKEKVVVKEVVKVEKNLEMVKAAQALRLQM 1121
Cdd:TIGR02168  255 LEE---LTAELQELEEKLEELRLEVSELEEEIEELQKELYALanEISRLEQQKQILRERLANLERQLEELEAQLEELESK 331
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1122 -EEDAARRKQAEEAVAKLQARIEDLERAISSVEPKVIVKEVKKVEQDPGLLQESSRLRSLLEEERTKNATLARELSDLHs 1200
Cdd:TIGR02168  332 lDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLE- 410
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1201 kysvvekqrpkvQLQERVHEIFQVDPETEQEITRlkAKLQEMAGKRSGVEKEVEKLLPDLEVLRAQKPTVEykevtqevv 1280
Cdd:TIGR02168  411 ------------RLEDRRERLQQEIEELLKKLEE--AELKELQAELEELEEELEELQEELERLEEALEELR--------- 467
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1281 rhERSPEVLREIDRLKAQLNELVNSHGRSQEQLIRLQGERDEWRRERAKVETKT----VSKEVVRHEKDPVLEKEA---E 1353
Cdd:TIGR02168  468 --EELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSgilgVLSELISVDEGYEAAIEAalgG 545
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1354 RLRQEVREAAQkrrAAEDAVYELQSKRL-------------------LLERRKPEEKVVVQEVVVTQKDPKLRE------ 1408
Cdd:TIGR02168  546 RLQAVVVENLN---AAKKAIAFLKQNELgrvtflpldsikgteiqgnDREILKNIEGFLGVAKDLVKFDPKLRKalsyll 622
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1409 EHSRLSGSLDEEVGRRRQLE-------LEVQQLRAGveeqeGLLSFQEDR--SKKLAVERELRQLTLRIQELEkrpptVQ 1479
Cdd:TIGR02168  623 GGVLVVDDLDNALELAKKLRpgyrivtLDGDLVRPG-----GVITGGSAKtnSSILERRREIEELEEKIEELE-----EK 692
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1480 EKIIMEEVVklekdpDLEKSTEALRWDLDQEKTQVTELNRECKNLQVQidvLQKAKSQEKTIYKEVIRVQKDRV-LEDER 1558
Cdd:TIGR02168  693 IAELEKALA------ELRKELEELEEELEQLRKELEELSRQISALRKD---LARLEAEVEQLEERIAQLSKELTeLEAEI 763
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1559 ARVWEMLNRERTARQAREEEARRLRERIDRAETLGRTWSREESELQRARDQADQECGRLQQELRALERQKQQQTLQLQEE 1638
Cdd:TIGR02168  764 EELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDL 843
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1639 SKLLSQKTESERQKAAQRGQ-----------------ELSRLEAAILREKDQIYEKERTLRDLHAKVSR-EELSQETQTR 1700
Cdd:TIGR02168  844 EEQIEELSEDIESLAAEIEEleelieeleseleallnERASLEEALALLRSELEELSEELRELESKRSElRRELEELREK 923
                          810
                   ....*....|..
gi 1002819366 1701 ETNLSTKISILE 1712
Cdd:TIGR02168  924 LAQLELRLEGLE 935
PTZ00121 PTZ00121
MAEBL; Provisional
901-1684 1.45e-12

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 73.64  E-value: 1.45e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  901 EFARKMLEKKELSEDIRRTHDAKQGSEspaqAGRESEALKAqleEERKRVARVQHELEAQRSQllQLRTQRPLERLEE-K 979
Cdd:PTZ00121  1112 EEARKAEEAKKKAEDARKAEEARKAED----ARKAEEARKA---EDAKRVEIARKAEDARKAE--EARKAEDAKKAEAaR 1182
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  980 EVVEFYRDPQLEgslsrvkaQVEEEGKRRAGLQADLEVAAQKVVQLESKRKTMQphllTKEVTQVERDPGLDSQAAQLRI 1059
Cdd:PTZ00121  1183 KAEEVRKAEELR--------KAEDARKAEAARKAEEERKAEEARKAEDAKKAEA----VKKAEEAKKDAEEAKKAEEERN 1250
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1060 QIQQLRGEDAVIsARLEGLKKELLALEKREVDVKEKVVVKEVVKVEKNLEMVKAAQALRLQMEEdaarRKQAEEAVAKLQ 1139
Cdd:PTZ00121  1251 NEEIRKFEEARM-AHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEE----AKKADEAKKKAE 1325
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1140 ARIEDLERAISSVEPKvivkevkkveqdpgllQESSRLRSLLEEERTKNATLARELSDLHSKYSVVEKQRPKvQLQERVH 1219
Cdd:PTZ00121  1326 EAKKKADAAKKKAEEA----------------KKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKAD-AAKKKAE 1388
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1220 EIFQVDpeteqeitRLKAKLQEMAGKRSGVEKEVEkllpdlevlrAQKPTVEYKEVTQEVVRHE---RSPEVLREIDRLK 1296
Cdd:PTZ00121  1389 EKKKAD--------EAKKKAEEDKKKADELKKAAA----------AKKKADEAKKKAEEKKKADeakKKAEEAKKADEAK 1450
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1297 AQLNElvnshGRSQEQLIRLQGERDEWRRERAKVETKTVSKEVVRHEKdpvlekEAERLRQEVREAAQKRRAAEDAvYEL 1376
Cdd:PTZ00121  1451 KKAEE-----AKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAE------EAKKKADEAKKAAEAKKKADEA-KKA 1518
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1377 QSKRLLLERRKPEEKVVVQEVVVTQKDPKLREEHSRLSGSLDEEVGRRRQLELEVQQLRAGVEEQEGLLSFQEDRSKKLA 1456
Cdd:PTZ00121  1519 EEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVM 1598
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1457 VERElRQLTLRIQELEKRPptvQEKIIMEEVVKLEkdpDLEKSTEALRWDLDQEKTQVTELNRECKNLQVQIDVLQKAKS 1536
Cdd:PTZ00121  1599 KLYE-EEKKMKAEEAKKAE---EAKIKAEELKKAE---EEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAE 1671
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1537 QEKTIYKEVIRVQKDRVLEDERARVWEMLNRERTARQAREEEARRlreridRAETLGRTWSREESELQRARDQADQEcGR 1616
Cdd:PTZ00121  1672 EDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKK------KAEELKKAEEENKIKAEEAKKEAEED-KK 1744
                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1617 LQQELRALErqkqqqtlqlqEESKLLSQKTESERQKAAQRGQELSRLEAAILREKDQI--YEKERTLRDL 1684
Cdd:PTZ00121  1745 KAEEAKKDE-----------EEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKrrMEVDKKIKDI 1803
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
934-1595 8.15e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 70.74  E-value: 8.15e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  934 RESEALKAQLEEERKRVARVQHELEAQRSQLLQLRTQRPlerleekevvefyrdpQLEGSLSRVKAQVEEEGKRRAGLQA 1013
Cdd:COG1196    225 LEAELLLLKLRELEAELEELEAELEELEAELEELEAELA----------------ELEAELEELRLELEELELELEEAQA 288
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1014 DLEVAAQKVVQLESKRKTmqphlltkevtQVERDPGLDSQAAQLRIQIQQLRGEDAVISARLEGLKKELLALEKREVDVK 1093
Cdd:COG1196    289 EEYELLAELARLEQDIAR-----------LEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAE 357
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1094 EKVVVKEVVKveknLEMVKAAQALRLQMEEDAARRKQAEEAVAKLQARIEDLERAISSvepkvivkevkkveqdpgLLQE 1173
Cdd:COG1196    358 AELAEAEEAL----LEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEA------------------LLER 415
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1174 SSRLRSLLEEERTKNATLARELSDLHSKYS-----VVEKQRPKVQLQERVHEIFQVDPETEQEITRLKAKLQEMAGKRSG 1248
Cdd:COG1196    416 LERLEEELEELEEALAELEEEEEEEEEALEeaaeeEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLL 495
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1249 VEKEVEKLLPDLEVLRAQKPTVEYKEVTQEVVRHERSPEVLRE--IDRLKAQLNELVNSHGRSQEQLIRLQGERDEWRRE 1326
Cdd:COG1196    496 LLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAalEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRAT 575
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1327 RAKVETKTVSKEVVRHEKDPVLEKEAERLRQEVREAAQKRRAAEDAVYELQSKRLLLERRKPEEKVVVQEVVVTQKD--- 1403
Cdd:COG1196    576 FLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEgeg 655
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1404 --PKLREEHSRLSGSLDEEVGRRRQLELEVQQLRAGVEEQEGLLSFQEDRSKKLAVERE-LRQLTLRIQELEKRPPTVQE 1480
Cdd:COG1196    656 gsAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEeRLEEELEEEALEEQLEAERE 735
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1481 KIIMEEVVKLEKDPDLEKSTEALRWDLDQEKTQVTELNRECKNL-QVQIDVLQKAKSQEKTiyKEVIRVQKDrVLEDERA 1559
Cdd:COG1196    736 ELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALgPVNLLAIEEYEELEER--YDFLSEQRE-DLEEARE 812
                          650       660       670
                   ....*....|....*....|....*....|....*.
gi 1002819366 1560 RvwemlnrertarqareeearrLRERIDRAETLGRT 1595
Cdd:COG1196    813 T---------------------LEEAIEEIDRETRE 827
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
939-1710 1.91e-10

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 66.53  E-value: 1.91e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  939 LKAQLEEERKRVARVQHELEAQRSQLLQLRTQRPLERLEEKEVVEFYRDPQLEGSLSRVKAQVEEEGKRRAGLQADLEVA 1018
Cdd:pfam02463  167 LKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELL 246
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1019 AQKVVQLESKRKTMQPHllTKEVTQVERDPGLDSQaaqlriQIQQLRGEDAVISARLEGLKKELLALEKREVDVKEKVVV 1098
Cdd:pfam02463  247 RDEQEEIESSKQEIEKE--EEKLAQVLKENKEEEK------EKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKE 318
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1099 --KEVVKVEKNLEMVKAAQALRLQMEEDAARRKQAEEAVAKLQARIEDLERAISSVEPKVIVKEVKKVEQDPGLLQESSR 1176
Cdd:pfam02463  319 seKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELE 398
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1177 LRSLLEEERTKNATLAR----ELSDLHSKYSVVEKQRPKVQLQERVHEIFQVDPETEQEITRLKAKLQemagkrsgvEKE 1252
Cdd:pfam02463  399 LKSEEEKEAQLLLELARqledLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELE---------LKK 469
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1253 VEKLLPDLEVLraqkptveyKEVTQEVVRHERSPEVLREIDRLKAQLNELVNSHGRSQEQLIRLQGERDEWRRERAKVET 1332
Cdd:pfam02463  470 SEDLLKETQLV---------KLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVEN 540
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1333 KTVSKEVVRHEKDPVLEKEAERLRQEVREAAQKRRAAEDAVYELQSKRLLLERRKPEEKVVVQEVVVTQKDPKLREEHS- 1411
Cdd:pfam02463  541 YKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDk 620
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1412 -RLSGSLDEEVGRRRQLELEVQQLRAGVEEQEGLLSFQEDRSKKLAVERELRQLTLRIQELEKRPPTVQEKIIMEEVVKL 1490
Cdd:pfam02463  621 rAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLE 700
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1491 EKDPDLEKSTEALRWDLDQEKTQVTELNRECKNLQVQIDVLQKAKSQEKTIYKEvIRVQKDRVLEDERARVWEMLNRERT 1570
Cdd:pfam02463  701 IKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEK-SRLKKEEKEEEKSELSLKEKELAEE 779
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1571 ARQAREEEARRLRERIDRAETLGRTWSREESELQRARDQADQECGRLQQELRALERQKQQQTLQLQEESKLLSQKtESER 1650
Cdd:pfam02463  780 REKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEE-ELER 858
                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1651 QKAAQRGQELSRLEAAILREKDQIYEKERTLrDLHAKVSREELSQETQTRETNLSTKISI 1710
Cdd:pfam02463  859 LEEEITKEELLQELLLKEEELEEQKLKDELE-SKEEKEKEEKKELEEESQKLNLLEEKEN 917
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
1348-1701 3.96e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 65.34  E-value: 3.96e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1348 LEKEAERLRQEvREAAQKRRAAEDAVYELQSKRLLLERRKpeekvvvqevvvtqkdpkLREEHSRLSGSLDEEVGRRRQL 1427
Cdd:COG1196    198 LERQLEPLERQ-AEKAERYRELKEELKELEAELLLLKLRE------------------LEAELEELEAELEELEAELEEL 258
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1428 ELEVQQLRAGVEEQegllsfqedRSKKLAVERELRQLTLRIQELEKRPPTVQEKIIMEEvvklEKDPDLEKSTEALRWDL 1507
Cdd:COG1196    259 EAELAELEAELEEL---------RLELEELELELEEAQAEEYELLAELARLEQDIARLE----ERRRELEERLEELEEEL 325
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1508 DQEKTQVTELNRECKNLQVQIDVLQKAKSQEKtiykEVIRVQKDRVLEDERARvwemLNRERTARQAREEEARRLRERID 1587
Cdd:COG1196    326 AELEEELEELEEELEELEEELEEAEEELEEAE----AELAEAEEALLEAEAEL----AEAEEELEELAEELLEALRAAAE 397
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1588 RAEtlgrtwsrEESELQRARDQADQECGRLQQELRALERQKQQQTLQLQEESKLLSQKTESERQKAAQRGQELSRLEAAI 1667
Cdd:COG1196    398 LAA--------QLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELL 469
                          330       340       350
                   ....*....|....*....|....*....|....
gi 1002819366 1668 LREKDQIYEKERTLRDLHAKVSREELSQETQTRE 1701
Cdd:COG1196    470 EEAALLEAALAELLEELAEAAARLLLLLEAEADY 503
Plectin pfam00681
Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous ...
1880-1918 5.73e-10

Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous pemphigoid antigen.


Pssm-ID: 459901  Cd Length: 39  Bit Score: 56.18  E-value: 5.73e-10
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 1002819366 1880 LLEAQAATGGIVDLLSRERYSVHKAMERGLIENTSTQRL 1918
Cdd:pfam00681    1 LLEAQAATGGIIDPVTGERLSVEEAVKRGLIDPETAQKL 39
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
804-1361 8.41e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.19  E-value: 8.41e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  804 QIAYKLQAQKRLTQEIQSRERDRATASHLSQALQAALQDYELQADTYRCSLEPTLAVSAPKRPRVAPLQESIQAQEKNLA 883
Cdd:COG1196    240 ELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLE 319
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  884 KAYTEVAAAQQQLLQQLEfarKMLEKKELSEDIRRTHDAKQGSESpAQAGRESEALKAQLEEERKRVARVQHELEAQRSQ 963
Cdd:COG1196    320 ELEEELAELEEELEELEE---ELEELEEELEEAEEELEEAEAELA-EAEEALLEAEAELAEAEEELEELAEELLEALRAA 395
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  964 LLQLRTQRPLERLEEKEVVEFYRDPQLEGSLSRVKAQVEEEGKRRAGLQADLEVAAQKVVQLESKRKTMQPHLLTKEVTQ 1043
Cdd:COG1196    396 AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALL 475
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1044 VERDPGLDSQAAQLRIQIQQLRGEDAVISARLEGLKKELLALEKREVDVKEKVVVKEVVKVEKNLEMVKAAQALRLQMEE 1123
Cdd:COG1196    476 EAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVED 555
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1124 DAARRKQAEEAVAKLQARIEDLERAissvepkviVKEVKKVEQDPGLLQESSRLRSLLEEERTKNATLARELSDLHSKYS 1203
Cdd:COG1196    556 DEVAAAAIEYLKAAKAGRATFLPLD---------KIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRT 626
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1204 VVEKQRPKVQLQERVHEIFQVDPETEQEITRLKAKLQEMAGKRSGVEKEVEKLLPDLEVLRAQKptvEYKEVTQEVVRHE 1283
Cdd:COG1196    627 LVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAE---EELELEEALLAEE 703
                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1002819366 1284 rspEVLREIDRLKAQLNELVNSHGRSQEQLIRLQGERDEWRRERAKVETKTVSKEVVRHEKDPVLEKEAERLRQEVRE 1361
Cdd:COG1196    704 ---EEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1060-1567 6.44e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 61.23  E-value: 6.44e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1060 QIQQLRGEDAVISARLEGLKKELLALEKREVDVKekvvvkevvkveknlEMVKAAQALRLQMEEDAARRKQAEEAVAKLQ 1139
Cdd:PRK03918   208 EINEISSELPELREELEKLEKEVKELEELKEEIE---------------ELEKELESLEGSKRKLEEKIRELEERIEELK 272
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1140 ARIEDLE---RAISSVEPKVIVKEVKKVEQDPgLLQESSRLRSLLEEERTKNATLARELSDLHSKYSVVEKQRPKVQLQE 1216
Cdd:PRK03918   273 KEIEELEekvKELKELKEKAEEYIKLSEFYEE-YLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELE 351
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1217 RVHEIFQVDPETEQEITRLKAKLQEMAGKRSGveKEVEKLLPDLEVLRAQKPTVEykevtqevvrherspevlREIDRLK 1296
Cdd:PRK03918   352 KRLEELEERHELYEEAKAKKEELERLKKRLTG--LTPEKLEKELEELEKAKEEIE------------------EEISKIT 411
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1297 AQLNELVNSHGRSQEQLIRLQGerdewrrerAKVETKTVSKEVVRHEKDPVLEK---EAERLRQEVREAAQKRRAAEDAV 1373
Cdd:PRK03918   412 ARIGELKKEIKELKKAIEELKK---------AKGKCPVCGRELTEEHRKELLEEytaELKRIEKELKEIEEKERKLRKEL 482
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1374 YELQSKRLLLERRKPEEKVVVQEVVVTQKDPKLR--------EEHSRLSGSLDEEVGRRRQLELEVQQLRAGVEEQEGLL 1445
Cdd:PRK03918   483 RELEKVLKKESELIKLKELAEQLKELEEKLKKYNleelekkaEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELE 562
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1446 SFQEDRSKKLA-VERELR--------QLTLRIQELEKrpptvqekiIMEEVVKLEKDP----DLEKSTEALRWDLDQEKT 1512
Cdd:PRK03918   563 KKLDELEEELAeLLKELEelgfesveELEERLKELEP---------FYNEYLELKDAEkeleREEKELKKLEEELDKAFE 633
                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1002819366 1513 QVTELNRECKNLQVQIDVLQKAKSQEKTIYKEVIRVQKDRVLEDERARVWEMLNR 1567
Cdd:PRK03918   634 ELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAELEELEKR 688
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
930-1302 2.17e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 59.69  E-value: 2.17e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  930 AQAGRESEALKAQLEEERKRVARVQHELEAQRSQLLQLRTQrpLERLEEKEVvefyrdpQLEGSLSRVKAQVEEEGKRRA 1009
Cdd:TIGR02168  680 EELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKE--LEELSRQIS-------ALRKDLARLEAEVEQLEERIA 750
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1010 GLQADLEVAAQKVVQLESKRKTMQPHLLTKEVTQVErdpgLDSQAAQLRIQIQQLRGEDAVISARLEGLKKELLALEKRE 1089
Cdd:TIGR02168  751 QLSKELTELEAEIEELEERLEEAEEELAEAEAEIEE----LEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERL 826
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1090 VdvkekvvvkevvkveknlEMVKAAQALRLQMEEDAARRKQAEEAVAKLQARIEDLERAISSVEpkvivkevkkvEQDPG 1169
Cdd:TIGR02168  827 E------------------SLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELE-----------SELEA 877
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1170 LLQESSRLRSLLEEERTKNATLARELSDLHSKysVVEKQRPKVQLQERVHEIFQVDPETEQEITRLKAKLQEMAGkrsgv 1249
Cdd:TIGR02168  878 LLNERASLEEALALLRSELEELSEELRELESK--RSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYS----- 950
                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1002819366 1250 ekevekllpdlevlraqkptVEYKEVTQEVVRHERSPEVLR-EIDRLKAQLNEL 1302
Cdd:TIGR02168  951 --------------------LTLEEAEALENKIEDDEEEARrRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
581-1361 2.64e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 59.30  E-value: 2.64e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  581 LEDLEGRIHSHEGTAQRLQSLGTEKETAQKECEAFLStrpvgpaalQLPVALNSVKNKFSDVQvlcSLYGEKAKAALDLE 660
Cdd:TIGR02168  234 LEELREELEELQEELKEAEEELEELTAELQELEEKLE---------ELRLEVSELEEEIEELQ---KELYALANEISRLE 301
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  661 RQIQDADRVIRGFEATLVQeapipaepgaLQERVSELQRQRRELLEQqtcvlrlhraLKASEHACAALQNNFQEFCQDLP 740
Cdd:TIGR02168  302 QQKQILRERLANLERQLEE----------LEAQLEELESKLDELAEE----------LAELEEKLEELKEELESLEAELE 361
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  741 RQQRQVRALTDRYHAVGDQLdlrEKVVQDAALTYQQFKNCKDNLSSWLEHLPRSQVRpsdgpsqiayklqaQKRLTQEIQ 820
Cdd:TIGR02168  362 ELEAELEELESRLEELEEQL---ETLRSKVAQLELQIASLNNEIERLEARLERLEDR--------------RERLQQEIE 424
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  821 SrerdratasHLSQALQAALQDYELQADTyrcsLEPTLAVSAPKRPRVAPLQESIQAQEKNLAKAYTEVAAAQQQLLQQL 900
Cdd:TIGR02168  425 E---------LLKKLEEAELKELQAELEE----LEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARL 491
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  901 EFARKMLEKKE-LSEDIRRThdAKQGSESPAQAGRESEALKAQLEEER---------------KRVARVQHELEAQRSQL 964
Cdd:TIGR02168  492 DSLERLQENLEgFSEGVKAL--LKNQSGLSGILGVLSELISVDEGYEAaieaalggrlqavvvENLNAAKKAIAFLKQNE 569
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  965 LQLRTQRPLERLE--EKEVVEFYRDPQLEGSLSRVKAQVEEEGKRRAGLQA---------DLEVAAQKVVQLESKRK--T 1031
Cdd:TIGR02168  570 LGRVTFLPLDSIKgtEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYllggvlvvdDLDNALELAKKLRPGYRivT 649
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1032 MQPHLLTKEVTQVERDPGLDSQAAQLRIQIQQLRGEDAVISARLEGLKKELLALEKREVDVKEKVVVKEVVKVEKNLEMV 1111
Cdd:TIGR02168  650 LDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQIS 729
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1112 ---KAAQALRLQMEEDAARRKQAEEAVAKLQARIEDLERAISSVEPKVIVKEVKKVEQDPGLLQESSRLRSLLEEERTKN 1188
Cdd:TIGR02168  730 alrKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELR 809
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1189 ATLARELSDLHSKYSVVEkqrpkvQLQERVHEIFQVDPETEQEITRLKAKLQEMAGKRSGVEKEVEKLLPDLEVLRAQKP 1268
Cdd:TIGR02168  810 AELTLLNEEAANLRERLE------SLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERA 883
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1269 TVEYKEVTQEVVRHERSP---EVLREIDRLKAQLNELVNSHGRSQEQLIRLQGERDEWR---RERAKVETKTVSKEVVRH 1342
Cdd:TIGR02168  884 SLEEALALLRSELEELSEelrELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQerlSEEYSLTLEEAEALENKI 963
                          810       820
                   ....*....|....*....|
gi 1002819366 1343 EKDP-VLEKEAERLRQEVRE 1361
Cdd:TIGR02168  964 EDDEeEARRRLKRLENKIKE 983
PLEC smart00250
Plectin repeat;
1916-1953 8.42e-08

Plectin repeat;


Pssm-ID: 197605  Cd Length: 38  Bit Score: 49.79  E-value: 8.42e-08
                            10        20        30
                    ....*....|....*....|....*....|....*...
gi 1002819366  1916 QRLLNAQKAFTGIEDPVTKKRLSVGEAVQKGWMPRESV 1953
Cdd:smart00250    1 QRLLEAQSAIGGIIDPETGQKLSVEEALRRGLIDPETG 38
SPEC cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ...
228-415 9.81e-08

Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here


Pssm-ID: 238103 [Multi-domain]  Cd Length: 213  Bit Score: 54.76  E-value: 9.81e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  228 LYTHLQGCTRQLSALAEQQRRILQQDwsDLMADPAGVRREYEHFK--QHELLSQEQSVNQLEDDGERMVELRHPAVGPIQ 305
Cdd:cd00176      1 KLQQFLRDADELEAWLSEKEELLSST--DYGDDLESVEALLKKHEalEAELAAHEERVEALNELGEQLIEEGHPDAEEIQ 78
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  306 AHQEALKMEWQNFLNLCICQETQLQHVEDYRRFQEEADSVSQTLAKLNSNLDakySPAPGGPPGAPTELLQQLEAEEKRL 385
Cdd:cd00176     79 ERLEELNQRWEELRELAEERRQRLEEALDLQQFFRDADDLEQWLEEKEAALA---SEDLGKDLESVEELLKKHKELEEEL 155
                          170       180       190
                   ....*....|....*....|....*....|
gi 1002819366  386 avtERATGDLQRRSRDVAPLPQRRNPPQQP 415
Cdd:cd00176    156 ---EAHEPRLKSLNELAEELLEEGHPDADE 182
Plectin pfam00681
Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous ...
1957-1994 1.43e-07

Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous pemphigoid antigen.


Pssm-ID: 459901  Cd Length: 39  Bit Score: 49.25  E-value: 1.43e-07
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 1002819366 1957 LQVQHLTGGLIDPKRTGRIPIQQALLSGMISEELAQLL 1994
Cdd:pfam00681    2 LEAQAATGGIIDPVTGERLSVEEAVKRGLIDPETAQKL 39
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
1170-1433 1.47e-07

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 56.67  E-value: 1.47e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1170 LLQESSRLRSLLEEERTKNATLARELSDLHSKYSVV---EKQRPKVQLQERVHEIFQVdpeTEQEITRLKAKLQEMAGKR 1246
Cdd:pfam17380  308 KAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAmerERELERIRQEERKRELERI---RQEEIAMEISRMRELERLQ 384
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1247 SGVEKEVEKLLPDLEVLRAQK-------PTVEYKEVTQEVVRHERSPEVLREIDRLKAQ----LNELVNSHGRSQEQLIR 1315
Cdd:pfam17380  385 MERQQKNERVRQELEAARKVKileeerqRKIQQQKVEMEQIRAEQEEARQREVRRLEEErareMERVRLEEQERQQQVER 464
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1316 LQGERDEWRRERAKVETKTVSKEVVRHEKDPVLEKEAERLRQEVREAAQKRRAAE-------DAVYELQSKRLLLERRKP 1388
Cdd:pfam17380  465 LRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEERKRKLLEkemeerqKAIYEEERRREAEEERRK 544
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 1002819366 1389 EEKVVVQEVVVTQKDpKLREEHSRLSGSLDEEVGRRRQLELEVQQ 1433
Cdd:pfam17380  545 QQEMEERRRIQEQMR-KATEERSRLEAMEREREMMRQIVESEKAR 588
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
936-1492 2.58e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 56.23  E-value: 2.58e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  936 SEALKAQLEEERKRVARVQHELEAQRSQLLQLRTQ-----RPLERLEE-KEVVEFYR--DPQLEGSLSRVKAQVEEEGKR 1007
Cdd:PRK03918   188 TENIEELIKEKEKELEEVLREINEISSELPELREElekleKEVKELEElKEEIEELEkeLESLEGSKRKLEEKIRELEER 267
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1008 RAGLQADLEVAAQKVVQLESKRKTMQPHL----LTKEVTQVERDpgLDSQAAQLRIQIQQLRGEDAVIS---ARLEGLKK 1080
Cdd:PRK03918   268 IEELKKEIEELEEKVKELKELKEKAEEYIklseFYEEYLDELRE--IEKRLSRLEEEINGIEERIKELEekeERLEELKK 345
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1081 ELLALEKREVDVKEKVVVkevvkveknLEMVKAaqalrLQMEEDAARRKQAEEAVAKLQARIEDLERAISSVEPKVIVKE 1160
Cdd:PRK03918   346 KLKELEKRLEELEERHEL---------YEEAKA-----KKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKIT 411
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1161 VKKVeqdpGLLQESSRLRSLLEE---ERTKNATLARELSDLHSKYSVVEKQRPKVQLQERVHEIFQVDPETEQEITRLKA 1237
Cdd:PRK03918   412 ARIG----ELKKEIKELKKAIEElkkAKGKCPVCGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEK 487
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1238 KLQ---EMAGKRSGVE--KEVEKLLPDLEVLRAQKPTVEYKEVtqevvrHERSPEVLREIDRLKAQLNELVNSHGRSQEq 1312
Cdd:PRK03918   488 VLKkesELIKLKELAEqlKELEEKLKKYNLEELEKKAEEYEKL------KEKLIKLKGEIKSLKKELEKLEELKKKLAE- 560
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1313 lirLQGERDEWRRERAKVETKTvskevvrHEKDPVLEKEAERLRQEVREAAQKRRAAEDAVYELQSKrllLERRKpeekv 1392
Cdd:PRK03918   561 ---LEKKLDELEEELAELLKEL-------EELGFESVEELEERLKELEPFYNEYLELKDAEKELERE---EKELK----- 622
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1393 vvqevvvtqkdpKLREEHSRLSGSLDEEVGRRRQLELEVQQLRAGVEEQEgllsFQEDRSKKLAVERELRQLTLRIQELE 1472
Cdd:PRK03918   623 ------------KLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEE----YEELREEYLELSRELAGLRAELEELE 686
                          570       580
                   ....*....|....*....|..
gi 1002819366 1473 KRPPTVQEKI--IMEEVVKLEK 1492
Cdd:PRK03918   687 KRREEIKKTLekLKEELEEREK 708
PTZ00121 PTZ00121
MAEBL; Provisional
1109-1701 5.98e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 55.15  E-value: 5.98e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1109 EMVKAAQALRLQMEEDAARRKQAEEAVAKLQAR-IEDLERAIssvepKVIVKEVKKVEQDPGLLQESSRLRSLLEEERTK 1187
Cdd:PTZ00121  1144 EARKAEDAKRVEIARKAEDARKAEEARKAEDAKkAEAARKAE-----EVRKAEELRKAEDARKAEAARKAEEERKAEEAR 1218
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1188 NATLARELSDLHSkysvVEKQRPKVQLQERVHEIFQVDPETEQEITRLKAKLQEMAGKRSGVEKEVEKLLPDLEVLRAQK 1267
Cdd:PTZ00121  1219 KAEDAKKAEAVKK----AEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADE 1294
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1268 PtveykevtqevvrheRSPEVLREIDRLKAQLNElvnshGRSQEQLiRLQGERDEWRRERAKVETKTVSKevvrheKDPV 1347
Cdd:PTZ00121  1295 A---------------KKAEEKKKADEAKKKAEE-----AKKADEA-KKKAEEAKKKADAAKKKAEEAKK------AAEA 1347
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1348 LEKEAERLRQEVREAAQKRRAAEDAVYELQSKRLLLERRKPEEKVVVQEVVVTQKDPKLREEhsrlsgsldeeVGRRRQL 1427
Cdd:PTZ00121  1348 AKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADE-----------LKKAAAA 1416
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1428 ELEVQQLRAGVEEQEgllsfQEDRSKKLAVERElrqltlRIQELEKRpptVQEKIIMEEVVKleKDPDLEKSTEALRwdL 1507
Cdd:PTZ00121  1417 KKKADEAKKKAEEKK-----KADEAKKKAEEAK------KADEAKKK---AEEAKKAEEAKK--KAEEAKKADEAKK--K 1478
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1508 DQEKTQVTELNRECKNLQVQIDVLQKaKSQEKTIYKEVIRVQKDRVLEDERARvwemlNRERTARQAREEEARRLRERID 1587
Cdd:PTZ00121  1479 AEEAKKADEAKKKAEEAKKKADEAKK-AAEAKKKADEAKKAEEAKKADEAKKA-----EEAKKADEAKKAEEKKKADELK 1552
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1588 RAETLGRTWSREESELQRARDQADQECGRLQQELRALERQKQQQTLQLQEESKLL----SQKTESERQKAAQ-------- 1655
Cdd:PTZ00121  1553 KAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMkaeeAKKAEEAKIKAEElkkaeeek 1632
                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*..
gi 1002819366 1656 -RGQELSRLEAAILREKDQIYEKERTLRDLHAKVSREELSQETQTRE 1701
Cdd:PTZ00121  1633 kKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEE 1679
PLEC smart00250
Plectin repeat;
1878-1911 6.52e-07

Plectin repeat;


Pssm-ID: 197605  Cd Length: 38  Bit Score: 47.48  E-value: 6.52e-07
                            10        20        30
                    ....*....|....*....|....*....|....
gi 1002819366  1878 QKLLEAQAATGGIVDLLSRERYSVHKAMERGLIE 1911
Cdd:smart00250    1 QRLLEAQSAIGGIIDPETGQKLSVEEALRRGLID 34
PTZ00121 PTZ00121
MAEBL; Provisional
872-1424 1.02e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 54.38  E-value: 1.02e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  872 QESIQAQEKNLAKAYTEVAAAQQQLLQQLEFARKMLEKKElSEDIRRTHDAKQGSES-PAQAGRESEALKAQLEEERK-R 949
Cdd:PTZ00121  1240 EEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARK-ADELKKAEEKKKADEAkKAEEKKKADEAKKKAEEAKKaD 1318
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  950 VARVQHELEAQRSQLLQLRTQRPLERLEEKEVVEFYRDPQLEGSLSRVKA--QVEEEGKRRAglqADLEVAAQKVVQLES 1027
Cdd:PTZ00121  1319 EAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAaeKKKEEAKKKA---DAAKKKAEEKKKADE 1395
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1028 KRKTMQPHllTKEVTQVERDPGLDSQAAQLRIQIQQLRGED-----AVISARLEGLKKELLALEKREVDVKEKVVVKEVV 1102
Cdd:PTZ00121  1396 AKKKAEED--KKKADELKKAAAAKKKADEAKKKAEEKKKADeakkkAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKAD 1473
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1103 KVEKNLEMVKAAQALRLQMEEdaaRRKQAEEAVAKLQA--RIEDLERAISSVEPKVIVKEVKKVEQDpgllqessRLRSL 1180
Cdd:PTZ00121  1474 EAKKKAEEAKKADEAKKKAEE---AKKKADEAKKAAEAkkKADEAKKAEEAKKADEAKKAEEAKKAD--------EAKKA 1542
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1181 LEEERTKNATLARELSDLHSKYSVVEKQRP---KVQLQERVHEIFQVDPETEQEITRLKAKLQEMAGKRSGVEKEVEKLL 1257
Cdd:PTZ00121  1543 EEKKKADELKKAEELKKAEEKKKAEEAKKAeedKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKA 1622
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1258 PDLEVLRAQKPTVEY--KEVTQEVVRHERSPEVLREIDRLKAQLNELVNSHGRSQEQLIRlqGERDEWRRERA---KVET 1332
Cdd:PTZ00121  1623 EELKKAEEEKKKVEQlkKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKK--AEEDEKKAAEAlkkEAEE 1700
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1333 KTVSKEVVRHEKDPVleKEAERLRQEvrEAAQKRRAAEDAVYELQSKRLLLERRKPEEKVVVQEVVVTQKDPKLREEHSR 1412
Cdd:PTZ00121  1701 AKKAEELKKKEAEEK--KKAEELKKA--EEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKE 1776
                          570
                   ....*....|..
gi 1002819366 1413 LSGSLDEEVGRR 1424
Cdd:PTZ00121  1777 KEAVIEEELDEE 1788
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1213-1688 1.44e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 53.53  E-value: 1.44e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1213 QLQERVHEIFQVDPETEQEITRLKAKLQEMAGKRSGVEKEV---EKLLPDLEVLRAQKPTVEYKEVTQEvvrhERSPEVL 1289
Cdd:PRK03918   190 NIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVkelEELKEEIEELEKELESLEGSKRKLE----EKIRELE 265
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1290 REIDRLKAQLNELVNSHGRSQE------QLIRLQGERDEWRRERAKVEtKTVSKEVVRHEKDPVLEKEAERLRQEVREAA 1363
Cdd:PRK03918   266 ERIEELKKEIEELEEKVKELKElkekaeEYIKLSEFYEEYLDELREIE-KRLSRLEEEINGIEERIKELEEKEERLEELK 344
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1364 QKRRAAEDAVYELQSKRLLLERRKPEEKVVVQEVVVTQKDP---------KLREEHSRLSGSLDEEVGRRRQLELEVQQL 1434
Cdd:PRK03918   345 KKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTpeklekeleELEKAKEEIEEEISKITARIGELKKEIKEL 424
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1435 RAGVEEQE---------GLLSFQEDRSKKLA--------VERELRQLTLRIQELEKRPPTVQEKIIME-EVVKLEKDPD- 1495
Cdd:PRK03918   425 KKAIEELKkakgkcpvcGRELTEEHRKELLEeytaelkrIEKELKEIEEKERKLRKELRELEKVLKKEsELIKLKELAEq 504
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1496 ---LEKSTEALRW-DLDQEKTQVTELNRECKNLQVQIDVLQKAKSQEKTIYKEVIRVQKD-RVLEDERARVwemlnrERT 1570
Cdd:PRK03918   505 lkeLEEKLKKYNLeELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKlDELEEELAEL------LKE 578
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1571 ARQAREEEARRLRERIDRAETLGRTWSR---EESELQRARDQADQECGRLQQELRALERQKQQQTLQLQEESKLLSQKTE 1647
Cdd:PRK03918   579 LEELGFESVEELEERLKELEPFYNEYLElkdAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSE 658
                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*
gi 1002819366 1648 SERQKAAQR----GQELSRLEAAILREKDQIYEKERTLRDLHAKV 1688
Cdd:PRK03918   659 EEYEELREEylelSRELAGLRAELEELEKRREEIKKTLEKLKEEL 703
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
1175-1702 1.56e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 53.58  E-value: 1.56e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1175 SRLRSLLEEERTKNATLARELSDLHSKYSVV--EKQRPKVQLQERVHEIFQVDPETEQEITRLKAKLQEMAGKRSGVEKE 1252
Cdd:pfam15921  299 SQLEIIQEQARNQNSMYMRQLSDLESTVSQLrsELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQ 378
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1253 VEKLLPDLEvlRAQKPTVEYKEVTQEVVRHERSPEVlrEIDRLKAQLNELVNSHGRSQEQLIRLQGE-RDEWRRERAKVE 1331
Cdd:pfam15921  379 LQKLLADLH--KREKELSLEKEQNKRLWDRDTGNSI--TIDHLRRELDDRNMEVQRLEALLKAMKSEcQGQMERQMAAIQ 454
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1332 TKTVSKEVVRhEKDPVLEKEAERLRQevreaaqkrraaedAVYELQSKRLLLERRKpeekvvvqeVVVTQKDPKLREEHS 1411
Cdd:pfam15921  455 GKNESLEKVS-SLTAQLESTKEMLRK--------------VVEELTAKKMTLESSE---------RTVSDLTASLQEKER 510
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1412 RLSGSLDEEVGRRRQLELEVQQLRAGVEEQEGLLSFQ-EDRSKKLAVERELRQLTLRIQELEKRPPTVQEKIIMEEVVKL 1490
Cdd:pfam15921  511 AIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQtECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQV 590
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1491 EKdPDLEKSTEALRWDLDQEKTQVTELNRECKNLQVQIDVLQKAKSQEKTIYKEVIRVQKDrvLEDERArvwEMLNRERT 1570
Cdd:pfam15921  591 EK-AQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKD--IKQERD---QLLNEVKT 664
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1571 ARQAREEEArrlreriDRAETLGRTWSREESELQRARDQADQECGRLQQElraLERQKQQQTLQLQEESKLLSQKTESER 1650
Cdd:pfam15921  665 SRNELNSLS-------EDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSE---LEQTRNTLKSMEGSDGHAMKVAMGMQK 734
                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1002819366 1651 QKAAQRGQelsrLEAaiLREKDQIYEKERTLRDLHAKVSREE---LSQETQTRET 1702
Cdd:pfam15921  735 QITAKRGQ----IDA--LQSKIQFLEEAMTNANKEKHFLKEEknkLSQELSTVAT 783
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
1212-1539 3.02e-06

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 52.43  E-value: 3.02e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1212 VQLQERVHEIFQVDPETEQEITRLKAKLQEMAgkrsgveKEVEKLLPDLEVLRAQKPTVEyKEVTQEVVRHERSPEVLRE 1291
Cdd:pfam17380  278 VQHQKAVSERQQQEKFEKMEQERLRQEKEEKA-------REVERRRKLEEAEKARQAEMD-RQAAIYAEQERMAMERERE 349
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1292 IDRLKAQLNELVNSHGRSQE---------QLIRLQGERDEwRRERakvetktVSKEVVRHEKDPVLEKEAERLRQEVREA 1362
Cdd:pfam17380  350 LERIRQEERKRELERIRQEEiameisrmrELERLQMERQQ-KNER-------VRQELEAARKVKILEEERQRKIQQQKVE 421
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1363 AQKRRAAEDAVYELQSKRLLLERRKPEEKVVVQEVVVTQKDPKLREehsrlsgslDEEVGRRRQLELEVQQL-RAGVEEQ 1441
Cdd:pfam17380  422 MEQIRAEQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQ---------QEEERKRKKLELEKEKRdRKRAEEQ 492
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1442 EGLLSFQEDRSKKLAVERELRQLTLRIQELEKRPPTVQEKiimEEVVKLEKDPDLEKSTEAlRWDLDQEKTQVTELNREC 1521
Cdd:pfam17380  493 RRKILEKELEERKQAMIEEERKRKLLEKEMEERQKAIYEE---ERRREAEEERRKQQEMEE-RRRIQEQMRKATEERSRL 568
                          330
                   ....*....|....*...
gi 1002819366 1522 KNLQVQIDVLQKAKSQEK 1539
Cdd:pfam17380  569 EAMEREREMMRQIVESEK 586
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
651-1473 3.55e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 52.38  E-value: 3.55e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  651 EKAKAALDLERQIQDADRVIRGFEATLVQeapIPAEPGALQERVSELQRQRRELLEqqtcvlrlhRALKASEHACAALQN 730
Cdd:TIGR02169  227 ELLKEKEALERQKEAIERQLASLEEELEK---LTEEISELEKRLEEIEQLLEELNK---------KIKDLGEEEQLRVKE 294
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  731 NFQEFCQDLPRQQRQVRALTDRyhavgdqldlrekvVQDAALTYQQFKNCKDNLSSWLEHLPRS----QVRPSDGPSQIA 806
Cdd:TIGR02169  295 KIGELEAEIASLERSIAEKERE--------------LEDAEERLAKLEAEIDKLLAEIEELEREieeeRKRRDKLTEEYA 360
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  807 YKLQAQKRLTQEIQSRERDRATASHLSQALQAALQDYELQADTYRCSLEPTLAVSAPKRPRVAPLQESIQAQEKNLAKAY 886
Cdd:TIGR02169  361 ELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELE 440
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  887 TEVaaaqqqllqqlEFARKMLEKKElsedirrtHDAKQGSESPAQAGRESEALKA---QLEEERKRVARVQHELEAQRSQ 963
Cdd:TIGR02169  441 EEK-----------EDKALEIKKQE--------WKLEQLAADLSKYEQELYDLKEeydRVEKELSKLQRELAEAEAQARA 501
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  964 LLQlrtqrplERLEEKEVVEFyrdpqLEGSLSRVKAQVEEEGKRRAGLQADLEVA---------------AQKVVQLESK 1028
Cdd:TIGR02169  502 SEE-------RVRGGRAVEEV-----LKASIQGVHGTVAQLGSVGERYATAIEVAagnrlnnvvveddavAKEAIELLKR 569
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1029 RK----TMQPhlLTKeVTQVERDPGLDSQAAQLRIQIQQLRGED----AVISARLEGLKKELLALEKREVDVKEKVVVKE 1100
Cdd:TIGR02169  570 RKagraTFLP--LNK-MRDERRDLSILSEDGVIGFAVDLVEFDPkyepAFKYVFGDTLVVEDIEAARRLMGKYRMVTLEG 646
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1101 VVKVEKNLeMVKAAQALRlqmeEDAARRKQAEEAVAKLQARIEDLERAISSvepkvivkevkkveqdpgLLQESSRLRSL 1180
Cdd:TIGR02169  647 ELFEKSGA-MTGGSRAPR----GGILFSRSEPAELQRLRERLEGLKRELSS------------------LQSELRRIENR 703
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1181 LEEERTKNATLARELSDLHSKYSVVEKQRPKV-----QLQERVHEIFQVDPETEQEITRLKAKLQEMAGKRSGVEKEVEK 1255
Cdd:TIGR02169  704 LDELSQELSDASRKIGEIEKEIEQLEQEEEKLkerleELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALND 783
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1256 LLPDLEVLRAQKPTVEYKEVTQEVVRHErspEVLREIDR-------LKAQLNELVNShgrSQEQLIRLQGERDEWRRERA 1328
Cdd:TIGR02169  784 LEARLSHSRIPEIQAELSKLEEEVSRIE---ARLREIEQklnrltlEKEYLEKEIQE---LQEQRIDLKEQIKSIEKEIE 857
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1329 -----KVETKTVSKEVVRHEKDpvLEKEAERLRQEVREAAQKRRAAEDAVYELQS----KRLLLERRKPEEKVVVQEVVV 1399
Cdd:TIGR02169  858 nlngkKEELEEELEELEAALRD--LESRLGDLKKERDELEAQLRELERKIEELEAqiekKRKRLSELKAKLEALEEELSE 935
                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1002819366 1400 TQKDPKLREEHSRLSGSLDEEVGRRRQLELEVQQL-----RAGVEEQEGLLSFQEDRSKKLAVERELRQLTLRIQELEK 1473
Cdd:TIGR02169  936 IEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALepvnmLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEK 1014
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
688-1317 3.87e-06

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 52.28  E-value: 3.87e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  688 GALQERVSELQRQRRELLEQQTCVLRLHRALKASEHACAALQNNFQEFcQDLPRQQRQVRALTDRYHAVGDQLDLREKVV 767
Cdd:TIGR00618  263 KQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQ-RIHTELQSKMRSRAKLLMKRAAHVKQQSSIE 341
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  768 QDAALTYQQFKNCKDNlsswlehlprsqVRPSDGPSQIAYKLQAQKRLTQEIQSRERDRATASHLSQALQAALqdyeLQA 847
Cdd:TIGR00618  342 EQRRLLQTLHSQEIHI------------RDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKEL----DIL 405
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  848 DTYRCSLEPTLAVSAPKRPRVAPLQESIQAQEKNLAKAYTEVAAAQQQLLQQLEFARKMLEKkeLSEDIRRTHDAKQGSE 927
Cdd:TIGR00618  406 QREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQS--LKEREQQLQTKEQIHL 483
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  928 SPAQAGRESEALKAQLEEERKRVARVQHELEAQRSQLLQLR-TQRPLERLEekevvefYRDPQLEGSLSRVKAQVEEEGK 1006
Cdd:TIGR00618  484 QETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGpLTRRMQRGE-------QTYAQLETSEEDVYHQLTSERK 556
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1007 RRAGLQADLEVAAQKVVQLESKRKTMQPHLltkEVTQVERDPGLDSQAAQLRIQIQQLRGEDAVISARLEGLKKELLALE 1086
Cdd:TIGR00618  557 QRASLKEQMQEIQQSFSILTQCDNRSKEDI---PNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLH 633
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1087 KREVDVKEKVVVKEVVKVEKNLEMVKAAQALRLQMEEDAARRKQAEEAVAKLQARIEDLERAISSVEPKVIVKEVKKVEq 1166
Cdd:TIGR00618  634 LQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETH- 712
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1167 dpglLQESSRLRSLLEE-ERTKNATLARELSDLHSKYSVVEKQRPKvQLQERVHEIFQVDPETEQEITRLkAKLQEMAGK 1245
Cdd:TIGR00618  713 ----IEEYDREFNEIENaSSSLGSDLAAREDALNQSLKELMHQART-VLKARTEAHFNNNEEVTAALQTG-AELSHLAAE 786
                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1002819366 1246 RSGVEKEVEKLLPDLEVLRAQ-----KPTVEYKEVTQEVVRHERSpEVLREIDRLKAQLNELVNSHGRSQEQLIRLQ 1317
Cdd:TIGR00618  787 IQFFNRLREEDTHLLKTLEAEigqeiPSDEDILNLQCETLVQEEE-QFLSRLEEKSATLGEITHQLLKYEECSKQLA 862
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
1131-1711 4.01e-06

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 52.28  E-value: 4.01e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1131 AEEAVAKLQARIEDLERAISSVEPKVIVKEVKKV--EQDPGLLQESSRLRSLLEEERTKNATLARELSDLHSKYSVVEKQ 1208
Cdd:TIGR00618  210 TPCMPDTYHERKQVLEKELKHLREALQQTQQSHAylTQKREAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERINRA 289
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1209 RPKVQLQERVHEIFQVDPETEQEITRLKAKLQEMAGKRSGV------EKEVEKLLPDLEVLRAQKPTVEyKEVTQEVVRH 1282
Cdd:TIGR00618  290 RKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRaahvkqQSSIEEQRRLLQTLHSQEIHIR-DAHEVATSIR 368
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1283 ERSPEVLREIDRLKAQ------LNELVNSHGRSQEQLIRLQG-------ERDEWRRERAKVETKTVSKEVVRHEKDPVLE 1349
Cdd:TIGR00618  369 EISCQQHTLTQHIHTLqqqkttLTQKLQSLCKELDILQREQAtidtrtsAFRDLQGQLAHAKKQQELQQRYAELCAAAIT 448
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1350 KEAERLRQEVREAAQKRRAAEDAVYELQSKRLLLERRKPEEKVVVQEVVVTQKDPKLREE-------HSRLSGSLDEEVG 1422
Cdd:TIGR00618  449 CTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGscihpnpARQDIDNPGPLTR 528
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1423 RRRQLELEVQQLRAGVEEQEGLLSFQEDRSKKLAverelRQLTLRIQELEKRPPTVQE-KIIMEEVVKLEKD--PDLEKS 1499
Cdd:TIGR00618  529 RMQRGEQTYAQLETSEEDVYHQLTSERKQRASLK-----EQMQEIQQSFSILTQCDNRsKEDIPNLQNITVRlqDLTEKL 603
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1500 TEALRWDLDQEKTQVTELNRECKNLQVQIDVLQKAKSQEK----------TIYKEVIRVQKDRVLEDErARVWEMLNRER 1569
Cdd:TIGR00618  604 SEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALkltalhalqlTLTQERVREHALSIRVLP-KELLASRQLAL 682
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1570 TARQAREEEARRLRERIDRAETLGRTWSREESELQRARDQADQECGRLQQELRALERQKQQQTLQLQEESKLLSQKTESE 1649
Cdd:TIGR00618  683 QKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEA 762
                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1002819366 1650 RQKAA-------QRGQELSRLEAAILREKDQIYEKERTLRDLHAKVSRE--------ELSQET-QTRETNLSTKISIL 1711
Cdd:TIGR00618  763 HFNNNeevtaalQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEipsdedilNLQCETlVQEEEQFLSRLEEK 840
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
901-1444 6.78e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 51.22  E-value: 6.78e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  901 EFARKMLEKKELSEDIRRTHDAKQGSESPAQagrESEALKAQLEEERKRVARVQHELEAQRSQLLQLRTQRP-----LER 975
Cdd:PRK03918   201 ELEEVLREINEISSELPELREELEKLEKEVK---ELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEelkkeIEE 277
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  976 LEEK---------------EVVEFYRdpQLEGSLSRVKAQVEEEGKRRAGLQADLEVAAQKVVQLESKRKTMQPhlLTKE 1040
Cdd:PRK03918   278 LEEKvkelkelkekaeeyiKLSEFYE--EYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKE--LEKR 353
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1041 VTQVERDPGLDSQAAQLRIQIQQLRGEDAVISarLEGLKKELLALEKREVDVKEKVVVKEVVKVeknlEMVKAAQALRLQ 1120
Cdd:PRK03918   354 LEELEERHELYEEAKAKKEELERLKKRLTGLT--PEKLEKELEELEKAKEEIEEEISKITARIG----ELKKEIKELKKA 427
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1121 MEE-DAARRK-----------QAEEAVAKLQARIEDLERAISSVEPKVIVkevkkveqdpgLLQESSRLRSLLEEERT-- 1186
Cdd:PRK03918   428 IEElKKAKGKcpvcgrelteeHRKELLEEYTAELKRIEKELKEIEEKERK-----------LRKELRELEKVLKKESEli 496
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1187 KNATLARELSDLHSKYSVVEKQRPKvqlqervheifqvdpETEQEITRLKAKLQEMAGKRSGVEKEVEKllpdLEVLRAQ 1266
Cdd:PRK03918   497 KLKELAEQLKELEEKLKKYNLEELE---------------KKAEEYEKLKEKLIKLKGEIKSLKKELEK----LEELKKK 557
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1267 KPTVEYKEVTQEvvrhERSPEVLREIDRLKAQLNELVNSHGRSQEQL----IRLQGERDEWRRERAKVEtKTVSKEVVRH 1342
Cdd:PRK03918   558 LAELEKKLDELE----EELAELLKELEELGFESVEELEERLKELEPFyneyLELKDAEKELEREEKELK-KLEEELDKAF 632
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1343 EKDPVLEKEAERLRQEVREAaqKRRAAEDAVYELQSKRLLLERRKPEEKVVVQEVVvtqkdpKLREEHSRLSGSLDEEVG 1422
Cdd:PRK03918   633 EELAETEKRLEELRKELEEL--EKKYSEEEYEELREEYLELSRELAGLRAELEELE------KRREEIKKTLEKLKEELE 704
                          570       580
                   ....*....|....*....|..
gi 1002819366 1423 RRRQLELEVQQLRAGVEEQEGL 1444
Cdd:PRK03918   705 EREKAKKELEKLEKALERVEEL 726
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
651-1154 8.82e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 51.09  E-value: 8.82e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  651 EKAKAALDLERQIQDADRVIRGFEATLVQEApipAEPGALQERVSELQRQRRELLEQqtcVLRLHRALKASEHACAALQN 730
Cdd:COG1196    243 ELEAELEELEAELEELEAELAELEAELEELR---LELEELELELEEAQAEEYELLAE---LARLEQDIARLEERRRELEE 316
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  731 NFQEFCQDLPRQQRQVRALTDRYHAVGDQLDLREKVVQDAALTYQQFKN-----------CKDNLSSWLEHLPRSQVRPS 799
Cdd:COG1196    317 RLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEalleaeaelaeAEEELEELAEELLEALRAAA 396
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  800 DGPSQIAYKLQAQKRLTQEIQSRERDRATASHLSQALQAALQDYELQADTYRCSLEPTLAVSAPKRPRVAPLQESIQAQE 879
Cdd:COG1196    397 ELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLE 476
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  880 KNLAKAYTEVAAAQQQLLQQLEFARKM---------LEKKELSEDIRRTHDAKQGSESPAQAGRESEALKAQLEEERKRV 950
Cdd:COG1196    477 AALAELLEELAEAAARLLLLLEAEADYegflegvkaALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDD 556
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  951 ARVQHELEAQRSQLLQLRTQRPLERLEEKEVVEFYRDPQLEGSLSR-VKAQVEEEGKRRAGLQADLEVAAQKVVQLESKR 1029
Cdd:COG1196    557 EVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDlVASDLREADARYYVLGDTLLGRTLVAARLEAAL 636
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1030 KTMQPHLLTKEVTQVERDPGLDSQA-----------AQLRIQIQQLRGEDAVISARLEGLKKELLALEKREVDVKEKVVV 1098
Cdd:COG1196    637 RRAVTLAGRLREVTLEGEGGSAGGSltggsrrellaALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEER 716
                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1002819366 1099 KEVVKVEKNLEMVKAAQALRLQME---------EDAARRKQAEEAVAKLQARIEDLERAISSVEP 1154
Cdd:COG1196    717 LEEELEEEALEEQLEAEREELLEElleeeelleEEALEELPEPPDLEELERELERLEREIEALGP 781
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1175-1387 2.59e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.53  E-value: 2.59e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1175 SRLRSLLEEERTKNATL------ARELSDLHSKYSVVEKQRPKVQLQERVHEIFQVdpetEQEITRLKAKLQEMAGKRSG 1248
Cdd:COG4913    238 ERAHEALEDAREQIELLepirelAERYAAARERLAELEYLRAALRLWFAQRRLELL----EAELEELRAELARLEAELER 313
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1249 VEKEVEKLLPDLEVLRAQKPTVEYKEVTQevvrherspeVLREIDRLKAQLNELVNSHGRSQEQLIRLQ----GERDEWR 1324
Cdd:COG4913    314 LEARLDALREELDELEAQIRGNGGDRLEQ----------LEREIERLERELEERERRRARLEALLAALGlplpASAEEFA 383
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1002819366 1325 RERAKVetktvskevvrHEKDPVLEKEAERLRQEVREAAQKRRAAEDAVYELQSKRLLLERRK 1387
Cdd:COG4913    384 ALRAEA-----------AALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRK 435
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
700-1082 3.19e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 49.18  E-value: 3.19e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  700 QRRELLEQqtcVLRLHRALKASEHACAALQNNFQEFCQDLPRQQRQVRALTDRYHAVGDQLDLrekvVQDAALTYQQFKN 779
Cdd:COG3096    279 ERRELSER---ALELRRELFGARRQLAEEQYRLVEMARELEELSARESDLEQDYQAASDHLNL----VQTALRQQEKIER 351
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  780 CKDNLSSwlehlprsqvrpsdgpsqIAYKLQAQKRLTQEIQSRERDRATASHLSQA----LQAALQDYE----------- 844
Cdd:COG3096    352 YQEDLEE------------------LTERLEEQEEVVEEAAEQLAEAEARLEAAEEevdsLKSQLADYQqaldvqqtrai 413
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  845 -----LQA--DTYRCSLEPTLAVSApkrprVAPLQESIQAQEKNLakayTEVAAAQQQLLQQLEFARKMLEKK-ELSEDI 916
Cdd:COG3096    414 qyqqaVQAleKARALCGLPDLTPEN-----AEDYLAAFRAKEQQA----TEEVLELEQKLSVADAARRQFEKAyELVCKI 484
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  917 ------RRTHDA-----KQGSESPAQAGREsEALKAQLEEERKRVARvQHELEAQRSQLLQlRTQRPLERLEEKEVVEfy 985
Cdd:COG3096    485 ageverSQAWQTarellRRYRSQQALAQRL-QQLRAQLAELEQRLRQ-QQNAERLLEEFCQ-RIGQQLDAAEELEELL-- 559
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  986 rdPQLEGSLSRVKAQVEEEGKRRAGLQADLEVAAQKVVQLESK----------------------------RKTMQpHLL 1037
Cdd:COG3096    560 --AELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAARapawlaaqdalerlreqsgealadsqevTAAMQ-QLL 636
                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*.
gi 1002819366 1038 TKEV-TQVERDPgLDSQAAQLRIQIQQLRGEDAVISARLEGLKKEL 1082
Cdd:COG3096    637 EREReATVERDE-LAARKQALESQIERLSQPGGAEDPRLLALAERL 681
SPEC cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ...
156-330 7.08e-05

Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here


Pssm-ID: 238103 [Multi-domain]  Cd Length: 213  Bit Score: 46.28  E-value: 7.08e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  156 LEQKQKQVCAGQYGPGMAELEQQIAEHNILQKEIDAY----------GQQLRSLVGPDAATIR-------SQYRDLLKAA 218
Cdd:cd00176     16 LSEKEELLSSTDYGDDLESVEALLKKHEALEAELAAHeervealnelGEQLIEEGHPDAEEIQerleelnQRWEELRELA 95
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  219 SWRGQSLG---SLYTHLQGCTRQLSALAEQQRRILQQDWSDlmaDPAGVRREYEHFK--QHELLSQEQSVNQLEDDGERM 293
Cdd:cd00176     96 EERRQRLEealDLQQFFRDADDLEQWLEEKEAALASEDLGK---DLESVEELLKKHKelEEELEAHEPRLKSLNELAEEL 172
                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 1002819366  294 VELRHPAVGP-IQAHQEALKMEWQNFLNLCICQETQLQ 330
Cdd:cd00176    173 LEEGHPDADEeIEEKLEELNERWEELLELAEERQKKLE 210
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1055-1552 7.82e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 47.75  E-value: 7.82e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1055 AQLRIQIQQLRGEDAVISARLEGLKKELLALEKREVDVKEKVVVKEVVKveknlEMVKAAQALRLQMEEDAARRKQAEEA 1134
Cdd:PRK03918   241 EELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELK-----EKAEEYIKLSEFYEEYLDELREIEKR 315
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1135 VAKLQARIEDLERAISSVEPKVIVKEVKKVEQDpGLLQESSRLrslleEERTKNATLARELSDLHSKYSVVEKQRPKVQL 1214
Cdd:PRK03918   316 LSRLEEEINGIEERIKELEEKEERLEELKKKLK-ELEKRLEEL-----EERHELYEEAKAKKEELERLKKRLTGLTPEKL 389
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1215 QERVHEIFQVDPETEQEITRLKAKLQEMAGKRSGVEKEVEKllpdLEVLRAQKPTVEyKEVTQEvVRHERSPEVLREIDR 1294
Cdd:PRK03918   390 EKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEE----LKKAKGKCPVCG-RELTEE-HRKELLEEYTAELKR 463
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1295 LKAQLNELVNSHGRSQEQLIRLQGERDEWRRERAKVETKTVSKEVVRHEKDPVLEK------EAERLRQEVREAAQKRRA 1368
Cdd:PRK03918   464 IEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEElekkaeEYEKLKEKLIKLKGEIKS 543
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1369 AEDAV---YELQSKRLLLERRKPEEKVVVQEVVVtqkdpKLREEHSRLSGSLDEEVGR-----RRQLELE--VQQLRAGV 1438
Cdd:PRK03918   544 LKKELeklEELKKKLAELEKKLDELEEELAELLK-----ELEELGFESVEELEERLKElepfyNEYLELKdaEKELEREE 618
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1439 EEQEGLLSFQEDRSKKLA-VERELRQLTLRIQELEKRPPTVQEKIIMEEVVKLEKDpdleksTEALRWDLDQEKTQVTEL 1517
Cdd:PRK03918   619 KELKKLEEELDKAFEELAeTEKRLEELRKELEELEKKYSEEEYEELREEYLELSRE------LAGLRAELEELEKRREEI 692
                          490       500       510
                   ....*....|....*....|....*....|....*
gi 1002819366 1518 NRECKNLQVQIDVLQKAKSQEKTIYKEVIRVQKDR 1552
Cdd:PRK03918   693 KKTLEKLKEELEEREKAKKELEKLEKALERVEELR 727
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1286-1474 8.46e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.99  E-value: 8.46e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1286 PEVLREIDRLKAQLNELVNSHGRS---QEQLIRLQGERDEWRRERAKVETKTVSKEVV-------RHEKDPVLEKEAERL 1355
Cdd:COG4913    221 PDTFEAADALVEHFDDLERAHEALedaREQIELLEPIRELAERYAAARERLAELEYLRaalrlwfAQRRLELLEAELEEL 300
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1356 RQEVREAAQKRRAAEDAVYELQSKRLLLERRKPEEKVVVQEVVVTQKDpKLREEHSRLSGSLDEEVGRRRQLEL------ 1429
Cdd:COG4913    301 RAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIE-RLERELEERERRRARLEALLAALGLplpasa 379
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1002819366 1430 --------EVQQLRAGVEEQEGLLS--FQEDRSKKLAVERELRQLTLRIQELEKR 1474
Cdd:COG4913    380 eefaalraEAAALLEALEEELEALEeaLAEAEAALRDLRRELRELEAEIASLERR 434
SPEC smart00150
Spectrin repeats;
237-330 8.69e-05

Spectrin repeats;


Pssm-ID: 197544 [Multi-domain]  Cd Length: 101  Bit Score: 43.47  E-value: 8.69e-05
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366   237 RQLSALAEQQRRILQQDwsDLMADPAGVRREYEHFK--QHELLSQEQSVNQLEDDGERMVELRHPAVGPIQAHQEALKME 314
Cdd:smart00150    8 DELEAWLEEKEQLLASE--DLGKDLESVEALLKKHEafEAELEAHEERVEALNELGEQLIEEGHPDAEEIEERLEELNER 85
                            90
                    ....*....|....*.
gi 1002819366   315 WQNFLNLCICQETQLQ 330
Cdd:smart00150   86 WEELKELAEERRQKLE 101
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
817-1571 1.04e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 47.76  E-value: 1.04e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  817 QEIQSRERDRATASHLsQALQAALQDYEL-----QADTYRCSLEPTLAVSAPKRPRVAPLQESIQAQEKNLAKAYTEVAA 891
Cdd:TIGR02169  198 QQLERLRREREKAERY-QALLKEKREYEGyellkEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEE 276
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  892 AQQQLLQQLE-----FARKMLEKKELSEDIRRTHDAKQGSESPAQAGR------------ESEALKAQLEEERKRVARVQ 954
Cdd:TIGR02169  277 LNKKIKDLGEeeqlrVKEKIGELEAEIASLERSIAEKERELEDAEERLakleaeidkllaEIEELEREIEEERKRRDKLT 356
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  955 HELEAQRSQLLQLRTQ-------------RPLERLEEKEVVEFYRDPqLEGSLSRVKAQVEEEGKRRAGLQADLEVAAQK 1021
Cdd:TIGR02169  357 EEYAELKEELEDLRAEleevdkefaetrdELKDYREKLEKLKREINE-LKRELDRLQEELQRLSEELADLNAAIAGIEAK 435
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1022 VVQLESKRKTMQPHLLTKEvTQVERdpgLDSQAAQLRIQIQQLRGEDAVISARLEGLKKELLALEKREVDVKEKVVVKEV 1101
Cdd:TIGR02169  436 INELEEEKEDKALEIKKQE-WKLEQ---LAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRA 511
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1102 VKVEKN------------LEMVKAAQAL--------RLQM-----EEDAAR------RKQAEEA----VAKLQARIEDLE 1146
Cdd:TIGR02169  512 VEEVLKasiqgvhgtvaqLGSVGERYATaievaagnRLNNvvvedDAVAKEaiellkRRKAGRAtflpLNKMRDERRDLS 591
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1147 R---------AISSVE-PKVIVKEVKKVEQDPGLLQESSRLRSLLEEERTknATLARELSD-----------LHSKYSVV 1205
Cdd:TIGR02169  592 IlsedgvigfAVDLVEfDPKYEPAFKYVFGDTLVVEDIEAARRLMGKYRM--VTLEGELFEksgamtggsraPRGGILFS 669
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1206 EKQRPKVQ-LQERVHE-------IFQVDPETEQEITRLKAKLQEMAGKRSGVEKEVEKLLPDLEVLRAQkptVEYKEVTQ 1277
Cdd:TIGR02169  670 RSEPAELQrLRERLEGlkrelssLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKER---LEELEEDL 746
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1278 EVVRHERSpEVLREIDRLKAQLNELVNSHGRSQEQLIRLQGERDEWRRERAKVETKTVSKEVVRhekdpvLEKEAERLRQ 1357
Cdd:TIGR02169  747 SSLEQEIE-NVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSR------IEARLREIEQ 819
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1358 EVREAAQKRRAAEDAVYELQSKRLLLERRKPEekvvvqevvvtqkdpkLREEHSRLSGSLDEEVGRRRQLELEVQQLRag 1437
Cdd:TIGR02169  820 KLNRLTLEKEYLEKEIQELQEQRIDLKEQIKS----------------IEKEIENLNGKKEELEEELEELEAALRDLE-- 881
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1438 vEEQEGLLSFQEDRSKKL-AVERELRQLTLRIQELEKRPPTVQEK--IIMEEVVKLEKDPDLEKSTEALRWDLDQEKTQV 1514
Cdd:TIGR02169  882 -SRLGDLKKERDELEAQLrELERKIEELEAQIEKKRKRLSELKAKleALEEELSEIEDPKGEDEEIPEEELSLEDVQAEL 960
                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1002819366 1515 TELNRECKNLQvqiDVLQKAKSQektiYKEVIRVQKDrvLEDERARvwemLNRERTA 1571
Cdd:TIGR02169  961 QRVEEEIRALE---PVNMLAIQE----YEEVLKRLDE--LKEKRAK----LEEERKA 1004
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
928-1153 1.33e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.68  E-value: 1.33e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  928 SPAQAGRESEALKAQLEEERKRVARVQHELEAQRSQLLQLRTQrpLERLEEKEVVEFYRDPQLEGSLSRVKAQVEEEGKR 1007
Cdd:COG4942     14 AAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQ--LAALERRIAALARRIRALEQELAALEAELAELEKE 91
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1008 RAGLQADLEVAAQKVVQL------ESKRKTMQPHLLTKEVTQVERDPG-LDSQAAQLRIQIQQLRGEdaviSARLEGLKK 1080
Cdd:COG4942     92 IAELRAELEAQKEELAELlralyrLGRQPPLALLLSPEDFLDAVRRLQyLKYLAPARREQAEELRAD----LAELAALRA 167
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1002819366 1081 ELLALEKREVDVKEKVVVKEVVKVEKNLEMVKAAQALRLQMEEDAARRKQAEEAVAKLQARIEDLERAISSVE 1153
Cdd:COG4942    168 ELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
994-1385 1.37e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.07  E-value: 1.37e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  994 LSRVKAQVEEEGKRRAGLQADLEVAAQKVVQLESKRKTMQPHLLTKEVTQverdpgldsQAAQLRIQIQQLRGEDAVISA 1073
Cdd:COG4717     76 LEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLL---------QLLPLYQELEALEAELAELPE 146
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1074 RLEGLKKELLA-------LEKREVDVKEKVVVKEVVKVEKNLEMVKAAQALRLQMEEDAARRKQAEEAVAKLQARIEDLE 1146
Cdd:COG4717    147 RLEELEERLEElreleeeLEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELE 226
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1147 RAISSVEPKVIVKEVKKVEQDPGLLQESSRLRSLLEEERTKNATLARELSDLH------SKYSVVEKQRPKVQLQERVHE 1220
Cdd:COG4717    227 EELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLflvlglLALLFLLLAREKASLGKEAEE 306
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1221 IFQVDPETEQEITRLKAKLQEMAGKRSGVEKEVEKLLPDLEvlraqkptvEYKEVTQEVVRHERSpevlREIDRLKAQLN 1300
Cdd:COG4717    307 LQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIE---------ELQELLREAEELEEE----LQLEELEQEIA 373
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1301 ELVNSHG-RSQEQLIRLQGERDEWRRERAKVET--------KTVSKEVVRHEKDPVLEKEAERLRQEVREAAQKRRAAED 1371
Cdd:COG4717    374 ALLAEAGvEDEEELRAALEQAEEYQELKEELEEleeqleelLGELEELLEALDEEELEEELEELEEELEELEEELEELRE 453
                          410
                   ....*....|....
gi 1002819366 1372 AVYELQSKRLLLER 1385
Cdd:COG4717    454 ELAELEAELEQLEE 467
Plectin pfam00681
Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous ...
1710-1738 1.39e-04

Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous pemphigoid antigen.


Pssm-ID: 459901  Cd Length: 39  Bit Score: 40.77  E-value: 1.39e-04
                           10        20
                   ....*....|....*....|....*....
gi 1002819366 1710 ILEPETGKDMSPYEAYKRGIIDRGQYLQL 1738
Cdd:pfam00681   11 IIDPVTGERLSVEEAVKRGLIDPETAQKL 39
PLEC smart00250
Plectin repeat;
1840-1877 2.70e-04

Plectin repeat;


Pssm-ID: 197605  Cd Length: 38  Bit Score: 40.16  E-value: 2.70e-04
                            10        20        30
                    ....*....|....*....|....*....|....*...
gi 1002819366  1840 LGLGDDSFPIAGIYDTTTDNKCSIKTAVAKNMLDPITG 1877
Cdd:smart00250    1 QRLLEAQSAIGGIIDPETGQKLSVEEALRRGLIDPETG 38
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
903-1387 4.59e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.14  E-value: 4.59e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  903 ARKMLEKKELSEDIRRTHDAKQGSespaQAGRESEALKAQLEEERKRVARVQHELEAQRSQLLQLRtqrplERLEEKEVV 982
Cdd:COG4717     54 EADELFKPQGRKPELNLKELKELE----EELKEAEEKEEEYAELQEELEELEEELEELEAELEELR-----EELEKLEKL 124
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  983 EFYRDPQLEgsLSRVKAQVEEEGKRRAGLQADLEVAAQKVVQLESKRKTMQPHLLTKEVTQVERDPGLDSQAAQLRIQIQ 1062
Cdd:COG4717    125 LQLLPLYQE--LEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELE 202
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1063 QLRGEDAVISARLEGLKKELLALEKREVDVKEKVVVKEVVKVEKNLEMVKAAQALRLQMEEDAARRKQAEEAVAKLQAri 1142
Cdd:COG4717    203 ELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLF-- 280
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1143 edLERAISSVEPKVIVKEVKKVEQDPGLLQESSRLRSlLEEERTKNATLARELSDLHSKYSVVEKQRPKVQLQERVHEIF 1222
Cdd:COG4717    281 --LVLGLLALLFLLLAREKASLGKEAEELQALPALEE-LEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAE 357
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1223 QVDPE-TEQEITRLKAKLQEMAGKRSgvEKEVEKLLPDLEvlRAQKPTVEYKEVTQEVVRHERSPEVLREI---DRLKAQ 1298
Cdd:COG4717    358 ELEEElQLEELEQEIAALLAEAGVED--EEELRAALEQAE--EYQELKEELEELEEQLEELLGELEELLEAldeEELEEE 433
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1299 LNELvnshgrsQEQLIRLQGERDEWRRERAKVETKTvsKEVVRHEKDPVLEKEAERLRQEVREAAQKRRAAEDAVYELQS 1378
Cdd:COG4717    434 LEEL-------EEELEELEEELEELREELAELEAEL--EQLEEDGELAELLQELEELKAELRELAEEWAALKLALELLEE 504

                   ....*....
gi 1002819366 1379 KRLLLERRK 1387
Cdd:COG4717    505 AREEYREER 513
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1406-1613 5.19e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.29  E-value: 5.19e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1406 LREEHSRLSGSLDEEVGRRRQLELEVQQLRAGVEEQEGLLSFQEDRSKKLAVERELRQLTLRIQELEKRPPTVQEkiime 1485
Cdd:COG4913    615 LEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREIAELEAELERLDASSDDLAA----- 689
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1486 evvklekdpdLEKSTEALRWDLDQEKTQVTELNRECKNLQVQIDVLQKAKSQEKTIYKEVIRVQKDRVLEDERARVWEML 1565
Cdd:COG4913    690 ----------LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAAL 759
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 1002819366 1566 NRERTARQAREEEarrlreriDRAETLGRTWSREESELQRARDQADQE 1613
Cdd:COG4913    760 GDAVERELRENLE--------ERIDALRARLNRAEEELERAMRAFNRE 799
PTZ00121 PTZ00121
MAEBL; Provisional
808-1081 6.58e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 45.13  E-value: 6.58e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  808 KLQAQKRLTQEIQSRERDRATASHLSQALQAALQDYELQADTYRCSLEPTLAVSAPKRPRVAPLQESIQAQEKNLAKAYT 887
Cdd:PTZ00121  1491 KAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAK 1570
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  888 EVAAAQQQLLQQLEFARKM-------------LEKKELSEDIRRTHDAKQGSESPAQAGRE---SEALKAQLEEERKRVA 951
Cdd:PTZ00121  1571 KAEEDKNMALRKAEEAKKAeearieevmklyeEEKKMKAEEAKKAEEAKIKAEELKKAEEEkkkVEQLKKKEAEEKKKAE 1650
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  952 RVQHELEAQRSQLLQLRTQ-----------RPLERLEEKEVVEFYRDPQLEGSLSRVKAQVEEEGKRRAGLQADLEVAAQ 1020
Cdd:PTZ00121  1651 ELKKAEEENKIKAAEEAKKaeedkkkaeeaKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKI 1730
                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1002819366 1021 KVVQLESKRKTMQphlltKEVTQVERDPGLDSQAAQLRIQIQQLRGE-----DAVISarlEGLKKE 1081
Cdd:PTZ00121  1731 KAEEAKKEAEEDK-----KKAEEAKKDEEEKKKIAHLKKEEEKKAEEirkekEAVIE---EELDEE 1788
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
1071-1712 6.64e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 44.96  E-value: 6.64e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1071 ISARLEGLKKELLALEKREVDVKEKVVVKEVVKVEKNLEMVKAAQALRLQMEEDAARRKQAEEAVAKLQARIEDLERAIS 1150
Cdd:pfam02463  188 LIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKL 267
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1151 SvepKVIVKEVKKVEQDPGLLQESSRLRSLLEEERTKNATLARELSDLHSKYSVVEKQrpKVQLQERVHEIFQVDPETEQ 1230
Cdd:pfam02463  268 A---QVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKE--KKKAEKELKKEKEEIEELEK 342
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1231 EITRLKAKLQEMAGKRSGVEKEVEKLLPDLEVLRAQKpTVEYKEVTQEVVRHErspEVLREIDRLKAQLNELvnsHGRSQ 1310
Cdd:pfam02463  343 ELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKK-KLESERLSSAAKLKE---EELELKSEEEKEAQLL---LELAR 415
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1311 EQLIRLQGERDEWRRERAK----VETKTVSKEVVRHEKDPVLEKEAERLRQEVREAaqKRRAAEDAVYELQSKRLLLERR 1386
Cdd:pfam02463  416 QLEDLLKEEKKEELEILEEeeesIELKQGKLTEEKEELEKQELKLLKDELELKKSE--DLLKETQLVKLQEQLELLLSRQ 493
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1387 KPEEKVVVQEVVVTQKDPKLREEHSRLSGSLDEEVGRRRQLELEVQQLRAGVEEQEGLLSFQEDRSKKLAVERELRQLTL 1466
Cdd:pfam02463  494 KLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTEL 573
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1467 RIQELEKRPPTVQEKIIMEEVVKLEKDPDLEKSTEALRWDLDQEKTQVTELNRECKNLQVQIDVLQKAKSQEKTIYKeVI 1546
Cdd:pfam02463  574 PLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRK-GV 652
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1547 RVQKDRVLEDERARVWEMLNRERTARQAREEEARRLRERIDRAETLGRTWSREESELQRARDQADQECGRLQQELRALER 1626
Cdd:pfam02463  653 SLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQD 732
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1627 QKQQQTLQLQEESKLLSQKTESERQKAAQRGQELSRLEaaiLREKDQIYEKERTLRDLHAKVSREELSQETQTRETNLST 1706
Cdd:pfam02463  733 KINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELS---LKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEE 809

                   ....*.
gi 1002819366 1707 KISILE 1712
Cdd:pfam02463  810 LKEEAE 815
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
1115-1328 6.66e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.37  E-value: 6.66e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1115 QALRLQMEEDAARRKQAEEAVAKLQARIEDLERAISSVEPKVIVKEVKKVEQDPGLLQESSRLRSLLEEERTKNATLARE 1194
Cdd:COG4942     30 EQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAEL 109
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1195 LSDL-----HSKYSVVEKQRPKVQLQERVHEIFQVDPETEQEITRLKAKLQEMAGKRSGVEKEVEKLLPDLEVLRAQKPT 1269
Cdd:COG4942    110 LRALyrlgrQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAA 189
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1002819366 1270 VEykevTQEVVRHERSPEVLREIDRLKAQLNELVNSHGRSQEQLIRLQGERDEWRRERA 1328
Cdd:COG4942    190 LE----ALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTP 244
PLEC smart00250
Plectin repeat;
1954-1991 6.74e-04

Plectin repeat;


Pssm-ID: 197605  Cd Length: 38  Bit Score: 39.00  E-value: 6.74e-04
                            10        20        30
                    ....*....|....*....|....*....|....*...
gi 1002819366  1954 LPHLQVQHLTGGLIDPKRTGRIPIQQALLSGMISEELA 1991
Cdd:smart00250    1 QRLLEAQSAIGGIIDPETGQKLSVEEALRRGLIDPETG 38
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
1125-1388 6.96e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.37  E-value: 6.96e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1125 AARRKQAEEAVAKLQARIEDLERAISSVEpkvivkevkkveqdpgllQESSRLRSLLEEERTKNATLARELSDLHSKYSV 1204
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALK------------------KEEKALLKQLAALERRIAALARRIRALEQELAA 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1205 VEKQRPKVQLQERvheifqvdpETEQEITRLKAKLQEMAGK--RSGVEKEVEKLLPDLEVLRAQKPTVEYKEVTqevvrh 1282
Cdd:COG4942     81 LEAELAELEKEIA---------ELRAELEAQKEELAELLRAlyRLGRQPPLALLLSPEDFLDAVRRLQYLKYLA------ 145
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1283 ersPEVLREIDRLKAQLNELVNSHGRSQEQLIRLQGERDEWRRERAKVETKTVSKEVVRHEkdpvLEKEAERLRQEVREA 1362
Cdd:COG4942    146 ---PARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLAR----LEKELAELAAELAEL 218
                          250       260
                   ....*....|....*....|....*.
gi 1002819366 1363 AQKRRAAEDAVYELQSKRLLLERRKP 1388
Cdd:COG4942    219 QQEAEELEALIARLEAEAAAAAERTP 244
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
1452-1679 8.13e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.98  E-value: 8.13e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1452 SKKLAVERELRQLTLRIQELEKRpptvQEKIIMEEVVKLEKDPDLEKSTEALRWDLDQEKTQVTELNRECKNLQVQIDVL 1531
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKE----LAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAEL 95
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1532 QKAKSQEKTIYKEVIRVQKDRvledERARVWEMLNRERTARQAREEEARRLRERIDRAEtLGRTWSREESELQRARDQAD 1611
Cdd:COG4942     96 RAELEAQKEELAELLRALYRL----GRQPPLALLLSPEDFLDAVRRLQYLKYLAPARRE-QAEELRADLAELAALRAELE 170
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1002819366 1612 QECGRLQQELRALERQKQQQTLQLQEESKL---LSQKTESERQKAAQRGQELSRLEAAILREKDQIYEKER 1679
Cdd:COG4942    171 AERAELEALLAELEEERAALEALKAERQKLlarLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1227-1679 1.34e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.60  E-value: 1.34e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1227 ETEQEITRLKAKLQEMAGKRSGVEKEVEKLLPDLEVLRAQKptvEYKEVTQEVVRHERspevlrEIDRLKAQLNELVNSH 1306
Cdd:COG4717     85 EKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLL---QLLPLYQELEALEA------ELAELPERLEELEERL 155
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1307 GRSQEQLIRLQGERDEWRRERAKVETKTVSKEVVRHEKDPVLEKEAERLRQEVREAAQKRRAAEDAVYELQSKRLLLERR 1386
Cdd:COG4717    156 EELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENE 235
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1387 KPEEkvvvqevvvtQKDPKLREEHSRLSG--------SLDEEVGRRRQLELEVQQLRAGVeeqeGLLSFQEDRSKKLAVE 1458
Cdd:COG4717    236 LEAA----------ALEERLKEARLLLLIaaallallGLGGSLLSLILTIAGVLFLVLGL----LALLFLLLAREKASLG 301
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1459 RELRQLtlriqELEKRPPTVQEKIIMEEVVKLEKDPDLEKStEALRWDLDQEKTQVTELNRECKNLQVQIDVLQKAKSQ- 1537
Cdd:COG4717    302 KEAEEL-----QALPALEELEEEELEELLAALGLPPDLSPE-ELLELLDRIEELQELLREAEELEEELQLEELEQEIAAl 375
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1538 --------EKTIYKEVIRVQKDRVLEDERARVWEMLNRERTARQAREEEARRLRERIDRAETlgrtwSREESELQRARDQ 1609
Cdd:COG4717    376 laeagvedEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEEL-----EEELEELEEELEE 450
                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1610 ADQECGRLQQELRALERQKQQQTLQLQEESKllsqktESERQKAAQRGQELsRLEAAILREKDQIYEKER 1679
Cdd:COG4717    451 LREELAELEAELEQLEEDGELAELLQELEEL------KAELRELAEEWAAL-KLALELLEEAREEYREER 513
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
1350-1740 1.77e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 43.57  E-value: 1.77e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1350 KEAERLRQEVREAAQKRR-AAEDAVYELQSKRLLLERRKPEEKVVVQEVVVTQKDPKLREEHS----RLSGSLDEEVGRR 1424
Cdd:pfam15921   88 KDLQRRLNESNELHEKQKfYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTvhelEAAKCLKEDMLED 167
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1425 RQLELEvqQLRAGVEEQEGLL--------SFQEDRSKKL----------------AVERELRQLTLRIQELEKRPPTVQE 1480
Cdd:pfam15921  168 SNTQIE--QLRKMMLSHEGVLqeirsilvDFEEASGKKIyehdsmstmhfrslgsAISKILRELDTEISYLKGRIFPVED 245
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1481 KIimeEVVKLEKDPDLE-------KSTEALRWDLDQEKTQVTE----LNRECKNLQVQIDVLQKAKSQEKTIYKevirvq 1549
Cdd:pfam15921  246 QL---EALKSESQNKIElllqqhqDRIEQLISEHEVEITGLTEkassARSQANSIQSQLEIIQEQARNQNSMYM------ 316
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1550 kdRVLEDERARVWEMLNRERTARQAREeearrlreriDRAETLGRTWSREESELQRAR---DQADQECG----RLQQELR 1622
Cdd:pfam15921  317 --RQLSDLESTVSQLRSELREAKRMYE----------DKIEELEKQLVLANSELTEARterDQFSQESGnlddQLQKLLA 384
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1623 ALERQKQQQTLQLQEESKLLSQKTESE------RQKAAQRGQELSRLEAAILREKDQIY-EKERTLRDLHAK-VSREELS 1694
Cdd:pfam15921  385 DLHKREKELSLEKEQNKRLWDRDTGNSitidhlRRELDDRNMEVQRLEALLKAMKSECQgQMERQMAAIQGKnESLEKVS 464
                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*.
gi 1002819366 1695 QETQTRETNLSTKISILEPETGKDMSpYEAYKRGIIDRGQYLQLQE 1740
Cdd:pfam15921  465 SLTAQLESTKEMLRKVVEELTAKKMT-LESSERTVSDLTASLQEKE 509
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
1516-1712 1.94e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 43.39  E-value: 1.94e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1516 ELNRECKNLQVQIDVLQKAKSQEKTIYKEVIRVQKDRVLEDERARVWEMLNRERTARQAREEEARRLRERIDRAETLGRT 1595
Cdd:COG1196    217 ELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAE 296
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1596 WSREESELQRARDQADQECGRLQQELRALERQKQQQTLQLQEESKLLSQKTESERQKAAQRgQELSRLEAAILREKDQIY 1675
Cdd:COG1196    297 LARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAE-AELAEAEEALLEAEAELA 375
                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 1002819366 1676 EKERTLRDLHAKVSREELSQ-ETQTRETNLSTKISILE 1712
Cdd:COG1196    376 EAEEELEELAEELLEALRAAaELAAQLEELEEAEEALL 413
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
904-1080 2.31e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.98  E-value: 2.31e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  904 RKMLEKKELSEDIRRTHDAKQGSESPAQAGRESEALKAQLEEERKRVARVQHELEAQRSQLLQLRTQR---PLERLEeke 980
Cdd:COG4913    265 AAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIrgnGGDRLE--- 341
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  981 vvefyrdpQLEGSLSRVKAQVEEEGKRRAGLQADLEVAAQKVVQLESKRKTMQPHLLTKEVTQVERDPGLDSQAAQLRIQ 1060
Cdd:COG4913    342 --------QLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAA 413
                          170       180
                   ....*....|....*....|
gi 1002819366 1061 IQQLRGEDAVISARLEGLKK 1080
Cdd:COG4913    414 LRDLRRELRELEAEIASLER 433
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
1407-1729 2.33e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.13  E-value: 2.33e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1407 REEHSRLSGSLDEEVGRRRQLElEVQQLRAGVEEQEGLLSFQEDRSKKLAVERELRqltLRIQELEKRPPTVQEKIIMEE 1486
Cdd:TIGR02169  156 RKIIDEIAGVAEFDRKKEKALE-ELEEVEENIERLDLIIDEKRQQLERLRREREKA---ERYQALLKEKREYEGYELLKE 231
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1487 VVKLEKD-PDLEKSTEALRWDLDQEKTQVTELNRECKNLQVQIDvlQKAKSQEKTIYKEVIRVQKD-RVLEDERARVWEM 1564
Cdd:TIGR02169  232 KEALERQkEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLE--ELNKKIKDLGEEEQLRVKEKiGELEAEIASLERS 309
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1565 LNRERTARQAREEEARRLRERIDRAETLGRTWSREESELQRARDQADQECGRLQQELRALERqkqqQTLQLQEESKLLSQ 1644
Cdd:TIGR02169  310 IAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRA----ELEEVDKEFAETRD 385
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1645 KTESERQKAAQRGQELSRLEAAILREKDQIYEKERTLRDLHAKVSR-EELSQETQTRETNLSTKISILEPE---TGKDMS 1720
Cdd:TIGR02169  386 ELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGiEAKINELEEEKEDKALEIKKQEWKleqLAADLS 465

                   ....*....
gi 1002819366 1721 PYEAYKRGI 1729
Cdd:TIGR02169  466 KYEQELYDL 474
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1171-1533 2.71e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.83  E-value: 2.71e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1171 LQESSRLRSLLEEERTKNATLARELSDLHSKYSVVEKQRPKVQLQERVHEIFQVDPETEQEITRLKAKLQEMAGKRSGVE 1250
Cdd:COG4717     73 LKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERLEELE 152
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1251 KEVEKLLPDLEVLRAQKPTVEYKEVTQEVVRHERSPEVLREIDRLKAQLNELVNSHGRSQEQLIRLQGERDEWRRERAKV 1330
Cdd:COG4717    153 ERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQL 232
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1331 ETKTVSKEVVRHEKDP-------------------------------------------VLEKEAERLRQEVREAaqKRR 1367
Cdd:COG4717    233 ENELEAAALEERLKEArlllliaaallallglggsllsliltiagvlflvlgllallflLLAREKASLGKEAEEL--QAL 310
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1368 AAEDAVYELQSKRLLLERRKPEEKVVVQEVVVTQKDPKLREEHSRLSgSLDEEVgRRRQLELEVQQL--RAGVEEQEGLL 1445
Cdd:COG4717    311 PALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAE-ELEEEL-QLEELEQEIAALlaEAGVEDEEELR 388
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1446 SFQEDRSKKLAVERELRQLTLRIQELEKRpptvqekiiMEEVVKLEKDPDLEKSTEALRWDLDQEKTQVTELNRECKNLQ 1525
Cdd:COG4717    389 AALEQAEEYQELKEELEELEEQLEELLGE---------LEELLEALDEEELEEELEELEEELEELEEELEELREELAELE 459

                   ....*...
gi 1002819366 1526 VQIDVLQK 1533
Cdd:COG4717    460 AELEQLEE 467
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1292-1705 2.93e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.45  E-value: 2.93e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1292 IDRLKAQLNELVNSHGRsqeQLIRLQGERDEWRRERAKVETKtvskevvrhekdpvlEKEAERLRQEVREAAQKRRAAED 1371
Cdd:COG4717     48 LERLEKEADELFKPQGR---KPELNLKELKELEEELKEAEEK---------------EEEYAELQEELEELEEELEELEA 109
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1372 AVYELQSKRLLLERRKPEEKVVVQEVVVTQKdpkLREEHSRLsGSLDEEVGRRRQLELEVQQLRAGVEEQEGLLSfQEDR 1451
Cdd:COG4717    110 ELEELREELEKLEKLLQLLPLYQELEALEAE---LAELPERL-EELEERLEELRELEEELEELEAELAELQEELE-ELLE 184
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1452 SKKLAVERELRQLTLRIQELEKRPPTVQEKIIMEEVVKLEKDPDLEKSTEALRWDLDQEKTQVTELNRECKNLQVQIDVL 1531
Cdd:COG4717    185 QLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGL 264
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1532 QKAKSQEKTIYKEVIRVQKDRVLEDERARVWEMLNRERTARQAREEEARRLRERIDRAETLGRTWSREESELQRARDQAD 1611
Cdd:COG4717    265 GGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLD 344
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1612 --QECGRLQQELRALERQKQQQTLQLQEESKLLSQKTESERQ--KAAQRGQELSRLEAAILREKDQIYEKERTLRDLHAK 1687
Cdd:COG4717    345 riEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEElrAALEQAEEYQELKEELEELEEQLEELLGELEELLEA 424
                          410
                   ....*....|....*...
gi 1002819366 1688 VSREELSQETQTRETNLS 1705
Cdd:COG4717    425 LDEEELEEELEELEEELE 442
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
939-1708 3.20e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 42.85  E-value: 3.20e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366  939 LKAQLEEERKRVARVQHELEAQRSQLLQLRTQR--PLERLEEKE--VVEFYRDPQLE-GSLSRVKAQVEEEGKRRAGLQA 1013
Cdd:pfam01576  227 LQAQIAELRAQLAKKEEELQAALARLEEETAQKnnALKKIRELEaqISELQEDLESErAARNKAEKQRRDLGEELEALKT 306
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1014 DLE-----VAAQKvvQLESKRKTmqphlltkEVTQVERdpGLDSQAAQLRIQIQQLRGEDAV----ISARLEGLKKELLA 1084
Cdd:pfam01576  307 ELEdtldtTAAQQ--ELRSKREQ--------EVTELKK--ALEEETRSHEAQLQEMRQKHTQaleeLTEQLEQAKRNKAN 374
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1085 LEKrevdvkekvvvKEVVKVEKNLEMVKAAQALRLQMEEDAARRKQAEEAVAKLQARIEDLERAISSVEPKVIVkevkkv 1164
Cdd:pfam01576  375 LEK-----------AKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSK------ 437
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1165 eqdpgLLQESSRLRSLLEEERTKNATLARELSDLHSKYSVV-----EKQRPKVQLQERVHEIfqvdpetEQEITRLKAKL 1239
Cdd:pfam01576  438 -----LQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTqellqEETRQKLNLSTRLRQL-------EDERNSLQEQL 505
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1240 QEMAGKRSGVEKEVEKLLPDLEVLRAQkptVEYKEVTQEVVRHERSpEVLREIDRLKAQLNELVNSHGRSQEQLIRLQGE 1319
Cdd:pfam01576  506 EEEEEAKRNVERQLSTLQAQLSDMKKK---LEEDAGTLEALEEGKK-RLQRELEALTQQLEEKAAAYDKLEKTKNRLQQE 581
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1320 RDEWRRERAKVETKTVSKEVVRHEKDPVLEKEaerlRQEVREAAQKRRAAEDAVYELQSKRLLLERRKPEEKVVVQEVVV 1399
Cdd:pfam01576  582 LDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEE----KAISARYAEERDRAEAEAREKETRALSLARALEEALEAKEELER 657
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1400 TQKdpKLREEHSRLSGSLDEeVGR--------RRQLELEVQQLRAGVEEQEGLLSFQEDRSKKLAV---------EREL- 1461
Cdd:pfam01576  658 TNK--QLRAEMEDLVSSKDD-VGKnvhelersKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVnmqalkaqfERDLq 734
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1462 ----------RQLTLRIQELEKR--PPTVQEKIIMEEVVKLEKD-PDLEKSTEALRWDLDQEKTQVTELNRECKNLQVQI 1528
Cdd:pfam01576  735 ardeqgeekrRQLVKQVRELEAEleDERKQRAQAVAAKKKLELDlKELEAQIDAANKGREEAVKQLKKLQAQMKDLQREL 814
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1529 DVLQKAKSQEKTIYKEVIRvqKDRVLEDERARVWEMLNRERTARQAREEEARRLRERIDRAETLGRTWSREESELQRARD 1608
Cdd:pfam01576  815 EEARASRDEILAQSKESEK--KLKNLEAELLQLQEDLAASERARRQAQQERDELADEIASGASGKSALQDEKRRLEARIA 892
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1609 QADQECGRLQQELRAL-ERQKQQQTLQLQEESKL-----LSQKTESERQKAAQRGQELSrleAAILREKDQIYEKER-TL 1681
Cdd:pfam01576  893 QLEEELEEEQSNTELLnDRLRKSTLQVEQLTTELaaersTSQKSESARQQLERQNKELK---AKLQEMEGTVKSKFKsSI 969
                          810       820
                   ....*....|....*....|....*..
gi 1002819366 1682 RDLHAKVSREELSQETQTRETNLSTKI 1708
Cdd:pfam01576  970 AALEAKIAQLEEQLEQESRERQAANKL 996
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
1349-1750 4.54e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 42.27  E-value: 4.54e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1349 EKEAERLRQEVREAAQKRRAAEDAVYELQSKRLLLERRKpeekvVVQEVVVTQKDPKLREEHSRLsgsLDEEVGRRRQLE 1428
Cdd:pfam02463  169 RKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAK-----KALEYYQLKEKLELEEEYLLY---LDYLKLNEERID 240
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1429 LEVQQLRAGVEEQEGLLSFQEDRSKKLAVERELRQLTLRIQELEKRPPTVQEKIIMEEVVKLEKdpdLEKSTEALRWDLD 1508
Cdd:pfam02463  241 LLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLK---LERRKVDDEEKLK 317
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1509 QEKTQVTELNRECKNLQVQIDVLQKAKS--QEKTIYKEVIRVQKDRVLEDERARVWEMLNRERTARQAREEEARRLRERI 1586
Cdd:pfam02463  318 ESEKEKKKAEKELKKEKEEIEELEKELKelEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEEL 397
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1587 DRAETLGRTWSREESELQRARDQADqecgRLQQELRALERQKQQQTLQLQEESKLLSQKTESERQKAAQRGQELSRLEAA 1666
Cdd:pfam02463  398 ELKSEEEKEAQLLLELARQLEDLLK----EEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDL 473
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1667 ILREKDQIYEKERTLRDLHAKVsREELSQETQTRETNLSTKISILEPETGKDMSPYEAYKRGIIDRGQYLQLQELECDWE 1746
Cdd:pfam02463  474 LKETQLVKLQEQLELLLSRQKL-EERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVE 552

                   ....
gi 1002819366 1747 EVTT 1750
Cdd:pfam02463  553 VSAT 556
PLEC smart00250
Plectin repeat;
1710-1735 5.32e-03

Plectin repeat;


Pssm-ID: 197605  Cd Length: 38  Bit Score: 36.31  E-value: 5.32e-03
                            10        20
                    ....*....|....*....|....*.
gi 1002819366  1710 ILEPETGKDMSPYEAYKRGIIDRGQY 1735
Cdd:smart00250   13 IIDPETGQKLSVEEALRRGLIDPETG 38
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
1180-1719 6.02e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 41.75  E-value: 6.02e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1180 LLEEERTKNATLARELSDLHSKYsvVEKQRPKVQLQERVHEI-----FQVDPETEQeitrLKAKLQEMAGKRSGVEKEVE 1254
Cdd:pfam12128  245 KLQQEFNTLESAELRLSHLHFGY--KSDETLIASRQEERQETsaelnQLLRTLDDQ----WKEKRDELNGELSAADAAVA 318
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1255 KLLPDLEVLRAQKPTVEYKEVTQEVVRHERSPEVLREIDRLKAQLNELVNSHGRSQEqlirlqgerdEWRRERAKVETKT 1334
Cdd:pfam12128  319 KDRSELEALEDQHGAFLDADIETAAADQEQLPSWQSELENLEERLKALTGKHQDVTA----------KYNRRRSKIKEQN 388
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1335 VSKEVVRHEKdpvlekeaerlRQEVREAAQKRRAAEDAVYELQSKRLllerrkpeekvvvqEVVVTQKDPKLREEHSRLS 1414
Cdd:pfam12128  389 NRDIAGIKDK-----------LAKIREARDRQLAVAEDDLQALESEL--------------REQLEAGKLEFNEEEYRLK 443
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1415 GSLDEEVGRRRQL---ELEVQQLRAGVEEQEGLLSFQEDRSKK-LAVERELRQL-TLRIQELEKR---PPTVQEKIIMEE 1486
Cdd:pfam12128  444 SRLGELKLRLNQAtatPELLLQLENFDERIERAREEQEAANAEvERLQSELRQArKRRDQASEALrqaSRRLEERQSALD 523
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1487 VVKLEKDPDLEK-----STEALRWDLDQEKTQVTELNRECknlQVQIDVLQKAKSQEKTIYKEVIRVQKDRV-------- 1553
Cdd:pfam12128  524 ELELQLFPQAGTllhflRKEAPDWEQSIGKVISPELLHRT---DLDPEVWDGSVGGELNLYGVKLDLKRIDVpewaasee 600
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1554 -LEDERARVWEMLNRERTARQAREEEARRLRERIDRAetlgrtwSREESELQRARDQADQECGRLQQELRALERQKQQQT 1632
Cdd:pfam12128  601 eLRERLDKAEEALQSAREKQAAAEEQLVQANGELEKA-------SREETFARTALKNARLDLRRLFDEKQSEKDKKNKAL 673
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002819366 1633 LQLQEeskllsQKTESERQKAAQRGQELSRLEAAILREKDQIYEkERTLRDLHAKVSREE-------LSQETQTRETNLS 1705
Cdd:pfam12128  674 AERKD------SANERLNSLEAQLKQLDKKHQAWLEEQKEQKRE-ARTEKQAYWQVVEGAldaqlalLKAAIAARRSGAK 746
                          570
                   ....*....|....
gi 1002819366 1706 TKISILEPETGKDM 1719
Cdd:pfam12128  747 AELKALETWYKRDL 760
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH
HHS Vulnerability Disclosure