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Conserved domains on  [gi|1019367017|ref|NP_001310151|]
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mimecan precursor [Coturnix japonica]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 1001123)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions; similar to Oryctolagus cuniculus monocyte differentiation antigen CD14, a coreceptor for bacterial lipopolysaccharide

Gene Ontology:  GO:0005515
PubMed:  11751054

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LRR super family cl34836
Leucine-rich repeat (LRR) protein [Transcription];
118-244 5.05e-09

Leucine-rich repeat (LRR) protein [Transcription];


The actual alignment was detected with superfamily member COG4886:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 56.48  E-value: 5.05e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1019367017 118 YLYARFNKIKRIAvSDFADITTLRRIDFSGNMIEEIEDGafsklllleelslaenrLVKLPvlppKLTTFNANQNRIKSr 197
Cdd:COG4886   140 ELDLSNNQLTDLP-EPLGNLTNLKSLDLSNNQLTDLPEE-----------------LGNLT----NLKELDLSNNQITD- 196

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 1019367017 198 gIKNnAFKKLTNLAYLYLGHNALESVPLNLPE--SLRILHLQHNNITTI 244
Cdd:COG4886   197 -LPE-PLGNLTNLEELDLSGNQLTDLPEPLANltNLETLDLSNNQLTDL 243
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
118-244 5.05e-09

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 56.48  E-value: 5.05e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1019367017 118 YLYARFNKIKRIAvSDFADITTLRRIDFSGNMIEEIEDGafsklllleelslaenrLVKLPvlppKLTTFNANQNRIKSr 197
Cdd:COG4886   140 ELDLSNNQLTDLP-EPLGNLTNLKSLDLSNNQLTDLPEE-----------------LGNLT----NLKELDLSNNQITD- 196

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 1019367017 198 gIKNnAFKKLTNLAYLYLGHNALESVPLNLPE--SLRILHLQHNNITTI 244
Cdd:COG4886   197 -LPE-PLGNLTNLEELDLSGNQLTDLPEPLANltNLETLDLSNNQLTDL 243
LRR_8 pfam13855
Leucine rich repeat;
182-241 3.98e-07

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 46.36  E-value: 3.98e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1019367017 182 PKLTTFNANQNRIKSrgIKNNAFKKLTNLAYLYLGHNALESVPLN----LPeSLRILHLQHNNI 241
Cdd:pfam13855   1 PNLRSLDLSNNRLTS--LDDGAFKGLSNLKVLDLSNNLLTTLSPGafsgLP-SLRYLDLSGNRL 61
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
69-241 5.21e-06

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 47.77  E-value: 5.21e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1019367017  69 LQADDSELSARPTKDTNLPTCLlcvclSGSVYCEEIDIEAVPPLPKET----AYLYARFNKIKRIAvSDFADitTLRRID 144
Cdd:PRK15370  218 LQGNIKTLYANSNQLTSIPATL-----PDTIQEMELSINRITELPERLpsalQSLDLFHNKISCLP-ENLPE--ELRYLS 289

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1019367017 145 FSGNMIEEIEDGAFSKLLLLEELSlaeNRLVKLP-VLPPKLTTFNANQN-----------RIKSRGIKNNAFKKLT---- 208
Cdd:PRK15370  290 VYDNSIRTLPAHLPSGITHLNVQS---NSLTALPeTLPPGLKTLEAGENaltslpaslppELQVLDVSKNQITVLPetlp 366

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1019367017 209 -NLAYLYLGHNALESVPLNLPESLRILHLQHNNI 241
Cdd:PRK15370  367 pTITTLDVSRNALTNLPENLPAALQIMQASRNNL 400
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
118-244 5.05e-09

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 56.48  E-value: 5.05e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1019367017 118 YLYARFNKIKRIAvSDFADITTLRRIDFSGNMIEEIEDGafsklllleelslaenrLVKLPvlppKLTTFNANQNRIKSr 197
Cdd:COG4886   140 ELDLSNNQLTDLP-EPLGNLTNLKSLDLSNNQLTDLPEE-----------------LGNLT----NLKELDLSNNQITD- 196

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 1019367017 198 gIKNnAFKKLTNLAYLYLGHNALESVPLNLPE--SLRILHLQHNNITTI 244
Cdd:COG4886   197 -LPE-PLGNLTNLEELDLSGNQLTDLPEPLANltNLETLDLSNNQLTDL 243
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
118-254 1.60e-07

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 52.24  E-value: 1.60e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1019367017 118 YLYARFNKIKRIAVSdFADITTLRRIDFSGNMIEEIEDgAFSKLLLLEELSLAENRLVKLPV-LP--PKLTTFNANQNRI 194
Cdd:COG4886   163 SLDLSNNQLTDLPEE-LGNLTNLKELDLSNNQITDLPE-PLGNLTNLEELDLSGNQLTDLPEpLAnlTNLETLDLSNNQL 240

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1019367017 195 KSrgIKNnaFKKLTNLAYLYLGHNALESVP--LNLPeSLRILHLQHNNITTITDDTFCKSNN 254
Cdd:COG4886   241 TD--LPE--LGNLTNLEELDLSNNQLTDLPplANLT-NLKTLDLSNNQLTDLKLKELELLLG 297
LRR_8 pfam13855
Leucine rich repeat;
182-241 3.98e-07

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 46.36  E-value: 3.98e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1019367017 182 PKLTTFNANQNRIKSrgIKNNAFKKLTNLAYLYLGHNALESVPLN----LPeSLRILHLQHNNI 241
Cdd:pfam13855   1 PNLRSLDLSNNRLTS--LDDGAFKGLSNLKVLDLSNNLLTTLSPGafsgLP-SLRYLDLSGNRL 61
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
132-246 1.60e-06

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 49.16  E-value: 1.60e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1019367017 132 SDFADITTLRRIDFSGNMIEEIEDGafsklllleelslaenrLVKLPvlppKLTTFNANQNRIKSRGiknNAFKKLTNLA 211
Cdd:COG4886   107 EELSNLTNLESLDLSGNQLTDLPEE-----------------LANLT----NLKELDLSNNQLTDLP---EPLGNLTNLK 162

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1019367017 212 YLYLGHNALESVP---LNLPeSLRILHLQHNNITTITD 246
Cdd:COG4886   163 SLDLSNNQLTDLPeelGNLT-NLKELDLSNNQITDLPE 199
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
69-241 5.21e-06

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 47.77  E-value: 5.21e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1019367017  69 LQADDSELSARPTKDTNLPTCLlcvclSGSVYCEEIDIEAVPPLPKET----AYLYARFNKIKRIAvSDFADitTLRRID 144
Cdd:PRK15370  218 LQGNIKTLYANSNQLTSIPATL-----PDTIQEMELSINRITELPERLpsalQSLDLFHNKISCLP-ENLPE--ELRYLS 289

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1019367017 145 FSGNMIEEIEDGAFSKLLLLEELSlaeNRLVKLP-VLPPKLTTFNANQN-----------RIKSRGIKNNAFKKLT---- 208
Cdd:PRK15370  290 VYDNSIRTLPAHLPSGITHLNVQS---NSLTALPeTLPPGLKTLEAGENaltslpaslppELQVLDVSKNQITVLPetlp 366

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1019367017 209 -NLAYLYLGHNALESVPLNLPESLRILHLQHNNI 241
Cdd:PRK15370  367 pTITTLDVSRNALTNLPENLPAALQIMQASRNNL 400
LRR_8 pfam13855
Leucine rich repeat;
208-272 3.96e-05

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 40.59  E-value: 3.96e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1019367017 208 TNLAYLYLGHNALESVP----LNLPeSLRILHLQHNNITTITDDTFCKSNNTRYirtrmdeIRMEGNPI 272
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDdgafKGLS-NLKVLDLSNNLLTTLSPGAFSGLPSLRY-------LDLSGNRL 61
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
119-246 5.17e-05

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 44.69  E-value: 5.17e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1019367017 119 LYARFNKIKRIAVSdFADitTLRRIDFSGNMIEEIEDGAFSkllLLEELSLAENRLVKLP-VLPPKLTTFNANQNRIKSR 197
Cdd:PRK15370  225 LYANSNQLTSIPAT-LPD--TIQEMELSINRITELPERLPS---ALQSLDLFHNKISCLPeNLPEELRYLSVYDNSIRTL 298

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1019367017 198 -----------GIKNNAFKKL-----TNLAYLYLGHNALESVPLNLPESLRILHLQHNNITTITD 246
Cdd:PRK15370  299 pahlpsgithlNVQSNSLTALpetlpPGLKTLEAGENALTSLPASLPPELQVLDVSKNQITVLPE 363
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
118-255 8.08e-05

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 43.77  E-value: 8.08e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1019367017 118 YLYARFNKIKRIAVSdFADITTLRRIDFSGNMIEEIEDgAFSKLLLLEELSLAENRLVKLPVLP--PKLTTFNANQNRIK 195
Cdd:COG4886   186 ELDLSNNQITDLPEP-LGNLTNLEELDLSGNQLTDLPE-PLANLTNLETLDLSNNQLTDLPELGnlTNLEELDLSNNQLT 263

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1019367017 196 SrgIKNNAfkKLTNLAYLYLGHNALESVPLNLPESLRILHLQHNNITTITDDTFCKSNNT 255
Cdd:COG4886   264 D--LPPLA--NLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLL 319
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
172-288 2.46e-04

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 42.38  E-value: 2.46e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1019367017 172 NRLVKLP-VLPPKLTTFNANQNRIKSRGiknnafKKL-TNLAYLYLGHNALESVPLNLPESLRILHLQHNNITTITD--- 246
Cdd:PRK15370  230 NQLTSIPaTLPDTIQEMELSINRITELP------ERLpSALQSLDLFHNKISCLPENLPEELRYLSVYDNSIRTLPAhlp 303

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1019367017 247 ----DTFCKSNNTryirTRMDEIRMEGNPILLAKHvNAFSCL-KTLP 288
Cdd:PRK15370  304 sgitHLNVQSNSL----TALPETLPPGLKTLEAGE-NALTSLpASLP 345
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
159-244 2.84e-04

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 42.23  E-value: 2.84e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1019367017 159 SKLLLLEELSLAENRLVKLPVLPPKLTTFNANQNRIKSRGIKNNAFKKLTNLAYLYLGHNALESVPLNLPE--SLRILHL 236
Cdd:COG4886    64 SLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNEELSNLTNLESLDLSGNQLTDLPEELANltNLKELDL 143


                  ....*...
gi 1019367017 237 QHNNITTI 244
Cdd:COG4886   144 SNNQLTDL 151
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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