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Conserved domains on  [gi|1045561573|ref|NP_001316570|]
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protein Spindly isoform b [Homo sapiens]

Protein Classification

coiled-coil domain-containing protein( domain architecture ID 1000037)

coiled-coil domain-containing protein contains a region with alpha-helical coiled-coil sequence signatures that is being annotated by a variety of protein family models, not necessarily indicating family membership

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 4-337 1.40e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.02  E-value: 1.40e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573   4 DIITNLRCRLKEAEEERLKAAQYglqlvesqNELQNQLDKCRNEMMTMT-ESYEQEKYTLQREVELKSRMLESLSCE--- 79
Cdd:COG1196   193 DILGELERQLEPLERQAEKAERY--------RELKEELKELEAELLLLKlRELEAELEELEAELEELEAELEELEAElae 264

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573  80 CEAIKQQQKMHLEKLEEQLS------RSHGQEVNELKTKIEKLKVELDEARLSEKQLKHQVDHQKELLSCKSEELRVMSE 153
Cdd:COG1196   265 LEAELEELRLELEELELELEeaqaeeYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEE 344

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573 154 RVQESmSSEMLALQIELTEMESMKTTLKEEVNELQYRQEQLELLITNLMRQVDRLKEEKEEREKEAVSYYNALEKARVAN 233
Cdd:COG1196   345 ELEEA-EEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEEL 423

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573 234 QDLQVQLDQALQ---QALDPNSKGNSLFAEVEDRRAAMERQLISMKVKYQSLKKQNVFNREQMQRMKLQIATLLQMKGSQ 310
Cdd:COG1196   424 EELEEALAELEEeeeEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503

                         330       340
                  ....*....|....*....|....*..
gi 1045561573 311 TEFEQQERLLAMLEQKNGEIKHLLGEI 337
Cdd:COG1196   504 EGFLEGVKAALLLAGLRGLAGAVAVLI 530
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 4-337 1.40e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.02  E-value: 1.40e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573   4 DIITNLRCRLKEAEEERLKAAQYglqlvesqNELQNQLDKCRNEMMTMT-ESYEQEKYTLQREVELKSRMLESLSCE--- 79
Cdd:COG1196   193 DILGELERQLEPLERQAEKAERY--------RELKEELKELEAELLLLKlRELEAELEELEAELEELEAELEELEAElae 264

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573  80 CEAIKQQQKMHLEKLEEQLS------RSHGQEVNELKTKIEKLKVELDEARLSEKQLKHQVDHQKELLSCKSEELRVMSE 153
Cdd:COG1196   265 LEAELEELRLELEELELELEeaqaeeYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEE 344

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573 154 RVQESmSSEMLALQIELTEMESMKTTLKEEVNELQYRQEQLELLITNLMRQVDRLKEEKEEREKEAVSYYNALEKARVAN 233
Cdd:COG1196   345 ELEEA-EEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEEL 423

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573 234 QDLQVQLDQALQ---QALDPNSKGNSLFAEVEDRRAAMERQLISMKVKYQSLKKQNVFNREQMQRMKLQIATLLQMKGSQ 310
Cdd:COG1196   424 EELEEALAELEEeeeEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503

                         330       340
                  ....*....|....*....|....*..
gi 1045561573 311 TEFEQQERLLAMLEQKNGEIKHLLGEI 337
Cdd:COG1196   504 EGFLEGVKAALLLAGLRGLAGAVAVLI 530
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 84-353 3.27e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 53.52  E-value: 3.27e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573   84 KQQQKMHLEKLEEQLSRShGQEVNELKTKIEKLKVELDEARLSEKQLKHQVDH-QKELLSCKSE------ELRVMSERvQ 156
Cdd:TIGR02168  234 LEELREELEELQEELKEA-EEELEELTAELQELEEKLEELRLEVSELEEEIEElQKELYALANEisrleqQKQILRER-L 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573  157 ESMSSEMLALQIELTEMESMKTTLKEEVNELQYRQEQLELLITNLMRQVDRLKeekeerekeavsyyNALEKARVANQDL 236
Cdd:TIGR02168  312 ANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELE--------------AELEELESRLEEL 377

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573  237 QVQLDQAlqqaldpnskgNSLFAEVEDRRAAMERQLISMKVKYQSLKKqNVFNREQMQRMKLQIATLLQMKGSQTEFEQQ 316
Cdd:TIGR02168  378 EEQLETL-----------RSKVAQLELQIASLNNEIERLEARLERLED-RRERLQQEIEELLKKLEEAELKELQAELEEL 445

                          250       260       270
                   ....*....|....*....|....*....|....*...
gi 1045561573  317 ERLLAMLEQKNGEIKHLLGEIRN-LEKFKNLYDSMESK 353
Cdd:TIGR02168  446 EEELEELQEELERLEEALEELREeLEEAEQALDAAERE 483
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 22-439 8.11e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 48.96  E-value: 8.11e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573   22 KAAQYGLQLVESQNELQNQLDKCRNEMMTMtESYEQEKYTLQREVELKSRMLESLSCECEAIKQQQKMHLEKLeeQLSRS 101
Cdd:pfam15921  462 KVSSLTAQLESTKEMLRKVVEELTAKKMTL-ESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQEL--QHLKN 538

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573  102 HGQEVNELKTKIEKLKVELDEARLSEKQLKHQVDHQKELLSckseelrvmservQESMSSEmlALQIEltemesmKTTLK 181
Cdd:pfam15921  539 EGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVG-------------QHGRTAG--AMQVE-------KAQLE 596

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573  182 EEVNELQYRQEQLELLITNLMRQVDRLKEEKEEREKEAVSYYNALEKARVANQDLQVQLDQALQQALDPNSKGNSLFAEv 261
Cdd:pfam15921  597 KEINDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSED- 675

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573  262 edrraamerqlismkvkYQSLKKQNVFNREQMQRMKLQIAtlLQMKGSQTEFEQQERLLAMLEQKNGE-IKHLLGEIRNL 340
Cdd:pfam15921  676 -----------------YEVLKRNFRNKSEEMETTTNKLK--MQLKSAQSELEQTRNTLKSMEGSDGHaMKVAMGMQKQI 736

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573  341 EKFKNLYDSMESKPSVDSGTLEDNTYYTDLLQMKLDNLNKEIEST-------KGELSIQRMKALFESQRALDIERKLfaN 413
Cdd:pfam15921  737 TAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVateknkmAGELEVLRSQERRLKEKVANMEVAL--D 814

                          410       420
                   ....*....|....*....|....*.
gi 1045561573  414 ERCLQLSESENMKLRAKLDELKLKYE 439
Cdd:pfam15921  815 KASLQFAECQDIIQRQEQESVRLKLQ 840
PRK11281 PRK11281
mechanosensitive channel MscK;
23-316 2.86e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 44.13  E-value: 2.86e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573   23 AAQYGLQLVESQNELQNQLDKcrnemMTMTESYEQEKYTLQREVELKSRMLESlsceceaiKQQQKMHLEKLEEQLSRSH 102
Cdd:PRK11281    27 ARAASNGDLPTEADVQAQLDA-----LNKQKLLEAEDKLVQQDLEQTLALLDK--------IDRQKEETEQLKQQLAQAP 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573  103 gQEVNELKTKIEKLKVELDE------ARLSEKQLKHQV--------DHQKELLSCKSE--ELRVMSERVQESMSSEMLAL 166
Cdd:PRK11281    94 -AKLRQAQAELEALKDDNDEetretlSTLSLRQLESRLaqtldqlqNAQNDLAEYNSQlvSLQTQPERAQAALYANSQRL 172

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573  167 QiELTEM-----ESMKTTLKEEVNELQYRQEQLELLI---TNLMRQVDRLKEEKEEREKEAVSYYNALEKARVANQDL-- 236
Cdd:PRK11281   173 Q-QIRNLlkggkVGGKALRPSQRVLLQAEQALLNAQNdlqRKSLEGNTQLQDLLQKQRDYLTARIQRLEHQLQLLQEAin 251

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573  237 -------QVQLDQALQQALDPNSKGNSLFAEVEDRRAAMERQLISMKVKYQSLKKQNVfnreqmqRMKLQIATLLQmkgS 309
Cdd:PRK11281   252 skrltlsEKTVQEAQSQDEAARIQANPLVAQELEINLQLSQRLLKATEKLNTLTQQNL-------RVKNWLDRLTQ---S 321


                   ....*..
gi 1045561573  310 QTEFEQQ 316
Cdd:PRK11281   322 ERNIKEQ 328
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 4-337 1.40e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.02  E-value: 1.40e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573   4 DIITNLRCRLKEAEEERLKAAQYglqlvesqNELQNQLDKCRNEMMTMT-ESYEQEKYTLQREVELKSRMLESLSCE--- 79
Cdd:COG1196   193 DILGELERQLEPLERQAEKAERY--------RELKEELKELEAELLLLKlRELEAELEELEAELEELEAELEELEAElae 264

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573  80 CEAIKQQQKMHLEKLEEQLS------RSHGQEVNELKTKIEKLKVELDEARLSEKQLKHQVDHQKELLSCKSEELRVMSE 153
Cdd:COG1196   265 LEAELEELRLELEELELELEeaqaeeYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEE 344

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573 154 RVQESmSSEMLALQIELTEMESMKTTLKEEVNELQYRQEQLELLITNLMRQVDRLKEEKEEREKEAVSYYNALEKARVAN 233
Cdd:COG1196   345 ELEEA-EEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEEL 423

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573 234 QDLQVQLDQALQ---QALDPNSKGNSLFAEVEDRRAAMERQLISMKVKYQSLKKQNVFNREQMQRMKLQIATLLQMKGSQ 310
Cdd:COG1196   424 EELEEALAELEEeeeEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503

                         330       340
                  ....*....|....*....|....*..
gi 1045561573 311 TEFEQQERLLAMLEQKNGEIKHLLGEI 337
Cdd:COG1196   504 EGFLEGVKAALLLAGLRGLAGAVAVLI 530
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 84-353 3.27e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 53.52  E-value: 3.27e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573   84 KQQQKMHLEKLEEQLSRShGQEVNELKTKIEKLKVELDEARLSEKQLKHQVDH-QKELLSCKSE------ELRVMSERvQ 156
Cdd:TIGR02168  234 LEELREELEELQEELKEA-EEELEELTAELQELEEKLEELRLEVSELEEEIEElQKELYALANEisrleqQKQILRER-L 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573  157 ESMSSEMLALQIELTEMESMKTTLKEEVNELQYRQEQLELLITNLMRQVDRLKeekeerekeavsyyNALEKARVANQDL 236
Cdd:TIGR02168  312 ANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELE--------------AELEELESRLEEL 377

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573  237 QVQLDQAlqqaldpnskgNSLFAEVEDRRAAMERQLISMKVKYQSLKKqNVFNREQMQRMKLQIATLLQMKGSQTEFEQQ 316
Cdd:TIGR02168  378 EEQLETL-----------RSKVAQLELQIASLNNEIERLEARLERLED-RRERLQQEIEELLKKLEEAELKELQAELEEL 445

                          250       260       270
                   ....*....|....*....|....*....|....*...
gi 1045561573  317 ERLLAMLEQKNGEIKHLLGEIRN-LEKFKNLYDSMESK 353
Cdd:TIGR02168  446 EEELEELQEELERLEEALEELREeLEEAEQALDAAERE 483
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 22-439 8.11e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 48.96  E-value: 8.11e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573   22 KAAQYGLQLVESQNELQNQLDKCRNEMMTMtESYEQEKYTLQREVELKSRMLESLSCECEAIKQQQKMHLEKLeeQLSRS 101
Cdd:pfam15921  462 KVSSLTAQLESTKEMLRKVVEELTAKKMTL-ESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQEL--QHLKN 538

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573  102 HGQEVNELKTKIEKLKVELDEARLSEKQLKHQVDHQKELLSckseelrvmservQESMSSEmlALQIEltemesmKTTLK 181
Cdd:pfam15921  539 EGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVG-------------QHGRTAG--AMQVE-------KAQLE 596

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573  182 EEVNELQYRQEQLELLITNLMRQVDRLKEEKEEREKEAVSYYNALEKARVANQDLQVQLDQALQQALDPNSKGNSLFAEv 261
Cdd:pfam15921  597 KEINDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSED- 675

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573  262 edrraamerqlismkvkYQSLKKQNVFNREQMQRMKLQIAtlLQMKGSQTEFEQQERLLAMLEQKNGE-IKHLLGEIRNL 340
Cdd:pfam15921  676 -----------------YEVLKRNFRNKSEEMETTTNKLK--MQLKSAQSELEQTRNTLKSMEGSDGHaMKVAMGMQKQI 736

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573  341 EKFKNLYDSMESKPSVDSGTLEDNTYYTDLLQMKLDNLNKEIEST-------KGELSIQRMKALFESQRALDIERKLfaN 413
Cdd:pfam15921  737 TAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVateknkmAGELEVLRSQERRLKEKVANMEVAL--D 814

                          410       420
                   ....*....|....*....|....*.
gi 1045561573  414 ERCLQLSESENMKLRAKLDELKLKYE 439
Cdd:pfam15921  815 KASLQFAECQDIIQRQEQESVRLKLQ 840
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
12-208 9.97e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 48.76  E-value: 9.97e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573   12 RLKEAEEERLKA-AQYGL--QLVESQNELQNQLDKCR--NEMMTMTESY--EQEKYTLQREVELKSRMLESLSCECEAIK 84
Cdd:COG4913    236 DLERAHEALEDArEQIELlePIRELAERYAAARERLAelEYLRAALRLWfaQRRLELLEAELEELRAELARLEAELERLE 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573   85 QQ---QKMHLEKLEEQLSRSHGQEVNELKTKIEKLKVELDEARLSEKQLKHQVDHQKELLSCKSEELRVMSERVQ---ES 158
Cdd:COG4913    316 ARldaLREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAallEA 395

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|
gi 1045561573  159 MSSEMLALQIELTEMESMKTTLKEEVNELQYRQEQLELLITNLMRQVDRL 208
Cdd:COG4913    396 LEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLAL 445
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 56-268 4.52e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.91  E-value: 4.52e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573  56 EQEKYTLQREVELKSRMLESLSCECEAIKQQqkmhLEKLEEQLSRSHgQEVNELKTKIEKLKVELDEARLSEKQLKHQVD 135
Cdd:COG4942    26 EAELEQLQQEIAELEKELAALKKEEKALLKQ----LAALERRIAALA-RRIRALEQELAALEAELAELEKEIAELRAELE 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573 136 HQKELLScksEELRVM--------------------SERVQESMSSEMLALQIELTEMESMKTTLKEEVNELQYRQEQLE 195
Cdd:COG4942   101 AQKEELA---ELLRALyrlgrqpplalllspedfldAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELE 177

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1045561573 196 LLITNLMRQVDRLKEEKEEREKeavsyynALEKARVANQDLQVQLDQALQQALDPNSKGNSLFAEVEDRRAAM 268
Cdd:COG4942   178 ALLAELEEERAALEALKAERQK-------LLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 6-339 7.32e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.82  E-value: 7.32e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573    6 ITNLRCRLKEAEEERLKAAqyglqlvESQNELQNQLDKCRNEmmtmTESYEQEKYTLQREVELKSRMLESLSCECEAIKQ 85
Cdd:TIGR02168  672 ILERRREIEELEEKIEELE-------EKIAELEKALAELRKE----LEELEEELEQLRKELEELSRQISALRKDLARLEA 740

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573   86 QQkmhlEKLEEQLSRSHgQEVNELKTKIEKLKVELDEARLSEKQLkhqvdhqkellscksEELRVMSERVQESMSSEMLA 165
Cdd:TIGR02168  741 EV----EQLEERIAQLS-KELTELEAEIEELEERLEEAEEELAEA---------------EAEIEELEAQIEQLKEELKA 800

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573  166 LQIELTEMESMKTTLKEEVNELQYRQEQLELLITNLMRQVDRLKE----EKEEREKEAVS------YYNALEKARVANQD 235
Cdd:TIGR02168  801 LREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEqieeLSEDIESLAAEieeleeLIEELESELEALLN 880

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573  236 LQVQLDQALQQALDPNSKGNSLFAEVEDRRAAMERQLismkvkyQSLKKQNVFNREQMQRMKLQIATLLQM--KGSQTEF 313
Cdd:TIGR02168  881 ERASLEEALALLRSELEELSEELRELESKRSELRREL-------EELREKLAQLELRLEGLEVRIDNLQERlsEEYSLTL 953

                          330       340
                   ....*....|....*....|....*.
gi 1045561573  314 EQQERLLAMLEQKNGEIKHLLGEIRN 339
Cdd:TIGR02168  954 EEAEALENKIEDDEEEARRRLKRLEN 979
PRK11281 PRK11281
mechanosensitive channel MscK;
23-316 2.86e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 44.13  E-value: 2.86e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573   23 AAQYGLQLVESQNELQNQLDKcrnemMTMTESYEQEKYTLQREVELKSRMLESlsceceaiKQQQKMHLEKLEEQLSRSH 102
Cdd:PRK11281    27 ARAASNGDLPTEADVQAQLDA-----LNKQKLLEAEDKLVQQDLEQTLALLDK--------IDRQKEETEQLKQQLAQAP 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573  103 gQEVNELKTKIEKLKVELDE------ARLSEKQLKHQV--------DHQKELLSCKSE--ELRVMSERVQESMSSEMLAL 166
Cdd:PRK11281    94 -AKLRQAQAELEALKDDNDEetretlSTLSLRQLESRLaqtldqlqNAQNDLAEYNSQlvSLQTQPERAQAALYANSQRL 172

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573  167 QiELTEM-----ESMKTTLKEEVNELQYRQEQLELLI---TNLMRQVDRLKEEKEEREKEAVSYYNALEKARVANQDL-- 236
Cdd:PRK11281   173 Q-QIRNLlkggkVGGKALRPSQRVLLQAEQALLNAQNdlqRKSLEGNTQLQDLLQKQRDYLTARIQRLEHQLQLLQEAin 251

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573  237 -------QVQLDQALQQALDPNSKGNSLFAEVEDRRAAMERQLISMKVKYQSLKKQNVfnreqmqRMKLQIATLLQmkgS 309
Cdd:PRK11281   252 skrltlsEKTVQEAQSQDEAARIQANPLVAQELEINLQLSQRLLKATEKLNTLTQQNL-------RVKNWLDRLTQ---S 321


                   ....*..
gi 1045561573  310 QTEFEQQ 316
Cdd:PRK11281   322 ERNIKEQ 328
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 28-283 3.07e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.90  E-value: 3.07e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573   28 LQLVESQNELQNQLDKCRNEMmtmtESYEQEKYTLQREVELKSRMLESLSCECEAIKQQQ---KMHLEKLEEQLSrSHGQ 104
Cdd:TIGR02169  677 QRLRERLEGLKRELSSLQSEL----RRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEeklKERLEELEEDLS-SLEQ 751

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573  105 EVNELKTKIEKLKVELDEARLSEKQLKHQV-DHQKELLSCKSEELRVMSERVQESMSSEMLALQ---IELTEMESMKTTL 180
Cdd:TIGR02169  752 EIENVKSELKELEARIEELEEDLHKLEEALnDLEARLSHSRIPEIQAELSKLEEEVSRIEARLReieQKLNRLTLEKEYL 831

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573  181 KEEVNELQYRQEQLELLITNLMRQVDRLKEEKEEREKEAVSYYNALEKARVANQDLQVQLDQALQQALDPNSKGNSLFAE 260
Cdd:TIGR02169  832 EKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQ 911

                          250       260
                   ....*....|....*....|...
gi 1045561573  261 VEDRRAAMERQLISMKVKYQSLK 283
Cdd:TIGR02169  912 IEKKRKRLSELKAKLEALEEELS 934
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 66-342 5.53e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.13  E-value: 5.53e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573   66 VELKSRMLESLSCECEAIKQQQKMHLEKLEEQLSrSHGQEVNELKTKIEKLKVELDEARLSEKQLKHQVDHQKELLSCKS 145
Cdd:TIGR02169  193 IDEKRQQLERLRREREKAERYQALLKEKREYEGY-ELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIE 271

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573  146 EELRVMSERVQESMSSEMLALQIELTEMESMKTTLKEEVNELQYRQEQLELLITNLMRQVDRLKEEKEEREKEAVSYYNA 225
Cdd:TIGR02169  272 QLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKR 351

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573  226 LEKARVANQDLQVQLDQALQQALDPNSKGNSLFAEVEDRRAAME---RQLISMKVKYQSLKKQNVFNREQMQRMKLQIAT 302
Cdd:TIGR02169  352 RDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEklkREINELKRELDRLQEELQRLSEELADLNAAIAG 431

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1045561573  303 LLQ--------MKGSQTEFEQQE----RLLAMLEQKNGEIKHLLGEIRNLEK 342
Cdd:TIGR02169  432 IEAkineleeeKEDKALEIKKQEwkleQLAADLSKYEQELYDLKEEYDRVEK 483
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
91-307 8.62e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.59  E-value: 8.62e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573   91 LEKLEEQlsRSHGQEVNELKTKIEKLKVELDEARLSEKQLKHQVDHQK-ELLSCKSEELRVMSERVQEsmssEMLALQIE 169
Cdd:COG4913    244 LEDAREQ--IELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRlELLEAELEELRAELARLEA----ELERLEAR 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573  170 LTEMESMKTTLKEEVNELQYRQ-EQLELLITNLMRQVDRLKEEKEEREKEAVSYYNALEKARVANQDLQVQLDQALQQAL 248
Cdd:COG4913    318 LDALREELDELEAQIRGNGGDRlEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALE 397

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1045561573  249 DPNSKGNSLFAEVEDRRAAMERQLISMKVKYQSLKKQNVFNREQMQRMKLQIATLLQMK 307
Cdd:COG4913    398 EELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALAEALGLD 456
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
15-342 8.87e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.45  E-value: 8.87e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573  15 EAEEERLKAAQYGLQLVESQNELQNQLDKCRNEMMTMTESYEQEKYTLQREVELKSRmLESLSCECEAIKQQQKMHLEKL 94
Cdd:COG4717   108 EAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERLEELEERLEELRELEEE-LEELEAELAELQEELEELLEQL 186

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573  95 ---EEQLSRSHGQEVNELKTKIEKLKVELDEARLSEKQLKHQVDHQKELLSCKSEELRVMSERVQESMSSEMLALQ---- 167
Cdd:COG4717   187 slaTEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLglgg 266

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573 168 ---------------------IELTEMESMKTTLKEEVNELQYRQEQLELLITNLMRQVDRLKEEKEEREKEAVSYYNAL 226
Cdd:COG4717   267 sllsliltiagvlflvlgllaLLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRI 346

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573 227 EKARVANQDLQVQLDQALQQALdpNSKGNSLFAEVEDRRAAMERQLISMKVKYQSLkkqnvfnREQMQRMKLQIATLLQM 306
Cdd:COG4717   347 EELQELLREAEELEEELQLEEL--EQEIAALLAEAGVEDEEELRAALEQAEEYQEL-------KEELEELEEQLEELLGE 417

                         330       340       350
                  ....*....|....*....|....*....|....*.
gi 1045561573 307 KGSQTEFEQQERLLAMLEQKNGEIKHLLGEIRNLEK 342
Cdd:COG4717   418 LEELLEALDEEELEEELEELEEELEELEEELEELRE 453
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
162-349 1.65e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.44  E-value: 1.65e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573  162 EMLALQIELTEMESMKTTLK-----EEVNELQYRQEQLELLITNLMRQVDRLKEEKEEREKEAVSYYNALEKARVAN-QD 235
Cdd:COG4913    263 RYAAARERLAELEYLRAALRlwfaqRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRlEQ 342

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573  236 LQVQLDQALQQAldpnskgnslfAEVEDRRAAMERQLismkvkyQSLKKQNVFNREQMQRMKLQIATLLQMKGSQTE--F 313
Cdd:COG4913    343 LEREIERLEREL-----------EERERRRARLEALL-------AALGLPLPASAEEFAALRAEAAALLEALEEELEalE 404

                          170       180       190
                   ....*....|....*....|....*....|....*.
gi 1045561573  314 EQQERLLAMLEQKNGEIKHLLGEIRNLEKFKNLYDS 349
Cdd:COG4913    405 EALAEAEAALRDLRRELRELEAEIASLERRKSNIPA 440
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 6-437 2.16e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 41.26  E-value: 2.16e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573    6 ITNLRCRLKEAEEERLKAAQYGLQ-LVESQNELQnQLDKCRNEMMTMTESYEQEKYTLQREVELKSRMLESLSCECEAIK 84
Cdd:pfam15921   87 VKDLQRRLNESNELHEKQKFYLRQsVIDLQTKLQ-EMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDML 165

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573   85 QQQKMHLEKLEEQLsRSHGQEVNELKTkiekLKVELDEARlsekqlKHQVDHQKELLSCKSEELRVMSERVQESMSSEML 164
Cdd:pfam15921  166 EDSNTQIEQLRKMM-LSHEGVLQEIRS----ILVDFEEAS------GKKIYEHDSMSTMHFRSLGSAISKILRELDTEIS 234

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573  165 ALQIELTEMESMKTTLKEEvnelqyRQEQLELLitnLMRQVDRLKEEKEEREKEAVSYYNALEKARVANQDLQVQLDQAL 244
Cdd:pfam15921  235 YLKGRIFPVEDQLEALKSE------SQNKIELL---LQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQ 305

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573  245 QQALDPNSKGNSLFAEVEDRRAAMERQLISMKVKY----QSLKKQNVFNREQMQRMKLQIATLLQMKGSQTefEQQERLL 320
Cdd:pfam15921  306 EQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYedkiEELEKQLVLANSELTEARTERDQFSQESGNLD--DQLQKLL 383

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573  321 AMLEQKNGE---------------------IKHLLGEI--RNLE--KFKNLYDSMESKPSVDSGTLEDNTYYTDLLQMKL 375
Cdd:pfam15921  384 ADLHKREKElslekeqnkrlwdrdtgnsitIDHLRRELddRNMEvqRLEALLKAMKSECQGQMERQMAAIQGKNESLEKV 463

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1045561573  376 DNLNKEIESTK-------GELSIQRMKALFESQRALDIERKLFANERCLQLSESENMKLRAKLDeLKLK 437
Cdd:pfam15921  464 SSLTAQLESTKemlrkvvEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVD-LKLQ 531
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2-201 3.52e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 40.43  E-value: 3.52e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573    2 EADIITNLRCRLKEAEEERlkaaqygLQLVESQNELQNQLDKCRnemmTMTESYEQEKYTLQREVELKSRMLESLSCECE 81
Cdd:TIGR02168  766 LEERLEEAEEELAEAEAEI-------EELEAQIEQLKEELKALR----EALDELRAELTLLNEEAANLRERLESLERRIA 834

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573   82 AIKQQqkmhLEKLEEQLSRshgqevneLKTKIEKLKVELDEARLSEKQLKHQVDHQKELLSCKSEELRVMSERvQESMSS 161
Cdd:TIGR02168  835 ATERR----LEDLEEQIEE--------LSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSE-LEELSE 901

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|
gi 1045561573  162 EMLALQIELTEMESMKTTLKEEVNELQYRQEQLELLITNL 201
Cdd:TIGR02168  902 ELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL 941
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
91-267 5.50e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 39.90  E-value: 5.50e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573   91 LEKLEEQLSRShGQEVNELKTKIEKLKVELD---EARLSEKQLKHQVDHQKELLSCKSEELRVMSERVQ-ESMSSEMLAL 166
Cdd:COG4913    612 LAALEAELAEL-EEELAEAEERLEALEAELDalqERREALQRLAEYSWDEIDVASAEREIAELEAELERlDASSDDLAAL 690

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573  167 QIELTEMESMKTTLKEEVNELQYRQEQLELLITNLMRQVDRLKEEKEEREKEAVSYYNALEKARVAN-------QDLQVQ 239
Cdd:COG4913    691 EEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAalgdaveRELREN 770

                          170       180
                   ....*....|....*....|....*...
gi 1045561573  240 LDQALQQAldpNSKGNSLFAEVEDRRAA 267
Cdd:COG4913    771 LEERIDAL---RARLNRAEEELERAMRA 795
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 28-351 7.39e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 39.34  E-value: 7.39e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573  28 LQLVESQNELQNQLDKCRNEMMTMtESYEQEKYTLQREVELKSRMLESLSCECEAIKQQQKMHLEklEEQLSRSHGQEVN 107
Cdd:pfam17380 275 LHIVQHQKAVSERQQQEKFEKMEQ-ERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAE--QERMAMERERELE 351

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573 108 ELKTKIEKLKVEldeaRLSEKQLKHQVDHQKELLSCKSEELRvMSERVQESMSSemlALQIELTEMESMKTTLKEEVNEL 187
Cdd:pfam17380 352 RIRQEERKRELE----RIRQEEIAMEISRMRELERLQMERQQ-KNERVRQELEA---ARKVKILEEERQRKIQQQKVEME 423

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573 188 QYRQEQLELlitnLMRQVDRLKEEKEERekeavsyynaLEKARVANQDLQVQLDQALQQALDPNSKGNSLFAEVEDRRAA 267
Cdd:pfam17380 424 QIRAEQEEA----RQREVRRLEEERARE----------MERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRA 489

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045561573 268 MERQLISMKVKYQSlKKQNVFNREQMQRMKLQiatllQMKGSQTE-FEQQERLLAMLEQKNG----EIKHLLGEIRNLEK 342
Cdd:pfam17380 490 EEQRRKILEKELEE-RKQAMIEEERKRKLLEK-----EMEERQKAiYEEERRREAEEERRKQqemeERRRIQEQMRKATE 563


                  ....*....
gi 1045561573 343 FKNLYDSME 351
Cdd:pfam17380 564 ERSRLEAME 572
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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